AUH

gene product
The methylglutaconyl-CoA hydratase, mitochondrial protein binds to the AU-rich element (ARE), a common element found in the 3' UTR of rapidly decaying mRNA such as c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. AUH is also homologous to enol-CoA hydratase, an enzyme involved in fatty acid degradation, and has been shown to have intrinsic hydratase enzymatic activity. AUH is thus a bifunctional chimera between RNA binding and metabolic enzyme activity. A possible subcellular localization in the mitochondria has been demonstrated for the mouse homolog of this protein which shares 92% identity with the human protein. It has been suggested that AUH may have a novel role as a mitochondrial located AU-binding protein. Human AUH is expressed as a single mRNA species of 1.8 kb, and translated as a 40-kDa precursor protein which is subsequently processed to a 32-kDa mature form. [provided by RefSeq, May 2010]
More gene data

Featured antibodies

Antibodies

 

Filters

Antibodypedia Validation Initiative

Validation method

Application

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
100 antibodies from 25 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeAVIWBELICCIPIHCFC
LifeSpan BioSciences, Inc.
22 antibodies
NovoPro Bioscience Inc.
1 antibody
Proteintech Group
1 antibody
Novus Biologicals
4 antibodies
antibodies-online
18 antibodies
Biorbyt
3 antibodies
Aviva Systems Biology
4 antibodies
GeneTex
3 antibodies
OriGene
2 antibodies
Atlas Antibodies
1 antibody
Invitrogen Antibodies
3 antibodies
Bioworld Technology, Inc
1 antibody
Boster Biological Technology
1 antibody
ProSci
1 antibody
St John's Laboratory
1 antibody
Acris Antibodies GmbH
3 antibodies
Abnova Corporation
5 antibodies
Creative Diagnostics
3 antibodies
RabMAbs
2 antibodies
Creative Biolabs
2 antibodies
United States Biological
13 antibodies
Sigma-Aldrich
3 antibodies
MyBioSource
1 antibody
Abgent
1 antibody
GenWay
1 antibody