Tissue expression
Cell line expression
Protein structure
FUS
FUS RNA binding proteinALS6, FUS1, hnRNP-P2, HNRNPP2, TLS
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009]
Top validated antibodies |
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| Proteintech Group | 117 references | Polyclonal |
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| Invitrogen Antibodies | 6 references | Polyclonal |
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| Atlas Antibodies | 42 references | Polyclonal |
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| Novus Biologicals | 18 references | Polyclonal |
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| antibodies-online | 2 references | Polyclonal |
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