WDR6

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. The encoded protein interacts with serine/threonine kinase 11, and is implicated in cell growth arrest. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]

Description

WD repeat domain 6

Tissue specificity

Low tissue specificity

Subcell location

Plasma membrane, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)

Chromosome

3:p21.31 (49007062 - 49015953)

Ensembl ID

ENSG00000178252  (ver. 103.38)

Orthologs

Mouse Wdr6: ENSMUSG00000066357

UniProt

Q9NNW5

neXtProt

NX_Q9NNW5

Human splice variants
Mouse splice variants