Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN2845096 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Betacellulin (BTC) (AA 17-45), (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 17-45, N-Term
- Antibody clone number
- RB14431
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references Sequential and gamma-secretase-dependent processing of the betacellulin precursor generates a palmitoylated intracellular-domain fragment that inhibits cell growth.
Betacellulin inhibits osteogenic differentiation and stimulates proliferation through HIF-1alpha.
A betacellulin mutant promotes differentiation of pancreatic acinar AR42J cells into insulin-producing cells with low affinity of binding to ErbB1.
ErbB/HER ligands in human breast cancer, and relationships with their receptors, the bio-pathological features and prognosis.
The ADAM10 prodomain is a specific inhibitor of ADAM10 proteolytic activity and inhibits cellular shedding events.
Stoeck A, Shang L, Dempsey PJ
Journal of cell science 2010 Jul 1;123(Pt 13):2319-31
Journal of cell science 2010 Jul 1;123(Pt 13):2319-31
Betacellulin inhibits osteogenic differentiation and stimulates proliferation through HIF-1alpha.
Genetos DC, Rao RR, Vidal MA
Cell and tissue research 2010 Apr;340(1):81-9
Cell and tissue research 2010 Apr;340(1):81-9
A betacellulin mutant promotes differentiation of pancreatic acinar AR42J cells into insulin-producing cells with low affinity of binding to ErbB1.
Nagaoka T, Fukuda T, Hashizume T, Nishiyama T, Tada H, Yamada H, Salomon DS, Yamada S, Kojima I, Seno M
Journal of molecular biology 2008 Jun 27;380(1):83-94
Journal of molecular biology 2008 Jun 27;380(1):83-94
ErbB/HER ligands in human breast cancer, and relationships with their receptors, the bio-pathological features and prognosis.
RĂ©villion F, Lhotellier V, Hornez L, Bonneterre J, Peyrat JP
Annals of oncology : official journal of the European Society for Medical Oncology 2008 Jan;19(1):73-80
Annals of oncology : official journal of the European Society for Medical Oncology 2008 Jan;19(1):73-80
The ADAM10 prodomain is a specific inhibitor of ADAM10 proteolytic activity and inhibits cellular shedding events.
Moss ML, Bomar M, Liu Q, Sage H, Dempsey P, Lenhart PM, Gillispie PA, Stoeck A, Wildeboer D, Bartsch JW, Palmisano R, Zhou P
The Journal of biological chemistry 2007 Dec 7;282(49):35712-21
The Journal of biological chemistry 2007 Dec 7;282(49):35712-21
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