Antibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [4]
- ELISA [1]
- Immunohistochemistry [1]
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- Product number
- ABIN395943 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1) (AA 652-754) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Epitope
- AA 652-754
- Isotype
- IgG
- Antibody clone number
- 3D2
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population.
Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Association of PCSK1 rs6234 with obesity and related traits in a Chinese Han population.
Solution structure of proinsulin: connecting domain flexibility and prohormone processing.
Association of obesity risk SNPs in PCSK1 with insulin sensitivity and proinsulin conversion.
Fontaine-Bisson B, Renström F, Rolandsson O, MAGIC., Payne F, Hallmans G, Barroso I, Franks PW
Diabetologia 2010 Oct;53(10):2155-62
Diabetologia 2010 Oct;53(10):2155-62
Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators.
Diabetes care 2010 Oct;33(10):2250-3
Diabetes care 2010 Oct;33(10):2250-3
Association of PCSK1 rs6234 with obesity and related traits in a Chinese Han population.
Qi Q, Li H, Loos RJ, Liu C, Hu FB, Wu H, Yu Z, Lin X
PloS one 2010 May 17;5(5):e10590
PloS one 2010 May 17;5(5):e10590
Solution structure of proinsulin: connecting domain flexibility and prohormone processing.
Yang Y, Hua QX, Liu J, Shimizu EH, Choquette MH, Mackin RB, Weiss MA
The Journal of biological chemistry 2010 Mar 12;285(11):7847-51
The Journal of biological chemistry 2010 Mar 12;285(11):7847-51
Association of obesity risk SNPs in PCSK1 with insulin sensitivity and proinsulin conversion.
Heni M, Haupt A, Schäfer SA, Ketterer C, Thamer C, Machicao F, Stefan N, Staiger H, Häring HU, Fritsche A
BMC medical genetics 2010 Jun 9;11:86
BMC medical genetics 2010 Jun 9;11:86
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Supportive validation
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC