ABIN655615

antibody from antibodies-online

Targeting: BTC

Western blot (Recommended by provider)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

ABIN655615

Provider

antibodies-online

Product name

anti-Betacellulin (BTC) (AA 17-45), (N-Term) antibody

Antibody type

Polyclonal

Description

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Reactivity

Human

Host

Rabbit

Epitope

AA 17-45, N-Term

Antibody clone number

RB14431

Vial size

400 μL

Storage

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

References

Submitted references

Sequential and gamma-secretase-dependent processing of the betacellulin precursor generates a palmitoylated intracellular-domain fragment that inhibits cell growth.

Stoeck A, Shang L, Dempsey PJ
Journal of cell science 2010 Jul 1;123(Pt 13):2319-31

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Betacellulin inhibits osteogenic differentiation and stimulates proliferation through HIF-1alpha.

Genetos DC, Rao RR, Vidal MA
Cell and tissue research 2010 Apr;340(1):81-9

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A betacellulin mutant promotes differentiation of pancreatic acinar AR42J cells into insulin-producing cells with low affinity of binding to ErbB1.

Nagaoka T, Fukuda T, Hashizume T, Nishiyama T, Tada H, Yamada H, Salomon DS, Yamada S, Kojima I, Seno M
Journal of molecular biology 2008 Jun 27;380(1):83-94

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ErbB/HER ligands in human breast cancer, and relationships with their receptors, the bio-pathological features and prognosis.

Révillion F, Lhotellier V, Hornez L, Bonneterre J, Peyrat JP
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2008 Jan;19(1):73-80

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The ADAM10 prodomain is a specific inhibitor of ADAM10 proteolytic activity and inhibits cellular shedding events.

Moss ML, Bomar M, Liu Q, Sage H, Dempsey P, Lenhart PM, Gillispie PA, Stoeck A, Wildeboer D, Bartsch JW, Palmisano R, Zhou P
The Journal of biological chemistry 2007 Dec 7;282(49):35712-21