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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- PAB4575 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB4575, RRID:AB_1579112
- Product name
- PRKAB1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of PRKAB1.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references AMP-activated protein kinase plays a role in the control of food intake.
C75, a fatty acid synthase inhibitor, modulates AMP-activated protein kinase to alter neuronal energy metabolism.
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus.
Andersson U, Filipsson K, Abbott CR, Woods A, Smith K, Bloom SR, Carling D, Small CJ
The Journal of biological chemistry 2004 Mar 26;279(13):12005-8
The Journal of biological chemistry 2004 Mar 26;279(13):12005-8
C75, a fatty acid synthase inhibitor, modulates AMP-activated protein kinase to alter neuronal energy metabolism.
Landree LE, Hanlon AL, Strong DW, Rumbaugh G, Miller IM, Thupari JN, Connolly EC, Huganir RL, Richardson C, Witters LA, Kuhajda FP, Ronnett GV
The Journal of biological chemistry 2004 Jan 30;279(5):3817-27
The Journal of biological chemistry 2004 Jan 30;279(5):3817-27
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus.
Minokoshi Y, Alquier T, Furukawa N, Kim YB, Lee A, Xue B, Mu J, Foufelle F, Ferré P, Birnbaum MJ, Stuck BJ, Kahn BB
Nature 2004 Apr 1;428(6982):569-74
Nature 2004 Apr 1;428(6982):569-74
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- The PRKAB1 polyclonal antibody (Cat # PAB4575) is used in Western blot to detect PRKAB1 in Jurkat cell lysate .
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- The PRKAB1 polyclonal antibody (Cat # PAB4575) is used in Western blot to detect PRKAB1 in mouse spleen tissue lysate .
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with PRKAB1 polyclonal antibody (Cat # PAB4575) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated . HC = hepatocarcinoma .
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
