ABIN968508

antibody from antibodies-online

Targeting: FUS ALS6, FUS1, hnRNP-P2, HNRNPP2, TLS

Western blot (Data presented on provider website)

Immunocytochemistry (Recommended by provider)

Antibody Data

Product number

ABIN968508

Provider

antibodies-online

Product name

anti-Fused in Sarcoma (FUS) (AA 2-117) antibody

Antibody type

Monoclonal

Antigen

Human TLS .

Description

Purified from tissue culture supernatant or ascites by affinity chromatography.

Reactivity

Human

Host

Mouse

Epitope

AA 2-117

Isotype

IgG

Antibody clone number

Ghr5

Vial size

50 μg

Concentration

250 μg/ml

Storage

-20°C

References

Submitted references

Oncoprotein TLS interacts with serine-arginine proteins involved in RNA splicing.

Yang L, Embree LJ, Tsai S, Hickstein DD
The Journal of biological chemistry 1998 Oct 23;273(43):27761-4

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Genomic structure of the human RBP56/hTAFII68 and FUS/TLS genes.

Morohoshi F, Ootsuka Y, Arai K, Ichikawa H, Mitani S, Munakata N, Ohki M
Gene 1998 Oct 23;221(2):191-8

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TLS (translocated-in-liposarcoma) is a high-affinity interactor for steroid, thyroid hormone, and retinoid receptors.

Powers CA, Mathur M, Raaka BM, Ron D, Samuels HH
Molecular endocrinology (Baltimore, Md.) 1998 Jan;12(1):4-18

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The transcription factor Spi-1/PU.1 interacts with the potential splicing factor TLS.

Hallier M, Lerga A, Barnache S, Tavitian A, Moreau-Gachelin F
The Journal of biological chemistry 1998 Feb 27;273(9):4838-42

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TLS (FUS) binds RNA in vivo and engages in nucleo-cytoplasmic shuttling.

Zinszner H, Sok J, Immanuel D, Yin Y, Ron D
Journal of cell science 1997 Aug;110 ( Pt 15):1741-50