Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- BAF261 - Provider product page
- Provider
- R&D Systems
- Product name
- Human Betacellulin/BTC Biotinylated Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human Betacellulin in ELISAs and Western blots. In Western blots, less than 1% cross-reactivity with recombinant human (rh) HB-EGF, rhEGF, rhTGF-alpha , rhHRG-alpha , and rhAmphiregulin is observed.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Biotin
- Antigen sequence
P35070
- Isotype
- IgG
- Vial size
- 50 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Effects of neuregulin GGF2 (cimaglermin alfa) dose and treatment frequency on left ventricular function in rats following myocardial infarction.
Glial growth factor 2 promotes functional recovery with treatment initiated up to 7 days after permanent focal ischemic stroke.
Remission of diabetes by beta-cell regeneration in diabetic mice treated with a recombinant adenovirus expressing betacellulin.
Hydrogen peroxide and endothelin-1 are novel activators of betacellulin ectodomain shedding.
Parry TJ, Ganguly A, Troy EL, Luis Guerrero J, Iaci JF, Srinivas M, Vecchione AM, Button DC, Hackett CS, Zolty R, Sawyer DB, Caggiano AO
European journal of pharmacology 2017 Feb 5;796:76-89
European journal of pharmacology 2017 Feb 5;796:76-89
Glial growth factor 2 promotes functional recovery with treatment initiated up to 7 days after permanent focal ischemic stroke.
Iaci JF, Ganguly A, Finklestein SP, Parry TJ, Ren J, Saha S, Sietsma DK, Srinivas M, Vecchione AM, Caggiano AO
Neuropharmacology 2010 Dec;59(7-8):640-9
Neuropharmacology 2010 Dec;59(7-8):640-9
Remission of diabetes by beta-cell regeneration in diabetic mice treated with a recombinant adenovirus expressing betacellulin.
Shin S, Li N, Kobayashi N, Yoon JW, Jun HS
Molecular therapy : the journal of the American Society of Gene Therapy 2008 May;16(5):854-61
Molecular therapy : the journal of the American Society of Gene Therapy 2008 May;16(5):854-61
Hydrogen peroxide and endothelin-1 are novel activators of betacellulin ectodomain shedding.
Sanderson MP, Abbott CA, Tada H, Seno M, Dempsey PJ, Dunbar AJ
Journal of cellular biochemistry 2006 Oct 1;99(2):609-23
Journal of cellular biochemistry 2006 Oct 1;99(2):609-23
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