PRKAB1

gene product
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq, Jul 2008]
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548 antibodies from 38 providers.

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AntibodyRefsTypeAVIWBELICCIPIHCFC
antibodies-online
152 antibodies
LifeSpan BioSciences, Inc.
77 antibodies
OriGene
11 antibodies
Arigo
1 antibody
Atlas Antibodies
1 antibody
Invitrogen Antibodies
10 antibodies
Abnova Corporation
13 antibodies
NovoPro Bioscience Inc.
7 antibodies
Novus Biologicals
7 antibodies
St John's Laboratory
12 antibodies
Biorbyt
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GeneTex
7 antibodies
Bioworld Technology, Inc
5 antibodies
Cell Signaling Technology, Inc
4 antibodies
Affinity Biosciences
4 antibodies
Aviva Systems Biology
7 antibodies
Abgent
8 antibodies
Acris Antibodies GmbH
9 antibodies
NSJ Bioreagents
2 antibodies
R&D Systems
1 antibody
RabMAbs
7 antibodies
Proteintech Group
1 antibody
Abbkine Scientific Co.Ltd.
5 antibodies
BioLegend
2 antibodies
Creative Diagnostics
6 antibodies
MyBioSource
12 antibodies
Creative Biolabs
2 antibodies
EMD Millipore
2 antibodies
Abbexa
1 antibody
Abbiotec
1 antibody
Signalway Antibody LLC
1 antibody
United States Biological
100 antibodies
RayBiotech, Inc.
3 antibodies
Boster Biological Technology
2 antibodies
Abiocode, Inc.
1 antibody
Sigma-Aldrich
3 antibodies
ProSci
1 antibody