PPEF2

This gene encodes a member of the serine/threonine protein phosphatase with EF-hand motif family. The protein contains a protein phosphatase catalytic domain, and at least two EF-hand calcium-binding motifs in its C terminus. Although its substrate(s) is unknown, the encoded protein, which is expressed specifically in photoreceptors and the pineal, has been suggested to play a role in the visual system. This gene shares high sequence similarity with the Drosophila retinal degeneration C (rdgC) gene. [provided by RefSeq, Jul 2008]

Description

Protein phosphatase with EF-hand domain 2

Tissue specificity

Tissue enriched (retina)

Predicted location

Intracellular

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)

Chromosome

4 (75859864 - 75902571)

Ensembl ID

ENSG00000156194  (ver. 103.38)

Orthologs

Mouse Ppef2: ENSMUSG00000029410

UniProt

O14830

neXtProt

NX_O14830

Human splice variants
Mouse splice variants

Protein structure