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- Antibody Data
- Antigen structure
- References [2993]
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- Immunoprecipitation [1]
- Immunohistochemistry [2]
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- Product number
- 20874-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20874-1-AP, RRID:AB_10697811
- Product name
- E-cadherin antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated E-cadherin antibody (Cat. #20874-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A novel Nilotinib derivative N-12 inhibits the proliferation and migration of colon cancer cells through the EMT signaling pathway.
Versatile Nanotherapeutics for Enhancing Sonodynamic Therapy/Chemotherapy of Thyroid Cancer through Remodeling Tumor Microenvironment and Synergistic Reactive Oxygen Species Augment.
THBS3 Functions as a Novel Biomarker for Prognosis and Immunotherapeutic Response in Colorectal Cancer: An Integrative Analysis and Validation of the Thrombospondin Gene Family.
Co-targeting MRPS7-23 synergistically enhances cisplatin efficacy to suppress nasopharyngeal carcinoma growth and metastasis.
LncRNA VCAN-AS1 Sponges miR-374c-3p to Promote Proliferation, Invasion, Migration, and EMT in Thyroid Cancer.
Yifei Decoction Regulates the NGF/TRKA/PI3K/AKT Signaling Axis to Inhibit the Epithelial-Mesenchymal Transformation and Proliferation of Pulmonary Epithelial Cells in Bleomycin-Induced Pulmonary Fibrogenesis.
Tuft Cells in the Gut Limit Cognitive Disorders by Regulating Gut Homeostasis.
Berberine Ameliorates Diabetic Kidney Disease by Modulating Macrophage Polarization via Inhibiting IL-17A Signaling.
GNPAT promotes immunosuppression in hepatocellular carcinoma by activating the plasmalogen-PPARγ pathway to drive M2 macrophage polarization.
The prognostic significance of JAML and its role in remodeling the immune microenvironment via the cGAS-STING pathway in endometrial cancer.
Targeting CPS1 attenuates lung cancer metastasis by regulating EMT through an epigenetic mechanism.
A novel mouse cell line model reveals the tumor intrinsic and immune characteristics of EGFR-mutant lung cancer.
Macrophage-Derived Transcriptional Signatures Predict Prognosis and Drug Sensitivity in Thyroid Cancer: Integrative Analysis and Experimental Validation of SMYD3.
Hydroxysafflor Yellow A improves diabetic nephropathy by inhibiting PI3K/AKT/mTOR pathway based on a multidimensional study.
Endothelial SMAD1-MCAM axis facilitates sunitinib resistance and progression of clear cell renal cell carcinoma via LAMB1-ITGB1 signaling.
ATP-binding cassette subfamily A member 5 suppresses pancreatic ductal adenocarcinoma progression and chemoresistance by promoting β-catenin ubiquitin-dependent degradation.
RNA‑binding protein DAZAP1 promotes gastric cancer metastasis by enhancing NOTCH1 and JAG1 mRNA stability.
PLOD2 Promotes Cutaneous Squamous Cell Carcinoma Progression in Association With STAT3-Related ERK and AKT Pathways.
Plasmin promotes hepatocellular carcinoma invasion and metastasis via CXCR4-mediated activation of PI3K/AKT/mTOR signaling.
Development of a self-assembling aggregation-induced emission nanoprobe for targeted therapy and real-time imaging in non-small cell lung cancer.
Differences in palatal shelf epithelial stiffness between the lingual/nasal and buccal/oral surfaces during palatal shelf elevation in developing mice.
Peroxiredoxin 4 suppresses ferroptosis in esophageal squamous cell carcinoma by activating the phosphoinositide 3-kinase signaling pathway.
m⁶A-modified circMELK regulates nasopharyngeal carcinoma progression via a YTHDF1/circMELK-miR-4775-HMGA2 feedback loop.
Bufei Jianspi formula alleviates intestinal epithelial barrier injury by inhibition of calpain 2 in COPD rat.
Study on the anti-pulmonary fibrosis mechanism of Renshen Pingfei formula by inhibiting M2 macrophage polarization and regulating TGF - β/SMAD signaling pathway.
Prenylterphenyllin, a regulator of P53, inhibits colorectal cancer progression through oxidative stress and energy metabolism pathway.
ENO1 inhibition synergizes with chidamide to induce ferroptosis in PTCL-NOS through metabolic remodeling.
Oncogenic role of talin-1 in glioma: Association with poor prognosis and regulation of the TGF-beta signaling pathway.
Natural compound 5,7,8‑trimethoxyflavone mitigates radiation‑induced lung injury by suppressing EMT and PI3K/Akt pathway.
Homoharringtonine inhibits growth and migration in non-small cell lung cancer via PDIA4-mediated modulation of autophagy and EMT.
Promotion of hepatocellular carcinoma by small nuclear ribonucleoprotein polypeptide F through upregulation of transmembrane P24 trafficking protein 2 and triggering of the cGAS-STING pathway.
Novel nanoparticle-combined therapy through EGFR and PD-L1 blockade: PFPR-siRNA-mediated suppressing NSCLC proliferation via PDT and enhanced antitumor immunity.
Astaxanthin alleviates DSS-induced ulcerative colitis in mice associated with Nrf2-mediated ferroptosis independently of gut microbiota modulation.
TRIM35 inhibits endometrial cancer progression via ubiquitination and degradation of EIF3E.
UBR5 regulates the progression of colorectal cancer cells through Snail-induced epithelial-mesenchymal transition.
ANO6 Confers Paclitaxel Resistance by Targeting Ferroptosis in Cervical Cancer.
An integrated network pharmacology and proteomics approach reveals the anti-fibrotic effect of Fushen Granule on peritoneal fibrosis.
PIEZO1 enhances pancreatic cancer neurotropism.
WISP2 Overexpression Is Associated with Reduced Vasculogenic Mimicry and Epithelial-Mesenchymal Transition in Gastric Cancer.
AI-enabled single-cell dissection of the palmitoylation landscape identifies a multicellular prognostic program in gastric cancer.
Kukoamine B Inhibits EMT in Lung Adenocarcinoma Cells by Regulating Intracellular PD-L1-Mediated p65 Nuclear Translocation.
Activation of the PI3K/AKT pathway by EDIL3 induces EMT and promotes tumor progression in clear cell renal cell carcinoma.
TFAP2A regulates SGPP2 transcription to promote lipid accumulation and activate the Wnt/β-catenin signaling pathway to promote malignant progression in lung adenocarcinoma.
Clonal Stabilization Reveals a DAO/3MST-Expressing MDCK Subpopulation With Robust d-Cysteine-Mediated H(2)S Production.
BHMT Protects Against Diabetic Cataracts by Reducing Homocysteine and Counteracting Endoplasmic Reticulum Stress in Lens Epithelial Cells.
lnc-ALX1-2:10 is a novel regulator that enhances proliferation, migration and invasion in prostate cancer cells.
Multi-omics analysis of NEDD1 in hepatocellular carcinoma: biological function, prognostic value, and clinical significance.
Perfluorocarbon ameliorates high-altitude pulmonary edema and blood-gas barrier dysfunction in a canine model and a lung-on-chip model by suppressing the HIF-1α/HO-1 pathway.
Spiky Nanoparticle-Gel Composite for Efficient Intravesical Botulinum Toxin A Delivery and Treatment of Overactive Bladder.
Mechanism of LPS-activated gingival fibroblasts promote the migration of gastric cancer cells via CXCL12/CXCR4-Snail2-EMT axis.
Mechanistic study of miR-486-5p targeting Claudin-10 in placenta accreta spectrum pathogenesis and its impact on trophoblast behavior.
Tannic Acid Inhibits Lung Adenocarcinoma Progression by Suppressing MMP-2-Mediated Epithelial-Mesenchymal Transition.
Hydrogen sulfide ameliorates oxalate crystal-related renal injury via inhibiting the activation of NOD-like receptor thermal protein domain associated protein 3 inflammasome in mice.
The APC/C subunit APC7 promotes hepatocellular carcinoma progression by mediating ubiquitination and degradation of LATS1 to activate YAP/TAZ.
Curculigoside attenuates influenza virus-induced acute lung injury by modulating the Keap1/Nrf2 signaling pathway.
USP1 promotes hepatocellular carcinoma progression by modulating mitophagy via stabilizing MCM3 to regulate the Keap1-Nrf2 axis.
USP5-mediated CD73 deubiquitination drives osimertinib resistance via PI3K/AKT and glycolysis activation in LUAD.
SGK1 Is Upregulated in Retained Placenta and Mediates Estradiol Effects in Bovine Endometrial Cells.
FUT8 reprograms glycolytic metabolism to promote PKM2 lactylation and drive clear cell renal cell carcinoma progression.
B3GNT3 facilitates NFKB2 processing and non-canonical NF-κB activation to drive lung adenocarcinoma progression.
Far Infrared Radiation Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice via Modulation of the p53/TGF-β Signaling Pathway.
Highly Ca(2+)-permeable transient receptor potential vanilloid 6 contributes to the protection against colitis by regulating epithelial barrier function.
RRP9 suppresses hepatocellular carcinoma progression by inhibiting the PI3K/AKT/mTOR pathway.
Mechanism of HAND2 Regulating Glycolytic Metabolism and Metastasis Through TLR4/NOX2/DUOX2 Signaling Axis in Cervical Cancer.
Phosphoethanolamine cytidylyltransferase 2 exerts an anti-tumor role in clear cell renal cell carcinoma by modulating the hippo/YAP1 signaling pathway in a PPP2R1A-dependent manner.
Mechanical cues regulate in vitro implantation of mouse embryos.
Overexpression and knockdown of 5-lipoxygenase regulates the migration and invasion of colorectal cancer cells.
cGAS-STING signaling pathway promotes ischemic kidney injury by regulating HK3-mediated lipid accumulation.
MEHP promotes breast cancer progression via GPR30-mediated epithelial-mesenchymal transition.
Inhibition of GRK2 mitigates cisplatin-induced acute and chronic nephrotoxicity by targeting the NADPH oxidase 4/oxidative stress axis.
HOMER3 as a prognostic and immune-related biomarker in pan-cancer and esophageal carcinoma: Insights from bioinformatics and functional validation.
The role of FPR3 in remodeling the immune microenvironment and lung metastasis of colon adenocarcinoma.
Therapeutic mechanism of Changyong Decoction in suppressing colorectal cancer progression and inducing ferroptosis via the PIEZO1-PI3K/AKT signaling axis.
Syntaphilin inhibits glioma invasion via modulating mitochondria redistribution and shapes the immune microenvironment: A potential prognostic biomarker.
Comprehensive S-acylation profiling of the porcine epididymis and exosomes reveals a role in cargo sorting and long-distance trafficking.
Immune-epithelial dual-targeting bilirubin nanoparticles for acute lung injury.
IGHG1(+) malignant epithelial Cell-myCAF crosstalk via MIF-CD74/APP-CD74 drives early brain metastasis in NSCLC: Delineated via primary tumor-brain metastasis single-cell and spatial transcriptomics.
Hyaluronic acid-based reactive oxygen species responsive nanocomposite hydrogel for sequential drug delivery and effective prevention of postoperative abdominal adhesions.
A positive SPTBN2-FLI1 feedback axis promotes bladder cancer via PI3K/AKT activation.
Targeting the NR5A1-KISS1R-EMT axis with a small-molecule inhibitor suppresses lung adenocarcinoma progression and metastasis.
Identification of PLXNC1 as a novel biomarker for consensus molecular subtype 4 in colorectal cancer.
GLT8D2-mediated PD-L1 N-glycosylation promotes tumor immune evasion in ovarian cancer peritoneal metastasis.
Transmembrane Protein TMEM59L Modulates 5-FU Resistance via PTPRN-Mediated DNA Damage Repair in Colorectal Cancer.
Metformin attenuates colitis via blocking STAT3 acetylation by reducing acetyl-CoA production.
Basement membrane-associated gene P3H2 regulates osteosarcoma progression and epithelial-mesenchymal transition through AKT/mTOR signaling axis.
Narirutin Reprograms Fatty Acid Metabolism and Inhibits Tumorigenesis via Downregulating ADORA3 Expression in Colorectal Cancer.
Bacterial cellulose repairs asthmatic epithelial injury by reprogramming CDS1-mediated phosphatidylinositol metabolism to inhibit PI3K/AKT signaling.
TRIM32 promotes anoikis resistance and metastasis in NSCLC by degrading CHEK2 to enhance IL-6 secretion.
Downregulation of BST2 Rescues Cochlear Nerve Demyelination in Age-Related Hearing Loss via Enhancing Schwann Cell Migration.
Silence of circPLK1 inhibits NSCLC progression by regulating the miR-1294/SLC16A9 axis.
Unraveling the active ingredients and molecular mechanisms of Qinghua Changyan granule against irritable bowel syndrome with diarrhea: Effects on gut microbiota and glutamine transport via an integrative approach combining UHPLC-MS/MS and experimental verification.
CypA Mediates Non-Small Cell Lung Cancer Chemoresistance by Attenuating Ferroptosis via Stabilizing SLC7A11.
SIGLEC15 modulates the immunosuppressive microenvironment and suppresses malignant phenotypes in triple-negative breast cancer.
Membrane potential mediates the cellular response to mechanical pressure.
NAT10-mediated ac4C modifications regulate glioblastoma progression.
HSP90AA1 restrains clear cell renal cell carcinoma progression by promoting CADM1 expression and suppressing the PI3K-AKT pathway through interaction with FBXO7.
GLCCI1 alleviates airway remodeling in asthmatic mice by inhibiting ZEB1-mediated epithelial-mesenchymal transition.
EIF4A3/circPTGR1/miR-4725-5p positive- feedback loop promotes colorectal cancer progression via FAK/AKT signaling pathway.
PPIA regulates fatty acid and glutamine metabolism in lung adenocarcinoma based on multiomics prognostic model and experiment validation.
Artemisinin-hydroxychloroquine combination from traditional antimalarial medicine attenuates pulmonary fibrosis via PI3K/AKT/GSK3β-mediated inhibition of epithelial-mesenchymal transition.
Isobavachalcone ameliorates TNBS-induced Crohn's disease-like colitis via GPR84-PI3K-AKT axis.
SCHEMBL4796824: a multifaceted antitumor agent targeting microtubule dynamics, DNA damage, and Wnt/β-catenin signaling in ovarian cancer cells.
SULT1E1 exerts a protective role in COPD by inhibiting the AKT pathway: an in vivo and in vitro study.
Mechanistic Language Modeling and Oxygenated 3D Screening Reveal Berberine and Enzalutamide Synergy in Resistant Prostate Cancer.
Inhibition of the RORC/GPX4 mediated ferroptosis regulatory axis suppresses tumor growth and alleviates enzalutamide resistance in prostate cancer.
Antitumor Effects of Broadleaf Vetch Against Esophageal Squamous Cell Carcinoma Through Dual Mechanisms: Suppressing EMT and Inducing Ferroptosis with Predicted Hepatorenal Toxicity-An Integrative Network Pharmacology and Toxicology Study.
Hypoxic glycolysis-driven histone lactylation activates NHE7 to promote endometrial cancer progression via COX6C-mediated endoplasmic reticulum stress.
SPIB suppresses protective autophagy via the IFIT2/PINK1/Parkin axis to promote anoikis in colorectal cancer.
Establishing a Non-Surgical Mouse Model of Laryngopharyngeal Reflux Disease: Acid-Induced Epithelial Disruption and Protective Role of N-Acetylcysteine.
Clinical significance of CXCL17 in cervical cancer.
HOXB4 Promotes Bladder Cancer Progression in Part Through Transcriptional Activation of Smoothened.
BCAR3 Hypomethylation as a Potential Diagnostic Marker for Thyroid Cancer and Its Mechanism via Promoting EMT and AKT/mTOR Pathway.
Methylation-induced silencing of AZGP1 enhances prostate cancer metastasis by stimulating tumoral glycolysis.
Cuproptosis of bronchial epithelial cells triggers airway remodeling in chronic asthma.
HPGDS promotes tubular injury and interstitial inflammation in diabetic nephropathy by activating canonical pyroptosis pathway.
Linarin Suppresses the Progression of Colorectal Cancer by Inhibiting the HIF-1α/PD-L1 Axis.
Shionone ameliorates pulmonary fibrosis by activating mitophagy via PINK1-Parkin pathway.
Dynamin-Related Protein 1-Dependent Disruption of Mitochondrial Homeostasis Drives Blue Light-Induced Epithelial-Mesenchymal Transition in Retinal Aging.
3-Deoxy-3β-syringoylamino-betulinic acid Reduces Breast Tumor Growth and Lung Colonization, With Associated Downregulation of the RAS/RAF/MEK/ERK Pathway.
HIF-2α / HILPDA promotes ferroptosis sensitivity in placenta trophoblast cells of early-onset preeclampsia.
Differentiating Damp-Heat and Cold-Damp Diarrhea in Rat Models via Gut Microbiota Dysbiosis and Short-Chain Fatty Acid Profiling.
COL1A1 promotes clear cell renal cell carcinoma progression through the Wnt/β-catenin signaling pathway.
Acute sleep deprivation reduces thermotolerance and exacerbates heat stroke via disruption of intestinal barrier integrity in rats.
Polystyrene Microplastics Exposure Aggravates Clear Cell Renal Cell Carcinoma Progression via the NF-κB and TGF-β Signaling Pathways.
Lipid Nanoparticles Enable Efficient EGF mRNA Delivery for Wound Healing.
Discovery of novel small molecule inhibitor targeting the tumor promoting effect of transcription factor PLAGL2.
Interleukin-7 induces EMT to promote tumor growth and metastasis in NSCLC via Notch1/TGF-β pathway.
Engineered CCR2 Cell Membrane-Wrapped Cepharanthine Liposomes for Potential Targeted Attenuation of Acute Lung Injury.
Exosomal microRNAs of tuberculous pleural effusion orchestrating TGF-β signaling mediate pleural fibrosis.
VAMP7 governs ferroptosis suppression and cisplatin resistance in esophageal cancer: a dual-targeting therapeutic paradigm.
DMBX1 expression in colon cancer and its impact on prognosis and the tumor microenvironment.
Fibroblast Growth Factor 11 Improves Fertility by Alleviating Intrauterine Adhesionss in Rats Through Inhibition of the Transforming Growth Factor-β1/Smad Pathway.
Fecal microbiota transplantation reduces susceptibility to post-antibiotic CLP-induced sepsis by modulating the gut microbiota and its metabolites.
TMT proteomics reveals that miR-425-5p promotes proliferation and metastasis of malignant melanoma by inhibiting SCARA5.
ACTG1 facilitates proliferation and epithelial-mesenchymal transition-mediated metastasis via COL21A1 in gastric cancer.
Functional effects of EpCAM N-glycosylation in MDA-MB-468 breast cancer cells.
AMPK Deficiency Induces Corneal Epithelial Barrier Dysfunction by Modulating Energy Homeostasis.
PARP-1 couples β-catenin/TCF4 signaling to epithelial-mesenchymal transition in endometriosis.
CD177(+) neutrophils alleviate acute pancreatitis-associated lung injury by protecting colonic barrier and restoring gut microbiota.
SREBP1 knockdown triggers ferroptosis by suppressing the Nrf2-XCT/GPX4 axis in ovarian cancer.
Growth differentiation factor 15 promotes the malignant progression of multiple myeloma via activation of PI3K/Akt/NF-κB signaling pathway.
Mitochondrial uncoupling sensitizes gastric cancer cells to elesclomol-induced cuproptosis via FDX1/DLAT upregulation.
Cadmium exposure induces renal fibrosis by inhibiting hsa_circ_0075684/miR-363-3p/KLF4 signaling pathway.
Development and characterization of immortalized mouse intestinal epithelial cell lines.
Gingerenone A ameliorates airway inflammation and remodeling in asthma by modulating the TLR4/MyD88/NF-κB pathway.
The circadian clock component PER2 deficiency aggravates airway epithelial remodeling through Wnt/β-catenin signaling pathway.
Identification and biological evaluation of benzimidazole-based compounds as novel TGFβR1 inhibitors.
Identification of mitochondrial permeability transition-related gene signatures to predict lung adenocarcinoma survival and drug response.
The P7 peptide antagonizes bFGF-induced malignant behaviors of ovarian cancer by inhibiting MEK/ERK signaling pathway.
CircSMAD4 shapes matrix-remodeling TAMs in lung adenocarcinoma.
Mitochondrial IRF3 drives pulmonary fibrosis by impairing mitophagy and triggering ferroptosis.
INHBB promotes liver metastasis of colorectal cancer via regulation of TGF-β/Smad signaling, EMT and anoikis resistance.
GSDME Deficiency Suppresses ER Stress-Induced Autophagic Cell Death via mTOR/S6K1 Activation in Hepatobiliary Carcinomas.
PSMA-Targeting Macrophage Membrane-Coated Nanoparticles for Precision Diagnosis and Combination Therapy of Prostate Cancer.
Photobiomodulation therapy inhibits ISO-induced myocardial remodeling in mice through modulating TGF-β/Smad7 and PI3K/AKT pathways.
Angiotensin II type 1 receptor signaling promotes bladder cancer progression and its inhibition by Losartan.
Core fucosylation of NCEH1 by FUT8 promotes progression of high-grade serous ovarian cancer by driving tumor-associated macrophage M2 polarization.
Loss of TRAIP Could Attenuate the Breast Cancer Cells Development by Regulating PLSCR4 Stabilization.
CircRNA SLAIN1 is associated with reduced malignancy progression of glioblastoma and the M2-like polarization of tumor-associated macrophages via miR-1225-3p/NLRX1 axis.
Pentraxin-related protein PTX3 alleviates blast-induced acute lung injury by promoting efferocytosis to eliminate ferroptotic alveolar epithelial cells in vitro.
Mechanism of Gzma-mediated GEF-H1 activation in intestinal epithelial cells leading to intestinal barrier dysfunction in sepsis.
eIF3i facilitates NELFCD translation to promote metastasis via regulating EMT and invadopodia.
Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression.
SLC2A3-Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion.
Tumor-Associated Macrophage-Derived CXCL1 Promotes Endometrial Cancer Progression Through the CXCR2/NF-κB Pathway.
Three-dimensional patient-derived endometriosis model for drug evaluation.
Novel transcription factor zinc finger 514 suppresses lung adenocarcinoma progression and enhances cisplatin sensitivity via transcriptional repression of COL1A1.
Advanced glycation end products promote Porphyromonas gingivalis dissemination via an ROS-dependent, inflammation-independent mechanism.
O-GlcNAc Modification Orchestrates HUWE1-Mediated Ubiquitination of TfR1 to Regulate Ferroptosis and Trophoblast Syncytialization in Preeclampsia.
SIRT1-regulated mitophagy mitigates lipotoxicity-induced ferroptosis in diabetic kidney disease.
Prostaglandin E(2)-driven dedifferentiation of Schwann cells leads to perineural invasion in pancreatic ductal adenocarcinoma.
UCHL3 Promotes Triple-Negative Breast Cancer Metastatic Potential Through Enhancing Cell Migration and Invasion.
Extracellular vesicles derived from senescent hepatocytes drive pan-cancer metastasis in aging.
Discovery of indolinone-based covalent ULK1 inhibitors that suppressed autophagy and induced apoptosis against colorectal carcinoma.
A conserved re-epithelialization program underlies malignancy in pancreatic ductal adenocarcinoma.
A Biomimetic Mn-Doped Polydopamine Nanoplatform for MRI-Enabled Synergistic Therapy to Enhance Lenvatinib Efficacy in Liver Cancer.
Vitexin attenuates gastric precancerous lesions with EGFR as a potential target based on network pharmacology and molecular simulations.
Ophiopogon japonicus Polysaccharides Promote Microbial Production Of Chenodeoxycholic Acid To Alleviate Ulcerative Colitis in Mice by Inhibiting the STING1-Related NF-κB Pathway.
Targeting keratin 6 A overcomes gemcitabine resistance by restoring equilibrative nucleoside transporter 1 and TAM-mediated metabolic compensation in pancreatic cancer.
KIAA1429 promotes clear cell renal cell carcinoma progression by regulating MYC mRNA stability.
Atmospheric particulate matter impairs pulmonary barriers by triggering FTH1-mediated ferroptosis.
Curcumin Induces Macrophages Polarization to Alleviate Ulcerative Colitis by Regulating Macrophage Nuclear Morphology via Affecting the Interaction Between Enteric Glial Cells Glial-Derived Neurotrophic Factor and Casein Kinase 2.
IL-5 promotes airway remodeling in asthma by mediating epithelial-mesenchymal transition via the AKT/NLRP3 pathway.
Ginsenoside Rg3 synergizes with near-infrared photothermal therapy to suppress prostate cancer progression by inhibiting RAS signaling and enhancing ARL11-mediated macrophage reprogramming.
Phenethyl Isothiocyanate Suppresses Hepatocellular Carcinoma Progression and Immune Evasion via ZNF652 Regulation of PD-L1.
CRYM suppresses glioblastoma progression by inhibiting the TGFβ1/Smad-EMT signaling pathway.
lncRNA DLGAP1-AS2 Modulates the TGF-β/Smad Signaling Pathway to Regulate Epithelial-Mesenchymal Transition in Renal Cell Carcinoma.
VHL-recruiting PROTAC attenuates AKI-CKD transition via simultaneous degradation of Smad3 and stabilization of HIF-2α.
TRIM29 suppresses malignant progression in lung squamous cell carcinoma by shaping an immunosuppressive tumor microenvironment.
SEMA6A overexpression inhibited tumor growth and metastasis in colorectal cancer.
LTF regulates glioblastoma progression and temozolomide resistance via the NF-κB signaling pathway.
ZMIZ2/MCM3 Axis Participates in Triple-Negative Breast Cancer Progression.
CEP55 Promotes Acral Melanoma Progression via MAPK Pathway and Predicts Survival Following Immunotherapy.
CYMP-AS1 Promotes Ovarian Cancer Progression by Enhancing the Intracellular Translocation of hnRNPM and Reducing the Stability of AXIN2 mRNA.
ETV1 transcriptional manipulation of KIFC1 regulates the progression of pancreatic cancer.
Terpinen-4-ol suppresses proliferation and motility of cutaneous squamous cell carcinoma cells by enhancing calpain-2 expression.
ARPC1B Promotes Clear Cell Renal Cell Carcinoma Progression via the Wnt/β-Catenin Signaling Pathway.
Smad7 ameliorate small airway remodeling in COPD by modulating epithelial-mesenchymal transition.
Platelet-rich fibrin promotes mesothelial cell proliferation and peritoneal repair by up-regulating calretinin to prevent postoperative intestinal adhesion.
Cancer-associated Fibroblast-like Cells Promote Osteosarcoma Metastasis by Upregulation of Phosphoserine Aminotransferase 1 and Activation of the mTOR/S6K Pathway.
Identification of MAPK12 as a Prognostic Biomarker for Esophageal Carcinoma Using Bioinformatics and Machine Learning.
Targeting interferon-stimulated gene of 20 kDa protein (Isg20) inhibits ribosome biogenesis to ameliorate the progression of renal fibrosis.
Exploring the level of metabolic reprogramming and the role of prognostic factor SF3A3 in hepatocellular carcinoma through integrated single-cell landscape analysis.
Inhibition of HPSE/SDC-2 axis-induced epithelial-mesenchymal transition for treating IC/BPS.
IGF2BP2 contributes to thyroid cancer progression by enhancing the stability of m6A-modified CTSH mRNA.
AKAP12, mediated by transcription factor 21, inhibits cell proliferation, metastasis, and glycolysis in lung squamous cell carcinoma.
Exosome-Delivered circFOXP1 Upregulates Autophagy and Promotes Hepatocellular Carcinoma Progression Through Its Encoded p196 Protein Targeting the KHDRBS3/ULK1 Axis.
Mechanistic Exploration of Shugan Jianpi Formula for Treating Triple-Negative Breast Cancer Under Chronic Stress: A Network Pharmacology-Guided Experimental Study.
PTPRN promotes glioma cell proliferation, migration, and invasion by regulating the EMT pathway.
Promotion of human choroidal melanoma cell metastases by FOXP3 via Wnt5a/CaMKII signaling pathway.
Finerenone Ameliorates High Glucose-Induced Podocytes Epithelial-Mesenchymal Transition Through the Regulation of Krüppel-Like Factor 5 in Diabetic Nephropathy.
Ginsenoside Rg3 exerts anticancer effects in lung cancer through metabolite Histon H3.
MiR-124-3p inhibits proliferation, migration, and epithelial-mesenchymal transformation in gastric cancer by targeting ITGB1.
PLXND1 from the Plexins family is a prognostic factor promoting colon cancer invasion and metastasis.
As a New Tumor Suppressor Gene, PID1 Activates the AMPK-mTOR Signal to Inhibit the Progression of Bladder Cancer.
Aldose Reductase Mediated Mitophagy Promotes Epithelial-Mesenchymal Transition of Hepatocytes.
Multi-Omics Analysis Reveals the transforming growth factor-β Signaling-Driven Multicellular Interactions with Prognostic Relevance in Cervical Cancer Progression.
A novel EMT-related risk score model for Uveal melanoma based on ZNF667-AS1 and AP005121.1.
COL6A2 drives clear cell renal cell carcinoma progression via integrin-dependent modulation of Wnt/β-catenin signaling.
Comprehensive Bioinformatics Analysis and Validation of the Mechanism of Glutamic-pyruvic Transaminase 2 in Bladder Cancer.
Vericiguat attenuates cyclosporine A-induced nephropathy by targeting the NF-κB/TGF-β1 axis: an integrated network pharmacology, Mendelian randomization, and experimental study.
Cardamonin induces apoptosis of colorectal cancer cells via targeted inhibition of the JAK/STAT3/epithelial-mesenchymal transition (EMT) signaling axis.
Camel milk and fermented camel milk prevent dextran sulfate sodium-induced ulcerative colitis via the intestinal flora-short-chain fatty acids-mucosal barrier axis in mice.
R3HDM4 influences kidney renal clear cell carcinoma progression, immune modulation, and potential links to the IGSF8 immune checkpoint.
CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.
MFSD12 promotes proliferation, metastasis and invasion of hepatocellular carcinoma cells and its potential correlation with HAVCR2/LGALS9 immune checkpoint axis.
Prognostic modeling of glioma using epilepsy-related genes highlights PAX3 as a regulator of migration and vorinostat sensitivity.
circWWC3 enhances the progression of triple-negative breast cancer by interacting with vimentin to regulate the secretion of CSF2.
Multi-cohort validation based on coagulation-related genes for predicting prognosis of esophageal squamous cell carcinoma.
Thymidine kinase 1 related to Prolif-like T cells promoted GBM through regulation of cell cycle and EMT signals: a comprehensive research based on multi-omics analysis and experimental validation.
Identify GDPD3 as a key regulator of epithelial-mesenchymal transition and prostate adenocarcinoma progression via the LPA/LPAR1/AKT axis: transcriptomic and experimental study.
Reciprocal activation between M1 macrophages and trophoblasts through CXCL9/STAT1/ZEB1/CCL2 axis promotes recurrent spontaneous abortion.
Integrated analysis of single cell and spatial transcriptomics revealed a metastasis mechanism mediated by fatty acid metabolism in lymph nodes of head and neck cancer.
Quercetin ameliorates epithelial-mesenchymal transition and inflammation by targeting FSTL1 and modulating the NF-κB pathway in pulmonary fibrosis.
CPLX1 is a novel prognostic biomarker in CRC correlating with immunotherapy resistance and ferroptosis.
Landscape analysis of matrix metalloproteinases reveals key prognostic markers for prostate cancer.
Dissecting the multi-omics landscape of TEAD1 in hepatocellular carcinoma: cycle regulation and metastatic potential.
The miR-941/FOXN4/TGF-β feedback loop induces N2 polarization of neutrophils and enhances tumor progression of lung adenocarcinoma.
Prognostic significance and immune infiltration analysis of HMGA2 in endometrial cancer.
Enhancing pancreatic cancer treatment: the role of H101 oncolytic virus in irreversible electroporation.
Xanthohumol ameliorates diabetic kidney disease through suppression of renal fibrosis by regulating SNHG10/miR-378b.
A comprehensive prognostic and immunological implications of Gremlin 1 in lung adenocarcinoma.
The regulatory role of the circELMOD3-associated ceRNA network in the progression and prognosis of hepatocellular carcinoma.
Cyperotundone promotes chemosensitivity of breast cancer via SRSF1.
β-lapachone suppresses carcinogenesis of cervical cancer via interaction with AKT1.
Placental mesenchymal stem cell-derived interleukin-6 promotes neuroblastoma progression.
The ubiquitin ligase RCBTB2 regulates aggrephagy and inhibits prostate cancer progression by targeting GPAA1 for degradation.
HPV11 targeting PPARA regulates the autophagy to inhibit the occurrence and development of nasal inverted papilloma.
CMSP suppresses oral squamous cell carcinoma progression by targeting the JAK2/STAT3/c-Myc axis.
HOXB7 drives bladder cancer progression via H-Ras/ERK signaling: a potential therapeutic target and prognostic biomarker.
Securinine, a novel alkaloid, regulates cell cycle and EMT in gastric cancer by inducing iron-dependent cell death.
MEX3A is a diagnostic, independent prognostic biomarker and a promising therapeutic target in glioblastoma.
The anti-inflammatory effects of oridonin in resisting esophageal cancer.
Tricellulin facilitates colorectal cancer metastasis through activation of the TGFβ/SMAD2/3 signalling pathway.
Human annexin A5 promotes glioma progression by targeting the MAPK/CD44 pathway.
GART promotes the proliferation and migration of human non-small cell lung cancer cell lines A549 and H1299 by targeting PAICS-Akt-β-catenin pathway.
Identification and functional characterization of m1A-related genes in colorectal cancer: implications for prognosis, immune infiltration, and therapeutic strategies.
Clinical and molecular implications of sex differences in surgically treated early-onset gastric cancer.
Reduced Wiskott-Aldrich syndrome protein expression in preeclampsia placenta impairs trophoblast syncytialization by modulating syncytin-2 via FAK/β-catenin pathway.
Integrative pan-cancer analysis of UCP family and experimental validation identifies UCP2 as a potential therapeutic target for glioma.
Engineering a 3D wounded skin equivalent to study early inflammatory and regenerative responses in vitro.
Synchronous neuroendocrine tumor and signet ring cell carcinoma in the stomach: a case report and review of literature.
Ciprofol exerts anti-tumour effects in hepatocellular carcinoma through the Raf-MEK-ERK signalling pathway.
Phytochemical nanozymes reprogram redox for balanced antimicrobial and regenerative therapy in acute and chronic diabetic wounds.
PLEKHF1 Induces Mitochondrial Dysfunction to Inhibit Osteosarcoma Growth and Metastasis.
Targeting Dlat-Trpv3 pathway by hyperforin elicits non-canonical promotion of adipose thermogenesis as an effective anti-obesity strategy.
EIF3B‑METTL3 complex promotes cell proliferation, invasion and EGFR/AKT signaling in cervical cancer.
Kaempferol Suppresses Mesothelial-Mesenchymal Transition and Attenuates Postoperative Peritoneal Adhesions by Blocking the TNF-α/COX2 Signalling Pathway.
Gallium maltolate and cisplatin co-treatment effectively targets triple-negative breast cancer in spheroid and mouse models.
Study of the Reciprocal Interaction Between Tumor Cells and Macrophages Based on the Biomimic Microfluidic Device.
METTL3 Mediates Wnt/β-Catenin Pathway in Epithelial-Mesenchymal Transition of 16HBE Cells Induced by Beryllium Sulphate.
Leukemia Inhibitory Factor via JAK-STAT Signaling Drives Beryllium Sulfate-Induced Epithelial-Mesenchymal Transition in 16HBE Cells.
Up-regulation of NGEF via the BRAF(V600E) /ERK/AP1 pathway enhances invasion and migration abilities of BRAF(V600E)-mutant thyroid cancer.
Mechanism of SC targeting RhoA regulation and its potential value in gastric cancer therapy.
p62/SQSTM1 impairs immunotherapy in lung adenocarcinoma by suppressing immune infiltration and peripheral immune response.
SPOCK2 promotes the invasion and migration of ovarian cancer cells through FAK signaling pathway.
Tumor-derived exosome-based microRNA-206 delivery system as dual modulators of the immune microenvironment and gut microbiota for colorectal cancer therapy.
20-Acetylsinularolide B (ASB) From Lobophytum crassum Exhibits Anticancer Activity In Vitro Through IGF1R/PI3K/AKT/mTOR Pathway.
Chronic exposure to B[a]P induces malignant transformation of breast epithelial cells through the mechanism via TGF-β signaling pathway.
Ganoderic acid T, a novel activator of pyruvate carboxylase, exhibits potent anti-liver cancer activity.
Shenling Tongqiao powder targets TGF-β1/Smad-Wnt/β-catenin axis to suppress epithelial-mesenchymal transition in chronic rhinosinusitis.
Ginger-processed Magnoliae Officinalis Cortex ameliorates ovalbumin-induced asthma by alleviating inflammation via the gut-lung axis.
Peptide-Enhanced Bioactive Hydrogel Combined with Photodynamic-Phage Synergistic Antibacterial Therapy System Accelerates Infected Wound Healing.
Zinc Alleviates Gut Barrier Dysfunction by Promoting the Methylation of AKT.
Suppressed autophagy of thymic cells promotes apoptosis and thymic atrophy in COPD.
A Novel Nuclear-Localized Micropeptide, MP60, Promotes Hepatocellular Carcinoma Progression via the Epithelial-Mesenchymal Transition.
Lithocholic acid ameliorates ulcerative colitis via the PXR/TLR4/NF-κB/NLRP3 signaling pathway and gut microbiota modulation.
LncRNA LOXL1-AS1 promotes ovarian cancer progression by enhanced BRIP1 mRNA stability.
Development of Primary Colon and Duodenal Tumor Cultures from the Apc-mutant Pirc Rat for Screening Preventive Agents.
NRF2 promotes the migration of ovarian cancer cell lines by targeting TAGLN mediated epithelial-mesenchymal transition.
Circular RNA hsa_circ_0006522 correlates with unfavorable prognosis and promotes the proliferative, migrative, and invasive abilities of breast cancer cells.
C1orf116 inhibits acquired resistance to EGFR inhibitors in EGFR mutant lung adenocarcinoma by suppressing the ATM/ATR pathways.
CHD4 drives gastric cancer metastasis via MYH9/GSK3β/β-catenin axis and WNT/EMT pathway activation.
LCN2-positive alveolar type II cells promote silica-induced pulmonary fibrosis via STAT3-TGF-β1-Smad3-mediated signaling.
Overexpression of alcohol dehydrogenase 1 A inhibits the progress of triple negative breast cancer via Wnt/β-catenin signaling.
EMB is essential for enteric nervous system development mediated by PI3K signaling.
TAIII Suppresses the Growth of T790M-Mutant Non-Small-Cell Lung Cancer by Targeting the EGFR/ERK Signaling Pathway.
JMJD6-driven epigenetic activation of COL4A2 reprograms glioblastoma vascularization via integrin α1β1-dependent PI3K/MAPK signaling.
Orthosteric-allosteric dual inhibitors of PI5P4Kγ with potent antitumor activity in non-small cell lung cancer.
Caspase-9 activates β-catenin signaling to promote pulmonary fibrosis.
Biphasic Adaptations of Gastric Epithelial Cells in Chronic H. pylori Infection from Stress to Tolerance.
Downregulation of HDAC9 Alleviates Autophagy Dysfunction by Inducing Acetylation of ATG4B in Metabolic Dysfunction-Associated Steatotic Liver Disease.
Zearalenone at environmental levels promoted ER- positive breast cancer cell lines through the hedgehog pathway.
Inhibition of GRK2 mitigates renal fibrosis via oxidative stress pathway.
CENPA-driven transcriptional activation of ECT2 enhances EGFR inhibitor resistance in lung adenocarcinoma.
NudCL2 suppresses pancreatic cancer progression by inhibiting SLC7A11-mediated EMT and metastasis.
Dietary addition of magnesium hydride nanoparticles: a breakthrough in combating high-fat diet-induced chronic kidney disease.
TKT regulates the pentose phosphate pathway via RBKS to promote epithelial-mesenchymal transition during AML progression.
Inhibition of SLC3A2 Deletion-Mediated Ferroptosis by Bone Marrow Stromal Cells to Alleviate Inflammation and Fibrosis in Diabetic Kidney Disease.
Dapagliflozin ameliorates high glucose-induced epithelial-mesenchymal transition via up-regulating ACE2 mediated by EZH2 in diabetic nephropathy.
LGI3 promotes the progression of TFE3-rearranged renal cell carcinoma through GEMIN6/AURKB axis.
Kaempferide Inhibits the Proliferation and Invasion and Induces Ferroptosis in Melanoma by Inactivating Wnt/β-Catenin Pathway.
Resveratrol glycoside inhibits NLRP3/IL-1β/NF-κB to alleviate peritoneal fibrosis in peritoneal dialysis.
Profibrotic impact of PAD4-driven macrophage extracellular traps in ulcerative colitis.
Phosphodiesterase 12 facilitates the growth and metastatic capabilities of gastric cancer cells by activating the TCAF2/JAK2/STAT3 axis.
Small proline-rich protein 2A drives epithelial remodeling in eosinophilic chronic rhinosinusitis with nasal polyps via SAA2 upregulation.
KIF18B drives the malignant progression of gliomas by activating the Notch pathway.
Glucose Deprivation-Induced Disulfidptosis via the SLC7A11-INF2 Axis: Pan-Cancer Prognostic Exploration and Therapeutic Validation.
Discovery of Natural Compound α-Hederin via Large-Scale Screening as a Targeted JAK/STAT3 Inhibitor for Ovarian Cancer Therapy.
Hsa_circ_0005325 Regulates the Proliferation, Apoptosis, Colony Formation, Migration, and Angiogenesis-Promoting Behavior of Oral Squamous Cell Carcinoma Cells Through the miR-433-3p/HMGA2 Axis.
Geniposide alleviates kidney fibrosis by targeting STAT3-HK2-mediated glycolysis.
Oncogenic Role of SAMD4B in Breast Cancer Progression by Activating Wnt/β-Catenin Pathway.
Hypermethylation-mediated HNF4A silencing by Helicobacter pylori infection drives gastric cancer by disrupting epithelial cell polarity and activating EMT signaling.
KAT2A-H3K79succ-Mediated SH2B3 Upregulation Promotes TNBC Metastasis Through Diminishing the Ubiquitin-Dependent Degradation of Vimentin.
miR-196a-5p promotes the proliferation, migration, and invasion of esophageal squamous cell carcinoma by targeting LIFR.
FUT8 promotes HDM-induced glycolysis, epithelial-mesenchymal transition and inflammation in bronchial epithelial cells by inducing N-glycosylation modification of GLUT1.
RPL22L1-Myc positive feedback loop drives lung adenocarcinoma progression.
α-hederin inhibits cervical cancer progression by inducing DNA damage-dependent cell cycle blockade and apoptosis.
Sorcin regulates alveolarization and airway tissue remodeling during lung morphogenesis.
Macrophage-derived exosomes carrying miR-30a-5p alleviates IL-13/IL4-induced epithelial-mesenchymal transition in mouse bronchial epithelial cells via Runx1.
Fusobacterium nucleatum increases CTGF expression through TLR2-YAP signaling axis in cancer-associated fibroblasts, thereby promoting colorectal cancer progression.
Mesenchymal stem cells inhibit mitochondrial fission by upregulating armadillo repeat containing 1, ameliorating oxidative stress in renal fibrosis.
The deubiquitination enzyme USP14 promotes the tumourigenesis of gastric cancer by enhancing c-MYC nuclear translocation through deubiquitination of KPNA2.
Pan-cancer analysis of role of LOXL4 and experiment validation in osteosarcoma.
PTPN2 acts as a tumor suppressor and therapeutic target in ovarian cancer.
A Cell-Potent Bisubstrate Inhibitor to Probe NatD Acetyltransferase Activity.
Functional metabolomics revealed pyroglutamic acid may play a key role in idiopathic pulmonary fibrosis.
Nephroprotective mechanism of Kunkui Baoshen decoction in diabetic kidney disease: Targeting the HERC2/NCOA4-mediated autophagy-dependent ferroptosis pathway.
PDLIM4 drives gastric cancer malignant progression and cisplatin resistance by inhibiting HSP70 ubiquitination and degradation via competitive interaction with STUB1.
Cedrol impedes lung cancer metastasis by reducing tumor-associated macrophage polarization mediated by MYC-driven aerobic glycolysis.
Cigarette smoke extract promotes metastasis and oxaliplatin resistance in colon adenocarcinoma through GDF15/ERBB2/AKT pathway.
Centromere protein I facilitates breast cancer tumorigenesis and disease progression through modulation of Wnt/β-Catenin signaling.
Mechanism of silica nanoparticles induced pulmonary epithelial-mesenchymal transition mediated by exosomal HNRNPAB.
PARP1 promoter hypermethylation promotes arsenic-induced skin damage by driving telomere dysfunction-mediated keratinocyte senescence.
AHCTF1 Functions as an Oncogenic Factor and Promotes Tumor Progression in Hepatocellular Carcinoma.
Harnessing TP73‑targeted nintedanib: A novel strategy to halt triple‑negative breast cancer via p53‑PPARα/PI3K‑Akt pathway suppression.
EHBMT, a method for visualizing tumor evolution, identifies a surge in gastric cancer with hybrid epithelial-mesenchymal phenotypes due to an inflammatory microenvironment.
Mitochondrial dysfunction-associated cellular senescence is partially involved in bleomycin-induced pulmonary fibrosis in mice.
METTL16 promotes progression of clear cell renal cell carcinoma via up-regulating N6-methyladenosine modification of KLK4 mRNA.
Astragaloside IV Alleviates Cisplatin Chemotherapy-Induced Nephrotoxicity via Modulation of Nrf2/HO-1/NF-κB Pathway and Reversal of EMT Process.
Integrative multi-omics analysis and experimental validation reveal centromere protein W as a potential therapeutic target and predictive biomarker in renal clear cell carcinoma.
Targeting MTPN sensitizes pancreatic cancer of wild-type BRCA1/2 to Cisplatin-based chemotherapy.
Galectin-9 promotes colon cancer development by polarizing macrophages toward the M2 phenotype.
METTL3/IGF2BP2 stabilizes IQGAP3 via m6A modification to drive HCC metastasis through TGF-β/Smad signaling and EMT.
UBE2O-mediated ubiquitylation directs cytoplasmic CTNNA1 to promote cell-to-ECM adhesions.
A Shikonin Derivative Induces Excessive Autophagy in Pancreatic Cancer Cells.
TRIB3 promotes endometrial cancer progression through interacting with E2F1 and enhancing PKM2-mediated tumor glycolysis.
Identification and validation of BCL11A as a neural and immune vulnerability factor in pancreatic adenocarcinoma.
A novel off-liver sinusoidal progenitor cells in supporting transplantable bioliver engineering.
Protective role of orphan G protein-coupled receptor GPR35 in the pathogenesis of colitis through regulating epithelial barrier function and immune responses.
Rosmarinic acid induces ferroptosis in colon cancer: insights from AKR1C3/PTGS2 pathway and mitochondrial dysfunction.
MicroRNA-93-5p alleviates uric acid-induced fibrosis in renal tubular epithelial cells by regulating the SMAD5/Id2 signaling pathway.
N-glycosylation stabilized TNFAIP6 promotes ovarian cancer metastasis by activating the PI3K-AKT signaling pathway.
CX-5461 inhibits cell proliferation and induces ferroptosis of colorectal cancer cells by inactivating Nrf2 pathway.
The E3 ubiquitin ligase TRIM31 enhances the progression of esophageal cancer through the ubiquitination of BBOX1.
Aberrant PJA2-CHRM3 signaling creates a therapeutic vulnerability in gastric tumor.
RAB26 promotes prostate cancer progression via the MAPK/ERK-TWIST1 signaling axis.
Multi-Omics and Molecular Dynamics Analysis for Biomarker Discovery in Chronic Rhinosinusitis With Nasal Polyps.
Effects of fibroblasts-derived exosomal FAP in regulating EMT in epithelial cells from chronic rhinosinusitis.
P2Y6 receptor inhibition arrests tumor cell progression in a mouse lymphoma model.
Genome edited intestine liver on a chip system for integrated intestinal hepatic drug absorption and metabolism evaluation.
Ly96-mediated activation of TGF-β1/Smad2/3 signaling in hepatocellular carcinoma and its potential for nanoparticle-based therapy.
Dapagliflozin ameliorates high glucose-induced peritoneal fibrosis through downregulation of ENKUR/PI3K/AKT signaling pathway.
Aucubin inhibits the activity of lung cancer stem-like cells by targeting degradation of β-catenin.
RTA-408 Enhances Radiosensitivity and Inhibited Tumor Progression via JNK Pathway in Glioblastoma.
HCAR2 inhibits prostate cancer invasion and metastasis by regulating cAMP signaling pathway.
hsa_circ_0135681 functions as a novel tumor-suppressive circular RNA regulating Glycolysis and EMT to attenuate cisplatin resistance in non-small cell lung cancer.
GLMP promotes EGFR-TKI resistance by activating autophagy and RhoA pathway in non-small cell lung cancer.
Protein kinase D2-mediated maintenance complex component 2 phosphorylation promotes bladder cancer progression.
CAFs-derived SPI1 in tumor fibroblasts promotes malignant behaviors of liver cancer cells and immune escape by regulating HRAS and PD-L1 transcription.
Sec14L6 is a phosphoinositide transporter that regulates phosphoinositide homeostasis and biogenesis of lipid droplets.
Jianpi Huayu decoction exerts antitumor effects in pancreatic cancer via SCD1-mediated lipid metabolism remodeling/ferroptosis axis.
Zhilining formula alleviates ulcerative colitis by restricting STAT3 activation and subsequent Th17 cell differentiation.
Anti-tumor effects of Cinnamomum camphora essential oil in breast cancer via NOX4 modulation by (+)-2-bornanone.
Ferulic acid ameliorates TLR4-mediated macrophage activation by irreversibly binding to peroxiredoxin 1 to inhibit its dimerization and secretion.
Silencing Clusterin Could Attenuate the Cell Properties of HCV Core Protein-Expressing HCC Cell Line.
Dynamic remodelling of epithelial plasticity in colorectal cancer from single-cell and spatially resolved perspectives.
Keratin 80 serves as a potential biomarker in metastatic breast cancer.
RBMX2 links Mycobacterium bovis infection to epithelial-mesenchymal transition and lung cancer progression.
BNC2 as a novel driver of pancreatic cancer progression through transcriptional regulation of COL3A1 and epithelial-to-mesenchymal transition.
ZIC5, a survival biomarker, facilitates tumor progression and stemness in colon cancer via the activation of the Wnt signaling pathway.
HMGA1 drives EMT in obliterative bronchiolitis through epigenetic regulation of chromatin accessibility in pulmonary epithelial cells.
Novel bakuchiol derivatives inhibit the migration and invasion of non-small cell lung cancer by suppressing epithelial-to-mesenchymal transition.
Influenza a(H1N1) virus infection impairs syncytiotrophoblast functions by promoting ferroptosis through the TNF-α/ISG15/EGR1 axis.
Ozone aging amplifies the tumor-promoting effects associated with low-dose graphene oxide exposure in bladder tumors via the integrin αV signaling pathway.
Antimony exposure induces bladder cancer metastasis via activation of the SUMOylation-dependent TGF-β/Smad2/3 axis.
Therapeutic potential of the LUCAT1/miR- 2278/STAT5A axis in pulmonary fibrosis.
Curcumenol exerts anti-pulmonary fibrosis effects through modulation of the immune signature target SPP1: based on comprehensive bioinformatics and experiments validation.
MiR-5095 inhibits proliferation, migration, and invasion of gastric cancer cells by targeting CEACAM5.
S100 Calcium-Binding Protein P and Cathepsin E as Key Mediators in Pancreatic Cancer Tumorigenesis.
AARS1 promotes endometriosis progression by promoting the lactylation of Snail1†.
Ginsenoside Rh2 as a novel PIN1 inhibitor disrupting the cancer stem cell-like phenotype in non-small cell lung cancer.
A PCD-related prognostic signature and the oncogenic role of TRIM8 in osteosarcoma progression.
Optimized inner ear organoids for efficient hair cell generation and ototoxicity response modeling.
Overexpression of PLK1 Molecule Following Incomplete Thermal Ablation Promotes the Proliferation and Invasion of Residual Hepatocellular Carcinoma.
The efficacy and underlying mechanisms of berberine in the treatment of recurrent Clostridioides difficile infection.
Single-cell and spatial RNA sequencing identify divergent microenvironments and progression signatures in early- versus late-onset prostate cancer.
KMT2A facilitates the epithelial-to-mesenchymal transition and the progression of ovarian cancer.
PRSS23-eIF4E-c-Myc axis promotes gastric tumorigenesis and progression.
Protective effects of jiawei yupingfeng polysaccharides on cyclophosphamide-induced intestinal injury in mice.
An exploration on the involvement of the methyltransferase like 3-m(6)A‑zinc finger MYM-type containing 1 axis in the progression of liver hepatocellular carcinoma.
METTL3-mediated m6A modification of PAK6 drives cervical cancer progression through activating MAPK14.
HKDC1 promotes colorectal cancer progression by regulating RCOR1 expression to activate the Wnt/β-catenin pathway, enhancing proliferation, migration, and epithelial-mesenchymal transition.
A novel 5-differentially expressed gene (DEG) signature predicting the prognosis in patients with metastatic liver malignancies and the prognostic and therapeutic potential of SPP1.
Kv1.3 expression on CD4 (+) T cells promotes interleukin-17A-associated airway inflammation and airway remodeling in asthma.
PTPRG-AS1 regulates the KITLG/KIT pathway through the ceRNA axis to promote the malignant progression of gastric cancer and the intervention effect of Compound Kushen injection on it.
CHPF2 as a novel biomarker and ponicidin as a potential therapeutic agent in hepatocellular carcinoma.
Circular RNA ATP9A Stimulates Non-small Cell Lung Cancer Progression via MicroRNA-582-3p/Ribosomal Protein Large P0 Axis and Activating Phosphatidylinositol 3-Kinase/Protein Kinase B Signaling Pathway.
EFNA2 Mediates Stiffness-Regulated Hypopharyngeal Cancer Progression.
Jiawei Danxuan Koukang and its key component Quercetin intervened in OSF carcinogenesis by inhibiting the AR/eIF5A2 signaling pathway-mediated EMT.
EGFR-mediated crosstalk between vascular endothelial cells and hepatocytes promotes Piezo1-dependent liver regeneration.
From Invaginating Site to Deep Lesion: Spatial Transcriptomics Unravels Ectopic Endometrial Penetration Features in Adenomyosis.
Novel Phenoxyacetic Acid (4-Aminophenoacetic Acid) Shikonin Ester Kills KRAS Mutant Colon Cancer Cells via Targeting the Akt Allosteric Site.
Artesunate Enhances Sensitivity of Renal Cancer Cells to Sunitnib by Mediating Tripartite Motif Containing 24-Induced Ubiquitination of Paired Box 6.
Metabolic-associated fatty liver disease (MAFLD) promotes the progression of hepatocellular carcinoma by enhancing KIF20A expression.
Integrated Analysis of Disulfidptosis-Related Genes Identifies CD2AP as a Potential Therapeutic Target for Hepatocellular Carcinoma.
The high expression of Long noncoding RNA TEX41 promotes the proliferation, migration, and invasion of hepatocellular carcinoma.
The lncRNA MIR22HG suppresses prostate cancer cell proliferation, migration, and epithelial-mesenchymal transition via the miR-4428/PCDH9 axis.
Enhanced mitochondrial biogenesis facilitates the development of cutaneous squamous cell carcinoma.
Metabolite-dependent m(6)A methylation driven by mechanotransduction-metabolism-epitranscriptomics axis promotes bone development and regeneration.
SPINT1 Expressed in Epithelial Cells of Choroid Plexus in Human and Mouse Brains.
Enhanced anti-cancer effect of AMTB hydrochloride via chitosan nanoparticles in pancreatic cancer.
GP73-dependent regulation of exosome biogenesis promotes colorectal cancer liver metastasis.
Cinobufagin inhibits hepatocellular carcinoma EMT-like stemness via VEGF/VEGFR2 autocrine signaling.
The Therapeutic Potential of Bombyx Batryticatus for Chronic Atrophic Gastritis Precancerous Lesions via the PI3K/AKT/mTOR Pathway Based on Network Pharmacology of Blood-Entering Components.
MiR-493-5p functions as a tumour suppressor in head and neck squamous cell carcinoma progression by targeting HIF-1α.
miRNA-1229-5p promotes migration and invasion and suppresses apoptosis of endometrial cells via the STMN1/p38 MAPK axis in endometriosis.
GALR1 and PENK serve as potential biomarkers in invasive non-functional pituitary neuroendocrine tumours.
A dual-targeting bio-liposomes nanodrug repair endothelial cell dysfunction and restore macrophage cholesterol flow homeostasis to treat early atherosclerosis.
TMBIM1 promotes epithelial mesenchymal transition by accelerating autophagic degradation of E-cadherin in glioblastoma.
Fibrogenesis-driven tumor progression in clear cell renal cell carcinoma: prognostic, therapeutic implications and the dual role of neuropilin-1.
Piezo1 regulates actin cytoskeleton remodeling to drive EMT in cervical cancer through the RhoA/ROCK1/PIP2 signaling pathway.
Bufei Yishen formula alleviates airway epithelial cell senescence in COPD by activating AMPK-Sirt1-FoxO3a pathway and promoting autophagy.
CPT1A/HIF-1α positive feedback loop induced fatty acid oxidation metabolic pathway contributes to the L-ascorbic acid-driven angiogenesis in breast cancer.
A novel scheme for non-invasive drug delivery with a magnetically controlled drug delivering capsule endoscope.
A novel lncRNA ABCE1-5 regulates pulmonary fibrosis by targeting KRT14.
Knowledge-guided multi-level network modeling with experimental characterization identifies PRKCA as a novel biomarker and tumor suppressor triggering ferroptosis in prostate cancer.
Depletion of Acetyl-CoA Carboxylase 1 Facilitates Epithelial-Mesenchymal Transition in Prostate Cancer Cells by Activating the MAPK/ERK Pathway.
Targeting ADAR1 with a small molecule for the treatment of prostate cancer.
Research on LCN2 interference to enhance the sensitivity of drug-resistant strains to gemcitabine.
Cellular heterogeneity and communication networks in gastric cancer: Single-cell analysis reveals β-hydroxybutyrylation-associated genes and immune infiltration characteristics.
Breast cancer stem cell-derived exosomal lnc-PDGFD induces fibroblast-niche formation and promotes lung metastasis.
Bergapten Ameliorates Renal Fibrosis by Inhibiting Ferroptosis.
UBE2Q1 as a novel cancer biomarker for lung adenocarcinoma.
The role of Collagen Tissue Scaffolds in 3D Endometrial-like Culture Systems: Important Contributions to Cell Invasion and Cell Topography.
FXYD5 regulates gastric cancer cell metastasis and drug resistance by EMT modulation.
USP1 promotes pancreatic cancer progression and autophagy by deubiquitinating ATG14.
The MCM6-c-Myc positive feedback loop mediates bladder cancer progression and cisplatin resistance.
Chemerin's Role in Endometrial Dysfunction: Insights From Transcriptomic Analysis.
DDR1 Targeting HOXA6 Facilitates Bladder Cancer Progression via Inhibiting Ferroptosis.
Ubiquitin-specific peptidase 10 promotes renal interstitial fibrosis progression through deubiquitinating and stabilizing P53 protein.
High MICAL-L2 promotes cancer progression and drug resistance in renal clear cell carcinoma cells through stabilization of ACTN4 following vimentin expression.
β-eudesmol inhibits cell growth and enhances cell chemosensitivity of NPC through targeting FGF1/FGFR signaling.
circTUBD1-hnRNPK Regulates the Proliferation and Migration of LSCC by Targeting CCAR1.
SSBP1 positively regulates RRM2, affecting epithelial mesenchymal transition and cell cycle arrest in human lung adenocarcinoma cells.
Excessive MYC Orchestrates Macrophages induced Chromatin Remodeling to Sustain Micropapillary-Patterned Malignancy in Lung Adenocarcinoma.
Intestine-Decipher Engineered Capsules Protect Against Sepsis-induced Intestinal Injury via Broad-spectrum Anti-inflammation and Parthanatos Inhibition.
MLLT3 Regulates Melanoma Stemness and Progression by Inhibiting HMGB1 Nuclear Entry and MAGEA1 M(5)C Modification.
Silencing long non-coding RNA linc00689 suppresses the growth and invasion of osteosarcoma cells by targeting miR-129-5p/NUSAP1.
Melatonin affects trophoblast epithelial-to-mesenchymal transition and oxidative damage resistance by modulating GDF15 expression to promote embryo implantation.
HNRNPC promotes progression of non-small cell lung cancer by maintaining TFAP2A mRNA stability.
Parvimonas micra promotes oral squamous cell carcinoma metastasis through TmpC-CKAP4 axis.
Semaglutide, a glucagon-like peptide-1 receptor agonist, inhibits oral squamous cell carcinoma growth through P38 MAPK signaling pathway.
cGAS-STING mediates neutrophil extracellular traps-induced EMT in myositis-associated interstitial lung disease: STING as a potential therapeutic target.
Inhibition of NLRP3 alleviates calcium oxalate crystal-induced renal fibrosis and crystal adhesion.
c-Jun promotes neuroblastoma cell differentiation by inhibiting APC formation via CDC16 and reduces neuroblastoma malignancy.
miR-378d suppresses gastric cancer metastasis by targeting METTL4 to inhibit epithelial-mesenchymal transition.
Protocol for generating brain metastatic tumor cells through repeated intracardiac injections in mice.
Single-molecule m(6)A detection empowered by endogenous labeling unveils complexities across RNA isoforms.
Rare and common genetic variants underlying the risk of Hirschsprung's disease.
Isoliquiritigenin attenuates tumor progression and PD-L1 expression by inhibiting the phosphorylation of STAT3 in melanoma.
TMEM176B inhibits ovarian cancer progression by regulating EMT via the Wnt/β-catenin signaling pathway.
Sterically chained amino acid-rich water-soluble carbon quantum dots as a robust tumor-targeted drug delivery platform.
Chlorogenic acid induces hepatocellular carcinoma cell ferroptosis via PTGS2/AKR1C3/GPX4 axis-mediated reprogramming of arachidonic acid metabolism.
Transmembrane protein 176B promotes epithelial-mesenchymal transition in colorectal cancer through inflammasome inhibition.
Crip2 affects vascular development by fine-tuning endothelial cell aggregation and proliferation.
Starvation-induced HBP metabolic reprogramming and STAM2 O-GlcNAcylation facilitate bladder cancer metastasis.
The feedback loop between miR-222-3p and ZEB1 harnesses metastasis in renal cell carcinoma.
RBM10 deficiency promotes brain metastasis by modulating sphingolipid metabolism in a BBB model of EGFR mutant lung adenocarcinoma.
Ginsenoside Rh4 inhibits colorectal cancer via the modulation of gut microbiota-mediated bile acid metabolism.
miR-135b-5p/PDE3B Axis Regulates Gemcitabine Resistance in Pancreatic Cancer Through Epithelial-Mesenchymal Transition.
Granzyme B Promotes Proliferation, Migration and EMT Process in Gastric Cancer.
Identification and Validation of Basement Membrane Related LncRNA Signatures as a Novel Prognostic Model for Hepatocellular Carcinoma.
Cancer-associated fibroblasts promote growth and dissemination of esophageal squamous cell carcinoma cells by secreting WNT family member 5A.
Metformin Attenuates Partial Epithelial-Mesenchymal Transition in Salivary Gland Inflammation via PI3K/Akt/GSK3β/Snail Signaling Axis.
Effects of the S1P/S1PR1 Signaling Pathway on High Glucose-Induced NRK-52E Epithelial-Mesenchymal Transition Via Regulation of ROS/NLRP3.
LncRNA MKLN1-AS promotes glioma tumorigenesis and growth via activating the Hippo pathway through miR-126-5p/TEAD1 axis.
Glycated ECM Derived Carbon Dots Inhibit Tumor Vasculogenic Mimicry by Disrupting RAGE Nuclear Translocation and Its Interaction With HMGB1.
Bioinspired hydrogel for sustained minocycline release: A superior periodontitis solution.
Establishment of Long-Term Expansion Culture for Primary Murine Nasopharyngeal Cells.
GJB2 as a novel prognostic biomarker associated with immune infiltration and cuproptosis in ovarian cancer.
Mechanistic study of Liquiritigenin inhibiting bladder cancer cell proliferation and migration by regulating STING1.
Hippo Pathway Regulates Cell Proliferation in Skin Epidermis Exposed to Mechanical Forces.
LncRNA SNHG14 Regulated by ZNF460 Promotes Gastric Cancer Progression and Metastasis by Targeting the miR-206/FNDC3A Axis.
Charge-reversed small extracellular vesicles from human adipose-derived mesenchymal stromal cells attenuate renal fibrosis postacute kidney injury by inhibiting epithelial-mesenchymal transition progression in SD rat model.
Rotenone adaptation promotes migration and invasion of p53-wild-type colon cancer through lipid metabolism.
Resveratrol interrupts Wnt/β-catenin signalling in cervical cancer by activating ten-eleven translocation 5-methylcytosine dioxygenase 1.
MBD2 promotes epithelial-to-mesenchymal transition (EMT) and ARDS-related pulmonary fibrosis by modulating FZD2.
LncRNA MIR503HG regulates NETs-mediated NLRP3 inflammasome activation and NSCLC metastasis by enhancing the ubiquitination of C/EBPβ.
Huang-Lian-Jie-Du decoction inhibits CD4+ T cell infiltration into CNS in MCAO rats by regulating BBB.
EFNA1 promotes the tumorigenesis and metastasis of cervical cancer by phosphorylation pathway and epithelial-mesenchymal transition.
The JAK1/STAT3 pathway mediates the effects of SERPINH1 on glioma EMT.
TSP50 deficiency in neural stem cells aggravates colitis in mice by altering intestinal microbiome.
Oleanolic Acid Restores Drug Sensitivity in Sorafenib-resistant Hepatocellular Carcinoma: Evidence from In Vitro and In Vivo Studies.
Compound kushen injection inhibits breast cancer lung metastasis through regulating MTSS1/ARPC3/F-actin.
The activation of cGAS-STING pathway promotes the epithelial-mesenchymal transition and inflammation in intrauterine adhesion.
Dexmedetomidine promotes colorectal cancer progression mediated by gamma-aminobutyric acid signaling.
IGFBP2 Modulates Trophoblast Function and Epithelial-Mesenchymal Transition in Preeclampsia via the PI3K/AKT Signaling Pathway.
DDX5 super-enhancer promotes vasculogenic mimicry formation and metastasis in nasopharyngeal carcinoma by enhancing ADAM10 transcription.
Polystyrene nanoplastics aggravate house dust mite induced allergic airway inflammation through EGFR/ERK-dependent lung epithelial barrier dysfunction.
Mechanism of trypsin-mediated differentiation of pancreatic progenitor cells into functional islet-like clusters.
Taraxacum mongolicum total triterpenoids and taraxasterol ameliorate benign prostatic hyperplasia by inhibiting androgen levels, inflammatory responses, and epithelial-mesenchymal transition via the TGFβ1/Smad signalling pathway.
Nobiletin from Citrus reticulata Blanco alleviates pulmonary fibrosis through inhibiting the PI3K/AKT pathway and epithelial-mesenchymal transition.
PDGFC secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and immunosuppression in lung adenocarcinoma.
Targeted Knockdown of Epithelial Estrogen Receptor α to Mitigate Ferroptosis and Epithelial-Mesenchymal Transition in Eosinophilic Asthma.
Role of the USP7/FOXO3A axis in environmentally relevant doses of arsenic-induced lung carcinogenesis: Insights from bioinformatics analysis and model of human epithelial cell malignant transformation.
Curcumenol inhibits malignant progression and promotes ferroptosis via the SLC7A11/NF‑κB/TGF‑β pathway in triple‑negative breast cancer.
CYP2A6 suppresses hepatocellular carcinoma via inhibiting SRC/Wnt/β-Catenin pathway.
SERPINB6 Promotes Epithelial-Mesenchymal Transition via PI3K/AKT/mTOR Signalling Pathway in Glioma.
HucMSC-Ex alleviates inflammatory bowel disease by regulating O-GlcNAcylation modification of RACK1 in intestinal epithelial cells.
Increased SUMO-activating enzyme subunit 1 promotes glycolysis and fibrotic phenotype of diabetic nephropathy.
Wenxia Changfu Formula inhibits NSCLC metastasis by halting TAMs-induced epithelial-mesenchymal transition via antagonisticallymodulating CCL18.
Nanoplastics Chronic Toxicity in Mice: Disturbing the Homeostasis of Tryptophan Metabolism in Gut-Lung-Microbiota Axis.
A-485 alleviates fibrosis and apoptosis in kidney by disrupting tandem activation of acetylation and phosphorylation on STAT3.
Identification of the Oncogenic Role of MSH2 in the Stemness and Progression of Glioma Through Regulating Wnt Signaling Pathway.
Neoadjuvant Chemotherapy With Cisplatin Up-Regulates GSDMD to Enhance Oral Squamous Cell Carcinoma Metastasis Through MMP14-Mediated EMT Activation.
LncRNA small nucleolar RNA host gene 1 (SNHG1) mediates acidic bile salt-induced EMT via the ULK1-Notch1 axis in Barrett's esophagus.
Synergistic antitumor effects and mechanistic insight of hypericin-mediated photodynamic therapy combined with Olaparib in MCF-7 BRCA1 wild-type breast cancer cells.
M6A-Methylated circRAPGEF5 drives lung adenocarcinoma progression and metastasis via IGF2BP2/NUP160-mediated autophagy suppression.
P300-dependent acetylation of the FOXQ1 complex activates super-enhancers to promote colorectal cancer proliferation and metastasis.
Disintegrin Rhodostomin Mutant Ameliorates the Severity of Experimental Proliferative Vitreoretinopathy by Suppressing Both Integrin αvβ3 and α5β1.
Bovine lactoferrin drives cell cycle arrest and alters the transcriptomic profile of NSCLC cells.
RhoJ promotes the progression of clear cell renal cell carcinoma via the TNF-α/NF-κB axis.
Establishing dorsal-ventral patterning in human neural tube organoids with synthetic organizers.
The value of acetylation reader YEATS2 in hepatocellular carcinoma management.
CRP and HNF1A collaborate to regulate the progression of laryngeal cancer through the Wnt signaling pathway.
GPX3 promotes cisplatin resistance in TNBC by manipulating ROS-TGFB1-ZEB2.
Engineered tumor microspheres via microfluidics and decellularized extracellular matrix for high-throughput organoid-based drug screening.
Terrestrosin D promotes autophagy and apoptosis of breast cancer cells through PSMD1-dependent activation of P53 pathway.
Curzerene suppresses epithelial-mesenchymal transition in gastric precancerous lesion cells through targeted regulation of YAP via the long non-coding RNA AFAP1-AS1.
Qingshu Yiqi decoction ameliorates exertional heat stroke-induced intestinal barrier injury via NF-κB/MLC pathway and gut microbiota.
EphrinB2 alleviates tubulointerstitial fibrosis in diabetic kidney disease.
Phosphodiesterase 1A physically interacts with YTHDF2 and reinforces the progression of non-small cell lung cancer.
Growth Hormone Signaling in Bladder Cancer: Transcriptomic Profiling of Patient Samples and In Vitro Evidence of Therapy Resistance via ABC Transporters and EMT Activation.
DSS1 inhibits autophagy to activate epithelial-mesenchymal transition in a pro-metastatic niche of renal cell carcinoma.
Molecular function validation and prognostic value analysis of the cuproptosis-related gene ferredoxin 1 in papillary thyroid carcinoma.
Gut microbiota-bile acid crosstalk contributes to calcium oxalate nephropathy through Hsp90α-mediated ferroptosis.
P4HA2 promotes the progression of papillary thyroid cancer by enhancing degradation of IκBα to activate NF-κB signaling pathway.
XBP1 promotes endometrial fibrosis through cGAS-STING signaling pathway in intrauterine adhesion.
Cathepsin S mediates the disruption of airway epithelial Pannexin 1 via an Akt-dependent pathway in an LPS-induced murine model of acute lung injury.
Secreted phosphoprotein 1 promotes the activation of keloid fibroblasts via the CD44/TGF-β1/Smad pathway.
Elevated SGO2 expression in lung adenocarcinoma promotes migration and invasion via MAD2 and correlates with poor prognosis.
Integrative proteomics and metabolomics analyses reveals the regulation of autophagy and ferroptosis by RAB10 through Slc37a2/mTOR pathway in breast cancer.
Keratin 6A Overexpression in the Lymphovascular Invasion-Associated Tumor Subgroup Promotes Progression of Triple-Negative Breast Cancer.
Enhancing the therapeutic efficacy of gemcitabine in bladder cancer through TGF-β1 inhibition and pluronic F-127-based microsphere delivery.
TMEM150A overexpression was associated with poor prognosis and cancer progression in glioma verified by comprehensive analysis and cell experiments.
MTMR14 depletion aggravates intrapulmonary inflammation and emphysema in experimental COPD through activating macrophage M1 polarization.
Biological and metabolomic insights into RACGAP1-mediated growth and progression of clear cell renal cell carcinoma.
DNMT3B aggravated renal fibrosis in diabetic kidney disease via activating Wnt/β-catenin signaling pathway.
FOXL2 Knockdown Inhibits the Progression of Endometriosis.
Complement factor H drives idiopathic pulmonary fibrosis by autocrine C3 regulation, suppressing macrophage phagocytosis and enhancing fibrotic progression.
Network pharmacology, molecular docking, and experimental verification to reveal the mechanism of colquhounia root tablet in the treatment of diabetic nephropathy.
Wnt5a promotes VM formation by modulating the stemness and EMT progression of prostate cancer cell.
Slit2 Promotes H(2)O(2)-Induced Lens Epithelial Cells Oxidative Damage and Age-Related Cataract.
Centromere protein K enhances the activation of YAP1/TAZ signal cascade to drive the progression of clear cell renal cell carcinoma.
EML4-ALK G1202R and EML4-ALK L1196M mutations induce crizotinib resistance in non-small cell lung cancer cells through activating epithelial-mesenchymal transition mediated by MDM2/MEK/ERK signal axis.
ATF1 regulates MAL2 expression through inhibition of miR-630 to mediate the EMT process that promotes cervical cancer cell development and metastasis.
Dental pulp stem cell‑derived extracellular vesicles loaded with hydrogels promote osteogenesis in rats with alveolar bone defects.
NKD2 as a Mediator of IFIX Antioncogene-Induced Wnt Signalling and Epithelial-Mesenchymal Transition in Human OSCC.
Trametinib and M17, a novel small molecule inhibitor of AKT, display a synergistic antitumor effect in triple negative breast cancer cells through the AKT/mTOR and MEK/ERK pathways.
Wenshen Yiqi Granule Alleviates Chronic Obstructive Pulmonary Disease via the Long Noncoding RNA-XIST/MicroRNA-200c-3p Axis.
NAP1L5 promotes epithelial-mesenchymal transition by regulating PEG10 expression in acute myeloid leukaemia.
Modified Zuojin pill alleviates gastric precancerous lesions by inhibiting glycolysis through the HIF-1α pathway.
TIFA enhances glycolysis through E2F1 and promotes the progression of glioma.
Morusin Reverses Epithelial-Mesenchymal Transition in Gallbladder Cancer Cells by Regulating STAT3/HIF-1α Signaling.
Estrogen Receptor β Activation Mitigates Colitis-associated Intestinal Fibrosis via Inhibition of TGF-β/Smad and TLR4/MyD88/NF-κB Signaling Pathways.
Cromolyn sodium reduces LPS-induced pulmonary fibrosis by inhibiting the EMT process enhanced by MC-derived IL-13.
MYBL2 promotes proliferation of clear cell renal cell carcinoma by regulating TOP2A and activating AKT/mTOR signaling pathway.
Pharmacological effects and mechanisms of danlong oral liquid in asthma airway remodeling: Insights from serum medicinal chemistry, network pharmacology, and experimental validation.
Emodin reverses sorafenib resistance in hepatocellular carcinoma by inhibiting epithelial-mesenchymal transition via the Akt signaling pathway.
Xihuang pill suppresses breast cancer malignancy by inhibiting TGF-β signaling and acquires chemotherapy benefits.
Formin protein DAAM1 positively regulates PD-L1 expression via mediating the JAK1/STAT1 axis in pancreatic cancer.
DRAM1 enhances the proliferation and metastasis of gastric cancer through the PI3K/AKT/mTOR signaling pathway and energy metabolism.
Synergistic inhibition of colorectal cancer progression by silencing Aurora A and the targeting protein for Xklp2.
UHRF1 promotes epithelial-mesenchymal transition mediating renal fibrosis by activating the TGF-β/SMAD signaling pathway.
Co-exposure to polyethylene microplastics and house dust mites aggravates airway epithelial barrier dysfunction and airway inflammation via CXCL1 signaling pathway in a mouse model.
A novel USP4 inhibitor that suppresses colorectal cancer stemness by promoting β-catenin and Twist1 degradation.
Discovery of Novel Small-Molecule Inhibitors Disrupting the MTDH-SND1 Protein-Protein Interaction.
Wearable electrodriven switch actively delivers macromolecular drugs to fundus in non-invasive and controllable manners.
A tunable human intestinal organoid system achieves controlled balance between self-renewal and differentiation.
Time-series single-cell transcriptomic profiling of luteal-phase endometrium uncovers dynamic characteristics and its dysregulation in recurrent implantation failures.
Hypoxia-induced circPLOD2a/b promotes the aggressiveness of glioblastoma by suppressing XIRP1 through binding to HuR.
Blue light promotes conjunctival epithelial-mesenchymal transition and collagen deposition through ITGB4.
MicroRNA-150-3p enhances the antitumour effects of CGP57380 and is associated with a favourable prognosis in non-small cell lung cancer.
Photo-Crosslinking Hydrogel Based on Porcine Small Intestinal Submucosa Decellularized Matrix/Fish Collagen/GelMA for Culturing Small Intestinal Organoids and Repairing Intestinal Defects.
EIF4A3-Mediated circ_0008126 Inhibits the Progression and Metastasis of Gastric Cancer by Modulating the APC/β-Catenin Pathway.
Myristoylated Eepd1 Enhances Lipolysis and Thermogenesis through PKA Activation to Combat Obesity.
Molecule interacting with CasL-2 enhances tumor progression and alters radiosensitivity in cervical cancer.
Bisphenol S exposure promotes stemness of triple-negative breast cancer cells via regulating Gli1-mediated Sonic hedgehog pathway.
SPHK1/S1PR1/PPAR-α axis restores TJs between uroepithelium providing new ideas for IC/BPS treatment.
circ_0004662 contributes to colorectal cancer progression by interacting with hnRNPM.
NEK2 Promotes ESCC Malignant Progression by Inhibiting Cellular Senescence via the FOXM1/c-Myc/p27 Signaling Pathway.
Novel Diagnostic Biomarker BST2 Identified by Integrated Transcriptomics Promotes the Development of Endometriosis via the TNF-α/NF-κB Signaling Pathway.
β-Catenin mediated TAM phenotype promotes pancreatic cancer metastasis via the OSM/STAT3/LOXL2 axis.
Epigenetic silencing of JAM3 promotes laryngeal squamous cell carcinoma development by inhibiting the Hippo pathway.
Hypericin mediated photodynamic therapy induces ferroptosis via inhibiting the AKT/mTORC1/GPX4 axis in cholangiocarcinoma.
RNF144A-AS1 stabilizes TAF15 and promotes malignant biological behaviors of skin cutaneous melanoma.
Ilicicolin C suppresses the progression of prostate cancer by inhibiting PI3K/AKT/mTOR pathway.
TWIST1 Regulates FOXM1/β-Catenin to Promote the Growth, Migration, and Invasion of Ovarian Cancer Cells by Activating MFAP2.
SETD7 promotes LC3B methylation and degradation in ovarian cancer.
FBXO2 as a switch guides a special fate of tumor clones evolving into a highly malignant transcriptional subtype in oral squamous cell carcinoma.
PRELP inhibits colorectal cancer progression by suppressing epithelial-mesenchymal transition and angiogenesis via the inactivation of the FGF1/PI3K/AKT pathway.
Organophosphate flame retardant triphenyl phosphate (TPhP) induced colonic fibrosis by bringing about epithelial-mesenchymal transition.
Prenatal Perfluorooctanoic Acid (PFOA) exposure causes reproductive toxicity by disrupting the formation of transzonal projections (TZPs) and down-regulating Wnt4/β-catenin signaling pathway in progeny.
The Oncopromoting Gene RBM6 Inhibits Prostate Tumour Cell Migration During Epithelial-to-Mesenchymal Transition.
Dedicator of cytokinesis protein 2 activates the epithelial-mesenchymal transition in renal fibrosis through the Rac1/PI3K/AKT pathway.
LAMP3-mediated epithelial-mesenchymal transition promotes the invasion and excessive proliferation of fibroblast-like synoviocytes in rheumatoid arthritis.
Yiqi Huayu Jiedu formula inhibits JAK2/STAT3-mediated partial EMT in treating chronic atrophic gastritis.
HECW1-Mediated Ubiquitination of HIPK2 Drives Metastasis in Gastric Cancer Through the AKT Signaling Pathway.
Endoplasmic reticulum stress-related CLIP4 plays a procarcinogenic role in hepatocellular carcinoma: an integrated analysis.
Non-lethal sonodynamic therapy mitigates hypertensive renal fibrosis through the PI3K/AKT/mTORC1-autophagy pathway.
PTOV1 exerts pro-oncogenic role in colorectal cancer by modulating SQSTM1-mediated autophagic degradation of p53.
MSC-exosomes pretreated by Danshensu extracts pretreating to target the hsa-miR-27a-5p and STAT3-SHANK2 to enhanced antifibrotic therapy.
Discovery of Novel Aromatic Urea-Imidazole Salt Derivatives for Cancer Therapy via Targeting ERK1/2.
SJB2-043, a USP1 Inhibitor, Suppresses A549 Cell Proliferation, Migration, and EMT via Modulation of PI3K/AKT/mTOR, MAPK, and Wnt Signaling Pathways.
Molecular mechanism of Gancao Xiexin Decoction regulating EMT and suppressing hepatic metastasis of gastric cancer via the TGF-β1/SMAD pathway.
PTPRO represses breast cancer lung metastasis by inhibiting the JAK2-YAP axis.
The inhibition of ZC3H13 attenuates G2/M arrest and apoptosis by alleviating NABP1 m6A modification in cisplatin-induced acute kidney injury.
Phosphorylation of FOXN3 by NEK6 promotes pulmonary fibrosis through Smad signaling.
Autocrine small extracellular vesicles induce tubular phenotypic transformation in diabetic nephropathy via miR-21-5p.
Hypoxia-Induced VGF Promotes Cell Migration and Invasion in Prostate Cancer via the PI3K/Akt Axis.
Interferon regulatory factor 5 attenuates kidney fibrosis through transcriptional suppression of Tgfbr1.
A novel piperine derivative HJJ_3_5 inhibits colorectal cancer progression by modulating EMT signaling pathways.
Constructing a highly sensitive duplex immunoassay using AuNPs and AgNPs as nanolabels for investigating the epithelial-mesenchymal transition occurring on circulating tumor cells with lung cancer patients.
Multi-omics analysis reveals the impact of YAP/TEAD4-mediated EIF5A1 expression on mitochondrial apoptosis and bladder cancer progression.
Ultrasound nanobubble-based combinational strategies of loaded miR-107-3p and CD133 Ab for anti-PD-L1 and anti-hepatocellular cancer stem cells.
Magnolol preserves the integrity of the intestinal epithelial barrier and mitigates intestinal injury through activation of PPAR γ in COPD rat.
CircRNA circACTN4 Promotes the Progression of Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma by Targeting the miR-424-5p/NCAPG/Wnt Axis.
B7-H3 enhances the malignant phenotype of colorectal cancer by activating the Wnt/β-catenin pathway mediated by CYP1B1.
IMUP promotes fatty acid metabolism and lung cancer progression by regulating TGF-β/SMAD3 signaling pathway.
FOXA1 Transcriptional Repression of PLSCR1 Inhibits Tongue Squamous Cell Carcinoma Progression.
TTK Defines a High-Risk Oral Squamous Cell Carcinoma Subtype Through Dual mTORC1/NF-κB Activation.
miR‑100‑5p and miR‑203a‑3p suppress esophageal squamous cell carcinoma progression by targeting FKBP5.
LARS1 Promotes Tubular Epithelial Cells Epithelial Mesenchymal Transition in Chronic Kidney Disease by Inhibiting Lipophagy.
Unraveling the miR-144-3p/PUMA pathway: a novel regulator of FDX1-mediated cuproptosis in colorectal cancer.
Taohong Siwu Decoction relieves renal fibrosis: based on network pharmacology and experimental confirmation.
Identification of biomarkers for chronic renal fibrosis and their relationship with immune infiltration and cell death.
TM4SF1 as a Prognostic Biomarker and Therapeutic Target in Cervical Cancer.
Mechanistic insights into FUNDC2P4 and HSF1 regulation of EMT in residual hepatocellular carcinoma following insufficient radiofrequency ablation.
TLyp-1-modified exosome-mediated delivery of circRAPGEF5 ASO inhibits lung adenocarcinoma metastasis via regulating the miR-570-3p/SPP1 axis.
CircRAB23 functions as miR-532-3p sponge to promote the malignant proliferation and metastasis of intrahepatic cholangiocarcinoma through HMGA2-EMT axis.
Cholesterol metabolism in LUAD progression: GJB3 as a key target for cell‑based therapeutic interventions.
The Effect of Prenatal Dexamethasone Exposure on Placental Morphology and Function at Different Stages, Doses, and Courses In Mice.
GLDC interacts with VPS34 to inhibit tumorigenesis and epithelial-mesenchymal transition in hepatocellular carcinoma.
CircATP5C1 promotes triple-negative breast cancer progression by binding IGF2BP2 to modulate CSF-1 secretion.
Upregulation of TTYH3 by lncRNA LUCAT1 through interacting with ALYREF facilitates the metastasis in non-small cell lung cancer.
Macrophage extracellular traps impair intestinal barrier function in DSS-induced colitis in mice by inducing intestinal epithelial cell apoptosis.
ACOD1/Itaconate regulates trophoblast function through the PI3K/Akt/FOLR1 axis to participate in the pathogenesis of recurrent spontaneous abortion.
The role and mechanisms of the microRNA-1180-3p/MKNK2/CREB3 signaling axis in tumor progression following insufficient radiofrequency ablation of colorectal cancer liver metastasis.
Juglone targets MMP-1 to inhibit gastric cancer progression.
Single-Cell and Spatial Transcriptomics-Based Research Reveals Association Between M2a Macrophages and Tumor Spread through Air Spaces in Lung Adenocarcinoma.
Acyl-CoA dehydrogenase long chain acts as a tumor-suppressive factor in lung adenocarcinoma progression.
Targeting the ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (ST3Gal1) as a potential therapeutic strategy to overcome anti-VEGF resistance in endometrial cancer.
Desulfovibrio vulgaris flagellin exacerbates colorectal cancer through activating LRRC19/TRAF6/TAK1 pathway.
Novel role of FTO in regulation of gut-brain communication via Desulfovibrio fairfieldensis-produced hydrogen sulfide under arsenic exposure.
Neutrophil extracellular trap-borne C3-driven endothelial dysfunction in Klebsiella pneumoniae liver abscess.
Hypoxia-induced secretory autophagy in cancer-associated fibroblasts promotes ECM remodelling through serglycin secretion in oral squamous cell carcinoma.
Targeting renal tubular epithelial cells via a dual functionalized oligosaccharide self-assembly in the management of acute and chronic kidney diseases.
Adipose-derived mesenchymal stem cell exosomes protect keratinocytes from high-glucose injury by modulating KEAP1/NRF2/HO-1 axis.
GPR108 deficiency promotes urate-induced renal interstitial fibrosis.
Formononetin, a Key Component of Danggui Buxue Decoction, Inhibits Metastasis of Triple-Negative Breast Cancer by Modulating SNAI2-Driven EMT.
CircLRBA Promotes Epithelial-Mesenchymal Transition, Immune Evasion, Chemoimmunotherapy Resistance and Metastasis Through Stabilizing Twist1.
Synergistic Promotion of Triple-Negative Breast Cancer Tumorigenesis and Metastasis by Oral Polystyrene Nanoplastics Exposure via Alloprevotella-Derived Glutamate and Platelet Activation.
Skullcapflavone II Inhibits SLC1A4-Mediated L-Serine Uptake and Promotes Mitochondrial Damage in Gastric Cancer.
In Vitro Evidence for Oral Soft Tissue Regenerative Effects of a Polynucleotide-Hyaluronan Formulation.
METTL3-mediated m(6)A modification regulates OSCC progression via the HNRNPA2B1/FOXQ1 axis.
Periodic asymmetric field enhances electrofusion of nanoscale lipid systems.
The SREBF2-ACOT7 axis promotes tumor progression and predicts prognosis in diffuse large b-cell lymphoma.
Exosome-derived Menin from cancer-associated fibroblasts promotes gastric cancer progression by activating the HSPA6/JNK/JunD pathway and inducing EMT.
PLS3 Is a Prognostic Biomarker and Correlates with Immune Infiltrates in Head and Neck Squamous Cell Carcinoma.
KY216-tubulin complex captures VASH2 to inhibit NSCLC metastasis.
Bile metabolite palmitic acid augments the migration of gallbladder cancer cells through the ROS/NF-кB signaling pathway.
HMGB1-enhanced autophagic degradation of E-cadherin facilitates mesothelial trans-differentiation and postoperative peritoneal adhesion.
TAGLN: a stiffness-driven prognostic biomarker for metastatic colorectal cancer.
Six1 promotes alveolar epithelium senescence in pulmonary fibrosis through regulating Tp53.
EXOSC3 knockdown induces G1/S phase arrest to suppress hepatocellular carcinoma cell proliferation.
Integrating Network Pharmacology, Machine Learning, and Experimental Validation to Elucidate the Mechanism of Cardamonin in Treating Idiopathic Pulmonary Fibrosis.
Shikonin inhibits multiple tumor malignant phenotypes and is associated with Hedgehog pathway downregulation in lung adenocarcinoma.
FOXL2 + cancer-associated fibroblasts enhances epithelial ovarian cancer development via TGFβ/Smad signaling.
PAK2 promotes CTC cluster formation by phosphorylating E-cadherin to enhance cell-cell adhesion in breast cancer.
[PSMD11 overexpression promotes epithelial-mesenchymal transition in gastric cancer and affects patient prognosis].
GPX8 is transcriptionally regulated by KLF16 and promotes osteosarcoma progression.
A novel super-enhancer-driven lncRNA LINC00973 governs head and neck squamous cell carcinoma progression through EN2.
Targeting the SMAD3/CISD2 axis suppresses bladder cancer progression by promoting ferroptosis in mesenchymal-like bladder cancer cells.
METTL3-mediated m6A modification of TACSTD2 mRNA inhibits papillary thyroid cancer progression by activating the TNF signaling and blocking epithelial-mesenchymal transition.
The role of hsa_circ_0000520 in breast cancer progression: insights into the miR-542-3p/TMBIM6 regulatory axis.
S1PR3 Inhibition in alveolar epithelial cells alleviates pulmonary fibrosis by enhancing alveolar barrier function.
Lung adenocarcinoma cells respond differently to mechanical stress in 3D versus 2D environments.
Remimazolam attenuates traumatic brain injury-induced acute lung injury by suppressing pulmonary epithelial pyroptosis.
Haematococcus pluvialis ameliorates renal fibrosis by restoring mitophagy via PINK1-Parkin-p62-LC3 signaling.
CD36-mediated fatty acid metabolic reprogramming activates synovial fibroblasts and promotes rheumatoid arthritis progression.
CircRNA hsa_ circ_0009022 inhibits colorectal cancer progression by sponging miR-576-5p and complexing with FMRP.
ZEB1 Contributes to Drug Resistance Through Canonical Wnt Signaling in Lung Cancer.
The role of formin-like protein 1 in pancreatic cancer and its specific effects on immunity.
METTL1-mediated m7G modification promotes colorectal cancer metastasis via stabilization of ICAM-1.
P5CS deacetylation mediated by SIRT2 facilitates tumor growth by enhancing mitochondrial respiration in hepatocellular carcinoma.
Application of PVA hydrogel loaded with luteolin nanoparticles in anti EMT treatment after GBM.
Thermosensitive hydrogel composite with si-Cx43 nanoparticles and anti-VEGF agent for synergistic treatment of diabetic retinopathy.
circGAPVD1 inhibits the progression of gastric cancer through miR-4424/STK4 axis and encoding GAPVD1-137aa protein.
Lactoferrin prevents heat stroke-induced intestinal barrier damage by reducing ferroptosis via regulating MAPK signaling pathway: In vitro and in vivo studies.
Dysregulated RNA m6A Methylation Contributes to the Metastasis of Gallbladder Cancer Through miR-146a-5p.
p66shc exacerbates the progression of obstructive nephropathy through apoptosis, mitochondrial damage, and EMT.
m6A-mediated regulation of ECA39 promotes renal fibrosis in chronic kidney disease by enhancing glycolysis and epithelial-mesenchymal transition.
Gestational TCBPA exposure impairs placental function and fetal Development: Mechanisms of syncytialization disruption and fetal growth restriction.
Revealing a new target: Celastrol alleviates pulmonary fibrosis by inhibiting PCAF.
Pyrrolidinium Fullerenes as YTHDF1 Inhibitors for Targeted Tumor Therapy.
F-box only protein 10 protects against kidney tubulointerstitial fibrosis by inhibiting ACSL4-mediated lipid peroxidation and ferroptosis.
HnRNPR promotes non-small cell lung cancer progression by protecting XB130 mRNA from XRN1- and DIS3L2-mediated degradation.
Circ847 upregulation via CAFs suppresses salivary adenoid cystic carcinoma progression through VIM-EMT.
GATA2 promotes cervical cancer progression under the transcriptional activation of TRIP4.
Gut microbiota promote the propagation of pathologic α-syn from gut to brain in a gut-originated mouse model of Parkinson's disease.
Nanoparticle conjugation of ginsenoside Rh2 enhanced antitumor efficacy on hepatocellular carcinoma.
ZC3H13 mediates N6-methyladenosine modification of SNTB1 to promote epithelial-mesenchymal transition in gastric cancer.
Neurotensin receptor1 signaling promotes progression of epithelial-mesenchymal transition in mice with chronic rhinosinusitis through Wnt3a/β-catenin pathway.
Emodin-Enhanced hUC-MSC extracellular vesicles alleviate acute pancreatitis by targeting inflammation and pyroptosis.
G-protein coupled receptor 183 (GPR183) inhibits visceral metastasis of non-small cell lung cancer.
Promotion of the invasion and metastasis of breast cancer by B7-H3 through CCR5High tumor-associated macrophages.
Role of the transcription factor SOX8 in hepatocellular carcinoma development and lymph node metastasis.
Beyond energy metabolism: ketogenic diet and β-hydroxybutyrate protect against intestinal ischemia-reperfusion injury through anti-inflammatory and barrier-preserving effects.
DDX18 promotes growth and metastasis of hepatocellular carcinoma via activating EMT and MAPK signaling.
Exosomal Biglycan promotes gastric cancer progression via M2 polarization and CXCL10-mediated JAK/STAT1 activation.
Inhibition of macrophage extracellular traps by Metrnl/IL-41 suppresses airway remodeling in asthma.
Protein lactylation of citrate synthase promotes the AKI-CKD transition by activating the NLRP3 inflammasome.
Paris saponin VII restrains PD-L1 mediated immune evasion through the AKT1 and STAT3 signaling pathways.
Association of lipoprotein(a) and LPA gene with calcific aortic valve disease.
CircZFR/YTHDF3 axis drives lymph node metastasis in cervical cancer via FASN translation.
Osteopontin derived from hypoxia-induced M2 macrophages promotes osteosarcoma progression through modulation of EGR3/ISG15 signaling and RIG-I expression.
Supersulfides regulate cell migration in human skin keratinocytes.
METTL3 promotes peritoneal metastasis of colorectal cancer through regulating m6A modification of NRXN3 mRNA.
Suppressive effects of Momordica charantia MAP30 on the senescence, proliferation and migration of bladder cancer cells mediated by CENPA.
miRNA-204-5p acts as a tumor suppressor in gastric cancer by inhibiting cell migration, invasion, and glycolysis via the RAB22A/PI3K/AKT axis.
Glia maturation factor-β in hepatocytes enhances liver regeneration and mitigates steatosis and ballooning in zebrafish.
Akkermansia muciniphila Protects Against Trinitrobenzene Sulfonic Acid Induced Colitis by Inhibiting IL6/STAT3 Pathway.
TGF-β1 induces ROS to activate ferroptosis via the ERK1/2-WISP1 pathway to promote the progression of renal tubular epithelial cell fibrosis.
The Long Noncoding RNA Gall Bladder Cancer-Associated Suppressor of Pyruvate Carboxylase Inhibits the Proliferation, Migration, and Invasion of Colorectal Cancer Cells and Induces Their Apoptosis.
Tumor-stroma proportion is associated with increased M2 macrophage abundance and predicts the resistance to immune checkpoint blockade in breast cancer.
Hypoxic Cancer Cells-Derived Exosomes Strengthen the Development of Cancer Stem Cell-Like Properties Through Delivering LINC00665 in Thyroid Cancer Cells.
PLEK2 promotes migration and invasion in pancreatic ductal adenocarcinoma by MMP1 through IL-17 pathway.
Low molecular weight heparins promote migration and invasion of trophoblast cells through regulating the PI3K/AKT signaling pathway.
Cinobufacini Inhibits Survival and Metastasis of Hepatocellular Carcinoma via c-Met Signaling Pathway.
Constructing a 3D co-culture in vitro synovial tissue model for rheumatoid arthritis research.
HDAC3 and Snail2 complex promotes melanoma metastasis by epigenetic repression of IGFBP3.
Pinocembrin alleviates renal ischemia-reperfusion injury/unilateral ureteral obstruction (UUO)-generated renal fibrosis by targeting the CYP1B1/ROS/MAPK axis.
FOXA2 Loss in TGF-β1-Induced EMT Suppresses Bisecting-GlcNAc N-Glycan Synthesis in Lung Adenocarcinoma.
Design, Synthesis, and Biological Evaluation of Naphthalimide-Polyamine Conjugate as a Potential Anti-Colorectal Cancer Agent.
Design, synthesis and antitumor activity evaluation of novel modified 18β-glycyrrhetinate derivatives as PPARγ agonists.
Bioinformatics Combined With Biological Experiments to Identify the Pathogenetic Link of Type 2 Diabetes for Breast Cancer.
Isoforskolin, adenylate cyclase agonist, inhibits endothelial-to-mesenchymal transition in atherosclerosis.
Cannabidiol Enhances the Anticancer Activity of Etoposide on Prostate Cancer Cells.
Escin Ia ameliorates DSS-induced chronic colitis in mice by inhibiting inflammation and oxidative stress via the LOXL2/MMP-9 pathway.
ELK4 induced upregulation of HOMER3 promotes the proliferation and metastasis in glioma via Wnt/β-catenin/EMT signaling pathway.
Development and Validation of a Prognostic Model for Lung Adenocarcinoma Based on CAF-Related Genes: Unveiling the Role of COX6A1 in Cancer Progression and CAF Infiltration.
Micro-proteomics reveals distinct protein profiles and SPARC/FGF2/CDH1 regulation of human Sertoli cells between Sertoli cell-only syndrome and normal men.
Investigation of c-Fos/c-Jun Signaling Pathways in Periostracum Cicadae's Inhibition of EMT in Gastric Tissue.
Targeting alveolar epithelial cells with lipid micelle-encapsulated necroptosis inhibitors to alleviate acute lung injury.
Cancer-associated fibroblasts secrete CSF3 to promote TNBC progression via enhancing PGM2L1-dependent glycolysis reprogramming.
A comprehensive analysis of deubiquitinase USP20 on prognosis and immunity in pan-cancer.
Natural Killer Cell Activation Signature Identifies Cyclin B1/CDK1 as a Druggable Target to Overcome Natural Killer Cell Dysfunction and Tumor Invasiveness in Melanoma.
The highly expressed GOLPH3 in colorectal cancer cells activates smoothened to drive glycolysis and promote cancer cell growth and radiotherapy resistance.
Dasatinib demonstrates efficacy in organoid derived paclitaxel-resistant Trp53/Cdh1-deficient mouse gastric adenocarcinoma with peritoneal metastasis.
KIF2C promotes oral squamous cell carcinoma progression via PLK1 upregulation: implications for biomarker development and therapeutic targeting.
HNF4α-Mediated LINC02560 Promotes Papillary Thyroid Carcinoma Progression by Targeting the miR-505-5p/PDE4C Axis.
PYK2 promotes cell proliferation and epithelial-mesenchymal transition in endometriosis by phosphorylating Snail1.
Cornua cervi degelatinatum inhibits breast cancer stem-like cell properties and metastasis via miR-148a-3p-mediated TGF-β/Smad2 pathway.
Development of Novel PRMT7 Inhibitors for the Treatment of Prostate Cancer.
Mechanism of Astragalus Polysaccharide in Alleviating Bovine Mammary Fibrosis Through ROS/NLRP3 Inhibition and EMT Regulation.
THBS2-producing matrix CAFs promote colorectal cancer progression and link to poor prognosis via the CD47-MAPK axis.
CD147 regulates the Rap1 signaling pathway to promote proliferation, migration, and invasion, and inhibit apoptosis in colorectal cancer cells.
HPV11E6/E7 induces nasal epithelial hyperplasia through JAK2/STAT3 signaling pathway.
DCC-2036 inhibits osteosarcoma via targeting HCK and the PI3K/AKT-mTORC1 axis to promote autophagy.
P4HA1 is highly expressed in gastric cancer and promotes proliferation and metastasis of gastric cancer cells.
PRC1 as an independent adverse prognostic factor in Wilms tumor via integrated bioinformatics and experimental validation.
PPM1G dephosphorylates α-catenin to maintain the integrity of adherens junctions and regulates apoptosis in Sertoli cells.
STEAP4 facilitates growth, migration, and invasion of prostate carcinoma through upregulation of NOTCH4.
VRK1 promotes epithelial-mesenchymal transition in hepatocellular carcinoma mediated by SNAI1 via phosphorylating CHD1L.
The LysoPS/GPR174 axis drives metastatic progression in esophageal squamous cell carcinoma through cAMP-PKA-CREB signaling activation.
CDC25A inhibition sensitizes melanoma cells to doxorubicin and NK cell therapy.
Oroxylin A may promote cell apoptosis and inhibit epithelial-mesenchymal transition in endometrial cancer, associated with the ERβ/PI3K/AKT pathway.
YTHDF3 drives tumor growth and metastasis by recruiting eIF4B to promote Notch2 translation in breast cancer.
Bisphenol A-induced cancer-associated adipocytes promotes breast carcinogenesis via CXCL12/AKT signaling.
Lack of ALCAT1 enhances the protective effects of aerobic exercise on kidney in HFpEF mice.
A Hybrid Manganese Nanoparticle Simultaneously Eliminates Cancer Stem Cells and Activates STING Pathway to Potentiate Cancer Immunotherapy.
Endoglin promotes cell migration and invasion in endometriosis by regulating EMT.
Single-Cell Spatial-Temporal Analysis of ZNF451 in Mediating Drug Resistance and CD8(+) T Cell Dysfunction.
Long non-coding RNA HOTAIR promotes tumourigenesis by affecting proliferation, invasion, migration, and apoptosis of liver cancer cells.
Inhibition of IGF2BP1 attenuates the progression of endometriosis through PTBP1.
Inhibition of anlotinib-induced autophagy attenuates invasion and migration by regulating epithelial-mesenchymal transition and cytoskeletal rearrangement through ATG5 in human osteosarcoma cells.
Characterization and optimization of variability in a human colonic epithelium culture model.
Cell Membrane-Coated Nanotherapeutics for the Targeted Treatment of Acute and Chronic Colitis.
Vaporization of perfluorocarbon attenuates sea-water-drowning-induced acute lung injury by deactivating the NLRP3 inflammasomes in canines.
α-Mangostin reduces hypertension in spontaneously hypertensive rats and inhibits EMT and fibrosis in Ang II-induced HK-2 cells.
Matrix Metalloproteinase 11 Promotes Migration and Invasion of Colorectal Cancer by Elevating Slug Protein.
Knockdown of ribosomal protein L22-like 1 arrests the cell cycle and promotes apoptosis in colorectal cancer.
Cryptotanshinone Inhibits Bladder Cancer Cell Malignant Progression in a Lipopolysaccharide-Induced Inflammatory Microenvironment through NLRP3 Inhibition.
TSPAN6 reinforces the malignant progression of glioblastoma via interacting with CDK5RAP3 and regulating STAT3 signaling pathway.
RUNX1-PDIA5 Axis Promotes Malignant Progression of Glioblastoma by Regulating CCAR1 Protein Expression.
METTL16 Promotes Stability of SYNPO2L mRNA and leading to Cancer Cell Lung Metastasis by Secretion of COL10A1 and attract the Cancer-Associated Fibroblasts.
Hypoxia-driven TNS4 fosters HNSCC tumorigenesis by stabilizing integrin α5β1 complex and triggering FAK-mediated Akt and TGFβ signaling pathways.
Irisin ameliorates UUO-induced renal interstitial fibrosis through TGF-β1/periostin/MMP-2 signaling pathway.
Interference with mitochondrial metabolism could serve as a potential therapeutic strategy for advanced prostate cancer.
The H2Valdien derivatives regulate the epithelial-mesenchymal transition of hepatoma carcinoma cells through the Hedgehog signaling pathway.
PTTG1 induces pancreatic cancer cell proliferation and promotes aerobic glycolysis by regulating c-myc.
Combined miR-181a-5p and Ag Nanoparticles are Effective Against Oral Cancer in a Mouse Model.
Nebulization of Hypoxic hUCMSC-EVs Attenuates Airway Epithelial Barrier Defects in Chronic Asthma Mice by Transferring CAV-1.
miR-34b-5p suppresses the epithelial-mesenchymal transition and metastasis in endometrial cancer AN3CA cells by targeting ZEB1.
Pan-Cancer Screening and Validation of CALU's Role in EMT Regulation and Tumor Microenvironment in Triple-Negative Breast Cancer.
Progerin Inhibits the Proliferation and Migration of Melanoma Cells by Regulating the Expression of Paxillin.
WTAP knockdown inhibits cell migration through regulating SNAIL1 expression in colorectal cancer.
Heparan sulfate 6-O-sulfotransferase 2 promotes gastric cancer progression by modulating the TGF-β/smad2/3 pathway.
Human umbilical cord mesenchymal stem cells derived-exosomes alleviate LPS-induced cervical inflammation and epithelial-mesenchymal transition.
NEDD1 overexpression increases cell proliferation, tumor immune escape, and drug resistance in LUAD.
KRT80 Promotes Lung Adenocarcinoma Progression and Serves as a Substrate for VCP.
Pan-Cancer Analysis of PGAM1 and Its Experimental Validation in Uveal Melanoma Progression.
Integrative Omics Analysis Reveals Metabolic Features of Ground-Glass Opacity-Associated Lung Cancer.
LncRNA PRKCA-AS1 promotes LUAD progression and function as a ceRNA to regulate S100A16 by sponging miR-508-5p.
IPCEF1: Expression Patterns, Clinical Correlates and New Target of Papillary Thyroid Carcinoma.
DOK1 facilitates the advancement of ccRCC.
The transcription factor ZNF248 promotes colorectal cancer metastasis by binding to ZEB1.
DPP7 as a Potential Therapeutic Marker for Colorectal Cancer.
MPP7 mediates EMT via Wnt/β-catenin pathway to promote polarity changes in epithelial ovarian cancer cells.
Hypoxia-responsive gene F3 Promotes GBM Cell Proliferation and Migration through Activating NF-κB/p65 Signaling Pathway.
Elevated RACGAP1 Expression Enhances Malignant Potential in Lung Adenocarcinoma and Serves as a Prognostic Factor.
CSF2 Impairs Nrf2 Signaling through the Akt/Mtor Pathway in the Development of Bladder Cancer.
PSAT1 mediated EMT of colorectal cancer cells by regulating Pl3K/AKT signaling pathway.
NUP155 and NDC1 interaction in NSCLC: a promising target for tumor progression.
Danshen injection ameliorates unilateral ureteral obstruction-induced renal fibrosis by inhibiting ferroptosis via activating SIRT1/GPX4 pathway.
ABCA1 promote tumor environment heterogeneity via epithelial mesenchymal transition in Huh7 and HepG2 liver cancer cell.
Macranthoidin B restrains the epithelial-mesenchymal transition through COX-2/PGE(2) pathway in endometriosis.
The mechanism of PDE7B inhibiting the development of hepatocellular carcinoma through oxidative stress.
PFKFB3 deprivation attenuates the cisplatin resistance via blocking its autophagic elimination in colorectal cancer cells.
Thonningianin A ameliorated renal interstitial fibrosis in diabetic nephropathy mice by modulating gut microbiota dysbiosis and repressing inflammation.
Heat acclimation with probiotics-based ORS supplementation alleviates heat stroke-induced multiple organ dysfunction via improving intestinal thermotolerance and modulating gut microbiota in rats.
Identifying and assessing a prognostic model based on disulfidptosis-related genes: implications for immune microenvironment and tumor biology in lung adenocarcinoma.
Integrated analysis reveals crosstalk between pyroptosis and immune regulation in renal fibrosis.
The long non-coding RNA CCAT1 promotes erlotinib resistance in cholangiocarcinoma by inducing epithelial-mesenchymal transition via the miR-181a-5p/ROCK2 axis.
Extracellular putrescine can augment the epithelial-mesenchymal transition of gastric cancer cells by promoting MAL2 expression by elevating H3K27ac in its promoter region.
Resveratrol restrains colorectal cancer metastasis by regulating miR-125b-5p/TRAF6 signaling axis.
FSH induces EMT in ovarian cancer via ALKBH5-regulated Snail m6A demethylation.
POLR2J expression promotes glioblastoma malignancy by regulating oxidative stress and the STAT3 signaling pathway.
SSH3 promotes pancreatic cancer proliferation and migration by activating the notch signaling pathway.
High glucose-induced NCAPD2 upregulation promotes malignant phenotypes and regulates EMT via the Wnt/β-catenin signaling pathway in HCC.
FLNB overexpression promotes tumor progression and associates with immune suppression, evasion and stemness in pancreatic cancer.
MAFG-DT promotes prostate cancer bone metastasis through activation of the Wnt/β-catenin pathway.
Identification of hub genes within the CCL18 signaling pathway in hepatocellular carcinoma through bioinformatics analysis.
Early short-term hypoxia promotes epidermal cell migration by activating the CCL2-ERK1/2 pathway and epithelial-mesenchymal transition during wound healing.
Hypoxia macrophage-derived exosomal miR-26b-5p targeting PTEN promotes the development of keloids.
The long noncoding RNA MIR4435-2HG enhances the migration, promotion, and glycolysis of nonsmall cell lung cancer cells by targeting the miR-371a-5p/SOX2/PI3K/Akt axis.
Intermittent protein restriction before but not after the onset of diabetic kidney disease attenuates disease progression in mice.
Circ_0007386 Promotes the Progression of Hepatocellular Carcinoma Through the miR-507/ CCNT2 Axis.
The prognostic value and its relationship with immune infiltration of ACLY in clear cell renal cell carcinoma.
Cinobufacini enhances the therapeutic response of 5-Fluorouracil against gastric cancer by targeting cancer stem cells via AKT/GSK-3β/β-catenin signaling axis.
ACAT1 suppresses clear cell renal cell carcinoma progression by AMPK mediated fatty acid metabolism.
ETV4 promotes the progression of cholangiocarcinoma by regulating glycolysis via the TGF-β signaling.
TTYH3 Promotes Cervical Cancer Progression by Activating the Wnt/β-Catenin Signaling Pathway.
HIF-1α and adaptor protein LIM and senescent cell antigen-like domains protein 1 axis promotes tubulointerstitial fibrosis by interacting with vimentin in angiotensin II-induced hypertension.
Mefunidone alleviates silica-induced inflammation and fibrosis by inhibiting the TLR4-NF-κB/MAPK pathway and attenuating pyroptosis in murine macrophages.
Daphnetin induces ferroptosis in ovarian cancer by inhibiting NAD(P)H:Quinone oxidoreductase 1 (NQO1).
PRM1201 effectively inhibits colorectal cancer metastasis via shaping gut microbiota and short- chain fatty acids.
Mechanism of Zhenwu Decoction modulating TLR4/NF-κB/HIF-1α loop through miR-451 to delay renal fibrosis in type 2 CRS.
KDM1A, a potent and selective target, for the treatment of DNMT3A-deficient non-small cell lung cancer.
GelMA loaded with exosomes from human minor salivary gland organoids enhances wound healing by inducing macrophage polarization.
Mitochondrial dysfunction-associated alveolar epithelial senescence is involved in CdCl(2)-induced COPD-like lung injury.
BUB1 induces AKT/mTOR pathway activity to promote EMT induction in human small cell lung cancer.
CXCL16 promotes proliferation of head and neck squamous cell carcinoma by regulating GPX1-mediated antioxidant levels.
CRABP2 promotes cell migration and invasion by activating PI3K/AKT and MAPK signalling pathways via upregulating LAMB3 in prostate cancer.
Clarithromycin attenuates airway epithelial-mesenchymal transition in ovalbumin-induced asthmatic mice through modulation of Kv1.3 channels and PI3K/Akt signaling.
E3 ubiquitin ligase BTBD3 inhibits tumorigenesis of colorectal cancer by regulating the TYRO3/Wnt/β-catenin signaling axis.
KIFC3 promotes the proliferation, migration and invasion of non-small cell lung cancer through the PI3K/AKT signaling pathway.
Activin A plays an essential role in migration and proliferation of hepatic stellate cells via Smad3 and calcium signaling.
CircSEC24B activates autophagy and induces chemoresistance of colorectal cancer via OTUB1-mediated deubiquitination of SRPX2.
FBXO11 Mediates Ubiquitination of ZEB1 and Modulates Epithelial-to-Mesenchymal Transition in Lung Cancer Cells.
Reduced syncytin-1 regulates trophoblast invasion and apoptosis in preeclampsia.
Mesenchymal stem cells in tumor microenvironment: drivers of bladder cancer progression through mitochondrial dynamics and energy production.
Da-Chai-Hu-Tang Formula inhibits the progression and metastasis in HepG2 cells through modulation of the PI3K/AKT/STAT3-induced cell cycle arrest and apoptosis.
Cigarette smoke extract induces malignant transformation and DNA damage via c-MET phosphorylation in human bronchial epithelial cells.
A novel biomarker GATM suppresses proliferation and malignancy of cholangiocarcinoma cells by modulating the JNK/c-Jun signalling pathways.
Mechanisms of Yiai Fuzheng formula in the treatment of triple-negative breast cancer based on UPLC-Q-Orbitrap-HRMS, network pharmacology, and experimental validation.
Effects and mechanisms of Polygonati Rhizoma polysaccharide on potassium oxonate and hypoxanthine-induced hyperuricemia in mice.
Design, Synthesis, and Biological Evaluation of Potent EZH2/LSD1 Dual Inhibitors for Prostate Cancer.
SQLE-a promising prognostic biomarker in cervical cancer: implications for tumor malignant behavior, cholesterol synthesis, epithelial-mesenchymal transition, and immune infiltration.
Promotion of apoptosis in melanoma cells by taxifolin through the PI3K/AKT signaling pathway: Screening of natural products using WGCNA and CMAP platforms.
Anti-cancer effects of nitazoxanide in epithelial ovarian cancer in-vitro and in-vivo.
Curcumin blunts epithelial-mesenchymal transition to alleviate invasion and metastasis of prostate cancer through the JARID1D demethylation.
METTL3-dependent m6A modification facilitates decreased endometrial decidualization via attenuation of MET in endometriosis.
miR-141-3p attenuates inflammation and oxidative stress-induced pulmonary fibrosis in ARDS via the Keap1/Nrf2/ARE signaling pathway.
The activation of adenosine monophosphate-activated protein kinase inhibits the migration of tongue squamous cell carcinoma cells by targeting Claudin-1 via epithelial-mesenchymal transition.
MIA3 promotes the degradation of GSH (glutathione) by binding to CHAC1, thereby promoting the progression of hepatocellular carcinoma.
Matrine inhibits invasion and migration of gallbladder cancer via regulating the PI3K/AKT signaling pathway.
Biomimetic nanocomplex based corneal neovascularization theranostics.
Validation of quercetin in the treatment of colon cancer with diabetes via network pharmacology, molecular dynamics simulations, and in vitro experiments.
Multi-omics analysis reveals BZW1's regulation of EMT via the Wnt pathway in lung adenocarcinoma.
IGFBP7 regulates cell proliferation and migration through JAK/STAT pathway in gastric cancer and is regulated by DNA and RNA methylation.
Regulation of Fuzheng Huayu capsule on inhibiting the fibrosis-associated hepatocellular carcinogenesis.
Cdk1/p53/p21 feedback loop mechanisms in the pathogenesis of interstitial cystitis/bladder pain syndrome.
An agonist of the adenosine A(2A) receptor, CGS21680, promotes corneal epithelial wound healing via the YAP signalling pathway.
The expression and role of SUZ12 in lung adenocarcinoma.
Targeting Neuraminidase 4 Attenuates Kidney Fibrosis in Mice.
Polymeric immunoglobulin receptor promotes Th2 immune response in the liver by increasing cholangiocytes derived IL-33: a diagnostic and therapeutic biomarker of biliary atresia.
Single-cell analysis reveals alternations between the aged and young mice prostates.
Coke oven emissions exacerbate allergic asthma by promoting ferroptosis in airway epithelial cells.
ATF4/NUPR1 axis promotes cancer cell survival and mediates immunosuppression in clear cell renal cell carcinoma.
LncRNA FEZF1-AS1 promotes pulmonary fibrosis via up-regulating EZH2 and targeting miR-200c-3p to regulate the ZEB1 pathway.
The prognostic significance of twist in pancreatic cancer and its role in cancer promotion through the regulation of the immune microenvironment and EMT mechanisms.
RHOF promotes Snail1 lactylation by enhancing PKM2-mediated glycolysis to induce pancreatic cancer cell endothelial-mesenchymal transition.
Erianin inhibits the progression of pancreatic cancer by directly targeting AKT and ASK1.
CircGNAO1 suppresses hepatocellular carcinoma progression and metastasis via sponging miR-182-5p and regulating FOXO1 expression.
Construction of an autophagy-related genes risk model as predicting prognosis: BAG1 suppresses growth of clear cell renal cell carcinoma.
SASS6 promotes tumor proliferation and is associated with TP53 and immune infiltration in lung adenocarcinoma.
MYO6 contributes to tumor progression and enzalutamide resistance in castration-resistant prostate cancer by activating the focal adhesion signaling pathway.
[Aumolertinib combined with anlotinib inhibits proliferation of non-small cell lung cancer cells by down-regulating the PI3K/AKT pathway].
Ubiquitin Ligase TRIM22 Inhibits Ovarian Cancer Malignancy via TCF4 Degradation.
Chromosome 8q24 amplification associated with human hepatocellular carcinoma predicts MYC/ZEB1/MIZ1 transcriptional regulation.
Effects of Nitric Oxide on Bladder Detrusor Overactivity through the NRF2 and HIF-1α Pathways: A Rat Model Induced by Metabolic Syndrome and Ovarian Hormone Deficiency.
Integrative Omics Uncovers Low Tumorous Magnesium Content as A Driver Factor of Colorectal Cancer.
HIF-1α knockdown suppresses breast cancer metastasis via epithelial mesenchymal transition Abrogation.
SMEK1 promotes clear cell renal cell carcinoma progression via EGFR tyrosine-kinase dependent pathway.
FAM83D promotes the progression of 4NQO-induced esophageal carcinoma via inhibiting FBWX7.
Regulation of cervical cancer via G15-mediated inhibition of G protein-coupled estrogen receptor.
NOD2 reduces the chemoresistance of melanoma by inhibiting the TYMS/PLK1 signaling axis.
Circ_0084615 promotes epithelial-mesenchymal transition-mediated tumor progression in hepatocellular carcinoma.
Liquiritigenin inhibits the migration, invasion, and EMT of prostate cancer through activating ER stress.
PM(10) dysregulates epithelial barrier function in human corneal epithelial cells that is restored by antioxidant SKQ1.
CypA/TAF15/STAT5A/miR-514a-3p feedback loop drives ovarian cancer metastasis.
NEU4-mediated desialylation enhances the activation of the oncogenic receptors for the dissemination of ovarian carcinoma.
Effects of daphnetin on the mechanism of epithelial-mesenchymal transition induced by HMGB1 in human lung adenocarcinoma cells (A549 cell line).
Data-mining-based biomarker evaluation and experimental validation of SHTN1 for bladder cancer.
Long non-coding RNA AC010457.1 promotes the growth and EMT of gastric cancer via the PI3K/AKT axis.
Novel curcumin derivatives N17 exert anti-cancer effects through the CSNK1G3/AKT axis in triple-negative breast cancer.
Dysregulated lncSNHG12 suppresses the invasion and migration of trophoblasts by regulating Dio2/Snail axis to involve in recurrent spontaneous abortion.
High glucose-induced senescence contributes to tubular epithelial cell damage in diabetic nephropathy.
Microbiota-derived succinic acid mediates attenuating effect of dietary tomato juice supplementation on steatohepatitis through enhancing intestinal barrier.
Disruption of blood-brain barrier and endothelial-to-mesenchymal transition are attenuated by Astragalus polysaccharides mediated through upregulation of ETS1 expression in experimental autoimmune encephalomyelitis.
Cancer-Associated Endocrine Cells Participate in Pancreatic Carcinogenesis.
LncRNA H19 accelerates renal fibrosis by negatively regulating the let-7b-5p/TGF-βR1/COL1A1 axis.
MTFR2 accelerates hepatocellular carcinoma mediated by metabolic reprogramming via the Akt signaling pathway.
Overexpression of microRNA-611 inhibits TGF-β-induced epithelial-mesenchymal transition and migration in lung cancer cells through MAPKAP1.
Elevated ITGA3 expression serves as a novel prognostic biomarker and regulates tumor progression in cervical cancer.
NSUN2 Promotes Head and Neck Squamous Cell Carcinoma Progression by Targeting EMT-Related Gene LAMC2 in an m(5)C-YBX1-Dependent Manner.
ZNF652 exerts a tumor suppressor role in lung cancer by transcriptionally downregulating cyclin D3.
HOXC12 promotes the invasion and migration of gastric cancer cells by upregulating SALL4 and activating Wnt/β-catenin signaling pathway.
Naringin Alleviates Intestinal Fibrosis by Inhibiting ER Stress-Induced PAR2 Activation.
Controlled release of hydrogel-encapsulated mesenchymal stem cells-conditioned medium promotes functional liver regeneration after hepatectomy in metabolic dysfunction-associated steatotic liver disease.
Nuclear translocation of SIRT4 mediates deacetylation of U2AF2 to modulate renal fibrosis through alternative splicing-mediated upregulation of CCN2.
Exacerbation of pulmonary fibrosis following acute lung injury via activin-A production by recruited alveolar macrophages.
Downregulated KLF4, induced by m6A modification, aggravates intestinal barrier dysfunction in inflammatory bowel disease.
CLIP170 enhancing FOSL1 expression via attenuating ubiquitin-mediated degradation of β-catenin drives renal cell carcinoma progression.
Epithelial differentiation of gingival mesenchymal stem cells enhances re-epithelialization for full-thickness cutaneous wound healing.
Tumor Protein D53 (TPD53): Involvement in Malignant Transformation of Low-Malignant Oral Squamous Cell Carcinoma Cells.
Intravenous injection of BMSCs modulate tsRNA expression and ameliorate lung remodeling in COPD mice.
DsbA-L activates TGF-β1/SMAD3 signaling and M2 macrophage polarization by stimulating AKT1 and NLRP3 to promote pulmonary fibrosis.
The role of disulfidptosis-associated LncRNA-LINC01137 in Osteosarcoma Biology and its regulatory effects on macrophage polarization.
Methionine deprivation inhibits glioma proliferation and EMT via the TP53TG1/miR-96-5p/STK17B ceRNA pathway.
Arginine methylation-dependent TRIM47 stability mediated by CARM1 promotes the metastasis of hepatocellular carcinoma.
Effect and underlying mechanism of a photochemotherapy dual-function nanodrug delivery system for head and neck squamous cell carcinoma.
LncRNA AP001007 protects human renal tubular epithelial HK-2 cells and kidney organoids from LPS-induced injury.
PLGA microspheres carrying EMSCs-CM for the effective treatment of murine ulcerative colitis.
Role of HDAC3 in the epithelial-mesenchymal transition of retinal pigment epithelium cells: Implications for proliferative vitreoretinopathy.
FXR deficiency induced ferroptosis via modulation of the CBP-dependent p53 acetylation to suppress breast cancer growth and metastasis.
Pancreatic cancer-derived exosomal miR-510 promotes macrophage M2 polarization and facilitates cancer cell aggressive phenotypes.
Unconjugated bilirubin promotes uric acid restoration by activating hepatic AMPK pathway.
Prohibitin 2 confers NADPH oxidase 1-mediated cytosolic oxidative signaling to promote gastric cancer progression by ERK activation.
TRAIP suppressed apoptosis and cell cycle to promote prostate cancer proliferation via TRAF2-PI3K-AKT pathway activation.
NPAS2, transcriptionally activated by ARRB1, promotes the malignant behaviours of lung adenocarcinoma cells and regulates the reprogramming of glucose metabolism.
Synergistic anticancer effects of ginsenoside CK and gefitinib against gefitinib-resistant NSCLC by regulating the balance of angiogenic factors through HIF-1α/VEGF.
microRNA-141-3p Suppressed the Progression of the Clear Cell Renal Cell Carcinoma by Targeting Transforming Growth Factor Beta 2 Gene Expression.
Protein regulator of cytokinesis 1 accentuates cholangiocarcinoma progression via mTORC1-mediated glycolysis.
AMBRA1 promotes intestinal inflammation by antagonizing PP4R1/PP4c mediated IKK dephosphorylation in an autophagy-independent manner.
The Jagged-1/Notch1 Signaling Pathway Promotes the Construction of Tissue-Engineered Heart Valves.
YTHDF1 promotes gallbladder cancer progression via post-transcriptional regulation of the m6A/UHRF1 axis.
Circular RNA hsa_circ_0094976 modulates GPR155 to inhibit gastric adenocarcinoma malignant characteristics by targeting miR-223-3p.
Daurisoline suppress glioma progression by inhibiting autophagy through PI3K/AKT/mTOR pathway and increases TMZ sensitivity.
The circadian clock gene, BMAL1, promotes radiosensitization in nasopharyngeal carcinoma by inhibiting the epithelial-to-mesenchymal transition via the TGF-β1/Smads/Snail1 axis.
Riboflavin protects against pancreatic cancer metastasis by targeting TGF-β receptor 1.
Paris polyphylla ethanol extract and polyphyllin I ameliorate adenomyosis by inhibiting epithelial-mesenchymal transition.
Machine learning combined with single-cell analysis reveals predictive capacity and immunotherapy response of T cell exhaustion-associated lncRNAs in uterine corpus endometrial carcinoma.
SOAT1 regulates cholesterol metabolism to induce EMT in hepatocellular carcinoma.
β-catenin turnover is regulated by Nek10-mediated tyrosine phosphorylation in A549 lung adenocarcinoma cells.
Modified Lichong decoction intervenes in colorectal cancer by modulating the intestinal flora and the Wnt/β-catenin signaling pathway.
Design, synthesis and evaluation of a pyrazolo[3,4-d]pyrimidine derivative as a novel and potent TGFβ1R1 inhibitor.
Human amnion mesenchymal stem cells promote endometrial repair via paracrine, preferentially than transdifferentiation.
CD112 is an epithelial-to-mesenchymal transition-related and immunological biomarker in pan-cancer.
Integrated network pharmacology and experimental verification to explore the potential mechanism of San Ying decoction for treating triple-negative breast cancer.
miR-1202 regulates BPH-1 cell proliferation, apoptosis, and epithelial-to-mesenchymal transition through targeting HMGCL.
Astragalus polysaccharides augment BMSC homing via SDF-1/CXCR4 modulation: a novel approach to counteract peritoneal mesenchymal transformation and fibrosis.
Exosomal circPOLQ promotes macrophage M2 polarization via activating IL-10/STAT3 axis in a colorectal cancer model.
Methylation-regulated tumor suppressor gene PDE7B promotes HCC invasion and metastasis through the PI3K/AKT signaling pathway.
Targeting the HSP47-collagen axis inhibits brain metastasis by reversing M2 microglial polarization and restoring anti-tumor immunity.
The role of USP7-YY1 interaction in promoting colorectal cancer growth and metastasis.
IL-1β promotes esophageal squamous cell carcinoma growth and metastasis through FOXO3A by activating the PI3K/AKT pathway.
JAM3 promotes cervical cancer metastasis by activating the HIF-1α/VEGFA pathway.
E3 ubiquitin ligase UBR5 promotes gemcitabine resistance in pancreatic cancer by inducing O-GlcNAcylation-mediated EMT via destabilization of OGA.
MAP7 drives EMT and cisplatin resistance in ovarian cancer via wnt/β-catenin signaling.
IL-6 regulates epithelial ovarian cancer EMT, invasion, and metastasis by modulating Let-7c and miR-200c through the STAT3/HIF-1α pathway.
Loss of KLF15 impairs endometrial receptivity by inhibiting EMT in endometriosis.
lncRNA CERS6-AS1 upregulates the expression of ANLN by sponging miR-424-5p to promote the progression and drug resistance of lung adenocarcinoma.
Oral infection with Porphyromonas gingivalis augmented gingival epithelial barrier molecules alteration with aging.
Curcumin inhibits the invasion and migration of pancreatic cancer cells by upregulating TFPI-2 to regulate ERK- and JNK-mediated epithelial-mesenchymal transition.
NLRP3 inflammasome mediates abnormal epithelial regeneration and distal lung remodeling in silica‑induced lung fibrosis.
PSMD12 promotes non-small cell lung cancer progression through activating the Nrf2/TrxR1 pathway.
Establishment and characterization of a novel hypopharyngeal squamous cell carcinoma cell line CZH1 with genetic abnormalities.
CD74-ROS1 L2026M mutant enhances autophagy through the MEK/ERK pathway to promote invasion, metastasis and crizotinib resistance in non-small cell lung cancer cells.
Osteopontin-driven partial epithelial-mesenchymal transition governs the development of middle ear cholesteatoma.
RSK4 promotes the macrophage recruitment and M2 polarization in esophageal squamous cell carcinoma.
MBIP promotes ESCC metastasis by activating MAPK pathway.
CD146(+)CAFs promote progression of endometrial cancer by inducing angiogenesis and vasculogenic mimicry via IL-10/JAK1/STAT3 pathway.
DOCK1 regulates the malignant biological behavior of endometrial cancer through c-Raf/ERK pathway.
Mechanisms of vemurafenib-induced anti-tumor effects in ATC FRO cells.
Metformin alleviates junctional epithelium senescence via the AMPK/SIRT1/autophagy pathway in periodontitis induced by hyperglycemia.
Long non-coding RNA LINC01554 overexpression suppresses viability, migration, and invasion of liver cancer cells through regulating miR-148b-3p/EIF4E3.
Multi-omics cluster defines the subtypes of CRC with distinct prognosis and tumor microenvironment.
ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells.
PELI1: key players in the oncogenic characteristics of pancreatic Cancer.
IGF2BP3 prevent HMGB1 mRNA decay in bladder cancer and development.
Identification of host protein ENO1 (alpha-enolase) interacting with Cryptosporidium parvum sporozoite surface protein, Cpgp40.
PDE12 disrupts mitochondrial oxidative phosphorylation and mediates mitochondrial dysfunction to induce oral mucosal epithelial barrier damage in oral submucous fibrosis.
RNA modification-related genes illuminate prognostic signature and mechanism in esophageal squamous cell carcinoma.
Rare flavanone-diarylheptanoid hybrids from Typha angustifolia shows anti breast cancer activity via activating TGF-β1/Smad signaling pathway.
Cancer-associated fibroblast-secreted FGF7 as an ovarian cancer progression promoter.
Pro-tumorigenic activity of PYCR1 in gastric cancer through regulating the PI3K/AKT signaling.
SARS-CoV-2 remodels the Golgi apparatus to facilitate viral assembly and secretion.
The circRNA hsa-circ-0013561 regulates head and neck squamous cell carcinoma development via the miR-7-5p/PDK3 axis.
PPP2R1B abolishes colorectal cancer liver metastasis and sensitizes Oxaliplatin by inhibiting MAPK/ERK signaling pathway.
OTUD4 promotes the progression of glioblastoma by deubiquitinating CDK1 and activating MAPK signaling pathway.
Influenza A virus infection disrupts the function of syncytiotrophoblast cells and contributes to adverse pregnancy outcomes.
Downregulation of HIGD1B induces mitochondria-mediated apoptosis in gastric cancer cells by inactivating Akt and ERK pathways.
ID2 promotes tumor progression and metastasis in thyroid cancer.
Effect of CHRDL1 on angiogenesis and metastasis of colorectal cancer cells via TGF-β/VEGF pathway.
Increased FGL1 Expression Predicts Poor Prognosis and Promotes EMT in Head and Neck Squamous Cell Carcinoma.
MYEOV with High Frequencies of Mutations in Head and Neck Cancers Facilitates Cancer Cell Malignant Behaviors.
Tweety homolog 3 promotes colorectal cancer progression through mutual regulation of histone deacetylase 7.
SLC11A1 promotes kidney renal clear cell carcinoma (KIRC) progression by remodeling the tumor microenvironment.
Cysteine and glycine-rich protein 2 is crucial for maintaining the malignant phenotypes of gliomas through its action on Notch signalling cascade.
Exploring the regulatory role of FBXL19-AS1 in triple-negative breast cancer through the miR-378a-3p/OTUB2 axis.
A novel mitochondrial unfolded protein response-related risk signature to predict prognosis, immunotherapy and sorafenib sensitivity in hepatocellular carcinoma.
Amentoflavone reverses epithelial-mesenchymal transition in hepatocellular carcinoma cells by targeting p53 signalling pathway axis.
Eosinophil peroxidase promotes bronchial epithelial cells to secrete asthma-related factors and induces the early stage of airway remodeling.
Lysophosphatidic acid promotes ESCC progression by increasing the level of CCL2 secreted by esophageal epithelial cells.
IFNT-induced IRF1 enhances bovine endometrial receptivity by transactivating LIFR.
Hypoxia differently regulates the proportion of ALDH(hi) cells in lung squamous carcinoma H520 and adenocarcinoma A549 cells via the Wnt/β-catenin pathway.
Panax notoginseng saponins improve oral submucous fibrosis by inhibiting the Wnt/β-catenin signal pathway.
Hsa_circ_0004214 involved in the epithelial-mesenchymal transition induced by beryllium sulfate through modulating JAK-STAT signaling pathway.
Glucose regulates the HMGB1 signaling pathway through SIRT1 in glioma.
Peptide Transporter 1-Mediated Dipeptide Transport Promotes Hepatocellular Carcinoma Metastasis by Activating MAP4K4/G3BP2 Signaling Axis.
Mortalin promotes the evolution of androgen-independent prostate cancer through Wnt/β-catenin signaling pathway.
POLR1D silencing suppresses lung cancer cells proliferation and migration via inhibition of PI3K-Akt pathway.
Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1-ZEB1 Axis-Mediated Epithelial-Mesenchymal Transition.
Analysis of cell death-related genes to evaluate the prognostic and immunotherapeutic value in bladder cancer.
Extracellular vesicles activated cancer-associated fibroblasts promote lung cancer metastasis through mitophagy and mtDNA transfer.
IFI16 promotes the progression of clear cell renal cell carcinoma through the IL6/PI3K/AKT axis.
ISG15 promotes tumor progression via IL6/JAK2/STAT3 signaling pathway in ccRCC.
NAT1 inhibits liver metastasis of colorectal cancer by regulating EMT and glycolysis.
DNAJC1 facilitates glioblastoma progression by promoting extracellular matrix reorganization and macrophage infiltration.
Repurposing homoharringtonine for thyroid cancer treatment through TIMP1/FAK/PI3K/AKT signaling pathway.
Supramolecular artificial Nano-AUTACs enable tumor-specific metabolism protein degradation for synergistic immunotherapy.
Association of mitochondrial phosphoenolpyruvate carboxykinase with prognosis and immune regulation in hepatocellular carcinoma.
Calpain 8 as a potential biomarker regulates the progression of pancreatic cancer via EMT and AKT/ERK pathway.
Bidirectional effects of the tryptophan metabolite indole-3-acetaldehyde on colorectal cancer.
SIAH2 is specifically expressed during cervical carcinogenesis, and closely relates to the abnormal proliferation of cervical epithelial cells.
Baicalein promotes KDM4E to induce BICD1 and inhibit triple-negative breast cancer progression by blocking PAR1 signaling.
Parkin deficiency promotes liver cancer metastasis by TMEFF1 transcription activation via TGF-β/Smad2/3 pathway.
The inhibition of MARCO by PolyG alleviates pulmonary fibrosis via regulating mitochondrial function in a silicotic rat model.
MicroRNA-505-3p mediates cell motility of epithelial ovarian cancer via suppressing PEAK1 expression.
Therapeutic potential of vitamin D3 in mitigating high glucose‑induced renal damage: Mechanistic insights into oxidative stress inhibition and TXNIP/NLRP3 signaling pathway blockade.
Fibroblast growth factor 21 alleviates idiopathic pulmonary fibrosis by inhibiting PI3K-AKT-mTOR signaling and stimulating autophagy.
Hypericin-mediated photodynamic therapy inhibits metastasis and EMT of colorectal cancer cells by regulating RhoA-ROCK1 signaling pathway.
Grifolin Induces Cell Death of Human Lung Cancer A549 Cell Line via Inhibiting KRAS-Mediated Multiple Signaling Pathways.
Cryptochrome 2 Suppresses Epithelial-Mesenchymal Transition by Promoting Trophoblastic Ferroptosis in Unexplained Recurrent Spontaneous Abortion.
Triterpenoids with α-glucosidase inhibitory and cytotoxic activities from the fruits of Schisandra chinensis.
LncRNA AC100826.1 regulated PLCB1 to promote progression in non-small cell lung cancer.
LINC00460 promotes neuroblastoma tumorigenesis and cisplatin resistance by targeting miR-149-5p/DLL1 axis and activating Notch pathway in vitro and in vivo.
Baohuoside I chemosensitises breast cancer to paclitaxel by suppressing extracellular vesicle/CXCL1 signal released from apoptotic cells.
The EPRS-ATF4-COLI pathway axis is a potential target for anaplastic thyroid carcinoma therapy.
Celastrol mediates CAV1 to attenuate pro-tumorigenic effects of senescent cells.
Mechanism of Nicotiflorin in San-Ye-Qing rhizome for anti-inflammatory effect in ulcerative colitis.
Targeting the PI3K/AKT/mTOR pathway offer a promising therapeutic strategy for cholangiocarcinoma patients with high doublecortin-like kinase 1 expression.
SEC61 translocon gamma subunit is correlated with glycolytic activity, epithelial mesenchymal transition and the immune suppressive phenotype of lung adenocarcinoma.
New advances of NG2-expressing cell subset in marrow mesenchymal stem cells as novel therapeutic tools for liver fibrosis/cirrhosis.
Echistatin/BYL-719 impedes epithelial-mesenchymal transition in pulmonary fibrosis induced by silica through modulation of the Integrin β1/ILK/PI3K signaling pathway.
Immunohistochemistry identifies E-cadherin, N-cadherin and focal adhesion kinase (FAK) as predictors of stage I non-small cell lung carcinoma spread through the air spaces (STAS), and the combinations as prognostic factors.
SIPA1 promotes epithelial-mesenchymal transition in colorectal cancer through STAT3 activation.
Fabrication of heterocellular spheroids with controllable core-shell structure using inertial focusing effect for scaffold-free 3D cell culture models.
Construction of the pulmonary bio-adhesive delivery system of nintedanib nanocrystalline for effective treatment of pulmonary fibrosis.
Alpha 1,3 N-Acetylgalactosaminyl Transferase (GTA) Impairs Invasion Potential of Trophoblast Cells in Preeclampsia.
Relaxin combined with transarterial chemoembolization achieved synergistic effects and inhibited liver cancer metastasis in a rabbit VX2 model.
m6A-Mediated IRS1 Regulates the Development of Oral Squamous Cell Carcinoma through p53/Line-1 Signaling.
Fasudil attenuates oxidative stress-induced partial epithelial-mesenchymal transition of tubular epithelial cells in hyperuricemic nephropathy via activating Nrf2.
DNA demethylase TET2-mediated reduction of HADHB expression contributes to cadmium-induced malignant progression of colorectal cancer.
A recombinant IL-1β vaccine attenuates bleomycin-induced pulmonary fibrosis in mice.
Attenuated Salmonella typhimurium L forms suppress tumor growth and promote apoptosis in murine ovarian tumors.
LINC01133 promotes pancreatic ductal adenocarcinoma epithelial-mesenchymal transition mediated by SPP1 through binding to Arp3.
LRP1 induces anti-PD-1 resistance by modulating the DLL4-NOTCH2-CCL2 axis and redirecting M2-like macrophage polarisation in bladder cancer.
SLC7A11 promotes EMT and metastasis in invasive pituitary neuroendocrine tumors by activating the PI3K/AKT signaling pathway.
Distinguished biomimetic dECM system facilitates early detection of metastatic breast cancer cells.
CHMP3 promotes the progression of hepatocellular carcinoma by inhibiting caspase‑1‑dependent pyroptosis.
PKMYT1 induced by YAP/TEAD1 gives rise to the progression and worse prognosis of bladder cancer.
Circ-SATB2 (hsa_circ_0008928) and miR-150-5p are regulators of TRIM66 in the regulation of NSCLC cell growth and metastasis of NSCLC cells via the ceRNA pathway.
MicroRNA-10a-5p-mediated downregulation of GATA6 inhibits tumor progression in ovarian cancer.
Nucleoporin 93, a new substrate of the E3 ubiquitin protein ligase HECTD1, promotes esophageal squamous cell carcinoma progression.
Spatiotemporally sequential delivery of biomimetic liposomes potentiates glioma chemotherapy.
Hematoporphyrin derivative photodynamic therapy induces apoptosis and suppresses the migration of human esophageal squamous cell carcinoma cells by regulating the PI3K/AKT/mTOR signaling pathway.
Chitosan-based oral nanoparticles as an efficient platform for kidney-targeted drug delivery in the treatment of renal fibrosis.
17β-Estradiol mediates TGFBR3/Smad2/3 signaling to attenuate the fibrosis of TGF-β1-induced bovine endometrial epithelial cells via GPER.
The homologous tumor-derived-exosomes loaded with miR-1270 selectively enhanced the suppression effect for colorectal cancer cells.
Ligustilide prevents thymic immune senescence by regulating Thymosin β15-dependent spatial distribution of thymic epithelial cells.
Hsa_circ_0013561 promotes progression of nasopharyngeal carcinoma by activating JAK2/STAT3 signaling pathway.
Two-dimensional vascularized liver organoid on extracellular matrix with defined stiffness for modeling fibrotic and normal tissues.
Hsa_circ_0081065 exacerbates IH-induced EndMT via regulating miR-665/HIF-1α signal axis and HIF-1α nuclear translocation.
Serine/threonine kinase 36 induced epithelial-mesenchymal transition promotes docetaxel resistance in prostate cancer.
TMCO1 regulates cell proliferation, metastasis and EMT signaling through CALR, promoting ovarian cancer progression and cisplatin resistance.
Lactate accumulation induced by Akt2-PDK1 signaling promotes pulmonary fibrosis.
Downregulation of Roundabout guidance receptor 2 suppresses hepatocellular carcinoma progression by interacting with Y-box binding protein 1.
Sinensetin suppresses breast cancer cell progression via Wnt/β-catenin pathway inhibition.
Phthalides from the rhizome of Ligusticum chuanxiong Hort. attenuate diabetic nephropathy in mice.
Quercetin inhibits mesothelial-mesenchymal transition and alleviates postoperative peritoneal adhesions by blocking the TGF-β1/PI3K/AKT pathway.
HIF-1A as a prognostic biomarker related to invasion, migration and immunosuppression of cervical cancer.
Transcription factor FOXP4 inversely governs tumor suppressor genes and contributes to thyroid cancer progression.
Dexmedetomidine ameliorates high glucose-induced epithelial-mesenchymal transformation in HK-2 cells through the Cdk5/Drp1/ROS pathway.
Nicotinamide mononucleotide attenuates airway epithelial barrier dysfunction via inhibiting SIRT3 SUMOylation in asthma.
FBXO28 promotes cell proliferation, migration and invasion via upregulation of the TGF-beta1/SMAD2/3 signaling pathway in ovarian cancer.
Circular RNA DNAH14 molecular mechanism in an experimental model of hepatocellular carcinoma treated with Cobalt chloride to mimic the hypoxia-like response of transcatheter arterial chemoembolization.
ERH gene knockdown inhibits the proliferation and migration of ARPE-19 cells through MCM complex and EMT process.
A Platform for Testing the Biocompatibility of Implants: Silicone Induces a Proinflammatory Response in a 3D Skin Equivalent.
DDX60 Promotes Migration and Invasion of Head and Neck Squamous Cell Carcinoma Cell through the NF-κB/IFI27 Signaling Pathway.
Thymosin β4 Regulates the Differentiation of Thymocytes by Controlling the Cytoskeletal Rearrangement and Mitochondrial Transfer of Thymus Epithelial Cells.
A transcriptome based molecular classification scheme for cholangiocarcinoma and subtype-derived prognostic biomarker.
Rehmannia glutinosa Libosch and Cornus officinalis Sieb herb couple ameliorates renal interstitial fibrosis in CKD rats by inhibiting the TGF-β1/MAPK signaling pathway.
Tumor-associated macrophage-derived exosomal miR-513b-5p is a target of jianpi yangzheng decoction for inhibiting gastric cancer.
Panax notoginseng saponin alleviates pulmonary fibrosis in rats by modulating the renin-angiotensin system.
Metabolomics study reveals increased deoxycholic acid contributes to deoxynivalenol-mediated intestinal barrier injury.
The Microbial Tryptophan Metabolite Contributes to the Remission of Salmonella typhimurium Infection in Mice.
Identification of MDK as a Hypoxia- and Epithelial-Mesenchymal Transition-Related Gene Biomarker of Glioblastoma Based on a Novel Risk Model and In Vitro Experiments.
Cold atmospheric plasma sensitizes head and neck cancer to chemotherapy and immune checkpoint blockade therapy.
Melatonin decreases GSDME mediated mesothelial cell pyroptosis and prevents peritoneal fibrosis and ultrafiltration failure.
Circular RNA Dipeptidyl Peptidase 4 (circDPP4) Stimulates the Expression of Glutamate Dehydrogenase 1 to Contribute to the Malignant Phenotypes of Prostate Cancer by Sponging miR-497-5p.
NMI promotes tumor progression and gemcitabine resistance in pancreatic cancer via STAT3-IFIT3 axis.
Spindle and kinetochore-related complex subunit 3 has a protumour function in osteosarcoma by activating the Notch pathway.
Exosomal circ_0037104 derived from Hu-MSCs inhibits cholangiocarcinoma progression by sponging miR-620 and targeting AFAP1.
Icariside II prevents kidney fibrosis development in chronic kidney disease by promoting fatty acid oxidation.
Serabelisib regulates GSDMD-mediated pyroptosis, apoptosis and migration of hepatoma cells via the PI3K/Akt/E-cadherin signaling pathway.
Promoting effect and immunologic role of secretogranin II on bladder cancer progression via regulating MAPK and NF-κB pathways.
Exosome-delivered miR-410-3p reverses epithelial-mesenchymal transition, migration and invasion of trophoblasts in spontaneous abortion.
Bone morphogenetic protein 4 thermosensitive hydrogel inhibits corneal neovascularization by repairing corneal epithelial apical junctional complexes.
GK921, a transglutaminase inhibitor, strengthens the antitumor effect of cisplatin on pancreatic cancer cells by inhibiting epithelial-to-mesenchymal transition.
Downregulation of TET2 Contributes to Nasal Polypogenesis Through Hypoxia-Inducible Factor 1α-Mediated Epithelial-to-Mesenchymal Transition.
GIMAP7 inhibits epithelial-mesenchymal transition and glycolysis in lung adenocarcinoma cells via regulating the Smo/AMPK signaling pathway.
Ginsenoside Rk3 modulates gut microbiota and regulates immune response of group 3 innate lymphoid cells to against colorectal tumorigenesis.
Tumor suppressor miR-361-3p inhibits prostate cancer progression through Gli1 and AKT/mTOR signaling pathway.
MPDZ is associated with immune infiltration and regulates migration and invasion by switching YAP1 phosphorylation in colorectal cancer.
Luteolin blocks the ROS/PI3K/AKT pathway to inhibit mesothelial-mesenchymal transition and reduce abdominal adhesions.
Interaction between Wnt/β-catenin signaling pathway and EMT pathway mediates the mechanism of sunitinib resistance in renal cell carcinoma.
SMG9 is a novel prognostic-related biomarker in glioma correlating with ferroptosis and immune infiltrates.
Bufei Yishen formula protects the airway epithelial barrier and ameliorates COPD by enhancing autophagy through the Sirt1/AMPK/Foxo3 signaling pathway.
SLC25A17 inhibits autophagy to promote triple-negative breast cancer tumorigenesis by ROS-mediated JAK2/STAT3 signaling pathway.
The miR-1290/OGN axis in ovarian cancer-associated fibroblasts modulates cancer cell proliferation and invasion.
Novel prognostic marker TGFBI affects the migration and invasion function of ovarian cancer cells and activates the integrin αvβ3-PI3K-Akt signaling pathway.
m6A-methylated KCTD21-AS1 regulates macrophage phagocytosis through CD47 and cell autophagy through TIPR.
LINC02561 promotes metastasis in HCC via HIF1-α/NDRG1/UPF1 axis.
miR-34c-5p inhibited fibroblast proliferation, differentiation and epithelial-mesenchymal transition in benign airway stenosis via MDMX/p53 pathway.
Crosstalk between KDEL receptor and EGF receptor mediates cell proliferation and migration via STAT3 signaling.
LncRNA RPARP-AS1 promotes the progression of osteosarcoma cells through regulating lipid metabolism.
The clustering status of detached gastric cancer cells inhibits anoikis-induced ferroptosis to promote metastatic colonization.
Investigating HMGB1 as a potential serum biomarker for early diabetic nephropathy monitoring by quantitative proteomics.
YTHDF2-mediated circYAP1 drives immune escape and cancer progression through activating YAP1/TCF4-PD-L1 axis.
Calcitriol promotes M2 polarization of tumor-associated macrophages in 4T1 mouse mammary gland cancer via the induction of proinflammatory cytokines.
ZNF460-mediated circRPPH1 promotes TNBC progression through ITGA5-induced FAK/PI3K/AKT activation in a ceRNA manner.
Icariin Regulates EMT and Stem Cell-Like Character in Breast Cancer through Modulating lncRNA NEAT1/TGFβ/SMAD2 Signaling Pathway.
Bromodomain containing 4 inhibition combats gastric precancerous lesions via modulating macrophage polarization.
Up-regulation of long non-coding RNA H19 ameliorates renal tubulointerstitial fibrosis by reducing lipid deposition and inflammatory response through regulation of the microRNA-130a-3p/long-chain acyl-CoA synthetase 1 axis.
Therapeutic potential of Lacticaseibacillus rhamnosus grx10 and its derived postbiotic through gut microbiota and MAPK/MLCK/MLC pathway-mediated intestinal barrier repairment in ulcerative colitis.
RSL3 sensitizes glioma cells to ionizing radiation by suppressing TGM2-dependent DNA damage repair and epithelial-mesenchymal transition.
CircRNA ITCH Inhibits Epithelial-Mesenchymal Transformation and Promotes Apoptosis in Papillary Thyroid Carcinoma via miR-106a-5p/JAZF1 Axis.
Tabersonine enhances cisplatin sensitivity by modulating Aurora kinase A and suppressing epithelial-mesenchymal transition in triple-negative breast cancer.
Unraveling the mechanisms of RECQL4-mediated cervical cancer progression through the PI3K/AKT pathway.
Establishment and optimization of a novel mouse model of hyperuricemic nephropathy.
TXNIP deficiency attenuates renal fibrosis by modulating mTORC1/TFEB-mediated autophagy in diabetic kidney disease.
Adaptor protein CEMIP reduces the chemosensitivity of small cell lung cancer via activation of an SRC-YAP oncogenic module.
M6A RNA Methylation-Mediated TUG1 Stability Maintains Mitochondrial Homeostasis during Kidney Aging by Epigenetically Regulating PGC1-α Expression.
Mediation of circ_0007142 on miR-128-3p/S100A14 pathway to stimulate the progression of cervical cancer.
Increased UBD Is a Potential Diagnostic and Prognostic Biomarker in Glioma.
Dihydroartemisinin enhances the anti-tumour effect of photodynamic therapy by targeting PKM2-mediated glycolysis in oesophageal cancer cell.
Baicalein inhibits cell proliferation and induces apoptosis in brain glioma cells by downregulating the LGR4-EGFR pathway.
PH-sensitive adriamycin hydrochloride and oxaliplatin dual-loaded microspheres synergistically enhance local injections effect of hepatocellular carcinoma.
AOPPs induces EMT and fibrosis by activating oxidative stress through ERK/p38 MAPK signaling pathway in endometriosis.
Activation of ferritin light chain (FTL) by transcription factor salmonella pathogenicity island 1 modulates glycolysis to drive metastasis of ovarian cancer cells.
Critical role of apoptosis in MeCP2-mediated epithelial-mesenchymal transition of ARPE-19 cells.
Quercetin inhibits malignant progression of high metastatic advanced colon cancer in hypoxia via suppressing ROS and PI3K/AKT pathway.
Sec13 promotes glycolysis by inhibiting Ubqln1 mediated Pgm1 ubiquitination in ALI.
Hypoxia-driven heterogeneous expression of α5 integrin in glioblastoma stem cells is linked to HIF-2α.
Sodium cromoglycate exerts anti-pulmonary fibrosis effects by targeting the Keap1 protein to activate Nrf2 signaling.
Suyin Detoxification Granule alleviates trimethylamine N-oxide-induced tubular ferroptosis and renal fibrosis to prevent chronic kidney disease progression.
Jia Wei Qingxin Lotus Seed Drink ameliorates epithelial mesenchymal transition injury in diabetic kidney disease via inhibition of JMJD1C/SP1/ZEB1 signaling pathway.
Corynoxine exerts the anti-tumor effect on esophageal squamous cell carcinoma principally via the EZH2-DUSP5-ERK1/2-mediated cell growth inhibition.
Targeting and degradation of OTUB1 by Erianin for antimetastasis in esophageal squamous cell carcinoma.
FAM3C Regulates Glioma Cell Proliferation, Invasion, Apoptosis, and Epithelial Mesenchymal Transition via the Notch Pathway.
Quercetin prevents the USP22-Snail1 signaling pathway to ameliorate diabetic tubulointerstitial fibrosis.
Mechanistic study of quercetin in the treatment of hepatocellular carcinoma with diabetes via MEK/ERK pathway.
Activin A inhibits the migration of human lung adenocarcinoma A549 cells induced by EGF.
Bone morphogenetic protein 4 inhibits corneal neovascularization by blocking NETs-induced disruption to corneal epithelial barrier.
Serine related gene CCT6A promotes metastasis of hepatocellular carcinoma via interacting with RPS3.
Tripartite motif-containing protein 50 suppresses triple-negative breast cancer progression by regulating the epithelial-mesenchymal transition.
MiR-135b-5p promotes cetuximab resistance in colorectal cancer by regulating FOXN3.
RND1 inhibits epithelial-mesenchymal transition and temozolomide resistance of glioblastoma via AKT/GSK3-β pathway.
DNMT1-driven methylation of RORA facilitates esophageal squamous cell carcinoma progression under hypoxia through SLC2A3.
Macropinocytosis inhibits alkaliptosis in pancreatic cancer cells through fatty acid uptake.
Chromatin licensing and DNA replication factor 1 as a potential prognostic and diagnostic biomarker for gastric cancer.
GPR37-enhanced ubiquitination of ATP1A1 inhibits tumor progression and radiation resistance in esophageal squamous cell carcinoma.
CTSG is a prognostic marker involved in immune infiltration and inhibits tumor progression though the MAPK signaling pathway in non-small cell lung cancer.
METTL14 downregulates GLUT9 through m6A methylation and attenuates hyperuricemia-induced fibrosis in mouse renal tubular epithelial cells.
Identification of UNC5B as a novel aggressive biomarker for osteosarcoma based on basement membrane genes.
ANGPTL4 mediated mesothelial-mesenchymal transition in pulmonary fibrosis: a potential therapeutic target.
Exosomes containing circSCP2 in colorectal cancer promote metastasis via sponging miR-92a-1-5p and interacting with PTBP1 to stabilize IGF2BP1.
Roles of gut microbiome-associated metabolites in pulmonary fibrosis by integrated analysis.
Machine learning-based prognostic model of lactylation-related genes for predicting prognosis and immune infiltration in patients with lung adenocarcinoma.
miR-3191 promotes the proliferation and metastasis of hepatocellular carcinoma via regulating PAK6.
Elaiophylin targets EIF4B to suppress the growth of esophageal squamous cell carcinoma via the PI3K/AKT signaling pathway.
Inhibition of AhR disrupts intestinal epithelial barrier and induces intestinal injury by activating NF-κB in COPD.
Has_circ_0002360 facilitates immune evasion by enhancing heterogeneous nuclear ribonucleoprotein A1 stability, thereby promoting malignant progression in non-small cell lung cancer.
Nicotinamide protects against diabetic kidney disease through regulation of Sirt1.
Long non-coding RNA H19 mediates the miR-29b/transforming growth factor-β1/Drosophila mothers against decapentaplegic 3 signalling pathway to promote bladder fibrosis in diabetic rats.
Dexmedetomidine promotes colorectal cancer progression via Piwil2 signaling.
IFIT1 modulates the proliferation, migration and invasion of pancreatic cancer cells via Wnt/β-catenin signaling.
STIL facilitates the development and malignant progression of triple-negative breast cancer through activation of Fanconi anemia pathway via interacting with KLF16.
N6-methyladenosine modified circPAK2 promotes lymph node metastasis via targeting IGF2BPs/VEGFA signaling in gastric cancer.
Autocatalytic, Brain Tumor-Targeting Delivery of Bardoxolone Methyl Self-Assembled Nanoparticles for Glioblastoma Treatment.
Role of transient receptor potential vanilloid 4 channels in an ovalbumin-induced murine food allergic model.
Biological effect of ETV4 and the underlying mechanism of its regulatory effect on epithelial‑mesenchymal transition in intrahepatic cholangiocarcinoma cells.
Exosomal miR-130b-3p suppresses metastasis of non-small cell lung cancer cells by targeting DEPDC1 via TGF-β signaling pathway.
P4HA3 promotes head and neck squamous cell carcinoma progression via the WNT/β-catenin signaling pathway.
INPP4B suppresses HER2-induced mesenchymal transition in HER2+ breast cancer and enhances sensitivity to Lapatinib.
Infection of human organoids supports an intestinal niche for Chlamydia trachomatis.
Changes in PI3K/AKT and NRF2/HO-1 signaling expression and intestinal microbiota in bleomycin-induced pulmonary fibrosis.
Anti-ulcerative colitis effect of rotating magnetic field on DSS-induced mice by modulating colonic inflammatory deterioration.
Integrated multi-omics profiling landscape of organising pneumonia.
Aloperine Suppresses Cancer Progression by Interacting with VPS4A to Inhibit Autophagosome-lysosome Fusion in NSCLC.
STC2 suppresses triple-negative breast cancer migration and invasion by inhibition on EMT and promotion on cell apoptosis.
TCF12-regulated GRB7 facilitates the HER2+ breast cancer progression by activating Notch1 signaling pathway.
Hypoxia exacerbates the malignant transformation of gastric epithelial cells induced by long-term H. pylori infection.
OTU deubiquitinase, ubiquitin aldehyde binding 2 (OTUB2) modulates the stemness feature, chemoresistance, and epithelial-mesenchymal transition of colon cancer via regulating GINS complex subunit 1 (GINS1) expression.
Capsaicin combined with cisplatin inhibits TGF-β1-induced EMT and TSCC cells migration via the Claudin-1/PI3K/AKT/mTOR signaling pathway.
A CLIC1 network coordinates matrix stiffness and the Warburg effect to promote tumor growth in pancreatic cancer.
Acetylation of PGK1 at lysine 323 promotes glycolysis, cell proliferation, and metastasis in luminal A breast cancer cells.
TRIP13 regulates progression of gastric cancer through stabilising the expression of DDX21.
RARB associated with MSI, affects progression and prognosis of gastric cancer.
Role of gut microbiota in Crohn's disease pathogenesis: Insights from fecal microbiota transplantation in mouse model.
Repurposed AT9283 triggers anti-tumoral effects by targeting MKK3 oncogenic functions in Colorectal Cancer.
FAM122A functions as a tumor suppressor in oral squamous cell carcinoma.
Matrine Suppresses Arsenic-Induced Malignant Transformation of SV-HUC-1 Cells via NOX2.
RGS10 deficiency facilitates distant metastasis by inducing epithelial-mesenchymal transition in breast cancer.
Does rAj-Tspin, a novel peptide from A. japonicus, exert antihepatocellular carcinoma effects via the ITGB1/ZYX/FAK/AKT signaling pathway?
Pt(iv) derivatives of cisplatin and oxaliplatin bearing an EMT-related TMEM16A/COX-2-selective dual inhibitor against colorectal cancer cells HCT116.
RAE1 promotes gastric carcinogenesis and epithelial-mesenchymal transition.
Kinesin Family Member-18A (KIF18A) Promotes Cell Proliferation and Metastasis in Hepatocellular Carcinoma.
The FOXO1/G6PC axis promotes gastric cancer progression and mediates 5-fluorouracil resistance by targeting the PI3K/AKT/mTOR signaling pathway.
E3 ubiquitin ligase NEDD4L inhibits epithelial-mesenchymal transition by suppressing the β-catenin/HIF-1α positive feedback loop in chronic rhinosinusitis with nasal polyps.
Bone morphogenetic protein 6 (BMP6) antagonises experimental proliferative vitreoretinopathy established by TGF-β2 stimulation in retinal pigment epithelial cells through modulation of the p38 and JNK MAPK pathways.
Propofol-induced LINC01133 inhibits the progression of colorectal cancer via miR-186-5p/NR3C2 axis.
Supramolecular Hydrogel with Ultra-Rapid Cell-Mediated Network Adaptation for Enhancing Cellular Metabolic Energetics and Tissue Regeneration.
FERMT2 upregulation in CAFs enhances EMT of OSCC and M2 macrophage polarization.
CHL1 inhibits cell proliferation, migration and invasion by regulating the NF‑κB signaling pathway in colorectal cancer.
Chloroxine inhibits pancreatic cancer progression through targeted antagonization of the PI3K/AKT/mTOR signaling pathway.
PlexinA1 promotes gastric cancer migration through preventing MICAL1 protein ubiquitin/proteasome-mediated degradation in a Rac1-dependent manner.
PI3Kδ Mediates Fibrosis by Patient-Derived Vitreous.
Fusobacterium periodonticum BCT protein targeting glucose metabolism to promote the epithelial-mesenchymal transition of esophageal cancer cells by lactic acid.
The Natural Product Secoemestrin C Inhibits Colorectal Cancer Stem Cells via p38-S100A8 Feed-Forward Regulatory Loop.
HIST3H2A promotes the progression of prostate cancer through inhibiting cell necroptosis.
RETRACTED: High PGC-1α Expression as a Poor Prognostic Indicator in Intracranial Glioma.
Tabersonine Enhances Olaparib Sensitivity through FHL1-Mediated Epithelial-Mesenchymal Transition in an Ovarian Tumor.
AKR1B10 accelerates glycolysis through binding HK2 to promote the malignant progression of oral squamous cell carcinoma.
DCDC2 inhibits hepatic stellate cell activation and ameliorates CCl(4)-induced liver fibrosis by suppressing Wnt/β-catenin signaling.
hnRNPU is required for spermatogonial stem cell pool establishment in mice.
Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome.
N6-methyladenosine-modified circSLCO1B3 promotes intrahepatic cholangiocarcinoma progression via regulating HOXC8 and PD-L1.
The NF-κB/NUAK2 signaling axis regulates pancreatic cancer progression by targeting SMAD2/3.
PRMT6-mediated transcriptional activation of ythdf2 promotes glioblastoma migration, invasion, and emt via the wnt-β-catenin pathway.
MFG-E8 induces epithelial-mesenchymal transition and anoikis resistance to promote the metastasis of pancreatic cancer cells.
hsa_circ_0007919 promotes pancreatic cancer metastasis by modulating Sp1-mediated THBS1 transcription.
JMJD3 activation contributes to renal protection and regeneration following acute kidney injury in mice.
Butyrate attenuates the stemness of lung cancer cells through lysosome Fe(2+)- and SLC7A11-mediated ferroptosis.
Hawthorn Proanthocyanidin Extract Inhibits Colorectal Carcinoma Metastasis by Targeting the Epithelial-Mesenchymal Transition Process and Wnt/β-Catenin Signaling Pathway.
Inhibition of PD-L1 expression in non-small cell lung cancer may reduce vasculogenic mimicry formation by inhibiting the epithelial mesenchymal transformation process.
Adhesive hydrogel releases protocatechualdehyde-Fe(3+) complex to promote three healing stages for accelerated therapy of oral ulcers.
CircGPC3 promotes hepatocellular carcinoma progression and metastasis by sponging miR-578 and regulating RAB7A/PSME3 expression.
Echinacoside alleviates airway remodeling and inflammation in an ovalbumin-induced neonatal mouse model of asthma by modulating the SIRT1-NF-κB pathway.
Tetrandrine Inhibits Cancer Stem Cell Characteristics and Epithelial to Mesenchymal Transition in Triple-Negative Breast Cancer via SOD1/ROS Signaling Pathway.
Chlorogenic Acid Inhibited Epithelial-Mesenchymal Transition to Treat Pulmonary Fibrosis through Modulating Autophagy.
MKRN1/2 serve as tumor suppressors in renal clear cell carcinoma by regulating the expression of p53.
Oxidative stress-induced temporal activation of ERK1/2 phosphorylates coreceptor of Wnt/β-catenin for myofibroblast formation in human lens epithelial cells.
Up-regulated SPP1 increases the risk from IPF to lung cancer via activating the pro-tumor macrophages.
The Role of Purine Metabolism-Related Genes PPAT and IMPDH1 in the Carcinogenesis of Intrahepatic Cholangiocarcinoma Based on Metabonomic and Bioinformatic Analyses.
The Interaction of Apelin and FGFR1 Ameliorated the Kidney Fibrosis through Suppression of TGFβ-Induced Endothelial-to-Mesenchymal Transition.
LncRNA SNHG5 Suppresses Cell Migration and Invasion of Human Lung Adenocarcinoma via Regulation of Epithelial-Mesenchymal Transition.
lncRNA CRNDE Affects Th17/IL-17A and Inhibits Epithelial-Mesenchymal Transition in Lung Epithelial Cells Reducing Asthma Signs.
Lnc NR2F1-AS1 Promotes Breast Cancer Metastasis by Targeting the MiR-25-3p/ZEB2 Axis.
Low Expression of GIGYF1 Inhibits Metastasis, Proliferation, and Promotes Apoptosis and Autophagy of Gastric Cancer Cells.
Renalase Prevents Renal Fibrosis by Inhibiting Endoplasmic Reticulum Stress and Down-Regulating GSK-3β/Snail Signaling.
PYGL-mediated glucose metabolism reprogramming promotes EMT phenotype and metastasis of pancreatic cancer.
Timosaponin AIII promotes non-small-cell lung cancer ferroptosis through targeting and facilitating HSP90 mediated GPX4 ubiquitination and degradation.
BGN/FAP/STAT3 positive feedback loop mediated mutual interaction between tumor cells and mesothelial cells contributes to peritoneal metastasis of gastric cancer.
System analysis identifies UBE2C as a novel oncogene target for adrenocortical carcinoma.
Caffeic acid phenethyl ester suppresses metastasis of breast cancer cells by inactivating FGFR1 via MD2.
Exosome-delivered circRPS5 inhibits the progression of melanoma via regulating the miR-151a/NPTX1 axis.
Differential effects of WRAP53 transcript variants on non-small cell lung cancer cell behaviors.
Downregulation of KIAA1199 alleviated the activation, proliferation, and migration of hepatic stellate cells by the inhibition of epithelial-mesenchymal transition.
Downregulation of RBM17 enhances cisplatin sensitivity and inhibits cell invasion in human hypopharyngeal cancer cells.
HDAC5-mediated PRAME regulates the proliferation, migration, invasion, and EMT of laryngeal squamous cell carcinoma via the PI3K/AKT/mTOR signaling pathway.
HK2 contributes to the proliferation, migration, and invasion of diffuse large B-cell lymphoma cells by enhancing the ERK1/2 signaling pathway.
Exosome-Delivered circSTAU2 Inhibits the Progression of Gastric Cancer by Targeting the miR-589/CAPZA1 Axis.
Jiawei Danxuan Koukang Alleviates Arecoline Induced Oral Mucosal Lesions: Network Pharmacology and the Combined Ultra-High Performance Liquid Chromatography (UPLC) and Mass Spectrometry (MS).
Integrating Network Pharmacology and Experimental Validation to Explore the Pharmacological Mechanism of Astragaloside IV in Treating Bleomycin-Induced Pulmonary Fibrosis.
Fucosyltransferase 5 Promotes the Proliferative and Migratory Properties of Intrahepatic Cholangiocarcinoma Cells via Regulating Protein Glycosylation Profiles.
Escherichia coli Promotes Endothelial to Mesenchymal Transformation of Liver Sinusoidal Endothelial Cells and Exacerbates Nonalcoholic Fatty Liver Disease Via Its Flagellin.
ZEB1 Transcriptionally Activates PHGDH to Facilitate Carcinogenesis and Progression of HCC.
B7 Induces Apoptosis in Colorectal Cancer Cells by Regulating the Expression of Caspase-3 and Inhibits Autophagy.
Esomeprazole Alleviates Cisplatin Resistance by Inhibiting the AKT/mTOR Pathway in Ovarian Cancer Cells.
Irisin Ameliorates Renal Tubulointerstitial Fibrosis by Regulating the Smad4/β-Catenin Pathway in Diabetic Mice.
The cancer/testis antigen HORMAD1 promotes gastric cancer progression by activating the NF-κB signaling pathway and inducing epithelial-mesenchymal transition.
ALKBH5-PYCR2 Positive Feedback Loop Promotes Proneural-Mesenchymal Transition Via Proline Synthesis In GBM.
Suppression of Wnt/β-catenin Signaling in PDAC via METTL16-mediated N6-methyladenosine Modification of DVL2.
LncRNA HOTAIR Enhances Epithelial-to-mesenchymal Transition to Promote the Migration and Invasion of Liver Cancer by Regulating NUAK1 via Epigenetic Inhibition miR-145-5p Expression.
High SGO2 predicted poor prognosis and high therapeutic value of lung adenocarcinoma and promoted cell proliferation, migration, invasion, and epithelial-to-mesenchymal transformation.
Myricetin suppresses TGF-β-induced epithelial-to-mesenchymal transition in ovarian cancer.
Ultrasound-assisted intravesical botulinum toxin A delivery attenuates acetic acid-induced bladder hyperactivity in rats.
APOC1 exacerbates renal fibrosis through the activation of the NF-κB signaling pathway in IgAN.
The role of the SGK3/TOPK signaling pathway in the transition from acute kidney injury to chronic kidney disease.
A novel prognostic signatures based on metastasis- and immune-related gene pairs for colorectal cancer.
Exploration of epithelial-mesenchymal transition-related lncRNA signature and drug sensitivity in breast cancer.
Establishment of a porcine bronchial epithelial cell line and its application to study innate immunity in the respiratory epithelium.
Investigating the role of FADS family members in breast cancer based on bioinformatic analysis and experimental validation.
Spider venom-derived peptide JZTX-14 prevents migration and invasion of breast cancer cells via inhibition of sodium channels.
A novel risk model of three SUMOylation genes based on RNA expression for potential prognosis and treatment sensitivity prediction in kidney cancer.
The prognostic value of the GPAT/AGPAT gene family in hepatocellular carcinoma and its role in the tumor immune microenvironment.
NPM1 promotes nasopharyngeal carcinoma metastasis and stemness by recruiting Mdm2 to induce the ubiquitination-mediated degradation of p53.
ZY-444 inhibits the growth and metastasis of prostate cancer by targeting TNFAIP3 through TNF signaling pathway.
Circ_0000231 promotes paclitaxel resistance in ovarian cancer by regulating miR-140/RAP1B.
The deubiquitinating enzyme MINDY2 promotes pancreatic cancer proliferation and metastasis by stabilizing ACTN4 expression and activating the PI3K/AKT/mTOR signaling pathway.
Aquaporin 9 is involved in CRC metastasis through DVL2-dependent Wnt/β-catenin signaling activation.
FTH1 indicates poor prognosis and promotes metastasis in head and neck squamous cell carcinoma.
EXOSC10 is a novel hepatocellular carcinoma prognostic biomarker: a comprehensive bioinformatics analysis and experiment verification.
Effect of stem cell conditional medium-loading adhesive hydrogel on TGF-β1-induced endometrial stromal cell fibrosis.
Endothelial AHR activity prevents lung barrier disruption in viral infection.
VIRMA facilitates intrahepatic cholangiocarcinoma progression through epigenetic augmentation of TMED2 and PARD3B mRNA stabilization.
Exosomal miR-21-5p derived from multiple myeloma cells promote renal epithelial-mesenchymal transition through targeting TGF-β/SMAD7 signalling pathway.
CircRNA PDE3B regulates tumorigenicity via the miR-136-5p/MAP3K2 axis of esophageal squamous cell carcinoma.
MIR663AHG as a competitive endogenous RNA regulating TGF-β-induced epithelial proliferation and epithelial-mesenchymal transition in benign prostate hyperplasia.
Linc-ROR Promotes EMT by Targeting miR-204-5p/SMAD4 in Endometriosis.
Glutaredoxin 2 protects lens epithelial cells from epithelial-mesenchymal transition by suppressing mitochondrial oxidative stress-related upregulation of integrin-linked kinase.
Estrogens drive the endoplasmic reticulum-associated degradation and promote proto-oncogene c-Myc expression in prostate cancer cells by androgen receptor/estrogen receptor signaling.
Pharmacological inhibition of SMYD2 protects against cisplatin-induced renal fibrosis and inflammation.
UBE3A and MCM6 synergistically regulate the proliferation and migration of lung adenocarcinoma cells.
Type 2 innate lymphoid cell-derived amphiregulin regulates type II alveolar epithelial cell transdifferentiation in a mouse model of bronchopulmonary dysplasia.
ACSL4 promotes ferroptosis and M1 macrophage polarization to regulate the tumorigenesis of nasopharyngeal carcinoma.
Maintenance of airway epithelial barrier integrity via the inhibition of AHR/EGFR activation ameliorates chronic obstructive pulmonary disease using effective-component combination.
FTZ polysaccharides ameliorate kidney injury in diabetic mice by regulating gut-kidney axis.
Calycosin inhibits triple-negative breast cancer progression through down-regulation of the novel estrogen receptor-α splice variant ER-α30-mediated PI3K/AKT signaling pathway.
Disulfiram suppresses epithelial-mesenchymal transition (EMT), migration and invasion in cervical cancer through the HSP90A/NDRG1 pathway.
GART Functions as a Novel Methyltransferase in the RUVBL1/β-Catenin Signaling Pathway to Promote Tumor Stemness in Colorectal Cancer.
Macrophage migration inhibitory factor exacerbates asthmatic airway remodeling via dynamin-related protein 1-mediated autophagy activation.
CBX3 promotes clear cell renal carcinoma through PI3K/AKT activation and aberrant immunity.
Pleckstrin-2 promotes tumour immune escape from NK cells by activating the MT1-MMP-MICA signalling axis in gastric cancer.
Long non-coding RNA MIDEAS-AS1 inhibits growth and metastasis of triple-negative breast cancer via transcriptionally activating NCALD.
Intercellular adhesion molecule 2 as a novel prospective tumor suppressor induced by ERG promotes ubiquitination-mediated radixin degradation to inhibit gastric cancer tumorigenicity and metastasis.
E-Cadherin Is Expressed in Epithelial Cells of the Choroid Plexus in Human and Mouse Brains.
Nuciferine Inhibits Oral Squamous Cell Carcinoma Partially through Suppressing the STAT3 Signaling Pathway.
Long intergenic non-coding RNA DIO3OS promotes osteosarcoma metastasis via activation of the TGF-β signaling pathway: a potential diagnostic and immunotherapeutic target for osteosarcoma.
Combination of Kaempferol and Docetaxel Induces Autophagy in Prostate Cancer Cells In Vitro and In Vivo.
SPI1-Mediated Upregulation of the CST1 Gene as an Independent Poor Prognostic Factor Accelerates Metastasis in Esophageal Squamous Cell Carcinoma (ESCC) by Interacting with MMP2.
DSCC1 interacts with HSP90AB1 and promotes the progression of lung adenocarcinoma via regulating ER stress.
Methylation of BRD4 by PRMT1 regulates BRD4 phosphorylation and promotes ovarian cancer invasion.
Characterization and optimization of variability in a human colonic epithelium culture model.
[Aumolertinib inhibits proliferation, invasion and migration and promotes apoptosis of neuroblastoma cells by downregulating MMP2 and MMP9 expression].
Pan-cancer analysis and experimental validation identify ndc1 as a potential immunological, prognostic and therapeutic biomarker in pancreatic cancer.
Progranulin promoted the proliferation, metastasis, and suppressed apoptosis via JAK2-STAT3/4 signaling pathway in papillary thyroid carcinoma.
Hypoxia-inducible factor upregulation by roxadustat attenuates drug reward by altering brain iron homoeostasis.
Modified Gegen Qinlian decoction ameliorated ulcerative colitis by attenuating inflammation and oxidative stress and enhancing intestinal barrier function in vivo and in vitro.
circAGTPBP1 promotes the progression of papillary thyroid cancer through the notch pathway via the miR-34a-5p/notch1 axis.
Nephroprotective Effects of Cardamonin on Renal Ischemia Reperfusion Injury/UUO-Induced Renal Fibrosis.
POFUT1 promotes gastric cancer progression through Notch/Wnt dual signaling pathways dependent on the parafibromin-NICD1-β-catenin complex.
Shikonin suppresses small cell lung cancer growth via inducing ATF3-mediated ferroptosis to promote ROS accumulation.
Distinct invasive patterns in situ between estrogen receptor-positive and triple-negative breast cancer through the intraductal tracking of carbon nanoparticles.
CircUSP10 promotes liver cancer progression by regulating miR-211-5p/TCF12/EMT signaling pathway.
ANKRD22 knockdown suppresses papillary thyroid cell carcinoma growth and migration and modulates the Wnt/β-catenin signaling pathway.
Pingxiao capsule inhibits lung metastasis of triple-negative breast cancer and sensitizes breast cancer to radiotherapy.
Degradation of HIF-1α induced by curcumol blocks glutaminolysis and inhibits epithelial-mesenchymal transition and invasion in colorectal cancer cells.
Regulation of the stem‑like properties of estrogen receptor‑positive breast cancer cells through NR2E3/NR2C2 signaling.
Nrf3 promotes the proliferation and migration of triple‑negative breast cancer by activating PI3K/AKT/mTOR and epithelial‑mesenchymal transition.
ACLY promotes gastric tumorigenesis and accelerates peritoneal metastasis of gastric cancer regulated by HIF-1A.
IGF2BP2 promotes glycolysis and hepatocellular carcinoma stemness by stabilizing CDC45 mRNA via m6A modification.
Knockdown of ABHD11‑AS1 prevents the procession of TNBC by upregulating miR‑199a‑5p.
Lemur tyrosine kinase 2 has a tumor-inhibition function in human glioblastoma by regulating the RUNX3/Notch pathway.
Ampelopsin attenuates Staphylococcus aureus Alpha-Toxin-Induced Lung Injury.
Nintedanib inhibits normal human vitreous-induced epithelial-mesenchymal transition in human retinal pigment epithelial cells.
Discovery of small molecule β-catenin suppressors that enhance immunotherapy.
UBE2V2 promotes metastasis by regulating EMT and predicts a poor prognosis in lung adenocarcinoma.
Role of Nucleobindin-2 in the Clinical Pathogenesis and Treatment Resistance of Glioblastoma.
Placenta mesenchymal stem cell-derived extracellular vesicles alleviate liver fibrosis by inactivating hepatic stellate cells through a miR-378c/SKP2 axis.
Fu-Zheng-Tong-Luo formula promotes autophagy and alleviates idiopathic pulmonary fibrosis by controlling the Janus kinase 2/signal transducer and activator of transcription 3 pathway.
Xue-Jie-San prevents the early development of colitis-associated intestinal fibrosis by blocking Notch1 and FGL1 signaling pathways.
Dynamic interactions between E-cadherin and Ankyrin-G mediate epithelial cell polarity maintenance.
CRTC2 activates the epithelial-mesenchymal transition of diabetic kidney disease through the CREB-Smad2/3 pathway.
Gut Bacterial Community Determines the Therapeutic Effect of Ginsenoside on Canine Inflammatory Bowel Disease by Modulating the Colonic Mucosal Barrier.
Minichromosome maintenance 6 protects against renal fibrogenesis by regulating DUSP6-mediated ERK/GSK-3β/Snail1 signaling.
High glucose promotes benign prostatic hyperplasia by downregulating PDK4 expression.
CYP19A1 promotes gastric cancer as part of a lipid metabolism-related gene signature related to the response of immunotherapy and prognosis.
Eriocitrin inhibits epithelial-mesenchymal transformation (EMT) in lung adenocarcinoma cells via triggering ferroptosis.
USP53 Exerts Tumor-Promoting Effects in Triple-Negative Breast Cancer by Deubiquitinating CRKL.
PM(2.5) induces renal tubular injury by activating NLRP3-mediated pyroptosis.
Dendrobium officinale polysaccharide Converts M2 into M1 Subtype Macrophage Polarization via the STAT6/PPAR-r and JAGGED1/NOTCH1 Signaling Pathways to Inhibit Gastric Cancer.
A pan-cancer analysis of the role of HOXD1, HOXD3, and HOXD4 and validation in renal cell carcinoma.
Fucoidan/chitosan layered PLGA nanoparticles with melatonin loading for inducing intestinal absorption and addressing triple-negative breast cancer progression.
Exploring the anticancer potential of Actinidia chinensis Planch root extracts (acRoots) on hepatocellular carcinoma: A molecular mechanism study.
TRIM16 E121D variant affects the risk and prognosis of hepatocellular carcinoma by modulating the Wnt/β-catenin pathway.
Circ_0001589/miR-1248/HMGB1 axis enhances EMT-mediated metastasis and cisplatin resistance in cervical cancer.
Macrophage microvesicle-derived circ_YTHDF2 in methamphetamine-induced chronic lung injury.
BMP4 Regulates EMT to be Involved in non-Syndromic Cleft lip With or Without Palate.
RNA‑binding protein quaking 5 inhibits the progression of non‑small cell lung cancer by upregulating netrin‑4 expression.
Inhibition of TMEM16A improves cisplatin-induced acute kidney injury via preventing DRP1-mediated mitochondrial fission.
PAR2 deficiency tunes inflammatory microenvironment to magnify STING signalling for mitigating cancer metastasis via anionic CRISPR/Cas9 nanoparticles.
PCSK9 promotes tumor cell proliferation and migration by facilitating CCL25 secretion in esophageal squamous cell carcinoma.
B4GALNT1 promotes carcinogenesis by regulating epithelial-mesenchymal transition in hepatocellular carcinoma based on pan-cancer analysis.
Dauricine regulates prostate cancer progression by inhibiting PI3K/AKT-dependent M2 polarization of macrophages.
Hyperbranched polyamidoamine-RGD peptide/si-circICA1 in the treatment of invasive thyroid cancer through targeting of the miR-486-3p/SERPINA1 axis.
CTRP6 regulates M1 macrophage polarization via the PPAR-γ/NF-κB pathway and reprogramming glycolysis in recurrent spontaneous abortion.
Icaritin inhibits endometrial carcinoma cells by suppressing O-GlcNAcylation of FOXC1.
Schisandrin B Alleviates Renal Tubular Cell Epithelial-Mesenchymal Transition and Mitochondrial Dysfunction by Kielin/Chordin-like Protein Upregulation via Akt Pathway Inactivation and Adenosine 5'-Monophosphate (AMP)-Activated Protein Kinase Pathway Activation in Diabetic Kidney Disease.
NF-κB downstream miR-1262 disturbs colon cancer cell malignant behaviors by targeting FGFR1.
LMP2 and TAP2 impair tumor growth and metastasis by inhibiting Wnt/β-catenin signaling pathway and EMT in cervical cancer.
FAM171B stabilizes vimentin and enhances CCL2-mediated TAM infiltration to promote bladder cancer progression.
Decreased fucosylation impacts epithelial integrity and increases risk for COPD.
MircroRNA-92b as a negative regulator of the TGF-β signaling by targeting the type I receptor.
Curcumin Disrupts a Positive Feedback Loop between ADMSCs and Cancer Cells in the Breast Tumor Microenvironment via the CXCL12/CXCR4 Axis.
LASS2 enhances p53 protein stability and nuclear import to suppress liver cancer progression through interaction with MDM2/MDMX.
IGFBP2 drives epithelial-mesenchymal transition in hepatocellular carcinoma via activating the Wnt/β-catenin pathway.
GAD1-mediated GABA elicits aggressive characteristics of human oral cancer cells.
Lnc AC016727.1/BACH1/HIF-1 α signal loop promotes the progression of non-small cell lung cancer.
The HDAC inhibitor HFY-4A improves TUSC2 transcription to induce immunogenic cell death in breast cancer.
Piezoeletric cold atmospheric plasma induces apoptosis and autophagy in human hepatocellular carcinoma cells through blocking glycolysis and AKT/mTOR/HIF-1α pathway.
Suprabasin enhances the invasion, migration, and angiogenic ability of oral squamous cell carcinoma cells under hypoxic conditions.
Alpha lipoamide inhibits diabetic kidney fibrosis via improving mitochondrial function and regulating RXRα expression and activation.
CircRNA_0017076 acts as a sponge for miR-185-5p in the control of epithelial-to-mesenchymal transition of tubular epithelial cells during renal interstitial fibrosis.
Retinoic acid-loaded PLGA nanocarriers targeting cell cholesterol potentialize the antitumour effect of PD-L1 antibody by preventing epithelial-mesenchymal transition mediated by M2-TAM in colorectal cancer.
ADAM12 promotes gemcitabine resistance by activating EGFR signaling pathway and induces EMT in bladder cancer.
CircRNA OXCT1 promotes the malignant progression and glutamine metabolism of non-small cell lung cancer by absorbing miR-516b-5p and upregulating SLC1A5.
Nicotine exposure exacerbates silica-induced pulmonary fibrosis via STAT3-BDNF-TrkB-mediated epithelial-mesenchymal transition in alveolar type II cells.
Nintedanib prevents TGF-β2-induced epithelial-mesenchymal transition in retinal pigment epithelial cells.
Extracellular vesicles derived from Akkermansia muciniphila promote placentation and mitigate preeclampsia in a mouse model.
BZW1 as an oncogene is associated with patient prognosis and the immune microenvironment in glioma.
The NR_109/FUBP1/c-Myc axis regulates TAM polarization and remodels the tumor microenvironment to promote cancer development.
MicroRNA-150-5p inhibits the proliferation and invasion of human larynx epidermiod cancer cells though regulating peptidyl-prolyl cis/trans isomerase.
miR-137-LAPTM4B regulates cytoskeleton organization and cancer metastasis via the RhoA-LIMK-Cofilin pathway in osteosarcoma.
Effects of Therapeutic Platelet-Rich Plasma on Overactive Bladder via Modulating Hyaluronan Synthesis in Ovariectomized Rat.
Suppression of TGFβR-Smad3 pathway alleviates the syrinx induced by syringomyelia.
High Level of GMFG Correlated to Poor Clinical Outcome and Promoted Cell Migration and Invasion through EMT Pathway in Triple-Negative Breast Cancer.
Rhein Inhibited Ferroptosis and EMT to Attenuate Diabetic Nephropathy by Regulating the Rac1/NOX1/β-Catenin Axis.
The mediation of the AHR/IL-22/STAT3/IL-6 axis by soft-shelled turtle (Pelodiscus sinensis) peptide and Chinese pond turtle (Chinemys reevesii) peptide contributed to their amelioration effects on intestinal mucosal immunity in immunosuppressed mice.
CEBPG suppresses ferroptosis through transcriptional control of SLC7A11 in ovarian cancer.
Alterations in histology of the aging salivary gland and correlation with the glandular inflammatory microenvironment.
USP22 aggravated diabetic renal tubulointerstitial fibrosis progression through deubiquitinating and stabilizing Snail1.
Guanine nucleotide exchange factor T exerts the cancer-promoting function in cholangiocarcinoma by enhancing the Wnt-GSK-3β-β-catenin cascade via regulation of Rac1/Cdc42.
PRMT2 promotes RCC tumorigenesis and metastasis via enhancing WNT5A transcriptional expression.
Yishen Tongluo formula alleviates diabetic kidney disease through regulating Sirt6/TGF-β1/Smad2/3 pathway and promoting degradation of TGF-β1.
Growth and Migration Blocking Effect of Nanaomycin K, a Compound Produced by Streptomyces sp., on Prostate Cancer Cell Lines In Vitro and In Vivo.
Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy.
Decreasing expression of Prohibitin-2 lowers the oncogenicity of renal cell carcinoma cells by suppressing eIF4E-mediated oncogene translation via MNK inhibition.
KIFC3 regulates progression of hepatocellular carcinoma via EMT and the AKT/mTOR pathway.
Salt-like transcription factor 4 promotes laryngeal cancer progression through transcriptional activation of ubiquitin-specific protease 21 to stabilize Yin Yang 1.
Thiol oxidative stress-dependent degradation of transglutaminase2 via protein S-glutathionylation sensitizes 5-fluorouracil therapy in 5-fluorouracil-resistant colorectal cancer cells.
MiR-29a-3p inhibits high-grade transformation and epithelial-mesenchymal transition of lacrimal gland adenoid cystic carcinoma by targeting Quaking.
Exosomes from tubular epithelial cells undergoing epithelial-to-mesenchymal transition promote renal fibrosis by M1 macrophage activation.
miR‑151a‑5p promotes the proliferation and metastasis of colorectal carcinoma cells by targeting AGMAT.
The role of interleukin 36γ in the epithelial-mesenchymal transition process of chronic rhinosinusitis: A pilot study.
Circ_0056618 enhances PRRG4 expression by competitively binding to miR-411-5p to promote the malignant progression of colorectal cancer.
RASSF1A inhibits epithelial-mesenchymal transition of gastric cancer cells by downregulating P-JNK.
CircNFIX stimulates the proliferation, invasion, and stemness properties of ovarian cancer cells by enhancing SH3RF3 mRNA stability via binding LIN28B.
Silencing RPL8 inhibits the progression of hepatocellular carcinoma by down-regulating the mTORC1 signalling pathway.
Immunity-related long noncoding RNA WDFY3-AS2 inhibited cell proliferation and metastasis through Wnt/β-catenin signaling in oral squamous cell carcinoma.
Cyclin-dependent kinase subunit2 (CKS2) promotes malignant phenotypes and epithelial-mesenchymal transition-like process in glioma by activating TGFβ/SMAD signaling.
Aspartame consumption during pregnancy impairs placenta growth in mice through sweet taste receptor-reactive oxygen species-dependent pathway.
1,25(OH)(2) D(3) induced vitamin D receptor signaling negatively regulates endoplasmic reticulum-associated degradation (ERAD) and androgen receptor signaling in human prostate cancer cells.
NETs Promote Inflammatory Injury by Activating cGAS-STING Pathway in Acute Lung Injury.
The Enzyme 15-Hydroxyprostaglandin Dehydrogenase Inhibits a Shift to the Mesenchymal Pattern of Trophoblasts and Decidual Stromal Cells Accompanied by Prostaglandin Transporter in Preeclampsia.
HSPA5 Promotes the Proliferation, Metastasis and Regulates Ferroptosis of Bladder Cancer.
SEMA6C: a novel adhesion-independent FAK and YAP activator, required for cancer cell viability and growth.
CPT1A modulates PI3K/Akt/mTOR pathway to promote preeclampsia.
Demethylase FTO enhances the PI3K/Akt signaling to promote gastric cancer malignancy.
Fatostatin induces ferroptosis through inhibition of the AKT/mTORC1/GPX4 signaling pathway in glioblastoma.
NONHSAT021545/miR-330-3p/EREG: A Cooperative Axis in Breast Cancer Prognosis and Treatment.
Discovery of Potent DYRK2 Inhibitors with High Selectivity, Great Solubility, and Excellent Safety Properties for the Treatment of Prostate Cancer.
Receptor tyrosine kinase C-kit promotes a destructive phenotype of FLS in osteoarthritis via intracellular EMT signaling.
SEPT2 crotonylation promotes metastasis and recurrence in hepatocellular carcinoma and is associated with poor survival.
CCR7 Mediates Cell Invasion and Migration in Extrahepatic Cholangiocarcinoma by Inducing Epithelial-Mesenchymal Transition.
LncRNA-MIAT activates hepatic stellate cells via regulating Hippo pathway and epithelial-to-mesenchymal transition.
EGR1 induces EMT in pancreatic cancer via a P300/SNAI2 pathway.
PRAME Promotes Cervical Cancer Proliferation and Migration via Wnt/β-Catenin Pathway Regulation.
F-box and leucine-rich repeat 6 promotes gastric cancer progression via the promotion of epithelial-mesenchymal transition.
Ultrasound-mediated mesoporous silica nanoparticles loaded with PDLIM5 siRNA inhibit gefitinib resistance in NSCLC cells by attenuating EMT.
TMEM2 induces epithelial-mesenchymal transition and promotes resistance to temozolomide in GBM cells.
Potent carotenoid astaxanthin expands the anti-cancer activity of cisplatin in human prostate cancer cells.
PDK1 regulates the progression of esophageal squamous cell carcinoma through metabolic reprogramming.
Rabeprazole destroyed gastric epithelial barrier function through FOXF1/STAT3-mediated ZO-1 expression.
FAM83A promotes the progression and metastasis of human pancreatic neuroendocrine tumors by inducing the epithelial-mesenchymal transition via the PI3K/AKT and ERK pathways.
ZNF133 is a potent suppressor in breast carcinogenesis through dampening L1CAM, a driver for tumor progression.
Circ_0079530 stimulates THBS2 to promote the malignant progression of non-small cell lung cancer by sponging miR-584-5p.
Meso-Hannokinol inhibits breast cancer bone metastasis via the ROS/JNK/ZEB1 axis.
Loss of exosomal miR-200b-3p from hypoxia cancer-associated fibroblasts promotes tumorigenesis and reduces sensitivity to 5-Flourouracil in colorectal cancer via upregulation of ZEB1 and E2F3.
HnRNPAB is an independent prognostic factor in non‑small cell lung cancer and is involved in cell proliferation and metastasis.
Silencing of FAM111B inhibits tumor growth and promotes apoptosis by decreasing AKT activity in ovarian cancer.
Intracellular hydrogelation of macrophage conjugated probiotics for hitchhiking delivery and combined treatment of colitis.
Rosmarinic Acid-Crosslinked Supramolecular Nanoassembly with Self-Regulated Photodynamic and Anti-Metastasis Properties for Synergistic Photoimmunotherapy.
LINC01116 modulates EMT process via binding with AGO1 mRNA in oesophageal squamous cell carcinoma.
Squalene epoxidase promotes hepatocellular carcinoma development by activating STRAP transcription and TGF-β/SMAD signalling.
TRIM55 inhibits colorectal cancer development via enhancing protein degradation of c-Myc.
Cancer cell-derived CD69 induced under lipid and oxygen starvation promotes ovarian cancer progression through fibronectin.
MED27 plays a tumor-promoting role in breast cancer progression by targeting KLF4.
Effect of STK3 on proliferation and apoptosis of pancreatic cancer cells via PI3K/AKT/mTOR pathway.
Clinicopathological features and immunophenotype of Silva pattern system in endocervical adenocarcinoma.
MTAP-ANRIL gene fusion promotes melanoma epithelial-mesenchymal transition-like process by activating the JNK and p38 signaling pathways.
Silencing of AJAP1 expression by promoter methylation activates the Wnt/β-catenin signaling pathway to promote tumor proliferation and metastasis in salivary adenoid cystic carcinoma.
Morusin shows potent antitumor activity for melanoma through apoptosis induction and proliferation inhibition.
GATA zinc finger protein p66β promotes breast cancer cell migration by acting as a co-activator of Snail.
High glucose promotes the progression of colorectal cancer by activating the BMP4 signaling and inhibited by glucagon-like peptide-1 receptor agonist.
TRIM29 hypermethylation drives esophageal cancer progression via suppression of ZNF750.
PLAGL2 promotes Snail expression and gastric cancer progression via UCA1/miR-145-5p/YTHDF1 axis.
SIAH1/CTR9 axis promotes the epithelial-mesenchymal transition of hepatocellular carcinoma.
FBXO28 promotes proliferation, invasion, and metastasis of pancreatic cancer cells through regulation of SMARCC2 ubiquitination.
UBAP2 plays a role in bone homeostasis through the regulation of osteoblastogenesis and osteoclastogenesis.
Regulon analysis identifies protective FXR and CREB5 in proximal tubules in early diabetic kidney disease.
An In Vivo CRISPR Screen Identifies That SNRPC Promotes Triple-Negative Breast Cancer Progression.
ORP8 inhibits renal cell carcinoma progression by accelerating Stathmin1 degradation and microtubule polymerization.
Targeting the mitochondrial calcium uniporter inhibits cancer progression and alleviates cisplatin resistance in esophageal squamous cell carcinoma.
ASPM promotes migration and invasion of anaplastic thyroid carcinoma by stabilizing KIF11.
ORP5 promotes migration and invasion of cervical cancer cells by inhibiting endoplasmic reticulum stress.
MRPL51 is a downstream target of FOXM1 in promoting the malignant behaviors of lung adenocarcinoma.
Analysis and validation of the potential of the MYO1E gene in pancreatic adenocarcinoma based on a bioinformatics approach.
Dach1 deficiency drives alveolar epithelium apoptosis in pulmonary fibrosis via modulating C-Jun/Bim activity.
TANGO1 interacts with NRTN to promote hepatocellular carcinoma progression by regulating the PI3K/AKT/mTOR signaling pathway.
SIRT3-mediated autophagy contributes to ferroptosis-induced anticancer by inducing the formation of BECN1-SLC7A11 complex.
The role of DYNLT3 in breast cancer proliferation, migration, and invasion via epithelial-to-mesenchymal transition.
Pan-cancer analysis of oncogenic role of insulin-like growth factor-binding proteins and validation in ovarian cancer.
HERPUD1, a Member of the Endoplasmic Reticulum Protein Quality Control Mechanism, may be a Good Target for Suppressing Tumorigenesis in Breast Cancer Cells.
LncRNA LZTS1-AS1 induces proliferation, metastasis and inhibits autophagy of pancreatic cancer cells through the miR-532 /TWIST1 signaling pathway.
The promoting effect and mechanism of Nrf2 on cell metastasis in cervical cancer.
Modified Podophyllotoxin Phenoxyacetamide Phenylacetate Derivatives: Tubulin/AKT1 Dual-Targeting and Potential Anticancer Agents for Human NSCLC.
Lnc-LRRTM4 promotes proliferation, metastasis and EMT of colorectal cancer through activating LRRTM4 transcription.
NCOA7 Regulates Growth and Metastasis of Clear Cell Renal Cell Carcinoma via MAPK/ERK Signaling Pathway.
PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling.
Long noncoding RNA LINC01594 inhibits the CELF6-mediated splicing of oncogenic CD44 variants to promote colorectal cancer metastasis.
AFP deletion leads to anti-tumorigenic but pro-metastatic roles in liver cancers with concomitant CTNNB1 mutations.
Knockdown of ABCB7 inhibits esophageal cancer progression by inhibiting the TGF-β/Smad signaling.
TATA-box-binding protein promotes hepatocellular carcinoma metastasis through epithelial-mesenchymal transition.
Extracellular Vesicles from Carcinoma-associated Fibroblasts Promote EMT of Salivary Adenoid Cystic Carcinoma Via IL-6.
Biochemical and clinical effects of RPS20 expression in renal clear cell carcinoma.
SPARC expression in tumor microenvironment induces partial epithelial-to-mesenchymal transition of esophageal adenocarcinoma cells via cooperating with TGF-β signaling.
Exosome-transmitted circIFNGR2 Modulates Ovarian Cancer Metastasis via miR-378/ST5 Axis.
Resveratrol reverses TGF-β1-mediated invasion and metastasis of breast cancer cells via the SIRT3/AMPK/autophagy signal axis.
Quercetin inhibits the amphiregulin/EGFR signaling-mediated renal tubular epithelial-mesenchymal transition and renal fibrosis in obstructive nephropathy.
Effect of transmembrane protein 100 on prostate cancer progression by regulating SCNN1D through the FAK/PI3K/AKT pathway.
CD166-specific CAR-T cells potently target colorectal cancer cells.
Circ_0004491 stimulates guanine nucleotide-binding protein alpha subunit to inhibit the malignant progression of oral squamous cell carcinoma by sponging miR-2278.
Exosomal miR-543 derived from umbilical cord mesenchymal stem cells ameliorates endometrial fibrosis in intrauterine adhesion via downregulating N-cadherin.
CDCA7 promotes TGF-β-induced epithelial-mesenchymal transition via transcriptionally regulating Smad4/Smad7 in ESCC.
Multiomics analyses and machine learning of nuclear receptor coactivator 6 reveal its essential role in hepatocellular carcinoma.
Mouse-human species differences in early testicular development and its implications.
Cancer susceptibility 18 positively regulates NUAK Family Kinase 1 expression to promote migration and invasion via sponging of miR-5586-5p in cervical cancer cells.
Hypermethylation-Mediated lncRNA MAGI2-AS3 Downregulation Facilitates Malignant Progression of Laryngeal Squamous Cell Carcinoma via Interacting With SPT6.
GOLM1 Promotes Epithelial-Mesenchymal Transition by Activating TGFβ1/Smad2 Signaling in Prostate Cancer.
Cryptotanshinone modulates proliferation, apoptosis, and fibrosis through inhibiting AR and EGFR/STAT3 axis to ameliorate benign prostatic hyperplasia progression.
Circular hsa_circ_0020377 regulates KLF7 by targeting miR-194-5p to facilitate tumor cell malignant behaviors and glycolysis in oral squamous cell carcinoma progression.
Alginate Oligosaccharides Prevent Dextran-Sulfate-Sodium-Induced Ulcerative Colitis via Enhancing Intestinal Barrier Function and Modulating Gut Microbiota.
Glycolysis-Related Gene Analyses Indicate That DEPDC1 Promotes the Malignant Progression of Oral Squamous Cell Carcinoma via the WNT/β-Catenin Signaling Pathway.
CCL21/CCR7 Axis Contributes to Trophoblastic Cell Migration and Invasion in Preeclampsia by Affecting the Epithelial Mesenchymal Transition via the ERK1/2 Signaling Pathway.
Hypoxia-induced ROS aggravate tumor progression through HIF-1α-SERPINE1 signaling in glioblastoma.
Molecular mechanism of the miR-7/BCL2L1/P53 signaling axis regulating the progression of hepatocellular carcinoma.
SF3B4 promotes Twist1 expression and clear cell renal cell carcinoma progression by facilitating the export of KLF 16 mRNA from the nucleus to the cytoplasm.
FRMD3 inhibits the growth and metastasis of breast cancer through the ubiquitination-mediated degradation of vimentin and subsequent impairment of focal adhesion.
CMTM6 overexpression confers trastuzumab resistance in HER2-positive breast cancer.
Crosstalk between 5-methylcytosine and N(6)-methyladenosine machinery defines disease progression, therapeutic response and pharmacogenomic landscape in hepatocellular carcinoma.
High expression of NLRP12 predicts poor prognosis in patients with intracranial glioma.
Etomidate elicits anti-tumor capacity by disrupting the JAK2/STAT3 signaling pathway in hepatocellular carcinoma.
GOLM1 facilitates human colorectal cancer progression and metastasis via activating the AKT/GSK3β/EMT axis.
The TGF-β/Smad(2/3) signaling pathway is involved in Musashi2-induced invasion and metastasis of colorectal cancer.
Silencing CircEIF3I/miR-526b-5p Axis Epigenetically Targets HGF/c-Met Signal to Hinder the Malignant Growth, Metastasis and Angiogenesis of Hepatocellular Carcinoma.
The long non-coding RNA PANDAR regulates cell proliferation and epithelial-to-mesenchymal transition in glioma.
Novel long noncoding RNA LINC02820 augments TNF signaling pathway to remodel cytoskeleton and potentiate metastasis in esophageal squamous cell carcinoma.
Role of SUMOylation of STAT1 in tubular epithelial‑mesenchymal transition induced by high glucose.
Palladin promotes cancer stem cell-like properties in lung cancer by activating Wnt/Β-Catenin signaling.
Hepatic stellate cell-released CXCL1 aggravates HCC malignant behaviors through the MIR4435-2HG/miR-506-3p/TGFB1 axis.
Ferroptosis is involved in corpus cavernosum smooth muscle cells impairment in diabetes mellitus-induced erectile dysfunction.
LIM and Cysteine-Rich Domains 1 Promotes Transforming Growth Factor β1-Induced Epithelial-Mesenchymal Transition in Human Kidney 2 Cells.
TRIM40 is a pathogenic driver of inflammatory bowel disease subverting intestinal barrier integrity.
Ginsenoside Rg3 Ameliorates DSS-Induced Colitis by Inhibiting NLRP3 Inflammasome Activation and Regulating Microbial Homeostasis.
RRP15 deficiency induces ribosome stress to inhibit colorectal cancer proliferation and metastasis via LZTS2-mediated β-catenin suppression.
Proto-Oncogene FAM50A Can Regulate the Immune Microenvironment and Development of Hepatocellular Carcinoma In Vitro and In Vivo.
The UDPase ENTPD5 regulates ER stress-associated renal injury by mediating protein N-glycosylation.
Serum Response Factor-Regulated IDO1/Kyn-Ahr Pathway Promotes Tumorigenesis of Oral Squamous Cell Carcinoma.
Aerobic exercise inhibits renal EMT by promoting irisin expression in SHR.
The malignancy of chordomas is enhanced via a circTLK1/miR-16-5p/Smad3 positive feedback axis.
ELAC2 Functions as a Key Gene in the Early Development of Placental Formation Based on WGCNA.
METTL3 depletion contributes to tumour progression and drug resistance via N6 methyladenosine-dependent mechanism in HR+HER2-breast cancer.
UBE2E2 enhances Snail-mediated epithelial-mesenchymal transition and Nrf2-mediated antioxidant activity in ovarian cancer.
CircPTK2/PABPC1/SETDB1 axis promotes EMT-mediated tumor metastasis and gemcitabine resistance in bladder cancer.
Exosomes derived from human umbilical cord mesenchymal stem cells loaded with RVG-Lamp2b and Netrin-1 promotes Schwann cell invasion and migration.
AKAP12 inhibits esophageal squamous carcinoma cell proliferation, migration, and cell cycle via the PI3K/AKT signaling pathway.
Loke zupa decoction attenuates bronchial EMT-mediated airway remodelling in chronic asthma through the PI3K-Akt/HIF-1α signaling pathway.
Mechanisms of dihydromyricetin against hepatocellular carcinoma elucidated by network pharmacology combined with experimental validation.
Transcriptome sequencing identifies prognostic genes involved in gastric adenocarcinoma.
Selumetinib overcomes gefitinib primary and acquired resistance by regulating MIG6/STAT3 in NSCLC.
Brusatol enhances MEF2A expression to inhibit RCC progression through the Wnt signalling pathway in renal cell carcinoma.
hsa-miR-1301-3p Promotes the Proliferation and Migration of Nonsmall Cell Lung Cancer Cells and Reduces Radiosensitivity via Targeting Homeodomain-Only Protein Homeobox.
Isoliquiritigenin suppresses the progression of malignant melanoma via targeting H2A.Z.1-E2F1 pathway.
Trigonelline inhibits tubular epithelial-mesenchymal transformation in diabetic kidney disease via targeting Smad7.
Cell-in-Cell-Mediated Entosis Reveals a Progressive Mechanism in Pancreatic Cancer.
Hydroxypropyl-β-cyclodextrin inhibits the development of triple negative breast cancer by enhancing antitumor immunity.
Multi-omics analysis reveals the mechanism of action of ophiopogonin D against pulmonary fibrosis.
CircRNA0007766 accelerates cancer progression via miR-34c-5p/cyclin D1 axis in adenocarcinoma of the esophagogastric junction (AEG).
LncRNA MIR200CHG inhibits EMT in gastric cancer by stabilizing miR-200c from target-directed miRNA degradation.
ACTN1 promotes HNSCC tumorigenesis and cisplatin resistance by enhancing MYH9-dependent degradation of GSK-3β and integrin β1-mediated phosphorylation of FAK.
RUNX1 knockdown induced apoptosis and impaired EMT in high-grade serous ovarian cancer cells.
PRRSV alters m(6)A methylation and alternative splicing to regulate immune, extracellular matrix-associated function.
Sinapine thiocyanate exhibited anti-colorectal cancer effects by inhibiting KRT6A/S100A2 axis.
VAMP8 suppresses the metastasis via DDX5/β-catenin signal pathway in osteosarcoma.
Lnc-PKNOX1-1 inhibits tumor progression in cutaneous malignant melanoma by regulating NF-κB/IL-8 axis.
Cell-cell and cell-matrix adhesion regulated by Piezo1 is critical for stiffness-dependent DRG neuron aggregation.
DPP4 Regulates the Th17/IL-17 Axis and Accelerates Epithelial Mesenchymal Transition to Promote Ovalbumin-Induced Asthma in Female C57BL/6J Mice.
The nucleolar protein NIFK accelerates the progression of colorectal cancer via activating MYC pathway.
Histone demethylase KDM4B accelerates the progression of glioblastoma via the epigenetic regulation of MYC stability.
Inhibition of PFKP in renal tubular epithelial cell restrains TGF-β induced glycolysis and renal fibrosis.
Therapeutic protein PAK restrains the progression of triple negative breast cancer through degrading SREBP-1 mRNA.
Dissecting T-cell heterogeneity in esophageal squamous cell carcinoma reveals the potential role of LAIR2 in antitumor immunity.
Squalene epoxidase promotes breast cancer progression by regulating CCNB1 protein stability.
Ginsenoside Rg1 Alleviates Lipopolysaccharide-Induced Fibrosis of Endometrial Epithelial Cells in Dairy Cows by Inhibiting Reactive Oxygen Species-Activated NLRP3.
TAGLN2 Promotes the Proliferation, Migration, Invasion, and EMT of Clear Cell Renal Cell Carcinoma Through the PI3K/Akt Signaling Pathway.
Aquaporin 1 is a prognostic marker and inhibits tumour progression through downregulation of Snail expression in intrahepatic cholangiocarcinoma.
KIF15 knockdown inhibits the development of endometrial cancer by suppressing epithelial-mesenchymal transition and stemness through Wnt/β-catenin signaling.
Withdrawal: CircKIAA1429 accelerates hepatocellular carcinoma advancement by miR-199b-5p/OTX1 pathway, by Bin Lu, Min Cheng, Tao Wang.
Journal of viral hepatitis 2023 Aug;30(8):713
ISL1 regulates lung branching morphogenesis via Shh signaling pathway.
Profilin1 Regulates Trophoblast Invasion and Macrophage Differentiation.
MALAT1 binds to miR-188-3p to regulate ALOX5 activity in the lung inflammatory response of neonatal bronchopulmonary dysplasia.
Long non-coding RNA ENST00000503625 is a potential prognostic biomarker and metastasis suppressor gene in prostate cancer.
PRSS2 regulates EMT and metastasis via MMP-9 in gastric cancer.
Inhibition of IL-4/STAT6/IRF4 signaling reduces the epithelial-mesenchymal transition in eosinophilic chronic rhinosinusitis with nasal polyps.
The ALOX5 inhibitor Zileuton regulates tumor-associated macrophage M2 polarization by JAK/STAT and inhibits pancreatic cancer invasion and metastasis.
ROS Scavenging Nanozyme Modulates Immunosuppression for Sensitized Cancer Immunotherapy.
ZDHHC11B is decreased in lung adenocarcinoma and inhibits tumorigenesis via regulating epithelial-mesenchymal transition.
Glutamine and amino acid metabolism as a prognostic signature and therapeutic target in endometrial cancer.
Hypoxic tumor-derived exosomal miR-21 induces cancer-associated fibroblast activation to promote head and neck squamous cell carcinoma metastasis.
NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β/Smad signaling pathways in diabetic nephropathy.
Cancer-associated fibroblasts in the invasive tumour front promote the metastasis of oral squamous cell carcinoma through MFAP5 upregulation.
SMC1A facilitates gastric cancer cell proliferation, migration, and invasion via promoting SNAIL activated EMT.
High Thioredoxin Domain-Containing Protein 11 Expression Is Associated with Tumour Progression in Glioma.
Mutations in CCNB3 affect its location thus causing a multiplicity of phenotypes in human oocytes maturation by aberrant CDK1 activity and APC/C activity at different stages.
Acetyl-cinobufagin suppresses triple-negative breast cancer progression by inhibiting the STAT3 pathway.
Orosomucoid 1 promotes colorectal cancer progression and liver metastasis by affecting PI3K/AKT pathway and inducing macrophage M2 polarization.
MiR-297 inhibits tumour progression of liver cancer by targeting PTBP3.
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway.
UCP1 alleviates renal interstitial fibrosis progression through oxidative stress pathway mediated by SIRT3 protein stability.
Purple Yam Polyphenol Extracts Exert Anticolitis and Anticolitis-Associated Colorectal Cancer Effects through Inactivation of NF-κB/p65 and STAT3 Signaling Pathways.
Transforms of Cell Surface Glycoproteins Charge Influences Tumor Cell Metastasis via Atypically Inhibiting Epithelial-Mesenchymal Transition Including Matrix Metalloproteinases and Cell Junctions.
ADAMDEC1 induces EMT and promotes colorectal cancer cells metastasis by enhancing Wnt/β-catenin signaling via negative modulation of GSK-3β.
Claudin-3 facilitates the progression and mediates the tumorigenic effects of TGF-β in glioblastoma multiforme.
Ubiquitin-specific protease 7 prevents recurrent spontaneous abortion by targeting enhancer of zeste homolog 2 to regulate trophoblast proliferation, apoptosis, migration, and invasion through the Wnt/β-catenin pathway†.
Comprehensive bioinformatics and experimental analysis of SH3PXD2B reveals its carcinogenic effect in gastric carcinoma.
Circular RNA Sec61 subunit alpha isoform 1 by competitive absorption of microRNA-513a-5p mediates peroxisomal biogenesis factor 5 expression and promotes the malignant phenotype of non-small cell lung cancer.
ADAMTS12 promotes migration and epithelial-mesenchymal transition and predicts poor prognosis for pancreatic cancer.
XPO1 intensifies sorafenib resistance by stabilizing acetylation of NPM1 and enhancing epithelial-mesenchymal transition in hepatocellular carcinoma.
Budding uninhibited by benzimidazoles 1 overexpression is associated with poor prognosis and malignant phenotype: A promising therapeutic target for lung adenocarcinoma.
ETV4 Mediated Tumor-Associated Neutrophil Infiltration Facilitates Lymphangiogenesis and Lymphatic Metastasis of Bladder Cancer.
Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.
A potential link between fibroblast growth factor-23 and the progression of AKI to CKD.
Dissecting Rubella Placental Infection in an In Vitro Trophoblast Model.
Targeting BRD3 eradicates nuclear TYRO3-induced colorectal cancer metastasis.
EPC-exosomal miR-26a-5p improves airway remodeling in COPD by inhibiting ferroptosis of bronchial epithelial cells via PTGS2/PGE2 signaling pathway.
LINC00365 functions as a tumor suppressor by inhibiting HIF-1α-mediated glucose metabolism reprogramming in breast cancer.
Aristolochic acid I promotes the invasion and migration of hepatocellular carcinoma cells by activating the C3a/C3aR complement system.
CMTM6 as a candidate risk gene for cervical cancer: Comprehensive bioinformatics study.
Lactobacillus fermentum CECT5716 Alleviates the Inflammatory Response in Asthma by Regulating TLR2/TLR4 Expression.
TRIM47 promotes ovarian cancer cell proliferation, migration, and invasion by activating STAT3 signaling.
Ginsenoside Rd inhibits migration and invasion of tongue cancer cells through H19/miR-675-5p/CDH1 axis.
Non-canonical Small GTPase RBJ Promotes NSCLC Progression Through the Canonical MEK/ERK Signaling Pathway.
IL-33 Participates in the Development of Esophageal Adenocarcinoma.
Carbon Monoxide-Releasing Molecule-3 Suppresses the Malignant Biological Behavior of Tongue Squamous Cell Carcinoma via Regulating Keap1/Nrf2/HO-1 Signaling Pathway.
PHGDH Inhibitor CBR-5884 Inhibits Epithelial Ovarian Cancer Progression via ROS/Wnt/β-Catenin Pathway and Plays a Synergistic Role with PARP Inhibitor Olaparib.
IMP4 Silencing Inhibits the Malignancy of Lung Adenocarcinoma via ERK Pathway.
Keratin 8 Is an Inflammation-Induced and Prognosis-Related Marker for Pancreatic Adenocarcinoma.
JPHYD Inhibits miR-21-5p/Smad7-Mediated Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma Cells.
Xiaotan Sanjie Decoction Inhibits Gastric Cancer Cell Proliferation, Migration, and Invasion through lncRNA-ATB and miR-200A.
Pygo1 Regulates the Behavior of Human Non-Small-Cell Lung Cancer via the Wnt/β-Catenin Pathway.
Comprehensive Pan-Cancer Analysis of IRAK Family Genes Identifies IRAK1 as a Novel Oncogene in Low-Grade Glioma.
Multifunctional Drug-Loaded Phase-Change Nanoparticles Inhibit the Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma by Affecting the Activity of Activated Hepatic Stellate Cells.
The Gut Microbiota Dysbiosis in Preeclampsia Contributed to Trophoblast Cell Proliferation, Invasion, and Migration via lncRNA BC030099/NF-κB Pathway.
Blocking REDD1/TXNIP Complex Ameliorates HG-Induced Renal Tubular Epithelial Cell Apoptosis and EMT through Repressing Oxidative Stress.
TNFAIP6 Promotes Gastric Carcinoma Cell Invasion via Upregulating PTX3 and Activating the Wnt/β-Catenin Signaling Pathway.
ASPM Promotes the Progression of Anaplastic Thyroid Carcinomas by Regulating the Wnt/β-Catenin Signaling Pathway.
CYP26A1 Is a Novel Cancer Biomarker of Pancreatic Carcinoma: Evidence from Integration Analysis and In Vitro Experiments.
HO-1 Contributes to Luteolin-Triggered Ferroptosis in Clear Cell Renal Cell Carcinoma via Increasing the Labile Iron Pool and Promoting Lipid Peroxidation.
Panax Notoginseng Saponins Regulate Transforming Growth Factor-β1 through MAPK and Snail/TWIST1 Signaling Pathway to Inhibit Epithelial-Mesenchymal Transition of Pulmonary Fibrosis in A549 Cells.
Prognostic Lnc-S100B-2 Affects Cell Apoptosis and Microenvironment of Colorectal Cancer through MLLT10 Signaling.
Biochanin A Suppresses Tumor Progression and PD-L1 Expression via Inhibiting ZEB1 Expression in Colorectal Cancer.
Fluorofenidone Inhibits UUO/IRI-Induced Renal Fibrosis by Reducing Mitochondrial Damage.
Upregulated LINC00922 Promotes Epithelial-Mesenchymal Transition and Indicates a Dismal Prognosis in Gastric Cancer.
Novel lncRNA AL033381.2 Promotes Hepatocellular Carcinoma Progression by Upregulating PRKRA Expression.
ROS Promote Hypoxia-Induced Keratinocyte Epithelial-Mesenchymal Transition by Inducing SOX2 Expression and Subsequent Activation of Wnt/β-Catenin.
Upregulation of SQLE Contributes to Poor Survival in Head and Neck Squamous Cell Carcinoma.
UBE2S as a novel ubiquitinated regulator of p16 and β-catenin to promote bone metastasis of prostate cancer.
USP1 inhibition suppresses the progression of osteosarcoma via destabilizing TAZ.
USF1-ATRAP-PBX3 Axis Promote Breast Cancer Glycolysis and Malignant Phenotype by Activating AKT/mTOR Signaling.
Poly (ADP-ribose) polymerase 1 (PARP1) inhibition promotes pulmonary metastasis of osteosarcoma by boosting ezrin phosphorylation.
TBL1X and Flot2 form a positive feedback loop to promote metastasis in nasopharyngeal carcinoma.
Decrease of circARID1A retards glioblastoma invasion by modulating miR-370-3p/ TGFBR2 pathway.
Human CPTP promotes growth and metastasis via sphingolipid metabolite ceramide and PI4KA/AKT signaling in pancreatic cancer cells.
Interaction between BEND5 and RBPJ suppresses breast cancer growth and metastasis via inhibiting Notch signaling.
RNA-binding motif protein 10 represses tumor progression through the Wnt/β- catenin pathway in lung adenocarcinoma.
NR4A1 inhibits the epithelial-mesenchymal transition of hepatic stellate cells: Involvement of TGF-β-Smad2/3/4-ZEB signaling.
Smurf2 suppresses the metastasis of hepatocellular carcinoma via ubiquitin degradation of Smad2.
Clotrimazole Inhibits HCC Migration and Invasion by Modulating the ERK-p65 Signaling Pathway.
Metformin Ameliorates Epithelial-Mesenchymal Transition of Renal Tubular Epithelial Cells in Diabetes by Increasing Vitamin D Receptor Expression.
Mechanism of Thunberg Fritillaria in treating endometriosis based on network pharmacology and the effect of Peiminine on the MEK/ERK pathway.
LncRNA PCAT7 promotes non-small cell lung cancer progression by activating miR-486-5p/CDK4 axis-mediated cell cycle.
TMEM158 Regulates the Canonical and Non-Canonical Pathways of TGF-β to Mediate EMT in Triple-Negative Breast Cancer.
Sinapine Thiocyanate Inhibits the Proliferation and Mobility of Pancreatic Cancer Cells by Up-Regulating GADD45A.
2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside ameliorates bleomycin-induced pulmonary fibrosis via regulating pro-fibrotic signaling pathways.
NRF2-directed PRPS1 upregulation to promote the progression and metastasis of melanoma.
Therapeutic effect and mechanism of combination therapy with ursolic acid and insulin on diabetic nephropathy in a type I diabetic rat model.
Identification and validation of an immune signature associated with EMT and metabolic reprogramming for predicting prognosis and drug response in bladder cancer.
A comprehensively prognostic and immunological analysis of actin-related protein 2/3 complex subunit 5 in pan-cancer and identification in hepatocellular carcinoma.
TIM-4 in macrophages contributes to nasal polyp formation through the TGF-β1-mediated epithelial to mesenchymal transition in nasal epithelial cells.
The Potential Role of CDH1 as an Oncogene Combined With Related miRNAs and Their Diagnostic Value in Breast Cancer.
ATP-citrate lyase inhibitor improves ectopic lipid accumulation in the kidney in a db/db mouse model.
Dandelion Seed Extract Affects Tumor Progression and Enhances the Sensitivity of Cisplatin in Esophageal Squamous Cell Carcinoma.
Acteoside attenuates RSV-induced lung injury by suppressing necroptosis and regulating metabolism.
Crosstalk of Histone and RNA Modifications Identified a Stromal-Activated Subtype with Poor Survival and Resistance to Immunotherapy in Gastric Cancer.
Neutrophil Extracellular Traps (NETs) Promote Non-Small Cell Lung Cancer Metastasis by Suppressing lncRNA MIR503HG to Activate the NF-κB/NLRP3 Inflammasome Pathway.
KIFC3 Promotes Proliferation, Migration, and Invasion in Colorectal Cancer via PI3K/AKT/mTOR Signaling Pathway.
Gut Dysbiosis Is Associated With the Severity of Cryptogenic Stroke and Enhanced Systemic Inflammatory Response.
S100A4/TCF Complex Transcription Regulation Drives Epithelial-Mesenchymal Transition in Chronic Sinusitis Through Wnt/GSK-3β/β-Catenin Signaling.
NCKAP1 is a Prognostic Biomarker for Inhibition of Cell Growth in Clear Cell Renal Cell Carcinoma.
Comprehensive analysis of a glycolysis and cholesterol synthesis-related genes signature for predicting prognosis and immune landscape in osteosarcoma.
Dysfunction of CCR1(+) decidual macrophages is a potential risk factor in the occurrence of unexplained recurrent pregnancy loss.
Protective effects of mefunidone on ischemia-reperfusion injury/Folic acid-induced acute kidney injury.
METTL3/m(6)A/IFIT2 regulates proliferation, invasion and immunity in esophageal squamous cell carcinoma.
COA3 overexpression promotes non-small cell lung cancer metastasis by reprogramming glucose metabolism.
The homeostatic malfunction of a novel feedback pathway formed by lncRNA021545, miR-330-3p and epiregulin contributes in hepatocarcinoma progression via mediating epithelial-mesenchymal transition.
Decreased RNA m(6)A methylation enhances the process of the epithelial mesenchymal transition and vasculogenic mimicry in glioblastoma.
The N(6)-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2.
Interleukin-17 promotes the development of ovarian cancer through upregulation of MTA1 expression.
RUNX2 facilitates aggressiveness and chemoresistance of triple negative breast cancer cells via activating MMP1.
bub1 as a potential oncogene and a prognostic biomarker for neuroblastoma.
A novel epithelial-mesenchymal transition (EMT)-related gene signature of predictive value for the survival outcomes in lung adenocarcinoma.
Novel LncRNA ZFHX4-AS1 as a Potential Prognostic Biomarker That Affects the Immune Microenvironment in Ovarian Cancer.
The Novel LncRNA WASH5P Inhibits Colorectal Cancer Carcinogenesis via Targeting AKT Signaling Pathway.
Knockdown of USP8 inhibits prostate cancer cell growth, proliferation, and metastasis and promotes docetaxel's activity by suppressing the NF-kB signaling pathway.
OCT4 induces EMT and promotes ovarian cancer progression by regulating the PI3K/AKT/mTOR pathway.
Chordin-Like 1 Regulates Epithelial-to-Mesenchymal Transition and Metastasis via the MAPK Signaling Pathway in Oral Squamous Cell Carcinoma.
Correlation Analysis of Gut Microbiota and Serum Metabolome With Porphyromonas gingivalis-Induced Metabolic Disorders.
Integrated Network Pharmacology and Experimental Verification to Explore the Molecular Mechanism of Hedysarum Multijugum Maxim-Curcumae Rhizoma Herb Pair for Treating Non-Small Cell Lung Cancer.
Agonists Specific for κ-Opioid Receptor Induces Apoptosis of HCC Cells Through Enhanced Endoplasmic Reticulum Stress.
Up-Regulated MISP Is Associated With Poor Prognosis and Immune Infiltration in Pancreatic Ductal Adenocarcinoma.
ACADL Functions as a Tumor Suppressor in Hepatocellular Carcinoma Metastasis by Inhibiting Matrix Metalloproteinase 14.
Loss of Frizzled 9 in Lung Cells Alters Epithelial Phenotype and Promotes Premalignant Lesion Development.
NUF2 Expression Promotes Lung Adenocarcinoma Progression and Is Associated With Poor Prognosis.
Syntenin Regulated by miR-216b Promotes Cancer Progression in Pancreatic Cancer.
N-Glycosylation at Asn291 Stabilizes TIM-4 and Promotes the Metastasis of NSCLC.
Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta gene as a tumour suppressor in stomach adenocarcinoma.
Prognostic biomarker MCP-4 triggers epithelial-mesenchymal transition via the p38 MAPK pathway in ovarian cancer.
Consistent downregulation of the cleft lip/palate-associated genes IRF6 and GRHL3 in carcinomas.
Loss of CMTM6 promotes DNA damage-induced cellular senescence and antitumor immunity.
A long noncoding RNA GTF2IRD2P1 suppresses cell proliferation in bladder cancer by inhibiting the Wnt/β‑catenin signaling pathway.
ATP11A promotes EMT by regulating Numb PRR(L) in pancreatic cancer cells.
CircFGGY Inhibits Cell Growth, Invasion and Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma via Regulating the miR-545-3p/Smad7 Axis.
Targeting MALT1 Suppresses the Malignant Progression of Colorectal Cancer via miR-375/miR-365a-3p/NF-κB Axis.
TAGLN2-Regulated Trophoblast Migration, Invasion and Fusion are Impaired in Preeclampsia.
Heat stress and hypoxia inhibit the secretion of androgens and induce epithelial-to-mesenchymal transition associated with activated TGF-β/Smad signalling in canine cryptorchidism.
GTSE1 promotes tumor growth and metastasis by attenuating of KLF4 expression in clear cell renal cell carcinoma.
Glutamine in suppression of lipopolysaccharide-induced piglet intestinal inflammation: The crosstalk between AMPK activation and mitochondrial function.
Discovery and characterization of heterogeneous and multipotent fibroblast populations isolated from excised cleft lip tissue.
Histone methyltransferase MLL1 drives renal tubular cell apoptosis by p53-dependent repression of E-cadherin during cisplatin-induced acute kidney injury.
TRAF4 Promotes the Proliferation of Glioblastoma by Stabilizing SETDB1 to Activate the AKT Pathway.
MICAL2 contributes to gastric cancer cell migration via Cdc42-dependent activation of E-cadherin/β-catenin signaling pathway.
MicroRNA-20a-5p regulates the epithelial-mesenchymal transition of human hepatocellular carcinoma by targeting RUNX3.
TFAP2C Knockdown Sensitizes Bladder Cancer Cells to Cisplatin Treatment via Regulation of EGFR and NF-κB.
Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.
Exosomal miR-22-3p from Mesenchymal Stem Cells Inhibits the Epithelial-Mesenchymal Transition (EMT) of Melanoma Cells by Regulating LGALS1.
BMP2 promotes lung adenocarcinoma metastasis through BMP receptor 2-mediated SMAD1/5 activation.
HOXA5 inhibits the proliferation of extrahepatic cholangiocarcinoma cells by enhancing MXD1 expression and activating the p53 pathway.
NR2F1 Regulates TGF-β1-Mediated Epithelial-Mesenchymal Transition Affecting Platinum Sensitivity and Immune Response in Ovarian Cancer.
Taraxasterol Inhibits Tumor Growth by Inducing Apoptosis and Modulating the Tumor Microenvironment in Non-Small Cell Lung Cancer.
AHSA1 Promotes Proliferation and EMT by Regulating ERK/CALD1 Axis in Hepatocellular Carcinoma.
Genistein Restricts the Epithelial Mesenchymal Transformation (EMT) and Stemness of Hepatocellular Carcinoma via Upregulating miR-1275 to Inhibit the EIF5A2/PI3K/Akt Pathway.
KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.
CAV2 promotes the invasion and metastasis of head and neck squamous cell carcinomas by regulating S100 proteins.
Inhibition of PTPN21 has antitumor effects in glioma by restraining the EGFR/PI3K/AKT pathway.
Upregulation of miR-520c-3p via hepatitis B virus drives hepatocellular migration and invasion by the PTEN/AKT/NF-κB axis.
Hypoxia-induced polarization of M2 macrophages and C-C motif chemokine ligand 5 secretion promotes the migration and invasion of trophoblasts†.
EP300 promotes renal tubular epithelial cell fibrosis by increasing HIF2α expression in diabetic nephropathy.
Anti-inflammatory potential of stevia residue extract against uric acid-associated renal injury in mice.
PLEK2 promotes cancer stemness and tumorigenesis of head and neck squamous cell carcinoma via the c-Myc-mediated positive feedback loop.
Exosomes derived from mesenchymal stem cells attenuate diabetic kidney disease by inhibiting cell apoptosis and epithelial-to-mesenchymal transition via miR-424-5p.
Bryodulcosigenin attenuates bleomycin-induced pulmonary fibrosis via inhibiting AMPK-mediated mesenchymal epithelial transition and oxidative stress.
Transcription factor YY1 contributes to human melanoma cell growth through modulating the p53 signalling pathway.
Upregulation of Wilms' Tumor 1 in epicardial cells increases cardiac fibrosis in dystrophic mice.
Identification of a five m6A-relevant mRNAs signature and risk score for the prognostication of gastric cancer.
LHX2 facilitates the progression of nasopharyngeal carcinoma via activation of the FGF1/FGFR axis.
Tumor-associated macrophages promote migration and invasion via modulating IL-6/STAT3 signaling in renal cell carcinoma.
Natural shikonin and acetyl-shikonin improve intestinal microbial and protein composition to alleviate colitis-associated colorectal cancer.
Downregulation of exosomal miR-7-5p promotes breast cancer migration and invasion by targeting RYK and participating in the atypical WNT signalling pathway.
Tension of plus-end tracking protein Clip170 confers directionality and aggressiveness during breast cancer migration.
ALG3 Promotes Peritoneal Metastasis of Ovarian Cancer through Increasing Interaction of α1,3-mannosylated uPAR and ADAM8.
LPAR5 confers radioresistance to cancer cells associated with EMT activation via the ERK/Snail pathway.
Local Application of Krill Oil Accelerates the Healing of Artificially Created Wounds in Diabetic Mice.
LMNA Reduced Acquired Resistance to Erlotinib in NSCLC by Reversing the Epithelial-Mesenchymal Transition via the FGFR/MAPK/c-fos Signaling Pathway.
IGF2BP2 Promotes Epithelial to Mesenchymal Transition and Metastasis through Stabilizing HMGA1 mRNA in Gastric Cancer.
Fucoxanthin induces apoptosis and reverses epithelial-mesenchymal transition via inhibiting Wnt/β-catenin pathway in lung adenocarcinoma.
MICALL2 as a substrate of ubiquitinase TRIM21 regulates tumorigenesis of colorectal cancer.
FTO Inhibits Epithelial Ovarian Cancer Progression by Destabilising SNAI1 mRNA through IGF2BP2.
Downregulation of TUSC3 promotes EMT and hepatocellular carcinoma progression through LIPC/AKT axis.
CAMK2N1 has a cancer-suppressive function in colorectal carcinoma via effects on the Wnt/β-catenin pathway.
Isolation, purification and characterization of Pueraria lobata polysaccharide and its effects on intestinal function in cyclophosphamide-treated mice.
Role of non-neuronal cholinergic system in the early stage response of epithelial-mesenchymal transformation related markers in A549 cells induced by coal particles.
Knockdown of TTC9 inhibits the proliferation, migration and invasion, but induces the apoptosis of lung adenocarcinoma cells.
Acyl-CoA thioesterase 9 promotes tumour growth and metastasis through reprogramming of fatty acid metabolism in hepatocellular carcinoma.
Targeting epiregulin in the treatment-damaged tumor microenvironment restrains therapeutic resistance.
Endophilin A2 protects against renal fibrosis by targeting TGF-β/Smad signaling.
Metabolomic Analysis Reveals that SPHK1 Promotes Oral Squamous Cell Carcinoma Progression through NF-κB Activation.
Legumain affects the PI3K/AKT tumor progression pathway in retinoblastoma.
MYPT1 inhibits the metastasis of renal clear cell carcinoma via the MAPK8/N-cadherin pathway.
Knockdown of SOX9 alleviates tracheal fibrosis through the Wnt/β-catenin signaling pathway.
SIRT2 promotes the viability, invasion and metastasis of osteosarcoma cells by inhibiting the degradation of Snail.
MK-2206 Alleviates Renal Fibrosis by Suppressing the Akt/mTOR Signaling Pathway In Vivo and In Vitro.
Follistatin Is a Novel Chemoattractant for Migration and Invasion of Placental Trophoblasts of Mice.
Ovarian tumorB1-mediated heat shock transcription factor 1 deubiquitination is critical for glycolysis and development of endometriosis.
METTL1 drives tumor progression of bladder cancer via degrading ATF3 mRNA in an m(7)G-modified miR-760-dependent manner.
Palmitic Acid Promotes Lung Metastasis of Melanomas via the TLR4/TRIF-Peli1-pNF-κB Pathway.
FGF2 isoforms play distinct roles in tubular epithelial-to-mesenchymal transition in diabetic nephropathy.
Design and biological features of platinum (II) complexes with 3-hydroxy-3-(Trifluoromethyl)cyclobutane-1,1-Dicarboxylate as a leaving ligand.
MiR-30e-3p inhibits gastric cancer development by negatively regulating THO complex 2 and PI3K/AKT/mTOR signaling.
N-glycosylation of CD82 at Asn157 is required for suppressing migration and invasion by reversing EMT via Wnt/β-catenin pathway in colon cancer.
NAP1L5 targeting combined with MYH9 Inhibit HCC progression through PI3K/AKT/mTOR signaling pathway.
Circular RNA hsa_circ_0051040 Promotes Hepatocellular Carcinoma Progression by Sponging miR-569 and Regulating ITGAV Expression.
Cancer-associated fibroblasts promote the stemness and progression of renal cell carcinoma via exosomal miR-181d-5p.
KIF17 maintains the epithelial phenotype of breast cancer cells and curbs tumour metastasis.
The inhibition of centromere protein K causes anticancer effects in breast carcinoma via effects on the FAK/PI3K/AKT/mTOR pathway.
Sinapic acid inhibits pancreatic cancer proliferation, migration, and invasion via downregulation of the AKT/Gsk-3β signal pathway.
Development of Clinical-Grade Antibodies against Tumor-Specific Mutations to Target Neuroblastoma.
RhoGDI2 induced malignant phenotypes of pancreatic cancer cells via regulating Snail expression.
miR-217-5p suppresses epithelial-mesenchymal transition and the NF-κB signaling pathway in breast cancer via targeting of metadherin.
Exosomal MMP-1 transfers metastasis potential in triple-negative breast cancer through PAR1-mediated EMT.
Kinesin family member 23, regulated by FOXM1, promotes triple negative breast cancer progression via activating Wnt/β-catenin pathway.
Forkhead Box q1 promotes invasion and metastasis in colorectal cancer by activating the epidermal growth factor receptor pathway.
FAM126A interacted with ENO1 mediates proliferation and metastasis in pancreatic cancer via PI3K/AKT signaling pathway.
Spatiotemporal Gene Expression Regions along the Anterior-Posterior Axis in Mouse Embryos before and after Palatal Elevation.
Multinucleated Retinal Pigment Epithelial Cells Adapt to Vision and Exhibit Increased DNA Damage Response.
FAT10 promotes chemotherapeutic resistance in pancreatic cancer by inducing epithelial-mesenchymal transition via stabilization of FOXM1 expression.
Targeting dual-specificity tyrosine phosphorylation-regulated kinase 2 with a highly selective inhibitor for the treatment of prostate cancer.
MiR-135a-5p suppresses trophoblast proliferative, migratory, invasive, and angiogenic activity in the context of unexplained spontaneous abortion.
Therapeutic Effect of Platelet-Rich Plasma Improves Bladder Overactivity in the Pathogenesis of Ketamine-Induced Ulcerative Cystitis in a Rat Model.
[P4HA2 promotes occurrence and progression of liver cancer by regulating the PI3K/Akt/mTOR signaling pathway].
A comprehensive analysis of potential gastric cancer prognostic biomarker ITGBL1 associated with immune infiltration and epithelial-mesenchymal transition.
Cancer associated fibroblast-derived CCL5 promotes hepatocellular carcinoma metastasis through activating HIF1α/ZEB1 axis.
Construction of gastric cancer patient-derived organoids and their utilization in a comparative study of clinically used paclitaxel nanoformulations.
TMCO1 expression promotes cell proliferation and induces epithelial-mesenchymal transformation in human gliomas.
CXCL13 as a Novel Immune Checkpoint for Regulatory B Cells and Its Role in Tumor Metastasis.
The enhancer RNA ADCY10P1 is associated with the progression of ovarian cancer.
VCP interaction with HMGB1 promotes hepatocellular carcinoma progression by activating the PI3K/AKT/mTOR pathway.
Stanniocalcin2 inhibits the epithelial-mesenchymal transition and invasion of trophoblasts via activation of autophagy under high-glucose conditions.
Downregulated RRS1 inhibits invasion and metastasis of BT549 through RPL11‑c‑Myc‑SNAIL axis.
LACTB suppresses carcinogenesis in lung cancer and regulates the EMT pathway.
Selenium Deficiency Leads to Changes in Renal Fibrosis Marker Proteins and Wnt/β-Catenin Signaling Pathway Components.
In situ injectable hydrogel-loaded drugs induce anti-tumor immune responses in melanoma immunochemotherapy.
LINC00244 suppresses cell growth and metastasis in hepatocellular carcinoma by downregulating programmed cell death ligand 1.
Inhibition of translocator protein 18 kDa suppressed the progression of glioma via the ELAV-like RNA-binding protein 1/MAPK-activated protein kinase 3 axis.
YB1 associates with oncogenetic roles and poor prognosis in nasopharyngeal carcinoma.
The miR-345-3p/PPP2CA signaling axis promotes proliferation and invasion of breast cancer cells.
CircESRP1 enhances metastasis and epithelial-mesenchymal transition in endometrial cancer via the miR-874-3p/CPEB4 axis.
Heat Stress Impairs Maternal Endometrial Integrity and Results in Embryo Implantation Failure by Regulating Transport-Related Gene Expression in Tongcheng Pigs.
lncRNA SNHG26 promoted the growth, metastasis, and cisplatin resistance of tongue squamous cell carcinoma through PGK1/Akt/mTOR signal pathway.
Restraint of chaperonin containing T-complex protein-1 subunit 3 has antitumor roles in non-small cell lung cancer via affection of YAP1.
Pan-cancer analysis, cell and animal experiments revealing TEAD4 as a tumor promoter in ccRCC.
Autophagy-associated circRNA circATG7 facilitates autophagy and promotes pancreatic cancer progression.
Knockdown of long noncoding RNA MIAT attenuates cigarette smoke-induced airway remodeling by downregulating miR-29c-3p-HIF3A axis.
Bile acids promote the caveolae-associated entry of swine acute diarrhea syndrome coronavirus in porcine intestinal enteroids.
Blockade of TMEM16A protects against renal fibrosis by reducing intracellular Cl(-) concentration.
Circular RNA circ_0001459 accelerates hepatocellular carcinoma progression via the miR-6165/IGF1R axis.
A neutrophil-mediated carrier regulates tumor stemness by inhibiting autophagy to prevent postoperative triple-negative breast cancer recurrence and metastasis.
Circ_0005231 promotes the progression of esophageal squamous cell carcinoma via sponging miR-383-5p and regulating KIAA0101.
Increased susceptibility of irradiated mice to Aspergillus fumigatus infection via NLRP3/GSDMD pathway in pulmonary bronchial epithelia.
Hydroxychloroquine alleviates renal interstitial fibrosis by inhibiting the PI3K/Akt signaling pathway.
Pharmacological Inhibition of Endogenous Hydrogen Sulfide Attenuates Breast Cancer Progression.
Iloprost requires the Frizzled-9 receptor to prevent lung cancer.
The MIR100HG/miR-29a-3p/Tab1 axis modulates TGF-β1-induced fibrotic changes in type II alveolar epithelial cells BLM-caused lung fibrogenesis in mice.
Phenazine derivatives attenuate the stemness of breast cancer cells through triggering ferroptosis.
A signature of circadian rhythm genes in driving anaplastic thyroid carcinoma malignant progression.
The ETS1-LINC00278 negative feedback loop plays a role in COL4A1/COL4A2 regulation in laryngeal squamous cell carcinoma.
Methylation-mediated expression of SPARC is correlated with tumor progression and poor prognosis of breast cancer.
LncRNA BACE1-AS promotes the progression of osteosarcoma through miR-762/SOX7 axis.
Overexpression of ERCC6L correlates with poor prognosis and confers malignant phenotypes of lung adenocarcinoma.
Microfluidic platform for studying the anti-cancer effect of ursolic acid on tumor spheroid.
SESN1, negatively regulated by miR-377-3p, suppresses invasive growth of head and neck squamous cell carcinoma by interaction with SMAD3.
Hypoxia-inducible factor-2α promotes EMT in esophageal squamous cell carcinoma through the Notch pathway.
Autophagy deficiency promotes lung metastasis of prostate cancer via stabilization of TWIST1.
LncRNA HOTTIP PROMOTES OVARIAN CANCER CELL INVASION AND METASTASIS BY STABILIZING HIF-1α IN THE ANOXIC CELLULAR MICROENVIRONMENT.
Gankyrin modulated non-small cell lung cancer progression via glycolysis metabolism in a YAP1-dependent manner.
Sestrin2 remedies podocyte injury via orchestrating TSP-1/TGF-β1/Smad3 axis in diabetic kidney disease.
Discovery of Novel Phosphoinositide-3-Kinase α Inhibitors with High Selectivity, Excellent Bioavailability, and Long-Acting Efficacy for Gastric Cancer.
Ginsenoside Rh4 Suppresses Metastasis of Esophageal Cancer and Expression of c-Myc via Targeting the Wnt/β-Catenin Signaling Pathway.
Cancer cells corrupt normal epithelial cells through miR-let-7c-rich small extracellular vesicle-mediated downregulation of p53/PTEN.
Hyaluronic Acid Modified Nanostructured Lipid Carrier for Targeting Delivery of Kaempferol to NSCLC: Preparation, Optimization, Characterization, and Performance Evaluation In Vitro.
KIFC3 promotes proliferation, migration and invasion of esophageal squamous cell carcinoma cells by activating EMT and β-catenin signaling.
Expansion of mouse castration-resistant intermediate prostate stem cells in vitro.
RBM47 inhibits hepatocellular carcinoma progression by targeting UPF1 as a DNA/RNA regulator.
Rosmarinic Acid Decreases the Malignancy of Pancreatic Cancer Through Inhibiting Gli1 Signaling.
Histone deacetylase 6-mediated downregulation of TMEM100 expedites the development and progression of non-small cell lung cancer.
IGF2BP3 promotes cell metastasis and is associated with poor patient survival in nasopharyngeal carcinoma.
Jolkinolide B alleviates renal fibrosis via anti-inflammation and inhibition of epithelial-mesenchymal transition in unilateral ureteral obstruction mice.
Deubiquitinase USP13 promotes the epithelial-mesenchymal transition and metastasis in gastric cancer by maintaining Snail protein.
MICAL1 inhibits colorectal cancer cell migration and proliferation by regulating the EGR1/β-catenin signaling pathway.
Etoposide-induced protein 2.4 ameliorates high glucose-induced epithelial-mesenchymal transition by activating adenosine monophosphate-activated protein kinase pathway in renal tubular cells.
circUSP34 accelerates osteosarcoma malignant progression by sponging miR-16-5p.
Inhibition of the proliferation, invasion, migration, and epithelial-mesenchymal transition of prostate cancer cells through the action of ATP1A2 on the TGF-β/Smad pathway.
YTHDF3 facilitates triple-negative breast cancer progression and metastasis by stabilizing ZEB1 mRNA in an m(6)A-dependent manner.
HSP90AB1 Promotes the Proliferation, Migration, and Glycolysis of Head and Neck Squamous Cell Carcinoma.
G-protein Coupled Receptor 34 Promotes Gliomagenesis by Inducing Proliferation and Malignant Phenotype via TGF-Beta/Smad Signaling Pathway.
miR-498 Targets UBE2T to Inhibit the Proliferation of Malignant Melanoma Cells.
STK25 enhances hepatocellular carcinoma progression through the STRN/AMPK/ACC1 pathway.
Circ_0078607 inhibits the progression of ovarian cancer via regulating the miR-32-5p/SIK1 network.
Circular RNA circCSPP1 promotes the occurrence and development of colon cancer by sponging miR-431 and regulating ROCK1 and ZEB1.
HERC3 regulates epithelial-mesenchymal transition by directly ubiquitination degradation EIF5A2 and inhibits metastasis of colorectal cancer.
lncRNA PCAT1 might coordinate ZNF217 to promote CRC adhesion and invasion through regulating MTA2/MTA3/Snai1/E-cadherin signaling.
Extracellular vesicles released by non-small cell lung cancer cells drive invasion and permeability in non-tumorigenic lung epithelial cells.
Identification of Pyruvate Carboxylase as the Cellular Target of Natural Bibenzyls with Potent Anticancer Activity against Hepatocellular Carcinoma via Metabolic Reprogramming.
ZC3H15 promotes glioblastoma progression through regulating EGFR stability.
CACNA1B facilitates breast cancer cell growth and migration by regulating cyclin D1 and EMT: the implication of CACNA1B in breast cancer.
FGD3 binds with HSF4 to suppress p65 expression and inhibit pancreatic cancer progression.
The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer.
Ginkgo biloba Extract Inhibited Cell Proliferation and Invasion by Stimulating TET2 Expression Through miR-29a in Colorectal Carcinoma Cells.
MiR-4521 plays a tumor repressive role in growth and metastasis of hepatocarcinoma cells by suppressing phosphorylation of FAK/AKT pathway via targeting FAM129A.
The cancer-testis lncRNA lnc-CTHCC promotes hepatocellular carcinogenesis by binding hnRNP K and activating YAP1 transcription.
Dihydrotestosterone through blockade of TGF-β/Smad signaling mediates the anti-fibrosis effect under hypoxia in canine Sertoli cells.
Nc886 promotes renal cancer cell drug-resistance by enhancing EMT through Rock2 phosphorylation-mediated β-catenin nuclear translocation.
Cancer-associated fibroblasts promote tumor progression by lncRNA-mediated RUNX2/GDF10 signaling in oral squamous cell carcinoma.
Ubiquitin-specific peptidase 2 inhibits epithelial-mesenchymal transition in clear cell renal cell carcinoma metastasis by downregulating the NF-κB pathway.
Foxhead box D1 promotes the partial epithelial-to-mesenchymal transition of laryngeal squamous cell carcinoma cells via transcriptionally activating the expression of zinc finger protein 532.
Hyperglycemia induces miR-26-5p down-regulation to overexpress PFKFB3 and accelerate epithelial-mesenchymal transition in gastric cancer.
tRF-19-W4PU732S promotes breast cancer cell malignant activity by targeting inhibition of RPL27A (ribosomal protein-L27A).
MiR-187 regulates the proliferation, migration and invasion of human trophoblast cells by repressing BCL6-mediated activation of PI3K/AKT signaling.
TCOF1 coordinates oncogenic activation and rRNA production and promotes tumorigenesis in HCC.
HDAC9 Contributes to Serous Ovarian Cancer Progression through Regulating Epithelial-Mesenchymal Transition.
Effects of Exopolysaccharides from Lactiplantibacillus plantarum JLAU103 on Intestinal Immune Response, Oxidative Stress, and Microbial Communities in Cyclophosphamide-Induced Immunosuppressed Mice.
YTHDF1 promotes breast cancer progression by facilitating FOXM1 translation in an m6A-dependent manner.
Ginkgo biloba leaf extract mitigates cisplatin-induced chronic renal interstitial fibrosis by inhibiting the epithelial-mesenchymal transition of renal tubular epithelial cells mediated by the Smad3/TGF-β1 and Smad3/p38 MAPK pathways.
Programmed death-ligand 1 signaling and expression are reversible by lycopene via PI3K/AKT and Raf/MEK/ERK pathways in tongue squamous cell carcinoma.
ZHX2 inhibits thyroid cancer metastasis through transcriptional inhibition of S100A14.
Ginsenoside Rh4 Suppressed Metastasis of Lung Adenocarcinoma via Inhibiting JAK2/STAT3 Signaling.
A novel immune-related lncRNA pair signature for prognostic prediction and immune response evaluation in gastric cancer: a bioinformatics and biological validation study.
ID2 inhibits lung adenocarcinoma cell malignant behaviors by inhibiting the activation of the PI3K/AKT/mTOR signaling pathway.
CircCERS6 Suppresses the Development of Epithelial Ovarian Cancer Through Mediating miR-630/RASSF8.
Study on the biological mechanism of urolithin a on nasopharyngeal carcinoma in vitro.
Anti-EMT and anti-fibrosis effects of protocatechuic aldehyde in renal proximal tubular cells and the unilateral ureteral obstruction animal model.
PD-L1/PD-L1 signalling promotes colorectal cancer cell migration ability through RAS/MEK/ERK.
Inhibition of Circ-Snrk ameliorates apoptosis and inflammation in acute kidney injury by regulating the MAPK pathway.
Relaxin inhibits renal fibrosis and the epithelial-to-mesenchymal transition via the Wnt/β-catenin signaling pathway.
Cystathionine γ-lyase mediates cell proliferation, migration, and invasion of nasopharyngeal carcinoma.
CUL4B increases platinum-based drug resistance in colorectal cancer through EMT: A study in its mechanism.
IRF2-ferroptosis related gene is associated with prognosis and EMT in gliomas.
ALG2 inhibits the epithelial-to-mesenchymal transition and stemness of ovarian granulosa cells through the Wnt/β-catenin signaling pathway in polycystic ovary syndrome.
CircRNA PVT1 modulated cell migration and invasion through Epithelial-Mesenchymal Transition (EMT) mediation in gastric cancer through miR-423-5p/Smad3 pathway.
Genomic and expressional dynamics of ovarian cancer cell lines in PARPi treatment revealed mechanisms of acquired resistance.
Carbon dots enhance extracellular matrix secretion for dentin-pulp complex regeneration through PI3K/Akt/mTOR pathway-mediated activation of autophagy.
Artemisitene suppresses rheumatoid arthritis progression via modulating METTL3-mediated N6-methyladenosine modification of ICAM2 mRNA in fibroblast-like synoviocytes.
Silencing of lncRNA SNHG17 inhibits the tumorigenesis of epithelial ovarian cancer through regulation of miR-485-5p/AKT1 axis.
Exosome-transmitted S100A4 induces immunosuppression and non-small cell lung cancer development by activating STAT3.
Construction and validation of a prognostic model for osteosarcoma patients based on autophagy-related genes.
lncRNA ZNRD1-AS1 promotes malignant lung cell proliferation, migration, and angiogenesis via the miR-942/TNS1 axis and is positively regulated by the m(6)A reader YTHDC2.
FAT4 activation inhibits epithelial-mesenchymal transition (EMT) by promoting autophagy in H2228/Cer cells.
Krüppel-like Factor 13 Promotes HCC Progression by Transcriptional Regulation of HMGCS1-mediated Cholesterol Synthesis.
Dihydromyricetin Attenuates High-Intensity Exercise-Induced Intestinal Barrier Dysfunction Associated with the Modulation of the Phenotype of Intestinal Intraepithelial Lymphocytes.
Increased expression of miR-194-5p through the circPVRL3/miR-194-5p/SOCS2 axis promotes proliferation and metastasis in pancreatic ductal adenocarcinoma by activating the PI3K/AKT signaling pathway.
A multifunctional black phosphorus-based adhesive patch intrinsically induces partial EMT for effective burn wound healing.
Novel shikonin derivatives suppress cell proliferation, migration and induce apoptosis in human triple-negative breast cancer cells via regulating PDK1/PDHC axis.
Identification of endocrine-disrupting chemicals targeting the genes and pathways of genital anomalies in males.
FTO mediated ERBB2 demethylation promotes tumor progression in esophageal squamous cell carcinoma cells.
Suppression of rhomboid domain-containing 1 produces anticancer effects in pancreatic adenocarcinoma through affection of the AKT/GSK-3β/β-catenin pathway.
XIST sponges miR-320d to promote chordoma progression by regulating ARF6.
Ferrostatin‑1 alleviates oxalate‑induced renal tubular epithelial cell injury, fibrosis and calcium oxalate stone formation by inhibiting ferroptosis.
Downstream Neighbor of Son Overexpression is Associated With Breast Cancer Progression and a Poor Prognosis.
Agmatinase facilitates the tumorigenesis of pancreatic adenocarcinoma through the TGFβ/Smad pathway.
Nav1.6 promotes the progression of human follicular thyroid carcinoma cells via JAK-STAT signaling pathway.
Forkhead box A2 transcriptionally activates hsa-let-7 g to inhibit hypoxia-induced epithelial-mesenchymal transition by targeting c14orf28 in colorectal cancer.
Design, Synthesis and Anti-Tumor Activity Evaluation of Novel 3,4-(Methylenedioxy)cinnamic Acid Amide-Dithiocarbamate Derivatives.
HIF-1α induced NID1 expression promotes pulmonary metastases via the PI3K-AKT pathway in salivary gland adenoid cystic carcinoma.
LncRNA SNHG11 promotes the malignant transformation of human bronchial epithelial cells induced by beryllium sulfate.
PEBP4 Directs the Malignant Behavior of Hepatocellular Carcinoma Cells via Regulating mTORC1 and mTORC2.
Long noncoding RNA CERS6-AS1 modulates glucose metabolism and tumor progression in hepatocellular carcinoma by promoting the MDM2/p53 signaling pathway.
The LINC00623/NAT10 signaling axis promotes pancreatic cancer progression by remodeling ac4C modification of mRNA.
Construction of a novel model based on cell-in-cell-related genes and validation of KRT7 as a biomarker for predicting survival and immune microenvironment in pancreatic cancer.
FAM107A Inactivation Associated with Promoter Methylation Affects Prostate Cancer Progression through the FAK/PI3K/AKT Pathway.
miR-596-3p suppresses brain metastasis of non-small cell lung cancer by modulating YAP1 and IL-8.
PDCD10 promotes the aggressive behaviors of pituitary adenomas by up-regulating CXCR2 and activating downstream AKT/ERK signaling.
Jianpi Huayu decoction inhibits the epithelial-mesenchymal transition of hepatocellular carcinoma cells by suppressing exosomal miR-23a-3p/Smad signaling.
SEC14L3 plays a tumor-suppressive role in breast cancer through a Wnt/β-catenin-related way.
Downregulation of CPT2 promotes proliferation and inhibits apoptosis through p53 pathway in colorectal cancer.
EML4-ALK G1202R mutation induces EMT and confers resistance to ceritinib in NSCLC cells via activation of STAT3/Slug signaling.
Hsa_circRNA_0017620 regulated cell progression of non-small-cell lung cancer via miR-520a-5p/KRT5 axis.
Myricetin reverses epithelial-endothelial transition and inhibits vasculogenic mimicry and angiogenesis of hepatocellular carcinoma by directly targeting PAR1.
Tumor-specific nitric oxide generator to amplify peroxynitrite based on highly penetrable nanoparticles for metastasis inhibition and enhanced cancer therapy.
Apatinib inhibits tumour progression and promotes antitumour efficacy of cytotoxic drugs in oesophageal squamous cell carcinoma.
Gelsolin impairs barrier function in pancreatic ductal epithelial cells by actin filament depolymerization in hypertriglyceridemia-induced pancreatitis in vitro.
Epiplakin1 promotes the progression of esophageal squamous cell carcinoma by activating the PI3K-AKT signaling pathway.
circHIPK3 regulates cell proliferation and migration by sponging microRNA-124 and regulating serine/threonine kinase 3 expression in esophageal squamous cell carcinoma.
Terpinen-4-ol inhibits the proliferation and mobility of pancreatic cancer cells by downregulating Rho-associated coiled-coil containing protein kinase 2.
The long non-coding RNA T cell leukemia homeobox 1 neighbor enhances signal transducer and activator of transcription 5A phosphorylation to promote colon cancer cell invasion, migration, and metastasis.
Ginsenoside Rh4 Suppresses Metastasis of Gastric Cancer via SIX1-Dependent TGF-β/Smad2/3 Signaling Pathway.
Mechanosensitive Piezo1 channels mediate renal fibrosis.
TIM-1 promotes proliferation and metastasis, and inhibits apoptosis, in cervical cancer through the PI3K/AKT/p53 pathway.
Rhein Improves Renal Fibrosis by Restoring Cpt1a-Mediated Fatty Acid Oxidation through SirT1/STAT3/twist1 Pathway.
Biomimetic Nanomedicine-Triggered in Situ Vaccination for Innate and Adaptive Immunity Activations for Bacterial Osteomyelitis Treatment.
Brusatol inhibits the growth of renal cell carcinoma by regulating the PTEN/PI3K/AKT pathway.
ORP5 promotes tumor metastasis via stabilizing c-Met in renal cell carcinoma.
Overexpression of GATA5 Inhibits Prostate Cancer Progression by Regulating PLAGL2 via the FAK/PI3K/AKT Pathway.
Epigenetic Deregulation of Protein Tyrosine Kinase 6 Promotes Carcinogenesis of Oral Squamous Cell Carcinoma.
METTL3-mediated m6A modification of STEAP2 mRNA inhibits papillary thyroid cancer progress by blocking the Hedgehog signaling pathway and epithelial-to-mesenchymal transition.
Hexachlorophene, a selective SHP2 inhibitor, suppresses proliferation and metastasis of KRAS-mutant NSCLC cells by inhibiting RAS/MEK/ERK and PI3K/AKT signaling pathways.
Silencing of Nudix type 5 represses proliferation and invasion and enhances chemosensitivity of gastric carcinoma cells by affecting the AKT/GSK-3β/β-catenin pathway.
Quantum dots bind nanosheet to promote nanomaterial stability and resist endotoxin-induced fibrosis and PM(2.5)-induced pneumonia.
m6A Modification-Mediated DUXAP8 Regulation of Malignant Phenotype and Chemotherapy Resistance of Hepatocellular Carcinoma Through miR-584-5p/MAPK1/ERK Pathway Axis.
Nxhl Controls Angiogenesis by Targeting VE-PTP Through Interaction With Nucleolin.
PRDM16 Inhibits Cell Proliferation and Migration via Epithelial-to-Mesenchymal Transition by Directly Targeting Pyruvate Carboxylase in Papillary Thyroid Cancer.
Lack of IRF6 Disrupts Human Epithelial Homeostasis by Altering Colony Morphology, Migration Pattern, and Differentiation Potential of Keratinocytes.
Cathelicidin-WA Protects Against LPS-Induced Gut Damage Through Enhancing Survival and Function of Intestinal Stem Cells.
Melatonin Attenuates Chromium (VI)-Induced Spermatogonial Stem Cell/Progenitor Mitophagy by Restoration of METTL3-Mediated RNA N(6)-Methyladenosine Modification.
Artemisia argyi Essential Oil Inhibits Hepatocellular Carcinoma Metastasis via Suppression of DEPDC1 Dependent Wnt/β-Catenin Signaling Pathway.
LINC00511/miRNA-143-3p Modulates Apoptosis and Malignant Phenotype of Bladder Carcinoma Cells via PCMT1.
Circular RNA circSIPA1L1 Contributes to Osteosarcoma Progression Through the miR-411-5p/RAB9A Signaling Pathway.
USP36-Mediated Deubiquitination of DOCK4 Contributes to the Diabetic Renal Tubular Epithelial Cell Injury via Wnt/β-Catenin Signaling Pathway.
MicroRNA-15a Carried by Mesenchymal Stem Cell-Derived Extracellular Vesicles Inhibits the Immune Evasion of Colorectal Cancer Cells by Regulating the KDM4B/HOXC4/PD-L1 Axis.
ENC1 Facilitates Colorectal Carcinoma Tumorigenesis and Metastasis via JAK2/STAT5/AKT Axis-Mediated Epithelial Mesenchymal Transition and Stemness.
JMJD1A/NR4A1 Signaling Regulates the Procession of Renal Tubular Epithelial Interstitial Fibrosis Induced by AGEs in HK-2.
Comprehensive Analysis of the Potential Immune-Related Biomarker Transporter Associated With Antigen Processing 1 That Inhibits Metastasis and Invasion of Ovarian Cancer Cells.
The Gut Microbiota Activates AhR Through the Tryptophan Metabolite Kyn to Mediate Renal Cell Carcinoma Metastasis.
Transcriptome Differences in Pig Tracheal Epithelial Cells in Response to Pasteurella Multocida Infection.
MicroRNA-653-5p Promotes Gastric Cancer Proliferation and Metastasis by Targeting the SOCS6-STAT3 Pathway.
Acyl-CoA Thioesterase 7 is Transcriptionally Activated by Krüppel-Like Factor 13 and Promotes the Progression of Hepatocellular Carcinoma.
Inositol Hexakisphosphate and Inositol Enhance the Inhibition of Colorectal Cancer Growth and Liver Metastasis by Capecitabine in a Mouse Model.
KCNN4 promotes the progression of lung adenocarcinoma by activating the AKT and ERK signaling pathways.
Qingjie Fuzheng Granule Inhibits EMT and Induces Autophagy in Colorectal Cancer via mTOR Signaling Pathways.
Human Tissue Kallikrein 1 Is Downregulated in Elderly Human Prostates and Possesses Potential In Vitro Antioxidative and Antifibrotic Effects in Rodent Prostates.
Network Pharmacology-Based Mechanistic Investigation of Jinshui Huanxian Formula Acting on Idiopathic Pulmonary Fibrosis.
PP2 Ameliorates Renal Fibrosis by Regulating the NF-κB/COX-2 and PPARγ/UCP2 Pathway in Diabetic Mice.
General Control of Amino Acid Synthesis 5-Like 1-Mediated Acetylation of Manganese Superoxide Dismutase Regulates Oxidative Stress in Diabetic Kidney Disease.
ARHGEF10L Promotes Cervical Tumorigenesis via RhoA-Mediated Signaling.
Ginkgo Biloba Extract EGB761 Ameliorates the Extracellular Matrix Accumulation and Mesenchymal Transformation of Renal Tubules in Diabetic Kidney Disease by Inhibiting Endoplasmic Reticulum Stress.
POU2F1 Promotes Cell Viability and Tumor Growth in Gastric Cancer through Transcriptional Activation of lncRNA TTC3-AS1.
Therapeutic Potential of RTA 404 in Human Brain Malignant Glioma Cell Lines via Cell Cycle Arrest via p21/AKT Signaling.
Release of HMGB1 in Podocytes Exacerbates Lipopolysaccharide-Induced Acute Kidney Injury.
Cysteine-Rich Intestinal Protein 1 Served as an Epithelial Ovarian Cancer Marker via Promoting Wnt/β-Catenin-Mediated EMT and Tumour Metastasis.
Trefoil Factor 3 Inhibits Thyroid Cancer Cell Progression Related to IL-6/JAK/STAT3 Signaling Pathway.
miR-149 Suppresses the Proliferation and Metastasis of Human Gastric Cancer Cells by Targeting FOXC1.
NSE, positively regulated by LINC00657-miR-93-5p axis, promotes small cell lung cancer (SCLC) invasion and epithelial-mesenchymal transition (EMT) process.
NEK2 plays an active role in Tumorigenesis and Tumor Microenvironment in Non-Small Cell Lung Cancer.
ITGB1 enhances the Radioresistance of human Non-small Cell Lung Cancer Cells by modulating the DNA damage response and YAP1-induced Epithelial-mesenchymal Transition.
Cyclovirobuxine inhibits the progression of clear cell renal cell carcinoma by suppressing the IGFBP3-AKT/STAT3/MAPK-Snail signalling pathway.
Downregulation of m(6)A Reader YTHDC2 Promotes the Proliferation and Migration of Malignant Lung Cells via CYLD/NF-κB Pathway.
Hypoxia stimulates the migration and invasion of osteosarcoma via up-regulating the NUSAP1 expression.
Delivery of Rapamycin by Liposomes Synergistically Enhances the Chemotherapy Effect of 5-Fluorouracil on Colorectal Cancer.
Wogonin Alleviates Kidney Tubular Epithelial Injury in Diabetic Nephropathy by Inhibiting PI3K/Akt/NF-κB Signaling Pathways.
SIRT6 inhibits metastasis by suppressing SNAIL expression in nasopharyngeal carcinoma cells.
TEAD4 as a Prognostic Marker Promotes Cell Migration and Invasion of Urinary Bladder Cancer via EMT.
LncRNA UCID Promotes Hepatocellular Carcinoma Metastasis via Stabilization of Snail.
XBP1s Acts as a Tumor Suppressor to Inhibit the EMT Process and Metastasis of Papillary Thyroid Cancer.
LncRNA IGFL2-AS1 Promotes the Proliferation, Migration, and Invasion of Colon Cancer Cells and is Associated with Patient Prognosis.
Columbamine-Mediated PTEN/AKT Signal Pathway Regulates the Progression of Glioma.
Normal Basal Epithelial Cells Stimulate the Migration and Invasion of Prostate Cancer Cell RM-1 by TGF-β1/STAT3 Axis in vitro.
GTW inhibits the Epithelial to Mesenchymal Transition of Epithelial Ovarian Cancer via ILK/AKT/GSK3β/Slug Signalling Pathway.
JMJD8 Promotes Malignant Progression of Lung Cancer by Maintaining EGFR Stability and EGFR/PI3K/AKT Pathway Activation.
Nogo-B receptor is required for stabilizing TGF-β type I receptor and promotes the TGF-β1-induced epithelial-to-mesenchymal transition of non-small cell lung cancer.
Linc01513 inhibits the malignant potential of Nasopharyngeal carcinoma by binding to PTBP1.
Keratin 80 regulated by miR-206/ETS1 promotes tumor progression via the MEK/ERK pathway in ovarian cancer.
Shikonin suppresses the epithelial-to-mesenchymal transition by downregulating NHE1 in bladder cancer cells.
Dihydromyricetin Inhibits Tumor Growth and Epithelial-Mesenchymal Transition through regulating miR-455-3p in Cholangiocarcinoma.
SNX-2112 Induces Apoptosis and Inhibits Proliferation, Invasion, and Migration of Non-Small Cell Lung Cancer by Downregulating Epithelial-Mesenchymal Transition via the Wnt/β-Catenin Signaling Pathway.
Demethylzelasteral inhibits proliferation and EMT via repressing Wnt/β-catenin signaling in esophageal squamous cell carcinoma.
Dextran Sulfate Effects EMT of Human Gastric Cancer Cells by Reducing HIF-1α/ TGF-β.
NKCC1 promotes proliferation, invasion and migration in human gastric cancer cells via activation of the MAPK-JNK/EMT signaling pathway.
Hypoxia-Induced miR-378a-3p Inhibits Osteosarcoma Invasion and Epithelial-to-Mesenchymal Transition via BYSL Regulation.
The Protective Effects of Zornia diphylla (L.) Pers. Against Acute Liver Injury Induced by Carbon Tetrachloride in Mice.
The ALDH Family Contributes to Immunocyte Infiltration, Proliferation and Epithelial-Mesenchymal Transformation in Glioma.
Transcriptome-Based Network Analysis Reveals Hirudin Potentiates Anti-Renal Fibrosis Efficacy in UUO Rats.
Taxus wallichiana var. chinensis (Pilg.) Florin Aqueous Extract Suppresses the Proliferation and Metastasis in Lung Carcinoma via JAK/STAT3 Signaling Pathway.
CXCL5 Downregulation in Villous Tissue Is Correlated With Recurrent Spontaneous Abortion.
Decreased USP2a Expression Inhibits Trophoblast Invasion and Associates With Recurrent Miscarriage.
Mefunidone Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice.
Oxymatrine Synergistically Enhances Doxorubicin Anticancer Effects in Colorectal Cancer.
AGR3 Regulates Airway Epithelial Junctions in Patients with Frequent Exacerbations of COPD.
Autophagic Inhibition of Caveolin-1 by Compound Phyllanthus urinaria L. Activates Ubiquitination and Proteasome Degradation of β-catenin to Suppress Metastasis of Hepatitis B-Associated Hepatocellular Carcinoma.
PLAU Promotes Cell Proliferation and Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma.
Pharmacologic Targeting of BET Proteins Attenuates Hyperuricemic Nephropathy in Rats.
COE Inhibits Vasculogenic Mimicry by Targeting EphA2 in Hepatocellular Carcinoma, a Research Based on Proteomics Analysis.
XMD-17-51 Inhibits DCLK1 Kinase and Prevents Lung Cancer Progression.
N6-methyladenosine-induced circ1662 promotes metastasis of colorectal cancer by accelerating YAP1 nuclear localization.
3'untranslated regions (3'UTR) of Gelsolin mRNA displays anticancer effects in non-small cell lung cancer (NSCLC) cells.
BCAT1 knockdown-mediated suppression of melanoma cell proliferation and migration is associated with reduced oxidative phosphorylation.
Necroptosis pathway blockage attenuates PFKFB3 inhibitor-induced cell viability loss and genome instability in colorectal cancer cells.
P4HA1 as an unfavorable prognostic marker promotes cell migration and invasion of glioblastoma via inducing EMT process under hypoxia microenvironment.
Extracellular vesicles derived from M1 macrophages deliver miR-146a-5p and miR-146b-5p to suppress trophoblast migration and invasion by targeting TRAF6 in recurrent spontaneous abortion.
Epigenetically silenced linc00261 contributes to the metastasis of hepatocellular carcinoma via inducing the deficiency of FOXA2 transcription.
Long Non-Coding RNA CCAT2 Activates RAB14 and Acts as an Oncogene in Colorectal Cancer.
Honokiol Suppresses Perineural Invasion of Pancreatic Cancer by Inhibiting SMAD2/3 Signaling.
YBX1 Enhances Metastasis and Stemness by Transcriptionally Regulating MUC1 in Lung Adenocarcinoma.
Photobiomodulation With Blue Laser Inhibits Bladder Cancer Progression.
TRIM50 Suppresses Pancreatic Cancer Progression and Reverses the Epithelial-Mesenchymal Transition via Facilitating the Ubiquitous Degradation of Snail1.
PGK1 Is a Key Target for Anti-Glycolytic Therapy of Ovarian Cancer: Based on the Comprehensive Analysis of Glycolysis-Related Genes.
The lncRNA ADAMTS9-AS2 Regulates RPL22 to Modulate TNBC Progression via Controlling the TGF-β Signaling Pathway.
Cucurbitacin B Inhibits Cell Proliferation by Regulating X-Inactive Specific Transcript Expression in Tongue Cancer.
Chrysin Induced Cell Apoptosis Through H19/let-7a/COPB2 Axis in Gastric Cancer Cells and Inhibited Tumor Growth.
Long Non-Coding RNA LINC00467 Correlates to Poor Prognosis and Aggressiveness of Breast Cancer.
A Novel c-MET-Targeting Antibody-Drug Conjugate for Pancreatic Cancer.
Derivation and Validation of a Prognostic Model for Cancer Dependency Genes Based on CRISPR-Cas9 in Gastric Adenocarcinoma.
miR-139-5p Loss-Mediated WTAP Activation Contributes to Hepatocellular Carcinoma Progression by Promoting the Epithelial to Mesenchymal Transition.
Epigallocatechin-3-gallate inhibits proliferation and triggers apoptosis in colon cancer via the hedgehog/phosphoinositide 3-kinase pathways.
Aiduqing formula suppresses breast cancer metastasis via inhibiting CXCL1-mediated autophagy.
Homoharringtonine inhibits the progression of hepatocellular carcinoma by suppressing the PI3K/AKT/GSK3β/Slug signaling pathway.
Long non-coding RNA DUXAP9 promotes hepatocellular carcinoma cell stemness via directly interacting with sox9.
Demethylzeylasteral inhibits proliferation, migration, and invasion through FBXW7/c-Myc axis in gastric cancer.
CDC20 promotes bone formation via APC/C dependent ubiquitination and degradation of p65.
Identification of abnormally high expression of POGZ as a new biomarker associated with a poor prognosis in osteosarcoma.
The antioxidant N-acetylcysteine promotes immune response and inhibits epithelial-mesenchymal transition to alleviate pulmonary fibrosis in chronic obstructive pulmonary disease by suppressing the VWF/p38 MAPK axis.
PHLDA3 exerts an antitumor function in prostate cancer by down-regulating Wnt/β-catenin pathway via inhibition of Akt.
Reversible reprogramming of cardiomyocytes to a fetal state drives heart regeneration in mice.
KLK8 promotes the proliferation and metastasis of colorectal cancer via the activation of EMT associated with PAR1.
MiR-613 inhibits the proliferation, migration, and invasion of papillary thyroid carcinoma cells by directly targeting TAGLN2.
Circular RNA ZNF609 enhances proliferation and glycolysis during glioma progression by miR-378b/SLC2A1 axis.
TNFSF9 promotes metastasis of pancreatic cancer through Wnt/Snail signaling and M2 polarization of macrophages.
Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer.
Oleanolic acid inhibits the migration and invasion of hepatocellular carcinoma cells by promoting microRNA-122 expression.
MIER3 induces epithelial-mesenchymal transition and promotes breast cancer cell aggressiveness via forming a co-repressor complex with HDAC1/HDAC2/Snail.
Iguratimod decreases bleomycin-induced pulmonary fibrosis in association with inhibition of TNF-α in mice.
Effects of andrographolide on renal tubulointersticial injury and fibrosis. Evidence of its mechanism of action.
Generation of Urine-Derived Induced Pluripotent Stem Cell Line from Patients with Acute Kidney Injury.
Upregulation of microfibrillar-associated protein 2 is closely associated with tumor angiogenesis and poor prognosis in hepatocellular carcinoma.
Dihydroartemisinin suppresses proliferation, migration, the Wnt/β-catenin pathway and EMT via TNKS in gastric cancer.
Advanced Maternal Age-associated SIRT1 Deficiency Compromises Trophoblast Epithelial-Mesenchymal Transition through an Increase in Vimentin Acetylation.
Transcription factor POU4F2 promotes colorectal cancer cell migration and invasion through hedgehog-mediated epithelial-mesenchymal transition.
CDC42EP3 is a key promoter involved in the development and progression of gastric cancer.
PFP@PLGA/Cu(12)Sb(4)S(13)-mediated PTT ablates hepatocellular carcinoma by inhibiting the RAS/MAPK/MT-CO1 signaling pathway.
AnnexinA7 promotes epithelial-mesenchymal transition by interacting with Sorcin and contributes to aggressiveness in hepatocellular carcinoma.
UM-6 induces autophagy and apoptosis via the Hippo-YAP signaling pathway in cervical cancer.
ZEB1 represses biogenesis of circ-DOCK5 to facilitate metastasis in esophageal squamous cell carcinoma via a positive feedback loop with TGF-β.
Improved epithelial cell-cell adhesion using molecular mobility of supramolecular surfaces.
Identification of novel key genes associated with the metastasis of prostate cancer based on bioinformatics prediction and validation.
NOV/CCN3 Promotes Cell Migration and Invasion in Intrahepatic Cholangiocarcinoma via miR-92a-3p.
Upregulation of CPNE7 in mesenchymal stromal cells promotes oral squamous cell carcinoma metastasis through the NF-κB pathway.
MYH9 is crucial for stem cell-like properties in non-small cell lung cancer by activating mTOR signaling.
Overexpression of DTL enhances cell motility and promotes tumor metastasis in cervical adenocarcinoma by inducing RAC1-JNK-FOXO1 axis.
NOTCH2NLA silencing inhibits ovarian carcinoma progression and oncogenic activity in vivo and in vitro.
Hsa_circ_0001326 regulates proliferation, migration, invasion, and EMT of HTR-8/SVneo cells via increasing IL16 expression.
P-element Induced WImpy protein-like RNA-mediated gene silencing 2 regulates tumor cell progression, apoptosis, and metastasis in oral squamous cell carcinoma.
Abnormally elevated ubiquilin‑1 expression in breast cancer regulates metastasis and stemness via AKT signaling.
Silencing ACTG1 Expression Induces Prostate Cancer Epithelial Mesenchymal Transition Through MAPK/ERK Signaling Pathway.
SC66 inhibits the proliferation and induces apoptosis of human bladder cancer cells by targeting the AKT/β-catenin pathway.
O-GlcNAcylation promotes the migratory ability of hepatocellular carcinoma cells via regulating FOXA2 stability and transcriptional activity.
Blood glucose control contributes to protein stability of Ski-related novel protein N in a rat model of diabetes.
Tspan5 promotes epithelial-mesenchymal transition and tumour metastasis of hepatocellular carcinoma by activating Notch signalling.
HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma.
Si-Wu-Tang ameliorates fibrotic liver injury via modulating intestinal microbiota and bile acid homeostasis.
Fisetin inhibits the proliferation, migration and invasion of pancreatic cancer by targeting PI3K/AKT/mTOR signaling.
miR-30b-5p inhibits proliferation, invasion, and migration of papillary thyroid cancer by targeting GALNT7 via the EGFR/PI3K/AKT pathway.
HMMR is a downstream target of FOXM1 in enhancing proliferation and partial epithelial-to-mesenchymal transition of bladder cancer cells.
Drug-containing serum of rhubarb-astragalus capsule inhibits the epithelial-mesenchymal transformation of HK-2 by downregulating TGF-β1/p38MAPK/Smad2/3 pathway.
Single-Cell Analyses Reveal Mechanisms of Cancer Stem Cell Maintenance and Epithelial-Mesenchymal Transition in Recurrent Bladder Cancer.
Deletion of miR-15a inhibited glioma development via targeting Smad7 and inhibiting EMT pathway.
AICAR enhances the cytotoxicity of PFKFB3 inhibitor in an AMPK signaling-independent manner in colorectal cancer cells.
SAA1 is transcriptionally activated by STAT3 and accelerates renal interstitial fibrosis by inducing endoplasmic reticulum stress.
Long non‑coding RNA MIR4713HG aggravates malignant behaviors in oral tongue squamous cell carcinoma via binding with microRNA let‑7c‑5p.
miR-509-3p Suppresses Migration, Invasion, and Epithelial- Mesenchymal Transition in Melanoma Cells by Targeting Collagen Triple Helix Repeat Containing 1.
Stress-induced phosphoprotein 1 facilitates breast cancer cell progression and indicates poor prognosis for breast cancer patients.
Exosomal microRNA-301a-3p promotes the proliferation and invasion of nasopharyngeal carcinoma cells by targeting BTG1 mRNA.
The clinical significance, prognostic value and biological role of lncRNA LINC01793 in oral squamous cell carcinoma.
Tubule-specific protein nanocages potentiate targeted renal fibrosis therapy.
Ginsenoside CK Inhibits Hypoxia-Induced Epithelial-Mesenchymal Transformation through the HIF-1α/NF-κB Feedback Pathway in Hepatocellular Carcinoma.
STIP1 knockdown suppresses colorectal cancer cell proliferation, migration and invasion by inhibiting STAT3 pathway.
The miR-378c-Samd1 circuit promotes phenotypic modulation of vascular smooth muscle cells and foam cells formation in atherosclerosis lesions.
Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice.
A HIF1A/miR-485-5p/SRPK1 axis modulates the aggressiveness of glioma cells upon hypoxia.
Trim47 overexpression correlates with poor prognosis in gastric cancer.
Moderate oxidative stress promotes epithelial-mesenchymal transition in the lens epithelial cells via the TGF-β/Smad and Wnt/β-catenin pathways.
Abnormal cGMP-dependent protein kinase I-mediated decidualization in preeclampsia.
MiR-520a-3p inhibits malignant progression of epithelial ovarian cancer by targeting SUV39H1 expression.
Aptamer-SH2 superbinder-based targeted therapy for pancreatic ductal adenocarcinoma.
HN1 promotes tumor growth and metastasis of anaplastic thyroid carcinoma by interacting with STMN1.
A 2-Benzylmalonate Derivative as STAT3 Inhibitor Suppresses Tumor Growth in Hepatocellular Carcinoma by Upregulating β-TrCP E3 Ubiquitin Ligase.
Sesquiterpene Lactone Deoxyelephantopin Isolated from Elephantopus scaber and Its Derivative DETD-35 Suppress BRAF(V600E) Mutant Melanoma Lung Metastasis in Mice.
Anti-Fibrosis Effects of Magnesium Lithospermate B in Experimental Pulmonary Fibrosis: By Inhibiting TGF-βRI/Smad Signaling.
The MIR155 host gene/microRNA-627/HMGB1/NF-κB loop modulates fibroblast proliferation and extracellular matrix deposition.
Upregulation of bromodomain PHD finger transcription factor in ovarian cancer and its critical role for cancer cell proliferation and survival.
Suberoylanilide Hydroxamic Acid (SAHA) Reduces Fibrosis Markers and Deactivates Human Stellate Cells via the Epithelial-Mesenchymal Transition (EMT).
Runx2 deficiency in junctional epithelium of mouse molars decreases the expressions of E-cadherin and junctional adhesion molecule 1.
Long non‑coding RNA MIR4435‑2HG promotes the progression of head and neck squamous cell carcinoma by regulating the miR‑383‑5p/RBM3 axis.
Effects of CDKN2B-AS1 on cellular proliferation, invasion and AKT3 expression are attenuated by miR-424-5p in a model of ovarian endometriosis.
Fructose-1,6-bisphosphatase aggravates oxidative stress-induced apoptosis in asthma by suppressing the Nrf2 pathway.
SEC61G is upregulated and required for tumor progression in human kidney cancer.
MicroRNA-133a-3p suppresses malignant behavior of non-small cell lung cancer cells by negatively regulating ERBB2.
LEM domain containing 1 promotes thyroid cancer cell proliferation and migration by activating the Wnt/β-catenin signaling pathway and epithelial-mesenchymal transition.
Downregulation of ARMC8 promotes tumorigenesis through activating Wnt/β-catenin pathway and EMT in cutaneous squamous cell carcinomas.
YWHAE as an HE4 interacting protein can influence the malignant behaviour of ovarian cancer by regulating the PI3K/AKT and MAPK pathways.
LncRNA Bmp1 promotes the healing of intestinal mucosal lesions via the miR-128-3p/PHF6/PI3K/AKT pathway.
NLRP3 induces the autocrine secretion of IL-1β to promote epithelial-mesenchymal transition and metastasis in breast cancer.
LncRNA MONC suppresses the malignant phenotype of Endometrial Cancer Stem Cells and Endometrial Carcinoma Cells by regulating the MiR-636/GLCE axis.
STAT3/HIF-1α signaling activation mediates peritoneal fibrosis induced by high glucose.
MicroRNA-139 inhibits pancreatic-cancer carcinogenesis by suppressing RalB via the Ral/RAC/PI3K pathway.
Small extracellular ring domain is necessary for CD82/KAI1'anti-metastasis function.
Identification of a Novel TAR RNA-Binding Protein 2 Modulator with Potential Therapeutic Activity against Hepatocellular Carcinoma.
VEGF/Src signaling mediated pleural barrier damage and increased permeability contributes to subpleural pulmonary fibrosis.
Neutrophil extracellular traps promote gastric cancer metastasis by inducing epithelial‑mesenchymal transition.
MDM2 induces EMT via the B‑Raf signaling pathway through 14‑3‑3.
CXCL6 fuels the growth and metastases of esophageal squamous cell carcinoma cells both in vitro and in vivo through upregulation of PD-L1 via activation of STAT3 pathway.
Regulatory effect of microRNA-223-3p on breast cancer cell processes via the Hippo/Yap signaling pathway.
miR-665 inhibits epithelial-to-mesenchymal transition in bladder cancer via the SMAD3/SNAIL axis.
LncRNA SGMS1-AS1 regulates lung adenocarcinoma cell proliferation, migration, invasion, and EMT progression via miR-106a-5p/MYLI9 axis.
The oncogenic role of the cerebral endothelial cell adhesion molecule (CERCAM) in bladder cancer cells in vitro and in vivo.
CHN1 promotes epithelial-mesenchymal transition via the Akt/GSK-3β/Snail pathway in cervical carcinoma.
A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein.
LRRC19 Promotes Permeability of the Gut Epithelial Barrier Through Degrading PKC-ζ and PKCι/λ to Reduce Expression of ZO1, ZO3, and Occludin.
A mesenchymal-like subpopulation in non-neuroendocrine SCLC contributes to metastasis.
Circular RNA circ_001422 promotes the progression and metastasis of osteosarcoma via the miR-195-5p/FGF2/PI3K/Akt axis.
LncRNA PCGEM1 induces proliferation and migration in non-small cell lung cancer cells through modulating the miR-590-3p/SOX11 axis.
Mitochondrial creatine kinase 1 in non-small cell lung cancer progression and hypoxia adaptation.
Fangchinoline exerts antitumour activity by suppressing the EGFR‑PI3K/AKT signalling pathway in colon adenocarcinoma.
MSH6 Aggravates the Hypoxic Microenvironment via Regulating HIF1A to Promote the Metastasis of Glioblastoma Multiforme.
Long noncoding RNA EPB41L4A-AS1 functions as an oncogene by regulating the Rho/ROCK pathway in colorectal cancer.
Laminin‑332 mediates proliferation, apoptosis, invasion, migration and epithelial‑to‑mesenchymal transition in pancreatic ductal adenocarcinoma.
CD147 deficiency in T cells prevents thymic involution by inhibiting the EMT process in TECs in the presence of TGFβ.
Triptolidenol, isolated from Tripterygium wilfordii, disrupted NF-κB/COX-2 pathway by targeting ATP-binding sites of IKKβ in clear cell renal cell carcinoma.
Lidocaine inhibits the metastatic potential of ovarian cancer by blocking Na(V) 1.5-mediated EMT and FAK/Paxillin signaling pathway.
Triple co-culture and perfusion bioreactor for studying the interaction between Neisseria gonorrhoeae and neutrophils: A novel 3D tissue model for bacterial infection and immunity.
Obacunone Attenuates Liver Fibrosis with Enhancing Anti-Oxidant Effects of GPx-4 and Inhibition of EMT.
The long intergenic noncoding RNA GAS5 reduces cisplatin-resistance in non-small cell lung cancer through the miR-217/LHPP axis.
miR-335-5p suppresses gastric cancer progression by targeting MAPK10.
Overexpression of NCAPG inhibits cardia adenocarcinoma apoptosis and promotes epithelial-mesenchymal transition through the Wnt/β-catenin signaling pathway.
Circ_0001438 participates in the pathogenesis of preeclampsia via the circ_0001438/miR-942/NLRP3 regulatory network.
A "dual-guide" bioinspired drug delivery strategy of a macrophage-based carrier against postoperative triple-negative breast cancer recurrence.
Berberine inhibits intestinal epithelial barrier dysfunction in colon caused by peritoneal dialysis fluid by improving cell migration.
Tumor-associated macrophages promote pancreatic ductal adenocarcinoma progression by inducing epithelial-to-mesenchymal transition.
PGRN(-/-) TAMs-derived exosomes inhibit breast cancer cell invasion and migration and its mechanism exploration.
SLC6A8 is involved in the progression of non-small cell lung cancer through the Notch signaling pathway.
The interaction between lipocalin 2 and dipyridine ketone hydrazone dithiocarbamte may influence respective function in proliferation and metastasis-related gene expressions in HepG2 cell.
Piezo type mechanosensitive ion channel component 1 facilitates gastric cancer omentum metastasis.
M2 macrophage-derived G-CSF promotes trophoblasts EMT, invasion and migration via activating PI3K/Akt/Erk1/2 pathway to mediate normal pregnancy.
Involvement of miR-27a-3p in diabetic nephropathy via affecting renal fibrosis, mitochondrial dysfunction, and endoplasmic reticulum stress.
USP1-WDR48 deubiquitinase complex enhances TGF-β induced epithelial-mesenchymal transition of TNBC cells via stabilizing TAK1.
Triptolide inhibits epithelial-mesenchymal transition phenotype through the p70S6k/GSK3/β-catenin signaling pathway in taxol-resistant human lung adenocarcinoma.
Transcription of MRPL12 regulated by Nrf2 contributes to the mitochondrial dysfunction in diabetic kidney disease.
Role of SIK1 in the transition of acute kidney injury into chronic kidney disease.
RECQL4 regulates DNA damage response and redox homeostasis in esophageal cancer.
DUOX2 promotes the progression of colorectal cancer cells by regulating the AKT pathway and interacting with RPL3.
GABARAP suppresses EMT and breast cancer progression via the AKT/mTOR signaling pathway.
High expression of vinculin predicts poor prognosis and distant metastasis and associates with influencing tumor-associated NK cell infiltration and epithelial-mesenchymal transition in gastric cancer.
Compound Kushen Injection intervenes metabolic reprogramming and epithelial-mesenchymal transition of HCC via regulating β-catenin/c-Myc signaling.
Long non-coding RNA AC122108.1 promotes lung adenocarcinoma brain metastasis and progression through the Wnt/β-catenin pathway by directly binding to aldolase A.
PDGF-BB promotes vascular smooth muscle cell migration by enhancing Pim-1 expression via inhibiting miR-214.
IFIT1 modulates the proliferation, migration and invasion of pancreatic cancer cells via Wnt/β-catenin signaling.
Evaluation of autofluorescence visualization system in the delineation of oral squamous cell carcinoma surgical margins.
BAIAP2L2 promotes the proliferation, migration and invasion of osteosarcoma associated with the Wnt/β-catenin pathway.
Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial-mesenchymal plasticity of human peritoneal mesothelial cells.
TRIP4 transcriptionally activates DDIT4 and subsequent mTOR signaling to promote glioma progression.
Hsa_circ_0030586 promotes epithelial-mesenchymal transition in prostate cancer via PI3K-AKT signaling.
Circular RNA CNOT2 knockdown regulates twist family BHLH transcription factor via targeting microRNA 409-3p to prevent breast cancer invasion, migration and epithelial-mesenchymal transition.
Long non-coding RNA VCAN-AS1 promotes the malignant behaviors of breast cancer by regulating the miR-106a-5p-mediated STAT3/HIF-1α pathway.
Knockdown of carbohydrate sulfotransferase 12 decreases the proliferation and mobility of glioblastoma cells via the WNT/β-catenin pathway.
SETD8 induces stemness and epithelial-mesenchymal transition of pancreatic cancer cells by regulating ROR1 expression.
Long non-coding RNA CRNDE exacerbates NPC advancement mediated by the miR-545-5p/CCND2 axis.
USP3 promotes gastric cancer progression and metastasis by deubiquitination-dependent COL9A3/COL6A5 stabilisation.
Identification of key genes as predictive biomarkers for osteosarcoma metastasis using translational bioinformatics.
TMED3 exerts a protumor function in non-small cell lung cancer by enhancing the Wnt/β-catenin pathway via regulation of AKT.
MiR-26b-5p inhibits cell proliferation and EMT by targeting MYCBP in triple-negative breast cancer.
The miR-223-3p/MAP1B axis aggravates TGF-β-induced proliferation and migration of BPH-1 cells.
ATF3 inhibits arsenic-induced malignant transformation of human bronchial epithelial cells by attenuating inflammation.
TMEM229A suppresses non‑small cell lung cancer progression via inactivating the ERK pathway.
Chromium (VI) promotes EMT by regulating FLNA in BLCA.
W436, a novel SMART derivative, exhibits anti-hepatocarcinoma activity by inducing apoptosis and G2/M cell cycle arrest in vitro and in vivo and induces protective autophagy.
miR‑200b upregulation promotes migration of BEAS‑2B cells following long‑term exposure to cigarette smoke by targeting ETS1.
Tripterygium glycoside suppresses epithelial‑to‑mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway.
Melatonin inhibits gallbladder cancer cell migration and invasion via ERK-mediated induction of epithelial-to-mesenchymal transition.
Depletion of CIP2A inhibits the proliferation, migration, invasion and epithelial-mesenchymal transition of glioma cells.
Caveolin-1 facilitates cell migration by upregulating nuclear receptor 4A2/retinoid X receptor α-mediated β-galactoside α2,6-sialyltransferase I expression in human hepatocarcinoma cells.
MD2 blockage prevents the migration and invasion of hepatocellular carcinoma cells via inhibition of the EGFR signaling pathway.
Association of CASC18/miR-20a-3p/TGFB2 ceRNA axis with occult lymph node metastasis in tongue squamous cell carcinoma.
Cyanidin-3-glucoside suppresses the progression of lung adenocarcinoma by downregulating TP53I3 and inhibiting PI3K/AKT/mTOR pathway.
IL-1β augments TGF-β inducing epithelial-mesenchymal transition of epithelial cells and associates with poor pulmonary function improvement in neutrophilic asthmatics.
Low-Intensity Extracorporeal Shock Wave Therapy Promotes Bladder Regeneration and Improves Overactive Bladder Induced by Ovarian Hormone Deficiency from Rat Animal Model to Human Clinical Trial.
Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.
2-Hydroxypropyl-β-cyclodextrin Regulates the Epithelial to Mesenchymal Transition in Breast Cancer Cells by Modulating Cholesterol Homeostasis and Endoplasmic Reticulum Stress.
Macrophage polarization-associated lnc-Ma301 interacts with caprin-1 to inhibit hepatocellular carcinoma metastasis through the Akt/Erk1 pathway.
Rab1A promotes cell proliferation and migration by upregulating Gli1 in colorectal cancer.
Colorectal Cancer Stem Cell States Uncovered by Simultaneous Single-Cell Analysis of Transcriptome and Telomeres.
CRSP8 promotes thyroid cancer progression by antagonizing IKKα-induced cell differentiation.
Fusobacterium nucleatum Promotes Cisplatin-Resistance and Migration of Oral Squamous Carcinoma Cells by Up-Regulating Wnt5a-Mediated NFATc3 Expression.
The miR-136-5p/ROCK1 axis suppresses invasion and migration, and enhances cisplatin sensitivity in head and neck cancer cells.
SPT6 recruits SND1 to co-activate human telomerase reverse transcriptase to promote colon cancer progression.
H. sinensis mycelium inhibits epithelial-mesenchymal transition by inactivating the midkine pathway in pulmonary fibrosis.
Abnormal spindle-like microcephaly-associated protein enhances cell invasion through Wnt/β-catenin-dependent regulation of epithelial-mesenchymal transition in non-small cell lung cancer cells.
Effects of miR-132-3p on progress and epithelial mesenchymal transition of non-small cell lung cancer via regulating KLF7.
FZD2 promotes TGF-β-induced epithelial-to-mesenchymal transition in breast cancer via activating notch signaling pathway.
Screening and identification of haptoglobin showing its important role in pathophysiological process of gallbladder carcinoma.
Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer.
ADAMTS19 Suppresses Cell Migration and Invasion by Targeting S100A16 via the NF-κB Pathway in Human Gastric Cancer.
Inhibition of growth and metastasis of breast cancer by targeted delivery of 17-hydroxy-jolkinolide B via hyaluronic acid-coated liposomes.
TET1 may contribute to hypoxia-induced epithelial to mesenchymal transition of endometrial epithelial cells in endometriosis.
Histone Deacetylases Inhibit the Snail2-Mediated EMT During Metastasis of Hepatocellular Carcinoma Cells.
Hypoxia-Inducible Ubiquitin Specific Peptidase 13 Contributes to Tumor Growth and Metastasis via Enhancing the Toll-Like Receptor 4/Myeloid Differentiation Primary Response Gene 88/Nuclear Factor-κB Pathway in Hepatocellular Carcinoma.
A Novel Van der Woude Syndrome-Causing IRF6 Variant Is Subject to Incomplete Non-sense-Mediated mRNA Decay Affecting the Phenotype of Keratinocytes.
miR-193a-3p Mediates Placenta Accreta Spectrum Development by Targeting EFNB2 via Epithelial-Mesenchymal Transition Pathway Under Decidua Defect Conditions.
Keratin 17 Suppresses Cell Proliferation and Epithelial-Mesenchymal Transition in Pancreatic Cancer.
miR-124-3p Suppresses the Invasiveness and Metastasis of Hepatocarcinoma Cells via Targeting CRKL.
PKM2 Promotes Breast Cancer Progression by Regulating Epithelial Mesenchymal Transition.
Anticancer Activity of Modified Tongyou Decoction on Eca109 Esophageal Cancer Cell Invasion and Metastasis through Regulation of the Epithelial-Mesenchymal Transition Mediated by the HIF-1α-Snail Axis.
GDF15 Repression Contributes to 5-Fluorouracil Resistance in Human Colon Cancer by Regulating Epithelial-Mesenchymal Transition and Apoptosis.
miR-876 Inhibits EMT and Liver Fibrosis via POSTN to Suppress Metastasis in Hepatocellular Carcinoma.
The Significance of Circular RNA DDX17 in Prostate Cancer.
BTG1 inhibits malignancy as a novel prognosis signature in endometrial carcinoma.
Down-regulation of TRIB3 inhibits the progression of ovarian cancer via MEK/ERK signaling pathway.
miR-454 suppresses the proliferation and invasion of ovarian cancer by targeting E2F6.
HBx mediated Increase of SIRT1 Contributes to HBV-related Hepatocellular Carcinoma Tumorigenesis.
Cdh1 functions as an oncogene by inducing self-renewal of lung cancer stem-like cells via oncogenic pathways.
Lin28A Regulates Stem-like Properties of Ovarian Cancer Cells by Enriching RAN and HSBP1 mRNA and Up-regulating its Protein Expression.
S100A6 promotes proliferation and migration of HepG2 cells via increased ubiquitin-dependent degradation of p53.
Paeoniflorin Alleviates Abnormalities in Rats with Functional Dyspepsia by Stimulating the Release of Acetylcholine.
Treatment with a PPAR-γ Agonist Protects Against Hyperuricemic Nephropathy in a Rat Model.
miR-370-3p Alleviates Ulcerative Colitis-Related Colorectal Cancer in Mice Through Inhibiting the Inflammatory Response and Epithelial-Mesenchymal Transition.
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
The role of Stim1 in the progression of lupus nephritis in mice.
MicroRNA 885-5p Inhibits Hepatocellular Carcinoma Metastasis by Repressing AEG1.
MicroRNA-623 Inhibits Epithelial-Mesenchymal Transition to Attenuate Glioma Proliferation by Targeting TRIM44.
Characterization of Triple-Negative Breast Cancer MDA-MB-231 Cell Spheroid Model.
Low-Dose Radiation Promotes Invasion and Migration of A549 Cells by Activating the CXCL1/NF-κB Signaling Pathway.
Dihydroartemisinin Prevents Progression and Metastasis of Head and Neck Squamous Cell Carcinoma by Inhibiting Polarization of Macrophages in Tumor Microenvironment.
Rap2c as a Novel Biomarker for Predicting Poor Prognosis in Glioma.
Long Non-Coding RNA SPRY4-IT1 Reverses Cisplatin Resistance by Downregulating MPZL-1 via Suppressing EMT in NSCLC.
Fibroblast Activation Protein (FAP) Overexpression Induces Epithelial-Mesenchymal Transition (EMT) in Oral Squamous Cell Carcinoma by Down-Regulating Dipeptidyl Peptidase 9 (DPP9).
Tumor Suppressor microRNA-138 Suppresses Low-Grade Glioma Development and Metastasis via Regulating IGF2BP2.
TIM-3 Participates in the Invasion and Metastasis of Nasopharyngeal Carcinoma via SMAD7/SMAD2/SNAIL1 Axis-Mediated Epithelial-Mesenchymal Transition.
Empagliflozin Protects Against Proximal Renal Tubular Cell Injury Induced by High Glucose via Regulation of Hypoxia-Inducible Factor 1-Alpha.
Profiling and Integrated Analysis of Differentially Expressed Circular RNAs in Plasma Exosomes as Novel Biomarkers for Advanced-Stage Lung Adenocarcinoma.
MST4 Regulates Epithelial-Mesenchymal Transition of Choriocarcinoma by Mediating TGF-β1 Expression.
Simultaneous Inhibition of Ornithine Decarboxylase 1 and Pyruvate Kinase M2 Exerts Synergistic Effects Against Hepatocellular Carcinoma Cells.
Prognostic Significance and Related Mechanisms of Hexokinase 1 in Ovarian Cancer.
CircHIPK3 Promotes Gemcitabine (GEM) Resistance in Pancreatic Cancer Cells by Sponging miR-330-5p and Targets RASSF1.
Downregulation of Immortalization-Upregulated Protein Suppresses the Progression of Breast Cancer Cell Lines by Regulating Epithelial-Mesenchymal Transition.
Blocking circ_0000520 Suppressed Breast Cancer Cell Growth, Migration and Invasion Partially via miR-1296/SP1 Axis Both in vitro and in vivo.
Blocking circ_0013912 Suppressed Cell Growth, Migration and Invasion of Pancreatic Ductal Adenocarcinoma Cells in vitro and in vivo Partially Through Sponging miR-7-5p.
LINC00963 Promotes Ovarian Cancer Proliferation, Migration and EMT via the miR-378g /CHI3L1 Axis.
KLHL22 Regulates the EMT and Proliferation in Colorectal Cancer Cells in Part via the Wnt/β-Catenin Signaling Pathway.
CUB Domain-Containing Protein-1 Promotes Proliferation, Migration and Invasion in Cervical Cancer Cells.
NUDT21 Suppresses Breast Cancer Tumorigenesis Through Regulating CPSF6 Expression.
METTL14 Inhibits Hepatocellular Carcinoma Metastasis Through Regulating EGFR/PI3K/AKT Signaling Pathway in an m6A-Dependent Manner.
Circadian Clock Protein PERIOD2 Suppresses the PI3K/Akt Pathway and Promotes Cisplatin Sensitivity in Ovarian Cancer.
Cytokine TNF-α promotes invasion and metastasis of gastric cancer by down-regulating Pentraxin3.
TRIM67 Promotes the Proliferation, Migration, and Invasion of Non-Small-Cell Lung Cancer by Positively Regulating the Notch Pathway.
Biological implications of PTEN upregulation and altered sodium/iodide symporter intracellular distribution in resveratrol-suppressed anaplastic thyroid cancer cells.
Total saponins from Lilium lancifolium: a promising alternative to inhibit the growth of gastric carcinoma cells.
TNFAIP8 promotes the migration of clear cell renal cell carcinoma by regulating the EMT.
P4HA2 contributes to cervical cancer progression via inducing epithelial-mesenchymal transition.
Vitamin C Inhibits Metastasis of Peritoneal Tumors By Preventing Spheroid Formation in ID8 Murine Epithelial Peritoneal Cancer Model.
Sanguisorba officinalis L. Suppresses Triple-Negative Breast Cancer Metastasis by Inhibiting Late-Phase Autophagy via Hif-1α/Caveolin-1 Signaling.
Hyperoside Attenuates Bleomycin-Induced Pulmonary Fibrosis Development in Mice.
Trimetazidine Inhibits Renal Tubular Epithelial Cells to Mesenchymal Transition in Diabetic Rats via Upregulation of Sirt1.
GADD45B Promotes Glucose-Induced Renal Tubular Epithelial-Mesenchymal Transition and Apoptosis via the p38 MAPK and JNK Signaling Pathways.
SMYD2 suppresses APC2 expression to activate the Wnt/β-catenin pathway and promotes epithelial-mesenchymal transition in colorectal cancer.
Non-canonical signaling pathway of SNAI2 induces EMT in ovarian cancer cells by suppressing miR-222-3p transcription and upregulating PDCD10.
BYSL Promotes Glioblastoma Cell Migration, Invasion, and Mesenchymal Transition Through the GSK-3β/β-Catenin Signaling Pathway.
Folliculin Controls the Intracellular Survival and Trans-Epithelial Passage of Neisseria gonorrhoeae.
Regulation of Integrin Subunit Alpha 2 by miR-135b-5p Modulates Chemoresistance in Gastric Cancer.
Tumor mutation burden and JARID2 gene alteration are associated with short disease-free survival in locally advanced triple-negative breast cancer.
Xanthan gum and locust bean gum substrate improves bovine embryo development.
Shikonin blocks human lung adenocarcinoma cell migration and invasion in the inflammatory microenvironment via the IL‑6/STAT3 signaling pathway.
RUNX3-dependent oxidative epithelial-to-mesenchymal transition in methamphetamine-induced chronic lung injury.
Long non-coding RNA MALAT1 targeting STING transcription promotes bronchopulmonary dysplasia through regulation of CREB.
AKR1C2 acts as a targetable oncogene in esophageal squamous cell carcinoma via activating PI3K/AKT signaling pathway.
Circular RNA hsa_circ_0005556 Accelerates Gastric Cancer Progression by Sponging miR-4270 to Increase MMP19 Expression.
Polyphyllin II inhibits human bladder cancer migration and invasion by regulating EMT-associated factors and MMPs.
PAK6 promotes cervical cancer progression through activation of the Wnt/β-catenin signaling pathway.
BAIAP2L2 promotes the progression of gastric cancer via AKT/mTOR and Wnt3a/β-catenin signaling pathways.
Novel long non-coding RNA LINC02323 promotes epithelial-mesenchymal transition and metastasis via sponging miR-1343-3p in lung adenocarcinoma.
The F-box protein FBXO11 restrains hepatocellular carcinoma stemness via promotion of ubiquitin-mediated degradation of Snail.
Circular RNA circREPS2 Acts as a Sponge of miR-558 to Suppress Gastric Cancer Progression by Regulating RUNX3/β-catenin Signaling.
Porphyromonas gingivalis disrupts vascular endothelial homeostasis in a TLR-NF-κB axis dependent manner.
2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol (SQ) inhibits cancer cell metastasis behavior of TNBC via suppressing EMT and VEGF.
miR-7 Reduces Breast Cancer Stem Cell Metastasis via Inhibiting RELA to Decrease ESAM Expression.
LncRNA Mical2/miR-203a-3p sponge participates in epithelial-mesenchymal transition by targeting p66Shc in liver fibrosis.
Chronic stress promotes EMT-mediated metastasis through activation of STAT3 signaling pathway by miR-337-3p in breast cancer.
MEST promotes bladder cancer cell proliferation, migration and invasion via STAT3/Twist-1-mediated EMT.
Paris polyphylla ethanol extract induces G2/M arrest and suppresses migration and invasion in bladder cancer.
MYCT1 inhibits the EMT and migration of laryngeal cancer cells via the SP1/miR-629-3p/ESRP2 pathway.
Blocking NFATc3 ameliorates azoxymethane/dextran sulfate sodium induced colitis-associated colorectal cancer in mice via the inhibition of inflammatory responses and epithelial-mesenchymal transition.
Elevated Expression of RIOK1 Is Correlated with Breast Cancer Hormone Receptor Status and Promotes Cancer Progression.
IL-6 induces tumor suppressor protein tyrosine phosphatase receptor type D by inhibiting miR-34a to prevent IL-6 signaling overactivation.
SUMOylation of HSP27 regulates PKM2 to promote esophageal squamous cell carcinoma progression.
Deubiquitinase USP29 promotes gastric cancer cell migration by cooperating with phosphatase SCP1 to stabilize Snail protein.
Melatonin synergizes BRAF-targeting agent dabrafenib for the treatment of anaplastic thyroid cancer by inhibiting AKT/hTERT signalling.
Emodin inhibiting neutrophil elastase-induced epithelial-mesenchymal transition through Notch1 signalling in alveolar epithelial cells.
The PI3Kα inhibitor DFX24 suppresses tumor growth and metastasis in non-small cell lung cancer via ERK inhibition and EPHB6 reactivation.
APE1 promotes proliferation and migration of cutaneous squamous cell carcinoma.
Calreticulin promotes EMT in pancreatic cancer via mediating Ca(2+) dependent acute and chronic endoplasmic reticulum stress.
YTHDF2 mediates the mRNA degradation of the tumor suppressors to induce AKT phosphorylation in N6-methyladenosine-dependent way in prostate cancer.
MicroRNA-200b/c-3p regulate epithelial plasticity and inhibit cutaneous wound healing by modulating TGF-β-mediated RAC1 signaling.
Circular RNA circ_PVT1 induces epithelial-mesenchymal transition to promote metastasis of cervical cancer.
CUEDC1 inhibits epithelial-mesenchymal transition via the TβRI/Smad signaling pathway and suppresses tumor progression in non-small cell lung cancer.
GATA6 promotes epithelial-mesenchymal transition and metastasis through MUC1/β-catenin pathway in cholangiocarcinoma.
miR-15a-5p suppresses peritoneal fibrosis induced by peritoneal dialysis via targeting VEGF in rats.
Polydatin inhibits ZEB1-invoked epithelial-mesenchymal transition in fructose-induced liver fibrosis.
MSCs reduce airway remodeling in the lungs of asthmatic rats through the Wnt/β-catenin signaling pathway.
Long noncoding RNA SNHG12 modulated by human papillomavirus 16 E6/E7 promotes cervical cancer progression via ERK/Slug pathway.
SUMO4 small interfering RNA attenuates invasion and migration via the JAK2/STAT3 pathway in non-small cell lung cancer cells.
DEPDC1B promotes migration and invasion in pancreatic ductal adenocarcinoma by activating the Akt/GSK3β/Snail pathway.
SNHG1 promotes proliferation, migration and invasion of bladder cancer cells via the PI3K/AKT signaling pathway.
Wnt/β-Catenin Signaling Axis Is Required for TFEB-Mediated Gastric Cancer Metastasis and Epithelial-Mesenchymal Transition.
Anthocyanins from Aronia melanocarpa Induce Apoptosis in Caco-2 Cells through Wnt/β-Catenin Signaling Pathway.
AGEs-RAGE axis causes endothelial-to-mesenchymal transition in early calcific aortic valve disease via TGF-β1 and BMPR2 signaling.
OXPHOS-dependent metabolic reprogramming prompts metastatic potential of breast cancer cells under osteogenic differentiation.
Deficiency of pseudogene UPAT leads to hepatocellular carcinoma progression and forms a positive feedback loop with ZEB1.
Exosome-derived ENO1 regulates integrin α6β4 expression and promotes hepatocellular carcinoma growth and metastasis.
Serum KIAA1199 is an advanced-stage prognostic biomarker and metastatic oncogene in cholangiocarcinoma.
Sirtuin 6 attenuates epithelial-mesenchymal transition by suppressing the TGF-β1/Smad3 pathway and c-Jun in asthma models.
FGD1 exhibits oncogenic properties in hepatocellular carcinoma through regulating cell morphology, autophagy and mitochondrial function.
BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.
The roles of dipeptidyl peptidase-4 and its inhibitors in the regulation of airway epithelial-mesenchymal transition.
PHLDA2 regulates EMT and autophagy in colorectal cancer via the PI3K/AKT signaling pathway.
IMPDH1/YB-1 Positive Feedback Loop Assembles Cytoophidia and Represents a Therapeutic Target in Metastatic Tumors.
Downregulation of GLYR1 contributes to microsatellite instability colorectal cancer by targeting p21 via the p38MAPK and PI3K/AKT pathways.
MAY, a novel tubulin inhibitor, induces cell apoptosis in A549 and A549/Taxol cells and inhibits epithelial-mesenchymal transition in A549/Taxol cells.
Bioinformatic analysis reveals the importance of epithelial-mesenchymal transition in the development of endometriosis.
MS-275 combined with cisplatin exerts synergistic antitumor effects in human esophageal squamous cell carcinoma cells.
A dual receptors-targeting and size-switchable "cluster bomb" co-loading chemotherapeutic and transient receptor potential ankyrin 1 (TRPA-1) inhibitor for treatment of triple negative breast cancer.
MiR-328-3p inhibits cell proliferation and metastasis in colorectal cancer by targeting Girdin and inhibiting the PI3K/Akt signaling pathway.
An Amino Acid-Based Oral Rehydration Solution Regulates Radiation-Induced Intestinal Barrier Disruption in Mice.
PLEK2 mediates metastasis and vascular invasion via the ubiquitin-dependent degradation of SHIP2 in non-small cell lung cancer.
Downregulated placental expression of linc00468 contributes to trophoblast dysfunction by inducing epithelial-mesenchymal transition.
The Mutational Features of Aristolochic Acid-Induced Mouse and Human Liver Cancers.
Rosmarinic acid exerts an anticancer effect on osteosarcoma cells by inhibiting DJ-1 via regulation of the PTEN-PI3K-Akt signaling pathway.
Resveratrol protects the integrity of alveolar epithelial barrier via SIRT1/PTEN/p-Akt pathway in methamphetamine-induced chronic lung injury.
LncRNA PTCSC3 inhibits the proliferation, invasion and migration of cervical cancer cells via sponging miR-574-5p.
Linc00261 inhibits metastasis and the WNT signaling pathway of pancreatic cancer by regulating a miR‑552‑5p/FOXO3 axis.
Interleukin 1β/1RA axis in colorectal cancer regulates tumor invasion, proliferation and apoptosis via autophagy.
Cyclovirobuxine D Exerts Anticancer Effects by Suppressing the EGFR-FAK-AKT/ERK1/2-Slug Signaling Pathway in Human Hepatocellular Carcinoma.
microRNA-141 inhibits TGF-β1-induced epithelial-to-mesenchymal transition through inhibition of the TGF-β1/SMAD2 signalling pathway in endometriosis.
LncRNA MALAT1 knockdown inhibits cell migration and invasion by suppressing autophagy through miR-384/GOLM1 axis in glioma.
Decreasing New York esophageal squamous cell carcinoma 1 expression inhibits multiple myeloma growth and osteolytic lesions.
ROS/p53/miR‑335‑5p/Sp1 axis modulates the migration and epithelial to mesenchymal transition of JEG‑3 cells.
The mechanism of PDA/PEI/5-Fu coated esophageal stent material on inhibiting cancer associated pathological cells.
Hepatocarcinoma-intestine-pancreas/pancreatitis-associated protein (HIP/PAP) confers protection against hepatic fibrosis through downregulation of transforming growth factor β receptor II.
Novel HSP90-PI3K Dual Inhibitor Suppresses Melanoma Cell Proliferation by Interfering with HSP90-EGFR Interaction and Downstream Signaling Pathways.
Retinol-Binding Protein 4 Accelerates Metastatic Spread and Increases Impairment of Blood Flow in Mouse Mammary Gland Tumors.
Transcription co-activator P300 activates Elk1-aPKC-ι signaling mediated epithelial-to-mesenchymal transition and malignancy in hepatocellular carcinoma.
Long non-coding RNA HAL suppresses the migration and invasion of serous ovarian cancer by inhibiting EMT signaling pathway.
Tartrate-Resistant Acid Phosphatase 5/ACP5 Interacts with p53 to Control the Expression of SMAD3 in Lung Adenocarcinoma.
XIAOPI formula inhibits the pre-metastatic niche formation in breast cancer via suppressing TAMs/CXCL1 signaling.
CD73 promotes tumor metastasis by modulating RICS/RhoA signaling and EMT in gastric cancer.
Mutations in the coat complex II component SEC23B promote colorectal cancer metastasis.
HBXIP: a potential prognosis biomarker of colorectal cancer which promotes invasion and migration via epithelial-mesenchymal transition.
A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3-PBX1 and β-catenin-ABCG2 signaling.
HOXD9 promote epithelial-mesenchymal transition and metastasis in colorectal carcinoma.
MicroRNA‑500a‑5p inhibits colorectal cancer cell invasion and epithelial‑mesenchymal transition.
Upregulated NTF4 in colorectal cancer promotes tumor development via regulating autophagy.
Inhibition of miR-574-5p suppresses cell growth and metastasis and enhances chemosensitivity by targeting RNA binding protein QKI in cervical cancer cells.
Anti-human serum albumin autoantibody may be involved in the pathogenesis of autoimmune bullous skin diseases.
Effect of STAT3 mediated epigenetic regulation in pre-eclampsia: an analysis of trial data.
Extracellular vesicles produced by bone marrow mesenchymal stem cells attenuate renal fibrosis, in part by inhibiting the RhoA/ROCK pathway, in a UUO rat model.
Klotho is regulated by transcription factor Sp1 in renal tubular epithelial cells.
M6A-related bioinformatics analysis reveals that HNRNPC facilitates progression of OSCC via EMT.
ARHGEF10L expression regulates cell proliferation and migration in gastric tumorigenesis.
Cyclovirobuxine D inhibits colorectal cancer tumorigenesis via the CTHRC1‑AKT/ERK‑Snail signaling pathway.
PCNP promotes ovarian cancer progression by accelerating β-catenin nuclear accumulation and triggering EMT transition.
The effect of lncRNA-ARAP1-AS2/ARAP1 on high glucose-induced cytoskeleton rearrangement and epithelial-mesenchymal transition in human renal tubular epithelial cells.
LncRNA MALAT1 affects the migration and invasion of trophoblast cells by regulating FOS expression in early-onset preeclampsia.
miR-96-5p regulated TGF-β/SMAD signaling pathway and suppressed endometrial cell viability and migration via targeting TGFBR1.
Alteration of N(6)-methyladenosine epitranscriptome profile in unilateral ureteral obstructive nephropathy.
PD-L1 promotes tumor growth and progression by activating WIP and β-catenin signaling pathways and predicts poor prognosis in lung cancer.
CD147 promotes collective invasion through cathepsin B in hepatocellular carcinoma.
The cross-talk between DDR1 and STAT3 promotes the development of hepatocellular carcinoma.
Long noncoding RNA MAPKAPK5-AS1 promotes colorectal cancer progression by cis-regulating the nearby gene MK5 and acting as a let-7f-1-3p sponge.
Targeted delivery of honokiol by zein/hyaluronic acid core-shell nanoparticles to suppress breast cancer growth and metastasis.
Echinatin suppresses esophageal cancer tumor growth and invasion through inducing AKT/mTOR-dependent autophagy and apoptosis.
CPEB3 inhibits epithelial-mesenchymal transition by disrupting the crosstalk between colorectal cancer cells and tumor-associated macrophages via IL-6R/STAT3 signaling.
Sini San ameliorates duodenal mucosal barrier injury and low‑grade inflammation via the CRF pathway in a rat model of functional dyspepsia.
Long non‑coding RNA HCP5 promotes prostate cancer cell proliferation by acting as the sponge of miR‑4656 to modulate CEMIP expression.
Subcellular trafficking of tubular MDM2 implicates in acute kidney injury to chronic kidney disease transition during multiple low-dose cisplatin exposure.
MiR-490-5p functions as tumor suppressor in childhood neuroblastoma by targeting MYEOV.
Spondin 2 promotes the proliferation, migration and invasion of gastric cancer cells.
Hydroxypropyl‑β‑cyclodextrin attenuates the epithelial‑to‑mesenchymal transition via endoplasmic reticulum stress in MDA‑MB‑231 breast cancer cells.
Norepinephrine transporter promotes the invasion of human colon cancer cells.
The anti-migration and anti-invasion effects of Bruceine D in human triple-negative breast cancer MDA-MB-231 cells.
Long noncoding RNA CASC21 exerts an oncogenic role in colorectal cancer through regulating miR-7-5p/YAP1 axis.
Resveratrol induces depletion of TRAF6 and suppresses prostate cancer cell proliferation and migration.
Upregulation of E-cadherin in bronchoalveolar lavage fluid-derived exosomes in patients with lung cancer.
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer.
Graphene Oxide Causes Disordered Zonation Due to Differential Intralobular Localization in the Liver.
Graphene Oxide Promotes Cancer Metastasis through Associating with Plasma Membrane To Promote TGF-β Signaling-Dependent Epithelial-Mesenchymal Transition.
Telmisartan inhibits oxalate and calcium oxalate crystal-induced epithelial-mesenchymal transformation via PPAR-γ-AKT/STAT3/p38 MAPK-Snail pathway.
FHL3 promotes pancreatic cancer invasion and metastasis through preventing the ubiquitination degradation of EMT associated transcription factors.
A super-enhancer controls TGF- β signaling in pancreatic cancer through downregulation of TGFBR2.
CCND1, NOP14 and DNMT3B are involved in miR-502-5p-mediated inhibition of cell migration and proliferation in bladder cancer.
Epiregulin promotes trophoblast epithelial-mesenchymal transition through poFUT1 and O-fucosylation by poFUT1 on uPA.
eIF4E‑related miR‑320a and miR‑340‑5p inhibit endometrial carcinoma cell metastatic capability by preventing TGF‑β1‑induced epithelial‑mesenchymal transition.
miR-1294 alleviates epithelial-mesenchymal transition by repressing FOXK1 in gastric cancer.
The reciprocal interaction between tumor cells and activated fibroblasts mediated by TNF-α/IL-33/ST2L signaling promotes gastric cancer metastasis.
Berberine inhibits proliferation and migration of colorectal cancer cells by downregulation of GRP78.
Protocatechuic Aldehyde Represses Proliferation and Migration of Breast Cancer Cells through Targeting C-terminal Binding Protein 1.
Expression and clinical significance of WWOX, Elf5, Snail1 and EMT related factors in epithelial ovarian cancer.
PLAGL2 promotes epithelial-mesenchymal transition and mediates colorectal cancer metastasis via β-catenin-dependent regulation of ZEB1.
The lncRNA FEZF1-AS1 Promotes the Progression of Colorectal Cancer Through Regulating OTX1 and Targeting miR-30a-5p.
Knockdown of P3H4 inhibits proliferation and invasion of bladder cancer.
Antisense lncRNA LDLRAD4-AS1 promotes metastasis by decreasing the expression of LDLRAD4 and predicts a poor prognosis in colorectal cancer.
SERPINH1 regulates EMT and gastric cancer metastasis via the Wnt/β-catenin signaling pathway.
Interaction of calcium binding protein S100A16 with myosin-9 promotes cytoskeleton reorganization in renal tubulointerstitial fibrosis.
GRWD1 promotes cell proliferation and migration in non-small cell lung cancer by activating the Notch pathway.
TMEFF2 is a novel prognosis signature and target for endometrial carcinoma.
IL-6 trans-signaling drives a STAT3-dependent pathway that leads to structural alterations of the peritoneal membrane.
YAP activity protects against endotoxemic acute lung injury by activating multiple mechanisms.
The POU2F1/miR-4490/USP22 axis regulates cell proliferation and metastasis in gastric cancer.
Promotion of esophageal adenocarcinoma metastasis via Wnt/ß-catenin signal pathway by sorting nexins 3.
Circ_0075829 facilitates the progression of pancreatic carcinoma by sponging miR-1287-5p and activating LAMTOR3 signalling.
Chinese herbal formula QHF inhibits hepatocellular carcinoma metastasis via HGF/c-Met signaling pathway.
Down-regulation of lncRNA DNAJC3-AS1 inhibits colon cancer via regulating miR-214-3p/LIVIN axis.
Long non-coding RNA PHACTR2-AS1 promotes tongue squamous cell carcinoma metastasis by regulating Snail.
HOXB9 enhances the ability of lung cancer cells to penetrate the blood-brain barrier.
High expression of RRM2 as an independent predictive factor of poor prognosis in patients with lung adenocarcinoma.
Regulation of FN1 degradation by the p62/SQSTM1-dependent autophagy-lysosome pathway in HNSCC.
The peptide mimicking small extracellular ring domain of CD82 inhibits epithelial-mesenchymal transition by downregulating Wnt pathway and upregulating hippo pathway.
Podocyte-derived extracellular vesicles mediate renal proximal tubule cells dedifferentiation via microRNA-221 in diabetic nephropathy.
Silencing of the lncRNA TUG1 attenuates the epithelial-mesenchymal transition of renal tubular epithelial cells by sponging miR-141-3p via regulating β-catenin.
BML-111 inhibits EMT, migration and metastasis of TAMs-stimulated triple-negative breast cancer cells via ILK pathway.
The role of miR-34c-5p/Notch in epithelial-mesenchymal transition (EMT) in endometriosis.
Girdin interaction with vimentin induces EMT and promotes the growth and metastasis of pancreatic ductal adenocarcinoma.
Possible involvement of TGF‑β‑SMAD‑mediated epithelial‑mesenchymal transition in pro‑metastatic property of PAX6.
Maladjustment of β-CGRP/α-CGRP Regulation of AQP5 Promotes Transition of Alveolar Epithelial Cell Apoptosis to Pulmonary Fibrosis.
miR-143 inhibits renal cell carcinoma cells metastatic potential by suppressing ABL2.
Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer.
FoxM1 inhibition ameliorates renal interstitial fibrosis by decreasing extracellular matrix and epithelial-mesenchymal transition.
circ_0007385 served as competing endogenous RNA for miR-519d-3p to suppress malignant behaviors and cisplatin resistance of non-small cell lung cancer cells.
Reelin Promotes Cisplatin Resistance by Induction of Epithelial-Mesenchymal Transition via p38/GSK3β/Snail Signaling in Non-Small Cell Lung Cancer.
Hippuric Acid Promotes Renal Fibrosis by Disrupting Redox Homeostasis via Facilitation of NRF2-KEAP1-CUL3 Interactions in Chronic Kidney Disease.
Role of exosomal microRNA-125b-5p in conferring the metastatic phenotype among pancreatic cancer cells with different potential of metastasis.
MicroRNA-378-3p/5p suppresses the migration and invasiveness of oral squamous carcinoma cells by inhibiting KLK4 expression.
Fangjihuangqi Decoction inhibits MDA-MB-231 cell invasion in vitro and decreases tumor growth and metastasis in triple-negative breast cancer xenografts tumor zebrafish model.
LncRNA LINP1 confers tamoxifen resistance and negatively regulated by ER signaling in breast cancer.
GADD45G Interacts with E-cadherin to Suppress the Migration and Invasion of Esophageal Squamous Cell Carcinoma.
RUNX3 inhibits the invasion and migration of esophageal squamous cell carcinoma by reversing the epithelial‑mesenchymal transition through TGF‑β/Smad signaling.
Downregulation of MiD49 contributes to tumor growth and metastasis of human pancreatic cancer.
METTL3/YTHDF2 m(6) A axis promotes tumorigenesis by degrading SETD7 and KLF4 mRNAs in bladder cancer.
BHLHE41 suppresses MCF-7 cell invasion via MAPK/JNK pathway.
Sirt6 attenuates hypoxia-induced tubular epithelial cell injury via targeting G2/M phase arrest.
Stromal fibroblast-derived MFAP5 promotes the invasion and migration of breast cancer cells via Notch1/slug signaling.
Novel nortriterpenoids with new skeletons and limonoids from the fruits of Evodia rutaecarpa and their bioactivities.
Cullin-7 (CUL7) is overexpressed in glioma cells and promotes tumorigenesis via NF-κB activation.
Micro-vesicles from mesenchymal stem cells over-expressing miR-34a inhibit transforming growth factor-β1-induced epithelial-mesenchymal transition in renal tubular epithelial cells in vitro.
The YY1/miR-548t-5p/CXCL11 signaling axis regulates cell proliferation and metastasis in human pancreatic cancer.
CCL5 derived from tumor-associated macrophages promotes prostate cancer stem cells and metastasis via activating β-catenin/STAT3 signaling.
Fermented blueberry pomace ameliorates intestinal barrier function through the NF-κB-MLCK signaling pathway in high-fat diet mice.
MicroRNA-23a-3p Inhibits Mucosal Melanoma Growth and Progression through Targeting Adenylate Cyclase 1 and Attenuating cAMP and MAPK Pathways.
Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis.
Temporal inhibition of mouse mammary gland cancer metastasis by CORM-A1 and DETA/NO combination therapy.
SORBS2, mediated by MEF2D, suppresses the metastasis of human hepatocellular carcinoma by inhibitiing the c-Abl-ERK signaling pathway.
SERPIND1 Affects the Malignant Biological Behavior of Epithelial Ovarian Cancer via the PI3K/AKT Pathway: A Mechanistic Study.
CAPE-pNO(2) Inhibited the Growth and Metastasis of Triple-Negative Breast Cancer via the EGFR/STAT3/Akt/E-Cadherin Signaling Pathway.
Identification of RE1-Silencing Transcription Factor as a Promoter of Metastasis in Pancreatic Cancer.
Scorpion Venom Analgesic Peptide, BmK AGAP Inhibits Stemness, and Epithelial-Mesenchymal Transition by Down-Regulating PTX3 in Breast Cancer.
LncRNA SNHG16 promotes epithelial- mesenchymal transition via down-regulation of DKK3 in gastric cancer.
LncRNA ZFAS1 promotes proliferation and migration and inhibits apoptosis in nasopharyngeal carcinoma via the PI3K/AKT pathway in vitro.
The long noncoding RNA LINC00483 promotes lung adenocarcinoma progression by sponging miR-204-3p.
Downregulation of CDKL1 suppresses neuroblastoma cell proliferation, migration and invasion.
Betulinic Acid Suppresses Breast Cancer Metastasis by Targeting GRP78-Mediated Glycolysis and ER Stress Apoptotic Pathway.
Dual-target MDM2/MDMX inhibitor increases the sensitization of doxorubicin and inhibits migration and invasion abilities of triple-negative breast cancer cells through activation of TAB1/TAK1/p38 MAPK pathway.
2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol reverses EGF-induced cell migration and invasion through down-regulation of MDM2 in breast cancer cell lines.
SKA1 promotes malignant phenotype and progression of glioma via multiple signaling pathways.
Strand-specific miR-28-3p and miR-28-5p have differential effects on nasopharyngeal cancer cells proliferation, apoptosis, migration and invasion.
TGF-β1 Induces Epithelial-Mesenchymal Transition of Chronic Sinusitis with Nasal Polyps through MicroRNA-21.
A panel of biomarkers for skin squamous cell carcinoma: various functional entities and differential responses to resveratrol.
CLK3 Is A Direct Target Of miR-144 And Contributes To Aggressive Progression In Hepatocellular Carcinoma.
Silencing of CARMA3 inhibits bladder cancer cell migration and invasion via deactivating β-catenin signaling pathway.
ODC1 promotes proliferation and mobility via the AKT/GSK3β/β-catenin pathway and modulation of acidotic microenvironment in human hepatocellular carcinoma.
Exosomal Tenascin-c induces proliferation and invasion of pancreatic cancer cells by WNT signaling.
High expression of long non-coding RNA NNT-AS1 facilitates progression of cholangiocarcinoma through promoting epithelial-mesenchymal transition.
Long noncoding RNA CASC15 predicts unfavorable prognosis and exerts oncogenic functions in non-small cell lung cancer.
EYA1 promotes cell migration and tumor metastasis in hepatocellular carcinoma.
Blocking transforming growth factor-beta reduces the migration and invasion of the residual tumour after TAE.
Long noncoding RNA HCP5 contributes to epithelial-mesenchymal transition in colorectal cancer through ZEB1 activation and interacting with miR-139-5p.
Lipase member H is a downstream molecular target of hypoxia inducible factor-1α and promotes papillary thyroid carcinoma cell migration in BCPAP and KTC-1 cell lines.
TMEFF1 overexpression and its mechanism for tumor promotion in ovarian cancer.
Overexpressed PKMYT1 promotes tumor progression and associates with poor survival in esophageal squamous cell carcinoma.
Disulfiram inhibits epithelial-mesenchymal transition through TGFβ-ERK-Snail pathway independently of Smad4 to decrease oral squamous cell carcinoma metastasis.
The oncogenic role of GNL3 in the progression and metastasis of osteosarcoma.
Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway.
RUFY3 Predicts Poor Prognosis and Promotes Metastasis through Epithelial-mesenchymal Transition in Lung Adenocarcinoma.
Verteporfin suppresses the proliferation, epithelial-mesenchymal transition and stemness of head and neck squamous carcinoma cells via inhibiting YAP1.
Dysregulation of MiR-519d Affects Oral Squamous Cell Carcinoma Invasion and Metastasis by Targeting MMP3.
Small Nucleolar RNA 71A Promotes Lung Cancer Cell Proliferation, Migration and Invasion via MAPK/ERK Pathway.
MicroRNA-532-3p Suppresses Malignant Behaviors of Tongue Squamous Cell Carcinoma via Regulating CCR7.
Activation of CXCL6/CXCR1/2 Axis Promotes the Growth and Metastasis of Osteosarcoma Cells in vitro and in vivo.
Biomimetic Human Tissue Model for Long-Term Study of Neisseria gonorrhoeae Infection.
Knockdown of SP1/Syncytin1 axis inhibits the proliferation and metastasis through the AKT and ERK1/2 signaling pathways in non-small cell lung cancer.
Nonconserved miR-608 suppresses prostate cancer progression through RAC2/PAK4/LIMK1 and BCL2L1/caspase-3 pathways by targeting the 3'-UTRs of RAC2/BCL2L1 and the coding region of PAK4.
Overexpression of matrix metalloproteinase-9 in breast cancer cell lines remarkably increases the cell malignancy largely via activation of transforming growth factor beta/SMAD signalling.
Transforming growth factor β1 promotes fibroblast-like synoviocytes migration and invasion via TGF-β1/Smad signaling in rheumatoid arthritis.
Fluorene-9-bisphenol inhibits epithelial-mesenchymal transition of human endometrial cancer Ishikawa cells by repressing TGF-β signaling pathway.
Thioredoxin-interacting protein deficiency alleviates phenotypic alterations of podocytes via inhibition of mTOR activation in diabetic nephropathy.
Astaxanthin protects against renal fibrosis through inhibiting myofibroblast activation and promoting CD8(+) T cell recruitment.
Downregulated lncRNA UCA1 acts as ceRNA to adsorb microRNA-498 to repress proliferation, invasion and epithelial mesenchymal transition of esophageal cancer cells by decreasing ZEB2 expression.
MicroRNA-330-3p promotes brain metastasis and epithelial-mesenchymal transition via GRIA3 in non-small cell lung cancer.
Long non-coding RNA linc00645 promotes TGF-β-induced epithelial-mesenchymal transition by regulating miR-205-3p-ZEB1 axis in glioma.
KIF18A promotes head and neck squamous cell carcinoma invasion and migration via activation of Akt signaling pathway.
Sulforaphane inhibits epithelial-mesenchymal transition by activating extracellular signal-regulated kinase 5 in lung cancer cells.
Macrophage migration inhibitory factor promotes the invasion and metastasis of oral squamous cell carcinoma through matrix metalloprotein-2/9.
AEBP1, a prognostic indicator, promotes colon adenocarcinoma cell growth and metastasis through the NF-κB pathway.
Downregulation of nicotinamide N-methyltransferase inhibits migration and epithelial-mesenchymal transition of esophageal squamous cell carcinoma via Wnt/β-catenin pathway.
A novel tetravalent bispecific antibody targeting programmed death 1 and tyrosine-protein kinase Met for treatment of gastric cancer.
Wnt7a, frequently silenced by CpG methylation, inhibits tumor growth and metastasis via suppressing epithelial-mesenchymal transition in gastric cancer.
Chronic CagA-positive Helicobacter pylori infection with MNNG stimulation synergistically induces mesenchymal and cancer stem cell-like properties in gastric mucosal epithelial cells.
Inhibition of high mobility group box 1 (HMGB1) attenuates podocyte apoptosis and epithelial-mesenchymal transition by regulating autophagy flux.
CircWHSC1 promotes ovarian cancer progression by regulating MUC1 and hTERT through sponging miR-145 and miR-1182.
CD36 promotes the epithelial-mesenchymal transition and metastasis in cervical cancer by interacting with TGF-β.
Discovery of Novel Aryl Carboxamide Derivatives as Hypoxia-Inducible Factor 1α Signaling Inhibitors with Potent Activities of Anticancer Metastasis.
Functional genetic variants of RUVBL1 predict overall survival of Chinese patients with epithelial ovarian cancer.
Influence of Wilms' tumor suppressor gene WT1 on bovine Sertoli cells polarity and tight junctions via non-canonical WNT signaling pathway.
Tumor-suppressive activity of Hnf1β in Wilms' tumor.
Curcumin mitigates the epithelial-to-mesenchymal transition in biliary epithelial cells through upregulating CD109 expression.
O‑GlcNAc modification influences endometrial receptivity by promoting endometrial cell proliferation, migration and invasion.
Dehydrogenase/reductase SDR family member 2 silencing sensitizes an oxaliplatin‑resistant cell line to oxaliplatin by inhibiting excision repair cross‑complementing group 1 protein expression.
Niban protein regulates apoptosis in HK-2 cells via caspase-dependent pathway.
The protective effect of lithocholic acid on the intestinal epithelial barrier is mediated by the vitamin D receptor via a SIRT1/Nrf2 and NF-κB dependent mechanism in Caco-2 cells.
Long-term exposure of 4-hydroxyestradiol induces the cancer cell characteristics via upregulating CYP1B1 in MCF-10A cells.
miR-611 promotes the proliferation, migration and invasion of tongue squamous cell carcinoma cells by targeting FOXN3.
The miR-27a-3p/USP25 axis participates in the pathogenesis of recurrent miscarriage by inhibiting trophoblast migration and invasion.
Sirtuin6 (SIRT6) Promotes the EMT of Hepatocellular Carcinoma by Stimulating Autophagic Degradation of E-Cadherin.
Downregulation of Rab23 inhibits proliferation, invasion, and metastasis of human ovarian cancer.
G9a and histone deacetylases are crucial for Snail2-mediated E-cadherin repression and metastasis in hepatocellular carcinoma.
PITPNA-AS1 abrogates the inhibition of miR-876-5p on WNT5A to facilitate hepatocellular carcinoma progression.
Inhibiting Hypoxia and Chemotherapy-Induced Cancer Cell Metastasis under a Valid Therapeutic Effect by an Assistance of Biomimetic Oxygen Delivery.
Targetting an LncRNA P5848-ENO1 axis inhibits tumor growth in hepatocellular carcinoma.
Rhomboid-Like-2 Intramembrane Protease Mediates Metalloprotease-Independent Regulation of Cadherins.
Sinulariolide Inhibits Gastric Cancer Cell Migration and Invasion through Downregulation of the EMT Process and Suppression of FAK/PI3K/AKT/mTOR and MAPKs Signaling Pathways.
β2AR-HIF-1α-CXCL12 signaling of osteoblasts activated by isoproterenol promotes migration and invasion of prostate cancer cells.
DEK Is a Potential Biomarker Associated with Malignant Phenotype in Gastric Cancer Tissues and Plasma.
Amphiregulin promotes trophoblast invasion and increases MMP9/TIMP1 ratio through ERK1/2 and Akt signal pathways.
Zinc promotes prostate cancer cell chemosensitivity to paclitaxel by inhibiting epithelial-mesenchymal transition and inducing apoptosis.
Hypoxia promotes vasculogenic mimicry formation by vascular endothelial growth factor A mediating epithelial-mesenchymal transition in salivary adenoid cystic carcinoma.
RPS7 promotes cell migration through targeting epithelial-mesenchymal transition in prostate cancer.
SREBP1, targeted by miR-18a-5p, modulates epithelial-mesenchymal transition in breast cancer via forming a co-repressor complex with Snail and HDAC1/2.
Upregulation of lncRNA DGCR5 correlates with better prognosis and inhibits bladder cancer progression via transcriptionally facilitating P21 expression.
SSRP1 promotes colorectal cancer progression and is negatively regulated by miR-28-5p.
Expansion and maintenance of primary corneal epithelial stem/progenitor cells by inhibition of TGFβ receptor I-mediated signaling.
Upregulated forkhead-box A3 elevates the expression of forkhead-box A1 and forkhead-box A2 to promote metastasis in esophageal cancer.
MicroRNA-34a Promotes Renal Fibrosis by Downregulation of Klotho in Tubular Epithelial Cells.
miR-340-FHL2 axis inhibits cell growth and metastasis in ovarian cancer.
Transcriptional control of subtype switching ensures adaptation and growth of pancreatic cancer.
The HBx-CTTN interaction promotes cell proliferation and migration of hepatocellular carcinoma via CREB1.
M2 macrophages promote NSCLC metastasis by upregulating CRYAB.
Triptolide prevents proliferation and migration of Esophageal Squamous Cell Cancer via MAPK/ERK signaling pathway.
CXCL12/CXCR4 pathway orchestrates CSC-like properties by CAF recruited tumor associated macrophage in OSCC.
miR-130a-3p regulated TGF-β1-induced epithelial-mesenchymal transition depends on SMAD4 in EC-1 cells.
lncRNA H19 promotes viability and epithelial-mesenchymal transition of lung adenocarcinoma cells by targeting miR-29b-3p and modifying STAT3.
Stanniocalcin‑1 promotes cell proliferation, chemoresistance and metastasis in hypoxic gastric cancer cells via Bcl‑2.
PTEN downregulates WD repeat‑containing protein 66 in salivary adenoid cystic carcinoma.
Wnt7a predicts poor prognosis, and contributes to growth and metastasis in tongue squamous cell carcinoma.
Tn antigen promotes human colorectal cancer metastasis via H-Ras mediated epithelial-mesenchymal transition activation.
Epithelial‑mesenchymal transition induced by bone morphogenetic protein 9 hinders cisplatin efficacy in ovarian cancer cells.
LncRNA MIR22HG inhibits growth, migration and invasion through regulating the miR-10a-5p/NCOR2 axis in hepatocellular carcinoma cells.
Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway.
Cysteine Dioxygenase Regulates the Epithelial Morphogenesis of Mammary Gland via Cysteine Sulfinic Acid.
CUL4B promotes prostate cancer progression by forming positive feedback loop with SOX4.
AKR1B10 (Aldo-keto reductase family 1 B10) promotes brain metastasis of lung cancer cells in a multi-organ microfluidic chip model.
Protective effect of rosiglitazone on chronic renal allograft dysfunction in rats.
Bronchial epithelial cell extracellular vesicles ameliorate epithelial-mesenchymal transition in COPD pathogenesis by alleviating M2 macrophage polarization.
Expression of miR-181a and TGF-β2 in lens epithelial cells of patients with cataractous retinal detachment and its clinical significance.
Platelets promote invasion and induce epithelial to mesenchymal transition in ovarian cancer cells by TGF-β signaling pathway.
circ-CSPP1 promotes proliferation, invasion and migration of ovarian cancer cells by acting as a miR-1236-3p sponge.
CBLL1 is highly expressed in non-small cell lung cancer and promotes cell proliferation and invasion.
Calcium-Activated Chloride Channel A4 (CLCA4) Plays Inhibitory Roles in Invasion and Migration Through Suppressing Epithelial-Mesenchymal Transition via PI3K/AKT Signaling in Colorectal Cancer.
TRIP4 promotes tumor growth and metastasis and regulates radiosensitivity of cervical cancer by activating MAPK, PI3K/AKT, and hTERT signaling.
Acetylation of PHF5A Modulates Stress Responses and Colorectal Carcinogenesis through Alternative Splicing-Mediated Upregulation of KDM3A.
NAV2 facilitates invasion of cutaneous melanoma cells by targeting SNAI2 through the GSK-3β/β-catenin pathway.
Exogenous regucalcin negatively regulates the progression of cervical adenocarcinoma.
PKM2-regulated STAT3 promotes esophageal squamous cell carcinoma progression via TGF-β1-induced EMT.
Melatonin prevents lung injury by regulating apelin 13 to improve mitochondrial dysfunction.
MicroRNA-23a promotes colorectal cancer cell migration and proliferation by targeting at MARK1.
METTL7B promotes migration and invasion in thyroid cancer through epithelial-mesenchymal transition.
Dual regulatory role of CCNA2 in modulating CDK6 and MET-mediated cell-cycle pathway and EMT progression is blocked by miR-381-3p in bladder cancer.
Chromium(VI) promotes cell migration through targeting epithelial-mesenchymal transition in prostate cancer.
FOXC1 silencing inhibits the epithelial‑to‑mesenchymal transition of glioma cells: Involvement of β‑catenin signaling.
Everolimus Reverses Palbociclib Resistance in ER+ Human Breast Cancer Cells by Inhibiting Phosphatidylinositol 3-Kinase(PI3K)/Akt/Mammalian Target of Rapamycin (mTOR) Pathway.
Tobacco smoke induced hepatic cancer stem cell-like properties through IL-33/p38 pathway.
DHA-phospholipids (DHA-PL) and EPA-phospholipids (EPA-PL) prevent intestinal dysfunction induced by chronic stress.
Inhibition of ATP citrate lyase (ACLY) protects airway epithelia from PM(2.5)-induced epithelial-mesenchymal transition.
ARHGEF10L contributes to liver tumorigenesis through RhoA-ROCK1 signaling and the epithelial-mesenchymal transition.
Native nanodiscs from blood inhibit pulmonary fibrosis.
Sphingomyelin synthase 1 regulates the epithelial‑to‑mesenchymal transition mediated by the TGF‑β/Smad pathway in MDA‑MB‑231 cells.
Melatonin synergizes BRAF-targeting agent vemurafenib in melanoma treatment by inhibiting iNOS/hTERT signaling and cancer-stem cell traits.
LincK contributes to breast tumorigenesis by promoting proliferation and epithelial-to-mesenchymal transition.
Zoledronic acid inhibits the growth of cancer stem cell derived from cervical cancer cell by attenuating their stemness phenotype and inducing apoptosis and cell cycle arrest through the Erk1/2 and Akt pathways.
P53-induced miR-1249 inhibits tumor growth, metastasis, and angiogenesis by targeting VEGFA and HMGA2.
Upregulation of microRNA-133a and downregulation of connective tissue growth factor suppress cell proliferation, migration, and invasion in human glioma through the JAK/STAT signaling pathway.
Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3Kα) against cutaneous melanoma.
Knockdown of periostin attenuates 5/6 nephrectomy-induced intrarenal renin-angiotensin system activation, fibrosis, and inflammation in rats.
Histone deacetylases inhibitor MS-275 suppresses human esophageal squamous cell carcinoma cell growth and progression via the PI3K/Akt/mTOR pathway.
Downregulation of HDAC3 by ginsenoside Rg3 inhibits epithelial-mesenchymal transition of cutaneous squamous cell carcinoma through c-Jun acetylation.
miR-451a inhibits cancer growth, epithelial-mesenchymal transition and induces apoptosis in papillary thyroid cancer by targeting PSMB8.
Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression.
Six2 is negatively correlated with prognosis and facilitates epithelial-mesenchymal transition via TGF-β/Smad signal pathway in hepatocellular carcinoma.
Snail2 induced E-cadherin suppression and metastasis in lung carcinoma facilitated by G9a and HDACs.
BECN1 promotes the migration of NSCLC cells through regulating the ubiquitination of Vimentin.
Ticagrelor and clopidogrel suppress NF-κB signaling pathway to alleviate LPS-induced dysfunction in vein endothelial cells.
Hsa_circ_0006948 enhances cancer progression and epithelial-mesenchymal transition through the miR-490-3p/HMGA2 axis in esophageal squamous cell carcinoma.
Disruption of Cancer Metabolic SREBP1/miR-142-5p Suppresses Epithelial-Mesenchymal Transition and Stemness in Esophageal Carcinoma.
PAMAM-cRGD mediating efficient siRNA delivery to spermatogonial stem cells.
A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice.
CLDN6 promotes tumor progression through the YAP1-snail1 axis in gastric cancer.
Silencing TTK expression inhibits the proliferation and progression of prostate cancer.
MicroRNA-3666 inhibits lung cancer cell proliferation, migration, and invasiveness by targeting BPTF.
Long non-coding RNA miR143HG predicts good prognosis and inhibits tumor multiplication and metastasis by suppressing mitogen-activated protein kinase and Wnt signaling pathways in hepatocellular carcinoma.
Intergrated analysis of ELMO1, serves as a link between tumour mutation burden and epithelial-mesenchymal transition in hepatocellular carcinoma.
miR-205-5p regulates epithelial-mesenchymal transition by targeting PTEN via PI3K/AKT signaling pathway in cisplatin-resistant nasopharyngeal carcinoma cells.
miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt-β-catenin pathway.
EMT-related protein expression in polyploid giant cancer cells and their daughter cells with different passages after triptolide treatment.
TGF-β-mediated upregulation of brachyury contributes to constitutively up-regulated type I collagen expression in skin fibroblasts: possible role in systemic sclerosis.
Down-regulation of lncRNA-ATB inhibits epithelial-mesenchymal transition of breast cancer cells by increasing miR-141-3p expression.
LncRNA THOR increases osteosarcoma cell stemness and migration by enhancing SOX9 mRNA stability.
LncRNA H19 interacted with miR-130a-3p and miR-17-5p to modify radio-resistance and chemo-sensitivity of cardiac carcinoma cells.
A mechanism of regucalcin knock-down in the promotion of proliferation and movement of human cervical cancer HeLa cells.
Netrin‑1 interference potentiates epithelial‑to‑mesenchymal transition through the PI3K/AKT pathway under the hypoxic microenvironment conditions of non‑small cell lung cancer.
Cathepsin B defines leader cells during the collective invasion of salivary adenoid cystic carcinoma.
Effects of SIRT1 silencing on viability, invasion and metastasis of human glioma cell lines.
Bone marrow mesenchymal stem cells suppress growth and promote the apoptosis of glioma U251 cells through downregulation of the PI3K/AKT signaling pathway.
Network-pharmacology-based identification of caveolin-1 as a key target of Oldenlandia diffusa to suppress breast cancer metastasis.
Knockdown on aPKC-ι inhibits epithelial-mesenchymal transition, migration and invasion of colorectal cancer cells through Rac1-JNK pathway.
GTSE1 is involved in breast cancer progression in p53 mutation-dependent manner.
The PAX6-ZEB2 axis promotes metastasis and cisplatin resistance in non-small cell lung cancer through PI3K/AKT signaling.
Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance.
S100A4-MYH9 Axis Promote Migration and Invasion of Gastric Cancer Cells by Inducing TGF-β-Mediated Epithelial-Mesenchymal Transition.
AMPH-1 is critical for breast cancer progression.
Cisatracurium Retards Cell Migration and Invasion Upon Upregulation of p53 and Inhibits the Aggressiveness of Colorectal Cancer.
Keratinocytes Isolated From Individual Cleft Lip/Palate Patients Display Variations in Their Differentiation Potential in vitro.
MicroRNA-506 suppresses invasiveness and metastasis of human hepatocellular carcinoma cells by targeting IL8.
Add-On therapy with Chinese herb medicine Bo-Er-Ning capsule (BENC) improves outcomes of gastric cancer patients: a randomized clinical trial followed with bioinformatics-assisted mechanism study.
miR-200c/141 Regulates Breast Cancer Stem Cell Heterogeneity via Targeting HIPK1/β-Catenin Axis.
Tip60 Suppresses Cholangiocarcinoma Proliferation and Metastasis via PI3k-AKT.
Formation of Human Colonic Crypt Array by Application of Chemical Gradients Across a Shaped Epithelial Monolayer.
The Natural Compound Myricetin Effectively Represses the Malignant Progression of Prostate Cancer by Inhibiting PIM1 and Disrupting the PIM1/CXCR4 Interaction.
MiR-598 Suppresses Invasion and Migration by Negative Regulation of Derlin-1 and Epithelial-Mesenchymal Transition in Non-Small Cell Lung Cancer.
C/D-Box Snord105b Promotes Tumorigenesis in Gastric Cancer via ALDOA/C-Myc Pathway.
Simulated Cholinergic Reinnervation of β (INS-1) Cells: Antidiabetic Utility of Heterotypic Pseudoislets Containing β Cell and Cholinergic Cell.
Silencing Formin-like 2 inhibits growth and metastasis of gastric cancer cells through suppressing internalization of integrins.
Tumor-associated macrophages derived CCL18 promotes metastasis in squamous cell carcinoma of the head and neck.
NANOGP8 is the key regulator of stemness, EMT, Wnt pathway, chemoresistance, and other malignant phenotypes in gastric cancer cells.
Overexpression of FAM3C protein as a novel biomarker for epithelial-mesenchymal transition and poor outcome in gastric cancer.
Overexpression of TEAD4 correlates with poor prognosis of glioma and promotes cell invasion.
EDIL3 depletion suppress epithelial-mesenchymal transition of lens epithelial cells via transforming growth factor β pathway.
KIAA1199 overexpression is associated with abnormal expression of EMT markers and is a novel independent prognostic biomarker for hepatocellular carcinoma.
Contribution of dysregulated circRNA_100876 to proliferation and metastasis of esophageal squamous cell carcinoma.
Phenformin and metformin inhibit growth and migration of LN229 glioma cells in vitro and in vivo.
SIRT1 overexpression protects non-small cell lung cancer cells against osteopontin-induced epithelial-mesenchymal transition by suppressing NF-κB signaling.
Interaction with SP1, but not binding to the E-box motifs, is responsible for BHLHE40/DEC1-induced transcriptional suppression of CLDN1 and cell invasion in MCF-7 cells.
Polyphyllin I inhibits invasion and epithelial-mesenchymal transition via CIP2A/PP2A/ERK signaling in prostate cancer.
Stromal expression of JNK1 and VDR is associated with the prognosis of esophageal squamous cell carcinoma.
Tanshinone IIA inhibits cervix carcinoma stem cells migration and invasion via inhibiting YAP transcriptional activity.
Effect of simvastatin and microRNA-21 inhibitor on metastasis and progression of human salivary adenoid cystic carcinoma.
SNORA42 enhances prostate cancer cell viability, migration and EMT and is correlated with prostate cancer poor prognosis.
MiR-455-3p suppresses renal fibrosis through repression of ROCK2 expression in diabetic nephropathy.
S3I-201 ameliorates tubulointerstitial lesion of the kidneys in MRL/lpr mice.
DDX5 promotes hepatocellular carcinoma tumorigenesis via Akt signaling pathway.
TGF-β-mediated exosomal lnc-MMP2-2 regulates migration and invasion of lung cancer cells to the vasculature by promoting MMP2 expression.
MiR-616-3p modulates cell proliferation and migration through targeting tissue factor pathway inhibitor 2 in preeclampsia.
Selenium (Na(2)SeO(3)) Upregulates Expression of Immune Genes and Blood-Testis Barrier Constituent Proteins of Bovine Sertoli Cell In Vitro.
Low-Dose Radiation Enhanced Inhibition of Breast Tumor Xenograft and Reduced Myocardial Injury Induced by Doxorubicin.
High expression of WNT7A predicts poor prognosis and promote tumor metastasis in pancreatic ductal adenocarcinoma.
Periostin secreted by cancer-associated fibroblasts promotes cancer stemness in head and neck cancer by activating protein tyrosine kinase 7.
Reduced graphene oxide triggered epithelial-mesenchymal transition in A549 cells.
DNA-methylation-mediated silencing of miR-486-5p promotes colorectal cancer proliferation and migration through activation of PLAGL2/IGF2/β-catenin signal pathways.
Knockdown of NLRP3 alleviates high glucose or TGFB1-induced EMT in human renal tubular cells.
Identification and characterization of a highly metastatic epithelial cancer cell line from rat tongue cancer.
LncRNA UCA1 is necessary for TGF-β-induced epithelial-mesenchymal transition and stemness via acting as a ceRNA for Slug in glioma cells.
RNA interference of long noncoding RNA HOTAIR suppresses autophagy and promotes apoptosis and sensitivity to cisplatin in oral squamous cell carcinoma.
MiR-122 inhibits epithelial mesenchymal transition by regulating P4HA1 in ovarian cancer cells.
Abrogation of glutathione peroxidase-1 drives EMT and chemoresistance in pancreatic cancer by activating ROS-mediated Akt/GSK3β/Snail signaling.
Silencing of rhomboid domain containing 1 to inhibit the metastasis of human breast cancer cells in vitro.
A gene mutation in RNA-binding protein 10 is associated with lung adenocarcinoma progression and poor prognosis.
Isoliquiritigenin inhibits cell proliferation and migration through the PI3K/AKT signaling pathway in A549 lung cancer cells.
Effects of PLK1 on proliferation, invasion and metastasis of gastric cancer cells through epithelial-mesenchymal transition.
Toll-like receptor 4 shRNA attenuates lipopolysaccharide-induced epithelial-mesenchymal transition of intrahepatic biliary epithelial cells in rats.
Combination Therapy with DETA/NO and Clopidogrel Inhibits Metastasis in Murine Mammary Gland Cancer Models via Improved Vasoprotection.
Abnormally elevated USP37 expression in breast cancer stem cells regulates stemness, epithelial-mesenchymal transition and cisplatin sensitivity.
The HER4-YAP1 axis promotes trastuzumab resistance in HER2-positive gastric cancer by inducing epithelial and mesenchymal transition.
CD74-ROS1 G2032R mutation transcriptionally up-regulates Twist1 in non-small cell lung cancer cells leading to increased migration, invasion, and resistance to crizotinib.
Krüppel-like Factor 4 Suppresses Serine/Threonine Kinase 33 Activation and Metastasis of Gastric Cancer through Reversing Epithelial-Mesenchymal Transition.
Silencing of lncRNA ZFAS1 inhibits malignancies by blocking Wnt/β-catenin signaling in gastric cancer cells.
Dysregulated Expression of RPS4Y1 (Ribosomal Protein S4, Y-Linked 1) Impairs STAT3 (Signal Transducer and Activator of Transcription 3) Signaling to Suppress Trophoblast Cell Migration and Invasion in Preeclampsia.
NEK2 promotes hepatocellular carcinoma migration and invasion through modulation of the epithelial-mesenchymal transition.
Short interfering RNA-mediated silencing of actin-related protein 2/3 complex subunit 4 inhibits the migration of SW620 human colorectal cancer cells.
Targeting of NT5E by miR-30b and miR-340 attenuates proliferation, invasion and migration of gallbladder carcinoma.
MicroRNA-140 Inhibits the Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer.
SEC-induced activation of ANXA7 GTPase suppresses prostate cancer metastasis.
Systematic analyses reveal long non-coding RNA (PTAF)-mediated promotion of EMT and invasion-metastasis in serous ovarian cancer.
LncRNA SNHG7 sponges miR-216b to promote proliferation and liver metastasis of colorectal cancer through upregulating GALNT1.
Matrine inhibits the invasive and migratory properties of human hepatocellular carcinoma by regulating epithelial‑mesenchymal transition.
Deacetylmycoepoxydiene is an agonist of Rac1, and simultaneously induces autophagy and apoptosis.
Formation of arrays of planar, murine, intestinal crypts possessing a stem/proliferative cell compartment and differentiated cell zone.
RHBDF1 regulates APC-mediated stimulation of the epithelial-to-mesenchymal transition and proliferation of colorectal cancer cells in part via the Wnt/β-catenin signalling pathway.
ADAM12 induces EMT and promotes cell migration, invasion and proliferation in pituitary adenomas via EGFR/ERK signaling pathway.
β-Arrestin-1 deficiency ameliorates renal interstitial fibrosis by blocking Wnt1/β-catenin signaling in mice.
Unfavorable effect of calcitriol and its low-calcemic analogs on metastasis of 4T1 mouse mammary gland cancer.
PLCD3, a flotillin2-interacting protein, is involved in proliferation, migration and invasion of nasopharyngeal carcinoma cells.
Silencing of CEMIP suppresses Wnt/β-catenin/Snail signaling transduction and inhibits EMT program of colorectal cancer cells.
Downregulation of N(6)-methyladenosine binding YTHDF2 protein mediated by miR-493-3p suppresses prostate cancer by elevating N(6)-methyladenosine levels.
Dewetting of Thin Liquid Films Surrounding Air Bubbles in Microchannels.
Downregulation of annexin A3 inhibits tumor metastasis and decreases drug resistance in breast cancer.
PLZF inhibits proliferation and metastasis of gallbladder cancer by regulating IFIT2.
Increased Expression of Cullin 3 in Nasopharyngeal Carcinoma and Knockdown Inhibits Proliferation and Invasion.
HOXC8 promotes proliferation and migration through transcriptional up-regulation of TGFβ1 in non-small cell lung cancer.
Up-regulated lnc-SNHG1 contributes to osteosarcoma progression through sequestration of miR-577 and activation of WNT2B/Wnt/β-catenin pathway.
UNC0638, a G9a inhibitor, suppresses epithelial‑mesenchymal transition‑mediated cellular migration and invasion in triple negative breast cancer.
Carnosol-mediated Sirtuin 1 activation inhibits Enhancer of Zeste Homolog 2 to attenuate liver fibrosis.
Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial-mesenchymal transition and stemness.
Collagen-based three-dimensional culture microenvironment promotes epithelial to mesenchymal transition and drug resistance of human ovarian cancer in vitro.
PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis.
PMLIV overexpression promotes TGF-β-associated epithelial-mesenchymal transition and migration in MCF-7 cancer cells.
Glutathione reductase-mediated thiol oxidative stress suppresses metastasis of murine melanoma cells.
A CREB1/miR-433 reciprocal feedback loop modulates proliferation and metastasis in colorectal cancer.
Salinomycin suppresses cancer cell stemness and attenuates TGF-β-induced epithelial-mesenchymal transition of renal cell carcinoma cells.
Synthesis and Discovery Novel Anti-Cancer Stem Cells Compounds Derived from the Natural Triterpenoic Acids.
Epigenetic suppression of E-cadherin expression by Snail2 during the metastasis of colorectal cancer.
Mitochondrial cytochrome P450 (CYP) 1B1 is responsible for melatonin-induced apoptosis in neural cancer cells.
Circadian regulator NR1D2 regulates glioblastoma cell proliferation and motility.
LncRNA BDNF-AS inhibits proliferation, migration, invasion and EMT in oesophageal cancer cells by targeting miR-214.
Suppressed epithelial-mesenchymal transition and cancer stem cell properties mediate the anti-cancer effects of ethyl pyruvate via regulation of the AKT/nuclear factor-κB pathway in prostate cancer cells.
The gastric mucosal protective effects of astragaloside IV in mnng-induced GPL rats.
Phosphoglycerate Mutase 1 (PGAM1) Promotes Pancreatic Ductal Adenocarcinoma (PDAC) Metastasis by Acting as a Novel Downstream Target of the PI3K/Akt/mTOR Pathway.
Hypoxic Tumor-Derived Exosomal miR-301a Mediates M2 Macrophage Polarization via PTEN/PI3Kγ to Promote Pancreatic Cancer Metastasis.
LncRNA PTAR promotes EMT and invasion-metastasis in serous ovarian cancer by competitively binding miR-101-3p to regulate ZEB1 expression.
Ezrin/NF-κB Pathway Regulates EGF-induced Epithelial-Mesenchymal Transition (EMT), Metastasis, and Progression of Osteosarcoma.
GRHL2 suppresses tumor metastasis via regulation of transcriptional activity of RhoG in non-small cell lung cancer.
Elevated expression of Derlin-1 associates with unfavorable survival time of squamous cell carcinoma of the head and neck and promotes its malignance.
Fentanyl Promotes Breast Cancer Cell Stemness and Epithelial-Mesenchymal Transition by Upregulating α1, 6-Fucosylation via Wnt/β-Catenin Signaling Pathway.
MiR-200c Inhibits the Tumor Progression of Glioma via Targeting Moesin.
Material-induced Senescence (MIS): Fluidity Induces Senescent Type Cell Death of Lung Cancer Cells via Insulin-Like Growth Factor Binding Protein 5.
MiR-98 inhibits malignant progression via targeting MTDH in squamous cell carcinoma of the head and neck.
β-Catenin Cooperates with CREB Binding Protein to Promote the Growth of Tumor Cells.
Anti-OSM Antibody Inhibits Tubulointerstitial Lesion in a Murine Model of Lupus Nephritis.
Clopidogrel in a combined therapy with anticancer drugs-effect on tumor growth, metastasis, and treatment toxicity: Studies in animal models.
MiR-211 inhibits cell epithelial-mesenchymal transition by targeting MMP9 in gastric cancer.
Novel role of granulocyte-macrophage colony-stimulating factor: antitumor effects through inhibition of epithelial-to-mesenchymal transition in esophageal cancer.
TBL1XR1 predicts isolated tumor cells and micrometastasis in patients with TNM stage I/II colorectal cancer.
Elucidating Mechanisms of Bladder Repair after Hyaluronan Instillation in Ketamine-Induced Ulcerative Cystitis in Animal Model.
Long non-coding RNA NEAT1 regulates epithelial membrane protein 2 expression to repress nasopharyngeal carcinoma migration and irradiation-resistance through miR-101-3p as a competing endogenous RNA mechanism.
Overexpression of RCC2 Enhances Cell Motility and Promotes Tumor Metastasis in Lung Adenocarcinoma by Inducing Epithelial-Mesenchymal Transition.
In vitro anticancer activities of osthole against renal cell carcinoma cells.
Alterted SLIT2/ROBO1 signalling is linked to impaired placentation of missed and threatened miscarriage in early pregnancy.
E‑cadherin involvement in human lens epithelial cell transdifferentiation may be associated with N‑cadherin.
Macrophage migration inhibitory factor promotes vasculogenic mimicry formation induced by hypoxia via CXCR4/AKT/EMT pathway in human glioblastoma cells.
LncRNAAC132217.4, a KLF8-regulated long non-coding RNA, facilitates oral squamous cell carcinoma metastasis by upregulating IGF2 expression.
β-defensin 1 expression in HCV infected liver/liver cancer: an important role in protecting HCV progression and liver cancer development.
MicroRNA-23a promotes pancreatic cancer metastasis by targeting epithelial splicing regulator protein 1.
Single factors alone can induce mesenchymal-like morphology, but not promote full EMT in breast cancer cell lines with different hormone statuses.
Administration of alpha-ketoglutarate improves epithelial restitution under stress injury in early-weaning piglets.
Extracts of Zuo Jin Wan, a traditional Chinese medicine, phenocopies 5-HTR1D antagonist in attenuating Wnt/β-catenin signaling in colorectal cancer cells.
Protein tyrosine phosphatase receptor-type δ acts as a negative regulator suppressing breast cancer.
The mechanism of epithelial-mesenchymal transition induced by TGF-β1 in neuroblastoma cells.
Downregulation of miR-218 contributes to epithelial-mesenchymal transition and tumor metastasis in lung cancer by targeting Slug/ZEB2 signaling.
Calmodulin promotes matrix metalloproteinase 9 production and cell migration by inhibiting the ubiquitination and degradation of TBC1D3 oncoprotein in human breast cancer cells.
NID1, a new regulator of EMT required for metastasis and chemoresistance of ovarian cancer cells.
APC(Cdh1) controls cell cycle entry during liver regeneration.
Down-regulation of KIAA1199/CEMIP by miR-216a suppresses tumor invasion and metastasis in colorectal cancer.
Osthole inhibits the tumorigenesis of hepatocellular carcinoma cells.
The effects of 1,4-dimethylpyridine in metastatic prostate cancer in mice.
Transducin (β)-like 1 X-linked receptor 1 promotes gastric cancer progression via the ERK1/2 pathway.
IL-6 secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathway.
Correlations between TBL1XR1 and recurrence of colorectal cancer.
NUBPL, a novel metastasis-related gene, promotes colorectal carcinoma cell motility by inducing epithelial-mesenchymal transition.
Hypoxia-induced PLOD2 promotes proliferation, migration and invasion via PI3K/Akt signaling in glioma.
Curcumin increases efficiency of γ-irradiation in gliomas by inhibiting Hedgehog signaling pathway.
STIM1 and STIM2 differently regulate endogenous Ca(2+) entry and promote TGF-β-induced EMT in breast cancer cells.
MTA1 promotes epithelial to mesenchymal transition and metastasis in non-small-cell lung cancer.
Qi-Zhu-Xie-Zhuo-Fang reduces serum uric acid levels and ameliorates renal fibrosis in hyperuricemic nephropathy rats.
Self-renewing Monolayer of Primary Colonic or Rectal Epithelial Cells.
Transforming growth factor-β1 contributes to oxaliplatin resistance in colorectal cancer via epithelial to mesenchymal transition.
Long non-coding RNA UCA1 promotes gallbladder cancer progression by epigenetically repressing p21 and E-cadherin expression.
Linc-DYNC2H1-4 promotes EMT and CSC phenotypes by acting as a sponge of miR-145 in pancreatic cancer cells.
Autophagy plays a role in FSTL1-induced epithelial mesenchymal transition and airway remodeling in asthma.
Downregulation of Bmi-1 suppresses epithelial‑mesenchymal transition in melanoma.
CAPZA1 modulates EMT by regulating actin cytoskeleton remodelling in hepatocellular carcinoma.
High-mobility group box 1 is overexpressed in cervical carcinoma and promotes cell invasion and migration in vitro.
Epithelial-to-Mesenchymal Transition in Paclitaxel-Resistant Ovarian Cancer Cells Is Downregulated by Luteolin.
Long non-coding RNA AK058003, as a precursor of miR-15a, interacts with HuR to inhibit the expression of γ-synuclein in hepatocellular carcinoma cells.
Sinomenine hydrochloride attenuates the proliferation, migration, invasiveness, angiogenesis and epithelial-mesenchymal transition of clear-cell renal cell carcinoma cells via targeting Smad in vitro.
miR-200b-containing microvesicles attenuate experimental colitis associated intestinal fibrosis by inhibiting epithelial-mesenchymal transition.
Inversed Expression Patterns of S100A4 and E-Cadherin in Cervical Cancers: Implication in Epithelial-Mesenchymal Transition.
Interaction network of coexpressed mRNA, miRNA, and lncRNA activated by TGF‑β1 regulates EMT in human pulmonary epithelial cell.
Mastl overexpression is associated with epithelial to mesenchymal transition and predicts a poor clinical outcome in gastric cancer.
Disruption of the c-Myc/miR-200b-3p/PRDX2 regulatory loop enhances tumor metastasis and chemotherapeutic resistance in colorectal cancer.
Ethanol extract of gardenia fruit alleviates renal interstitial fibrosis induced by unilateral ureteral obstruction in rats.
SLC39A4 expression is associated with enhanced cell migration, cisplatin resistance, and poor survival in non-small cell lung cancer.
Metformin reverses prostate cancer resistance to enzalutamide by targeting TGF-β1/STAT3 axis-regulated EMT.
β-elemene inhibits tumor-promoting effect of M2 macrophages in lung cancer.
IL-6 promotes epithelial-to-mesenchymal transition of human peritoneal mesothelial cells possibly through the JAK2/STAT3 signaling pathway.
Atrial natriuretic peptide: A novel mediator for TGF-β1-induced epithelial-mesenchymal transition in 16HBE-14o and A549 cells.
Long non-coding RNA TUG1 promotes cell proliferation and metastasis by negatively regulating miR-300 in gallbladder carcinoma.
The role of metastasis-associated in colon cancer 1 (MACC1) in endometrial carcinoma tumorigenesis and progression.
Adipose-derived mesenchymal stem cells promote osteosarcoma proliferation and metastasis by activating the STAT3 pathway.
Mammalian Eps15 homology domain 1 promotes metastasis in non-small cell lung cancer by inducing epithelial-mesenchymal transition.
microRNA-802 inhibits epithelial-mesenchymal transition through targeting flotillin-2 in human prostate cancer.
Gas6/Axl Axis Contributes to Chemoresistance and Metastasis in Breast Cancer through Akt/GSK-3β/β-catenin Signaling.
Radiation promotes epithelial-to-mesenchymal transition and invasion of pancreatic cancer cell by activating carcinoma-associated fibroblasts.
Elevated eukaryotic elongation factor 2 expression is involved in proliferation and invasion of lung squamous cell carcinoma.
Oral kanglaite injection (KLTI) attenuates the lung cancer-promoting effect of high-fat diet (HFD)-induced obesity.
MMP-14 and CD44 in Epithelial-to-Mesenchymal Transition (EMT) in ovarian cancer.
Effects of RECQ1 helicase silencing on non-small cell lung cancer cells.
Depletion of Dicer promotes epithelial ovarian cancer progression by elevating PDIA3 expression.
MicroRNA-106a regulates phosphatase and tensin homologue expression and promotes the proliferation and invasion of ovarian cancer cells.
Design and Construction of a Multi-Organ Microfluidic Chip Mimicking the in vivo Microenvironment of Lung Cancer Metastasis.
Hsp60 exerts a tumor suppressor function by inducing cell differentiation and inhibiting invasion in hepatocellular carcinoma.
Effect of PPM1H on malignant phenotype of human pancreatic cancer cells.
Tanshinone IIA attenuates epithelial-mesenchymal transition to inhibit the tracheal narrowing.
miR-200c regulates crizotinib-resistant ALK-positive lung cancer cells by reversing epithelial-mesenchymal transition via targeting ZEB1.
E-cadherin is important for cell differentiation during osteoclastogenesis.
PTEN Regulates Renal Extracellular Matrix Deposit via Increased CTGF in Diabetes Mellitus.
miR-542-3p suppresses invasion and metastasis by targeting the proto-oncogene serine/threonine protein kinase, PIM1, in melanoma.
Neddylation controls basal MKK7 kinase activity in breast cancer cells.
The SDF-1/CXCR4 chemokine axis in uveal melanoma cell proliferation and migration.
β-Carotene Induces Apoptosis in Human Esophageal Squamous Cell Carcinoma Cell Lines via the Cav-1/AKT/NF-κB Signaling Pathway.
The anti-metastatic effect of 8-MOP on hepatocellular carcinoma is potentiated by the down-regulation of bHLH transcription factor DEC1.
IL-27 inhibits the TGF-β1-induced epithelial-mesenchymal transition in alveolar epithelial cells.
Silencing stem cell factor attenuates stemness and inhibits migration of cancer stem cells derived from Lewis lung carcinoma cells.
The E545K mutation of PIK3CA promotes gallbladder carcinoma progression through enhanced binding to EGFR.
microRNA-374a suppresses colon cancer progression by directly reducing CCND1 to inactivate the PI3K/AKT pathway.
Conditional ablation of TGF-β signaling inhibits tumor progression and invasion in an induced mouse bladder cancer model.
Effect of astragalus injection on renal tubular epithelial transdifferentiation in type 2 diabetic mice.
1-methylnicotinamide and its structural analog 1,4-dimethylpyridine for the prevention of cancer metastasis.
Ginsenoside Rg3 inhibits epithelial-mesenchymal transition (EMT) and invasion of lung cancer by down-regulating FUT4.
Establishment of a highly metastatic buccal squamous cell carcinoma cell line from a Sprague-Dawley Rat.
APC/C(CDC20) and APC/C play pivotal roles in the process of embryonic development in Artemia sinica.
Disrupting MALAT1/miR-200c sponge decreases invasion and migration in endometrioid endometrial carcinoma.
Regulation of CD40 signaling in colon cancer cells and its implications in clinical tissues.
Activation of the FAK/PI3K pathway is crucial for AURKA-induced epithelial-mesenchymal transition in laryngeal cancer.
High extracellular pressure promotes gastric cancer cell adhesion, invasion, migration and suppresses gastric cancer cell differentiation.
Interplay between intergrin-linked kinase and ribonuclease inhibitor affects growth and metastasis of bladder cancer through signaling ILK pathways.
Gingerol Reverses the Cancer-Promoting Effect of Capsaicin by Increased TRPV1 Level in a Urethane-Induced Lung Carcinogenic Model.
DIXDC1 activates the Wnt signaling pathway and promotes gastric cancer cell invasion and metastasis.
Notch signaling induces epithelial-mesenchymal transition to promote invasion and metastasis in adenoid cystic carcinoma.
Overexpression of Long Non-Coding RNA ZXF2 Promotes Lung Adenocarcinoma Progression Through c-Myc Pathway.
FOXQ1 mediates the crosstalk between TGF-β and Wnt signaling pathways in the progression of colorectal cancer.
Cytoplasmic expression of pontin in renal cell carcinoma correlates with tumor invasion, metastasis and patients' survival.
miR-195 Inhibits EMT by Targeting FGF2 in Prostate Cancer Cells.
Elevated GAPDH expression is associated with the proliferation and invasion of lung and esophageal squamous cell carcinomas.
Nuclear transcription factor CDX2 inhibits gastric cancer‑cell growth and reverses epithelial‑to‑mesenchymal transition in vitro and in vivo.
Pygopus-2 promotes invasion and metastasis of hepatic carcinoma cell by decreasing E-cadherin expression.
MG53-mediated cell membrane repair protects against acute kidney injury.
miR-494 suppresses the progression of breast cancer in vitro by targeting CXCR4 through the Wnt/β-catenin signaling pathway.
Flotillin-2 promotes metastasis of nasopharyngeal carcinoma by activating NF-κB and PI3K/Akt3 signaling pathways.
Knockdown of glucose-regulated protein 78/binding immunoglobulin heavy chain protein expression by asymmetric small interfering RNA induces apoptosis in prostate cancer cells and attenuates migratory capability.
The natural compound celastrol inhibits necroptosis and alleviates ulcerative colitis in mice.
Anti-pulmonary fibrotic activity of salvianolic acid B was screened by a novel method based on the cyto-biophysical properties.
Truncating mutation in the autophagy gene UVRAG confers oncogenic properties and chemosensitivity in colorectal cancers.
Ketamine-induced ulcerative cystitis and bladder apoptosis involve oxidative stress mediated by mitochondria and the endoplasmic reticulum.
DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway.
Aberrant expression of the autocrine motility factor receptor correlates with poor prognosis and promotes metastasis in gastric carcinoma.
BioPen: direct writing of functional materials at the point of care.
TGF-β2 induces transdifferentiation and fibrosis in human lens epithelial cells via regulating gremlin and CTGF.
Effects and mechanism of dehydroepiandrosterone on epithelial-mesenchymal transition in bronchial epithelial cells.
Impact of Mucin1 knockdown on the phenotypic characteristics of the human hepatocellular carcinoma cell line SMMC-7721.
Osteogenic differentiation of human amniotic epithelial cells and its application in alveolar defect restoration.
Increased expression levels of E-cadherin, cytokeratin 18 and 19 observed in preeclampsia were not correlated with disease severity.
Vascular endothelial growth factor receptor-1 activation promotes migration and invasion of breast cancer cells through epithelial-mesenchymal transition.
HMGA2 elicits EMT by activating the Wnt/β-catenin pathway in gastric cancer.
Inhibition of cell migration by ouabain in the A549 human lung cancer cell line.
Tumor associated macrophage × cancer cell hybrids may acquire cancer stem cell properties in breast cancer.
Caveolin-1 knockdown is associated with the metastasis and proliferation of human lung cancer cell line NCI-H460.
Identification of human host proteins contributing to H5N1 influenza virus propagation by membrane proteomics.
Response gene to complement-32 enhances metastatic phenotype by mediating transforming growth factor beta-induced epithelial-mesenchymal transition in human pancreatic cancer cell line BxPC-3.
Brain-selective kinase 2 (BRSK2) phosphorylation on PCTAIRE1 negatively regulates glucose-stimulated insulin secretion in pancreatic β-cells.
Jiang Z, Ye X, Song M, Qiao Y, Cheng W, Wang D, Zhang X, Li X, Yu X, Wang X, Ji J, Mou Y
Nucleosides, nucleotides & nucleic acids 2026;45(1):64-87
Nucleosides, nucleotides & nucleic acids 2026;45(1):64-87
Versatile Nanotherapeutics for Enhancing Sonodynamic Therapy/Chemotherapy of Thyroid Cancer through Remodeling Tumor Microenvironment and Synergistic Reactive Oxygen Species Augment.
Wang D, Sun L, Wang J, Wang L, Wang Z, Zhang Y, Zhou Q, Chen Y, Jiang J
Biomaterials research 2026;30:0338
Biomaterials research 2026;30:0338
THBS3 Functions as a Novel Biomarker for Prognosis and Immunotherapeutic Response in Colorectal Cancer: An Integrative Analysis and Validation of the Thrombospondin Gene Family.
Jiang T, Zhu S, Zhou H, Zhang N, Zhang L, Zou C, Song H
Cancer informatics 2026;25:11769351251412614
Cancer informatics 2026;25:11769351251412614
Co-targeting MRPS7-23 synergistically enhances cisplatin efficacy to suppress nasopharyngeal carcinoma growth and metastasis.
Cao Z, Pan C, Liu Z, Quan Q, Li M, Huang Y, Liang C, Chen Y, Fan T, Chen P, Kai F, Zhu S, Li S, Su X, Wang F, Fu L, Zhang B
International journal of biological sciences 2026;22(2):970-994
International journal of biological sciences 2026;22(2):970-994
LncRNA VCAN-AS1 Sponges miR-374c-3p to Promote Proliferation, Invasion, Migration, and EMT in Thyroid Cancer.
Zhang Y, Sun L, Wu Y, Liu Y, Jiang H, Chen X, Wang L, Wu C
International journal of endocrinology 2026;2026:8809262
International journal of endocrinology 2026;2026:8809262
Yifei Decoction Regulates the NGF/TRKA/PI3K/AKT Signaling Axis to Inhibit the Epithelial-Mesenchymal Transformation and Proliferation of Pulmonary Epithelial Cells in Bleomycin-Induced Pulmonary Fibrogenesis.
Chen L, Lan C, Deng X, Wu M, Shao M, Yang M, Ma X, Huang F, Wu H
Canadian respiratory journal 2026;2026:6614209
Canadian respiratory journal 2026;2026:6614209
Tuft Cells in the Gut Limit Cognitive Disorders by Regulating Gut Homeostasis.
Chen L, Yang Y, Zhang Y, Yang X, Zhang X, Chen L, Li W, Zhang S, Xiong R, Wang J, Xu Z, Zhang ZY, Pan C, Ji M
Cellular and molecular gastroenterology and hepatology 2026;20(6):101747
Cellular and molecular gastroenterology and hepatology 2026;20(6):101747
Berberine Ameliorates Diabetic Kidney Disease by Modulating Macrophage Polarization via Inhibiting IL-17A Signaling.
Fan J, Liu Y, Zheng C, Liu J, Liu W, Geng R, Zhao A, Wang Y, Wang R, Qi Z
Journal of inflammation research 2026;19:580534
Journal of inflammation research 2026;19:580534
GNPAT promotes immunosuppression in hepatocellular carcinoma by activating the plasmalogen-PPARγ pathway to drive M2 macrophage polarization.
Hu M, Zhang N, Wang YQ, Wang XM, Shi Y, Yao M, Hou LG, Jiang LL
Frontiers in immunology 2026;17:1765930
Frontiers in immunology 2026;17:1765930
The prognostic significance of JAML and its role in remodeling the immune microenvironment via the cGAS-STING pathway in endometrial cancer.
Tian C, Yao Y, Tu Y, Yu J, Gong C, Shi X, Yu H, Jiang P
Frontiers in immunology 2026;17:1738596
Frontiers in immunology 2026;17:1738596
Targeting CPS1 attenuates lung cancer metastasis by regulating EMT through an epigenetic mechanism.
Ding Y, Tian Y, Li M, Fu Y, Wang T, Du X, Wang M, Dong L, Gao F, Liu B, Lu Y, Zhang C, Mao L, Jiang J, Li L, Liao L, Li K
Theranostics 2026;16(4):1740-1761
Theranostics 2026;16(4):1740-1761
A novel mouse cell line model reveals the tumor intrinsic and immune characteristics of EGFR-mutant lung cancer.
Yan Y, Shang J, Liu C, Chen Y, Bao Y, Zhao Y, Fan F, Sun Y, Zhou Y, Wu Y, Wang Y, Han H, Chen H, Pan Y
Theranostics 2026;16(2):1006-1022
Theranostics 2026;16(2):1006-1022
Macrophage-Derived Transcriptional Signatures Predict Prognosis and Drug Sensitivity in Thyroid Cancer: Integrative Analysis and Experimental Validation of SMYD3.
Xu S, Zhang X, Sun J, Qin M, Du H, Luo B
ImmunoTargets and therapy 2026;15:565624
ImmunoTargets and therapy 2026;15:565624
Hydroxysafflor Yellow A improves diabetic nephropathy by inhibiting PI3K/AKT/mTOR pathway based on a multidimensional study.
Liu J, Gao J, Jiang Z, Li W, Zhang P, Liu X, Lyu B
Frontiers in medicine 2026;13:1747346
Frontiers in medicine 2026;13:1747346
Endothelial SMAD1-MCAM axis facilitates sunitinib resistance and progression of clear cell renal cell carcinoma via LAMB1-ITGB1 signaling.
Zhang H, Liu Y, Zhang W, Guo Y, Lin A, Jin Y, Lu P, Fang Y, Zhang H, Qu L, Luo P, Wu L, Chen Y, Kang X, Wang L, Jiang A
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 May;86:101388
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 May;86:101388
ATP-binding cassette subfamily A member 5 suppresses pancreatic ductal adenocarcinoma progression and chemoresistance by promoting β-catenin ubiquitin-dependent degradation.
Li Z, Ma Z, Chen Y, Yu W, Yu J, Lu J, Zhang Q, Wu Q, Cai Y, Wang Z, Shang C, Hou B, Zhang C, Huang S, Wang L, Zhou Q
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 May;86:101381
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 May;86:101381
RNA‑binding protein DAZAP1 promotes gastric cancer metastasis by enhancing NOTCH1 and JAG1 mRNA stability.
Peng S, Chen Y, Wu J, Huang X, Hong L, Xie Y, Lei Y, Wei X, Yang P, Zhang J, Yang Q, Liu G, Li A, Liu S, Li J, Dai W, Hu Y, Wang J, Xiong J, Wang J
International journal of oncology 2026 May;68(5)
International journal of oncology 2026 May;68(5)
PLOD2 Promotes Cutaneous Squamous Cell Carcinoma Progression in Association With STAT3-Related ERK and AKT Pathways.
Xian N, Wang Z, Wang B, Wang X, Zheng Y
Molecular carcinogenesis 2026 May;65(5):615-629
Molecular carcinogenesis 2026 May;65(5):615-629
Plasmin promotes hepatocellular carcinoma invasion and metastasis via CXCR4-mediated activation of PI3K/AKT/mTOR signaling.
Shen Z, Yang Y, Mao T, Wu F, Li F, Yang L, Yu M, Zhao B
Oncogene 2026 May;45(19):1815-1827
Oncogene 2026 May;45(19):1815-1827
Development of a self-assembling aggregation-induced emission nanoprobe for targeted therapy and real-time imaging in non-small cell lung cancer.
Ren Z, Li S, Cui T, Zhu T, Ding D, Zhao J, Yuan H
Journal of photochemistry and photobiology. B, Biology 2026 May;278:113402
Journal of photochemistry and photobiology. B, Biology 2026 May;278:113402
Differences in palatal shelf epithelial stiffness between the lingual/nasal and buccal/oral surfaces during palatal shelf elevation in developing mice.
Nagasaka A, Bando Y, Toda-Fujii M, Onozawa G, Suzuki K, Miyata T, Amano O
Developmental dynamics : an official publication of the American Association of Anatomists 2026 May;255(5):464-474
Developmental dynamics : an official publication of the American Association of Anatomists 2026 May;255(5):464-474
Peroxiredoxin 4 suppresses ferroptosis in esophageal squamous cell carcinoma by activating the phosphoinositide 3-kinase signaling pathway.
Li K, Xu S, Liu H, Fan T, Li Y, Ren R, Xu Y, Li S, Liu Y
Biomedical reports 2026 May;24(5):60
Biomedical reports 2026 May;24(5):60
m⁶A-modified circMELK regulates nasopharyngeal carcinoma progression via a YTHDF1/circMELK-miR-4775-HMGA2 feedback loop.
Yi Q, Zhong K, Chen Z, Ouyang X, Zhu W, Liang L, Zhong J
Molecular immunology 2026 May;193:50-67
Molecular immunology 2026 May;193:50-67
Bufei Jianspi formula alleviates intestinal epithelial barrier injury by inhibition of calpain 2 in COPD rat.
Wang K, Tao L, Zhang Q, Liu L, Shan B, Zhao P, Li J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158006
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158006
Study on the anti-pulmonary fibrosis mechanism of Renshen Pingfei formula by inhibiting M2 macrophage polarization and regulating TGF - β/SMAD signaling pathway.
Hong L, Sun Y, Hou H, Zhang J, Shi W, Yang Y, Fan X, Zhu J
Journal of ethnopharmacology 2026 May 23;363:121465
Journal of ethnopharmacology 2026 May 23;363:121465
Prenylterphenyllin, a regulator of P53, inhibits colorectal cancer progression through oxidative stress and energy metabolism pathway.
Zhang Y, Han Y, Li S, Shan R, Lin L, Gu Z, Wang R, Chen Y, Xiao J, An F, Hu C, He C
Redox biology 2026 Mar;90:103993
Redox biology 2026 Mar;90:103993
ENO1 inhibition synergizes with chidamide to induce ferroptosis in PTCL-NOS through metabolic remodeling.
Zhu F, Tian M, Lu K, Wang C, Liu J, Li X, Gu X, Lv B, Huang Z, Zeng L, Li Z, Lu H, Xu K
Blood science (Baltimore, Md.) 2026 Mar;8(1):e00272
Blood science (Baltimore, Md.) 2026 Mar;8(1):e00272
Oncogenic role of talin-1 in glioma: Association with poor prognosis and regulation of the TGF-beta signaling pathway.
Li J, Zhang D, Zhou H, Hou L, Wang Y, Zhang Z, Wang Y, Li X, Yi L, Liu X, Wang Y, Xue X
Translational oncology 2026 Mar;65:102691
Translational oncology 2026 Mar;65:102691
Natural compound 5,7,8‑trimethoxyflavone mitigates radiation‑induced lung injury by suppressing EMT and PI3K/Akt pathway.
Gong CC, Li HK, Mi YZ, Chen JY, Fang ZY, Fu SL, Quan L, Lin B, Lang JY, Chen Q, Xu K, Chen MH
International journal of molecular medicine 2026 Mar;57(3)
International journal of molecular medicine 2026 Mar;57(3)
Homoharringtonine inhibits growth and migration in non-small cell lung cancer via PDIA4-mediated modulation of autophagy and EMT.
Ma X, Lei P, Ren B, Xie S, Zhang Y, Wang Y, Ma W
Archives of pharmacal research 2026 Mar;49(3):357-374
Archives of pharmacal research 2026 Mar;49(3):357-374
Promotion of hepatocellular carcinoma by small nuclear ribonucleoprotein polypeptide F through upregulation of transmembrane P24 trafficking protein 2 and triggering of the cGAS-STING pathway.
Xie X, Pu L, Zeng J, Xu M, Yin X, Liu H, Yang J, Cao J, Song H
International journal of biological macromolecules 2026 Mar;352:151166
International journal of biological macromolecules 2026 Mar;352:151166
Novel nanoparticle-combined therapy through EGFR and PD-L1 blockade: PFPR-siRNA-mediated suppressing NSCLC proliferation via PDT and enhanced antitumor immunity.
Zhang M, Xie N, Wu D, Wu C, Guo Y, Wang N, Li XY, Liang Y, Xie X, Wang T, Li YJ, Ning F, Wang RR, Xie SY, Wang PY
Colloids and surfaces. B, Biointerfaces 2026 Mar;259:115284
Colloids and surfaces. B, Biointerfaces 2026 Mar;259:115284
Astaxanthin alleviates DSS-induced ulcerative colitis in mice associated with Nrf2-mediated ferroptosis independently of gut microbiota modulation.
Wei MX, Wu XY, Lin JW, Huang JY, Cheng J, Huang WF, Xu GH, Yi LT
The Journal of nutritional biochemistry 2026 Mar;149:110212
The Journal of nutritional biochemistry 2026 Mar;149:110212
TRIM35 inhibits endometrial cancer progression via ubiquitination and degradation of EIF3E.
Wang Q, Ning N, Li Y
Cellular signalling 2026 Mar;139:112339
Cellular signalling 2026 Mar;139:112339
UBR5 regulates the progression of colorectal cancer cells through Snail-induced epithelial-mesenchymal transition.
Zhao X, Liu R, Han Z, Li Z, Mei L, Liu Y, Fu X, Jin Y
Genes & diseases 2026 Mar;13(2):101679
Genes & diseases 2026 Mar;13(2):101679
ANO6 Confers Paclitaxel Resistance by Targeting Ferroptosis in Cervical Cancer.
Cao Y, Peng Y, Shen J
BioFactors (Oxford, England) 2026 Mar-Apr;52(2):e70070
BioFactors (Oxford, England) 2026 Mar-Apr;52(2):e70070
An integrated network pharmacology and proteomics approach reveals the anti-fibrotic effect of Fushen Granule on peritoneal fibrosis.
Yang K, Li J, Wang L, Yu H, Liu X, Gao Z, Wang Z, Zhang L, Yang H
BMC complementary medicine and therapies 2026 Mar 9;26(1)
BMC complementary medicine and therapies 2026 Mar 9;26(1)
PIEZO1 enhances pancreatic cancer neurotropism.
Li J, Liu Q, Xu R, Tang J, Wang L, Zheng Y, Weng S, Gao F
Cancer cell international 2026 Mar 9;26(1)
Cancer cell international 2026 Mar 9;26(1)
WISP2 Overexpression Is Associated with Reduced Vasculogenic Mimicry and Epithelial-Mesenchymal Transition in Gastric Cancer.
Xu X, Chen Y, Zhang L, Pan P, Duan T, Cheng Z, Lu G
Digestive diseases and sciences 2026 Mar 8;
Digestive diseases and sciences 2026 Mar 8;
AI-enabled single-cell dissection of the palmitoylation landscape identifies a multicellular prognostic program in gastric cancer.
Xu J, Hu Y, Qiao Q, Lu Y, Cen F, Hou S, Yang H, Lv J, Qin Y, Xia S
NPJ precision oncology 2026 Mar 7;10(1)
NPJ precision oncology 2026 Mar 7;10(1)
Kukoamine B Inhibits EMT in Lung Adenocarcinoma Cells by Regulating Intracellular PD-L1-Mediated p65 Nuclear Translocation.
Hou C, Chen J, Zhang L, Huang Q, Xu J, Zhang R, He Y
Biology 2026 Mar 6;15(5)
Biology 2026 Mar 6;15(5)
Activation of the PI3K/AKT pathway by EDIL3 induces EMT and promotes tumor progression in clear cell renal cell carcinoma.
Tao L, Xie W, Du Y, Zhang R
Molecular genetics and genomics : MGG 2026 Mar 4;301(1)
Molecular genetics and genomics : MGG 2026 Mar 4;301(1)
TFAP2A regulates SGPP2 transcription to promote lipid accumulation and activate the Wnt/β-catenin signaling pathway to promote malignant progression in lung adenocarcinoma.
Li Q, Li J, Zhang C, Deng Y, Yang B, Ma L, Liu Y, Wang C, Xu L, Mei J
Journal of translational medicine 2026 Mar 4;24(1)
Journal of translational medicine 2026 Mar 4;24(1)
Clonal Stabilization Reveals a DAO/3MST-Expressing MDCK Subpopulation With Robust d-Cysteine-Mediated H(2)S Production.
Miyamoto A, Ueno H, Kimura H, Nakagawa T, Shibuya N
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 31;40(6):e71699
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 31;40(6):e71699
BHMT Protects Against Diabetic Cataracts by Reducing Homocysteine and Counteracting Endoplasmic Reticulum Stress in Lens Epithelial Cells.
Zhou H, Zhu T, Xie S, Zhao Y, Wang Y, Qin J
Applied biochemistry and biotechnology 2026 Mar 30;
Applied biochemistry and biotechnology 2026 Mar 30;
lnc-ALX1-2:10 is a novel regulator that enhances proliferation, migration and invasion in prostate cancer cells.
Wang X, Zong Q, Bu Y, Zhou B, Wang X, Li Z, Luo G
Scientific reports 2026 Mar 3;16(1)
Scientific reports 2026 Mar 3;16(1)
Multi-omics analysis of NEDD1 in hepatocellular carcinoma: biological function, prognostic value, and clinical significance.
Chen Y, Wan Z, Xie H, Zhou X, Peng T
Scientific reports 2026 Mar 3;16(1)
Scientific reports 2026 Mar 3;16(1)
Perfluorocarbon ameliorates high-altitude pulmonary edema and blood-gas barrier dysfunction in a canine model and a lung-on-chip model by suppressing the HIF-1α/HO-1 pathway.
Zhang Z, Ma X, Su C, Meng J, Yu H, Liang Z, Xu Y, Zhu Q, Song Z, Chen L, Yang Z
European journal of pharmacology 2026 Mar 28;1019:178717
European journal of pharmacology 2026 Mar 28;1019:178717
Spiky Nanoparticle-Gel Composite for Efficient Intravesical Botulinum Toxin A Delivery and Treatment of Overactive Bladder.
Zhou Y, Liu Q, Wang L, Sun H, Liu Y, Xiang T, Zhu M, Liu X, Liu T, Cong H, Liao L
Advanced healthcare materials 2026 Mar 27;:e05843
Advanced healthcare materials 2026 Mar 27;:e05843
Mechanism of LPS-activated gingival fibroblasts promote the migration of gastric cancer cells via CXCL12/CXCR4-Snail2-EMT axis.
Liu T, Tang Q, Liu M, Ren F, Liu R
In vitro cellular & developmental biology. Animal 2026 Mar 26;
In vitro cellular & developmental biology. Animal 2026 Mar 26;
Mechanistic study of miR-486-5p targeting Claudin-10 in placenta accreta spectrum pathogenesis and its impact on trophoblast behavior.
Dong T, Jiang Y, Ye F, Zhao B, Xi F, Lv M, Yang M, Pu Y, Jiang P, Luo Q
Placenta 2026 Mar 25;176:76-86
Placenta 2026 Mar 25;176:76-86
Tannic Acid Inhibits Lung Adenocarcinoma Progression by Suppressing MMP-2-Mediated Epithelial-Mesenchymal Transition.
Lin M, Zhou Y, Wang Y, Yan H, Qin X, Zhong X, Yang G, Liu Q
Biochemical genetics 2026 Mar 25;
Biochemical genetics 2026 Mar 25;
Hydrogen sulfide ameliorates oxalate crystal-related renal injury via inhibiting the activation of NOD-like receptor thermal protein domain associated protein 3 inflammasome in mice.
Shi Y, Chen L, Li M, Wang J, Yin P, Zhou X, Cong Q, Song K
Urolithiasis 2026 Mar 24;54(1)
Urolithiasis 2026 Mar 24;54(1)
The APC/C subunit APC7 promotes hepatocellular carcinoma progression by mediating ubiquitination and degradation of LATS1 to activate YAP/TAZ.
Sun Y, Zhang R, Guo Y, Wu D, Wei H, Tan Z, Huang M, Wang Y, Fang Z, Zhang C, Li C, Li W, Wei D, Bian H, Liu ZK
Biology direct 2026 Mar 23;21(1)
Biology direct 2026 Mar 23;21(1)
Curculigoside attenuates influenza virus-induced acute lung injury by modulating the Keap1/Nrf2 signaling pathway.
Liu T, Chen F, Wu L, Zhang H, Yin P
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar 21;
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar 21;
USP1 promotes hepatocellular carcinoma progression by modulating mitophagy via stabilizing MCM3 to regulate the Keap1-Nrf2 axis.
Chen Z, Sun C, Wang Y, Duan X, Ma H, Zhou X, Chen S, Peng P
iScience 2026 Mar 20;29(3):114927
iScience 2026 Mar 20;29(3):114927
USP5-mediated CD73 deubiquitination drives osimertinib resistance via PI3K/AKT and glycolysis activation in LUAD.
Chen R, Han XH, Zhang Z, Han XJ, Xie J
iScience 2026 Mar 20;29(3):114916
iScience 2026 Mar 20;29(3):114916
SGK1 Is Upregulated in Retained Placenta and Mediates Estradiol Effects in Bovine Endometrial Cells.
Wang R, Wei M, Niu W, Chen J, Nan J, Zhang Y, Zhao X, Wang Q
Cells 2026 Mar 20;15(6)
Cells 2026 Mar 20;15(6)
FUT8 reprograms glycolytic metabolism to promote PKM2 lactylation and drive clear cell renal cell carcinoma progression.
Guo Z, Jiang H, Wang X, Xuan K, Zhong H, Liu C, Zhang M, Li Z, Huang W, Sun Y
Cell death discovery 2026 Mar 19;12(1)
Cell death discovery 2026 Mar 19;12(1)
B3GNT3 facilitates NFKB2 processing and non-canonical NF-κB activation to drive lung adenocarcinoma progression.
Lin Y, Zhang Y, Yu B, Wang J, Wu Z, Wang H
Cellular oncology (Dordrecht, Netherlands) 2026 Mar 16;49(2)
Cellular oncology (Dordrecht, Netherlands) 2026 Mar 16;49(2)
Far Infrared Radiation Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice via Modulation of the p53/TGF-β Signaling Pathway.
Li J, Chang J, Chu W, Jiang Y, Sun S, Ding X, Zhang L, Shi L
International journal of molecular sciences 2026 Mar 10;27(6)
International journal of molecular sciences 2026 Mar 10;27(6)
Highly Ca(2+)-permeable transient receptor potential vanilloid 6 contributes to the protection against colitis by regulating epithelial barrier function.
Murayama Y, Yasuda H, Saito M, Hayashi S, Matsumoto K, Kato S
American journal of physiology. Gastrointestinal and liver physiology 2026 Mar 1;330(3):G302-G313
American journal of physiology. Gastrointestinal and liver physiology 2026 Mar 1;330(3):G302-G313
RRP9 suppresses hepatocellular carcinoma progression by inhibiting the PI3K/AKT/mTOR pathway.
Fu Z, Li M, Dong K, Feng J, Wang W
International journal of oncology 2026 Jun;68(6)
International journal of oncology 2026 Jun;68(6)
Mechanism of HAND2 Regulating Glycolytic Metabolism and Metastasis Through TLR4/NOX2/DUOX2 Signaling Axis in Cervical Cancer.
Yang H, Li Y, Xiao Z, Kuang M
Molecular carcinogenesis 2026 Jun;65(6):699-714
Molecular carcinogenesis 2026 Jun;65(6):699-714
Phosphoethanolamine cytidylyltransferase 2 exerts an anti-tumor role in clear cell renal cell carcinoma by modulating the hippo/YAP1 signaling pathway in a PPP2R1A-dependent manner.
Nan N, Guo H, Huang Y, Chen J, Qiang X
Toxicology and applied pharmacology 2026 Jun;511:117786
Toxicology and applied pharmacology 2026 Jun;511:117786
Mechanical cues regulate in vitro implantation of mouse embryos.
Liu Q, Chen K, Pan S, Zhang T, Wang Q, Zhu J, Zhang J, Jiang X, Jia H, Zheng S, Luo T
Materials today. Bio 2026 Jun;38:103105
Materials today. Bio 2026 Jun;38:103105
Overexpression and knockdown of 5-lipoxygenase regulates the migration and invasion of colorectal cancer cells.
Li X, Huge J, Wang X, Zhou J, Li X, Gao X, Shi T, Bai C
Oncology letters 2026 Jun;31(6):221
Oncology letters 2026 Jun;31(6):221
cGAS-STING signaling pathway promotes ischemic kidney injury by regulating HK3-mediated lipid accumulation.
Wang D, Zhou Z, Zhao Z, Liu M, Li Y, Mu L, Zhou H, Li X, Zhang F, Tian S, Zhou X, Shi Y
Free radical biology & medicine 2026 Jun;249:246-259
Free radical biology & medicine 2026 Jun;249:246-259
MEHP promotes breast cancer progression via GPR30-mediated epithelial-mesenchymal transition.
Qi W, Wang J, Wang Y, Cui J, Wu X, Ding Z, Jiang T, Liu W, Zhai X, Jin S, Ye L
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 Jun;212:116049
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2026 Jun;212:116049
Inhibition of GRK2 mitigates cisplatin-induced acute and chronic nephrotoxicity by targeting the NADPH oxidase 4/oxidative stress axis.
Duan F, Ni L, Wang Q, Peng J, Wang X, Wang Y, Hu S, Kuai J, Jiang X, Wang Q, Xu B, Wei W, Wang C
British journal of pharmacology 2026 Jun;183(12):3149-3172
British journal of pharmacology 2026 Jun;183(12):3149-3172
HOMER3 as a prognostic and immune-related biomarker in pan-cancer and esophageal carcinoma: Insights from bioinformatics and functional validation.
Su ZP, Yang N, Cui BQ, Li ZQ, Feng HM, Zhai KR, Ren MY, Chen YZ, Li B
Cellular signalling 2026 Jun;142:112424
Cellular signalling 2026 Jun;142:112424
The role of FPR3 in remodeling the immune microenvironment and lung metastasis of colon adenocarcinoma.
Xu N, Xia T, Wu M, Ye F, Zhao W, Zhao M, Mao Y, Ge Y, Du J
Cellular signalling 2026 Jun;142:112420
Cellular signalling 2026 Jun;142:112420
Therapeutic mechanism of Changyong Decoction in suppressing colorectal cancer progression and inducing ferroptosis via the PIEZO1-PI3K/AKT signaling axis.
Han M, Shi S, Guan Z, Ma W, Wang X, Jiang H, Man S
Tissue & cell 2026 Jun;100:103379
Tissue & cell 2026 Jun;100:103379
Syntaphilin inhibits glioma invasion via modulating mitochondria redistribution and shapes the immune microenvironment: A potential prognostic biomarker.
Tian H, Chen X, Si M, Xu W
Gene 2026 Jun 5;993:150105
Gene 2026 Jun 5;993:150105
Comprehensive S-acylation profiling of the porcine epididymis and exosomes reveals a role in cargo sorting and long-distance trafficking.
Cao H, Liu X, Li L, Liu S, Gao H, Dong Q, Nie H, Li Y, Gong Y, Jin T, Wang Y, Qin W, Dong W
Journal of proteomics 2026 Jun 15;328:105645
Journal of proteomics 2026 Jun 15;328:105645
Immune-epithelial dual-targeting bilirubin nanoparticles for acute lung injury.
Tang Y, Xu Y, Ye J, Han Y, Zhang M, Sun Y, Kang Y, Zhu S, Cai L, Wu R, Gong W, Yao Q, Duan B, Kou L, Chen R, Zhang H
Journal of controlled release : official journal of the Controlled Release Society 2026 Jun 10;394:114852
Journal of controlled release : official journal of the Controlled Release Society 2026 Jun 10;394:114852
IGHG1(+) malignant epithelial Cell-myCAF crosstalk via MIF-CD74/APP-CD74 drives early brain metastasis in NSCLC: Delineated via primary tumor-brain metastasis single-cell and spatial transcriptomics.
Yang L, Yang H, Zhao M, Wen Y, Wu L, Chen Q, Cao F, Zhao Y, Ye D, Yuan M, Yu J, Sun X, Xing L
Cancer letters 2026 Jun 1;647:218451
Cancer letters 2026 Jun 1;647:218451
Hyaluronic acid-based reactive oxygen species responsive nanocomposite hydrogel for sequential drug delivery and effective prevention of postoperative abdominal adhesions.
Gong Y, Xiao D, Zhang T, Shi X, Wang S, Huang Y, Zhao C
Carbohydrate polymers 2026 Jun 1;381:125148
Carbohydrate polymers 2026 Jun 1;381:125148
A positive SPTBN2-FLI1 feedback axis promotes bladder cancer via PI3K/AKT activation.
Guo X, Zhu C, Yin Z
Cellular signalling 2026 Jul;143:112471
Cellular signalling 2026 Jul;143:112471
Targeting the NR5A1-KISS1R-EMT axis with a small-molecule inhibitor suppresses lung adenocarcinoma progression and metastasis.
Wang D, Hui K, Yuan C, Lan W, Liu L, Yu Z, Li X, Shen X, Liu B, Jiang X
Cellular signalling 2026 Jul;143:112453
Cellular signalling 2026 Jul;143:112453
Identification of PLXNC1 as a novel biomarker for consensus molecular subtype 4 in colorectal cancer.
Wang W, Zhou M, Li T, Gan W, Lv S, Yan Z, Hou Y, Zeng Z, Yang L, Zhang F, Zhao W, Yang M
Genes & diseases 2026 Jul;13(4):101974
Genes & diseases 2026 Jul;13(4):101974
GLT8D2-mediated PD-L1 N-glycosylation promotes tumor immune evasion in ovarian cancer peritoneal metastasis.
Xu Y, Huang S, Chen J, Tang Z, Fu Y, Chen Z, Lin Z, Hu J, Zhang W, He S
Cancer letters 2026 Jul 10;650:218478
Cancer letters 2026 Jul 10;650:218478
Transmembrane Protein TMEM59L Modulates 5-FU Resistance via PTPRN-Mediated DNA Damage Repair in Colorectal Cancer.
Jin W, Ma Q, Ma Z, Hou J, Wang F, Kang H, Wang C, Wang X, Liu F
Cancer reports (Hoboken, N.J.) 2026 Jan;9(1):e70448
Cancer reports (Hoboken, N.J.) 2026 Jan;9(1):e70448
Metformin attenuates colitis via blocking STAT3 acetylation by reducing acetyl-CoA production.
Li X, Xiang Z, Wang X, He H, Xu M, Tan C, Wu X, Zhang J, Dong W
Journal of advanced research 2026 Jan;79:393-407
Journal of advanced research 2026 Jan;79:393-407
Basement membrane-associated gene P3H2 regulates osteosarcoma progression and epithelial-mesenchymal transition through AKT/mTOR signaling axis.
Pan R, Zhang Y, Wang H, Guan J, Chen Z, Xiao L, Ru N, Zhao J, Cheng Y, Feng S, Zheng X
Translational oncology 2026 Jan;63:102569
Translational oncology 2026 Jan;63:102569
Narirutin Reprograms Fatty Acid Metabolism and Inhibits Tumorigenesis via Downregulating ADORA3 Expression in Colorectal Cancer.
Wang H, Jiang R, Liu C, Chen F
Journal of gastroenterology and hepatology 2026 Jan;41(1):202-214
Journal of gastroenterology and hepatology 2026 Jan;41(1):202-214
Bacterial cellulose repairs asthmatic epithelial injury by reprogramming CDS1-mediated phosphatidylinositol metabolism to inhibit PI3K/AKT signaling.
Yu Q, Huang L, Wu Z, Zhuo J, Huang H, Cheng Y, Hu M, Wang Q, Liu D, Jiang X, Zhang J, Cai S, Dong H
International journal of biological macromolecules 2026 Jan;338(Pt 2):149695
International journal of biological macromolecules 2026 Jan;338(Pt 2):149695
TRIM32 promotes anoikis resistance and metastasis in NSCLC by degrading CHEK2 to enhance IL-6 secretion.
Xu J, Liu W, Chen L, Zhang J, Zhang D, Huang X, Zhang G
Cell death and differentiation 2026 Jan;33(1):126-139
Cell death and differentiation 2026 Jan;33(1):126-139
Downregulation of BST2 Rescues Cochlear Nerve Demyelination in Age-Related Hearing Loss via Enhancing Schwann Cell Migration.
Liu M, Li Q, Cao H, Yin H, Yang J, Liu T, Wang J, Zhao L, Wang B
Aging cell 2026 Jan;25(1):e70325
Aging cell 2026 Jan;25(1):e70325
Silence of circPLK1 inhibits NSCLC progression by regulating the miR-1294/SLC16A9 axis.
Li C, Yang Y, Li Q, Wang G, Tao T, Li L, Sang H
Molecular immunology 2026 Jan;189:216-225
Molecular immunology 2026 Jan;189:216-225
Unraveling the active ingredients and molecular mechanisms of Qinghua Changyan granule against irritable bowel syndrome with diarrhea: Effects on gut microbiota and glutamine transport via an integrative approach combining UHPLC-MS/MS and experimental verification.
Yang J, Wang Y, Wang S, Liu Z, Chen X, Jia R, Wang J, Wang F, Yang Q, Tang L, Miao W
Fitoterapia 2026 Jan;188:106960
Fitoterapia 2026 Jan;188:106960
CypA Mediates Non-Small Cell Lung Cancer Chemoresistance by Attenuating Ferroptosis via Stabilizing SLC7A11.
Wang Z, Li A, Song Z, Liu X, Ge Y, Chen Z, Liu Y, Zhang B, Zhang H, Lan T
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(4):e11947
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(4):e11947
SIGLEC15 modulates the immunosuppressive microenvironment and suppresses malignant phenotypes in triple-negative breast cancer.
Tan Z, Xin H, Chen J, Lei M, Tu G, Tang L
Genes & diseases 2026 Jan;13(1):101799
Genes & diseases 2026 Jan;13(1):101799
Membrane potential mediates the cellular response to mechanical pressure.
Mukherjee A, Huang Y, Elgeti J, Oh S, Abreu JG, Ammar L, Neliat AR, Schüttler J, Su DD, Dupre C, Benites NC, Liu X, Peshkin L, Barboiu M, Stocker H, Kirschner MW, Basan M
Cell 2026 Jan 8;189(1):143-160.e22
Cell 2026 Jan 8;189(1):143-160.e22
NAT10-mediated ac4C modifications regulate glioblastoma progression.
Lin L, Xiong Y, Guo Y, Tu Z, Luo P, Fang Z, Zhang L, Huang K, Wu L
Cell death & disease 2026 Jan 8;17(1):181
Cell death & disease 2026 Jan 8;17(1):181
HSP90AA1 restrains clear cell renal cell carcinoma progression by promoting CADM1 expression and suppressing the PI3K-AKT pathway through interaction with FBXO7.
Yang W, Li Y, Li Z, Jiang C, Deng X, Peng D
Cell death discovery 2026 Jan 8;12(1):6
Cell death discovery 2026 Jan 8;12(1):6
GLCCI1 alleviates airway remodeling in asthmatic mice by inhibiting ZEB1-mediated epithelial-mesenchymal transition.
Yang Q, Wang W, Zhu G, Xun H, Xun Q
Respiratory research 2026 Jan 7;27(1):43
Respiratory research 2026 Jan 7;27(1):43
EIF4A3/circPTGR1/miR-4725-5p positive- feedback loop promotes colorectal cancer progression via FAK/AKT signaling pathway.
Dong Y, Ding YH, Yang X, Song XH, Lei XT, Tang YN, Zhang XE, Huang WC, Zhang K, Chen JS
Molecular cancer 2026 Jan 5;25(1):28
Molecular cancer 2026 Jan 5;25(1):28
PPIA regulates fatty acid and glutamine metabolism in lung adenocarcinoma based on multiomics prognostic model and experiment validation.
Gan Y, Wei W, Jiang B, Zhang X, Jiang L, Teng L, Xie X, Liu Y, Xie Q, Jiang L
Scientific reports 2026 Jan 5;16(1):4154
Scientific reports 2026 Jan 5;16(1):4154
Artemisinin-hydroxychloroquine combination from traditional antimalarial medicine attenuates pulmonary fibrosis via PI3K/AKT/GSK3β-mediated inhibition of epithelial-mesenchymal transition.
Zhang L, Yu L, Deng D, Liang Q, Du H, Mei M, Deng C, Song J, Guo W
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120717
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120717
Isobavachalcone ameliorates TNBS-induced Crohn's disease-like colitis via GPR84-PI3K-AKT axis.
Sun Y, Xu F, Wang J, Liu Y, Hou T, Zhou H, Yuan W, Tang H, Fu D, Liang X
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120575
Journal of ethnopharmacology 2026 Jan 30;355(Pt A):120575
SCHEMBL4796824: a multifaceted antitumor agent targeting microtubule dynamics, DNA damage, and Wnt/β-catenin signaling in ovarian cancer cells.
Ma C, Ding X, Wang B, Zhu X, Zhang Y, Ding M, Ding X, Zhou J, Zuo D, Huang Y, Ma Y, Chen G
Journal of ovarian research 2026 Jan 3;19(1):42
Journal of ovarian research 2026 Jan 3;19(1):42
SULT1E1 exerts a protective role in COPD by inhibiting the AKT pathway: an in vivo and in vitro study.
Song W, Zhang W, Wang F, Pang S, Zhou J, Li X
Scientific reports 2026 Jan 26;16(1):6238
Scientific reports 2026 Jan 26;16(1):6238
Mechanistic Language Modeling and Oxygenated 3D Screening Reveal Berberine and Enzalutamide Synergy in Resistant Prostate Cancer.
Lo CH, Shi K, Kafadarian L, Bermudez A, Diaz J, Edwards L, Hong Y, Chen Z, Hwang H, Yan W, Levinson A, Damoiseaux R, Hsieh CJ, Stoyanova T, Goldstein AS, Lin NYC
bioRxiv : the preprint server for biology 2026 Jan 26;
bioRxiv : the preprint server for biology 2026 Jan 26;
Inhibition of the RORC/GPX4 mediated ferroptosis regulatory axis suppresses tumor growth and alleviates enzalutamide resistance in prostate cancer.
Li Y, Zhang B, Zhang Z, Yan W, Wang H, Xu X, Lv A, Liao Z, Guo L
Cellular & molecular biology letters 2026 Jan 24;31(1):11
Cellular & molecular biology letters 2026 Jan 24;31(1):11
Antitumor Effects of Broadleaf Vetch Against Esophageal Squamous Cell Carcinoma Through Dual Mechanisms: Suppressing EMT and Inducing Ferroptosis with Predicted Hepatorenal Toxicity-An Integrative Network Pharmacology and Toxicology Study.
Xing Y, Chen S, Hu K, Cui Z, Shao Y, Zhu J, Chen Z, Chen J, Deng W, Ding C, Zhao J
Cancers 2026 Jan 24;18(3)
Cancers 2026 Jan 24;18(3)
Hypoxic glycolysis-driven histone lactylation activates NHE7 to promote endometrial cancer progression via COX6C-mediated endoplasmic reticulum stress.
Yang S, Wu T, Cao Z, Chen Z, Ma Y, Wang T, Qian L, Huang X
Apoptosis : an international journal on programmed cell death 2026 Jan 23;31(2):55
Apoptosis : an international journal on programmed cell death 2026 Jan 23;31(2):55
SPIB suppresses protective autophagy via the IFIT2/PINK1/Parkin axis to promote anoikis in colorectal cancer.
Deng Q, Chen Y, Chen Z, Fu Z
Cancer cell international 2026 Jan 22;26(1)
Cancer cell international 2026 Jan 22;26(1)
Establishing a Non-Surgical Mouse Model of Laryngopharyngeal Reflux Disease: Acid-Induced Epithelial Disruption and Protective Role of N-Acetylcysteine.
Chung YY, Kim B, Lee J, Kwak S, Jung M, Kim YS, Baek SK
Cells 2026 Jan 22;15(2)
Cells 2026 Jan 22;15(2)
Clinical significance of CXCL17 in cervical cancer.
Zhai J, Pang T, An Y, Wang J, Zhang X, Zhang L, Zhang L, Dong L
Medicine 2026 Jan 2;105(1):e46178
Medicine 2026 Jan 2;105(1):e46178
HOXB4 Promotes Bladder Cancer Progression in Part Through Transcriptional Activation of Smoothened.
Jin Z, Yang W, Peng Y, Ma L, Li Z, Dong J, Ji Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Jan 15;40(1):e71388
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Jan 15;40(1):e71388
BCAR3 Hypomethylation as a Potential Diagnostic Marker for Thyroid Cancer and Its Mechanism via Promoting EMT and AKT/mTOR Pathway.
Yu W, Mao Y, Yin Y, Yang J, Zhang Y, Huang X, Zhang Y, Jiang C, Yang R
Cancers 2026 Jan 15;18(2)
Cancers 2026 Jan 15;18(2)
Methylation-induced silencing of AZGP1 enhances prostate cancer metastasis by stimulating tumoral glycolysis.
Li L, Luo J, Zhao L, Tian L, Wang J, Cheng Y, Li X
Cellular & molecular biology letters 2026 Jan 14;31(1):5
Cellular & molecular biology letters 2026 Jan 14;31(1):5
Cuproptosis of bronchial epithelial cells triggers airway remodeling in chronic asthma.
Wang M, Liu C, Li Z, Wang Y, Li Y, Pei F
Scientific reports 2026 Jan 13;16(1):4621
Scientific reports 2026 Jan 13;16(1):4621
HPGDS promotes tubular injury and interstitial inflammation in diabetic nephropathy by activating canonical pyroptosis pathway.
Huang Y, Li S, Li W, Zhang T, Lu Z, Li C, Zhu X, Yang T, Lu Q, Dong B, Wang J, Zhou W, Yan M
International immunopharmacology 2026 Jan 1;168(Pt 2):115911
International immunopharmacology 2026 Jan 1;168(Pt 2):115911
Linarin Suppresses the Progression of Colorectal Cancer by Inhibiting the HIF-1α/PD-L1 Axis.
Wang H, Jiang R, Luan P
Molecular carcinogenesis 2026 Feb;65(2):232-245
Molecular carcinogenesis 2026 Feb;65(2):232-245
Shionone ameliorates pulmonary fibrosis by activating mitophagy via PINK1-Parkin pathway.
Su Y, Fu Q, Wu X, Che X, Jiang Z, Li X
Toxicology and applied pharmacology 2026 Feb;507:117693
Toxicology and applied pharmacology 2026 Feb;507:117693
Dynamin-Related Protein 1-Dependent Disruption of Mitochondrial Homeostasis Drives Blue Light-Induced Epithelial-Mesenchymal Transition in Retinal Aging.
Li ZY, Yang D, Huang Y, Li Y, Zhao T, Xu Y
Aging cell 2026 Feb;25(2):e70416
Aging cell 2026 Feb;25(2):e70416
3-Deoxy-3β-syringoylamino-betulinic acid Reduces Breast Tumor Growth and Lung Colonization, With Associated Downregulation of the RAS/RAF/MEK/ERK Pathway.
Liu H, Su PW, Song H, Wang C, Shan P, Zhang H
Chemistry & biodiversity 2026 Feb;23(2):e02436
Chemistry & biodiversity 2026 Feb;23(2):e02436
HIF-2α / HILPDA promotes ferroptosis sensitivity in placenta trophoblast cells of early-onset preeclampsia.
Wang Q, Yang N, Chen H, Ding B, Dou C, Wang X, Pan X, Wang X, Li X
Placenta 2026 Feb;174:126-137
Placenta 2026 Feb;174:126-137
Differentiating Damp-Heat and Cold-Damp Diarrhea in Rat Models via Gut Microbiota Dysbiosis and Short-Chain Fatty Acid Profiling.
Zhang H, Song X, Mi W, Ji P, Wei Y, Hua Y
MicrobiologyOpen 2026 Feb;15(1):e70164
MicrobiologyOpen 2026 Feb;15(1):e70164
COL1A1 promotes clear cell renal cell carcinoma progression through the Wnt/β-catenin signaling pathway.
Ji X, Yun Y, Zhu Z, Wu T, Ruan M, Fan Y, Zhang Q
Cellular signalling 2026 Feb;138:112259
Cellular signalling 2026 Feb;138:112259
Acute sleep deprivation reduces thermotolerance and exacerbates heat stroke via disruption of intestinal barrier integrity in rats.
Li L, Xie Y, Gong Y, Chen J, Wang Y, Pei Y, Zhou J, You J, Cao Y, Song M, Sun H, Ma W, Wang M, Ma J, Chen J, Chang W, Song Q, Wang Y, Wang Q, Xu S
Sleep medicine 2026 Feb;138:108699
Sleep medicine 2026 Feb;138:108699
Polystyrene Microplastics Exposure Aggravates Clear Cell Renal Cell Carcinoma Progression via the NF-κB and TGF-β Signaling Pathways.
Ye S, Xiang J, Zhou S, Ge Q, Anwaier A, Chang K, Wei G, Lu J, Tian X, Zhu S, Jiang Y, Zhang W, Cai T, Xu M, Ye D, Xu D, Wang T, Zhang H, Xu W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(8):e18500
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Feb;13(8):e18500
Lipid Nanoparticles Enable Efficient EGF mRNA Delivery for Wound Healing.
Zhou Q, Liu W, Ge J, Liu X, Wang H, Fu W, Deng D
Pharmaceutics 2026 Feb 9;18(2)
Pharmaceutics 2026 Feb 9;18(2)
Discovery of novel small molecule inhibitor targeting the tumor promoting effect of transcription factor PLAGL2.
Ding Y, Wang Z, Xia X, Wang J, Li Z, Gu C, Hao C, Xu K, Gao M, Yin H, Chen S, Gong X, Zhou W, Zhang M, Yang Y, Zhang D, Dai B, Zhang M
European journal of medicinal chemistry 2026 Feb 5;303:118471
European journal of medicinal chemistry 2026 Feb 5;303:118471
Interleukin-7 induces EMT to promote tumor growth and metastasis in NSCLC via Notch1/TGF-β pathway.
Shao Y, Cheng H, Ni W, Zhang A, Li C, Li X, Fu Y, Ming J
Scientific reports 2026 Feb 5;16(1)
Scientific reports 2026 Feb 5;16(1)
Engineered CCR2 Cell Membrane-Wrapped Cepharanthine Liposomes for Potential Targeted Attenuation of Acute Lung Injury.
Qing Y, Zhao W, Xue L, Luo Y, Gao Y, Sun X, Li F, Dai L, Mo J, Xu G, Bi Z, Yang S, Hee WT, Li J, Leng L
Cells 2026 Feb 4;15(3)
Cells 2026 Feb 4;15(3)
Exosomal microRNAs of tuberculous pleural effusion orchestrating TGF-β signaling mediate pleural fibrosis.
Jiang LJ, Zheng YY, Liang LM, Jia ZH, Du RH, Huang H, Dai X, Cheng PP, Zhao LQ, Li Q, Jiang YH, Cui XL, Ye SY, Hu SH, Zhang HD, Lian CY, Feng X, Song LJ, Yu F, He XL, Xiong L, Xiang F, Wang X, Liu AD, Wang M, Ye H, Ma WL
Respiratory research 2026 Feb 3;27(1)
Respiratory research 2026 Feb 3;27(1)
VAMP7 governs ferroptosis suppression and cisplatin resistance in esophageal cancer: a dual-targeting therapeutic paradigm.
Zhu J, Xie M, Dai L, Yang Z, Xue W, Jiang Z, Zhou J
Cancer cell international 2026 Feb 3;26(1)
Cancer cell international 2026 Feb 3;26(1)
DMBX1 expression in colon cancer and its impact on prognosis and the tumor microenvironment.
Zhang K, Hu X, Chen J, Zhao Z, Yin X, Zhou L, Wang B
BMC medical genomics 2026 Feb 3;19(1)
BMC medical genomics 2026 Feb 3;19(1)
Fibroblast Growth Factor 11 Improves Fertility by Alleviating Intrauterine Adhesionss in Rats Through Inhibition of the Transforming Growth Factor-β1/Smad Pathway.
Yin F, Fang Q, Liu X, Yu X, Rong Y, Shi D, Xu Z, Gong F, Chen M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Feb 28;40(4):e71602
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Feb 28;40(4):e71602
Fecal microbiota transplantation reduces susceptibility to post-antibiotic CLP-induced sepsis by modulating the gut microbiota and its metabolites.
Mo C, Shao R, Shi Z, Lou X, Xue J, Ning D, Liu Y, Jiang W, Wei X, Xiao J, Wang F, Chen G
BMC microbiology 2026 Feb 28;26(1)
BMC microbiology 2026 Feb 28;26(1)
TMT proteomics reveals that miR-425-5p promotes proliferation and metastasis of malignant melanoma by inhibiting SCARA5.
Ni Q, Ying D, Chang J, Yu H, Li X
Cancer cell international 2026 Feb 24;26(1)
Cancer cell international 2026 Feb 24;26(1)
ACTG1 facilitates proliferation and epithelial-mesenchymal transition-mediated metastasis via COL21A1 in gastric cancer.
Li S, Lan B, Pan L, Sun M, Cui M, Huang Y, Wei S, Huang H
iScience 2026 Feb 20;29(2):114666
iScience 2026 Feb 20;29(2):114666
Functional effects of EpCAM N-glycosylation in MDA-MB-468 breast cancer cells.
Jenkinson NM, Oza H, Yarema KJ, Glunde K
Scientific reports 2026 Feb 20;16(1)
Scientific reports 2026 Feb 20;16(1)
AMPK Deficiency Induces Corneal Epithelial Barrier Dysfunction by Modulating Energy Homeostasis.
Yang Y, Yan K, Tang Y, Liu Z, Zhu L, Wei M, Huang C, Liu Z, Zhao D, Ren S
Investigative ophthalmology & visual science 2026 Feb 2;67(2):47
Investigative ophthalmology & visual science 2026 Feb 2;67(2):47
PARP-1 couples β-catenin/TCF4 signaling to epithelial-mesenchymal transition in endometriosis.
Zhang L, Li X, Kong L, Hou X, Li B, Zhang Y, Wang J
Scientific reports 2026 Feb 2;16(1):6940
Scientific reports 2026 Feb 2;16(1):6940
CD177(+) neutrophils alleviate acute pancreatitis-associated lung injury by protecting colonic barrier and restoring gut microbiota.
Ji L, Chen Y, Gong L, Li J, Xiong Y, Zhao Y, Li Y, Han Z, Yang Z, Jiang Q, Wu D
Cellular and molecular life sciences : CMLS 2026 Feb 18;83(1)
Cellular and molecular life sciences : CMLS 2026 Feb 18;83(1)
SREBP1 knockdown triggers ferroptosis by suppressing the Nrf2-XCT/GPX4 axis in ovarian cancer.
Nie R, Zhou H, Chen L, Quan H, Zhang Y, Lin Z
Cell death discovery 2026 Feb 18;12(1)
Cell death discovery 2026 Feb 18;12(1)
Growth differentiation factor 15 promotes the malignant progression of multiple myeloma via activation of PI3K/Akt/NF-κB signaling pathway.
Fan H, Wu Y, Peng Y, Wang L, Tu S, Peng H, Yang J, Li X, Shi Z, Li M, Song K
Journal of translational medicine 2026 Feb 17;24(1)
Journal of translational medicine 2026 Feb 17;24(1)
Mitochondrial uncoupling sensitizes gastric cancer cells to elesclomol-induced cuproptosis via FDX1/DLAT upregulation.
Lu Y, Li Y, Sun X, Li X, Zhao S, Fang Y, Qiu W, Luo C, Qi W
Free radical biology & medicine 2026 Feb 16;244:284-295
Free radical biology & medicine 2026 Feb 16;244:284-295
Cadmium exposure induces renal fibrosis by inhibiting hsa_circ_0075684/miR-363-3p/KLF4 signaling pathway.
Zhou J, Huang Y, Li G, Zhao Z, Deng Y, Xian S, Hu Y, Yi M, Liu L
Scientific reports 2026 Feb 13;16(1)
Scientific reports 2026 Feb 13;16(1)
Development and characterization of immortalized mouse intestinal epithelial cell lines.
Zhou JY, Espenschied ST, Lu Q, Karell PE, Lewis KJ, Newhall KP, Han Y, Bambroo M, Job A, Stappenbeck TS
Scientific reports 2026 Feb 11;16(1)
Scientific reports 2026 Feb 11;16(1)
Gingerenone A ameliorates airway inflammation and remodeling in asthma by modulating the TLR4/MyD88/NF-κB pathway.
Zhu Y, Chen L, Lin J, Chen M, Wu W, Chen Y, Xuan L
Journal of ethnopharmacology 2026 Feb 10;356:120656
Journal of ethnopharmacology 2026 Feb 10;356:120656
The circadian clock component PER2 deficiency aggravates airway epithelial remodeling through Wnt/β-catenin signaling pathway.
Zhang S, Lin J
Respiratory research 2026 Feb 10;27(1)
Respiratory research 2026 Feb 10;27(1)
Identification and biological evaluation of benzimidazole-based compounds as novel TGFβR1 inhibitors.
Tseng HJ, Wu YW, Chen YL, Lin TE, Fang-Chin YT, Wu YL, Sung TY, Yen SC, Hsieh JH, Hsu KC, Pan SL
Journal of enzyme inhibition and medicinal chemistry 2026 Dec;41(1):2600746
Journal of enzyme inhibition and medicinal chemistry 2026 Dec;41(1):2600746
Identification of mitochondrial permeability transition-related gene signatures to predict lung adenocarcinoma survival and drug response.
Liu L, Gao M, He W, Wang M, Zhou S, Wang X, Shu Y
Cell cycle (Georgetown, Tex.) 2026 Dec;25(1):1-35
Cell cycle (Georgetown, Tex.) 2026 Dec;25(1):1-35
The P7 peptide antagonizes bFGF-induced malignant behaviors of ovarian cancer by inhibiting MEK/ERK signaling pathway.
Yang Z, Wei W, Nie D, Zhang M, Chen Q
Future science OA 2026 Dec;12(1):2615619
Future science OA 2026 Dec;12(1):2615619
CircSMAD4 shapes matrix-remodeling TAMs in lung adenocarcinoma.
Yu Z, Wang X, Zheng Y, He Y, Lin J, Xiao Y, Mo B, Xie H, Hang S, Gao X, Xu P, Liu Y, Xiao H
Non-coding RNA research 2026 Aug;19:40-57
Non-coding RNA research 2026 Aug;19:40-57
Mitochondrial IRF3 drives pulmonary fibrosis by impairing mitophagy and triggering ferroptosis.
Jiashu Z, Jingbao L, Hua F, Meiqi S, Jing L, Mengyao W, Wei Z
Cellular signalling 2026 Aug;144:112517
Cellular signalling 2026 Aug;144:112517
INHBB promotes liver metastasis of colorectal cancer via regulation of TGF-β/Smad signaling, EMT and anoikis resistance.
Yang N, Dai D, Zhao J, Zhao H, Jiang H, Liu J, Liu F, Chen X
Tissue & cell 2026 Apr;99:103258
Tissue & cell 2026 Apr;99:103258
GSDME Deficiency Suppresses ER Stress-Induced Autophagic Cell Death via mTOR/S6K1 Activation in Hepatobiliary Carcinomas.
Sun L, Tang G, Zhang M, Zhou H, Liu Y, Cao X, Zhang J
Biochemical genetics 2026 Apr;64(2):2339-2352
Biochemical genetics 2026 Apr;64(2):2339-2352
PSMA-Targeting Macrophage Membrane-Coated Nanoparticles for Precision Diagnosis and Combination Therapy of Prostate Cancer.
Zhang K, Gao B, Wang J, Li Y, Xu C, Yang F, Liu S, Li H, Zhang C, Meng X, Shi Z, Zhang R, Zhang R, Wang Z, Wen W, Zhang Q, Zou Y, Han D, Bian H, Qin W
Exploration (Beijing, China) 2026 Apr;6(2):20240393
Exploration (Beijing, China) 2026 Apr;6(2):20240393
Photobiomodulation therapy inhibits ISO-induced myocardial remodeling in mice through modulating TGF-β/Smad7 and PI3K/AKT pathways.
Jiang Y, Xu Z, Sun X, Sun S, Ding K, Li J, Chu W, Chang J, Sun W, Shi L
Photodiagnosis and photodynamic therapy 2026 Apr;58:105389
Photodiagnosis and photodynamic therapy 2026 Apr;58:105389
Angiotensin II type 1 receptor signaling promotes bladder cancer progression and its inhibition by Losartan.
Yamanaka R, Miura K, Yamasaki N, Ogata S, Nakamura M, Inaba T, Bold-Erdene A, Enkhbaatar U, Mirkatouli FB, Miura S, Hosomi N, Kobatake K, Takemoto K, Kohada Y, Tasaka R, Hatayama T, Yukihiro K, Shikuma H, Iwane K, Hinata N, Kaminuma O
Hypertension research : official journal of the Japanese Society of Hypertension 2026 Apr;49(4):1480-1494
Hypertension research : official journal of the Japanese Society of Hypertension 2026 Apr;49(4):1480-1494
Core fucosylation of NCEH1 by FUT8 promotes progression of high-grade serous ovarian cancer by driving tumor-associated macrophage M2 polarization.
Pei X, Wang F, Liu X, Lei Y, Chen Y, Liu B, Sun R, Li P, Bi J, Liu S
Oncogene 2026 Apr;45(12):1128-1144
Oncogene 2026 Apr;45(12):1128-1144
Loss of TRAIP Could Attenuate the Breast Cancer Cells Development by Regulating PLSCR4 Stabilization.
Dong Z, Chen Q, Li F, Xie W, Ma X, Ge S, Sun M, Zhao X, Zhang Z, Zhang W, Wei D, Huang S
Journal of biochemical and molecular toxicology 2026 Apr;40(4):e70825
Journal of biochemical and molecular toxicology 2026 Apr;40(4):e70825
CircRNA SLAIN1 is associated with reduced malignancy progression of glioblastoma and the M2-like polarization of tumor-associated macrophages via miR-1225-3p/NLRX1 axis.
Ai M, Li F, Huang Z, Liu C, Liao H, Huang X, Li Z, Wang B, Zhang C, Xu A, Lin J, Xu R, Yuan Y, Tian Y
International journal of biological macromolecules 2026 Apr;357:151212
International journal of biological macromolecules 2026 Apr;357:151212
Pentraxin-related protein PTX3 alleviates blast-induced acute lung injury by promoting efferocytosis to eliminate ferroptotic alveolar epithelial cells in vitro.
Weng CM, Kang JY, Duan ZX, Zhu YG, Cheng XY, Zhang DD, Guo L, Yang GM, Wang JM
The FEBS journal 2026 Apr;293(7):1970-1993
The FEBS journal 2026 Apr;293(7):1970-1993
Mechanism of Gzma-mediated GEF-H1 activation in intestinal epithelial cells leading to intestinal barrier dysfunction in sepsis.
Lin Z, Jiang H, Ni C, Deng L, Yang H, Wang R, Liu P, Li X, Yu Y, Li W, Liao B, Liu J, Li W, Yang J, Chao Y, Liu H, Wu X, Ren J, Zhao Y
Clinical and translational medicine 2026 Apr;16(4):e70651
Clinical and translational medicine 2026 Apr;16(4):e70651
eIF3i facilitates NELFCD translation to promote metastasis via regulating EMT and invadopodia.
Huang Q, Zhao J, Zhang Y, Zhou Y, Yang X, Chen X, Wei M, Han J, Zhang Y
British journal of cancer 2026 Apr;134(7):996-1005
British journal of cancer 2026 Apr;134(7):996-1005
Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression.
Guo S, Chen X, Wang H, Zhou J, Lu P, Liu J, Chai K, Zhang J, Yang S, Lu S, Gao Y, Jin Z, Tao X, Hu Z, Li Q, Wu J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(23):e07008
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(23):e07008
SLC2A3-Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion.
Ding Y, Tian Y, Ren W, Hu X, Li M, Liu B, Chen C, Lu Y, Li L, Yan W, Li K
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(22):e16622
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(22):e16622
Tumor-Associated Macrophage-Derived CXCL1 Promotes Endometrial Cancer Progression Through the CXCR2/NF-κB Pathway.
Xia R, Qi D, Ji B, Dai Y, Kong X
Cancer science 2026 Apr;117(4):1026-1042
Cancer science 2026 Apr;117(4):1026-1042
Three-dimensional patient-derived endometriosis model for drug evaluation.
Li Y, Shao W, Gao X, Wang Y, Li J, Zhang L, Xing Y, Su W, Cheng Y, Wang L, Liu S
Acta obstetricia et gynecologica Scandinavica 2026 Apr;105(4):629-646
Acta obstetricia et gynecologica Scandinavica 2026 Apr;105(4):629-646
Novel transcription factor zinc finger 514 suppresses lung adenocarcinoma progression and enhances cisplatin sensitivity via transcriptional repression of COL1A1.
Sun S, Ma G, Cheng L, Zhang H, Fan G, Wu L, Zhang X, Xue F, Fu T, Ji X, Wan Q, Liu Y
British journal of cancer 2026 Apr 9;
British journal of cancer 2026 Apr 9;
Advanced glycation end products promote Porphyromonas gingivalis dissemination via an ROS-dependent, inflammation-independent mechanism.
Liu Y, Zhu C, Mao C, Zhang X, Wang M, Xu X, Guo M, Zhang R, Guan C, Wang C, Ye K, Xu D
Cell reports 2026 Apr 8;45(4):117252
Cell reports 2026 Apr 8;45(4):117252
O-GlcNAc Modification Orchestrates HUWE1-Mediated Ubiquitination of TfR1 to Regulate Ferroptosis and Trophoblast Syncytialization in Preeclampsia.
Zhang H, Li M, Zhang J, Sun Q, Jin X, Liu R, Li X, Chen X, Wang A, Luo Z, Shang Y, Kong Y
Free radical biology & medicine 2026 Apr 8;
Free radical biology & medicine 2026 Apr 8;
SIRT1-regulated mitophagy mitigates lipotoxicity-induced ferroptosis in diabetic kidney disease.
Jian Y, Zeng Y, Wang Z, Zhou X, Zhang H, Liang D, Yan R
Apoptosis : an international journal on programmed cell death 2026 Apr 7;31(4)
Apoptosis : an international journal on programmed cell death 2026 Apr 7;31(4)
Prostaglandin E(2)-driven dedifferentiation of Schwann cells leads to perineural invasion in pancreatic ductal adenocarcinoma.
Wang L, Liu Q, Zhang Z, Yang S, Tang J, Pan G, Zheng Y, Zhuang Y, Wu Q, Weng S, Gao F, Dong J
Signal transduction and targeted therapy 2026 Apr 7;11(1)
Signal transduction and targeted therapy 2026 Apr 7;11(1)
UCHL3 Promotes Triple-Negative Breast Cancer Metastatic Potential Through Enhancing Cell Migration and Invasion.
Xu Q, Yang W, Li C, Yang M, Zhu X, Wang W, Lin Y, Gan Z, He T, Wu X, Li X
Applied biochemistry and biotechnology 2026 Apr 7;
Applied biochemistry and biotechnology 2026 Apr 7;
Extracellular vesicles derived from senescent hepatocytes drive pan-cancer metastasis in aging.
Li H, Zhao R, Wan L, Yuan Y, Ma E, Li Y, Chen Z, Liu B, Song Y, Cao Z, Jiao X, Wang Y, Wu P, Jin H, Li J, Yang X, Huang L, Zhang Y, Yang K, Huo J, Jin H, Zhong H, Min M, Zhang S, Cao Y, Li W, Zhang R, Wei C
Nature aging 2026 Apr 6;
Nature aging 2026 Apr 6;
Discovery of indolinone-based covalent ULK1 inhibitors that suppressed autophagy and induced apoptosis against colorectal carcinoma.
Ye J, Wang D, Pang H, Liu Q, Pan Z, Wang L, Liu B, He G
European journal of medicinal chemistry 2026 Apr 5;307:118633
European journal of medicinal chemistry 2026 Apr 5;307:118633
A conserved re-epithelialization program underlies malignancy in pancreatic ductal adenocarcinoma.
Zhuo M, Li Y, Zhang Y, Yang C, Zou D, Xu W, Han J, Wang S, Deng H, Pan X, Dun R, He R, Shi Y, Han X, Zhang T, Wang W, Dai M, Xu Q, Liu L, Wang W, Liu Y, Liu M, Deng Z, Zhao Y, Wu W, Peng J, Chen M, David CJ
Cancer cell 2026 Apr 30;
Cancer cell 2026 Apr 30;
A Biomimetic Mn-Doped Polydopamine Nanoplatform for MRI-Enabled Synergistic Therapy to Enhance Lenvatinib Efficacy in Liver Cancer.
Luo W, Ma Y, Zhu W, Nie R, Wu Y, Shan D, Xu S, Song HY, Hu H
ACS applied materials & interfaces 2026 Apr 29;18(16):22769-22783
ACS applied materials & interfaces 2026 Apr 29;18(16):22769-22783
Vitexin attenuates gastric precancerous lesions with EGFR as a potential target based on network pharmacology and molecular simulations.
Liu J, Liu N, Ye Y, Ye Z, Jiang D, Huang S
Scientific reports 2026 Apr 23;
Scientific reports 2026 Apr 23;
Ophiopogon japonicus Polysaccharides Promote Microbial Production Of Chenodeoxycholic Acid To Alleviate Ulcerative Colitis in Mice by Inhibiting the STING1-Related NF-κB Pathway.
Gao X, Zhang C, Zhao Z, Chen Y, Lei H, Cao Z, Yu W, Lin W, He Y, Li X, Xiang Q, Zhang Z, Zhang L, Chen G
Journal of agricultural and food chemistry 2026 Apr 22;74(15):12087-12101
Journal of agricultural and food chemistry 2026 Apr 22;74(15):12087-12101
Targeting keratin 6 A overcomes gemcitabine resistance by restoring equilibrative nucleoside transporter 1 and TAM-mediated metabolic compensation in pancreatic cancer.
Zhang J, Wang X, Zeng S, Tang B, Yang X, Xie S, Sun H, Wang R, Xia R, Li J, Wang H, Shi Z, Gu J, Wei D
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 Apr 17;87:101404
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2026 Apr 17;87:101404
KIAA1429 promotes clear cell renal cell carcinoma progression by regulating MYC mRNA stability.
Zhu X, Shen C, Zhang Y, Chen X, Zhang W, Zheng B, Chen Z
iScience 2026 Apr 17;29(4):115198
iScience 2026 Apr 17;29(4):115198
Atmospheric particulate matter impairs pulmonary barriers by triggering FTH1-mediated ferroptosis.
Yue H, Wang J, Li Y, Dong H, Dong Y, Liu T, Li J
iScience 2026 Apr 17;29(4):115177
iScience 2026 Apr 17;29(4):115177
Curcumin Induces Macrophages Polarization to Alleviate Ulcerative Colitis by Regulating Macrophage Nuclear Morphology via Affecting the Interaction Between Enteric Glial Cells Glial-Derived Neurotrophic Factor and Casein Kinase 2.
Zhang H, Ren M, An Q, Liu Z, Li C, Bai Y, Shi D, Wang Y, Qiu F, Lu S
Phytotherapy research : PTR 2026 Apr 16;
Phytotherapy research : PTR 2026 Apr 16;
IL-5 promotes airway remodeling in asthma by mediating epithelial-mesenchymal transition via the AKT/NLRP3 pathway.
Zhao L, Lin Y, Dou M, Su H, Han L, Wu J, Lu Y, Bao W, Zhang M
International immunopharmacology 2026 Apr 15;175:116422
International immunopharmacology 2026 Apr 15;175:116422
Ginsenoside Rg3 synergizes with near-infrared photothermal therapy to suppress prostate cancer progression by inhibiting RAS signaling and enhancing ARL11-mediated macrophage reprogramming.
Zhang H, Chang Y, Fu Q, Jin T, Zhang S, Zhang M
International immunopharmacology 2026 Apr 15;175:116417
International immunopharmacology 2026 Apr 15;175:116417
Phenethyl Isothiocyanate Suppresses Hepatocellular Carcinoma Progression and Immune Evasion via ZNF652 Regulation of PD-L1.
Ren D, Wu J, Zhu J, Xie C, Zhong C, Cao H, Han H, Zhu J
Phytotherapy research : PTR 2026 Apr 15;
Phytotherapy research : PTR 2026 Apr 15;
CRYM suppresses glioblastoma progression by inhibiting the TGFβ1/Smad-EMT signaling pathway.
Xu Y, Zhao P, Yao Z, Shen T, Ding S, Hua Y, Zhang F, Jiang X, Di G, Xia H
Journal of neuro-oncology 2026 Apr 13;177(2)
Journal of neuro-oncology 2026 Apr 13;177(2)
lncRNA DLGAP1-AS2 Modulates the TGF-β/Smad Signaling Pathway to Regulate Epithelial-Mesenchymal Transition in Renal Cell Carcinoma.
Cao H, Zhu J, Zhang L, Li L, Ma L, Xie C
Biochemical genetics 2026 Apr 11;
Biochemical genetics 2026 Apr 11;
VHL-recruiting PROTAC attenuates AKI-CKD transition via simultaneous degradation of Smad3 and stabilization of HIF-2α.
Ruan Y, Wang D, Xu Y, Yang J, Chen Y, Fan J, Tang SCW, Chen W, Wang X
Cell death & disease 2026 Apr 10;17(1)
Cell death & disease 2026 Apr 10;17(1)
TRIM29 suppresses malignant progression in lung squamous cell carcinoma by shaping an immunosuppressive tumor microenvironment.
Zhou X, Jia W, Jiang H, Zhong H, Sun J, Ma R, Wu Z, Lin Z, Lu L, Chen H
Scientific reports 2026 Apr 10;
Scientific reports 2026 Apr 10;
SEMA6A overexpression inhibited tumor growth and metastasis in colorectal cancer.
Huang C, Ma L, Zhao Q, Mi Y, Tian Y
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2025;58:e14896
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2025;58:e14896
LTF regulates glioblastoma progression and temozolomide resistance via the NF-κB signaling pathway.
Gao L, Xiao H, Lu H, Ma J, Zhu H
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2025;58:e13821
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2025;58:e13821
ZMIZ2/MCM3 Axis Participates in Triple-Negative Breast Cancer Progression.
Zou X, Sun M, Jiang X, Yu J, Li X, Nie B
Oncology research 2025;34(1):15
Oncology research 2025;34(1):15
CEP55 Promotes Acral Melanoma Progression via MAPK Pathway and Predicts Survival Following Immunotherapy.
Cao M, Zhang R, Hong A, Ye S, Qiu Z, Li D, Lin T, Wang Y
Oncology research 2025;33(9):2507-2527
Oncology research 2025;33(9):2507-2527
CYMP-AS1 Promotes Ovarian Cancer Progression by Enhancing the Intracellular Translocation of hnRNPM and Reducing the Stability of AXIN2 mRNA.
Wang Y, Meng Y, Xia W, Liang Y, Wang Y, Li P, Fang L
Oncology research 2025;33(8):2141-2159
Oncology research 2025;33(8):2141-2159
ETV1 transcriptional manipulation of KIFC1 regulates the progression of pancreatic cancer.
Hu F, Bai Z, Wang Y, Tang H, Zhou J
Oncology research 2025;33(7):1723-1737
Oncology research 2025;33(7):1723-1737
Terpinen-4-ol suppresses proliferation and motility of cutaneous squamous cell carcinoma cells by enhancing calpain-2 expression.
Rong D, Su Y, Zeng Z, Yang Y, Lu H, Cao YU
Oncology research 2025;33(3):605-616
Oncology research 2025;33(3):605-616
ARPC1B Promotes Clear Cell Renal Cell Carcinoma Progression via the Wnt/β-Catenin Signaling Pathway.
Peng J, Xue Y, Cai Z, Li Z, Han K, Lin X, Li Y, Zhuo Y
Oncology research 2025;33(10):3127-3154
Oncology research 2025;33(10):3127-3154
Smad7 ameliorate small airway remodeling in COPD by modulating epithelial-mesenchymal transition.
Liu X, Sun S, He S, Xie L
Tobacco induced diseases 2025;23
Tobacco induced diseases 2025;23
Platelet-rich fibrin promotes mesothelial cell proliferation and peritoneal repair by up-regulating calretinin to prevent postoperative intestinal adhesion.
Li X, Guo Y, Wang Z, Guo X, Wang J, Zhang J, Zhang T, Wang J, Li T, Zhou J, Zhang N, Amin B, Zhu B
International journal of medical sciences 2025;22(6):1254-1268
International journal of medical sciences 2025;22(6):1254-1268
Cancer-associated Fibroblast-like Cells Promote Osteosarcoma Metastasis by Upregulation of Phosphoserine Aminotransferase 1 and Activation of the mTOR/S6K Pathway.
Feng L, Xiao G, Chen Y, Ye T, Fan L, Xie Y, Mei T, Wang L, Ge J, Ye C, Chen J
International journal of biological sciences 2025;21(9):4153-4171
International journal of biological sciences 2025;21(9):4153-4171
Identification of MAPK12 as a Prognostic Biomarker for Esophageal Carcinoma Using Bioinformatics and Machine Learning.
Gu S, Yan X, Chen S, Dong Z, Li X, Ye C, Zhao C, Yuan H, Sun X, Zhao W, Zhang P
BioMed research international 2025;2025:2605071
BioMed research international 2025;2025:2605071
Targeting interferon-stimulated gene of 20 kDa protein (Isg20) inhibits ribosome biogenesis to ameliorate the progression of renal fibrosis.
Liu X, Wang H, Wang K, Liu Y
PloS one 2025;20(7):e0322639
PloS one 2025;20(7):e0322639
Exploring the level of metabolic reprogramming and the role of prognostic factor SF3A3 in hepatocellular carcinoma through integrated single-cell landscape analysis.
Wei W, Gan Y, Zhang X, Chen Y, Huang Z, Wang S, Xie X, Li Y, Qin P, Jiang L
PloS one 2025;20(5):e0323559
PloS one 2025;20(5):e0323559
Inhibition of HPSE/SDC-2 axis-induced epithelial-mesenchymal transition for treating IC/BPS.
Chen Z, He Y, Zhang J, Ge Q, Du T, Fan Z, Zhou J, Yang X, Shen B, Wei Z
PloS one 2025;20(5):e0321730
PloS one 2025;20(5):e0321730
IGF2BP2 contributes to thyroid cancer progression by enhancing the stability of m6A-modified CTSH mRNA.
Dong L, Chen L, Qi X, Lu Q, Li Y, Hou M
PloS one 2025;20(10):e0332061
PloS one 2025;20(10):e0332061
AKAP12, mediated by transcription factor 21, inhibits cell proliferation, metastasis, and glycolysis in lung squamous cell carcinoma.
Chen J, Liao H, Wang K, Yan T, Ma S, Bai G
Open life sciences 2025;20(1):20220912
Open life sciences 2025;20(1):20220912
Exosome-Delivered circFOXP1 Upregulates Autophagy and Promotes Hepatocellular Carcinoma Progression Through Its Encoded p196 Protein Targeting the KHDRBS3/ULK1 Axis.
Zhao P, Yin C, Liu R, Shao S, Ke W, Song Z
International journal of nanomedicine 2025;20:5247-5265
International journal of nanomedicine 2025;20:5247-5265
Mechanistic Exploration of Shugan Jianpi Formula for Treating Triple-Negative Breast Cancer Under Chronic Stress: A Network Pharmacology-Guided Experimental Study.
Liu F, Li L, Zhang Y, Zhang J, Tian X, Zhang D, Zhang N, Yan T, Shi S, Wu J, Jiang S
Drug design, development and therapy 2025;19:4585-4603
Drug design, development and therapy 2025;19:4585-4603
PTPRN promotes glioma cell proliferation, migration, and invasion by regulating the EMT pathway.
Wang S, Zhao X, Li M, Zhang Y, Liu B
International journal of clinical and experimental pathology 2025;18(10):509-523
International journal of clinical and experimental pathology 2025;18(10):509-523
Promotion of human choroidal melanoma cell metastases by FOXP3 via Wnt5a/CaMKII signaling pathway.
Yuan YY, Liu YC, Zhang Q, Gao XD, Zhu YZ, Cheng K, Zhao H, Fu WW, Lei K, Sui AH, Luo WJ
International journal of ophthalmology 2025;18(10):1834-1845
International journal of ophthalmology 2025;18(10):1834-1845
Finerenone Ameliorates High Glucose-Induced Podocytes Epithelial-Mesenchymal Transition Through the Regulation of Krüppel-Like Factor 5 in Diabetic Nephropathy.
Shu J, Chen D, Chen W, Zhang X, Wang S, Chong N, Sun Z, Wang Q, Sun J, Xu Y
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:637-651
Diabetes, metabolic syndrome and obesity : targets and therapy 2025;18:637-651
Ginsenoside Rg3 exerts anticancer effects in lung cancer through metabolite Histon H3.
Xiao H, Zhang Y, Zhang B, Wu J, Li X
American journal of translational research 2025;17(5):3994-4007
American journal of translational research 2025;17(5):3994-4007
MiR-124-3p inhibits proliferation, migration, and epithelial-mesenchymal transformation in gastric cancer by targeting ITGB1.
Li Q, Zhou L, Liang Q, Qin H, Chen Y, Wang T, Wei Q, Luo Y, Li G, Huang H
American journal of translational research 2025;17(4):2500-2512
American journal of translational research 2025;17(4):2500-2512
PLXND1 from the Plexins family is a prognostic factor promoting colon cancer invasion and metastasis.
Chen W, Guo L, Wang Z, Wang Z, Dai X
American journal of translational research 2025;17(10):8243-8264
American journal of translational research 2025;17(10):8243-8264
As a New Tumor Suppressor Gene, PID1 Activates the AMPK-mTOR Signal to Inhibit the Progression of Bladder Cancer.
Sun L, Liu C, Cao Y, Li J, Yuan L
Research and reports in urology 2025;17:235-248
Research and reports in urology 2025;17:235-248
Aldose Reductase Mediated Mitophagy Promotes Epithelial-Mesenchymal Transition of Hepatocytes.
Yan J, Zhao W, Wang H, Zhou L, Li X, Wang G
Hepatic medicine : evidence and research 2025;17:141-159
Hepatic medicine : evidence and research 2025;17:141-159
Multi-Omics Analysis Reveals the transforming growth factor-β Signaling-Driven Multicellular Interactions with Prognostic Relevance in Cervical Cancer Progression.
Wang Y, Cao G, Zeng H, Zhi Y, Xu M, Wang Y, Liu M, Ruan Y, Tse KY, Zhang Q, Gao J, Han Z, Li F
Journal of Cancer 2025;16(9):2857-2876
Journal of Cancer 2025;16(9):2857-2876
A novel EMT-related risk score model for Uveal melanoma based on ZNF667-AS1 and AP005121.1.
Yang F, Ren Y, Qi D, Liu X, Xie J
Journal of Cancer 2025;16(2):460-469
Journal of Cancer 2025;16(2):460-469
COL6A2 drives clear cell renal cell carcinoma progression via integrin-dependent modulation of Wnt/β-catenin signaling.
Ji X, Yun Y, Zhu Z, Wu T, Ruan M, Fan Y, Zhang Q
Journal of Cancer 2025;16(15):4426-4439
Journal of Cancer 2025;16(15):4426-4439
Comprehensive Bioinformatics Analysis and Validation of the Mechanism of Glutamic-pyruvic Transaminase 2 in Bladder Cancer.
Dong H, Li H, Chen S, Wang Q, Zhang Y, Shi H, Zuo J, Chen J, Wang J, Wang H
Journal of Cancer 2025;16(15):4357-4370
Journal of Cancer 2025;16(15):4357-4370
Vericiguat attenuates cyclosporine A-induced nephropathy by targeting the NF-κB/TGF-β1 axis: an integrated network pharmacology, Mendelian randomization, and experimental study.
Liu X, Tang M, Lu J, Kong Y, Shen W, Zhang C, Yang X
Frontiers in immunology 2025;16:1756582
Frontiers in immunology 2025;16:1756582
Cardamonin induces apoptosis of colorectal cancer cells via targeted inhibition of the JAK/STAT3/epithelial-mesenchymal transition (EMT) signaling axis.
Wu M, Chen C, Ren D, Du Z, Liu Z, Liu W
Frontiers in pharmacology 2025;16:1739201
Frontiers in pharmacology 2025;16:1739201
Camel milk and fermented camel milk prevent dextran sulfate sodium-induced ulcerative colitis via the intestinal flora-short-chain fatty acids-mucosal barrier axis in mice.
Xu W, Dong Q, Guo Q, Li R, Abbas M, Li L, Zhang C, Zhao G
Frontiers in microbiology 2025;16:1723833
Frontiers in microbiology 2025;16:1723833
R3HDM4 influences kidney renal clear cell carcinoma progression, immune modulation, and potential links to the IGSF8 immune checkpoint.
Sun K, Li R, Xu T, Wen S, Xu DC, Wang KR
Frontiers in immunology 2025;16:1722358
Frontiers in immunology 2025;16:1722358
CHMP4A in hepatocellular carcinoma: exploring its role in tumor progression, immune modulation, and potential link to TIM3 checkpoint.
Sun K, Wen S, Guo SJ, Pan QH, Wang KR
Frontiers in immunology 2025;16:1682724
Frontiers in immunology 2025;16:1682724
MFSD12 promotes proliferation, metastasis and invasion of hepatocellular carcinoma cells and its potential correlation with HAVCR2/LGALS9 immune checkpoint axis.
Sun K, Wen S, Guo SJ, Pan QH, Wang KR
Frontiers in immunology 2025;16:1681887
Frontiers in immunology 2025;16:1681887
Prognostic modeling of glioma using epilepsy-related genes highlights PAX3 as a regulator of migration and vorinostat sensitivity.
Lin W, Lin H, Zheng Y, Wang J, Li J, Yang R, Zhang Z, Liu X, Xu X
Frontiers in neurology 2025;16:1665835
Frontiers in neurology 2025;16:1665835
circWWC3 enhances the progression of triple-negative breast cancer by interacting with vimentin to regulate the secretion of CSF2.
Wu M, Du Y, Dong Y, Zheng Y, Gu L, Tang X, Yan L, Ji H, Sang Y, Liu F
Frontiers in immunology 2025;16:1665608
Frontiers in immunology 2025;16:1665608
Multi-cohort validation based on coagulation-related genes for predicting prognosis of esophageal squamous cell carcinoma.
Wang R, Zhang W, Li X, Wang H, Ji Y, Zhao J, Song J, Yi Z
Frontiers in immunology 2025;16:1662599
Frontiers in immunology 2025;16:1662599
Thymidine kinase 1 related to Prolif-like T cells promoted GBM through regulation of cell cycle and EMT signals: a comprehensive research based on multi-omics analysis and experimental validation.
Deng W, Chang X, Shang W
Frontiers in immunology 2025;16:1655980
Frontiers in immunology 2025;16:1655980
Identify GDPD3 as a key regulator of epithelial-mesenchymal transition and prostate adenocarcinoma progression via the LPA/LPAR1/AKT axis: transcriptomic and experimental study.
Hao L, Chen X, He T, Wu T, Wen Z, Ji Z, Zheng X, Zheng Q, Zhou Q, He C, Long Q, Sun D
Frontiers in immunology 2025;16:1637325
Frontiers in immunology 2025;16:1637325
Reciprocal activation between M1 macrophages and trophoblasts through CXCL9/STAT1/ZEB1/CCL2 axis promotes recurrent spontaneous abortion.
Yan S, Wang X, Wu Q, Ding J, Qiu H
Frontiers in immunology 2025;16:1629370
Frontiers in immunology 2025;16:1629370
Integrated analysis of single cell and spatial transcriptomics revealed a metastasis mechanism mediated by fatty acid metabolism in lymph nodes of head and neck cancer.
Weng J, Mao J, Li Y, Zhao J, Nong X
Frontiers in immunology 2025;16:1614498
Frontiers in immunology 2025;16:1614498
Quercetin ameliorates epithelial-mesenchymal transition and inflammation by targeting FSTL1 and modulating the NF-κB pathway in pulmonary fibrosis.
Lan Y, Dong C, Wu M, Yuan R, Yang K, Yang Z, Chen Y, Zhang J, Qi B, Lu X
Frontiers in pharmacology 2025;16:1594757
Frontiers in pharmacology 2025;16:1594757
CPLX1 is a novel prognostic biomarker in CRC correlating with immunotherapy resistance and ferroptosis.
Liu C, Liu Q, Lv Y, Chang T, Song S, Ding Y, Zhong J, Liu Y
Frontiers in immunology 2025;16:1589423
Frontiers in immunology 2025;16:1589423
Landscape analysis of matrix metalloproteinases reveals key prognostic markers for prostate cancer.
Li W, Wei X, Yu Y, Tian Y, Yu Q, Qiao J, Tao Y, Li Y, Li T
Frontiers in immunology 2025;16:1582992
Frontiers in immunology 2025;16:1582992
Dissecting the multi-omics landscape of TEAD1 in hepatocellular carcinoma: cycle regulation and metastatic potential.
Huai R, Mao C, Xiong L
Frontiers in immunology 2025;16:1567969
Frontiers in immunology 2025;16:1567969
The miR-941/FOXN4/TGF-β feedback loop induces N2 polarization of neutrophils and enhances tumor progression of lung adenocarcinoma.
Zhang X, Huang X, Zhang X, Lai L, Zhu B, Lin P, Kang Z, Yin D, Tian D, Chen Z, Gao J
Frontiers in immunology 2025;16:1561081
Frontiers in immunology 2025;16:1561081
Prognostic significance and immune infiltration analysis of HMGA2 in endometrial cancer.
Jiang P, Yu J, Zheng Y, Tian C, Tu Y, Gong C, Yu H, Luo Y, Hu Z
Frontiers in immunology 2025;16:1559278
Frontiers in immunology 2025;16:1559278
Enhancing pancreatic cancer treatment: the role of H101 oncolytic virus in irreversible electroporation.
Xi P, Zeng D, Chen M, Jiang L, Zhang Y, Qin D, Yao Z, He C
Frontiers in immunology 2025;16:1546242
Frontiers in immunology 2025;16:1546242
Xanthohumol ameliorates diabetic kidney disease through suppression of renal fibrosis by regulating SNHG10/miR-378b.
Hao J, Li H, Yu W
Frontiers in pharmacology 2025;16:1532517
Frontiers in pharmacology 2025;16:1532517
A comprehensive prognostic and immunological implications of Gremlin 1 in lung adenocarcinoma.
Li H, Zhou Y, Xiao J, Liu F
Frontiers in immunology 2025;16:1529195
Frontiers in immunology 2025;16:1529195
The regulatory role of the circELMOD3-associated ceRNA network in the progression and prognosis of hepatocellular carcinoma.
Li D, Liu M, Lai M, Wang L, Wei L, Wu S, Liang S, Liu S, Zeng X
Frontiers in genetics 2025;16:1521360
Frontiers in genetics 2025;16:1521360
Cyperotundone promotes chemosensitivity of breast cancer via SRSF1.
Li C, Wang L, Liu Z, Wang X, Sun L, Song X, Yu Z
Frontiers in pharmacology 2025;16:1510161
Frontiers in pharmacology 2025;16:1510161
β-lapachone suppresses carcinogenesis of cervical cancer via interaction with AKT1.
Du P, Li Y, Han A, Wang M, Liu J, Piao Y, Chen L
Frontiers in pharmacology 2025;16:1509568
Frontiers in pharmacology 2025;16:1509568
Placental mesenchymal stem cell-derived interleukin-6 promotes neuroblastoma progression.
Liu Y, Li B, Wei H, Xu Y, Liu Y
American journal of cancer research 2025;15(8):3712-3727
American journal of cancer research 2025;15(8):3712-3727
The ubiquitin ligase RCBTB2 regulates aggrephagy and inhibits prostate cancer progression by targeting GPAA1 for degradation.
Mo R, Chi N, Du J, Li X, Guo W, Li H, Wang J, Cai C, Li S, Liu C
American journal of cancer research 2025;15(10):4245-4263
American journal of cancer research 2025;15(10):4245-4263
HPV11 targeting PPARA regulates the autophagy to inhibit the occurrence and development of nasal inverted papilloma.
Zhu G, Zheng L, He W, Chen X, Huang S, Jin M, Zhang Y
Frontiers in oncology 2025;15:1743808
Frontiers in oncology 2025;15:1743808
CMSP suppresses oral squamous cell carcinoma progression by targeting the JAK2/STAT3/c-Myc axis.
Lu Y, Yao M, Wang D, Higuchi D, Lu H, Shang H, Dong B, Zhang J, Jin R, Liu T
Frontiers in oncology 2025;15:1671797
Frontiers in oncology 2025;15:1671797
HOXB7 drives bladder cancer progression via H-Ras/ERK signaling: a potential therapeutic target and prognostic biomarker.
Chen X, Jiang K, Chen K, An Y, Wang Q, Chen X, Zhang P, Zhong Q, Sun F
Frontiers in oncology 2025;15:1645803
Frontiers in oncology 2025;15:1645803
Securinine, a novel alkaloid, regulates cell cycle and EMT in gastric cancer by inducing iron-dependent cell death.
Yuan W, Song H, Shi Y, Han J, Jiao S, Liang S, Xu Y, Jiang Y, Ji Y, Chen Z, Liu L, Xu A, Xu Z
Frontiers in oncology 2025;15:1599680
Frontiers in oncology 2025;15:1599680
MEX3A is a diagnostic, independent prognostic biomarker and a promising therapeutic target in glioblastoma.
Bufalieri F, Armocida D, Cucinotta A, Familiari P, Di Magno L, Serraino A, Adabbo G, Agnoli F, Lospinoso Severini L, Antonelli M, Frati A, Canettieri G, Infante P, Santoro A, D'Angelo L, Di Marcotullio L
Frontiers in oncology 2025;15:1585592
Frontiers in oncology 2025;15:1585592
The anti-inflammatory effects of oridonin in resisting esophageal cancer.
Peng M, Zhang X, Yang L, Liu B
Frontiers in oncology 2025;15:1585057
Frontiers in oncology 2025;15:1585057
Tricellulin facilitates colorectal cancer metastasis through activation of the TGFβ/SMAD2/3 signalling pathway.
Yang W, Cheng R, Qin M, Pan X, Tan Y, Feng K, Zhang J, Huang J
Frontiers in oncology 2025;15:1562976
Frontiers in oncology 2025;15:1562976
Human annexin A5 promotes glioma progression by targeting the MAPK/CD44 pathway.
Liu W, Xiong T, Sun H, Wang M, Zhu J, Li C
Frontiers in oncology 2025;15:1550961
Frontiers in oncology 2025;15:1550961
GART promotes the proliferation and migration of human non-small cell lung cancer cell lines A549 and H1299 by targeting PAICS-Akt-β-catenin pathway.
Chen Z, Ding YH, Zhao MQ, Zhang YJ, Sun MY, Zhang AQ, Qian X, Ji XM
Frontiers in oncology 2025;15:1543463
Frontiers in oncology 2025;15:1543463
Identification and functional characterization of m1A-related genes in colorectal cancer: implications for prognosis, immune infiltration, and therapeutic strategies.
Sun L, Huangfu L, Li F, Yan Y, Kong R, Ji K, Li J
Frontiers in oncology 2025;15:1532602
Frontiers in oncology 2025;15:1532602
Clinical and molecular implications of sex differences in surgically treated early-onset gastric cancer.
Li B, Sun Z, Liu J, Liu D, Xue Z, Tian C, Liu X, Sun J, Zhao J, Li H, Wang X
Gastroenterology report 2025;13:goaf099
Gastroenterology report 2025;13:goaf099
Reduced Wiskott-Aldrich syndrome protein expression in preeclampsia placenta impairs trophoblast syncytialization by modulating syncytin-2 via FAK/β-catenin pathway.
Zhang S, Wang J, Ge Y, Cao P, Bai Z, Shen H, Wang D, Qiao C
Frontiers in cell and developmental biology 2025;13:1678878
Frontiers in cell and developmental biology 2025;13:1678878
Integrative pan-cancer analysis of UCP family and experimental validation identifies UCP2 as a potential therapeutic target for glioma.
Guo W, Chen J, Li S, Zeng X, Wu X
Frontiers in cell and developmental biology 2025;13:1662654
Frontiers in cell and developmental biology 2025;13:1662654
Engineering a 3D wounded skin equivalent to study early inflammatory and regenerative responses in vitro.
Nuwayhid R, Ngoc-Huyen N, Notov D, Langer S, Kurow O
Frontiers in bioengineering and biotechnology 2025;13:1621566
Frontiers in bioengineering and biotechnology 2025;13:1621566
Synchronous neuroendocrine tumor and signet ring cell carcinoma in the stomach: a case report and review of literature.
Han J, Wang Y, Mu H, Liu J
Frontiers in medicine 2025;12:1561231
Frontiers in medicine 2025;12:1561231
Ciprofol exerts anti-tumour effects in hepatocellular carcinoma through the Raf-MEK-ERK signalling pathway.
Chen Y, Shi P, Zhou S, Yu K, Wang Y, Yao F, Zhang R, Liu X, Fang C, Tie X, Li J, Xu J, Xu J, Pan X
Translational gastroenterology and hepatology 2025;10:52
Translational gastroenterology and hepatology 2025;10:52
Phytochemical nanozymes reprogram redox for balanced antimicrobial and regenerative therapy in acute and chronic diabetic wounds.
Pang Y, Amona FM, Chen X, You Y, Sha Z, Liu Z, Li J, Liu Y, Fang X, Chen X
Redox biology 2025 Sep;85:103718
Redox biology 2025 Sep;85:103718
PLEKHF1 Induces Mitochondrial Dysfunction to Inhibit Osteosarcoma Growth and Metastasis.
Wan J, Cai X, Liao Z, Liu Y, Liu Q, Zhang C, Long F
IUBMB life 2025 Sep;77(9):e70048
IUBMB life 2025 Sep;77(9):e70048
Targeting Dlat-Trpv3 pathway by hyperforin elicits non-canonical promotion of adipose thermogenesis as an effective anti-obesity strategy.
Lu S, Jiang Q, Zhou P, Yin L, Wang N, Xu J, Qian Q, Tao M, Yin H, Han L, Gu Y, Gao F, Liu J, Chen S
Journal of advanced research 2025 Sep;75:793-809
Journal of advanced research 2025 Sep;75:793-809
EIF3B‑METTL3 complex promotes cell proliferation, invasion and EGFR/AKT signaling in cervical cancer.
Zhang C, Fan X, Yang J, Zhu P
Oncology reports 2025 Sep;54(3)
Oncology reports 2025 Sep;54(3)
Kaempferol Suppresses Mesothelial-Mesenchymal Transition and Attenuates Postoperative Peritoneal Adhesions by Blocking the TNF-α/COX2 Signalling Pathway.
Zhang L, Li G, Ren Y, Sun Y, Deng K, Cai L, Li E, Shen T, Li X, Zhou C
Clinical and experimental pharmacology & physiology 2025 Sep;52(9):e70061
Clinical and experimental pharmacology & physiology 2025 Sep;52(9):e70061
Gallium maltolate and cisplatin co-treatment effectively targets triple-negative breast cancer in spheroid and mouse models.
Yang YW, Hsieh YC, Liu CY, Pan CK, Pan ZY, Lo KY
Toxicology and applied pharmacology 2025 Sep;502:117460
Toxicology and applied pharmacology 2025 Sep;502:117460
Study of the Reciprocal Interaction Between Tumor Cells and Macrophages Based on the Biomimic Microfluidic Device.
Jin S, Wu Q, Chang S, Zeng S, Yin J, Ma H
Electrophoresis 2025 Sep;46(18):1388-1396
Electrophoresis 2025 Sep;46(18):1388-1396
METTL3 Mediates Wnt/β-Catenin Pathway in Epithelial-Mesenchymal Transition of 16HBE Cells Induced by Beryllium Sulphate.
Yan C, Li G, Huang L, Zhang Z
Journal of applied toxicology : JAT 2025 Sep;45(9):1787-1797
Journal of applied toxicology : JAT 2025 Sep;45(9):1787-1797
Leukemia Inhibitory Factor via JAK-STAT Signaling Drives Beryllium Sulfate-Induced Epithelial-Mesenchymal Transition in 16HBE Cells.
Li Y, Sun Z, Tong Y, Yan C, Huang L, Zhang Z
Journal of applied toxicology : JAT 2025 Sep;45(9):1720-1729
Journal of applied toxicology : JAT 2025 Sep;45(9):1720-1729
Up-regulation of NGEF via the BRAF(V600E) /ERK/AP1 pathway enhances invasion and migration abilities of BRAF(V600E)-mutant thyroid cancer.
Fu Z, Wang Y, Wang CJ, Yu Z, Chen JQ
Biochemistry and biophysics reports 2025 Sep;43:102164
Biochemistry and biophysics reports 2025 Sep;43:102164
Mechanism of SC targeting RhoA regulation and its potential value in gastric cancer therapy.
Ma H, Jiang P, Ma R, Zhao J, Wang Q, Xing Y, Cao C, Su Z
Biochemistry and biophysics reports 2025 Sep;43:102158
Biochemistry and biophysics reports 2025 Sep;43:102158
p62/SQSTM1 impairs immunotherapy in lung adenocarcinoma by suppressing immune infiltration and peripheral immune response.
Li H, Qin H, Xin Q, Gao J, Li S, Thomas AM, Li N, Xu L, Li M
Biochemistry and biophysics reports 2025 Sep;43:102139
Biochemistry and biophysics reports 2025 Sep;43:102139
SPOCK2 promotes the invasion and migration of ovarian cancer cells through FAK signaling pathway.
Zheng X, Wu H, Zhu W
Journal of gynecologic oncology 2025 Sep;36(5):e98
Journal of gynecologic oncology 2025 Sep;36(5):e98
Tumor-derived exosome-based microRNA-206 delivery system as dual modulators of the immune microenvironment and gut microbiota for colorectal cancer therapy.
Tian J, Liu M, Yang X, Wang T, Zhou R, Liu J, Ma B, Su C, Duan X
International journal of biological macromolecules 2025 Sep;321(Pt 4):146489
International journal of biological macromolecules 2025 Sep;321(Pt 4):146489
20-Acetylsinularolide B (ASB) From Lobophytum crassum Exhibits Anticancer Activity In Vitro Through IGF1R/PI3K/AKT/mTOR Pathway.
Chang Y, Shen S, Zhang L, Zeng J, Sun J, Guo YW, Su MZ
Chemistry & biodiversity 2025 Sep;22(9):e202500114
Chemistry & biodiversity 2025 Sep;22(9):e202500114
Chronic exposure to B[a]P induces malignant transformation of breast epithelial cells through the mechanism via TGF-β signaling pathway.
Tang Y, Feng Z, Ma C, Jang N, Chen X, He Y, Martin FL, Liu H, Pang W
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Sep;203:115574
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2025 Sep;203:115574
Ganoderic acid T, a novel activator of pyruvate carboxylase, exhibits potent anti-liver cancer activity.
Lei B, Zhang M, Shi X, Feng N, Yin J, Dong R, Xie C, Zhu Y, Zhong JJ, Ni B
Metabolism: clinical and experimental 2025 Sep;170:156321
Metabolism: clinical and experimental 2025 Sep;170:156321
Shenling Tongqiao powder targets TGF-β1/Smad-Wnt/β-catenin axis to suppress epithelial-mesenchymal transition in chronic rhinosinusitis.
Liu K, Zeng H, Zhu X, Deng H, Deng W, Li S, Zhu Y, Bin J, Lu S, Wu W, Wu Q, Liao J, Hu G, Chang W, Ying Y, Wang Y, Zhu Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157065
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157065
Ginger-processed Magnoliae Officinalis Cortex ameliorates ovalbumin-induced asthma by alleviating inflammation via the gut-lung axis.
Li J, Hu J, Zhuo D, Yang L, Wang L, Yang B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156971
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156971
Peptide-Enhanced Bioactive Hydrogel Combined with Photodynamic-Phage Synergistic Antibacterial Therapy System Accelerates Infected Wound Healing.
Quan L, Xin Y, Zhang Z, Zhou C, Ao Q
Advanced healthcare materials 2025 Sep;14(24):e2500875
Advanced healthcare materials 2025 Sep;14(24):e2500875
Zinc Alleviates Gut Barrier Dysfunction by Promoting the Methylation of AKT.
Cai C, Zheng Y, Sun B, Wang G, Li P, Geng H, Li R, Zhu M, Zhu Y, Feng D, Chen L, Chu G, Deng L, Qiao S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(33):e08280
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(33):e08280
Suppressed autophagy of thymic cells promotes apoptosis and thymic atrophy in COPD.
He S, Yang Z, Xie L
Heart & lung : the journal of critical care 2025 Sep-Oct;73:180-189
Heart & lung : the journal of critical care 2025 Sep-Oct;73:180-189
A Novel Nuclear-Localized Micropeptide, MP60, Promotes Hepatocellular Carcinoma Progression via the Epithelial-Mesenchymal Transition.
Li C, Hong X, Setrerrahmane S, Sun X, Zhang X, Xu H
Cancers 2025 Sep 7;17(17)
Cancers 2025 Sep 7;17(17)
Lithocholic acid ameliorates ulcerative colitis via the PXR/TLR4/NF-κB/NLRP3 signaling pathway and gut microbiota modulation.
Liu Y, Gao J, Chen L, Chen Y, Jiang J, Chen H, Ma L
Cellular and molecular life sciences : CMLS 2025 Sep 4;82(1):336
Cellular and molecular life sciences : CMLS 2025 Sep 4;82(1):336
LncRNA LOXL1-AS1 promotes ovarian cancer progression by enhanced BRIP1 mRNA stability.
Wan S, Su C, Ding J, Liu J, He L, Liu L, Peng Q, Ni G, Zhu W
Medical oncology (Northwood, London, England) 2025 Sep 30;42(11):504
Medical oncology (Northwood, London, England) 2025 Sep 30;42(11):504
Development of Primary Colon and Duodenal Tumor Cultures from the Apc-mutant Pirc Rat for Screening Preventive Agents.
Muhsin A, Neja S, Mohan N, Kapoor S, Perez JET, Dashwood WM, Rashid A, Dashwood R, Rajendran P
Journal of cancer prevention 2025 Sep 30;30(3):166-176
Journal of cancer prevention 2025 Sep 30;30(3):166-176
NRF2 promotes the migration of ovarian cancer cell lines by targeting TAGLN mediated epithelial-mesenchymal transition.
Wang H, Zhang P, Cheng Q, Bao L
Journal of ovarian research 2025 Sep 30;18(1):213
Journal of ovarian research 2025 Sep 30;18(1):213
Circular RNA hsa_circ_0006522 correlates with unfavorable prognosis and promotes the proliferative, migrative, and invasive abilities of breast cancer cells.
Wang X, Zhang P, Bai Z, Meng L, Zheng Y, Sang M, Geng C
Translational cancer research 2025 Sep 30;14(9):5823-5837
Translational cancer research 2025 Sep 30;14(9):5823-5837
C1orf116 inhibits acquired resistance to EGFR inhibitors in EGFR mutant lung adenocarcinoma by suppressing the ATM/ATR pathways.
Wang F, Lu C, Yang X, Wei X, Luo W, Wu L, Yan H, Chen Z, Zhou Q
Translational lung cancer research 2025 Sep 30;14(9):3796-3810
Translational lung cancer research 2025 Sep 30;14(9):3796-3810
CHD4 drives gastric cancer metastasis via MYH9/GSK3β/β-catenin axis and WNT/EMT pathway activation.
Shi Y, Zhao Z, Zhou S, Zhou Z, Huang Z, Zhou Z, Zhang C
Cancer letters 2025 Sep 28;628:217813
Cancer letters 2025 Sep 28;628:217813
LCN2-positive alveolar type II cells promote silica-induced pulmonary fibrosis via STAT3-TGF-β1-Smad3-mediated signaling.
Xie Z, Li X, Zhang M, Cao H, Wang F, Yan R, Ye H, Mu M, Wang J, Wang F, Tao X
Toxicology and applied pharmacology 2025 Sep 27;505:117579
Toxicology and applied pharmacology 2025 Sep 27;505:117579
Overexpression of alcohol dehydrogenase 1 A inhibits the progress of triple negative breast cancer via Wnt/β-catenin signaling.
Su L, Qiao C, Luo J, Zhu B, Liu Y
Scientific reports 2025 Sep 26;15(1):32986
Scientific reports 2025 Sep 26;15(1):32986
EMB is essential for enteric nervous system development mediated by PI3K signaling.
Li Z, Zhuansun D, Meng X, Yang H, Xiao J, Chen Y, Wang J, Yu X, Li Z, You J, Chen X, Feng C, Wu L, Chu X, Duan W, Wang K, Li Z, Tou J, Yu L, Tang W, Liu Y, Jiang X, Ren H, Yu M, Yin Q, Liu X, Xu Z, Wu D, Jiao C, Yu D, Wu X, Zhu T, Yang J, Xiang L, Wang J, Wang Q, Zhou B, Wang D, Chen K, Mao H, Wang B, Zhan J, Wang CY, Zeng W, Chen F, Xiong B, Feng J
Genome medicine 2025 Sep 25;17(1):102
Genome medicine 2025 Sep 25;17(1):102
TAIII Suppresses the Growth of T790M-Mutant Non-Small-Cell Lung Cancer by Targeting the EGFR/ERK Signaling Pathway.
Gao S, Luan Y, Yu X, Wang L, Huang X, Yang J, Liu W
Pharmaceuticals (Basel, Switzerland) 2025 Sep 24;18(10)
Pharmaceuticals (Basel, Switzerland) 2025 Sep 24;18(10)
JMJD6-driven epigenetic activation of COL4A2 reprograms glioblastoma vascularization via integrin α1β1-dependent PI3K/MAPK signaling.
Wu Y, Wu Y, Xia S, Lian H, Lou Y, Wang LJ
Acta neuropathologica communications 2025 Sep 24;13(1):194
Acta neuropathologica communications 2025 Sep 24;13(1):194
Orthosteric-allosteric dual inhibitors of PI5P4Kγ with potent antitumor activity in non-small cell lung cancer.
Xiong L, Tang 唐磊 L, Zhao W, Wang R, Cheng C, Wang D, Xu Y, Tang 汤磊 L, Fan Y
Journal of advanced research 2025 Sep 22;
Journal of advanced research 2025 Sep 22;
Caspase-9 activates β-catenin signaling to promote pulmonary fibrosis.
Wang J, Qing B, Gu L, Chen H, Chen Y, Tang Y, Ge Z, Hu R, Yuan Y, Xia Z
Journal of translational medicine 2025 Sep 2;23(1):986
Journal of translational medicine 2025 Sep 2;23(1):986
Biphasic Adaptations of Gastric Epithelial Cells in Chronic H. pylori Infection from Stress to Tolerance.
Zhang X, He Y, Zhang X, Liang Z, Wang W, Da Z, Lv J, Guo M, Huo X, Liu X, Lu J, Cao L, Du X, Ge Z, Chen Z, Lu X, Zhang J, Li C
International journal of molecular sciences 2025 Sep 16;26(18)
International journal of molecular sciences 2025 Sep 16;26(18)
Downregulation of HDAC9 Alleviates Autophagy Dysfunction by Inducing Acetylation of ATG4B in Metabolic Dysfunction-Associated Steatotic Liver Disease.
Ma XH, Liu GP, Liu L, Dou ZY, He X, Chen X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 15;39(17):e70991
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Sep 15;39(17):e70991
Zearalenone at environmental levels promoted ER- positive breast cancer cell lines through the hedgehog pathway.
Xu L, Zhou H, Zhong Y, Zhao L, Qian J, Ding L, Chang X, Kassotis C, Cui Q
Ecotoxicology and environmental safety 2025 Sep 15;303:118813
Ecotoxicology and environmental safety 2025 Sep 15;303:118813
Inhibition of GRK2 mitigates renal fibrosis via oxidative stress pathway.
Cheng J, Jiang X, Deng Q, Ni L, Lin W, Cao W, Ren P, Xu B, Wang Q, Kuai J, Wu Y, Wei W, Wang C
European journal of pharmacology 2025 Sep 15;1003:177887
European journal of pharmacology 2025 Sep 15;1003:177887
CENPA-driven transcriptional activation of ECT2 enhances EGFR inhibitor resistance in lung adenocarcinoma.
Zhao M, Hang Y, Zheng H, Yang L, Yang M, Chen G, Wu G, Kong M, Wang N
Biochemical and biophysical research communications 2025 Sep 1;777:152287
Biochemical and biophysical research communications 2025 Sep 1;777:152287
NudCL2 suppresses pancreatic cancer progression by inhibiting SLC7A11-mediated EMT and metastasis.
Feng J, Yang M, Lin R, Shang K, Sun M, Guo Z, Wang Y, Zhou T, Yang F, Yang Y
Experimental cell research 2025 Sep 1;452(1):114730
Experimental cell research 2025 Sep 1;452(1):114730
Dietary addition of magnesium hydride nanoparticles: a breakthrough in combating high-fat diet-induced chronic kidney disease.
Lu H, Chen W, Ying Y, Gu D, Li R, Li X, Cheng J, Sun X, Zhang Y, Liu W, Shen H
Medical gas research 2025 Sep 1;15(3):374-382
Medical gas research 2025 Sep 1;15(3):374-382
TKT regulates the pentose phosphate pathway via RBKS to promote epithelial-mesenchymal transition during AML progression.
Li F, Liu J, Geng Y, Liu L, Li J, Pu L, Hu Z, Yang Y
Journal of bioenergetics and biomembranes 2025 Oct;57(4-5):289-302
Journal of bioenergetics and biomembranes 2025 Oct;57(4-5):289-302
Inhibition of SLC3A2 Deletion-Mediated Ferroptosis by Bone Marrow Stromal Cells to Alleviate Inflammation and Fibrosis in Diabetic Kidney Disease.
Fan Y, Li YL, Huang LL, Yang J, Hou YY, Bai YH
Inflammation 2025 Oct;48(5):3219-3234
Inflammation 2025 Oct;48(5):3219-3234
Dapagliflozin ameliorates high glucose-induced epithelial-mesenchymal transition via up-regulating ACE2 mediated by EZH2 in diabetic nephropathy.
Wang S, Zhang X, Chong N, Chen D, Shu J, Wang R, Wang Q, Xu Y
Journal of endocrinological investigation 2025 Oct;48(10):2499-2509
Journal of endocrinological investigation 2025 Oct;48(10):2499-2509
LGI3 promotes the progression of TFE3-rearranged renal cell carcinoma through GEMIN6/AURKB axis.
Liu J, Feng H, Xiong Z, Cao S, Cai T, Wei W, Tao W, Zhang X, Ma X, Li X
Oncogene 2025 Oct;44(39):3729-3740
Oncogene 2025 Oct;44(39):3729-3740
Kaempferide Inhibits the Proliferation and Invasion and Induces Ferroptosis in Melanoma by Inactivating Wnt/β-Catenin Pathway.
Xu Y, Zhao R, Huang Z, Zhang Y, Yang R, Zhang J
Journal of biochemical and molecular toxicology 2025 Oct;39(10):e70535
Journal of biochemical and molecular toxicology 2025 Oct;39(10):e70535
Resveratrol glycoside inhibits NLRP3/IL-1β/NF-κB to alleviate peritoneal fibrosis in peritoneal dialysis.
Liu K, Huang Y, Xiao W, Liao J, Ouyang S, Liang Y, Fu J
Clinical and experimental nephrology 2025 Oct;29(10):1331-1341
Clinical and experimental nephrology 2025 Oct;29(10):1331-1341
Profibrotic impact of PAD4-driven macrophage extracellular traps in ulcerative colitis.
Wang Z, Shi R, Shi Y, Sun T, Shen Y, Wu C, Yang Y, Fan H, Wu J
Pharmacological research 2025 Oct;220:107933
Pharmacological research 2025 Oct;220:107933
Phosphodiesterase 12 facilitates the growth and metastatic capabilities of gastric cancer cells by activating the TCAF2/JAK2/STAT3 axis.
Liu YJ, Song HX, Li JH, Wang XY, Nie XF, Zhang LN
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167973
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167973
Small proline-rich protein 2A drives epithelial remodeling in eosinophilic chronic rhinosinusitis with nasal polyps via SAA2 upregulation.
Xie S, Jiang S, Yuan X, Liu L, Wu M, Gu W, Zhang H, Xie Z, Jiang W, Gao P
The Journal of allergy and clinical immunology 2025 Oct;156(4):1038-1052.e5
The Journal of allergy and clinical immunology 2025 Oct;156(4):1038-1052.e5
KIF18B drives the malignant progression of gliomas by activating the Notch pathway.
Zhang L, Li F, Zhang L, Zhou Y, Liu Y, Liu J, Cheng Y, Shu J, Zhao H, Wei Y
Cellular signalling 2025 Oct;134:111888
Cellular signalling 2025 Oct;134:111888
Glucose Deprivation-Induced Disulfidptosis via the SLC7A11-INF2 Axis: Pan-Cancer Prognostic Exploration and Therapeutic Validation.
Song Z, Yao Q, Huang L, Cui D, Xie J, Wu L, Huang J, Zhai B, Liu D, Xu X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(39):e08556
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(39):e08556
Discovery of Natural Compound α-Hederin via Large-Scale Screening as a Targeted JAK/STAT3 Inhibitor for Ovarian Cancer Therapy.
Wang J, He P, Liu C, Chen X, Tan Y, Qu R, Zhang Y, Li Z, Yin T, Yin Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(38):e17278
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(38):e17278
Hsa_circ_0005325 Regulates the Proliferation, Apoptosis, Colony Formation, Migration, and Angiogenesis-Promoting Behavior of Oral Squamous Cell Carcinoma Cells Through the miR-433-3p/HMGA2 Axis.
Lin Z, Fu Y, Mao L, Yan H, Liu W, Tang X
Clinical and experimental dental research 2025 Oct;11(5):e70208
Clinical and experimental dental research 2025 Oct;11(5):e70208
Geniposide alleviates kidney fibrosis by targeting STAT3-HK2-mediated glycolysis.
Shi R, Liu MQ, Xiao JP, Zhu YK, Zhu JX, Zhao WM, Wang ZJ, Zhu YY, Li XL, Wang XR, Wang RF, Wang DG
BMC complementary medicine and therapies 2025 Oct 9;25(1):365
BMC complementary medicine and therapies 2025 Oct 9;25(1):365
Oncogenic Role of SAMD4B in Breast Cancer Progression by Activating Wnt/β-Catenin Pathway.
Li JH, Wang XY, Song HX, Nie XF, Zhang LN
Biomolecules 2025 Oct 7;15(10)
Biomolecules 2025 Oct 7;15(10)
Hypermethylation-mediated HNF4A silencing by Helicobacter pylori infection drives gastric cancer by disrupting epithelial cell polarity and activating EMT signaling.
Li D, Zhou Z, Li X, Guo Q, Yuan L, Zhang X, Zhai L, Xia L, Leng W, Qin S
Cell death & disease 2025 Oct 6;16(1):688
Cell death & disease 2025 Oct 6;16(1):688
KAT2A-H3K79succ-Mediated SH2B3 Upregulation Promotes TNBC Metastasis Through Diminishing the Ubiquitin-Dependent Degradation of Vimentin.
Shi X, Hao R, Yang Z, Wang X, Lu Y, Wang X, Ji H, Ma S, Liu X, Hu J, Qi Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Oct 31;39(20):e71140
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Oct 31;39(20):e71140
miR-196a-5p promotes the proliferation, migration, and invasion of esophageal squamous cell carcinoma by targeting LIFR.
Zhang J, Liang F, Wang W, Qin Y, Hu X
Cancer cell international 2025 Oct 31;25(1):384
Cancer cell international 2025 Oct 31;25(1):384
FUT8 promotes HDM-induced glycolysis, epithelial-mesenchymal transition and inflammation in bronchial epithelial cells by inducing N-glycosylation modification of GLUT1.
Huang W, Yuan X, Lu J, Zhang S, Sun Y, Hang Y, Shen Y, Chen M, Li J, Huang J, Zhang W, Li L
Biochemical and biophysical research communications 2025 Oct 30;786:152721
Biochemical and biophysical research communications 2025 Oct 30;786:152721
RPL22L1-Myc positive feedback loop drives lung adenocarcinoma progression.
Wu Y, Zhu Y, Jiang R, Gu W, Lu L, Yao N, Du B, Lai J
Cancer cell international 2025 Oct 3;25(1):333
Cancer cell international 2025 Oct 3;25(1):333
α-hederin inhibits cervical cancer progression by inducing DNA damage-dependent cell cycle blockade and apoptosis.
Song Y, Qin H, Huang S, Wang J, Huang Y, Lin Z, Yang F, Zhang X, Wang R, Wang J
BMC cancer 2025 Oct 3;25(1):1503
BMC cancer 2025 Oct 3;25(1):1503
Sorcin regulates alveolarization and airway tissue remodeling during lung morphogenesis.
Tito C, De Angelis L, Iaiza A, Abbinantefina AP, Benedetti A, Mazzanti G, Petrozza V, Lauriola M, Tamagnone L, Ilari A, Masciarelli S, Colotti G, Fazi F
Cellular and molecular life sciences : CMLS 2025 Oct 28;82(1):367
Cellular and molecular life sciences : CMLS 2025 Oct 28;82(1):367
Macrophage-derived exosomes carrying miR-30a-5p alleviates IL-13/IL4-induced epithelial-mesenchymal transition in mouse bronchial epithelial cells via Runx1.
Wu B, Li D, Wang Y, Xu J, Li L, Wang M
BMC pulmonary medicine 2025 Oct 28;25(1):496
BMC pulmonary medicine 2025 Oct 28;25(1):496
Fusobacterium nucleatum increases CTGF expression through TLR2-YAP signaling axis in cancer-associated fibroblasts, thereby promoting colorectal cancer progression.
Wang H, Lin B, Wang Z, Yang J, Guo X, Li W, Li B, Shi S, Zhou Y, Han R, Wei Y, Liu Y
Cancer cell international 2025 Oct 28;25(1):381
Cancer cell international 2025 Oct 28;25(1):381
Mesenchymal stem cells inhibit mitochondrial fission by upregulating armadillo repeat containing 1, ameliorating oxidative stress in renal fibrosis.
Li T, Guo C, Liu Q, Jing F, Zhao M, Xiong H, Li C, Zhang W, Chen B
Stem cell research & therapy 2025 Oct 28;16(1):584
Stem cell research & therapy 2025 Oct 28;16(1):584
The deubiquitination enzyme USP14 promotes the tumourigenesis of gastric cancer by enhancing c-MYC nuclear translocation through deubiquitination of KPNA2.
Li J, Tang H, Chang H, Du Y, Du L, Zhao E
Cell death & disease 2025 Oct 21;16(1):737
Cell death & disease 2025 Oct 21;16(1):737
Pan-cancer analysis of role of LOXL4 and experiment validation in osteosarcoma.
Chen W, Xie F, Lv J, Huang D, Zhong R, Wen Z, Sun J, Zheng S, Liu W, Zhong H, Huang S
Discover oncology 2025 Oct 21;16(1):1926
Discover oncology 2025 Oct 21;16(1):1926
PTPN2 acts as a tumor suppressor and therapeutic target in ovarian cancer.
Sun X, Zhang W, Wang H, Hao J, Shi W, Lei P, Wei G, Liu Y, Xu C, Li L, Yu L, Zhang DL
Biochemical and biophysical research communications 2025 Oct 20;785:152704
Biochemical and biophysical research communications 2025 Oct 20;785:152704
A Cell-Potent Bisubstrate Inhibitor to Probe NatD Acetyltransferase Activity.
Ho YH, Seipp EK, Larndate T, Huang R
ACS chemical biology 2025 Oct 17;20(10):2512-2520
ACS chemical biology 2025 Oct 17;20(10):2512-2520
Functional metabolomics revealed pyroglutamic acid may play a key role in idiopathic pulmonary fibrosis.
Wen Y, Nie JH, Qin XM, Li ZY
Journal of pharmaceutical and biomedical analysis 2025 Oct 15;264:116967
Journal of pharmaceutical and biomedical analysis 2025 Oct 15;264:116967
Nephroprotective mechanism of Kunkui Baoshen decoction in diabetic kidney disease: Targeting the HERC2/NCOA4-mediated autophagy-dependent ferroptosis pathway.
Song SY, Shan CC, Zhou PP, Xu WL, Tan Y, Zhou XQ, Huang LJ, Yan QH, Yu JY
World journal of diabetes 2025 Oct 15;16(10):109568
World journal of diabetes 2025 Oct 15;16(10):109568
PDLIM4 drives gastric cancer malignant progression and cisplatin resistance by inhibiting HSP70 ubiquitination and degradation via competitive interaction with STUB1.
Zhu C, Chen M, Fan L, Wang Y, Liu M, Kang G, Yin F, Tang H, He Y, Zhang S, Zeng L, Liu W, Yu K, Le A
Journal of nanobiotechnology 2025 Oct 11;23(1):661
Journal of nanobiotechnology 2025 Oct 11;23(1):661
Cedrol impedes lung cancer metastasis by reducing tumor-associated macrophage polarization mediated by MYC-driven aerobic glycolysis.
Li Q, Liu Y, Zhang L, Zheng Y, Feng X, Wang Y
Human cell 2025 Oct 10;38(6):177
Human cell 2025 Oct 10;38(6):177
Cigarette smoke extract promotes metastasis and oxaliplatin resistance in colon adenocarcinoma through GDF15/ERBB2/AKT pathway.
Jiang W, Wang Y, Wang WJ, Zhou BC, Hu XS, Xu AM
European journal of medical research 2025 Oct 10;30(1):958
European journal of medical research 2025 Oct 10;30(1):958
Centromere protein I facilitates breast cancer tumorigenesis and disease progression through modulation of Wnt/β-Catenin signaling.
Wu C, Zhou Y, Mu Y, Cheng Y, Xu W, Huang M, Xu J, Li M, Gu J, Meng X, Qian D
Cancer cell international 2025 Oct 10;25(1):348
Cancer cell international 2025 Oct 10;25(1):348
Mechanism of silica nanoparticles induced pulmonary epithelial-mesenchymal transition mediated by exosomal HNRNPAB.
Zhao X, Pan Y, Yan G, Yu Y, Song Y
Ecotoxicology and environmental safety 2025 Oct 1;304:119162
Ecotoxicology and environmental safety 2025 Oct 1;304:119162
PARP1 promoter hypermethylation promotes arsenic-induced skin damage by driving telomere dysfunction-mediated keratinocyte senescence.
Yang L, Wang W, Zhang A
Ecotoxicology and environmental safety 2025 Oct 1;304:119108
Ecotoxicology and environmental safety 2025 Oct 1;304:119108
AHCTF1 Functions as an Oncogenic Factor and Promotes Tumor Progression in Hepatocellular Carcinoma.
Liu H, Zhou W, Li C, Shen H, Zhang N
Digestive diseases and sciences 2025 Nov;70(11):3743-3754
Digestive diseases and sciences 2025 Nov;70(11):3743-3754
Harnessing TP73‑targeted nintedanib: A novel strategy to halt triple‑negative breast cancer via p53‑PPARα/PI3K‑Akt pathway suppression.
Zou X, Li S, Huang S, Niu R, Liu G, Wang Z
International journal of oncology 2025 Nov;67(5)
International journal of oncology 2025 Nov;67(5)
EHBMT, a method for visualizing tumor evolution, identifies a surge in gastric cancer with hybrid epithelial-mesenchymal phenotypes due to an inflammatory microenvironment.
Li D, Zhou Z, Hui Y, Yu H, Ren T, Zhai L, Li X, Yuan L, Xia L, Leng W, Qin S
Experimental & molecular medicine 2025 Nov;57(11):2440-2457
Experimental & molecular medicine 2025 Nov;57(11):2440-2457
Mitochondrial dysfunction-associated cellular senescence is partially involved in bleomycin-induced pulmonary fibrosis in mice.
Yao YX, Lu X, Li Z, Liao HY, Liu ZB, Zhao H, Wang H, Xu DX, Tan ZX
Toxicology and applied pharmacology 2025 Nov;504:117524
Toxicology and applied pharmacology 2025 Nov;504:117524
METTL16 promotes progression of clear cell renal cell carcinoma via up-regulating N6-methyladenosine modification of KLK4 mRNA.
Fan B, Niu Y, Li T, Chen H, Zeng K, Li S, Ma Y
Molecular and cellular biochemistry 2025 Nov;480(11):5741-5751
Molecular and cellular biochemistry 2025 Nov;480(11):5741-5751
Astragaloside IV Alleviates Cisplatin Chemotherapy-Induced Nephrotoxicity via Modulation of Nrf2/HO-1/NF-κB Pathway and Reversal of EMT Process.
Ding X, Han X, Zhang Y, Zhang Y, Li F, Wang J
Journal of biochemical and molecular toxicology 2025 Nov;39(11):e70565
Journal of biochemical and molecular toxicology 2025 Nov;39(11):e70565
Integrative multi-omics analysis and experimental validation reveal centromere protein W as a potential therapeutic target and predictive biomarker in renal clear cell carcinoma.
Li J, Huang R, Tian J, Xu Z, Zhang Y, Wang X, Zhang P, Ling J, Chao L, Hu H
International journal of biological macromolecules 2025 Nov;330(Pt 3):148234
International journal of biological macromolecules 2025 Nov;330(Pt 3):148234
Targeting MTPN sensitizes pancreatic cancer of wild-type BRCA1/2 to Cisplatin-based chemotherapy.
Wang Z, Huang X, Bai T, Jin Y, Gong T, Wu W, Kouken B, Wang Q, Wang L
Cancer gene therapy 2025 Nov;32(11):1245-1258
Cancer gene therapy 2025 Nov;32(11):1245-1258
Galectin-9 promotes colon cancer development by polarizing macrophages toward the M2 phenotype.
Zhang J, Xu Y, Han X, Gao Y, Wei Z, Sun X
Cancer genetics 2025 Nov;298-299:141-150
Cancer genetics 2025 Nov;298-299:141-150
METTL3/IGF2BP2 stabilizes IQGAP3 via m6A modification to drive HCC metastasis through TGF-β/Smad signaling and EMT.
Pan D, Zhang H, Zhou J, He S, Yuan G
Pathology, research and practice 2025 Nov;275:156228
Pathology, research and practice 2025 Nov;275:156228
UBE2O-mediated ubiquitylation directs cytoplasmic CTNNA1 to promote cell-to-ECM adhesions.
Xiang D, Wu W, Shi R, Tang X, Zhang X
EMBO reports 2025 Nov;26(22):5431-5458
EMBO reports 2025 Nov;26(22):5431-5458
A Shikonin Derivative Induces Excessive Autophagy in Pancreatic Cancer Cells.
Cao Q, Zhou Y, Xiong L, Sheng M, Peng Y, Huang J, Zhang S
Chemistry & biodiversity 2025 Nov;22(11):e00721
Chemistry & biodiversity 2025 Nov;22(11):e00721
TRIB3 promotes endometrial cancer progression through interacting with E2F1 and enhancing PKM2-mediated tumor glycolysis.
Geng F, Wang Y, Cui G, Fan M
Gynecologic oncology 2025 Nov;202:41-52
Gynecologic oncology 2025 Nov;202:41-52
Identification and validation of BCL11A as a neural and immune vulnerability factor in pancreatic adenocarcinoma.
Chen A, Wang J, Yang J, Wang Y, Wu C, Yang H, Fan Y, Gao Q, Hu Y, Li X, Zou X
Biochimica et biophysica acta. Molecular basis of disease 2025 Nov;1871(8):167988
Biochimica et biophysica acta. Molecular basis of disease 2025 Nov;1871(8):167988
A novel off-liver sinusoidal progenitor cells in supporting transplantable bioliver engineering.
Lai J, Hu D, Yan M, Chen Q, Shi H, Yang Q, Ding M, Li L, Zhang H, Bai L
Biomaterials advances 2025 Nov;176:214358
Biomaterials advances 2025 Nov;176:214358
Protective role of orphan G protein-coupled receptor GPR35 in the pathogenesis of colitis through regulating epithelial barrier function and immune responses.
Tokuyama K, Yasuda H, Saito M, Hayashi S, Kato S
Journal of pharmacological sciences 2025 Nov;159(3):191-201
Journal of pharmacological sciences 2025 Nov;159(3):191-201
Rosmarinic acid induces ferroptosis in colon cancer: insights from AKR1C3/PTGS2 pathway and mitochondrial dysfunction.
Tang J, Zhang J, Chen H, Wang Z, Wu L, Xue P, Yang R, Peng W, Zeng P
3 Biotech 2025 Nov;15(11):374
3 Biotech 2025 Nov;15(11):374
MicroRNA-93-5p alleviates uric acid-induced fibrosis in renal tubular epithelial cells by regulating the SMAD5/Id2 signaling pathway.
Lu X, Ma C, Li D, Yang J, Sun Y, Liu B, Zhao B, Li H
Cellular signalling 2025 Nov;135:112081
Cellular signalling 2025 Nov;135:112081
N-glycosylation stabilized TNFAIP6 promotes ovarian cancer metastasis by activating the PI3K-AKT signaling pathway.
Liu X, Ji D, Wen Z, Tang Q, Chen Y
Cellular signalling 2025 Nov;135:112013
Cellular signalling 2025 Nov;135:112013
CX-5461 inhibits cell proliferation and induces ferroptosis of colorectal cancer cells by inactivating Nrf2 pathway.
Chang X, Zhang Y, Wang Q, Yang W, Zhang R, Cong X, Xiao W, Piao J, Lin Z, Jin A
Cellular signalling 2025 Nov;135:111998
Cellular signalling 2025 Nov;135:111998
The E3 ubiquitin ligase TRIM31 enhances the progression of esophageal cancer through the ubiquitination of BBOX1.
Ge L, Sun M, Xu D, Sun G
Cellular signalling 2025 Nov;135:111975
Cellular signalling 2025 Nov;135:111975
Aberrant PJA2-CHRM3 signaling creates a therapeutic vulnerability in gastric tumor.
Li L, Yin J, Zhang L, Liu W, Niu Y, Wang L, Zhao J, Gu Y, Wang Z, Liang D, Fu G, Hua G, Wang X, Huang L
British journal of cancer 2025 Nov;133(8):1122-1136
British journal of cancer 2025 Nov;133(8):1122-1136
RAB26 promotes prostate cancer progression via the MAPK/ERK-TWIST1 signaling axis.
Wang H, Liang S, Du X, Zhao G, Bai Y, Li J, Xu H, Peng S, Yuan Y, Tang W
Genes & diseases 2025 Nov;12(6):101689
Genes & diseases 2025 Nov;12(6):101689
Multi-Omics and Molecular Dynamics Analysis for Biomarker Discovery in Chronic Rhinosinusitis With Nasal Polyps.
Guo Q, Qiao X, Huang S, Wen X, Chen Z, Dong D, Zhao Y
Chemical biology & drug design 2025 Nov;106(5):e70202
Chemical biology & drug design 2025 Nov;106(5):e70202
Effects of fibroblasts-derived exosomal FAP in regulating EMT in epithelial cells from chronic rhinosinusitis.
Shen LF, Fu ZM, Chen HH
Brazilian journal of otorhinolaryngology 2025 Nov-Dec;91(6):101703
Brazilian journal of otorhinolaryngology 2025 Nov-Dec;91(6):101703
P2Y6 receptor inhibition arrests tumor cell progression in a mouse lymphoma model.
Ghimeray K, Sharma S, Rahman MM, Kundu S, Akundi RS
Nucleosides, nucleotides & nucleic acids 2025 Nov 7;:1-19
Nucleosides, nucleotides & nucleic acids 2025 Nov 7;:1-19
Genome edited intestine liver on a chip system for integrated intestinal hepatic drug absorption and metabolism evaluation.
Negoro R, Deguchi S, Yamazaki D, Takayama K, Fujita T
Scientific reports 2025 Nov 4;15(1):38609
Scientific reports 2025 Nov 4;15(1):38609
Ly96-mediated activation of TGF-β1/Smad2/3 signaling in hepatocellular carcinoma and its potential for nanoparticle-based therapy.
Zhang Y, Zheng S, Su X, Luo W, Tang H, Xiong S, Tan M, Luo B
Acta biochimica et biophysica Sinica 2025 Nov 3;58(4):865-81
Acta biochimica et biophysica Sinica 2025 Nov 3;58(4):865-81
Dapagliflozin ameliorates high glucose-induced peritoneal fibrosis through downregulation of ENKUR/PI3K/AKT signaling pathway.
Liu J, Xu X, Zhang L, Jiang T, Zhao Z, Xiao J
Scientific reports 2025 Nov 3;15(1):38334
Scientific reports 2025 Nov 3;15(1):38334
Aucubin inhibits the activity of lung cancer stem-like cells by targeting degradation of β-catenin.
Li Q, Xie H, Li L, Yan W, Liu G
The Journal of pharmacy and pharmacology 2025 Nov 28;77(12):1777-1786
The Journal of pharmacy and pharmacology 2025 Nov 28;77(12):1777-1786
RTA-408 Enhances Radiosensitivity and Inhibited Tumor Progression via JNK Pathway in Glioblastoma.
Tsai HP, Qin H, Chong YB, Chen IH, Kuo SH, Tseng TT, Lieu AS
The Kaohsiung journal of medical sciences 2025 Nov 28;:e70142
The Kaohsiung journal of medical sciences 2025 Nov 28;:e70142
HCAR2 inhibits prostate cancer invasion and metastasis by regulating cAMP signaling pathway.
Li Y, Chen H, Huang R
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2025 Nov 28;:10815589251406272
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2025 Nov 28;:10815589251406272
hsa_circ_0135681 functions as a novel tumor-suppressive circular RNA regulating Glycolysis and EMT to attenuate cisplatin resistance in non-small cell lung cancer.
Song X, Li H, Zhu Y, Wei G, Li X, Wei H, Zhao H, Zhu C, Chen F
Discover oncology 2025 Nov 27;17(1):3
Discover oncology 2025 Nov 27;17(1):3
GLMP promotes EGFR-TKI resistance by activating autophagy and RhoA pathway in non-small cell lung cancer.
Liang X, Xu J, Shu S, Lv W, Yin D, Miao S, Lu X, Zhang C, Liu X, Dai J, Li J, Wu W, Zhang E, Guo R
NPJ precision oncology 2025 Nov 26;9(1):391
NPJ precision oncology 2025 Nov 26;9(1):391
Protein kinase D2-mediated maintenance complex component 2 phosphorylation promotes bladder cancer progression.
Tian H, Song J, Cong J, Zhang Z, Di Y, Yan B, Nan X
Journal of translational medicine 2025 Nov 26;23(1):1357
Journal of translational medicine 2025 Nov 26;23(1):1357
CAFs-derived SPI1 in tumor fibroblasts promotes malignant behaviors of liver cancer cells and immune escape by regulating HRAS and PD-L1 transcription.
Miao K, Zhou J, Chen J
Hereditas 2025 Nov 26;162(1):233
Hereditas 2025 Nov 26;162(1):233
Sec14L6 is a phosphoinositide transporter that regulates phosphoinositide homeostasis and biogenesis of lipid droplets.
Zhou T, Xiong J, Hu X, Du Y, Shi A, Chang W, Qin J, Deng L, Ji WK
Nature communications 2025 Nov 26;16(1):10518
Nature communications 2025 Nov 26;16(1):10518
Jianpi Huayu decoction exerts antitumor effects in pancreatic cancer via SCD1-mediated lipid metabolism remodeling/ferroptosis axis.
Chen X, Ren Y, Yao R, Liu S, Fang C, Luo R, Shi H, Zhu X, Lai Y, Zhao X, Zhong C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157389
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157389
Zhilining formula alleviates ulcerative colitis by restricting STAT3 activation and subsequent Th17 cell differentiation.
Yang H, Gao J, Yang Y, Sun J, Zeng H, Zhang Y, Feng S, Ma X, Zhu Q, Wang X, Zhang Y, Lv Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157379
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157379
Anti-tumor effects of Cinnamomum camphora essential oil in breast cancer via NOX4 modulation by (+)-2-bornanone.
Zheng R, He Y, Wang Y, Chen Y, Yang L, Wang R, Wu S, Xie H, Xie S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157327
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157327
Ferulic acid ameliorates TLR4-mediated macrophage activation by irreversibly binding to peroxiredoxin 1 to inhibit its dimerization and secretion.
Gao J, Yan J, Zu X, Xu Y, Wang S, Li Y, Zhao Z, Hou Y, Bai G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157254
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157254
Silencing Clusterin Could Attenuate the Cell Properties of HCV Core Protein-Expressing HCC Cell Line.
Han F, Cui C, Cui J, Zang S, Zhao Z, Ren W, Zhang Q, Liu L, Dong S, Fu N, Nan Y
Digestive diseases and sciences 2025 Nov 25;
Digestive diseases and sciences 2025 Nov 25;
Dynamic remodelling of epithelial plasticity in colorectal cancer from single-cell and spatially resolved perspectives.
Xu C, Pan Y, Zhang S, Lin M, Liu H, Yu Z
Journal of translational medicine 2025 Nov 24;23(1):1341
Journal of translational medicine 2025 Nov 24;23(1):1341
Keratin 80 serves as a potential biomarker in metastatic breast cancer.
Sun F, Wang D, Chen M, Lin X
Discover oncology 2025 Nov 24;16(1):2158
Discover oncology 2025 Nov 24;16(1):2158
RBMX2 links Mycobacterium bovis infection to epithelial-mesenchymal transition and lung cancer progression.
Wang C, Peng Y, Yang H, Jiang Y, Khalid AK, Zhang K, Xie S, Bermudez L, Yang Y, Zhang L, Chen H, Guo A, Chen Y
eLife 2025 Nov 24;14
eLife 2025 Nov 24;14
BNC2 as a novel driver of pancreatic cancer progression through transcriptional regulation of COL3A1 and epithelial-to-mesenchymal transition.
Li X, Yu T, Yu Z, Zou X, He J, Wang D, Shen X, Liu S, Liu B
Medical oncology (Northwood, London, England) 2025 Nov 21;43(1):11
Medical oncology (Northwood, London, England) 2025 Nov 21;43(1):11
ZIC5, a survival biomarker, facilitates tumor progression and stemness in colon cancer via the activation of the Wnt signaling pathway.
Li X, Zhao C, Mu M, Yuan H, Chen G, Chen S, Huo X, Sun X, Yu J
Scientific reports 2025 Nov 20;15(1):40943
Scientific reports 2025 Nov 20;15(1):40943
HMGA1 drives EMT in obliterative bronchiolitis through epigenetic regulation of chromatin accessibility in pulmonary epithelial cells.
Xia T, Hou Z, Wang S, Sun J, Yang H, Miao P, Liu C, Zheng W, Wei L
Clinical epigenetics 2025 Nov 18;17(1):192
Clinical epigenetics 2025 Nov 18;17(1):192
Novel bakuchiol derivatives inhibit the migration and invasion of non-small cell lung cancer by suppressing epithelial-to-mesenchymal transition.
Xu MF, Zhong K, Zhu J, Chen J, Liu F, Ding F, Wu CZ, Zhao L
RSC advances 2025 Nov 18;15(53):45233-45244
RSC advances 2025 Nov 18;15(53):45233-45244
Influenza a(H1N1) virus infection impairs syncytiotrophoblast functions by promoting ferroptosis through the TNF-α/ISG15/EGR1 axis.
Zhao Y, Wang Y, Huang K, Wang F, Wang Y
Virology journal 2025 Nov 17;22(1):379
Virology journal 2025 Nov 17;22(1):379
Ozone aging amplifies the tumor-promoting effects associated with low-dose graphene oxide exposure in bladder tumors via the integrin αV signaling pathway.
Zhu J, Yi B, Ma J, Zhang S, Zhou Z, Qi Y, Qi S
Ecotoxicology and environmental safety 2025 Nov 15;307:119458
Ecotoxicology and environmental safety 2025 Nov 15;307:119458
Antimony exposure induces bladder cancer metastasis via activation of the SUMOylation-dependent TGF-β/Smad2/3 axis.
Yi B, Zhao Z, Gao X, Zhao D, Liu X, Zhang W, Zhang Z, Zhang C
Environmental research 2025 Nov 15;285(Pt 4):122589
Environmental research 2025 Nov 15;285(Pt 4):122589
Therapeutic potential of the LUCAT1/miR- 2278/STAT5A axis in pulmonary fibrosis.
Huang J, Zhang W
BMC pulmonary medicine 2025 Nov 14;25(1):528
BMC pulmonary medicine 2025 Nov 14;25(1):528
Curcumenol exerts anti-pulmonary fibrosis effects through modulation of the immune signature target SPP1: based on comprehensive bioinformatics and experiments validation.
Li C, Wen R, Xiong Y, Tan QW, Zhai XY, Xiong Y, Dai LS
International immunopharmacology 2025 Nov 14;165:115469
International immunopharmacology 2025 Nov 14;165:115469
MiR-5095 inhibits proliferation, migration, and invasion of gastric cancer cells by targeting CEACAM5.
Lin W, Cai R, Fan W, Zhang X, He F, Miao Y, Qian H, Zhao W, Zhu Y
Scientific reports 2025 Nov 14;15(1):39950
Scientific reports 2025 Nov 14;15(1):39950
S100 Calcium-Binding Protein P and Cathepsin E as Key Mediators in Pancreatic Cancer Tumorigenesis.
Meng Y, Deng Q, Zhang Y, Wei F, Wu J, Yan H
Biomedicines 2025 Nov 14;13(11)
Biomedicines 2025 Nov 14;13(11)
AARS1 promotes endometriosis progression by promoting the lactylation of Snail1†.
Liu L, Du S, Liu J, Wang M, Ge X, Yue C, Lu C, Yu Z
Biology of reproduction 2025 Nov 14;113(5):1209-1218
Biology of reproduction 2025 Nov 14;113(5):1209-1218
Ginsenoside Rh2 as a novel PIN1 inhibitor disrupting the cancer stem cell-like phenotype in non-small cell lung cancer.
Liu X, Mao Z, Yang J, Zhu Q, Dong X, Huang G, Shen X, Zhang L, Yang H
Journal of translational medicine 2025 Nov 10;23(1):1256
Journal of translational medicine 2025 Nov 10;23(1):1256
A PCD-related prognostic signature and the oncogenic role of TRIM8 in osteosarcoma progression.
Zhang L, Ou X, Wang Q, Shi S
Journal of translational medicine 2025 Nov 10;23(1):1249
Journal of translational medicine 2025 Nov 10;23(1):1249
Optimized inner ear organoids for efficient hair cell generation and ototoxicity response modeling.
Qin X, Fu L, Li C, Tan X, Yin X
Science China. Life sciences 2025 May;68(5):1369-1383
Science China. Life sciences 2025 May;68(5):1369-1383
Overexpression of PLK1 Molecule Following Incomplete Thermal Ablation Promotes the Proliferation and Invasion of Residual Hepatocellular Carcinoma.
Kang T, Chen J, Wan W, Pang J, Wen R, Bai X, Li L, Pan Y, He Y, Yang H
Molecular biotechnology 2025 May;67(5):2046-2059
Molecular biotechnology 2025 May;67(5):2046-2059
The efficacy and underlying mechanisms of berberine in the treatment of recurrent Clostridioides difficile infection.
Wang L, Xu T, Wu S, Zhao C, Huang H
International journal of antimicrobial agents 2025 May;65(5):107468
International journal of antimicrobial agents 2025 May;65(5):107468
Single-cell and spatial RNA sequencing identify divergent microenvironments and progression signatures in early- versus late-onset prostate cancer.
Cheng Y, Liu B, Xin J, Wu X, Li W, Shang J, Wu J, Zhang Z, Xu B, Du M, Cheng G, Wang M
Nature aging 2025 May;5(5):909-928
Nature aging 2025 May;5(5):909-928
KMT2A facilitates the epithelial-to-mesenchymal transition and the progression of ovarian cancer.
Zhu Y, Jiang S, Tang R, Chen H, Jia G, Zhou X, Miao J
Molecular and cellular biochemistry 2025 May;480(5):3001-3017
Molecular and cellular biochemistry 2025 May;480(5):3001-3017
PRSS23-eIF4E-c-Myc axis promotes gastric tumorigenesis and progression.
Zhou X, Guo Z, Pan Y, Yang S, Yan R
Oncogene 2025 May;44(17):1167-1181
Oncogene 2025 May;44(17):1167-1181
Protective effects of jiawei yupingfeng polysaccharides on cyclophosphamide-induced intestinal injury in mice.
Wu R, Zhao N, Li H, Zhang W, Hua Y, Ji P, Wei Y
International journal of biological macromolecules 2025 May;310(Pt 3):143405
International journal of biological macromolecules 2025 May;310(Pt 3):143405
An exploration on the involvement of the methyltransferase like 3-m(6)A‑zinc finger MYM-type containing 1 axis in the progression of liver hepatocellular carcinoma.
Chen W, Meng Y, Zhan S, Xiong F, Wang L, Yao J
International journal of biological macromolecules 2025 May;309(Pt 4):142820
International journal of biological macromolecules 2025 May;309(Pt 4):142820
METTL3-mediated m6A modification of PAK6 drives cervical cancer progression through activating MAPK14.
Zhu ZM, Huo FC, Shi C, Li MT, Zhou Y, Zhang LS, Pei DS
International journal of biological macromolecules 2025 May;309(Pt 2):142880
International journal of biological macromolecules 2025 May;309(Pt 2):142880
HKDC1 promotes colorectal cancer progression by regulating RCOR1 expression to activate the Wnt/β-catenin pathway, enhancing proliferation, migration, and epithelial-mesenchymal transition.
Huang S, Pang Q, Zhang Y, Cao J
The Journal of biological chemistry 2025 May;301(5):108478
The Journal of biological chemistry 2025 May;301(5):108478
A novel 5-differentially expressed gene (DEG) signature predicting the prognosis in patients with metastatic liver malignancies and the prognostic and therapeutic potential of SPP1.
Liu J, Yu Z, Liu Q, Dou C, Cao P, Xie X
International journal of clinical oncology 2025 May;30(5):956-973
International journal of clinical oncology 2025 May;30(5):956-973
Kv1.3 expression on CD4 (+) T cells promotes interleukin-17A-associated airway inflammation and airway remodeling in asthma.
Sun B, Lin J
Translational research : the journal of laboratory and clinical medicine 2025 May;279:40-54
Translational research : the journal of laboratory and clinical medicine 2025 May;279:40-54
PTPRG-AS1 regulates the KITLG/KIT pathway through the ceRNA axis to promote the malignant progression of gastric cancer and the intervention effect of Compound Kushen injection on it.
Wu C, Gao Y, Jin Z, Huang Z, Wang H, Lu S, Guo S, Zhang F, Zhang J, Huang J, Tao X, Liu X, Zhang X, You L, Li Q, Wu J
Pharmacological research 2025 May;215:107743
Pharmacological research 2025 May;215:107743
CHPF2 as a novel biomarker and ponicidin as a potential therapeutic agent in hepatocellular carcinoma.
Liang Z, Ye Y, Deng Z, Lan H, Liu C, Xu Y, Fan M, Liu Z, Wu P, An L, Wang C
Pharmacological research 2025 May;215:107698
Pharmacological research 2025 May;215:107698
Circular RNA ATP9A Stimulates Non-small Cell Lung Cancer Progression via MicroRNA-582-3p/Ribosomal Protein Large P0 Axis and Activating Phosphatidylinositol 3-Kinase/Protein Kinase B Signaling Pathway.
Wang D, Huang W, Li G
Applied biochemistry and biotechnology 2025 May;197(5):3166-3183
Applied biochemistry and biotechnology 2025 May;197(5):3166-3183
EFNA2 Mediates Stiffness-Regulated Hypopharyngeal Cancer Progression.
Hu S, Liu Y, Cheng M, Xu M, Liu H, Shan Y, Ni H, Xia T, Zhang Q, Zhang Z, You B
Clinical and experimental otorhinolaryngology 2025 May;18(2):188-199
Clinical and experimental otorhinolaryngology 2025 May;18(2):188-199
Jiawei Danxuan Koukang and its key component Quercetin intervened in OSF carcinogenesis by inhibiting the AR/eIF5A2 signaling pathway-mediated EMT.
Dai Y, Wang C, Xiao Y, Tan Y, Ye Y, Liu Y, Zeng Q, Tan J
Archives of oral biology 2025 May;173:106194
Archives of oral biology 2025 May;173:106194
EGFR-mediated crosstalk between vascular endothelial cells and hepatocytes promotes Piezo1-dependent liver regeneration.
Hu Y, Du G, Li C, Wang R, Liu J, Wang Y, Dong J
Genes & diseases 2025 May;12(3):101321
Genes & diseases 2025 May;12(3):101321
From Invaginating Site to Deep Lesion: Spatial Transcriptomics Unravels Ectopic Endometrial Penetration Features in Adenomyosis.
Li B, Qi J, Cao Y, Long Y, Wei Z, Wang WS, Hu S, Wang Y, Zhu Q, Hu X, Sun Z, Zhu J, Ye T, Yao Y, Meng Y, Bian X, Dong X, Guan H, Huang Y, Sun Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(20):e2411752
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(20):e2411752
Novel Phenoxyacetic Acid (4-Aminophenoacetic Acid) Shikonin Ester Kills KRAS Mutant Colon Cancer Cells via Targeting the Akt Allosteric Site.
Ma Y, Sun Y, Tu Q, Lin F, Mei F, Chen Q, Fu T, Yang L, Lai X, Yang M, Yin T, Lu G, Qi J, Lin H, Wen Z, Yang Y, Han H
Chemical biology & drug design 2025 May;105(5):e70125
Chemical biology & drug design 2025 May;105(5):e70125
Artesunate Enhances Sensitivity of Renal Cancer Cells to Sunitnib by Mediating Tripartite Motif Containing 24-Induced Ubiquitination of Paired Box 6.
Cui Z, Wen J, Yang G, Wei L, Chen H, Zhao Q, Yang S, Yu J, Huang Y, Tan S, Mo Q, Qin M, Cheng J
Chemical biology & drug design 2025 May;105(5):e70116
Chemical biology & drug design 2025 May;105(5):e70116
Metabolic-associated fatty liver disease (MAFLD) promotes the progression of hepatocellular carcinoma by enhancing KIF20A expression.
Hu X, Chen Y, Ying H, He C, Ren Y, Tian Y, Tan Y
International immunopharmacology 2025 May 8;154:114589
International immunopharmacology 2025 May 8;154:114589
Integrated Analysis of Disulfidptosis-Related Genes Identifies CD2AP as a Potential Therapeutic Target for Hepatocellular Carcinoma.
Shang N, Wang J, Liu Z, Wang Y, Zhang D, Liu H, Zhang Y, Dai G, Guan X
International journal of molecular sciences 2025 May 7;26(9)
International journal of molecular sciences 2025 May 7;26(9)
The high expression of Long noncoding RNA TEX41 promotes the proliferation, migration, and invasion of hepatocellular carcinoma.
Li Z, Xu H, Chen H, Chen L, Zang H, Qian Y
Translational cancer research 2025 May 30;14(5):3175-3185
Translational cancer research 2025 May 30;14(5):3175-3185
The lncRNA MIR22HG suppresses prostate cancer cell proliferation, migration, and epithelial-mesenchymal transition via the miR-4428/PCDH9 axis.
Li A, Sun W, Shao S, Qiu X, Hu J, Cui F
Translational cancer research 2025 May 30;14(5):3133-3148
Translational cancer research 2025 May 30;14(5):3133-3148
Enhanced mitochondrial biogenesis facilitates the development of cutaneous squamous cell carcinoma.
Wang Z, He K, Liu M, Lv W, Cheng B, Zhang G, Wang X, Zeng M, Jiao L, Han S, Zheng Y, Feng Z
Cancer letters 2025 May 28;618:217623
Cancer letters 2025 May 28;618:217623
Metabolite-dependent m(6)A methylation driven by mechanotransduction-metabolism-epitranscriptomics axis promotes bone development and regeneration.
Li Z, Guo Z, Yang Z, Yang B, Hu Y, Xie X, Zong Z, Chen Z, Zhang K, Zhao P, Li G, Yang X, Bian L
Cell reports 2025 May 27;44(5):115611
Cell reports 2025 May 27;44(5):115611
SPINT1 Expressed in Epithelial Cells of Choroid Plexus in Human and Mouse Brains.
Murakami R, Chiba Y, Takebayashi G, Wakamatsu K, Miyai Y, Matsumoto K, Uemura N, Yanase K, Ogino Y, Ueno M
International journal of molecular sciences 2025 May 27;26(11)
International journal of molecular sciences 2025 May 27;26(11)
Enhanced anti-cancer effect of AMTB hydrochloride via chitosan nanoparticles in pancreatic cancer.
Liu J, Gong Y, Zeng X, He M, He B, Gao W, Gao Y
BMC cancer 2025 May 26;25(1):944
BMC cancer 2025 May 26;25(1):944
GP73-dependent regulation of exosome biogenesis promotes colorectal cancer liver metastasis.
Huang L, Wei M, Li H, Yu M, Wan L, Zhao R, Gao Q, Sun L, Hou X, Mo Y, Huang Q, Zhen L, Yang X, Li J, Wang N, Zhang C, Jin H, Zhou L, Xu Y, Lin H, Zhang X, Li B, Han Y, Yuan J, Zhang R, Wu F, Zhong H, Wei C
Molecular cancer 2025 May 26;24(1):151
Molecular cancer 2025 May 26;24(1):151
Cinobufagin inhibits hepatocellular carcinoma EMT-like stemness via VEGF/VEGFR2 autocrine signaling.
Ye M, Chen S, Lu C, Wu Y, Tian J, Han A, Zhu J, Li B, Li Q
Discover oncology 2025 May 26;16(1):930
Discover oncology 2025 May 26;16(1):930
The Therapeutic Potential of Bombyx Batryticatus for Chronic Atrophic Gastritis Precancerous Lesions via the PI3K/AKT/mTOR Pathway Based on Network Pharmacology of Blood-Entering Components.
Wang X, Chang M, Feng K, Wang Q, Li B, Gao W
Pharmaceuticals (Basel, Switzerland) 2025 May 25;18(6)
Pharmaceuticals (Basel, Switzerland) 2025 May 25;18(6)
MiR-493-5p functions as a tumour suppressor in head and neck squamous cell carcinoma progression by targeting HIF-1α.
Liu J, Tian R, Chen X, Song Q, Sun C, Li D, Fang Y, Lv S, Li Y, Song X
Discover oncology 2025 May 24;16(1):899
Discover oncology 2025 May 24;16(1):899
miRNA-1229-5p promotes migration and invasion and suppresses apoptosis of endometrial cells via the STMN1/p38 MAPK axis in endometriosis.
Liu L, Wang L, Hao N, Du N, Li Y, Kang S
Gene 2025 May 20;950:149385
Gene 2025 May 20;950:149385
GALR1 and PENK serve as potential biomarkers in invasive non-functional pituitary neuroendocrine tumours.
Wu Z, Rao C, Xie Y, Ye Z, Zhang Y, Ma Z, Su Z, Ye Z
Gene 2025 May 20;950:149374
Gene 2025 May 20;950:149374
A dual-targeting bio-liposomes nanodrug repair endothelial cell dysfunction and restore macrophage cholesterol flow homeostasis to treat early atherosclerosis.
Zhang Q, Ma S, Kang X, Liu Y, Ma F, Yu F, Luo X, Li G, Hao Y, Zhang H, Liu B, Jiang Y
Journal of nanobiotechnology 2025 May 20;23(1):365
Journal of nanobiotechnology 2025 May 20;23(1):365
TMBIM1 promotes epithelial mesenchymal transition by accelerating autophagic degradation of E-cadherin in glioblastoma.
Gao L, Liu J, Li Y, Yang J, Cai J, Wang L, Ye Z, Tong S, Deng G, Chen Q, Cai Q
Scientific reports 2025 May 20;15(1):17488
Scientific reports 2025 May 20;15(1):17488
Fibrogenesis-driven tumor progression in clear cell renal cell carcinoma: prognostic, therapeutic implications and the dual role of neuropilin-1.
Wang K, Shen X, Wu J, Bi Q, Gao Z, Sun Z, Wang W
Cancer cell international 2025 May 16;25(1):179
Cancer cell international 2025 May 16;25(1):179
Piezo1 regulates actin cytoskeleton remodeling to drive EMT in cervical cancer through the RhoA/ROCK1/PIP2 signaling pathway.
Deng J, Li Y, Zhang L, Liao W, Liu T, Shen F
Discover oncology 2025 May 16;16(1):787
Discover oncology 2025 May 16;16(1):787
Bufei Yishen formula alleviates airway epithelial cell senescence in COPD by activating AMPK-Sirt1-FoxO3a pathway and promoting autophagy.
Cheng M, Yang M, Tian Y, Liu X, Li J, Zhao P
Scientific reports 2025 May 13;15(1):16584
Scientific reports 2025 May 13;15(1):16584
CPT1A/HIF-1α positive feedback loop induced fatty acid oxidation metabolic pathway contributes to the L-ascorbic acid-driven angiogenesis in breast cancer.
Ma X, Zhang B, Yin X, Yang S, Lin Z, Yang Y, Zhou X
Breast cancer research : BCR 2025 May 12;27(1):74
Breast cancer research : BCR 2025 May 12;27(1):74
A novel scheme for non-invasive drug delivery with a magnetically controlled drug delivering capsule endoscope.
Wang W, Zhang K, Ming F, Chen B, Zhang H, Wang Z, Jiang X, Zhang H, Shang G, Bao Y, Peng H, Liu S, Ling X, Li W, Zhu H, Zhang Y, Cai S, Ding Z, Lin R
Journal of controlled release : official journal of the Controlled Release Society 2025 May 10;381:113591
Journal of controlled release : official journal of the Controlled Release Society 2025 May 10;381:113591
A novel lncRNA ABCE1-5 regulates pulmonary fibrosis by targeting KRT14.
Gao S, Wei Y, Li C, Xie B, Zhang X, Cui Y, Dai H
American journal of physiology. Cell physiology 2025 May 1;328(5):C1487-C1500
American journal of physiology. Cell physiology 2025 May 1;328(5):C1487-C1500
Knowledge-guided multi-level network modeling with experimental characterization identifies PRKCA as a novel biomarker and tumor suppressor triggering ferroptosis in prostate cancer.
Lin Y, Jia Z, Wu J, Yang H, Chen X, Wang H, Wei X, Yan W, Qi X, Huang Y
Briefings in bioinformatics 2025 May 1;26(3)
Briefings in bioinformatics 2025 May 1;26(3)
Depletion of Acetyl-CoA Carboxylase 1 Facilitates Epithelial-Mesenchymal Transition in Prostate Cancer Cells by Activating the MAPK/ERK Pathway.
Lai J, Liu S, Chen Y, Chen J, Li J, Liang Z, Mei X, Feng Y, Han Z, Jiang F, Yang S, Wu Y, Tan H, Liu J, He H, Zhong W
MedComm 2025 Mar;6(3):e70126
MedComm 2025 Mar;6(3):e70126
Targeting ADAR1 with a small molecule for the treatment of prostate cancer.
Wang X, Li J, Zhu Y, Shen H, Ding J, Zeng T, Min W, Liang SQ, Huang L, Shi Z, Shen H, Huang F, Yuan K, Kuang W, Ji M, Sun C, Hou Y, Wang L, Chen W, Jiang Y, Hao H, Xiao Y, Yang P
Nature cancer 2025 Mar;6(3):474-492
Nature cancer 2025 Mar;6(3):474-492
Research on LCN2 interference to enhance the sensitivity of drug-resistant strains to gemcitabine.
Lei J, Li X, Wang X, Xiao Y, Chi Y, Sun Q, Zhang H
Xenobiotica; the fate of foreign compounds in biological systems 2025 Mar;55(3):230-238
Xenobiotica; the fate of foreign compounds in biological systems 2025 Mar;55(3):230-238
Cellular heterogeneity and communication networks in gastric cancer: Single-cell analysis reveals β-hydroxybutyrylation-associated genes and immune infiltration characteristics.
Hu Y, Xu J, Lv J, Qin Y, Lu Y, Cen F, Yang H, Chen K, Xia S
Translational oncology 2025 Mar;53:102270
Translational oncology 2025 Mar;53:102270
Breast cancer stem cell-derived exosomal lnc-PDGFD induces fibroblast-niche formation and promotes lung metastasis.
Tang T, Yang T, Xue H, Liu X, Yu J, Liang C, Li D, Xiang C, Zheng J, Wei L, Ma B
Oncogene 2025 Mar;44(9):601-617
Oncogene 2025 Mar;44(9):601-617
Bergapten Ameliorates Renal Fibrosis by Inhibiting Ferroptosis.
Li L, Cai W, Zhang H, Tang J, Yang Y, Huang Y, Xi Q, Zhang R
Phytotherapy research : PTR 2025 Mar;39(3):1355-1371
Phytotherapy research : PTR 2025 Mar;39(3):1355-1371
UBE2Q1 as a novel cancer biomarker for lung adenocarcinoma.
Jiang W, Wang Y, Zou J, Li L, Xu C
The American journal of the medical sciences 2025 Mar;369(3):359-365
The American journal of the medical sciences 2025 Mar;369(3):359-365
The role of Collagen Tissue Scaffolds in 3D Endometrial-like Culture Systems: Important Contributions to Cell Invasion and Cell Topography.
Kendirci-Katirci R, Sendemir A, Hameş EE, Vatansever HS
Reproductive sciences (Thousand Oaks, Calif.) 2025 Mar;32(3):895-906
Reproductive sciences (Thousand Oaks, Calif.) 2025 Mar;32(3):895-906
FXYD5 regulates gastric cancer cell metastasis and drug resistance by EMT modulation.
Mao Y, Hu Y, Meng H, Qin J, An Q, Zhang C, Guo C, Zhao Y, Tan D, Ge X, Shi C
Cancer gene therapy 2025 Mar;32(3):318-326
Cancer gene therapy 2025 Mar;32(3):318-326
USP1 promotes pancreatic cancer progression and autophagy by deubiquitinating ATG14.
Li L, Fan Z, Liu M, Dong H, Li J, Li Y, Song Z, Liu Y, Zhang Z, Gu X, Zhang T
The Journal of biological chemistry 2025 Mar;301(3):108190
The Journal of biological chemistry 2025 Mar;301(3):108190
The MCM6-c-Myc positive feedback loop mediates bladder cancer progression and cisplatin resistance.
Wang J, Li X, Zhao L, Fan X, Cao J, Wang S, Li K, Wang H, Zhang Y, Wang H, Xu C, Ding L, Che T, Chen S, Yang L
International journal of biological macromolecules 2025 Mar;296:139777
International journal of biological macromolecules 2025 Mar;296:139777
Chemerin's Role in Endometrial Dysfunction: Insights From Transcriptomic Analysis.
Yu M, Wang Y, Cai J, Dong X, Wang H, Sun Z, Xiao T, Chen J, Li M, Shan C, Dong Y, Zhang JV
Journal of cellular and molecular medicine 2025 Mar;29(6):e70417
Journal of cellular and molecular medicine 2025 Mar;29(6):e70417
DDR1 Targeting HOXA6 Facilitates Bladder Cancer Progression via Inhibiting Ferroptosis.
Xie X, He H, Zhang N, Wang X, Rui W, Xu D, Zhu Y, Tian M, He W
Journal of cellular and molecular medicine 2025 Mar;29(6):e70410
Journal of cellular and molecular medicine 2025 Mar;29(6):e70410
Ubiquitin-specific peptidase 10 promotes renal interstitial fibrosis progression through deubiquitinating and stabilizing P53 protein.
Liu S, Yang Y, Li Q, Yu L, Zong Z, Zang R, Ji W, Sun S
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167660
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167660
High MICAL-L2 promotes cancer progression and drug resistance in renal clear cell carcinoma cells through stabilization of ACTN4 following vimentin expression.
Zhao W, Qi C, Mao Y, Ye F, Xia T, Zhao M, Min P, Zhang Y, Du J
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167628
Biochimica et biophysica acta. Molecular basis of disease 2025 Mar;1871(3):167628
β-eudesmol inhibits cell growth and enhances cell chemosensitivity of NPC through targeting FGF1/FGFR signaling.
Xie T, Shu Y, Huang W, Ren A, Lin J, Tan Y, Zhao S, Bu J
Oral oncology 2025 Mar;162:107168
Oral oncology 2025 Mar;162:107168
circTUBD1-hnRNPK Regulates the Proliferation and Migration of LSCC by Targeting CCAR1.
Xu Y, Qiu S, Shen Z, Chen J
Cancer medicine 2025 Mar;14(6):e70834
Cancer medicine 2025 Mar;14(6):e70834
SSBP1 positively regulates RRM2, affecting epithelial mesenchymal transition and cell cycle arrest in human lung adenocarcinoma cells.
Yang X, Ma B, Liu Y, Zhou J, Guo J, Peng Y, Bai Y, Wu J, Hu D
Cellular signalling 2025 Mar;127:111552
Cellular signalling 2025 Mar;127:111552
Excessive MYC Orchestrates Macrophages induced Chromatin Remodeling to Sustain Micropapillary-Patterned Malignancy in Lung Adenocarcinoma.
Song X, Pan Z, Zhang Y, Yang W, Zhang T, Wang H, Chen Y, Yu X, Ding H, Li R, Ge P, Xu L, Dong G, Jiang F
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(12):e2403851
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(12):e2403851
Intestine-Decipher Engineered Capsules Protect Against Sepsis-induced Intestinal Injury via Broad-spectrum Anti-inflammation and Parthanatos Inhibition.
Yan Y, Li B, Gao Q, Wu M, Ma H, Bai J, Ma C, Xie X, Gong Y, Xu L, Li X, Wang W, Wu Y, Wang J, Wang H, Feng Y, Zhang Y, Li P, Shi H, Ma F, Jia Y, Duan H, Fu X, Wang W, Zhan L, Du X, Zhou H, Liao Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(10):e2412799
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(10):e2412799
MLLT3 Regulates Melanoma Stemness and Progression by Inhibiting HMGB1 Nuclear Entry and MAGEA1 M(5)C Modification.
Li Y, Liu H, Li J, Fu C, Jiang B, Chen B, Zou Y, Yu B, Song B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(10):e2408529
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(10):e2408529
Silencing long non-coding RNA linc00689 suppresses the growth and invasion of osteosarcoma cells by targeting miR-129-5p/NUSAP1.
Zhang L, Song J, Xu X, Sun D, Huang H, Chen Y, Zhang T
International journal of experimental pathology 2025 Mar;106(2):e12524
International journal of experimental pathology 2025 Mar;106(2):e12524
Melatonin affects trophoblast epithelial-to-mesenchymal transition and oxidative damage resistance by modulating GDF15 expression to promote embryo implantation.
Yang G, Yao G, Wang H, Jiang R, Fang J, Hu J, Kong Y, Jin H, Song W, Wu Z, Huang X, Sun Y
Communications biology 2025 Mar 8;8(1):396
Communications biology 2025 Mar 8;8(1):396
HNRNPC promotes progression of non-small cell lung cancer by maintaining TFAP2A mRNA stability.
Liao M, Li C, Yang R, Li J, Wu K, Zhang J, Zhu Q, Shi Y, Zhang X
Cancer cell international 2025 Mar 8;25(1):85
Cancer cell international 2025 Mar 8;25(1):85
Parvimonas micra promotes oral squamous cell carcinoma metastasis through TmpC-CKAP4 axis.
Qi H, Gao H, Li M, Sun T, Gu X, Wei L, Zhi M, Li Z, Fu D, Liu Y, Wei Z, Dou Y, Feng Q
Nature communications 2025 Mar 7;16(1):2305
Nature communications 2025 Mar 7;16(1):2305
Semaglutide, a glucagon-like peptide-1 receptor agonist, inhibits oral squamous cell carcinoma growth through P38 MAPK signaling pathway.
Wang C, Wu Z, Zhou J, Cheng B, Huang Y
Journal of cancer research and clinical oncology 2025 Mar 7;151(3):103
Journal of cancer research and clinical oncology 2025 Mar 7;151(3):103
cGAS-STING mediates neutrophil extracellular traps-induced EMT in myositis-associated interstitial lung disease: STING as a potential therapeutic target.
Feng Y, Su Q, Zhu J, Cui X, Guo J, Yang J, Zhang S
International immunopharmacology 2025 Mar 6;149:114144
International immunopharmacology 2025 Mar 6;149:114144
Inhibition of NLRP3 alleviates calcium oxalate crystal-induced renal fibrosis and crystal adhesion.
Xu Y, Li G, Liu W, Ge D, Hao Z, Wang W
Urolithiasis 2025 Mar 4;53(1):44
Urolithiasis 2025 Mar 4;53(1):44
c-Jun promotes neuroblastoma cell differentiation by inhibiting APC formation via CDC16 and reduces neuroblastoma malignancy.
Wang Y, Huang J, Song Z, Zhang S, Guo H, Leng Q, Fang N, Ji S, Yang J
Biology direct 2025 Mar 27;20(1):37
Biology direct 2025 Mar 27;20(1):37
miR-378d suppresses gastric cancer metastasis by targeting METTL4 to inhibit epithelial-mesenchymal transition.
Xing D, Bao J, He J, Gao H, Xue W, Chen J, Li J
Journal of molecular histology 2025 Mar 22;56(2):116
Journal of molecular histology 2025 Mar 22;56(2):116
Protocol for generating brain metastatic tumor cells through repeated intracardiac injections in mice.
Wang L, Chen X, Dong C, Yin S, Liang L, Zhou A
STAR protocols 2025 Mar 21;6(1):103531
STAR protocols 2025 Mar 21;6(1):103531
Single-molecule m(6)A detection empowered by endogenous labeling unveils complexities across RNA isoforms.
Guo W, Ren Z, Huang X, Liu J, Shao J, Ma X, Wei C, Cun Y, He J, Zhang J, Wu Z, Guo Y, Zhang Z, Feng Z, He J, Wang J
Molecular cell 2025 Mar 20;85(6):1233-1246.e7
Molecular cell 2025 Mar 20;85(6):1233-1246.e7
Rare and common genetic variants underlying the risk of Hirschsprung's disease.
Xiao J, Feng C, Zhu T, Zhang X, Chen X, Li Z, You J, Wang Q, Zhuansun D, Meng X, Wang J, Xiang L, Yu X, Zhou B, Tang W, Tou J, Wang Y, Yang H, Yu L, Liu Y, Jiang X, Ren H, Yu M, Chen Q, Yin Q, Liu X, Xu Z, Wu D, Yu D, Wu X, Yang J, Xiong B, Chen F, Hao X, Feng J
Human molecular genetics 2025 Mar 20;34(7):586-598
Human molecular genetics 2025 Mar 20;34(7):586-598
Isoliquiritigenin attenuates tumor progression and PD-L1 expression by inhibiting the phosphorylation of STAT3 in melanoma.
Zeng H, Guo A, Liu Z, Xiang S, Zheng F
Medical oncology (Northwood, London, England) 2025 Mar 19;42(4):118
Medical oncology (Northwood, London, England) 2025 Mar 19;42(4):118
TMEM176B inhibits ovarian cancer progression by regulating EMT via the Wnt/β-catenin signaling pathway.
Yan L, Song Z, Yi L, Tian C, Zhang R, Qin X, Wang X, Ren S, Ma X, Wang X, Zhao X, Wang F, Wei J, Jia X, Gu M, Yuan F, Jia D
Journal of translational medicine 2025 Mar 19;23(1):350
Journal of translational medicine 2025 Mar 19;23(1):350
Sterically chained amino acid-rich water-soluble carbon quantum dots as a robust tumor-targeted drug delivery platform.
Xie W, Wang H, Xu H, Su W, Yuan T, Chang J, Bai Y, Fan Y, Zhang Y, Li Y, Li X, Fan L
Nature communications 2025 Mar 19;16(1):2716
Nature communications 2025 Mar 19;16(1):2716
Chlorogenic acid induces hepatocellular carcinoma cell ferroptosis via PTGS2/AKR1C3/GPX4 axis-mediated reprogramming of arachidonic acid metabolism.
Wu L, Chen HY, Zhang JT, Yang RY, Wang ZB, Xue PS, Peng W, Li KX, Gao WH, Zeng PH
World journal of gastrointestinal oncology 2025 Mar 15;17(3):98844
World journal of gastrointestinal oncology 2025 Mar 15;17(3):98844
Transmembrane protein 176B promotes epithelial-mesenchymal transition in colorectal cancer through inflammasome inhibition.
Qian W, Xu CY, Hong W, Li ZM, Xu DG
World journal of gastrointestinal oncology 2025 Mar 15;17(3):97673
World journal of gastrointestinal oncology 2025 Mar 15;17(3):97673
Crip2 affects vascular development by fine-tuning endothelial cell aggregation and proliferation.
Yang S, Zhang X, Li X, Li H
Cellular and molecular life sciences : CMLS 2025 Mar 13;82(1):110
Cellular and molecular life sciences : CMLS 2025 Mar 13;82(1):110
Starvation-induced HBP metabolic reprogramming and STAM2 O-GlcNAcylation facilitate bladder cancer metastasis.
Feng Z, Mei Y, Chen H, Li L, Jin T, Li X, Gou X, Chen Y
Scientific reports 2025 Mar 12;15(1):8480
Scientific reports 2025 Mar 12;15(1):8480
The feedback loop between miR-222-3p and ZEB1 harnesses metastasis in renal cell carcinoma.
Wang F, Li L, Sun X, Cai X, Wang J, Luo H, Wang Y, Ni D, Wang D
Cell death discovery 2025 Mar 12;11(1):97
Cell death discovery 2025 Mar 12;11(1):97
RBM10 deficiency promotes brain metastasis by modulating sphingolipid metabolism in a BBB model of EGFR mutant lung adenocarcinoma.
Xu G, An B, Wang R, Pan B, Hao H, Ren X, Jing Z, Gao W, Li Y, Jin Y, Lin E, Shang L, Jia D, Yu Y
Journal of experimental & clinical cancer research : CR 2025 Mar 11;44(1):95
Journal of experimental & clinical cancer research : CR 2025 Mar 11;44(1):95
Ginsenoside Rh4 inhibits colorectal cancer via the modulation of gut microbiota-mediated bile acid metabolism.
Bai X, Duan Z, Deng J, Zhang Z, Fu R, Zhu C, Fan D
Journal of advanced research 2025 Jun;72:37-52
Journal of advanced research 2025 Jun;72:37-52
miR-135b-5p/PDE3B Axis Regulates Gemcitabine Resistance in Pancreatic Cancer Through Epithelial-Mesenchymal Transition.
Fu Y, Chen L, Lv N, Wang J, Yu S, Fang Q, Xin W
Molecular carcinogenesis 2025 Jun;64(6):1119-1130
Molecular carcinogenesis 2025 Jun;64(6):1119-1130
Granzyme B Promotes Proliferation, Migration and EMT Process in Gastric Cancer.
Lu Z, Huang X, Shen Q, Chen E, Feng Y
Biochemical genetics 2025 Jun;63(3):2513-2529
Biochemical genetics 2025 Jun;63(3):2513-2529
Identification and Validation of Basement Membrane Related LncRNA Signatures as a Novel Prognostic Model for Hepatocellular Carcinoma.
Liu X, Lv C, Zheng J, Xiao J, He N, Du J, Yang X, Gu H
Biochemical genetics 2025 Jun;63(3):2100-2119
Biochemical genetics 2025 Jun;63(3):2100-2119
Cancer-associated fibroblasts promote growth and dissemination of esophageal squamous cell carcinoma cells by secreting WNT family member 5A.
Yao L, Zhou C, Liu L, He J, Wang Y, Wang A
Molecular and cellular biochemistry 2025 Jun;480(6):3857-3872
Molecular and cellular biochemistry 2025 Jun;480(6):3857-3872
Metformin Attenuates Partial Epithelial-Mesenchymal Transition in Salivary Gland Inflammation via PI3K/Akt/GSK3β/Snail Signaling Axis.
Peng B, Wang L, Pan S, Kang J, Wei L, Li B, Cheng Y
Inflammation 2025 Jun;48(3):1525-1537
Inflammation 2025 Jun;48(3):1525-1537
Effects of the S1P/S1PR1 Signaling Pathway on High Glucose-Induced NRK-52E Epithelial-Mesenchymal Transition Via Regulation of ROS/NLRP3.
Tian J, Chen J, Sun Q, Huang T, Xu H, Wang J, Ma Z
Inflammation 2025 Jun;48(3):1285-1299
Inflammation 2025 Jun;48(3):1285-1299
LncRNA MKLN1-AS promotes glioma tumorigenesis and growth via activating the Hippo pathway through miR-126-5p/TEAD1 axis.
Chen S, Tu S, Huang Y, Lin H, Wang Y, Dai X
Naunyn-Schmiedeberg's archives of pharmacology 2025 Jun;398(6):6787-6799
Naunyn-Schmiedeberg's archives of pharmacology 2025 Jun;398(6):6787-6799
Glycated ECM Derived Carbon Dots Inhibit Tumor Vasculogenic Mimicry by Disrupting RAGE Nuclear Translocation and Its Interaction With HMGB1.
Zheng S, Zhang X, Yang F, Chang Z, Han J, Zhang H, Liu H, Sun T
Advanced materials (Deerfield Beach, Fla.) 2025 Jun;37(24):e2419540
Advanced materials (Deerfield Beach, Fla.) 2025 Jun;37(24):e2419540
Bioinspired hydrogel for sustained minocycline release: A superior periodontitis solution.
Liu S, Zheng W, Wang L, Zhang Y, Feng K, Zhang Y, Yang H, Xiao Y, Sun C, Liu X, Lu B, Yin X
Materials today. Bio 2025 Jun;32:101638
Materials today. Bio 2025 Jun;32:101638
Establishment of Long-Term Expansion Culture for Primary Murine Nasopharyngeal Cells.
Liu X, Tian Y, Zou Y, Fu Y, Zheng C, Duan T, Chen M, Bao J, Wang X, Ding RB, Zhou X
Tissue engineering. Part C, Methods 2025 Jun;31(6):221-229
Tissue engineering. Part C, Methods 2025 Jun;31(6):221-229
GJB2 as a novel prognostic biomarker associated with immune infiltration and cuproptosis in ovarian cancer.
Lei H, Guo K, Shu G, Wang M, Li Y, Tan Z, Pan Q, Yin G
Apoptosis : an international journal on programmed cell death 2025 Jun;30(5-6):1589-1613
Apoptosis : an international journal on programmed cell death 2025 Jun;30(5-6):1589-1613
Mechanistic study of Liquiritigenin inhibiting bladder cancer cell proliferation and migration by regulating STING1.
Li W, Yin Q, Qiu Y, Liu J, Wang J, Li C, Zhang D, Zhang P, Lv H, Lv Y, Wang Y
Cancer genetics 2025 Jun;294-295:156-170
Cancer genetics 2025 Jun;294-295:156-170
Hippo Pathway Regulates Cell Proliferation in Skin Epidermis Exposed to Mechanical Forces.
Ledwon JK, Progri B, Applebaum SA, Vignesh O, Yau A, Aguilar AH, Tepole AB, Gosain AK
Journal of cellular and molecular medicine 2025 Jun;29(12):e70674
Journal of cellular and molecular medicine 2025 Jun;29(12):e70674
LncRNA SNHG14 Regulated by ZNF460 Promotes Gastric Cancer Progression and Metastasis by Targeting the miR-206/FNDC3A Axis.
Liu B, Lu T, Zhang G, Dong X, Yu M, Cai H
Journal of cellular and molecular medicine 2025 Jun;29(11):e70652
Journal of cellular and molecular medicine 2025 Jun;29(11):e70652
Charge-reversed small extracellular vesicles from human adipose-derived mesenchymal stromal cells attenuate renal fibrosis postacute kidney injury by inhibiting epithelial-mesenchymal transition progression in SD rat model.
Ping W, Xu X, Jiang Y, Yang R, Xu L
Cytotherapy 2025 Jun;27(6):753-765
Cytotherapy 2025 Jun;27(6):753-765
Rotenone adaptation promotes migration and invasion of p53-wild-type colon cancer through lipid metabolism.
Shi Y, Cao Z, Ge L, Lei L, Tao D, Zhong J, Xu D, Geng T, Li X, Li Z, Xing S, Wu X, Wang Z, Li L
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2025 Jun;27(6):2557-2567
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2025 Jun;27(6):2557-2567
Resveratrol interrupts Wnt/β-catenin signalling in cervical cancer by activating ten-eleven translocation 5-methylcytosine dioxygenase 1.
Ren J, Xie L, Zhu X, Chen X, Wei L, Xu D, Qiao K, Min S, Ding Y, Tan Y
Cytokine 2025 Jun;190:156930
Cytokine 2025 Jun;190:156930
MBD2 promotes epithelial-to-mesenchymal transition (EMT) and ARDS-related pulmonary fibrosis by modulating FZD2.
Zhou Y, Yang G, Liu J, Yao S, Jia J, Tang X, Gong X, Wan F, Wu R, Zhao Z, Liang H, Liu L, Liu Q, Xie S, Long X, Xiang X, Wang G, Xiao B
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167798
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167798
LncRNA MIR503HG regulates NETs-mediated NLRP3 inflammasome activation and NSCLC metastasis by enhancing the ubiquitination of C/EBPβ.
Ye X, Fang C, Hong W, Qian X, Yu B, Zhou B, Yao X, Chen D, Shu C, Luo C, Wang Y, Li Y
Clinical and translational medicine 2025 Jun;15(6):e70342
Clinical and translational medicine 2025 Jun;15(6):e70342
Huang-Lian-Jie-Du decoction inhibits CD4+ T cell infiltration into CNS in MCAO rats by regulating BBB.
Chen C, Li C, Lan X, Ren Z, Zheng Y, Chen D, Xu W, Cui Y, Wang X, Cheng F, Wang Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156607
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156607
EFNA1 promotes the tumorigenesis and metastasis of cervical cancer by phosphorylation pathway and epithelial-mesenchymal transition.
Dong X, Chen X, Xue M, Zhang Y, Jiang P
Acta histochemica 2025 Jun;127(2):152236
Acta histochemica 2025 Jun;127(2):152236
The JAK1/STAT3 pathway mediates the effects of SERPINH1 on glioma EMT.
Wang S, Sun Z, Wang C, Zhang A, Zhang C, Hou S, Lin N, Li Q
International immunopharmacology 2025 Jun 5;157:114731
International immunopharmacology 2025 Jun 5;157:114731
TSP50 deficiency in neural stem cells aggravates colitis in mice by altering intestinal microbiome.
Li X, Jin R, Wang Z, Niu C, Song Z, Liu X, Huang J, Zhang H, Qian X, Gao F, Wang S, Yu C, Sun L, Huang Y, Zheng L, Wang G, Sun Y, Yang X, Bao Y, Li J
NPJ biofilms and microbiomes 2025 Jun 3;11(1):93
NPJ biofilms and microbiomes 2025 Jun 3;11(1):93
Oleanolic Acid Restores Drug Sensitivity in Sorafenib-resistant Hepatocellular Carcinoma: Evidence from In Vitro and In Vivo Studies.
Li T, Shen X, Zhang T, Ren J, Wang W, Wang D, Zhang P
Journal of clinical and translational hepatology 2025 Jun 28;13(6):469-483
Journal of clinical and translational hepatology 2025 Jun 28;13(6):469-483
Compound kushen injection inhibits breast cancer lung metastasis through regulating MTSS1/ARPC3/F-actin.
Wang YT, Liao QY, Dong YZ, Shu Y, Li XY, Li J, Sun RF, Su XS
Journal of ethnopharmacology 2025 Jun 26;350:120054
Journal of ethnopharmacology 2025 Jun 26;350:120054
The activation of cGAS-STING pathway promotes the epithelial-mesenchymal transition and inflammation in intrauterine adhesion.
Wu X, He L, Lin Y, Zheng Y, Mao R, Hu J, Yuan R, Ge H
International immunopharmacology 2025 Jun 26;159:114840
International immunopharmacology 2025 Jun 26;159:114840
Dexmedetomidine promotes colorectal cancer progression mediated by gamma-aminobutyric acid signaling.
Dong J, Wu Y, Che J, He Z, Zhang J
Cancer & metabolism 2025 Jun 23;13(1):33
Cancer & metabolism 2025 Jun 23;13(1):33
IGFBP2 Modulates Trophoblast Function and Epithelial-Mesenchymal Transition in Preeclampsia via the PI3K/AKT Signaling Pathway.
Meng S, Qin Y, Lyu C, Wang S
Current issues in molecular biology 2025 Jun 20;47(7)
Current issues in molecular biology 2025 Jun 20;47(7)
DDX5 super-enhancer promotes vasculogenic mimicry formation and metastasis in nasopharyngeal carcinoma by enhancing ADAM10 transcription.
Xia T, Yin H, Zhu Q, Zhang K, Xie H, Shan Y, Zhang S, Zhu R, Li K, Miao M, Lu Y, Wang Z, Zhao J, You Y, You B
Cell reports. Medicine 2025 Jun 17;6(6):102146
Cell reports. Medicine 2025 Jun 17;6(6):102146
Polystyrene nanoplastics aggravate house dust mite induced allergic airway inflammation through EGFR/ERK-dependent lung epithelial barrier dysfunction.
Wang Q, He W, Zhou Y, Feng R, Wang Y, Liu L, Yuan Y, Dai J, Liu Y, Zhang X
Ecotoxicology and environmental safety 2025 Jun 15;298:118329
Ecotoxicology and environmental safety 2025 Jun 15;298:118329
Mechanism of trypsin-mediated differentiation of pancreatic progenitor cells into functional islet-like clusters.
Gao L, Lai JS, Chen H, Qian LX, Hong WJ, Li LC
World journal of diabetes 2025 Jun 15;16(6):102727
World journal of diabetes 2025 Jun 15;16(6):102727
Taraxacum mongolicum total triterpenoids and taraxasterol ameliorate benign prostatic hyperplasia by inhibiting androgen levels, inflammatory responses, and epithelial-mesenchymal transition via the TGFβ1/Smad signalling pathway.
Chen L, Lin M, Wang Y, Wang X, Qi C, Fan R, Su S, Duan J, Liu F, Guo S, Duan JA
Journal of ethnopharmacology 2025 Jun 12;349:119995
Journal of ethnopharmacology 2025 Jun 12;349:119995
Nobiletin from Citrus reticulata Blanco alleviates pulmonary fibrosis through inhibiting the PI3K/AKT pathway and epithelial-mesenchymal transition.
Yu S, Liu K, Zhou F, Yang X, Zhang J, Yu K, Zhu Y, Qin L, Peng T, Zhang C, He Y
Journal of ethnopharmacology 2025 Jun 12;349:119965
Journal of ethnopharmacology 2025 Jun 12;349:119965
PDGFC secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and immunosuppression in lung adenocarcinoma.
Cui M, Ding X, Jiang Y, Zhang L, Cao W, Wang Y, Sheng Z, Sun W, Guo A, Gu L, Zhang X, Duan W, Shi L, Zhang B
Acta biochimica et biophysica Sinica 2025 Jun 11;57(10):1625-1635
Acta biochimica et biophysica Sinica 2025 Jun 11;57(10):1625-1635
Targeted Knockdown of Epithelial Estrogen Receptor α to Mitigate Ferroptosis and Epithelial-Mesenchymal Transition in Eosinophilic Asthma.
Zhang W, Zhang S, Hua L, Bai W, Qin L, Yue J, Wang D, Guo M, Wang X, Renz H, Chrysanthi S, Wang G, Chen Z, Dong H, Xie M
ACS nano 2025 Jun 10;19(22):21105-21117
ACS nano 2025 Jun 10;19(22):21105-21117
Role of the USP7/FOXO3A axis in environmentally relevant doses of arsenic-induced lung carcinogenesis: Insights from bioinformatics analysis and model of human epithelial cell malignant transformation.
Chen X, Wang Y, Liu Z, He Y, Gao H, Guan X, Chen L, Chen S, Xing X, Chen W, Li D, Wang Q
Ecotoxicology and environmental safety 2025 Jun 1;297:118224
Ecotoxicology and environmental safety 2025 Jun 1;297:118224
Curcumenol inhibits malignant progression and promotes ferroptosis via the SLC7A11/NF‑κB/TGF‑β pathway in triple‑negative breast cancer.
Li F, Qi Q, Qiao Y, Huang Y, Lu Y, Gu K, Liu H, Gao C, Liu S, Wu H
International journal of molecular medicine 2025 Jul;56(1)
International journal of molecular medicine 2025 Jul;56(1)
CYP2A6 suppresses hepatocellular carcinoma via inhibiting SRC/Wnt/β-Catenin pathway.
Liu YF, Feng LY, Zhang WY, Zhang X, Shao LJ, Zhao XM, Ji JB, Guo XL
Acta pharmacologica Sinica 2025 Jul;46(7):2029-2040
Acta pharmacologica Sinica 2025 Jul;46(7):2029-2040
SERPINB6 Promotes Epithelial-Mesenchymal Transition via PI3K/AKT/mTOR Signalling Pathway in Glioma.
Wang D, Wang H, Zheng W, Wang H, Yu W, Du Q
Journal of cellular and molecular medicine 2025 Jul;29(13):e70711
Journal of cellular and molecular medicine 2025 Jul;29(13):e70711
HucMSC-Ex alleviates inflammatory bowel disease by regulating O-GlcNAcylation modification of RACK1 in intestinal epithelial cells.
Liu Z, Yuan J, Din MA, Tian Y, Mao F
Colloids and surfaces. B, Biointerfaces 2025 Jul;251:114606
Colloids and surfaces. B, Biointerfaces 2025 Jul;251:114606
Increased SUMO-activating enzyme subunit 1 promotes glycolysis and fibrotic phenotype of diabetic nephropathy.
Wusiman R, Haimiti S, Abuduaini H, Yang M, Wang Y, Gu M, Sailike A, Gao L
Biochemical pharmacology 2025 Jul;237:116920
Biochemical pharmacology 2025 Jul;237:116920
Wenxia Changfu Formula inhibits NSCLC metastasis by halting TAMs-induced epithelial-mesenchymal transition via antagonisticallymodulating CCL18.
Bi Q, Wang M, Luo L, Zhang B, Lv S, Wang Z, Ji X
Chinese journal of natural medicines 2025 Jul;23(7):838-847
Chinese journal of natural medicines 2025 Jul;23(7):838-847
Nanoplastics Chronic Toxicity in Mice: Disturbing the Homeostasis of Tryptophan Metabolism in Gut-Lung-Microbiota Axis.
Wu Y, Yao Y, Shen Y, Bai H, Zhang L, Zhang C
Small (Weinheim an der Bergstrasse, Germany) 2025 Jul;21(26):e2412286
Small (Weinheim an der Bergstrasse, Germany) 2025 Jul;21(26):e2412286
A-485 alleviates fibrosis and apoptosis in kidney by disrupting tandem activation of acetylation and phosphorylation on STAT3.
Du C, Zhu Y, Duan J, Yang Y, Ren Y, Mu L, Yan Z, Li G, Wang H, Shi Y, Yao F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Jul;188:118217
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Jul;188:118217
Identification of the Oncogenic Role of MSH2 in the Stemness and Progression of Glioma Through Regulating Wnt Signaling Pathway.
Liu J, Chen J, Jiang L
Cancer medicine 2025 Jul;14(13):e70993
Cancer medicine 2025 Jul;14(13):e70993
Neoadjuvant Chemotherapy With Cisplatin Up-Regulates GSDMD to Enhance Oral Squamous Cell Carcinoma Metastasis Through MMP14-Mediated EMT Activation.
Huang Z, Jiang Q, Zhang Q, Lu N, Rui X, Chen R, Wang Y, Wang Y, Xu X, Huang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(25):e2501149
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(25):e2501149
LncRNA small nucleolar RNA host gene 1 (SNHG1) mediates acidic bile salt-induced EMT via the ULK1-Notch1 axis in Barrett's esophagus.
Zhou J, Zhao R, Li Z, Ma X, Jin W, Yuan Y, Li N, Liu B, Yang Y
Molecular biomedicine 2025 Jul 9;6(1):49
Molecular biomedicine 2025 Jul 9;6(1):49
Synergistic antitumor effects and mechanistic insight of hypericin-mediated photodynamic therapy combined with Olaparib in MCF-7 BRCA1 wild-type breast cancer cells.
Hu J, Yu Y, Song J
Medical oncology (Northwood, London, England) 2025 Jul 9;42(8):317
Medical oncology (Northwood, London, England) 2025 Jul 9;42(8):317
M6A-Methylated circRAPGEF5 drives lung adenocarcinoma progression and metastasis via IGF2BP2/NUP160-mediated autophagy suppression.
Ling L, Hu T, Zhou C, Dai Y, Hu L, Chen Y, Hu Z, Huang K, Chen J, Wang Y
Molecular cancer 2025 Jul 8;24(1):192
Molecular cancer 2025 Jul 8;24(1):192
P300-dependent acetylation of the FOXQ1 complex activates super-enhancers to promote colorectal cancer proliferation and metastasis.
Yang WD, Zhang ZH, Zhao MY, Shao K, Ma YF, Shen Q, Lu MR, Shao ZY, Xu JY, Cao MH, Meng S, Chu SF, Yong HM, Ding J, Bai J
Communications biology 2025 Jul 7;8(1):1016
Communications biology 2025 Jul 7;8(1):1016
Disintegrin Rhodostomin Mutant Ameliorates the Severity of Experimental Proliferative Vitreoretinopathy by Suppressing Both Integrin αvβ3 and α5β1.
Tsao YC, Chen SH, Ou YC, Chuang WJ, Yang CH, Lin CJ, Hsu SM
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 31;39(14):e70844
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jul 31;39(14):e70844
Bovine lactoferrin drives cell cycle arrest and alters the transcriptomic profile of NSCLC cells.
Su J, Zhao Y, Li M, Chen G, Liu C, Idris A, Ma Z, Zhang H
Scientific reports 2025 Jul 30;15(1):27850
Scientific reports 2025 Jul 30;15(1):27850
RhoJ promotes the progression of clear cell renal cell carcinoma via the TNF-α/NF-κB axis.
Feng J, Zheng B, Wang J, Xu Q, Ouyang Q, Li H, Jia T, Wang Y, Cai T, Feng Y, Zhang X, Li X, Ma X
Translational andrology and urology 2025 Jul 30;14(7):1849-1864
Translational andrology and urology 2025 Jul 30;14(7):1849-1864
Establishing dorsal-ventral patterning in human neural tube organoids with synthetic organizers.
Luo T, Liu C, Cheng T, Zhao GQ, Huang Y, Luan JY, Guo J, Liu X, Wang YF, Dong Y, Xiao Y, He E, Sun RZ, Chen X, Chen J, Ma J, Megason S, Ji J, Xu PF
Cell stem cell 2025 Jul 3;32(7):1071-1086.e8
Cell stem cell 2025 Jul 3;32(7):1071-1086.e8
The value of acetylation reader YEATS2 in hepatocellular carcinoma management.
Shi Y, Xiao Q, Xiao W, Kang J, Zhou Q, Jia H, Chen Y, Huang S
Scientific reports 2025 Jul 29;15(1):27613
Scientific reports 2025 Jul 29;15(1):27613
CRP and HNF1A collaborate to regulate the progression of laryngeal cancer through the Wnt signaling pathway.
Zhao Z, Zhu X, Xu J, Song P, Sun Y, Yang Z, Wang L, Zhang J, Zhao R, Chen X, Li W, Tian L, Liu M
Functional & integrative genomics 2025 Jul 25;25(1):160
Functional & integrative genomics 2025 Jul 25;25(1):160
GPX3 promotes cisplatin resistance in TNBC by manipulating ROS-TGFB1-ZEB2.
Hu Q, Chen Q, Yang W, Ren A, Tan J, Huang T
Cell communication and signaling : CCS 2025 Jul 25;23(1):355
Cell communication and signaling : CCS 2025 Jul 25;23(1):355
Engineered tumor microspheres via microfluidics and decellularized extracellular matrix for high-throughput organoid-based drug screening.
Jin J, Chen W, Li J, Yang J, Dai R, Tang J, Li M, Chen Y, Zhang C, Liu J
Biofabrication 2025 Jul 25;17(4)
Biofabrication 2025 Jul 25;17(4)
Terrestrosin D promotes autophagy and apoptosis of breast cancer cells through PSMD1-dependent activation of P53 pathway.
Jia LL, Wu CJ, Ye PW, Zhang Q, Liu H, Li TP, Hu XL
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156883
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156883
Curzerene suppresses epithelial-mesenchymal transition in gastric precancerous lesion cells through targeted regulation of YAP via the long non-coding RNA AFAP1-AS1.
Zhou X, Zhang C, Shen W, Zhuang R, Liu S, Liu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156879
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156879
Qingshu Yiqi decoction ameliorates exertional heat stroke-induced intestinal barrier injury via NF-κB/MLC pathway and gut microbiota.
Ma W, Wang M, Chen J, Wang Y, Chen J, Pei Y, Gong Y, You J, Cao Y, Zhou J, Ma J, Chang W, Zhu H, Song Q, Li L, Xu S, Zhu H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156723
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156723
EphrinB2 alleviates tubulointerstitial fibrosis in diabetic kidney disease.
Ni L, Zhou Q, Gao X, Chen F, Yusufu A, Chen JH, Yuan C, Wu X
Journal of translational medicine 2025 Jul 24;23(1):821
Journal of translational medicine 2025 Jul 24;23(1):821
Phosphodiesterase 1A physically interacts with YTHDF2 and reinforces the progression of non-small cell lung cancer.
Zhang C, Zhang Z, Wu Y, Wu Y, Cheng J, Luo K, Li Z, Zhang M, Wang J, Zhang X, Li Y
eLife 2025 Jul 24;13
eLife 2025 Jul 24;13
Growth Hormone Signaling in Bladder Cancer: Transcriptomic Profiling of Patient Samples and In Vitro Evidence of Therapy Resistance via ABC Transporters and EMT Activation.
Davis E, Caggiano LJ, Munholland H, Basu R, Berryman DE, Kopchick JJ
International journal of molecular sciences 2025 Jul 23;26(15)
International journal of molecular sciences 2025 Jul 23;26(15)
DSS1 inhibits autophagy to activate epithelial-mesenchymal transition in a pro-metastatic niche of renal cell carcinoma.
Chen X, Liu Q, Wu J, Zhou P, Zhao M, Song J
Nature communications 2025 Jul 23;16(1):6769
Nature communications 2025 Jul 23;16(1):6769
Molecular function validation and prognostic value analysis of the cuproptosis-related gene ferredoxin 1 in papillary thyroid carcinoma.
He S, Peng W, Hu X, Chen Y
Scientific reports 2025 Jul 23;15(1):26845
Scientific reports 2025 Jul 23;15(1):26845
Gut microbiota-bile acid crosstalk contributes to calcium oxalate nephropathy through Hsp90α-mediated ferroptosis.
Liu L, Ma Y, Jian Z, Liao B, Li Y, Lin L, Wang M, Chen J, Wei J, Yang M, Liu Y, Yuan Y, Wen J, Xiang L, Qi S, Jin X, Wang K
Cell reports 2025 Jul 22;44(7):115936
Cell reports 2025 Jul 22;44(7):115936
P4HA2 promotes the progression of papillary thyroid cancer by enhancing degradation of IκBα to activate NF-κB signaling pathway.
Li R, Zhao M, Sun M, Wu Y, Miao C, Fangyu L, Wu M, Shi X, Lu J, Yue X
Cancer cell international 2025 Jul 2;25(1):249
Cancer cell international 2025 Jul 2;25(1):249
XBP1 promotes endometrial fibrosis through cGAS-STING signaling pathway in intrauterine adhesion.
Wu X, He L, Lin Y, Zheng Y, Jiang P, Tian C, Mao R, Yang B, Shi Y, Ge H, Hu J, Yuan R
Scientific reports 2025 Jul 2;15(1):23299
Scientific reports 2025 Jul 2;15(1):23299
Cathepsin S mediates the disruption of airway epithelial Pannexin 1 via an Akt-dependent pathway in an LPS-induced murine model of acute lung injury.
Yang C, Fu L, Li R, Tang H, Chen Z, Gan S, Sun J, Li S, Li J, Yao L
Experimental cell research 2025 Jul 15;450(2):114663
Experimental cell research 2025 Jul 15;450(2):114663
Secreted phosphoprotein 1 promotes the activation of keloid fibroblasts via the CD44/TGF-β1/Smad pathway.
Tu Y, Xiong Y, Liu O, Peng Y
Experimental cell research 2025 Jul 15;450(2):114658
Experimental cell research 2025 Jul 15;450(2):114658
Elevated SGO2 expression in lung adenocarcinoma promotes migration and invasion via MAD2 and correlates with poor prognosis.
Sun M, Zhou W, Wei G, Lv M, Sun Y, Zhao H, Zhu C
Scientific reports 2025 Jul 15;15(1):25642
Scientific reports 2025 Jul 15;15(1):25642
Integrative proteomics and metabolomics analyses reveals the regulation of autophagy and ferroptosis by RAB10 through Slc37a2/mTOR pathway in breast cancer.
Ji Y, Li R, Tang G, Xiao Y, Ye R, Shi J, Geng C, Ran R, Zhu C, Wang W, Chen C, Yang Q
Cellular and molecular life sciences : CMLS 2025 Jul 14;82(1):275
Cellular and molecular life sciences : CMLS 2025 Jul 14;82(1):275
Keratin 6A Overexpression in the Lymphovascular Invasion-Associated Tumor Subgroup Promotes Progression of Triple-Negative Breast Cancer.
Luo W, Zou Y, Jiang Y, Ma X, Guo S, Wang Y, Liu Y, Hai L, Jia W, Liu W, Meng R, Cao X, Ruan X, Yu Y
Cancer research and treatment 2025 Jul 14;
Cancer research and treatment 2025 Jul 14;
Enhancing the therapeutic efficacy of gemcitabine in bladder cancer through TGF-β1 inhibition and pluronic F-127-based microsphere delivery.
Xiong Y, Li Y, Chen L, Chen M, He W, Qi L
Journal of biological engineering 2025 Jul 11;19(1):62
Journal of biological engineering 2025 Jul 11;19(1):62
TMEM150A overexpression was associated with poor prognosis and cancer progression in glioma verified by comprehensive analysis and cell experiments.
Xu HQ, Zhao D, Xu SH, Mao R, Yang WQ, Han Q
Scientific reports 2025 Jul 11;15(1):25017
Scientific reports 2025 Jul 11;15(1):25017
MTMR14 depletion aggravates intrapulmonary inflammation and emphysema in experimental COPD through activating macrophage M1 polarization.
Zhang J, Zhan Y, Deng Z, Chen S, Yang R, Zhang Y, Fu H, Huang Q, Wu J, Gu Y, Xie J
Respiratory research 2025 Jul 10;26(1):238
Respiratory research 2025 Jul 10;26(1):238
Biological and metabolomic insights into RACGAP1-mediated growth and progression of clear cell renal cell carcinoma.
Li W, Gan L, Zang W, Chen Y, Xu B
American journal of physiology. Cell physiology 2025 Jul 1;329(1):C283-C297
American journal of physiology. Cell physiology 2025 Jul 1;329(1):C283-C297
DNMT3B aggravated renal fibrosis in diabetic kidney disease via activating Wnt/β-catenin signaling pathway.
Qu L, Wang T, Kong J, Wu X, Li Q, Long T, An X, Lu Y, Mu Y, Ran Y, Guo B, Shi M
Scientific reports 2025 Jul 1;15(1):21070
Scientific reports 2025 Jul 1;15(1):21070
FOXL2 Knockdown Inhibits the Progression of Endometriosis.
Zhang B, Li SJ, Yuan H, Cong SS, Zhao SJ, Yang XJ
American journal of reproductive immunology (New York, N.Y. : 1989) 2025 Jan;93(1):e70043
American journal of reproductive immunology (New York, N.Y. : 1989) 2025 Jan;93(1):e70043
Complement factor H drives idiopathic pulmonary fibrosis by autocrine C3 regulation, suppressing macrophage phagocytosis and enhancing fibrotic progression.
Ma D, Hua Y, Lu Y
Biochemical and biophysical research communications 2025 Jan;745:151220
Biochemical and biophysical research communications 2025 Jan;745:151220
Network pharmacology, molecular docking, and experimental verification to reveal the mechanism of colquhounia root tablet in the treatment of diabetic nephropathy.
Chen D, Wang S, Sun Z, Zhang X, Chong N, Shu J, Wang Q, Xu Y
Biochemical and biophysical research communications 2025 Jan;745:151086
Biochemical and biophysical research communications 2025 Jan;745:151086
Wnt5a promotes VM formation by modulating the stemness and EMT progression of prostate cancer cell.
Liu B, Li X, Wang S, Jia H, Zhang X, Dong Q, Li J
Translational oncology 2025 Jan;51:102155
Translational oncology 2025 Jan;51:102155
Slit2 Promotes H(2)O(2)-Induced Lens Epithelial Cells Oxidative Damage and Age-Related Cataract.
Fu L, Yang Q, Han Y, Sun F, Jin J, Wang J
Current eye research 2025 Jan;50(1):41-50
Current eye research 2025 Jan;50(1):41-50
Centromere protein K enhances the activation of YAP1/TAZ signal cascade to drive the progression of clear cell renal cell carcinoma.
Nan N
Toxicology and applied pharmacology 2025 Jan;494:117181
Toxicology and applied pharmacology 2025 Jan;494:117181
EML4-ALK G1202R and EML4-ALK L1196M mutations induce crizotinib resistance in non-small cell lung cancer cells through activating epithelial-mesenchymal transition mediated by MDM2/MEK/ERK signal axis.
Yang Y, Yang H, Gao Y, Yang Q, Zhu X, Miao Q, Xu X, Li Z, Zuo D
Cell biology international 2025 Jan;49(1):55-67
Cell biology international 2025 Jan;49(1):55-67
ATF1 regulates MAL2 expression through inhibition of miR-630 to mediate the EMT process that promotes cervical cancer cell development and metastasis.
Cao Y, Peng Y, Tang Y
Journal of gynecologic oncology 2025 Jan;36(1):e11
Journal of gynecologic oncology 2025 Jan;36(1):e11
Dental pulp stem cell‑derived extracellular vesicles loaded with hydrogels promote osteogenesis in rats with alveolar bone defects.
He X, Chu XY, Chen X, Xiang YL, Li ZL, Gao CY, Luan YY, Yang K, Zhang DL
Molecular medicine reports 2025 Jan;31(1)
Molecular medicine reports 2025 Jan;31(1)
NKD2 as a Mediator of IFIX Antioncogene-Induced Wnt Signalling and Epithelial-Mesenchymal Transition in Human OSCC.
Wang S, Fan H, Bai J
Journal of cellular and molecular medicine 2025 Jan;29(2):e70342
Journal of cellular and molecular medicine 2025 Jan;29(2):e70342
Trametinib and M17, a novel small molecule inhibitor of AKT, display a synergistic antitumor effect in triple negative breast cancer cells through the AKT/mTOR and MEK/ERK pathways.
Han H, Yang M, Wen Z, Mei F, Chen Q, Ma Y, Lai X, Zhang Y, Fang R, Yin T, Sun S, Wang X, Qi J, Lin H, Yang Y
Bioorganic chemistry 2025 Jan;154:107981
Bioorganic chemistry 2025 Jan;154:107981
Wenshen Yiqi Granule Alleviates Chronic Obstructive Pulmonary Disease via the Long Noncoding RNA-XIST/MicroRNA-200c-3p Axis.
Deng H, Zhu S, Yu F, Song X, Jin X, Ding X
Pulmonary circulation 2025 Jan;15(1):e70040
Pulmonary circulation 2025 Jan;15(1):e70040
NAP1L5 promotes epithelial-mesenchymal transition by regulating PEG10 expression in acute myeloid leukaemia.
Wu H, Luo H, Wang M, Du Y, Li J
Leukemia research 2025 Jan;148:107623
Leukemia research 2025 Jan;148:107623
Modified Zuojin pill alleviates gastric precancerous lesions by inhibiting glycolysis through the HIF-1α pathway.
Liu S, Ji H, Zhang T, Huang J, Yin X, Zhang J, Wang P, Wang F, Tang X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156255
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156255
TIFA enhances glycolysis through E2F1 and promotes the progression of glioma.
Liu Z, He M, Yu Z, Ma L, Wang X, Ning F
Cellular signalling 2025 Jan;125:111498
Cellular signalling 2025 Jan;125:111498
Morusin Reverses Epithelial-Mesenchymal Transition in Gallbladder Cancer Cells by Regulating STAT3/HIF-1α Signaling.
Ji L, Chai Y, Tong C, Hu Y, Li J, Lu B, Yu J
Chemical biology & drug design 2025 Jan;105(1):e70054
Chemical biology & drug design 2025 Jan;105(1):e70054
Estrogen Receptor β Activation Mitigates Colitis-associated Intestinal Fibrosis via Inhibition of TGF-β/Smad and TLR4/MyD88/NF-κB Signaling Pathways.
Ling F, Chen Y, Li J, Xu M, Song G, Tu L, Wang H, Li S, Zhu L
Inflammatory bowel diseases 2025 Jan 6;31(1):11-27
Inflammatory bowel diseases 2025 Jan 6;31(1):11-27
Cromolyn sodium reduces LPS-induced pulmonary fibrosis by inhibiting the EMT process enhanced by MC-derived IL-13.
Tan C, Zhou H, Xiong Q, Xian X, Liu Q, Zhang Z, Xu J, Yao H
Respiratory research 2025 Jan 6;26(1):3
Respiratory research 2025 Jan 6;26(1):3
MYBL2 promotes proliferation of clear cell renal cell carcinoma by regulating TOP2A and activating AKT/mTOR signaling pathway.
Huang Y, Xi X, Ye Z, Zhang C, Jiang Y, Yu F, Huang G
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jan 31;39(2):e70330
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Jan 31;39(2):e70330
Pharmacological effects and mechanisms of danlong oral liquid in asthma airway remodeling: Insights from serum medicinal chemistry, network pharmacology, and experimental validation.
Liu B, Xiang M, Zhou M, Li C, Xin H, Zhang S, Lin J
Journal of ethnopharmacology 2025 Jan 31;340:119259
Journal of ethnopharmacology 2025 Jan 31;340:119259
Emodin reverses sorafenib resistance in hepatocellular carcinoma by inhibiting epithelial-mesenchymal transition via the Akt signaling pathway.
Wang Q, Zhang J
Translational cancer research 2025 Jan 31;14(1):286-295
Translational cancer research 2025 Jan 31;14(1):286-295
Xihuang pill suppresses breast cancer malignancy by inhibiting TGF-β signaling and acquires chemotherapy benefits.
Hong W, Tang H, Wang D, Qian D, Xu Y, Zheng Y, Li S, Zheng Q, Meng X, Liu X
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):119000
Journal of ethnopharmacology 2025 Jan 30;337(Pt 3):119000
Formin protein DAAM1 positively regulates PD-L1 expression via mediating the JAK1/STAT1 axis in pancreatic cancer.
Xu R, Wan M, Pan J, Mei J, Zhou J, Shen Y, Yang J, Zhu Y, Sun J
Cancer cell international 2025 Jan 29;25(1):28
Cancer cell international 2025 Jan 29;25(1):28
DRAM1 enhances the proliferation and metastasis of gastric cancer through the PI3K/AKT/mTOR signaling pathway and energy metabolism.
Wu X, Li Y, Wang W, Xu J, Zhao B, Sun W, Ge D, Xiong L, Dou X, Zou X, Wang L, Chen M
Scientific reports 2025 Jan 28;15(1):3542
Scientific reports 2025 Jan 28;15(1):3542
Synergistic inhibition of colorectal cancer progression by silencing Aurora A and the targeting protein for Xklp2.
Sheng GX, Zhang YJ, Shang T
World journal of gastrointestinal surgery 2025 Jan 27;17(1):97148
World journal of gastrointestinal surgery 2025 Jan 27;17(1):97148
UHRF1 promotes epithelial-mesenchymal transition mediating renal fibrosis by activating the TGF-β/SMAD signaling pathway.
Yang L, Si P, Kuerban T, Guo L, Zhan S, Zuhaer Y, Zuo Y, Lu P, Bai X, Liu T
Scientific reports 2025 Jan 27;15(1):3346
Scientific reports 2025 Jan 27;15(1):3346
Co-exposure to polyethylene microplastics and house dust mites aggravates airway epithelial barrier dysfunction and airway inflammation via CXCL1 signaling pathway in a mouse model.
Hu JQ, Wang CC, Ma RX, Qi SQ, Fu W, Zhong J, Cao C, Zhang XL, Liu GH, Gao YD
International immunopharmacology 2025 Jan 27;146:113921
International immunopharmacology 2025 Jan 27;146:113921
A novel USP4 inhibitor that suppresses colorectal cancer stemness by promoting β-catenin and Twist1 degradation.
Li F, Zhou Y, Lin X, Zhang Y, Hu Q, Zhao E, Li H, Pan X, Shu F, Zhang K, Huang C, Tang N, Liao W
Journal of translational medicine 2025 Jan 24;23(1):114
Journal of translational medicine 2025 Jan 24;23(1):114
Discovery of Novel Small-Molecule Inhibitors Disrupting the MTDH-SND1 Protein-Protein Interaction.
Shen H, Ding J, Ji J, Hu L, Min W, Hou Y, Wang D, Chen Y, Wang L, Zhu Y, Wang X, Yang P
Journal of medicinal chemistry 2025 Jan 23;68(2):1844-1862
Journal of medicinal chemistry 2025 Jan 23;68(2):1844-1862
Wearable electrodriven switch actively delivers macromolecular drugs to fundus in non-invasive and controllable manners.
Qin X, Shi H, Li H, Chu B, Zhang J, Wen Z, Sun X, Wang H, He Y
Nature communications 2025 Jan 2;16(1):33
Nature communications 2025 Jan 2;16(1):33
A tunable human intestinal organoid system achieves controlled balance between self-renewal and differentiation.
Yang L, Wang X, Zhou X, Chen H, Song S, Deng L, Yao Y, Yin X
Nature communications 2025 Jan 2;16(1):315
Nature communications 2025 Jan 2;16(1):315
Time-series single-cell transcriptomic profiling of luteal-phase endometrium uncovers dynamic characteristics and its dysregulation in recurrent implantation failures.
Cao D, Liu Y, Cheng Y, Wang J, Zhang B, Zhai Y, Zhu K, Liu Y, Shang Y, Xiao X, Chang Y, Lee YL, Yeung WSB, Huang Y, Yao Y
Nature communications 2025 Jan 2;16(1):137
Nature communications 2025 Jan 2;16(1):137
Hypoxia-induced circPLOD2a/b promotes the aggressiveness of glioblastoma by suppressing XIRP1 through binding to HuR.
Yu A, Wang Y, Duan C, Qin J, Liao M, Zhu H, Lei J, Liu J, Yang Z, Yu L, Gui H, Xin J, Tao W, Bao W, Dong Z
Communications biology 2025 Jan 17;8(1):71
Communications biology 2025 Jan 17;8(1):71
Blue light promotes conjunctival epithelial-mesenchymal transition and collagen deposition through ITGB4.
Yang Q, Chen K, Chen S, Wang Y, Xia Y, Chen J, Shen Y
Ecotoxicology and environmental safety 2025 Jan 15;290:117584
Ecotoxicology and environmental safety 2025 Jan 15;290:117584
MicroRNA-150-3p enhances the antitumour effects of CGP57380 and is associated with a favourable prognosis in non-small cell lung cancer.
Zheng H, Fan S, Luo J, Wen Q, Zang H
Scientific reports 2025 Jan 15;15(1):1973
Scientific reports 2025 Jan 15;15(1):1973
Photo-Crosslinking Hydrogel Based on Porcine Small Intestinal Submucosa Decellularized Matrix/Fish Collagen/GelMA for Culturing Small Intestinal Organoids and Repairing Intestinal Defects.
Jia Z, Wang Z
International journal of molecular sciences 2025 Jan 14;26(2)
International journal of molecular sciences 2025 Jan 14;26(2)
EIF4A3-Mediated circ_0008126 Inhibits the Progression and Metastasis of Gastric Cancer by Modulating the APC/β-Catenin Pathway.
Wang Z, Chen W, Wang Z, Dai X
Cancers 2025 Jan 14;17(2)
Cancers 2025 Jan 14;17(2)
Myristoylated Eepd1 Enhances Lipolysis and Thermogenesis through PKA Activation to Combat Obesity.
Chen S, Wang Y, Zhou Q, Qian Q, Jiang Q, Liu C, Liu Y, Zhou P, Xiong J, Zhang Y, Wang N, Li YE, Yin L, Yang H, Liu J
Nature communications 2025 Jan 14;16(1):651
Nature communications 2025 Jan 14;16(1):651
Molecule interacting with CasL-2 enhances tumor progression and alters radiosensitivity in cervical cancer.
Teng Y, Zhao H, Xue G, Zhang G, Huang Y, Guo W, Zou K, Zou L
Journal of translational medicine 2025 Jan 11;23(1):44
Journal of translational medicine 2025 Jan 11;23(1):44
Bisphenol S exposure promotes stemness of triple-negative breast cancer cells via regulating Gli1-mediated Sonic hedgehog pathway.
Yi K, Chen W, Zhou X, Xie C, Zhong C, Zhu J
Environmental research 2025 Jan 1;264(Pt 1):120293
Environmental research 2025 Jan 1;264(Pt 1):120293
SPHK1/S1PR1/PPAR-α axis restores TJs between uroepithelium providing new ideas for IC/BPS treatment.
Zhang J, Ge Q, Du T, Kuang Y, Fan Z, Jia X, Gu W, Chen Z, Wei Z, Shen B
Life science alliance 2025 Feb;8(2)
Life science alliance 2025 Feb;8(2)
circ_0004662 contributes to colorectal cancer progression by interacting with hnRNPM.
Zhang Y, Wang J, Quan R, Lyu L
International journal of oncology 2025 Feb;66(2)
International journal of oncology 2025 Feb;66(2)
NEK2 Promotes ESCC Malignant Progression by Inhibiting Cellular Senescence via the FOXM1/c-Myc/p27 Signaling Pathway.
Li J, Wang Y, Wei S, Xu S, Dai S, Zhang L, Tian Z, Zhao L, Lv H
Molecular carcinogenesis 2025 Feb;64(2):244-259
Molecular carcinogenesis 2025 Feb;64(2):244-259
Novel Diagnostic Biomarker BST2 Identified by Integrated Transcriptomics Promotes the Development of Endometriosis via the TNF-α/NF-κB Signaling Pathway.
Jiang L, Wang S, Xia X, Zhang T, Wang X, Zeng F, Ma J, Fang X
Biochemical genetics 2025 Feb;63(1):354-377
Biochemical genetics 2025 Feb;63(1):354-377
β-Catenin mediated TAM phenotype promotes pancreatic cancer metastasis via the OSM/STAT3/LOXL2 axis.
Zhang Y, Zhu X, Chen L, Gao T, Chen G, Zhu J, Wang G, Zuo D
Neoplasia (New York, N.Y.) 2025 Feb;60:101096
Neoplasia (New York, N.Y.) 2025 Feb;60:101096
Epigenetic silencing of JAM3 promotes laryngeal squamous cell carcinoma development by inhibiting the Hippo pathway.
Jia Y, Liu J, Shi J, Zhang C, Wang X, Zhao L, Lou Y, Guan X, Huangfu H
Oncology reports 2025 Feb;53(2)
Oncology reports 2025 Feb;53(2)
Hypericin mediated photodynamic therapy induces ferroptosis via inhibiting the AKT/mTORC1/GPX4 axis in cholangiocarcinoma.
An W, Zhang K, Li G, Zheng S, Cao Y, Liu J
Translational oncology 2025 Feb;52:102234
Translational oncology 2025 Feb;52:102234
RNF144A-AS1 stabilizes TAF15 and promotes malignant biological behaviors of skin cutaneous melanoma.
Yang S, Sun Y, Wang N, Yang Z, Xing H, Jia J
Molecular and cellular biochemistry 2025 Feb;480(2):1155-1167
Molecular and cellular biochemistry 2025 Feb;480(2):1155-1167
Ilicicolin C suppresses the progression of prostate cancer by inhibiting PI3K/AKT/mTOR pathway.
Gan X, Luo X, Chen J, Fang W, Nie M, Lu H, Liu Y, Wang X
Molecular and cellular biochemistry 2025 Feb;480(2):1089-1104
Molecular and cellular biochemistry 2025 Feb;480(2):1089-1104
TWIST1 Regulates FOXM1/β-Catenin to Promote the Growth, Migration, and Invasion of Ovarian Cancer Cells by Activating MFAP2.
Zhao L, Song Q, Zheng C, Sun W, Chen Y
Journal of biochemical and molecular toxicology 2025 Feb;39(2):e70140
Journal of biochemical and molecular toxicology 2025 Feb;39(2):e70140
SETD7 promotes LC3B methylation and degradation in ovarian cancer.
Zhang Z, Li M, Hou Y, Huang T, Zhang B, Lin Q, Shao G
The Journal of biological chemistry 2025 Feb;301(2):108134
The Journal of biological chemistry 2025 Feb;301(2):108134
FBXO2 as a switch guides a special fate of tumor clones evolving into a highly malignant transcriptional subtype in oral squamous cell carcinoma.
Cheng J, Liu O, Bin X, Tang Z
Apoptosis : an international journal on programmed cell death 2025 Feb;30(1-2):167-184
Apoptosis : an international journal on programmed cell death 2025 Feb;30(1-2):167-184
PRELP inhibits colorectal cancer progression by suppressing epithelial-mesenchymal transition and angiogenesis via the inactivation of the FGF1/PI3K/AKT pathway.
Li X, Jiang Z, Li J, Yang K, He J, Deng Q, Xu S, Jiang Z, Liu F, Jiang Z
Apoptosis : an international journal on programmed cell death 2025 Feb;30(1-2):16-34
Apoptosis : an international journal on programmed cell death 2025 Feb;30(1-2):16-34
Organophosphate flame retardant triphenyl phosphate (TPhP) induced colonic fibrosis by bringing about epithelial-mesenchymal transition.
Peng C, Wang M, Zheng C, Zhang X, Chen Y, Wang L
Ecotoxicology and environmental safety 2025 Feb;291:117913
Ecotoxicology and environmental safety 2025 Feb;291:117913
Prenatal Perfluorooctanoic Acid (PFOA) exposure causes reproductive toxicity by disrupting the formation of transzonal projections (TZPs) and down-regulating Wnt4/β-catenin signaling pathway in progeny.
Du H, Song L, Zhao M, Zhao X, Mu R, Gao S, Zhang B, Wang J
Ecotoxicology and environmental safety 2025 Feb;291:117816
Ecotoxicology and environmental safety 2025 Feb;291:117816
The Oncopromoting Gene RBM6 Inhibits Prostate Tumour Cell Migration During Epithelial-to-Mesenchymal Transition.
Liu R, Liu Y, Zhang L, Li X, Li N, Lu F, Gao W, Jia Z, Huang Z, Yang J
Journal of cellular and molecular medicine 2025 Feb;29(3):e70397
Journal of cellular and molecular medicine 2025 Feb;29(3):e70397
Dedicator of cytokinesis protein 2 activates the epithelial-mesenchymal transition in renal fibrosis through the Rac1/PI3K/AKT pathway.
Jia Y, Sun J, Chen S, Bian Y, Jiang A, Liang H, Du X
Biochimica et biophysica acta. Molecular cell research 2025 Feb;1872(2):119894
Biochimica et biophysica acta. Molecular cell research 2025 Feb;1872(2):119894
LAMP3-mediated epithelial-mesenchymal transition promotes the invasion and excessive proliferation of fibroblast-like synoviocytes in rheumatoid arthritis.
Zhou W, Cheng H, Fan C, Zhou X, Chen W, Xie C, Hu Y, Chen Y, Wang X, Wu J
Journal of autoimmunity 2025 Feb;151:103359
Journal of autoimmunity 2025 Feb;151:103359
Yiqi Huayu Jiedu formula inhibits JAK2/STAT3-mediated partial EMT in treating chronic atrophic gastritis.
Yu W, Chen S, Guan X, He G, Zhang W, Zhang H, Huang S, Ye Z, Pan H, Zhong Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Feb;137:156356
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Feb;137:156356
HECW1-Mediated Ubiquitination of HIPK2 Drives Metastasis in Gastric Cancer Through the AKT Signaling Pathway.
Zhang G, Qu W, Huang X, Yi J, Gao H, He J, Xue W
Laboratory investigation; a journal of technical methods and pathology 2025 Feb;105(2):102202
Laboratory investigation; a journal of technical methods and pathology 2025 Feb;105(2):102202
Endoplasmic reticulum stress-related CLIP4 plays a procarcinogenic role in hepatocellular carcinoma: an integrated analysis.
Wang A, Yan S, Jiang W, Chen X, Huang Y, Zu X, Du X, Fan L, Liu J, Sun G
BMC cancer 2025 Feb 7;25(1):211
BMC cancer 2025 Feb 7;25(1):211
Non-lethal sonodynamic therapy mitigates hypertensive renal fibrosis through the PI3K/AKT/mTORC1-autophagy pathway.
Liu D, Wang H, Li J, Sheng S, Wang S, Tian Y
Scientific reports 2025 Feb 6;15(1):4534
Scientific reports 2025 Feb 6;15(1):4534
PTOV1 exerts pro-oncogenic role in colorectal cancer by modulating SQSTM1-mediated autophagic degradation of p53.
Fan Y, Li Y, Luo X, Xiang S, Hu J, Zhan J, Chang W, Deng R, Ran X, Zhang Y, Cai Y, Zhu W, Wang H, Liu Z, Wang D
Journal of translational medicine 2025 Feb 4;23(1):157
Journal of translational medicine 2025 Feb 4;23(1):157
MSC-exosomes pretreated by Danshensu extracts pretreating to target the hsa-miR-27a-5p and STAT3-SHANK2 to enhanced antifibrotic therapy.
Liang J, Zhao J, Yang L, Wang Q, Liao J, Li J, Zhuang W, Li F, He J, Tang Y, Chen H, Huang C
Stem cell research & therapy 2025 Feb 4;16(1):40
Stem cell research & therapy 2025 Feb 4;16(1):40
Discovery of Novel Aromatic Urea-Imidazole Salt Derivatives for Cancer Therapy via Targeting ERK1/2.
Wang M, Yang S, Li X, Zheng Y, Bai Y, Luo W, Zhu G, Chang J, Zhu B
Journal of medicinal chemistry 2025 Feb 27;68(4):4101-4132
Journal of medicinal chemistry 2025 Feb 27;68(4):4101-4132
SJB2-043, a USP1 Inhibitor, Suppresses A549 Cell Proliferation, Migration, and EMT via Modulation of PI3K/AKT/mTOR, MAPK, and Wnt Signaling Pathways.
Wu L, Yu M, Liang H, Lin L, Li H, Chen G, Muhetaer H, Li J, Wu B, Jia X, Dang Y, Zheng G, Li C
Current issues in molecular biology 2025 Feb 27;47(3)
Current issues in molecular biology 2025 Feb 27;47(3)
Molecular mechanism of Gancao Xiexin Decoction regulating EMT and suppressing hepatic metastasis of gastric cancer via the TGF-β1/SMAD pathway.
Liu W, Lu D, Jia S, Yang Y, Meng F, Du Y, Yang Y, Yuan L, Nan Y
Journal of ethnopharmacology 2025 Feb 27;342:119430
Journal of ethnopharmacology 2025 Feb 27;342:119430
PTPRO represses breast cancer lung metastasis by inhibiting the JAK2-YAP axis.
Xiong X, Liu J, Wu X, Yao Z, Meng Y, Liu S, Chen Y, Ren H, Gao S, Qiu X, Zhang H
Scientific reports 2025 Feb 27;15(1):7065
Scientific reports 2025 Feb 27;15(1):7065
The inhibition of ZC3H13 attenuates G2/M arrest and apoptosis by alleviating NABP1 m6A modification in cisplatin-induced acute kidney injury.
Sheng Q, Yu Q, Lu S, Yang M, Fan X, Su H, Kong Z, Gao Y, Wang R, Lv Z
Cellular and molecular life sciences : CMLS 2025 Feb 22;82(1):86
Cellular and molecular life sciences : CMLS 2025 Feb 22;82(1):86
Phosphorylation of FOXN3 by NEK6 promotes pulmonary fibrosis through Smad signaling.
Yu J, Li Y, Li Y, Liu X, Huo Q, Wu N, Zhang Y, Zeng T, Zhang Y, Li HY, Lian J, Zhou J, Moses EJ, Geng J, Lin J, Li W, Zhu X
Nature communications 2025 Feb 21;16(1):1865
Nature communications 2025 Feb 21;16(1):1865
Autocrine small extracellular vesicles induce tubular phenotypic transformation in diabetic nephropathy via miR-21-5p.
Zhang M, Lu Y, Wang L, Mao Y, Hu X, Chen Z
Gene 2025 Feb 20;938:149156
Gene 2025 Feb 20;938:149156
Hypoxia-Induced VGF Promotes Cell Migration and Invasion in Prostate Cancer via the PI3K/Akt Axis.
Wang L, Zhang T, Qian Y, Wu Y, Li T, Zheng Y, Luo C, Wu X, Chen T, Ou L
Frontiers in bioscience (Landmark edition) 2025 Feb 20;30(2):25522
Frontiers in bioscience (Landmark edition) 2025 Feb 20;30(2):25522
Interferon regulatory factor 5 attenuates kidney fibrosis through transcriptional suppression of Tgfbr1.
Xu X, Miao M, Zhu W, Zhang L, Jin Q, Li Y, Xu M, Jia Z, Zhang A, Wu M
International immunopharmacology 2025 Feb 20;148:114031
International immunopharmacology 2025 Feb 20;148:114031
A novel piperine derivative HJJ_3_5 inhibits colorectal cancer progression by modulating EMT signaling pathways.
Cheng W, Liu S, He J, Li H, Liu X, Hu Z, Wang X, Wu Z, Xu G, Liu W, Liu B
Biochemical and biophysical research communications 2025 Feb 16;749:151323
Biochemical and biophysical research communications 2025 Feb 16;749:151323
Constructing a highly sensitive duplex immunoassay using AuNPs and AgNPs as nanolabels for investigating the epithelial-mesenchymal transition occurring on circulating tumor cells with lung cancer patients.
Dai Y, He J, Zhou Y, Yu Y, Hui H, Guo L, Yin H
Biosensors & bioelectronics 2025 Feb 15;270:116947
Biosensors & bioelectronics 2025 Feb 15;270:116947
Multi-omics analysis reveals the impact of YAP/TEAD4-mediated EIF5A1 expression on mitochondrial apoptosis and bladder cancer progression.
Li KP, Wan S, Wang CY, Chen SY, Wang L, Liu SH, Yang L
BMC cancer 2025 Feb 11;25(1):234
BMC cancer 2025 Feb 11;25(1):234
Ultrasound nanobubble-based combinational strategies of loaded miR-107-3p and CD133 Ab for anti-PD-L1 and anti-hepatocellular cancer stem cells.
Zhang C, Chen Y, Han J, Liu R, Liu C, Zhao Y, Liu Y
International journal of pharmaceutics 2025 Feb 10;670:125140
International journal of pharmaceutics 2025 Feb 10;670:125140
Magnolol preserves the integrity of the intestinal epithelial barrier and mitigates intestinal injury through activation of PPAR γ in COPD rat.
Tao L, Zhang Q, Liu L, Wang K, Liu X, Li J, Zhao P
Journal of ethnopharmacology 2025 Feb 10;338(Pt 2):119068
Journal of ethnopharmacology 2025 Feb 10;338(Pt 2):119068
CircRNA circACTN4 Promotes the Progression of Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma by Targeting the miR-424-5p/NCAPG/Wnt Axis.
Shan J, Pu J, Chen X, Zhang Y, Li J, Qin L, Shi J, Zhou L, Deng Y
Clinical and experimental medicine 2025 Feb 1;25(1):47
Clinical and experimental medicine 2025 Feb 1;25(1):47
B7-H3 enhances the malignant phenotype of colorectal cancer by activating the Wnt/β-catenin pathway mediated by CYP1B1.
Liu X, Ding J, Zong Q, Mao Y
Tissue & cell 2025 Dec;97:103066
Tissue & cell 2025 Dec;97:103066
IMUP promotes fatty acid metabolism and lung cancer progression by regulating TGF-β/SMAD3 signaling pathway.
Wu S, Liu F, Yao X, Lei Y, Wang W
Tissue & cell 2025 Dec;97:103061
Tissue & cell 2025 Dec;97:103061
FOXA1 Transcriptional Repression of PLSCR1 Inhibits Tongue Squamous Cell Carcinoma Progression.
Wang J, Zhang C, Wang J, Wang L, Liu L, Duan C
Cell biochemistry and biophysics 2025 Dec;83(4):4551-4566
Cell biochemistry and biophysics 2025 Dec;83(4):4551-4566
TTK Defines a High-Risk Oral Squamous Cell Carcinoma Subtype Through Dual mTORC1/NF-κB Activation.
Jin H, Liu T, Guo Y, Bu W, Liu F, Hou Y
International dental journal 2025 Dec;75(6):103945
International dental journal 2025 Dec;75(6):103945
miR‑100‑5p and miR‑203a‑3p suppress esophageal squamous cell carcinoma progression by targeting FKBP5.
Tanaka H, Maruyama S, Shoda K, Kawaguchi Y, Higuchi Y, Ozawa T, Nakayama T, Saito R, Izumo W, Takiguchi K, Shiraishi K, Furuya S, Amemiya H, Kawaida H, Ichikawa D
Oncology reports 2025 Dec;54(6)
Oncology reports 2025 Dec;54(6)
LARS1 Promotes Tubular Epithelial Cells Epithelial Mesenchymal Transition in Chronic Kidney Disease by Inhibiting Lipophagy.
Guo R, Chen MN, Lin QH, Qi HM, Wang XQ, Li BY, Wang S, Xu SJ, Zhang Y, Liu W
Inflammation 2025 Dec;48(6):4094-4109
Inflammation 2025 Dec;48(6):4094-4109
Unraveling the miR-144-3p/PUMA pathway: a novel regulator of FDX1-mediated cuproptosis in colorectal cancer.
Jia G, Li J, Jiang M, Liu N, Ding N, Jiang X, Zhang G, Tan X, Kang Y, Zhang L, Wang F, Zhang Y
Cellular oncology (Dordrecht, Netherlands) 2025 Dec;48(6):1693-1710
Cellular oncology (Dordrecht, Netherlands) 2025 Dec;48(6):1693-1710
Taohong Siwu Decoction relieves renal fibrosis: based on network pharmacology and experimental confirmation.
Zhang XQ, Gong Y, Wang YH, Su HW, Tan RZ, Fan JM, Wang L
Renal failure 2025 Dec;47(1):2539948
Renal failure 2025 Dec;47(1):2539948
Identification of biomarkers for chronic renal fibrosis and their relationship with immune infiltration and cell death.
Shi J, Qin X, Sha H, Wang R, Shen H, Chen Y, Chen X
Renal failure 2025 Dec;47(1):2449195
Renal failure 2025 Dec;47(1):2449195
TM4SF1 as a Prognostic Biomarker and Therapeutic Target in Cervical Cancer.
Deng JX, Zhang LY, Ouyang ZQ, Guo T, Shen FJ, Zheng HY
Current medical science 2025 Dec;45(6):1367-1381
Current medical science 2025 Dec;45(6):1367-1381
Mechanistic insights into FUNDC2P4 and HSF1 regulation of EMT in residual hepatocellular carcinoma following insufficient radiofrequency ablation.
Tang N, Yang L, Huang C, Yang L, Yang L, Zhang H, Zeng J
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2025 Dec;42(1):2553210
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2025 Dec;42(1):2553210
TLyp-1-modified exosome-mediated delivery of circRAPGEF5 ASO inhibits lung adenocarcinoma metastasis via regulating the miR-570-3p/SPP1 axis.
Hu T, Zhou C, Chen Y, Fu J, Dai Y, Ling L, Chen Y, Lu Y, He Y, Chen J, Wang Y
Materials today. Bio 2025 Dec;35:102416
Materials today. Bio 2025 Dec;35:102416
CircRAB23 functions as miR-532-3p sponge to promote the malignant proliferation and metastasis of intrahepatic cholangiocarcinoma through HMGA2-EMT axis.
Zhang K, Chen J, Shen S, Zhang H, Xia J, Zhao Y, Yang P, Yan X, Liu C, Ge R, Wang N, Yang X
International journal of biological macromolecules 2025 Dec;332(Pt 2):148685
International journal of biological macromolecules 2025 Dec;332(Pt 2):148685
Cholesterol metabolism in LUAD progression: GJB3 as a key target for cell‑based therapeutic interventions.
Yan Q, Chang W, Wong W, Gong L, Liang D, Yang J, Wang J
Molecular medicine reports 2025 Dec;32(6)
Molecular medicine reports 2025 Dec;32(6)
The Effect of Prenatal Dexamethasone Exposure on Placental Morphology and Function at Different Stages, Doses, and Courses In Mice.
Feng H, Lin Y, Zhao X, Ge C, Zhong W, Zha X, Fang M, Wang H, Zhang M
Reproductive sciences (Thousand Oaks, Calif.) 2025 Dec;32(12):3943-3959
Reproductive sciences (Thousand Oaks, Calif.) 2025 Dec;32(12):3943-3959
GLDC interacts with VPS34 to inhibit tumorigenesis and epithelial-mesenchymal transition in hepatocellular carcinoma.
Song Z, Dong H, Zhang K, Qiao B, Li L, Zhang Z, Fan Z, Li J, Li Y, Liu M, Liu Y, Gu X, Zhang T
Pharmaceutical science advances 2025 Dec;3:100072
Pharmaceutical science advances 2025 Dec;3:100072
CircATP5C1 promotes triple-negative breast cancer progression by binding IGF2BP2 to modulate CSF-1 secretion.
Liu H, Wang H, Gao W, Yuan Y, Tang T, Sang M, Liu F, Geng C
Cancer biology & therapy 2025 Dec;26(1):2479926
Cancer biology & therapy 2025 Dec;26(1):2479926
Upregulation of TTYH3 by lncRNA LUCAT1 through interacting with ALYREF facilitates the metastasis in non-small cell lung cancer.
Fang F, Zhao M, Meng J, He J, Yang C, Wang C, Wang J, Xie S, Jin X, Shi W
Cancer biology & therapy 2025 Dec;26(1):2464966
Cancer biology & therapy 2025 Dec;26(1):2464966
Macrophage extracellular traps impair intestinal barrier function in DSS-induced colitis in mice by inducing intestinal epithelial cell apoptosis.
Zhou Z, Miao X, Shen Y, Wang P, Shi R, Fan H, Yang Y, Guo M, Wu J
Biochemical pharmacology 2025 Dec;242(Pt 3):117406
Biochemical pharmacology 2025 Dec;242(Pt 3):117406
ACOD1/Itaconate regulates trophoblast function through the PI3K/Akt/FOLR1 axis to participate in the pathogenesis of recurrent spontaneous abortion.
Feng T, Wu S, Fang J, Ding J, Shen F, Yang J
Biochemical pharmacology 2025 Dec;242(Pt 3):117405
Biochemical pharmacology 2025 Dec;242(Pt 3):117405
The role and mechanisms of the microRNA-1180-3p/MKNK2/CREB3 signaling axis in tumor progression following insufficient radiofrequency ablation of colorectal cancer liver metastasis.
Gao Y, Zhu J, Xin H, Ni B, Liu Z
Biochemical pharmacology 2025 Dec;242(Pt 3):117216
Biochemical pharmacology 2025 Dec;242(Pt 3):117216
Juglone targets MMP-1 to inhibit gastric cancer progression.
Zhou F, Xie Y, Li X, Peng P
Biochemical pharmacology 2025 Dec;242(Pt 2):117289
Biochemical pharmacology 2025 Dec;242(Pt 2):117289
Single-Cell and Spatial Transcriptomics-Based Research Reveals Association Between M2a Macrophages and Tumor Spread through Air Spaces in Lung Adenocarcinoma.
Ding Y, Zhang H, Wen H, Zhao S, Li J, Liu X, Wang K, Huang Y, Xu M, Sun D
The American journal of pathology 2025 Dec;195(12):2477-2491
The American journal of pathology 2025 Dec;195(12):2477-2491
Acyl-CoA dehydrogenase long chain acts as a tumor-suppressive factor in lung adenocarcinoma progression.
Wei T, Fu G, Zhao J, Cao F, Guo D
Cell adhesion & migration 2025 Dec;19(1):2495676
Cell adhesion & migration 2025 Dec;19(1):2495676
Targeting the ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (ST3Gal1) as a potential therapeutic strategy to overcome anti-VEGF resistance in endometrial cancer.
Liu CH, Yang ST, Chao WT, Lin CH, Lee YC, Lai CR, Hsieh SL, Wang LW, Wang PH
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2025 Dec;171(3):1343-1354
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2025 Dec;171(3):1343-1354
Desulfovibrio vulgaris flagellin exacerbates colorectal cancer through activating LRRC19/TRAF6/TAK1 pathway.
Dong Y, Meng F, Wang J, Wei J, Zhang K, Qin S, Li M, Wang F, Wang B, Liu T, Zhong W, Cao H
Gut microbes 2025 Dec;17(1):2446376
Gut microbes 2025 Dec;17(1):2446376
Novel role of FTO in regulation of gut-brain communication via Desulfovibrio fairfieldensis-produced hydrogen sulfide under arsenic exposure.
Chen R, Chai X, Zhang Y, Zhou T, Xia Y, Jiang X, Lv B, Zhang J, Zhou L, Tian X, Wang R, Mao L, Zhao F, Zhang H, Hu J, Qiu J, Zou Z, Chen C
Gut microbes 2025 Dec;17(1):2438471
Gut microbes 2025 Dec;17(1):2438471
Neutrophil extracellular trap-borne C3-driven endothelial dysfunction in Klebsiella pneumoniae liver abscess.
Wang H, Chen L, Wang C, Chang Z
Virulence 2025 Dec;16(1):2580104
Virulence 2025 Dec;16(1):2580104
Hypoxia-induced secretory autophagy in cancer-associated fibroblasts promotes ECM remodelling through serglycin secretion in oral squamous cell carcinoma.
Zhang Y, Tao C, Yin X, Wang Z, Zhang Y, Yu J, Wang Y, Han W
Clinical and translational medicine 2025 Dec;15(12):e70556
Clinical and translational medicine 2025 Dec;15(12):e70556
Targeting renal tubular epithelial cells via a dual functionalized oligosaccharide self-assembly in the management of acute and chronic kidney diseases.
Xu Y, Gui J, Zhang Y, Nan S, Che Y, Cao X, Fang X, Gong T, Zhang Z, Fu Y
Acta pharmaceutica Sinica. B 2025 Dec;15(12):6607-6625
Acta pharmaceutica Sinica. B 2025 Dec;15(12):6607-6625
Adipose-derived mesenchymal stem cell exosomes protect keratinocytes from high-glucose injury by modulating KEAP1/NRF2/HO-1 axis.
Yuan Y, Song S, Xiao Y, Feng R, Li M, Zhang H, Luo L, Wang K, Wang P, Wei L, Zhang Y, Zhang B, Jiang S, Shen K, Guan H, Hu D
Cellular signalling 2025 Dec;136:112172
Cellular signalling 2025 Dec;136:112172
GPR108 deficiency promotes urate-induced renal interstitial fibrosis.
Xu D, Yang P, Song W, Liao K, Zang D, Zhou Q, Zhou H
Cellular signalling 2025 Dec;136:112129
Cellular signalling 2025 Dec;136:112129
Formononetin, a Key Component of Danggui Buxue Decoction, Inhibits Metastasis of Triple-Negative Breast Cancer by Modulating SNAI2-Driven EMT.
Li K, Zhou T, Wu R, Xiong J
Food science & nutrition 2025 Dec;13(12):e71286
Food science & nutrition 2025 Dec;13(12):e71286
CircLRBA Promotes Epithelial-Mesenchymal Transition, Immune Evasion, Chemoimmunotherapy Resistance and Metastasis Through Stabilizing Twist1.
Wang X, Yang X, Xing L, Chen H, Xie F, Wang B, Shi B, Yang Y, Chen J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(48):e08918
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(48):e08918
Synergistic Promotion of Triple-Negative Breast Cancer Tumorigenesis and Metastasis by Oral Polystyrene Nanoplastics Exposure via Alloprevotella-Derived Glutamate and Platelet Activation.
Zhu L, Xu P, Zhou M, Li K, Tian S, Fan X, Liu J, Ye B, Ding Z, Shen Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e08310
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e08310
Skullcapflavone II Inhibits SLC1A4-Mediated L-Serine Uptake and Promotes Mitochondrial Damage in Gastric Cancer.
Zhao J, Ma YB, Xia RH, Jiang ZC, Zhou Y, Wang YN, Yang MY, Dai JJ, Zhu T, Pan LB, Yuan L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(45):e17225
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(45):e17225
In Vitro Evidence for Oral Soft Tissue Regenerative Effects of a Polynucleotide-Hyaluronan Formulation.
Mladenova I, Song X, Nica C, Sculean A, Asparuhova MB
Clinical and experimental dental research 2025 Dec;11(6):e70253
Clinical and experimental dental research 2025 Dec;11(6):e70253
METTL3-mediated m(6)A modification regulates OSCC progression via the HNRNPA2B1/FOXQ1 axis.
Wang X, Li Y
Scientific reports 2025 Dec 9;16(1):2362
Scientific reports 2025 Dec 9;16(1):2362
Periodic asymmetric field enhances electrofusion of nanoscale lipid systems.
Wu H, Liu WC, Wu X, Li Z, Zhang J, Wang J, Zhu Q, Zhang J, Dong K, Lin R, Hu H, Zeng J, Wu J, Li K, Nan K, Zhang T, Gao J
Nature communications 2025 Dec 9;16(1):10980
Nature communications 2025 Dec 9;16(1):10980
The SREBF2-ACOT7 axis promotes tumor progression and predicts prognosis in diffuse large b-cell lymphoma.
Wang H, Yao X, Wu S, Heng J, Cheng Y, Li L
Scientific reports 2025 Dec 7;15(1):43505
Scientific reports 2025 Dec 7;15(1):43505
Exosome-derived Menin from cancer-associated fibroblasts promotes gastric cancer progression by activating the HSPA6/JNK/JunD pathway and inducing EMT.
Wang SH, Jiang JX, Zheng KT, Zhang SJ, Chen TD, Wang Z
Journal of translational medicine 2025 Dec 6;24(1):274
Journal of translational medicine 2025 Dec 6;24(1):274
PLS3 Is a Prognostic Biomarker and Correlates with Immune Infiltrates in Head and Neck Squamous Cell Carcinoma.
Wang Y, Chen K, Tian G, Hou C, Huang Y, Song F, Zhang M, Hou J
Cancers 2025 Dec 4;17(23)
Cancers 2025 Dec 4;17(23)
KY216-tubulin complex captures VASH2 to inhibit NSCLC metastasis.
He XY, Liu CY, Ding XY, Lin Q, Leng JF, Xiao CM, Zang X, Wang MY, Yin Y, Kong LY, Xia YZ
Nature communications 2025 Dec 4;17(1):191
Nature communications 2025 Dec 4;17(1):191
Bile metabolite palmitic acid augments the migration of gallbladder cancer cells through the ROS/NF-кB signaling pathway.
Da X, Guo Q, Lu Y, Huang J, Mo J, Lu L, Fan M, Zhao X, Guo T, Qi Z, Haoshang, Lu H
Scientific reports 2025 Dec 4;16(1):1262
Scientific reports 2025 Dec 4;16(1):1262
HMGB1-enhanced autophagic degradation of E-cadherin facilitates mesothelial trans-differentiation and postoperative peritoneal adhesion.
Yuan X, Yang S, Qu C, Zhang R, Ren Y, Sun Y, Li E, Li G, Zhang J, Du J, Shen T, Jiang Z, Li X
BMC gastroenterology 2025 Dec 30;26(1):83
BMC gastroenterology 2025 Dec 30;26(1):83
TAGLN: a stiffness-driven prognostic biomarker for metastatic colorectal cancer.
Ye Y, Jia Y, Li W
Cancer cell international 2025 Dec 30;26(1):54
Cancer cell international 2025 Dec 30;26(1):54
Six1 promotes alveolar epithelium senescence in pulmonary fibrosis through regulating Tp53.
Fan Y, Tian Z, Zheng H, Xu R, Li B, Wang S, Huang Z, Wang M, Ding D, Zhao J, Xie J
International immunopharmacology 2025 Dec 3;166:115554
International immunopharmacology 2025 Dec 3;166:115554
EXOSC3 knockdown induces G1/S phase arrest to suppress hepatocellular carcinoma cell proliferation.
Chen YM, Huo YX, Wei WS, Liu YX, Wang SH, Jiang L, Rong-He, Zhang HL, Jiang LH
Scientific reports 2025 Dec 29;15(1):44684
Scientific reports 2025 Dec 29;15(1):44684
Integrating Network Pharmacology, Machine Learning, and Experimental Validation to Elucidate the Mechanism of Cardamonin in Treating Idiopathic Pulmonary Fibrosis.
Zhang W, Guo Y, Wang Q, Wang K, Zhang H, Chang S, Yang A, Liu Z, Sun Y
International journal of molecular sciences 2025 Dec 25;27(1)
International journal of molecular sciences 2025 Dec 25;27(1)
Shikonin inhibits multiple tumor malignant phenotypes and is associated with Hedgehog pathway downregulation in lung adenocarcinoma.
Wang HG, Lu MX, Sheng ML, Lou YB, Xiao YC, Guo A, Yu ZH
Scientific reports 2025 Dec 24;15(1):44516
Scientific reports 2025 Dec 24;15(1):44516
FOXL2 + cancer-associated fibroblasts enhances epithelial ovarian cancer development via TGFβ/Smad signaling.
Zhao L, Nie J, Wang J, Li D, Hao X
BMC cancer 2025 Dec 23;26(1):147
BMC cancer 2025 Dec 23;26(1):147
PAK2 promotes CTC cluster formation by phosphorylating E-cadherin to enhance cell-cell adhesion in breast cancer.
Guo L, Li J, Zhu W, Wang Z, Huang Y, Sun Z, Huang Y, Xu K
Breast cancer research : BCR 2025 Dec 21;28(1):17
Breast cancer research : BCR 2025 Dec 21;28(1):17
[PSMD11 overexpression promotes epithelial-mesenchymal transition in gastric cancer and affects patient prognosis].
Zhou R, Yang J, Song B, Chen X, Wang L, Wang Y, Zuo L, Zhu B
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2025 Dec 20;45(12):2747-2755
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2025 Dec 20;45(12):2747-2755
GPX8 is transcriptionally regulated by KLF16 and promotes osteosarcoma progression.
Dong C, Gao Z, Li X
Journal of translational medicine 2025 Dec 2;23(1):1369
Journal of translational medicine 2025 Dec 2;23(1):1369
A novel super-enhancer-driven lncRNA LINC00973 governs head and neck squamous cell carcinoma progression through EN2.
Wang A, Diao P, Xiao N, Wei Y, Wu Y, Wang Y, Wang X, Yan E, Jiang H, Li J, Cheng J
Cell death & disease 2025 Dec 19;17(1):111
Cell death & disease 2025 Dec 19;17(1):111
Targeting the SMAD3/CISD2 axis suppresses bladder cancer progression by promoting ferroptosis in mesenchymal-like bladder cancer cells.
Sun Y, Wang J, Gu D, Lou H, Sun J, Cui Z, Kang W
Cell death & disease 2025 Dec 18;17(1):101
Cell death & disease 2025 Dec 18;17(1):101
METTL3-mediated m6A modification of TACSTD2 mRNA inhibits papillary thyroid cancer progression by activating the TNF signaling and blocking epithelial-mesenchymal transition.
Man J, Zhang Z, Cui T, Shi T
Scientific reports 2025 Dec 18;16(1):857
Scientific reports 2025 Dec 18;16(1):857
The role of hsa_circ_0000520 in breast cancer progression: insights into the miR-542-3p/TMBIM6 regulatory axis.
Wang F, Sun R, Wang B, Qu G
Cancer gene therapy 2025 Dec 18;
Cancer gene therapy 2025 Dec 18;
S1PR3 Inhibition in alveolar epithelial cells alleviates pulmonary fibrosis by enhancing alveolar barrier function.
Hao M, Tang G, Zhou E, Fu R, Wang M, Jiang H, Chen X, Bai L, Lv X, Jin J
Respiratory research 2025 Dec 12;27(1):15
Respiratory research 2025 Dec 12;27(1):15
Lung adenocarcinoma cells respond differently to mechanical stress in 3D versus 2D environments.
Kitamura N, Iwatake M, Mizoguchi S, Ibrahim Wani S, Kobayashi K, Hasnain M, Nguyen VD, Yokoyama R, Kitade N, Ojima T, Shimoyama K, Koba N, Hatta H, Raredon MSB, Hirabayashi K, Morinaga Y, Tsuchiya T
Communications biology 2025 Dec 11;8(1):1819
Communications biology 2025 Dec 11;8(1):1819
Remimazolam attenuates traumatic brain injury-induced acute lung injury by suppressing pulmonary epithelial pyroptosis.
Sun C, Zhang Y, Wang J, Wang B, Gu A, Wang Y, Gu C
Journal of neuroinflammation 2025 Dec 11;23(1):16
Journal of neuroinflammation 2025 Dec 11;23(1):16
Haematococcus pluvialis ameliorates renal fibrosis by restoring mitophagy via PINK1-Parkin-p62-LC3 signaling.
Wu Y, Chen C, Xie J, Chang X, Zhang Y, Zheng Y, Yuan Y, Hu W, Xie X
NPJ science of food 2025 Dec 11;10(1):9
NPJ science of food 2025 Dec 11;10(1):9
CD36-mediated fatty acid metabolic reprogramming activates synovial fibroblasts and promotes rheumatoid arthritis progression.
Hao J, Zheng J, Liu C, Lu J, Tan M, Li J, Mao J, Yu Y, Wang H, Zhang Y, Shen H
International immunopharmacology 2025 Dec 10;167:115594
International immunopharmacology 2025 Dec 10;167:115594
CircRNA hsa_ circ_0009022 inhibits colorectal cancer progression by sponging miR-576-5p and complexing with FMRP.
Guo J, Wang Y, Yang Y, Feng S, Cai J, Fan S, Wang J, Li N, Qian X, Zhu H
Tissue & cell 2025 Aug;95:102924
Tissue & cell 2025 Aug;95:102924
ZEB1 Contributes to Drug Resistance Through Canonical Wnt Signaling in Lung Cancer.
Shi H, Wang M, Zhao Q, Xu Y
IUBMB life 2025 Aug;77(8):e70053
IUBMB life 2025 Aug;77(8):e70053
The role of formin-like protein 1 in pancreatic cancer and its specific effects on immunity.
Liu J, Ding J, Chen L, Shao S, Mei J, Yang X
The Journal of international medical research 2025 Aug;53(8):3000605251365844
The Journal of international medical research 2025 Aug;53(8):3000605251365844
METTL1-mediated m7G modification promotes colorectal cancer metastasis via stabilization of ICAM-1.
Cai S, Mi S, Chen J, Shao L, Yang X, Xue M
Molecular and cellular biochemistry 2025 Aug;480(8):4769-4780
Molecular and cellular biochemistry 2025 Aug;480(8):4769-4780
P5CS deacetylation mediated by SIRT2 facilitates tumor growth by enhancing mitochondrial respiration in hepatocellular carcinoma.
Geng X, Li M, Zhang L, Cai Y, Chen X, Mu X, Wang J, Liu B
Oncogene 2025 Aug;44(31):2746-2761
Oncogene 2025 Aug;44(31):2746-2761
Application of PVA hydrogel loaded with luteolin nanoparticles in anti EMT treatment after GBM.
Zhou L, Zhao Q, Gu L, Tian R, Li Y, Xiong X
Materials today. Bio 2025 Aug;33:101956
Materials today. Bio 2025 Aug;33:101956
Thermosensitive hydrogel composite with si-Cx43 nanoparticles and anti-VEGF agent for synergistic treatment of diabetic retinopathy.
Wen L, Gan M, Xiong S, Dai L, Chen W, Shi W
Materials today. Bio 2025 Aug;33:101917
Materials today. Bio 2025 Aug;33:101917
circGAPVD1 inhibits the progression of gastric cancer through miR-4424/STK4 axis and encoding GAPVD1-137aa protein.
Zhu L, Yao Z, Liu Y, Shao S, Zhou W, Ding J, Mao B, Shao C, Cui F
International journal of biological macromolecules 2025 Aug;319(Pt 3):145408
International journal of biological macromolecules 2025 Aug;319(Pt 3):145408
Lactoferrin prevents heat stroke-induced intestinal barrier damage by reducing ferroptosis via regulating MAPK signaling pathway: In vitro and in vivo studies.
Li L, Wang Y, Pei Y, Chen J, Zhou J, Gong Y, You J, Cao Y, Chen J, Cai Y, Chang W, Ma J, Ma W, Li X, Song Q, Xu S
International journal of biological macromolecules 2025 Aug;319(Pt 2):145454
International journal of biological macromolecules 2025 Aug;319(Pt 2):145454
Dysregulated RNA m6A Methylation Contributes to the Metastasis of Gallbladder Cancer Through miR-146a-5p.
Liu Y, He R, Wang W, Xia Q, Zhang D, Pan S, Wang M, Zhang Q, Xu S, Gong J, Qin R
Journal of cellular and molecular medicine 2025 Aug;29(15):e70764
Journal of cellular and molecular medicine 2025 Aug;29(15):e70764
p66shc exacerbates the progression of obstructive nephropathy through apoptosis, mitochondrial damage, and EMT.
Gao X, Fan X, Yu X, Wang R, Zhang B, Li Y, Liu X, Yang Y
Journal of pediatric urology 2025 Aug;21(4):834-843
Journal of pediatric urology 2025 Aug;21(4):834-843
m6A-mediated regulation of ECA39 promotes renal fibrosis in chronic kidney disease by enhancing glycolysis and epithelial-mesenchymal transition.
Tong Z, Zhao H, Cui C, Hong M, Ma Y, Sui L, Wang J, Yuan Q, Sun L
Biochimica et biophysica acta. Molecular cell research 2025 Aug;1872(6):119981
Biochimica et biophysica acta. Molecular cell research 2025 Aug;1872(6):119981
Gestational TCBPA exposure impairs placental function and fetal Development: Mechanisms of syncytialization disruption and fetal growth restriction.
Wang S, Wang S, Zhang X, Lyu Z, Lu C, Long Z, Chen X, Zhuang T, Xu X
Placenta 2025 Aug;168:88-97
Placenta 2025 Aug;168:88-97
Revealing a new target: Celastrol alleviates pulmonary fibrosis by inhibiting PCAF.
Wang L, Lin F, Liu J, Jia Z, Zhu M, Liu Y, Li Y, Yang L
Bioorganic chemistry 2025 Aug;163:108722
Bioorganic chemistry 2025 Aug;163:108722
Pyrrolidinium Fullerenes as YTHDF1 Inhibitors for Targeted Tumor Therapy.
Wang X, Zhang W, Huo J, Wang Z, Liu Y, Yang L, Zhang S, Chen S, Xu Y, Qi H, Sun J, Pan Y, Lu Y, Li B, Wang Y, Liu M, Li J, Li S, Zhao C, Li Y, Yu F, Wang Z, Guo Q, Li J, Wang C
Advanced healthcare materials 2025 Aug;14(22):e2501360
Advanced healthcare materials 2025 Aug;14(22):e2501360
F-box only protein 10 protects against kidney tubulointerstitial fibrosis by inhibiting ACSL4-mediated lipid peroxidation and ferroptosis.
Hu J, Ma F, Chen X, Lu X, Lu Y, Jiang Y
Cellular signalling 2025 Aug;132:111841
Cellular signalling 2025 Aug;132:111841
HnRNPR promotes non-small cell lung cancer progression by protecting XB130 mRNA from XRN1- and DIS3L2-mediated degradation.
Wang QR, Liu LL, Gou XJ, Liu Y, Zhao Y, Zhang T, Jiang YH, Zhou JJ, Li JL, Zhang J, Xie Y
Cellular signalling 2025 Aug;132:111816
Cellular signalling 2025 Aug;132:111816
Circ847 upregulation via CAFs suppresses salivary adenoid cystic carcinoma progression through VIM-EMT.
Liang Y, Zhou Y, Xu T, Wang Y, Xu X, Chen R, Jiang Q, Lu N, Zhao L, Huang Z, Huang Z
Cellular signalling 2025 Aug;132:111806
Cellular signalling 2025 Aug;132:111806
GATA2 promotes cervical cancer progression under the transcriptional activation of TRIP4.
Wang R, Zhang F, Li J, Yang D, Zhao H, Yuan J, Jia Y, Yu W, Guo W, Zou L, Zou K
Cellular signalling 2025 Aug;132:111778
Cellular signalling 2025 Aug;132:111778
Gut microbiota promote the propagation of pathologic α-syn from gut to brain in a gut-originated mouse model of Parkinson's disease.
Wu J, Li CS, Huang WY, Zhou SY, Zhao LP, Li T, Li MA, Zhang MX, Qiao CM, Zhao WJ, Cui C, Shen YQ
Brain, behavior, and immunity 2025 Aug;128:152-169
Brain, behavior, and immunity 2025 Aug;128:152-169
Nanoparticle conjugation of ginsenoside Rh2 enhanced antitumor efficacy on hepatocellular carcinoma.
Sun F, Liu J, Gao S, Zhang M, Sun X, Tian Y, Wang S
Scientific reports 2025 Aug 8;15(1):29111
Scientific reports 2025 Aug 8;15(1):29111
ZC3H13 mediates N6-methyladenosine modification of SNTB1 to promote epithelial-mesenchymal transition in gastric cancer.
Xie X, Zhao Y, Liu J, Li H, Zhu X, Liu Y, Sang Y, Xu K, Du F, Ren H, Cui X, Cai B, Chen H, Wu N, Hou G, Jing C, Chong W, Li L, Shang L
Cell death & disease 2025 Aug 7;16(1):596
Cell death & disease 2025 Aug 7;16(1):596
Neurotensin receptor1 signaling promotes progression of epithelial-mesenchymal transition in mice with chronic rhinosinusitis through Wnt3a/β-catenin pathway.
Wu Y, Zhu X, Gu H, Fu F, Guo Q, Liu K, Yang M, Zhang T, Wang X
Journal of molecular histology 2025 Aug 6;56(4):253
Journal of molecular histology 2025 Aug 6;56(4):253
Emodin-Enhanced hUC-MSC extracellular vesicles alleviate acute pancreatitis by targeting inflammation and pyroptosis.
Liu X, Huang X, Huang X, Liu S, Hu J, Lin J
Stem cell research & therapy 2025 Aug 6;16(1):434
Stem cell research & therapy 2025 Aug 6;16(1):434
G-protein coupled receptor 183 (GPR183) inhibits visceral metastasis of non-small cell lung cancer.
Cheng L, Li S, Cui Z, Sun X, Gong M, Chen Y, Meng L, Liao Y
Clinical & experimental metastasis 2025 Aug 4;42(5):44
Clinical & experimental metastasis 2025 Aug 4;42(5):44
Promotion of the invasion and metastasis of breast cancer by B7-H3 through CCR5High tumor-associated macrophages.
Dai T, Xu Z, Li Y, Wu M, Qiu Y, Chao Z, Jiang R, Chen Y, Lu L
Cancer cell international 2025 Aug 4;25(1):293
Cancer cell international 2025 Aug 4;25(1):293
Role of the transcription factor SOX8 in hepatocellular carcinoma development and lymph node metastasis.
Teng X, Li TM, Peng K, Li YH, Zhang HJ, Ge B, Xie HX, Yang KJ, Qin CJ, Liao XW, Zhu GZ, Zhou X, Peng T
Translational cancer research 2025 Aug 31;14(8):4882-4905
Translational cancer research 2025 Aug 31;14(8):4882-4905
Beyond energy metabolism: ketogenic diet and β-hydroxybutyrate protect against intestinal ischemia-reperfusion injury through anti-inflammatory and barrier-preserving effects.
Wang FX, Wei N, Dai SY, Zhong X, Mu G, Fan X, Chen SR, Chen Y, Zhou J
Biochemical and biophysical research communications 2025 Aug 30;776:152227
Biochemical and biophysical research communications 2025 Aug 30;776:152227
DDX18 promotes growth and metastasis of hepatocellular carcinoma via activating EMT and MAPK signaling.
Xu X, Yu X, Zhang N, Wang F, Chen Z
Journal of gastrointestinal oncology 2025 Aug 30;16(4):1622-1634
Journal of gastrointestinal oncology 2025 Aug 30;16(4):1622-1634
Exosomal Biglycan promotes gastric cancer progression via M2 polarization and CXCL10-mediated JAK/STAT1 activation.
Li W, Wei H, Liu J, Zhao Z, Wang F, Qiao L, Yin S, Zhang C, Huo M
Cancer letters 2025 Aug 28;626:217758
Cancer letters 2025 Aug 28;626:217758
Inhibition of macrophage extracellular traps by Metrnl/IL-41 suppresses airway remodeling in asthma.
Feng K, Cen J, He C, Zou X, Yang H, Lin Y, Li H, Zhang T
Biochemical pharmacology 2025 Aug 28;242(Pt 1):117288
Biochemical pharmacology 2025 Aug 28;242(Pt 1):117288
Protein lactylation of citrate synthase promotes the AKI-CKD transition by activating the NLRP3 inflammasome.
Yu F, Meng Y, Wang X, Chen J, He J, Yi X, He Y, Chen K
Cell reports 2025 Aug 26;44(8):116084
Cell reports 2025 Aug 26;44(8):116084
Paris saponin VII restrains PD-L1 mediated immune evasion through the AKT1 and STAT3 signaling pathways.
Wang Y, Li Y, Zhang Y, Li Y, Zhao L, Tong L, Zhu X, Wang J, Dong Y
Chemico-biological interactions 2025 Aug 25;417:111562
Chemico-biological interactions 2025 Aug 25;417:111562
Association of lipoprotein(a) and LPA gene with calcific aortic valve disease.
Yu X, Fu Z, Yu M, Shi Y
European journal of medical research 2025 Aug 22;30(1):787
European journal of medical research 2025 Aug 22;30(1):787
CircZFR/YTHDF3 axis drives lymph node metastasis in cervical cancer via FASN translation.
Zhou M, Gao Y, Zhang Y, He L, Gao B, Zhang Y, Claret FX, Calin GA, Wang D
Molecular cancer 2025 Aug 21;24(1):218
Molecular cancer 2025 Aug 21;24(1):218
Osteopontin derived from hypoxia-induced M2 macrophages promotes osteosarcoma progression through modulation of EGR3/ISG15 signaling and RIG-I expression.
Xing C, Hu W, Zhao L
Journal of translational medicine 2025 Aug 21;23(1):950
Journal of translational medicine 2025 Aug 21;23(1):950
Supersulfides regulate cell migration in human skin keratinocytes.
Kunihiro K, Sano K
Cell structure and function 2025 Aug 20;50(2):169-182
Cell structure and function 2025 Aug 20;50(2):169-182
METTL3 promotes peritoneal metastasis of colorectal cancer through regulating m6A modification of NRXN3 mRNA.
Lan TH, Li W, Wang X, Geng YJ, Pang B, Kang LF, Li DY, Pang LY, Zhang XX, Zhang CQ, Wang GQ, Li ZX, Zhou CM, Jiang X, Zhao ZR
iScience 2025 Aug 15;28(8):113165
iScience 2025 Aug 15;28(8):113165
Suppressive effects of Momordica charantia MAP30 on the senescence, proliferation and migration of bladder cancer cells mediated by CENPA.
Lu K, Chao L, Wang J, Wang X, Cai L, Zhang J, Zhang S
Scientific reports 2025 Aug 13;15(1):29679
Scientific reports 2025 Aug 13;15(1):29679
miRNA-204-5p acts as a tumor suppressor in gastric cancer by inhibiting cell migration, invasion, and glycolysis via the RAB22A/PI3K/AKT axis.
Pan W, Tan Y, Chen X, Zeng L, Lv Y, Yang J
Scientific reports 2025 Aug 12;15(1):29536
Scientific reports 2025 Aug 12;15(1):29536
Glia maturation factor-β in hepatocytes enhances liver regeneration and mitigates steatosis and ballooning in zebrafish.
Li HY, Zeng WL, Ye YW, Chen X, Zhang MM, Chen YS, Liu CT, Zhong ZQ, Li J, Wang Y
American journal of physiology. Gastrointestinal and liver physiology 2025 Aug 1;329(2):G291-G306
American journal of physiology. Gastrointestinal and liver physiology 2025 Aug 1;329(2):G291-G306
Akkermansia muciniphila Protects Against Trinitrobenzene Sulfonic Acid Induced Colitis by Inhibiting IL6/STAT3 Pathway.
Jiang M, Jia Y, Ma C, Zeng Z, Wu Y, Gan H, Zhang H
Inflammatory bowel diseases 2025 Aug 1;31(8):2217-2230
Inflammatory bowel diseases 2025 Aug 1;31(8):2217-2230
TGF-β1 induces ROS to activate ferroptosis via the ERK1/2-WISP1 pathway to promote the progression of renal tubular epithelial cell fibrosis.
Zhou Y, Luan F, Feng X, Yu M, Li L, Guo X, Yin X
Cytotechnology 2025 Apr;77(2):61
Cytotechnology 2025 Apr;77(2):61
The Long Noncoding RNA Gall Bladder Cancer-Associated Suppressor of Pyruvate Carboxylase Inhibits the Proliferation, Migration, and Invasion of Colorectal Cancer Cells and Induces Their Apoptosis.
Xie T, Guo J, Wang W
Biochemical genetics 2025 Apr;63(2):1719-1733
Biochemical genetics 2025 Apr;63(2):1719-1733
Tumor-stroma proportion is associated with increased M2 macrophage abundance and predicts the resistance to immune checkpoint blockade in breast cancer.
Liu Y, Xue N, Liu Y, Mei J, Cai Y, Wang Z, Lin H, Wan M, Zhou J, Xia T, Zhu Y, Wang S
Translational oncology 2025 Apr;54:102343
Translational oncology 2025 Apr;54:102343
Hypoxic Cancer Cells-Derived Exosomes Strengthen the Development of Cancer Stem Cell-Like Properties Through Delivering LINC00665 in Thyroid Cancer Cells.
Zhou M, Peng C, Zhang Q, Tong Y
Cell biology international 2025 Apr;49(4):384-396
Cell biology international 2025 Apr;49(4):384-396
PLEK2 promotes migration and invasion in pancreatic ductal adenocarcinoma by MMP1 through IL-17 pathway.
Cheng K, Chen Q, Chen Z, Cai Y, Cai H, Wu S, Gao P, Cai Y, Wu Z, Zhou J, Peng B, Wang X
Molecular and cellular biochemistry 2025 Apr;480(4):2401-2412
Molecular and cellular biochemistry 2025 Apr;480(4):2401-2412
Low molecular weight heparins promote migration and invasion of trophoblast cells through regulating the PI3K/AKT signaling pathway.
Zhou Q, Zhao Y, Fu X
Naunyn-Schmiedeberg's archives of pharmacology 2025 Apr;398(4):4645-4656
Naunyn-Schmiedeberg's archives of pharmacology 2025 Apr;398(4):4645-4656
Cinobufacini Inhibits Survival and Metastasis of Hepatocellular Carcinoma via c-Met Signaling Pathway.
Ma YN, Jiang XM, Hu XQ, Wang L, Gao JJ, Liu H, Qi FH, Song PP, Tang W
Chinese journal of integrative medicine 2025 Apr;31(4):311-325
Chinese journal of integrative medicine 2025 Apr;31(4):311-325
Constructing a 3D co-culture in vitro synovial tissue model for rheumatoid arthritis research.
Wang X, He J, Zhang Q, He J, Wang Q
Materials today. Bio 2025 Apr;31:101492
Materials today. Bio 2025 Apr;31:101492
HDAC3 and Snail2 complex promotes melanoma metastasis by epigenetic repression of IGFBP3.
Wu N, Sun Q, Yang L, Sun H, Zhou Z, Hu Q, Li C, Wang D, Zhang L, Hu Y, Cong X
International journal of biological macromolecules 2025 Apr;300:140310
International journal of biological macromolecules 2025 Apr;300:140310
Pinocembrin alleviates renal ischemia-reperfusion injury/unilateral ureteral obstruction (UUO)-generated renal fibrosis by targeting the CYP1B1/ROS/MAPK axis.
Zhang BH, Chen H, Yang R, Jiang Z, Huang S, Chen Z, Liu C, Wang L, Liu XH
The FEBS journal 2025 Apr;292(8):2119-2144
The FEBS journal 2025 Apr;292(8):2119-2144
FOXA2 Loss in TGF-β1-Induced EMT Suppresses Bisecting-GlcNAc N-Glycan Synthesis in Lung Adenocarcinoma.
Ge W, Wen S, Zhou X, Chen Y, Zeng D, Jiang J, Yang S
Proteomics 2025 Apr;25(8):e202400216
Proteomics 2025 Apr;25(8):e202400216
Design, Synthesis, and Biological Evaluation of Naphthalimide-Polyamine Conjugate as a Potential Anti-Colorectal Cancer Agent.
Dai F, Cao Y, Zhu C, Li Y, Ma X, Wang S, Liu H, Xie X, Gao L, Wang Y, Wang C
Chemistry & biodiversity 2025 Apr;22(4):e202401873
Chemistry & biodiversity 2025 Apr;22(4):e202401873
Design, synthesis and antitumor activity evaluation of novel modified 18β-glycyrrhetinate derivatives as PPARγ agonists.
Lin H, Cui S, Xu X, Chen Q, Ge J, Ai D, Zhu J, Tao Y, Wang L, Ruan L, Ge W
Bioorganic chemistry 2025 Apr;157:108307
Bioorganic chemistry 2025 Apr;157:108307
Bioinformatics Combined With Biological Experiments to Identify the Pathogenetic Link of Type 2 Diabetes for Breast Cancer.
Bao X, Zeng Z, Tang W, Li D, Fan X, Chen K, Wang Y, Ai W, Yang Q, Liu S, Chen T
Cancer medicine 2025 Apr;14(7):e70759
Cancer medicine 2025 Apr;14(7):e70759
Isoforskolin, adenylate cyclase agonist, inhibits endothelial-to-mesenchymal transition in atherosclerosis.
Ma Y, Shi Y, Lun J, Wang M, Zhang C, Li X, Yi Q, Cao X, Hu Z, Yang W, Cai H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156520
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Apr;139:156520
Cannabidiol Enhances the Anticancer Activity of Etoposide on Prostate Cancer Cells.
Erzurumlu Y, Catakli D
Cannabis and cannabinoid research 2025 Apr;10(2):258-276
Cannabis and cannabinoid research 2025 Apr;10(2):258-276
Escin Ia ameliorates DSS-induced chronic colitis in mice by inhibiting inflammation and oxidative stress via the LOXL2/MMP-9 pathway.
Yan J, Xu X, Zhu Y, Wang Y, Duan X
Journal of ethnopharmacology 2025 Apr 9;345:119623
Journal of ethnopharmacology 2025 Apr 9;345:119623
ELK4 induced upregulation of HOMER3 promotes the proliferation and metastasis in glioma via Wnt/β-catenin/EMT signaling pathway.
Wang F, Zhou H, Tian Y, Wang X, Huang Y, Tu Y, Li L, Zhen H
Biology direct 2025 Apr 9;20(1):48
Biology direct 2025 Apr 9;20(1):48
Development and Validation of a Prognostic Model for Lung Adenocarcinoma Based on CAF-Related Genes: Unveiling the Role of COX6A1 in Cancer Progression and CAF Infiltration.
Zhu X, Li B, Qin L, Liang T, Hu W, Li J, Wang J
International journal of molecular sciences 2025 Apr 8;26(8)
International journal of molecular sciences 2025 Apr 8;26(8)
Micro-proteomics reveals distinct protein profiles and SPARC/FGF2/CDH1 regulation of human Sertoli cells between Sertoli cell-only syndrome and normal men.
Du L, Cui Y, Chen W, Li C, He Z
Cellular and molecular life sciences : CMLS 2025 Apr 7;82(1):146
Cellular and molecular life sciences : CMLS 2025 Apr 7;82(1):146
Investigation of c-Fos/c-Jun Signaling Pathways in Periostracum Cicadae's Inhibition of EMT in Gastric Tissue.
Liang H, Jin X, He T, Zhou X, Liu Z, Gao W
Pharmaceuticals (Basel, Switzerland) 2025 Apr 7;18(4)
Pharmaceuticals (Basel, Switzerland) 2025 Apr 7;18(4)
Targeting alveolar epithelial cells with lipid micelle-encapsulated necroptosis inhibitors to alleviate acute lung injury.
Kang ZY, Xuan NX, Zhou QC, Huang QY, Yu MJ, Zhang GS, Cui W, Zhang ZC, Du Y, Tian BP
Communications biology 2025 Apr 6;8(1):573
Communications biology 2025 Apr 6;8(1):573
Cancer-associated fibroblasts secrete CSF3 to promote TNBC progression via enhancing PGM2L1-dependent glycolysis reprogramming.
Qin W, Chen B, Li X, Zhao W, Wang L, Zhang N, Wang X, Luo D, Liang Y, Li Y, Chen X, Chen T, Yang Q
Cell death & disease 2025 Apr 4;16(1):249
Cell death & disease 2025 Apr 4;16(1):249
A comprehensive analysis of deubiquitinase USP20 on prognosis and immunity in pan-cancer.
Wang T, Bai Y, Dong Y, Qin J, Zhou X, Wang A, Liu D, Li X, Ma Z, Hu Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 30;39(8):e70499
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 30;39(8):e70499
Natural Killer Cell Activation Signature Identifies Cyclin B1/CDK1 as a Druggable Target to Overcome Natural Killer Cell Dysfunction and Tumor Invasiveness in Melanoma.
Chen L, Liao W, Huang J, Ding Q, Wu J, Zhang Q, Ding Y, Li D, Li J, Wen X, Zhang X
Pharmaceuticals (Basel, Switzerland) 2025 Apr 30;18(5)
Pharmaceuticals (Basel, Switzerland) 2025 Apr 30;18(5)
The highly expressed GOLPH3 in colorectal cancer cells activates smoothened to drive glycolysis and promote cancer cell growth and radiotherapy resistance.
Zhu K, Fan J, Cai H, Zhou C, Gong Z, Li Z, Yu J
Journal of gastrointestinal oncology 2025 Apr 30;16(2):415-434
Journal of gastrointestinal oncology 2025 Apr 30;16(2):415-434
Dasatinib demonstrates efficacy in organoid derived paclitaxel-resistant Trp53/Cdh1-deficient mouse gastric adenocarcinoma with peritoneal metastasis.
Liu W, Li L, Guo L, Li H, Tang Z, Wang X, Huang L, Sun Y
Cell regeneration (London, England) 2025 Apr 29;14(1):16
Cell regeneration (London, England) 2025 Apr 29;14(1):16
KIF2C promotes oral squamous cell carcinoma progression via PLK1 upregulation: implications for biomarker development and therapeutic targeting.
Wang C, Su Y, Shi J, Feng G
Journal of molecular histology 2025 Apr 28;56(3):146
Journal of molecular histology 2025 Apr 28;56(3):146
HNF4α-Mediated LINC02560 Promotes Papillary Thyroid Carcinoma Progression by Targeting the miR-505-5p/PDE4C Axis.
Su Y, Xu B, Gao C, Pei W, Ma M, Zhang W, Hu T, Zhang F, Zhang S
Biomolecules 2025 Apr 28;15(5)
Biomolecules 2025 Apr 28;15(5)
PYK2 promotes cell proliferation and epithelial-mesenchymal transition in endometriosis by phosphorylating Snail1.
Liu L, Liu L, Yue C, Du S, Liu J, Yu Z
Molecular medicine (Cambridge, Mass.) 2025 Apr 27;31(1):155
Molecular medicine (Cambridge, Mass.) 2025 Apr 27;31(1):155
Cornua cervi degelatinatum inhibits breast cancer stem-like cell properties and metastasis via miR-148a-3p-mediated TGF-β/Smad2 pathway.
Ma Y, Song B, Peng J, Wei F, Hao Y, Wen Y, Lv H, Shi X, Wang Y, Peng T
Journal of ethnopharmacology 2025 Apr 25;346:119709
Journal of ethnopharmacology 2025 Apr 25;346:119709
Development of Novel PRMT7 Inhibitors for the Treatment of Prostate Cancer.
Li J, Sun C, Zhang Y, Ding J, Yao P, Shen H, Shi Z, Wang W, Zhu Y, Kuang W, Tavus A, Wang L, Yuan K, Wang X, Yang P
Journal of medicinal chemistry 2025 Apr 24;68(8):8244-8268
Journal of medicinal chemistry 2025 Apr 24;68(8):8244-8268
Mechanism of Astragalus Polysaccharide in Alleviating Bovine Mammary Fibrosis Through ROS/NLRP3 Inhibition and EMT Regulation.
Zhang J, Liu K, Yang T, Duan H, Xiao L, Zhang Q, Zhang Y, Dong W, Zhao X
Antioxidants (Basel, Switzerland) 2025 Apr 23;14(5)
Antioxidants (Basel, Switzerland) 2025 Apr 23;14(5)
THBS2-producing matrix CAFs promote colorectal cancer progression and link to poor prognosis via the CD47-MAPK axis.
Liu Z, Ba Y, Shan D, Zhou X, Zuo A, Zhang Y, Xu H, Liu S, Liu B, Zhao Y, Weng S, Wang R, Deng J, Luo P, Cheng Q, Hu X, Yang S, Wang F, Han X
Cell reports 2025 Apr 22;44(4):115555
Cell reports 2025 Apr 22;44(4):115555
CD147 regulates the Rap1 signaling pathway to promote proliferation, migration, and invasion, and inhibit apoptosis in colorectal cancer cells.
Xiaoxia F, Rui L, Meiru C, Lu Y, Ying J
Scientific reports 2025 Apr 20;15(1):13647
Scientific reports 2025 Apr 20;15(1):13647
HPV11E6/E7 induces nasal epithelial hyperplasia through JAK2/STAT3 signaling pathway.
Zhang Y, Tian K, Zheng L, Zhu G, Zhao R, Zhou E, Xue X, Huang S, Chen X, Hu B, Yao W
European journal of medical research 2025 Apr 2;30(1):224
European journal of medical research 2025 Apr 2;30(1):224
DCC-2036 inhibits osteosarcoma via targeting HCK and the PI3K/AKT-mTORC1 axis to promote autophagy.
He J, Yin L, Yuan Q, Su X, Shen Y, Deng Z
World journal of surgical oncology 2025 Apr 2;23(1):115
World journal of surgical oncology 2025 Apr 2;23(1):115
P4HA1 is highly expressed in gastric cancer and promotes proliferation and metastasis of gastric cancer cells.
Gao P, Tian H, Ge K, Wang F, Zhao Y, Sun J, Zhang Q
Discover oncology 2025 Apr 19;16(1):575
Discover oncology 2025 Apr 19;16(1):575
PRC1 as an independent adverse prognostic factor in Wilms tumor via integrated bioinformatics and experimental validation.
Wang Y, Gao H, Li X, Li D, Huang F, Sun Y, Liu X, Yang J, Sun F
Scientific reports 2025 Apr 17;15(1):13282
Scientific reports 2025 Apr 17;15(1):13282
PPM1G dephosphorylates α-catenin to maintain the integrity of adherens junctions and regulates apoptosis in Sertoli cells.
Li X, Liu Q, Wang L, Bu T, Yang X, Gao S, Yun D, Sun F
Molecular and cellular endocrinology 2025 Apr 15;600:112493
Molecular and cellular endocrinology 2025 Apr 15;600:112493
STEAP4 facilitates growth, migration, and invasion of prostate carcinoma through upregulation of NOTCH4.
Fan S, Xia Z, Liu W, Zhu Y, Liu X, Gu P, Cui Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 15;39(7):e70508
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Apr 15;39(7):e70508
VRK1 promotes epithelial-mesenchymal transition in hepatocellular carcinoma mediated by SNAI1 via phosphorylating CHD1L.
Li J, Song Z, Dong X, Li L, Gu X, Zhang K, Zhang Z, Li Y, Fan Z, Dong H, Liu Y, Liu M, Zhang H, Liu W, Zhang T
Cell death & disease 2025 Apr 15;16(1):302
Cell death & disease 2025 Apr 15;16(1):302
The LysoPS/GPR174 axis drives metastatic progression in esophageal squamous cell carcinoma through cAMP-PKA-CREB signaling activation.
Xiao R, Xu P, Li X, Shen F, Tao S, Zhu X, Cai Y, Feng Z, Liu Z, Xiao H, Ding F, Zhu M
Journal of translational medicine 2025 Apr 14;23(1):438
Journal of translational medicine 2025 Apr 14;23(1):438
CDC25A inhibition sensitizes melanoma cells to doxorubicin and NK cell therapy.
Gao X, Liu F, Zhang B, Ren T, Zheng Y, Niu Z, Ren H, Liu C, Jiang C, Wang C, Huang H, Ma L, Sun Q
Cell death & disease 2025 Apr 11;16(1):276
Cell death & disease 2025 Apr 11;16(1):276
Oroxylin A may promote cell apoptosis and inhibit epithelial-mesenchymal transition in endometrial cancer, associated with the ERβ/PI3K/AKT pathway.
Fan X, Wu L, Cheng T, Lv W, Tian J, Tao J, Tu S, Tan F, Wang Y
Scientific reports 2025 Apr 10;15(1):12225
Scientific reports 2025 Apr 10;15(1):12225
YTHDF3 drives tumor growth and metastasis by recruiting eIF4B to promote Notch2 translation in breast cancer.
Chen H, Lin L, Qiao Z, Pei Y, Gao Y, Lou K, Yang L, Li C, He Y, Bai J, Zhang G
Cancer letters 2025 Apr 1;614:217534
Cancer letters 2025 Apr 1;614:217534
Bisphenol A-induced cancer-associated adipocytes promotes breast carcinogenesis via CXCL12/AKT signaling.
Dong Z, He L, Wu J, Xie C, Geng S, Wu J, Zhong C, Li X
Molecular and cellular endocrinology 2025 Apr 1;599:112473
Molecular and cellular endocrinology 2025 Apr 1;599:112473
Lack of ALCAT1 enhances the protective effects of aerobic exercise on kidney in HFpEF mice.
Zhang L, Feng L, Zhao Y, Geng Y, Liu R, Ma Y, Bo W, Xi Y, Tian Z
Life sciences 2025 Apr 1;366-367:123500
Life sciences 2025 Apr 1;366-367:123500
A Hybrid Manganese Nanoparticle Simultaneously Eliminates Cancer Stem Cells and Activates STING Pathway to Potentiate Cancer Immunotherapy.
Wu Y, Diao P, Peng Y, Yang Y, Wang Y, Lv P, Li J, Wang D, Cai T, Cheng J
ACS nano 2025 Apr 1;19(12):12237-12252
ACS nano 2025 Apr 1;19(12):12237-12252
Endoglin promotes cell migration and invasion in endometriosis by regulating EMT.
Chen X, Wang J, Tu F, Yang Q, Wang D, Zhu Q
Ginekologia polska 2024;95(9):661-667
Ginekologia polska 2024;95(9):661-667
Single-Cell Spatial-Temporal Analysis of ZNF451 in Mediating Drug Resistance and CD8(+) T Cell Dysfunction.
Tang N, Deng W, Wu Y, Deng Z, Wu X, Xiong J, Zhao Q
Research (Washington, D.C.) 2024;7:0530
Research (Washington, D.C.) 2024;7:0530
Long non-coding RNA HOTAIR promotes tumourigenesis by affecting proliferation, invasion, migration, and apoptosis of liver cancer cells.
Zheng X, Cui R, Jiao Y, Chu D, Wang B, Li N
Folia histochemica et cytobiologica 2024;62(4):165-179
Folia histochemica et cytobiologica 2024;62(4):165-179
Inhibition of IGF2BP1 attenuates the progression of endometriosis through PTBP1.
Su Y, Tian W, Cheng L, Yin L, He X, Wei X
Folia histochemica et cytobiologica 2024;62(1):25-36
Folia histochemica et cytobiologica 2024;62(1):25-36
Inhibition of anlotinib-induced autophagy attenuates invasion and migration by regulating epithelial-mesenchymal transition and cytoskeletal rearrangement through ATG5 in human osteosarcoma cells.
Zheng B, Sun X, Zhang L, Qu G, Ren C, Yan P, Zhou C, Yue B
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2024;57:e13152
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2024;57:e13152
Characterization and optimization of variability in a human colonic epithelium culture model.
Pike CM, Zwarycz B, McQueen BE, Castillo M, Barron C, Morowitz JM, Levi JA, Phadke D, Balik-Meisner M, Mav D, Shah R, Cunningham Glasspoole DL, Laetham R, Thelin W, Bunger MK, Boazak EM
ALTEX 2024;41(3):425-438
ALTEX 2024;41(3):425-438
Cell Membrane-Coated Nanotherapeutics for the Targeted Treatment of Acute and Chronic Colitis.
Li S, Chen L, Wu T, Wu J, Yang H, Ju Q, Liu Z, Chen W, Zhang D, Hao Y
Biomaterials research 2024;28:0102
Biomaterials research 2024;28:0102
Vaporization of perfluorocarbon attenuates sea-water-drowning-induced acute lung injury by deactivating the NLRP3 inflammasomes in canines.
Su CC, Zhang ZR, Liu JX, Meng JG, Ma XQ, Mo ZF, Ren JB, Liang ZX, Yang Z, Li CS, Chen LA
Experimental biology and medicine (Maywood, N.J.) 2024;249:10104
Experimental biology and medicine (Maywood, N.J.) 2024;249:10104
α-Mangostin reduces hypertension in spontaneously hypertensive rats and inhibits EMT and fibrosis in Ang II-induced HK-2 cells.
Xu Y, Wu J, Gao L, Lin H, Yang Z, Liu X, Niu Y
International journal of medical sciences 2024;21(9):1681-1688
International journal of medical sciences 2024;21(9):1681-1688
Matrix Metalloproteinase 11 Promotes Migration and Invasion of Colorectal Cancer by Elevating Slug Protein.
Pan C, Dai J, Wei Y, Yang L, Ding Z, Wang X, He J
International journal of medical sciences 2024;21(11):2170-2188
International journal of medical sciences 2024;21(11):2170-2188
Knockdown of ribosomal protein L22-like 1 arrests the cell cycle and promotes apoptosis in colorectal cancer.
Li C, Du X, Zhang H, Liu S
CytoJournal 2024;21:45
CytoJournal 2024;21:45
Cryptotanshinone Inhibits Bladder Cancer Cell Malignant Progression in a Lipopolysaccharide-Induced Inflammatory Microenvironment through NLRP3 Inhibition.
Tang C, Guo X, Li Y, Yi Y, Tang Z, Zhang Q, Luo B, Chen K, Liang K, Li G
Mediators of inflammation 2024;2024:8828367
Mediators of inflammation 2024;2024:8828367
TSPAN6 reinforces the malignant progression of glioblastoma via interacting with CDK5RAP3 and regulating STAT3 signaling pathway.
Zhang C, Du FH, Wang RX, Han WB, Lv X, Zeng LH, Chen GQ
International journal of biological sciences 2024;20(7):2440-2453
International journal of biological sciences 2024;20(7):2440-2453
RUNX1-PDIA5 Axis Promotes Malignant Progression of Glioblastoma by Regulating CCAR1 Protein Expression.
Ji Q, Tu Z, Liu J, Zhou Z, Li F, Zhu X, Huang K
International journal of biological sciences 2024;20(11):4364-4381
International journal of biological sciences 2024;20(11):4364-4381
METTL16 Promotes Stability of SYNPO2L mRNA and leading to Cancer Cell Lung Metastasis by Secretion of COL10A1 and attract the Cancer-Associated Fibroblasts.
Wu J, Ouyang P, Huang R, Cui Y, Yang Z, Xu W, Ma R, Xiang G, Zeng W, Wu W, Li J
International journal of biological sciences 2024;20(11):4128-4145
International journal of biological sciences 2024;20(11):4128-4145
Hypoxia-driven TNS4 fosters HNSCC tumorigenesis by stabilizing integrin α5β1 complex and triggering FAK-mediated Akt and TGFβ signaling pathways.
Zhao X, Mai Z, Liu L, Lu Y, Cui L, Yu J
International journal of biological sciences 2024;20(1):231-248
International journal of biological sciences 2024;20(1):231-248
Irisin ameliorates UUO-induced renal interstitial fibrosis through TGF-β1/periostin/MMP-2 signaling pathway.
Wang Y, Deng X, Wei J, Yang Z, Du Y, Song S, Shi Y, Wu H
PloS one 2024;19(6):e0299389
PloS one 2024;19(6):e0299389
Interference with mitochondrial metabolism could serve as a potential therapeutic strategy for advanced prostate cancer.
Wu C, Zhu H, Zhang Y, Ding L, Wang J
PloS one 2024;19(4):e0290753
PloS one 2024;19(4):e0290753
The H2Valdien derivatives regulate the epithelial-mesenchymal transition of hepatoma carcinoma cells through the Hedgehog signaling pathway.
Zhao X, Shao X, Huang X, Dang C, Wang R, Li H
Open medicine (Warsaw, Poland) 2024;19(1):20240954
Open medicine (Warsaw, Poland) 2024;19(1):20240954
PTTG1 induces pancreatic cancer cell proliferation and promotes aerobic glycolysis by regulating c-myc.
Wang Y, Hu J, Chen C, Li Y
Open life sciences 2024;19(1):20220813
Open life sciences 2024;19(1):20220813
Combined miR-181a-5p and Ag Nanoparticles are Effective Against Oral Cancer in a Mouse Model.
Xu G, Song X, Wang X, Xue R, Yan X, Qin L, Chang X, Gao J, Chen Z, Song G
International journal of nanomedicine 2024;19:9227-9253
International journal of nanomedicine 2024;19:9227-9253
Nebulization of Hypoxic hUCMSC-EVs Attenuates Airway Epithelial Barrier Defects in Chronic Asthma Mice by Transferring CAV-1.
Luo X, Wang Y, Mao Y, Xu X, Gu W, Li W, Mao C, Zheng T, Dong L
International journal of nanomedicine 2024;19:10941-10959
International journal of nanomedicine 2024;19:10941-10959
miR-34b-5p suppresses the epithelial-mesenchymal transition and metastasis in endometrial cancer AN3CA cells by targeting ZEB1.
Shi L, Yang D, Dong H, Zhang X, Yang C
International journal of clinical and experimental pathology 2024;17(4):137-150
International journal of clinical and experimental pathology 2024;17(4):137-150
Pan-Cancer Screening and Validation of CALU's Role in EMT Regulation and Tumor Microenvironment in Triple-Negative Breast Cancer.
Chen SL, Hu D, Chen TZ, Shen SY, Zhao CF, Wang C, Tong SY, Liu Z, Lin SH, Jin LX, He YB, Zhang ZZ
Journal of inflammation research 2024;17:6743-6764
Journal of inflammation research 2024;17:6743-6764
Progerin Inhibits the Proliferation and Migration of Melanoma Cells by Regulating the Expression of Paxillin.
Liu W, Huang X, Luo W, Liu X, Chen W
OncoTargets and therapy 2024;17:227-242
OncoTargets and therapy 2024;17:227-242
WTAP knockdown inhibits cell migration through regulating SNAIL1 expression in colorectal cancer.
Han J, Zhang J, Shi H, Wen X
American journal of translational research 2024;16(12):8023-8031
American journal of translational research 2024;16(12):8023-8031
Heparan sulfate 6-O-sulfotransferase 2 promotes gastric cancer progression by modulating the TGF-β/smad2/3 pathway.
Wu S, Xu C, Sun W, Xu Q, Zhou F, Jia R, Xu H
American journal of translational research 2024;16(12):7924-7936
American journal of translational research 2024;16(12):7924-7936
Human umbilical cord mesenchymal stem cells derived-exosomes alleviate LPS-induced cervical inflammation and epithelial-mesenchymal transition.
Yi C, Wang H, Din MAU, Xia Y, Akanyibah FA, Mao F
American journal of translational research 2024;16(11):6903-6913
American journal of translational research 2024;16(11):6903-6913
NEDD1 overexpression increases cell proliferation, tumor immune escape, and drug resistance in LUAD.
Zhuo T, Wu Z, Chen S, Yang C, Huang H, Gan J, Lyu J, Xiao J, Li Z, Qin S, Wu Y
Journal of Cancer 2024;15(9):2460-2474
Journal of Cancer 2024;15(9):2460-2474
KRT80 Promotes Lung Adenocarcinoma Progression and Serves as a Substrate for VCP.
Huang S, Tong W, Yang B, Ma L, Zhang J, Wang C, Xu L, Mei J
Journal of Cancer 2024;15(8):2229-2244
Journal of Cancer 2024;15(8):2229-2244
Pan-Cancer Analysis of PGAM1 and Its Experimental Validation in Uveal Melanoma Progression.
Niu W, Yang Y, Teng Y, Zhang N, Li X, Qin Y
Journal of Cancer 2024;15(7):2074-2094
Journal of Cancer 2024;15(7):2074-2094
Integrative Omics Analysis Reveals Metabolic Features of Ground-Glass Opacity-Associated Lung Cancer.
Shi S, Luo D, Yang Y, Wang X
Journal of Cancer 2024;15(7):1848-1862
Journal of Cancer 2024;15(7):1848-1862
LncRNA PRKCA-AS1 promotes LUAD progression and function as a ceRNA to regulate S100A16 by sponging miR-508-5p.
Wu C, Yang J, Lin X, Wu J, Yang C, Chen S
Journal of Cancer 2024;15(6):1718-1730
Journal of Cancer 2024;15(6):1718-1730
IPCEF1: Expression Patterns, Clinical Correlates and New Target of Papillary Thyroid Carcinoma.
Yin D, Wang K, Zhao J, Yao J, Han X, Yan B, Dong J, Liao L
Journal of Cancer 2024;15(19):6434-6451
Journal of Cancer 2024;15(19):6434-6451
DOK1 facilitates the advancement of ccRCC.
Xie W, Zhang Y, Shu B, Zhang Z, Zhang R
Journal of Cancer 2024;15(19):6213-6222
Journal of Cancer 2024;15(19):6213-6222
The transcription factor ZNF248 promotes colorectal cancer metastasis by binding to ZEB1.
Ren Y, Sun X, Chen X, Shao S, Tang J, Xu Z, Xu Y, Kang H, Wang L
Journal of Cancer 2024;15(16):5440-5450
Journal of Cancer 2024;15(16):5440-5450
DPP7 as a Potential Therapeutic Marker for Colorectal Cancer.
Ma L, Yang H, Wu S, Wang C, Mei J
Journal of Cancer 2024;15(16):5425-5439
Journal of Cancer 2024;15(16):5425-5439
MPP7 mediates EMT via Wnt/β-catenin pathway to promote polarity changes in epithelial ovarian cancer cells.
Tao C, Ni X
Journal of Cancer 2024;15(14):4490-4502
Journal of Cancer 2024;15(14):4490-4502
Hypoxia-responsive gene F3 Promotes GBM Cell Proliferation and Migration through Activating NF-κB/p65 Signaling Pathway.
Yu A, Wang Y, Qin J, Lei J, Bao W, Dong Z
Journal of Cancer 2024;15(14):4477-4489
Journal of Cancer 2024;15(14):4477-4489
Elevated RACGAP1 Expression Enhances Malignant Potential in Lung Adenocarcinoma and Serves as a Prognostic Factor.
Lai W, Su Y, Li Y, Zuo Y, He K, Zhang T, Peng D, Wang W
Journal of Cancer 2024;15(13):4244-4258
Journal of Cancer 2024;15(13):4244-4258
CSF2 Impairs Nrf2 Signaling through the Akt/Mtor Pathway in the Development of Bladder Cancer.
Yu X, Li S, Ke S, Ye C, Wang Q, Wang H, Wang L
Journal of Cancer 2024;15(11):3242-3253
Journal of Cancer 2024;15(11):3242-3253
PSAT1 mediated EMT of colorectal cancer cells by regulating Pl3K/AKT signaling pathway.
Wang M, Zhang H, Lu Z, Su W, Tan Y, Wang J, Jia X
Journal of Cancer 2024;15(10):3183-3198
Journal of Cancer 2024;15(10):3183-3198
NUP155 and NDC1 interaction in NSCLC: a promising target for tumor progression.
Li KM, Meng LF, Yang ZH, Hu WT
Frontiers in pharmacology 2024;15:1514367
Frontiers in pharmacology 2024;15:1514367
Danshen injection ameliorates unilateral ureteral obstruction-induced renal fibrosis by inhibiting ferroptosis via activating SIRT1/GPX4 pathway.
Cao Y, Zhao H, Lin S, Chen J, Xiong J, Zeng Z, Long Z, Su Y, Zhong Y, Zhao L, Zhang M, Wu J, Zhou Y, Zhou J
Frontiers in pharmacology 2024;15:1503628
Frontiers in pharmacology 2024;15:1503628
ABCA1 promote tumor environment heterogeneity via epithelial mesenchymal transition in Huh7 and HepG2 liver cancer cell.
Yu D, Guo F, Zhang Q, Yu H, Wang W, Chen Y
Frontiers in pharmacology 2024;15:1498528
Frontiers in pharmacology 2024;15:1498528
Macranthoidin B restrains the epithelial-mesenchymal transition through COX-2/PGE(2) pathway in endometriosis.
Ding Y, Yang X, Wei Q, Bi X, Zhang Y, Ma Y, Yang M, Xu X, Li C, Wang Q, Chen Y
Frontiers in pharmacology 2024;15:1492098
Frontiers in pharmacology 2024;15:1492098
The mechanism of PDE7B inhibiting the development of hepatocellular carcinoma through oxidative stress.
Luo Y, Gao H, Zhao J, Chen L, Shao J, Ju L
Frontiers in immunology 2024;15:1469740
Frontiers in immunology 2024;15:1469740
PFKFB3 deprivation attenuates the cisplatin resistance via blocking its autophagic elimination in colorectal cancer cells.
Li Q, Ma J, Zhang Y, Sun F, Li W, Shen W, Ai Z, Li C, Wang S, Wei X, Yan S
Frontiers in pharmacology 2024;15:1433137
Frontiers in pharmacology 2024;15:1433137
Thonningianin A ameliorated renal interstitial fibrosis in diabetic nephropathy mice by modulating gut microbiota dysbiosis and repressing inflammation.
Zhang S, Zhang S, Bai X, Wang Y, Liu Y, Liu W
Frontiers in pharmacology 2024;15:1389654
Frontiers in pharmacology 2024;15:1389654
Heat acclimation with probiotics-based ORS supplementation alleviates heat stroke-induced multiple organ dysfunction via improving intestinal thermotolerance and modulating gut microbiota in rats.
Li L, Chen J, Wang Y, Pei Y, Ren L, Dai X, Li J, Ma J, Wang M, Chang W, Chen J, Song Q, Xu S
Frontiers in microbiology 2024;15:1385333
Frontiers in microbiology 2024;15:1385333
Identifying and assessing a prognostic model based on disulfidptosis-related genes: implications for immune microenvironment and tumor biology in lung adenocarcinoma.
Wang J, Liu K, Li J, Zhang H, Gong X, Song X, Wei M, Hu Y, Li J
Frontiers in immunology 2024;15:1371831
Frontiers in immunology 2024;15:1371831
Integrated analysis reveals crosstalk between pyroptosis and immune regulation in renal fibrosis.
Bai F, Han L, Yang J, Liu Y, Li X, Wang Y, Jiang R, Zeng Z, Gao Y, Zhang H
Frontiers in immunology 2024;15:1247382
Frontiers in immunology 2024;15:1247382
The long non-coding RNA CCAT1 promotes erlotinib resistance in cholangiocarcinoma by inducing epithelial-mesenchymal transition via the miR-181a-5p/ROCK2 axis.
Zhou W, Li X, Zhang B, Peng H, Quan C, Xiao X, Luo M, Huang Y, Xu D, Huang K, Jin Q, Lu S
American journal of cancer research 2024;14(6):2852-2867
American journal of cancer research 2024;14(6):2852-2867
Extracellular putrescine can augment the epithelial-mesenchymal transition of gastric cancer cells by promoting MAL2 expression by elevating H3K27ac in its promoter region.
Bi C, Li C, Xing L, Lu Z, Liu H, Hu T, Wang B, Liu C
American journal of cancer research 2024;14(6):2805-2822
American journal of cancer research 2024;14(6):2805-2822
Resveratrol restrains colorectal cancer metastasis by regulating miR-125b-5p/TRAF6 signaling axis.
Gao X, Zhu Y, Lv T, Luo M, Jiang Y, Sun L, Zheng S, Jiang D, Ruan S
American journal of cancer research 2024;14(5):2390-2407
American journal of cancer research 2024;14(5):2390-2407
FSH induces EMT in ovarian cancer via ALKBH5-regulated Snail m6A demethylation.
Xu X, Zhuang X, Yu H, Li P, Li X, Lin H, Teoh JP, Chen Y, Yang Y, Cheng Y, Chen W, Fu X
Theranostics 2024;14(5):2151-2166
Theranostics 2024;14(5):2151-2166
POLR2J expression promotes glioblastoma malignancy by regulating oxidative stress and the STAT3 signaling pathway.
Zheng XL, Li ZD, Luo KZ, Li YL, Liu YH, Shen SY, Shen FY, Li WY, Chen GQ, Zhang C, Zeng LH
American journal of cancer research 2024;14(5):2037-2054
American journal of cancer research 2024;14(5):2037-2054
SSH3 promotes pancreatic cancer proliferation and migration by activating the notch signaling pathway.
Yang C, Quan G, Zhang S, Jiang J
American journal of cancer research 2024;14(4):1815-1830
American journal of cancer research 2024;14(4):1815-1830
High glucose-induced NCAPD2 upregulation promotes malignant phenotypes and regulates EMT via the Wnt/β-catenin signaling pathway in HCC.
Mai Y, Liao C, Wang S, Zhou X, Meng L, Chen C, Qin Y, Deng G
American journal of cancer research 2024;14(4):1685-1711
American journal of cancer research 2024;14(4):1685-1711
FLNB overexpression promotes tumor progression and associates with immune suppression, evasion and stemness in pancreatic cancer.
Fan G, Yan Q, Chen Y, Han M, Wu Z, Ruan S, Zhuang H, Gou Q, Hou B
American journal of cancer research 2024;14(2):709-726
American journal of cancer research 2024;14(2):709-726
MAFG-DT promotes prostate cancer bone metastasis through activation of the Wnt/β-catenin pathway.
Wang C, Zhou Z, Ye Y, Zhou L, Wang J, Zhang Z
Frontiers in oncology 2024;14:1461546
Frontiers in oncology 2024;14:1461546
Identification of hub genes within the CCL18 signaling pathway in hepatocellular carcinoma through bioinformatics analysis.
Mao J, Tao Y, Wang K, Sun H, Zhang M, Jin L, Pan Y
Frontiers in oncology 2024;14:1371990
Frontiers in oncology 2024;14:1371990
Early short-term hypoxia promotes epidermal cell migration by activating the CCL2-ERK1/2 pathway and epithelial-mesenchymal transition during wound healing.
Jin L, Zhou S, Zhao S, Long J, Huang Z, Zhou J, Zhang Y
Burns & trauma 2024;12:tkae017
Burns & trauma 2024;12:tkae017
Hypoxia macrophage-derived exosomal miR-26b-5p targeting PTEN promotes the development of keloids.
Dai S, Xu M, Pang Q, Sun J, Lin X, Chu X, Guo C, Xu J
Burns & trauma 2024;12:tkad036
Burns & trauma 2024;12:tkad036
The long noncoding RNA MIR4435-2HG enhances the migration, promotion, and glycolysis of nonsmall cell lung cancer cells by targeting the miR-371a-5p/SOX2/PI3K/Akt axis.
Yang J, Su Y, Wang Y, Gao K, Li C, Li M
SAGE open medicine 2024;12:20503121241289290
SAGE open medicine 2024;12:20503121241289290
Intermittent protein restriction before but not after the onset of diabetic kidney disease attenuates disease progression in mice.
Peng X, Liu M, Wu Y, Fan W, Hou Y, Kong Y, Liu Y, Zhang X, Shan C, Sun H, Yang Y
Frontiers in nutrition 2024;11:1383658
Frontiers in nutrition 2024;11:1383658
Circ_0007386 Promotes the Progression of Hepatocellular Carcinoma Through the miR-507/ CCNT2 Axis.
Feng Y, Liang L, Jia W, Wang J, Xu C, Zhu D, Xu B, Zhao W, Ling X, Zhou Y, Kong L, Ding W
Journal of hepatocellular carcinoma 2024;11:1095-1112
Journal of hepatocellular carcinoma 2024;11:1095-1112
The prognostic value and its relationship with immune infiltration of ACLY in clear cell renal cell carcinoma.
Yin B, Liu Q, Zheng Y, Gao H, Lin Y, Zhao Z
Translational oncology 2024 Sep;47:102056
Translational oncology 2024 Sep;47:102056
Cinobufacini enhances the therapeutic response of 5-Fluorouracil against gastric cancer by targeting cancer stem cells via AKT/GSK-3β/β-catenin signaling axis.
Sun J, Zhang S, Wang M, Cheng H, Wang Y, He S, Zuo Q, Wang N, Li Q, Wang M
Translational oncology 2024 Sep;47:102054
Translational oncology 2024 Sep;47:102054
ACAT1 suppresses clear cell renal cell carcinoma progression by AMPK mediated fatty acid metabolism.
Zheng M, Zhang S, Zhou J, Lin M, Liao Y
Translational oncology 2024 Sep;47:102043
Translational oncology 2024 Sep;47:102043
ETV4 promotes the progression of cholangiocarcinoma by regulating glycolysis via the TGF-β signaling.
Liu F, Wang Q, Wang Z, Zhang S, Ni Q, Chang H
Translational oncology 2024 Sep;47:102035
Translational oncology 2024 Sep;47:102035
TTYH3 Promotes Cervical Cancer Progression by Activating the Wnt/β-Catenin Signaling Pathway.
Huang X, Li Q, Zheng X, Jiang C
Cancer investigation 2024 Sep;42(8):726-739
Cancer investigation 2024 Sep;42(8):726-739
HIF-1α and adaptor protein LIM and senescent cell antigen-like domains protein 1 axis promotes tubulointerstitial fibrosis by interacting with vimentin in angiotensin II-induced hypertension.
Ni WJ, Li ZL, Wen XL, Ji JL, Liu H, Yin Q, Jiang LY, Zhang YL, Wen Y, Tang TT, Jiang W, Lv LL, Gan WH, Liu BC, Wang B
British journal of pharmacology 2024 Sep;181(17):3098-3117
British journal of pharmacology 2024 Sep;181(17):3098-3117
Mefunidone alleviates silica-induced inflammation and fibrosis by inhibiting the TLR4-NF-κB/MAPK pathway and attenuating pyroptosis in murine macrophages.
Long L, Dai X, Yao T, Zhang X, Jiang G, Cheng X, Jiang M, He Y, Peng Z, Hu G, Tao L, Meng J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117216
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Sep;178:117216
Daphnetin induces ferroptosis in ovarian cancer by inhibiting NAD(P)H:Quinone oxidoreductase 1 (NQO1).
Ma N, Zhang M, Hu J, Wei Z, Zhang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155876
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155876
PRM1201 effectively inhibits colorectal cancer metastasis via shaping gut microbiota and short- chain fatty acids.
Jia R, Shao S, Zhang P, Yuan Y, Rong W, An Z, Lv S, Feng Y, Liu N, Feng Q, Wang Y, Li Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155795
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155795
Mechanism of Zhenwu Decoction modulating TLR4/NF-κB/HIF-1α loop through miR-451 to delay renal fibrosis in type 2 CRS.
Xu X, Wang Y, Song Q, Zheng H, Lv J, Fu Z, Mao X, Li Y, Wu H, Zhang B
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155632
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155632
KDM1A, a potent and selective target, for the treatment of DNMT3A-deficient non-small cell lung cancer.
Zhao Y, Zheng Y, Fu J, Zhang J, Shao H, Liu S, Lai J, Zhou X, Liang R, Jia L, Cui W, Yang J, Wu C, Wang L
British journal of cancer 2024 Sep;131(4):655-667
British journal of cancer 2024 Sep;131(4):655-667
GelMA loaded with exosomes from human minor salivary gland organoids enhances wound healing by inducing macrophage polarization.
Qian J, Lu E, Xiang H, Ding P, Wang Z, Lin Z, Pan B, Zhang C, Zhao Z
Journal of nanobiotechnology 2024 Sep 6;22(1):550
Journal of nanobiotechnology 2024 Sep 6;22(1):550
Mitochondrial dysfunction-associated alveolar epithelial senescence is involved in CdCl(2)-induced COPD-like lung injury.
Peng K, Yao YX, Lu X, Wang WJ, Zhang YH, Zhao H, Wang H, Xu DX, Tan ZX
Journal of hazardous materials 2024 Sep 5;476:135103
Journal of hazardous materials 2024 Sep 5;476:135103
BUB1 induces AKT/mTOR pathway activity to promote EMT induction in human small cell lung cancer.
Wang M, You L, Su Z, He Y, Li D, Liu Z
Scientific reports 2024 Sep 4;14(1):20654
Scientific reports 2024 Sep 4;14(1):20654
CXCL16 promotes proliferation of head and neck squamous cell carcinoma by regulating GPX1-mediated antioxidant levels.
He R, Jiang H, Zhang C, Chen Y, Liu W, Deng X, Zhu X, Liu Y, Zheng C, Zhang Y, Shao C, Duan Y, Xu J
Journal of Zhejiang University. Science. B 2024 Sep 30;26(1):92-106
Journal of Zhejiang University. Science. B 2024 Sep 30;26(1):92-106
CRABP2 promotes cell migration and invasion by activating PI3K/AKT and MAPK signalling pathways via upregulating LAMB3 in prostate cancer.
Wang R, Liao Z, Liu C, Yu S, Xiang K, Wu T, Feng J, Ding S, Yu T, Cheng G, Li S
Journal of biochemistry 2024 Sep 30;176(4):313-324
Journal of biochemistry 2024 Sep 30;176(4):313-324
Clarithromycin attenuates airway epithelial-mesenchymal transition in ovalbumin-induced asthmatic mice through modulation of Kv1.3 channels and PI3K/Akt signaling.
Sun B, Shen K, Zhao R, Li Y, Lin J
International immunopharmacology 2024 Sep 30;139:112624
International immunopharmacology 2024 Sep 30;139:112624
E3 ubiquitin ligase BTBD3 inhibits tumorigenesis of colorectal cancer by regulating the TYRO3/Wnt/β-catenin signaling axis.
Ye K, Wang PC, Chen YX, Huang QZ, Chi P
Cancer cell international 2024 Sep 3;24(1):306
Cancer cell international 2024 Sep 3;24(1):306
KIFC3 promotes the proliferation, migration and invasion of non-small cell lung cancer through the PI3K/AKT signaling pathway.
Ma Y, Zhang Y, Jiang X, Guan J, Wang H, Zhang J, Tong Y, Qiu X, Zhou R
Scientific reports 2024 Sep 3;14(1):20471
Scientific reports 2024 Sep 3;14(1):20471
Activin A plays an essential role in migration and proliferation of hepatic stellate cells via Smad3 and calcium signaling.
Zhang W, Zhu L, Fang F, Zhang F, Wang R, Yang K, Liu Y, Cui X
Scientific reports 2024 Sep 3;14(1):20419
Scientific reports 2024 Sep 3;14(1):20419
CircSEC24B activates autophagy and induces chemoresistance of colorectal cancer via OTUB1-mediated deubiquitination of SRPX2.
Wang D, Li Y, Chang W, Feng M, Yang Y, Zhu X, Liu Z, Fu Y
Cell death & disease 2024 Sep 27;15(9):693
Cell death & disease 2024 Sep 27;15(9):693
FBXO11 Mediates Ubiquitination of ZEB1 and Modulates Epithelial-to-Mesenchymal Transition in Lung Cancer Cells.
Zhao X, Han Z, Liu R, Li Z, Mei L, Jin Y
Cancers 2024 Sep 26;16(19)
Cancers 2024 Sep 26;16(19)
Reduced syncytin-1 regulates trophoblast invasion and apoptosis in preeclampsia.
Wang YN, Chen XL, Yang J, Gong XX, Zhang HF, Zhang YM, Zeng DF, Chen PS, Chen HB
Placenta 2024 Sep 26;155:32-41
Placenta 2024 Sep 26;155:32-41
Mesenchymal stem cells in tumor microenvironment: drivers of bladder cancer progression through mitochondrial dynamics and energy production.
Yang E, Jing S, Wang F, Wang H, Fu S, Yang L, Tian J, Golijanin DJ, El-Deiry WS, Cheng L, Wang Z
Cell death & disease 2024 Sep 20;15(9):688
Cell death & disease 2024 Sep 20;15(9):688
Da-Chai-Hu-Tang Formula inhibits the progression and metastasis in HepG2 cells through modulation of the PI3K/AKT/STAT3-induced cell cycle arrest and apoptosis.
Duan ZW, Liu Y, Zhang PP, Hu JY, Mo ZX, Liu WQ, Ma X, Zhou XH, Wang XH, Hu XH, Wei SL
Journal of ethnopharmacology 2024 Sep 15;331:118293
Journal of ethnopharmacology 2024 Sep 15;331:118293
Cigarette smoke extract induces malignant transformation and DNA damage via c-MET phosphorylation in human bronchial epithelial cells.
Wang L, Chen J, Li Q, Liu A, Lei Z, Li M, Yasin P, Yang S, Ren J, Hu Y, Ren Y, Cheng S, Liu Z
Ecotoxicology and environmental safety 2024 Sep 15;283:116985
Ecotoxicology and environmental safety 2024 Sep 15;283:116985
A novel biomarker GATM suppresses proliferation and malignancy of cholangiocarcinoma cells by modulating the JNK/c-Jun signalling pathways.
Yu Y, Gan W, Xiong J, Li J
Heliyon 2024 Sep 15;10(17):e37344
Heliyon 2024 Sep 15;10(17):e37344
Mechanisms of Yiai Fuzheng formula in the treatment of triple-negative breast cancer based on UPLC-Q-Orbitrap-HRMS, network pharmacology, and experimental validation.
Li R, Ke H, Liu P, Yang Q, Li Y, Ke L, Wang X, Wu C, Zhang Y
Heliyon 2024 Sep 15;10(17):e36579
Heliyon 2024 Sep 15;10(17):e36579
Effects and mechanisms of Polygonati Rhizoma polysaccharide on potassium oxonate and hypoxanthine-induced hyperuricemia in mice.
Zhang N, Zhang B, Chen X, Zhang Y, Wang Y, Lu S, Zhang H, Chen Y, Jiang H, Zhou H
International journal of biological macromolecules 2024 Sep 13;280(Pt 1):135550
International journal of biological macromolecules 2024 Sep 13;280(Pt 1):135550
Design, Synthesis, and Biological Evaluation of Potent EZH2/LSD1 Dual Inhibitors for Prostate Cancer.
Le M, Lu W, Tan X, Luo B, Yu T, Sun Y, Guo Z, Huang P, Zhu D, Wu Q, Ganesan A, Wen S
Journal of medicinal chemistry 2024 Sep 12;67(17):15586-15605
Journal of medicinal chemistry 2024 Sep 12;67(17):15586-15605
SQLE-a promising prognostic biomarker in cervical cancer: implications for tumor malignant behavior, cholesterol synthesis, epithelial-mesenchymal transition, and immune infiltration.
Zhao YC, Li YF, Qiu L, Jin SZ, Shen YN, Zhang CH, Cui J, Wang TJ
BMC cancer 2024 Sep 11;24(1):1133
BMC cancer 2024 Sep 11;24(1):1133
Promotion of apoptosis in melanoma cells by taxifolin through the PI3K/AKT signaling pathway: Screening of natural products using WGCNA and CMAP platforms.
Wang Y, Chen SJ, Ma T, Long Q, Chen L, Xu KX, Cao Y
International immunopharmacology 2024 Sep 10;138:112517
International immunopharmacology 2024 Sep 10;138:112517
Anti-cancer effects of nitazoxanide in epithelial ovarian cancer in-vitro and in-vivo.
Yang X, Liu Z, Wang X, Tian W, Zhao T, Yang Q, Li W, Yang L, Yang H, Jia Y
Chemico-biological interactions 2024 Sep 1;400:111176
Chemico-biological interactions 2024 Sep 1;400:111176
Curcumin blunts epithelial-mesenchymal transition to alleviate invasion and metastasis of prostate cancer through the JARID1D demethylation.
Xie Q, Hu Y, Zhang C, Zhang C, Qin J, Zhao Y, An Q, Zheng J, Shi C
Cancer cell international 2024 Sep 1;24(1):303
Cancer cell international 2024 Sep 1;24(1):303
METTL3-dependent m6A modification facilitates decreased endometrial decidualization via attenuation of MET in endometriosis.
Xiong W, Jin J, Liu Y
Reproduction (Cambridge, England) 2024 Sep 1;168(3)
Reproduction (Cambridge, England) 2024 Sep 1;168(3)
miR-141-3p attenuates inflammation and oxidative stress-induced pulmonary fibrosis in ARDS via the Keap1/Nrf2/ARE signaling pathway.
Long G, Zhang Q, Yang X, Sun H, Ji C
Immunologic research 2024 Oct;72(5):1003-1017
Immunologic research 2024 Oct;72(5):1003-1017
The activation of adenosine monophosphate-activated protein kinase inhibits the migration of tongue squamous cell carcinoma cells by targeting Claudin-1 via epithelial-mesenchymal transition.
Zhou XY, Liu QM, Li Z, Liu XY, Zhao QW, Wang Y, Wu FH, Zhao G, Sun R, Guo XH
Animal models and experimental medicine 2024 Oct;7(5):606-616
Animal models and experimental medicine 2024 Oct;7(5):606-616
MIA3 promotes the degradation of GSH (glutathione) by binding to CHAC1, thereby promoting the progression of hepatocellular carcinoma.
Wanbiao Z, Jing M, Shi Z, Tengxiang C, Xueke Z, Haiyang L
Molecular and cellular biochemistry 2024 Oct;479(10):2769-2784
Molecular and cellular biochemistry 2024 Oct;479(10):2769-2784
Matrine inhibits invasion and migration of gallbladder cancer via regulating the PI3K/AKT signaling pathway.
Mo RL, Li Z, Zhang P, Sheng MH, Han GC, Sun DQ
Naunyn-Schmiedeberg's archives of pharmacology 2024 Oct;397(10):8129-8143
Naunyn-Schmiedeberg's archives of pharmacology 2024 Oct;397(10):8129-8143
Biomimetic nanocomplex based corneal neovascularization theranostics.
Ye J, Cheng Y, Wen X, Han Y, Wei X, Wu Y, Chen C, Su M, Cai S, Pan J, Liu G, Chu C
Journal of controlled release : official journal of the Controlled Release Society 2024 Oct;374:50-60
Journal of controlled release : official journal of the Controlled Release Society 2024 Oct;374:50-60
Validation of quercetin in the treatment of colon cancer with diabetes via network pharmacology, molecular dynamics simulations, and in vitro experiments.
Zhou W, Cao W, Wang M, Yang K, Zhang X, Liu Y, Zhang P, Zhang Z, Cao G, Chen B, Xiong M
Molecular diversity 2024 Oct;28(5):2947-2965
Molecular diversity 2024 Oct;28(5):2947-2965
Multi-omics analysis reveals BZW1's regulation of EMT via the Wnt pathway in lung adenocarcinoma.
Lai W, Ping Z, Chen Y, Wang J, Liu Y, Zou S, Wang J, Zhang T, Ren W, Wang W
Journal of cellular and molecular medicine 2024 Oct;28(20):e70163
Journal of cellular and molecular medicine 2024 Oct;28(20):e70163
IGFBP7 regulates cell proliferation and migration through JAK/STAT pathway in gastric cancer and is regulated by DNA and RNA methylation.
Mo W, Deng L, Cheng Y, Ge S, Wang J
Journal of cellular and molecular medicine 2024 Oct;28(19):e70080
Journal of cellular and molecular medicine 2024 Oct;28(19):e70080
Regulation of Fuzheng Huayu capsule on inhibiting the fibrosis-associated hepatocellular carcinogenesis.
Zhang WQ, Sun JX, Lan ST, Sun XM, Guo YJ, Wen BC, Chen J, Liu G
Journal of Asian natural products research 2024 Oct;26(10):1219-1238
Journal of Asian natural products research 2024 Oct;26(10):1219-1238
Cdk1/p53/p21 feedback loop mechanisms in the pathogenesis of interstitial cystitis/bladder pain syndrome.
Wang K, Shi J, Chen Z, Xue D, He X
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167305
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167305
An agonist of the adenosine A(2A) receptor, CGS21680, promotes corneal epithelial wound healing via the YAP signalling pathway.
Sun Q, Jiang N, Yao R, Song Y, Li Z, Wang W, Chen J, Guo W
British journal of pharmacology 2024 Oct;181(19):3779-3795
British journal of pharmacology 2024 Oct;181(19):3779-3795
The expression and role of SUZ12 in lung adenocarcinoma.
Hu X, Hu C, Zhong P
Cancer medicine 2024 Oct;13(19):e70190
Cancer medicine 2024 Oct;13(19):e70190
Targeting Neuraminidase 4 Attenuates Kidney Fibrosis in Mice.
Xiao PT, Hao JH, Kuang YJ, Dai CX, Rong XL, Jiang LL, Xie ZS, Zhang L, Chen QQ, Liu EH
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Oct;11(39):e2406936
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Oct;11(39):e2406936
Polymeric immunoglobulin receptor promotes Th2 immune response in the liver by increasing cholangiocytes derived IL-33: a diagnostic and therapeutic biomarker of biliary atresia.
Li Y, Li TY, Qiao Q, Zhang MT, Tong MX, Xu LF, Zhang ZB
EBioMedicine 2024 Oct;108:105344
EBioMedicine 2024 Oct;108:105344
Single-cell analysis reveals alternations between the aged and young mice prostates.
Li Y, Ding Y, Hou Y, Liu L, Liu Z, Yao Z, Shi P, Li J, Chen K, Hu J
Biomarker research 2024 Oct 9;12(1):117
Biomarker research 2024 Oct 9;12(1):117
Coke oven emissions exacerbate allergic asthma by promoting ferroptosis in airway epithelial cells.
Chen X, Chen H, Zhang P, Ju Q, Wu Z, Xu N, Bi Q, Yang S, Ji J, Yu D, Zhao Y
Journal of hazardous materials 2024 Oct 5;478:135542
Journal of hazardous materials 2024 Oct 5;478:135542
ATF4/NUPR1 axis promotes cancer cell survival and mediates immunosuppression in clear cell renal cell carcinoma.
Lu Y, Chen W, Xuan Y, Li X, Wu S, Wang H, Guo T, Wang C, Tian S, Li H, Lai D, Zhao W, Huang X, Zhao X, Wang B, Zhang X, Li H, Huang Y, Ma X
Discover oncology 2024 Oct 31;15(1):607
Discover oncology 2024 Oct 31;15(1):607
LncRNA FEZF1-AS1 promotes pulmonary fibrosis via up-regulating EZH2 and targeting miR-200c-3p to regulate the ZEB1 pathway.
Liu M, Song L, Lai Y, Gao F, Man J
Scientific reports 2024 Oct 30;14(1):26044
Scientific reports 2024 Oct 30;14(1):26044
The prognostic significance of twist in pancreatic cancer and its role in cancer promotion through the regulation of the immune microenvironment and EMT mechanisms.
Li Q, Liu Y, Zhi R, Wang Y
Discover oncology 2024 Oct 26;15(1):593
Discover oncology 2024 Oct 26;15(1):593
RHOF promotes Snail1 lactylation by enhancing PKM2-mediated glycolysis to induce pancreatic cancer cell endothelial-mesenchymal transition.
Zhao R, Yi Y, Liu H, Xu J, Chen S, Wu D, Wang L, Li F
Cancer & metabolism 2024 Oct 26;12(1):32
Cancer & metabolism 2024 Oct 26;12(1):32
Erianin inhibits the progression of pancreatic cancer by directly targeting AKT and ASK1.
Liu R, Qiu M, Deng X, Zhang M, Gao Z, Wang Y, Mei H, Zhai M, Zhang Q, Hao J, Yang Z, Wang H
Cancer cell international 2024 Oct 25;24(1):348
Cancer cell international 2024 Oct 25;24(1):348
CircGNAO1 suppresses hepatocellular carcinoma progression and metastasis via sponging miR-182-5p and regulating FOXO1 expression.
Ju L, Luo Y, Shan J, Lu R, Chen L, Shao J, Bian Z, Yao M
International immunopharmacology 2024 Oct 25;140:112873
International immunopharmacology 2024 Oct 25;140:112873
Construction of an autophagy-related genes risk model as predicting prognosis: BAG1 suppresses growth of clear cell renal cell carcinoma.
Guo J, Chen Q, Han S, Wang T, Xia K, Yu B, Qiu T, Zhou J
International immunopharmacology 2024 Oct 25;140:112737
International immunopharmacology 2024 Oct 25;140:112737
SASS6 promotes tumor proliferation and is associated with TP53 and immune infiltration in lung adenocarcinoma.
Li Z, He L, Li J, Qian J, Wu Z, Zhu Y, Zhuo T, Nong J, Liang H, Zheng H, Huang W, Huang J, Cao J
Clinical and experimental medicine 2024 Oct 24;24(1):243
Clinical and experimental medicine 2024 Oct 24;24(1):243
MYO6 contributes to tumor progression and enzalutamide resistance in castration-resistant prostate cancer by activating the focal adhesion signaling pathway.
Zheng S, Hong Z, Tan Y, Wang Y, Li J, Zhang Z, Feng T, Hong Z, Lin G, Ye D
Cell communication and signaling : CCS 2024 Oct 24;22(1):517
Cell communication and signaling : CCS 2024 Oct 24;22(1):517
[Aumolertinib combined with anlotinib inhibits proliferation of non-small cell lung cancer cells by down-regulating the PI3K/AKT pathway].
Yang Y, Liu X, Liu W, Zhou X, Zhang Z, Hu Y, Liu P, Li X, Liu H, Li S
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2024 Oct 20;44(10):1965-1975
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2024 Oct 20;44(10):1965-1975
Ubiquitin Ligase TRIM22 Inhibits Ovarian Cancer Malignancy via TCF4 Degradation.
Tao T, Zhang Y, Guan C, Wang S, Liu X, Wang M
Molecular cancer research : MCR 2024 Oct 2;22(10):943-956
Molecular cancer research : MCR 2024 Oct 2;22(10):943-956
Chromosome 8q24 amplification associated with human hepatocellular carcinoma predicts MYC/ZEB1/MIZ1 transcriptional regulation.
Chahine JJ, Davis SS, Culfaci S, Kallakury BV, Tuma PL
Scientific reports 2024 Oct 18;14(1):24488
Scientific reports 2024 Oct 18;14(1):24488
Effects of Nitric Oxide on Bladder Detrusor Overactivity through the NRF2 and HIF-1α Pathways: A Rat Model Induced by Metabolic Syndrome and Ovarian Hormone Deficiency.
Lin HY, Lu JH, Lin RJ, Chueh KS, Juan TJ, Mao JW, Lee YC, Chuang SM, Shen MC, Sun TW, Juan YS
International journal of molecular sciences 2024 Oct 16;25(20)
International journal of molecular sciences 2024 Oct 16;25(20)
Integrative Omics Uncovers Low Tumorous Magnesium Content as A Driver Factor of Colorectal Cancer.
Zhang R, Hu M, Liu Y, Li W, Xu Z, He S, Lu Y, Gong Y, Wang X, Hai S, Li S, Qi S, Li Y, Shu Y, Du D, Zhang H, Xu H, Zhou Z, Lei P, Chen HN, Dai L
Genomics, proteomics & bioinformatics 2024 Oct 15;22(4)
Genomics, proteomics & bioinformatics 2024 Oct 15;22(4)
HIF-1α knockdown suppresses breast cancer metastasis via epithelial mesenchymal transition Abrogation.
Zhao J, Zhang H, Liu Y, Lu G, Wang Z, Mo Q, Wang G, Shen Y, Jiao L
Heliyon 2024 Oct 15;10(19):e37900
Heliyon 2024 Oct 15;10(19):e37900
SMEK1 promotes clear cell renal cell carcinoma progression via EGFR tyrosine-kinase dependent pathway.
Wang J, Bi W, Lv R, Wang Z, Xin Q, Li K, Chen Y, Liu Q, Zhang X
Cancer letters 2024 Oct 1;601:217148
Cancer letters 2024 Oct 1;601:217148
FAM83D promotes the progression of 4NQO-induced esophageal carcinoma via inhibiting FBWX7.
Li J, Tian J, Ma M, Qin Z, Cao B, Yang J, Wang X, Yang X
Experimental cell research 2024 Oct 1;442(2):114252
Experimental cell research 2024 Oct 1;442(2):114252
Regulation of cervical cancer via G15-mediated inhibition of G protein-coupled estrogen receptor.
Zhu Z, Nie X, Deng L, Ding J, Chen J, Zhu J, Yin X, Guo B, Zhang F
Anti-cancer drugs 2024 Oct 1;35(9):817-829
Anti-cancer drugs 2024 Oct 1;35(9):817-829
NOD2 reduces the chemoresistance of melanoma by inhibiting the TYMS/PLK1 signaling axis.
Yun F, Wu N, Yi X, Zhang X, Feng Y, Ni Q, Gai Y, Li E, Yang Z, Zhang Q, Sai B, Kuang Y, Zhu Y
Cell death & disease 2024 Oct 1;15(10):720
Cell death & disease 2024 Oct 1;15(10):720
Circ_0084615 promotes epithelial-mesenchymal transition-mediated tumor progression in hepatocellular carcinoma.
Wu Y, Peng L
Annals of gastroenterological surgery 2024 Nov;8(6):1107-1117
Annals of gastroenterological surgery 2024 Nov;8(6):1107-1117
Liquiritigenin inhibits the migration, invasion, and EMT of prostate cancer through activating ER stress.
Wang C, Liu B, Dan W, Wei Y, Li M, Guo C, Zhang Y, Xie H
Archives of biochemistry and biophysics 2024 Nov;761:110184
Archives of biochemistry and biophysics 2024 Nov;761:110184
PM(10) dysregulates epithelial barrier function in human corneal epithelial cells that is restored by antioxidant SKQ1.
Somayajulu M, Wright R, Muhammed F, McClellan SA, Ibrahim A, Hazlett LD
Toxicology and applied pharmacology 2024 Nov;492:117122
Toxicology and applied pharmacology 2024 Nov;492:117122
CypA/TAF15/STAT5A/miR-514a-3p feedback loop drives ovarian cancer metastasis.
Li Y, Yang H, Li A, Chen B, Wang Y, Song Z, Tan H, Li H, Feng Q, Zhou Y, Li S, Zeng L, Lan T
Oncogene 2024 Nov;43(49):3570-3585
Oncogene 2024 Nov;43(49):3570-3585
NEU4-mediated desialylation enhances the activation of the oncogenic receptors for the dissemination of ovarian carcinoma.
Shi J, Zhou R, Wang S, Liu Y, Tian B, Liu Y, Chen Y, Hu T, Mu Y, Wang S, Shao X, Yan J, Qu P, Wei D, Yang S, Shi Y, Li J, Wang L
Oncogene 2024 Nov;43(49):3556-3569
Oncogene 2024 Nov;43(49):3556-3569
Effects of daphnetin on the mechanism of epithelial-mesenchymal transition induced by HMGB1 in human lung adenocarcinoma cells (A549 cell line).
Gong SQ, Liu H, Wu JL, Xu JX
Biotechnology & genetic engineering reviews 2024 Nov;40(3):1489-1510
Biotechnology & genetic engineering reviews 2024 Nov;40(3):1489-1510
Data-mining-based biomarker evaluation and experimental validation of SHTN1 for bladder cancer.
Wang Y, Wang J, Zeng T, Qi J
Cancer genetics 2024 Nov;288-289:43-53
Cancer genetics 2024 Nov;288-289:43-53
Long non-coding RNA AC010457.1 promotes the growth and EMT of gastric cancer via the PI3K/AKT axis.
Qian C, Chen Y, Zhao Z, Hu Y, Yi J, Chen S, He J, Chen J, Xue W
Pathology, research and practice 2024 Nov;263:155646
Pathology, research and practice 2024 Nov;263:155646
Novel curcumin derivatives N17 exert anti-cancer effects through the CSNK1G3/AKT axis in triple-negative breast cancer.
Huai Z, Li Z, Xue W, Li S, Huang Y, Cao X, Wei Q, Wang Y
Biochemical pharmacology 2024 Nov;229:116472
Biochemical pharmacology 2024 Nov;229:116472
Dysregulated lncSNHG12 suppresses the invasion and migration of trophoblasts by regulating Dio2/Snail axis to involve in recurrent spontaneous abortion.
Wang Z, Yan S, Liao S, Zhang Y, Wu S, Zhou M, Jin W, Zhang Y, Qi X, Yang C, Yang J, Ding J
Biochemical pharmacology 2024 Nov;229:116459
Biochemical pharmacology 2024 Nov;229:116459
High glucose-induced senescence contributes to tubular epithelial cell damage in diabetic nephropathy.
Xu D, Moru P, Liao K, Song W, Yang P, Zang D, Cai C, Zhou H
Experimental gerontology 2024 Nov;197:112609
Experimental gerontology 2024 Nov;197:112609
Microbiota-derived succinic acid mediates attenuating effect of dietary tomato juice supplementation on steatohepatitis through enhancing intestinal barrier.
Song X, Sun J, Yue Y, Li D, Chen F
Food research international (Ottawa, Ont.) 2024 Nov;196:115123
Food research international (Ottawa, Ont.) 2024 Nov;196:115123
Disruption of blood-brain barrier and endothelial-to-mesenchymal transition are attenuated by Astragalus polysaccharides mediated through upregulation of ETS1 expression in experimental autoimmune encephalomyelitis.
Lu Q, Ma J, Zhao Y, Ding G, Wang Y, Qiao X, Cheng X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117521
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Nov;180:117521
Cancer-Associated Endocrine Cells Participate in Pancreatic Carcinogenesis.
Chen Y, Yin X, Xu R, Ruze R, Song J, Yin C, Hu C, Wang C, Xu Q, Zhao Y
Gastroenterology 2024 Nov;167(6):1167-1182.e23
Gastroenterology 2024 Nov;167(6):1167-1182.e23
LncRNA H19 accelerates renal fibrosis by negatively regulating the let-7b-5p/TGF-βR1/COL1A1 axis.
Li HY, Xu XY, Lv SH, Chen W, Wang Y, Fu Y, Yang JP
Cellular signalling 2024 Nov;123:111373
Cellular signalling 2024 Nov;123:111373
MTFR2 accelerates hepatocellular carcinoma mediated by metabolic reprogramming via the Akt signaling pathway.
Bao Z, Yang M, Guo Y, Ge Q, Zhang H
Cellular signalling 2024 Nov;123:111366
Cellular signalling 2024 Nov;123:111366
Overexpression of microRNA-611 inhibits TGF-β-induced epithelial-mesenchymal transition and migration in lung cancer cells through MAPKAP1.
Ke B, Huang Y, Gong Y, Zhong H, Shi L
Cellular signalling 2024 Nov;123:111357
Cellular signalling 2024 Nov;123:111357
Elevated ITGA3 expression serves as a novel prognostic biomarker and regulates tumor progression in cervical cancer.
Tan W, Chen G, Ci Q, Deng Z, Gu R, Yang D, Dai F, Liu H, Cheng Y
Scientific reports 2024 Nov 7;14(1):27063
Scientific reports 2024 Nov 7;14(1):27063
NSUN2 Promotes Head and Neck Squamous Cell Carcinoma Progression by Targeting EMT-Related Gene LAMC2 in an m(5)C-YBX1-Dependent Manner.
Huang S, Cao C, Tang D, Liu Y, Zhou W, Liu L, Zheng X, He Q, Wang A
Biomedicines 2024 Nov 6;12(11)
Biomedicines 2024 Nov 6;12(11)
ZNF652 exerts a tumor suppressor role in lung cancer by transcriptionally downregulating cyclin D3.
Xie C, Zhou X, Wu J, Chen W, Ren D, Zhong C, Meng Z, Shi Y, Zhu J
Cell death & disease 2024 Nov 5;15(11):792
Cell death & disease 2024 Nov 5;15(11):792
HOXC12 promotes the invasion and migration of gastric cancer cells by upregulating SALL4 and activating Wnt/β-catenin signaling pathway.
Zhang J, Hou N, Rao D, Chen Q, Ning Z, Lu M
Discover oncology 2024 Nov 5;15(1):620
Discover oncology 2024 Nov 5;15(1):620
Naringin Alleviates Intestinal Fibrosis by Inhibiting ER Stress-Induced PAR2 Activation.
Liu J, Xu L, Wang L, Wang Q, Yu L, Zhang S
Inflammatory bowel diseases 2024 Nov 4;30(11):1946-1956
Inflammatory bowel diseases 2024 Nov 4;30(11):1946-1956
Controlled release of hydrogel-encapsulated mesenchymal stem cells-conditioned medium promotes functional liver regeneration after hepatectomy in metabolic dysfunction-associated steatotic liver disease.
Kasahara N, Teratani T, Doi J, Yokota S, Shimodaira K, Kaneko Y, Ohzawa H, Sakuma Y, Sasanuma H, Fujimoto Y, Urahashi T, Yoshitomi H, Yamaguchi H, Kitayama J, Sata N
Stem cell research & therapy 2024 Nov 4;15(1):395
Stem cell research & therapy 2024 Nov 4;15(1):395
Nuclear translocation of SIRT4 mediates deacetylation of U2AF2 to modulate renal fibrosis through alternative splicing-mediated upregulation of CCN2.
Yang G, Xiang J, Yang X, Liu X, Li Y, Li L, Kang L, Liang Z, Yang S
eLife 2024 Nov 4;13
eLife 2024 Nov 4;13
Exacerbation of pulmonary fibrosis following acute lung injury via activin-A production by recruited alveolar macrophages.
Pan T, Feng Y, Li Y, Yang Y, Zhou J, Song Y
Journal of thoracic disease 2024 Nov 30;16(11):7709-7728
Journal of thoracic disease 2024 Nov 30;16(11):7709-7728
Downregulated KLF4, induced by m6A modification, aggravates intestinal barrier dysfunction in inflammatory bowel disease.
Zhu X, Wang J, Zhang H, Yue H, Zhu J, Li J, Wang K, Shen K, Yang K, Leng X, Xi Q, Shi T
Cellular and molecular life sciences : CMLS 2024 Nov 29;81(1):470
Cellular and molecular life sciences : CMLS 2024 Nov 29;81(1):470
CLIP170 enhancing FOSL1 expression via attenuating ubiquitin-mediated degradation of β-catenin drives renal cell carcinoma progression.
Huang Y, Wen Z, Tao S, Yu Z, Wang X, Li X, Gao L
Cellular and molecular life sciences : CMLS 2024 Nov 28;81(1):467
Cellular and molecular life sciences : CMLS 2024 Nov 28;81(1):467
Epithelial differentiation of gingival mesenchymal stem cells enhances re-epithelialization for full-thickness cutaneous wound healing.
Li Y, Dong L, Chen Y, Cai W, Yang G, Wang Y
Stem cell research & therapy 2024 Nov 28;15(1):455
Stem cell research & therapy 2024 Nov 28;15(1):455
Tumor Protein D53 (TPD53): Involvement in Malignant Transformation of Low-Malignant Oral Squamous Cell Carcinoma Cells.
Watanabe M, Mukudai Y, Kindaichi N, Nara M, Yamada K, Abe Y, Houri A, Shimane T, Shirota T
Biomedicines 2024 Nov 28;12(12)
Biomedicines 2024 Nov 28;12(12)
Intravenous injection of BMSCs modulate tsRNA expression and ameliorate lung remodeling in COPD mice.
Jin T, Liu X, Li G, Sun S, Xie L
Stem cell research & therapy 2024 Nov 25;15(1):450
Stem cell research & therapy 2024 Nov 25;15(1):450
DsbA-L activates TGF-β1/SMAD3 signaling and M2 macrophage polarization by stimulating AKT1 and NLRP3 to promote pulmonary fibrosis.
Wang J, Xia Z, Qing B, Chen Y, Gu L, Chen H, Ge Z, Yuan Y
Molecular medicine (Cambridge, Mass.) 2024 Nov 23;30(1):228
Molecular medicine (Cambridge, Mass.) 2024 Nov 23;30(1):228
The role of disulfidptosis-associated LncRNA-LINC01137 in Osteosarcoma Biology and its regulatory effects on macrophage polarization.
Tang N, Chen Y, Su Y, Zhang S, Huang T
Functional & integrative genomics 2024 Nov 22;24(6):219
Functional & integrative genomics 2024 Nov 22;24(6):219
Methionine deprivation inhibits glioma proliferation and EMT via the TP53TG1/miR-96-5p/STK17B ceRNA pathway.
Li J, Liu R, Hu H, Huang Y, Shi Y, Li H, Chen H, Cai M, Wang N, Yan T, Wang K, Liu H
NPJ precision oncology 2024 Nov 21;8(1):270
NPJ precision oncology 2024 Nov 21;8(1):270
Arginine methylation-dependent TRIM47 stability mediated by CARM1 promotes the metastasis of hepatocellular carcinoma.
Tang Y, Meng X, Luo X, Yao W, Tian L, Zhang Z, Zhao Y, Xiao J, Zhu H, Hu J
Cell death discovery 2024 Nov 20;10(1):477
Cell death discovery 2024 Nov 20;10(1):477
Effect and underlying mechanism of a photochemotherapy dual-function nanodrug delivery system for head and neck squamous cell carcinoma.
Lin Q, Liu HM, Wu LZ, Yu DD, Hua CY, Zou Y, Jiao WE, Li XP, Chen SM
Journal of translational medicine 2024 Nov 19;22(1):1043
Journal of translational medicine 2024 Nov 19;22(1):1043
LncRNA AP001007 protects human renal tubular epithelial HK-2 cells and kidney organoids from LPS-induced injury.
Lin S, Ren Z, Li L, Xia S, Yang R, Ye H
Scientific reports 2024 Nov 19;14(1):28578
Scientific reports 2024 Nov 19;14(1):28578
PLGA microspheres carrying EMSCs-CM for the effective treatment of murine ulcerative colitis.
Yang W, Zhang X, Wang Z, Zheng X, Wu W, Chen Q
International immunopharmacology 2024 Nov 15;141:112883
International immunopharmacology 2024 Nov 15;141:112883
Role of HDAC3 in the epithelial-mesenchymal transition of retinal pigment epithelium cells: Implications for proliferative vitreoretinopathy.
Zou W, Huang C, Chen Y, Tang J, Li Q, Fang Q, Ma Y, Wu W, Feng S
Heliyon 2024 Nov 15;10(21):e39333
Heliyon 2024 Nov 15;10(21):e39333
FXR deficiency induced ferroptosis via modulation of the CBP-dependent p53 acetylation to suppress breast cancer growth and metastasis.
Huang P, Zhao H, Dai H, Li J, Pan X, Pan W, Xia C, Liu F
Cell death & disease 2024 Nov 14;15(11):826
Cell death & disease 2024 Nov 14;15(11):826
Pancreatic cancer-derived exosomal miR-510 promotes macrophage M2 polarization and facilitates cancer cell aggressive phenotypes.
Wang T, Ye L, Zhou Y, Zhang X, Li R, Zhou Y, Weng J, Mo Q, Yu Y
Human cell 2024 Nov 12;38(1):17
Human cell 2024 Nov 12;38(1):17
Unconjugated bilirubin promotes uric acid restoration by activating hepatic AMPK pathway.
Zhang Y, Chen Y, Chen X, Gao Y, Luo J, Lu S, Li Q, Li P, Bai M, Jiang T, Zhang N, Zhang B, Chen B, Zhou H, Jiang H, Lin N
Free radical biology & medicine 2024 Nov 1;224:644-659
Free radical biology & medicine 2024 Nov 1;224:644-659
Prohibitin 2 confers NADPH oxidase 1-mediated cytosolic oxidative signaling to promote gastric cancer progression by ERK activation.
Xu L, Meng L, Xiang W, Wang X, Yang J, Shu C, Zhao XH, Rong Z, Ye Y
Free radical biology & medicine 2024 Nov 1;224:130-143
Free radical biology & medicine 2024 Nov 1;224:130-143
TRAIP suppressed apoptosis and cell cycle to promote prostate cancer proliferation via TRAF2-PI3K-AKT pathway activation.
Gu Y, Liang C
International urology and nephrology 2024 May;56(5):1639-1648
International urology and nephrology 2024 May;56(5):1639-1648
NPAS2, transcriptionally activated by ARRB1, promotes the malignant behaviours of lung adenocarcinoma cells and regulates the reprogramming of glucose metabolism.
Wang S, Huang C, Zheng Y, Wu X, Zhong Y
Clinical and experimental pharmacology & physiology 2024 May;51(5):e13860
Clinical and experimental pharmacology & physiology 2024 May;51(5):e13860
Synergistic anticancer effects of ginsenoside CK and gefitinib against gefitinib-resistant NSCLC by regulating the balance of angiogenic factors through HIF-1α/VEGF.
Song X, Wang L, Cai P, Xu Y, Liu Q, Fan D
Toxicology and applied pharmacology 2024 May;486:116938
Toxicology and applied pharmacology 2024 May;486:116938
microRNA-141-3p Suppressed the Progression of the Clear Cell Renal Cell Carcinoma by Targeting Transforming Growth Factor Beta 2 Gene Expression.
Hu X, Li D, Zhan J, Yang C, Wang P, Meng X, Xu S, Che X, Xu L
DNA and cell biology 2024 May;43(5):245-257
DNA and cell biology 2024 May;43(5):245-257
Protein regulator of cytokinesis 1 accentuates cholangiocarcinoma progression via mTORC1-mediated glycolysis.
Zhang C, Qin C
Human cell 2024 May;37(3):739-751
Human cell 2024 May;37(3):739-751
AMBRA1 promotes intestinal inflammation by antagonizing PP4R1/PP4c mediated IKK dephosphorylation in an autophagy-independent manner.
Xu W, Hua Z, Wang Y, Tang W, Ou W, Liu F, Yang Y, Ding W, Wang Z, Cui L, Ge W, Gu Y, Wang X, Chen Y, Liu CY, Du P
Cell death and differentiation 2024 May;31(5):618-634
Cell death and differentiation 2024 May;31(5):618-634
The Jagged-1/Notch1 Signaling Pathway Promotes the Construction of Tissue-Engineered Heart Valves.
Liu K, Wei ZY, Zhong XH, Liu X, Chen H, Pan Y, Zeng W
Tissue engineering. Part A 2024 May;30(9-10):381-392
Tissue engineering. Part A 2024 May;30(9-10):381-392
YTHDF1 promotes gallbladder cancer progression via post-transcriptional regulation of the m6A/UHRF1 axis.
Chen J, Bai X, Zhang W, Yan Z, Liu Y, Zhou S, Wu X, He X, Yang A
Journal of cellular and molecular medicine 2024 May;28(9):e18328
Journal of cellular and molecular medicine 2024 May;28(9):e18328
Circular RNA hsa_circ_0094976 modulates GPR155 to inhibit gastric adenocarcinoma malignant characteristics by targeting miR-223-3p.
Liu L, Li X, Song L, Yang Y, Li B
Pathology, research and practice 2024 May;257:155325
Pathology, research and practice 2024 May;257:155325
Daurisoline suppress glioma progression by inhibiting autophagy through PI3K/AKT/mTOR pathway and increases TMZ sensitivity.
Yin HT, Hui-Lu, Yang JH, Li Q, Li M, Zhao QQ, Wen ZP
Biochemical pharmacology 2024 May;223:116113
Biochemical pharmacology 2024 May;223:116113
The circadian clock gene, BMAL1, promotes radiosensitization in nasopharyngeal carcinoma by inhibiting the epithelial-to-mesenchymal transition via the TGF-β1/Smads/Snail1 axis.
Li Y, Zhou Y, Zhao C, Liu L, He Q, Shang K, Xu X, Luo X, Zhou D, Jin F
Oral oncology 2024 May;152:106798
Oral oncology 2024 May;152:106798
Riboflavin protects against pancreatic cancer metastasis by targeting TGF-β receptor 1.
Zhao J, Liu X, Jin X, Dong T, Gao X, Wang J, Li Y, Ma E
Bioorganic chemistry 2024 May;146:107274
Bioorganic chemistry 2024 May;146:107274
Paris polyphylla ethanol extract and polyphyllin I ameliorate adenomyosis by inhibiting epithelial-mesenchymal transition.
Shi YX, Xu L, Wang X, Zhang KK, Zhang CY, Liu HY, Ding PP, Shi W, Liu ZY
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 May;127:155461
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 May;127:155461
Machine learning combined with single-cell analysis reveals predictive capacity and immunotherapy response of T cell exhaustion-associated lncRNAs in uterine corpus endometrial carcinoma.
Jiang F, Tao Z, Zhang Y, Xie X, Bao Y, Hu Y, Ding J, Wu C
Cellular signalling 2024 May;117:111077
Cellular signalling 2024 May;117:111077
SOAT1 regulates cholesterol metabolism to induce EMT in hepatocellular carcinoma.
Fu R, Xue W, Liang J, Li X, Zheng J, Wang L, Zhang M, Meng J
Cell death & disease 2024 May 9;15(5):325
Cell death & disease 2024 May 9;15(5):325
β-catenin turnover is regulated by Nek10-mediated tyrosine phosphorylation in A549 lung adenocarcinoma cells.
Dutt P, Haider N, Mouaaz S, Podmore L, Stambolic V
Proceedings of the National Academy of Sciences of the United States of America 2024 May 7;121(19):e2300606121
Proceedings of the National Academy of Sciences of the United States of America 2024 May 7;121(19):e2300606121
Modified Lichong decoction intervenes in colorectal cancer by modulating the intestinal flora and the Wnt/β-catenin signaling pathway.
Liu L, Zhao M, Lang X, Jia S, Kang X, Liu Y, Liu J
Journal of cancer research and clinical oncology 2024 May 6;150(5):234
Journal of cancer research and clinical oncology 2024 May 6;150(5):234
Design, synthesis and evaluation of a pyrazolo[3,4-d]pyrimidine derivative as a novel and potent TGFβ1R1 inhibitor.
Wang Y, Liu Y, Zhang Y, Zhang Z, Xu L, Wang J, Yang Y, Hu B, Yao Y, Wei M, Wang J, Tang B, Zhang K, Liu S, Yang G
European journal of medicinal chemistry 2024 May 5;271:116395
European journal of medicinal chemistry 2024 May 5;271:116395
Human amnion mesenchymal stem cells promote endometrial repair via paracrine, preferentially than transdifferentiation.
Huang X, Yang X, Huang J, Wei L, Mao Y, Li C, Zhang Y, Chen Q, Wu S, Xie L, Sun C, Zhang W, Wang J
Cell communication and signaling : CCS 2024 May 31;22(1):301
Cell communication and signaling : CCS 2024 May 31;22(1):301
CD112 is an epithelial-to-mesenchymal transition-related and immunological biomarker in pan-cancer.
Zhang H, Lu J, Dong Q, Wang G, Wang X
Translational cancer research 2024 May 31;13(5):2387-2407
Translational cancer research 2024 May 31;13(5):2387-2407
Integrated network pharmacology and experimental verification to explore the potential mechanism of San Ying decoction for treating triple-negative breast cancer.
Yang X, Li F, Shi Y, Wu Y, Yang R, Liu X, Zhang Y, Zhang G, Ma M, Luo Z, Han X, Xie Y, Liu S
Acta biochimica et biophysica Sinica 2024 May 25;56(5):763-775
Acta biochimica et biophysica Sinica 2024 May 25;56(5):763-775
miR-1202 regulates BPH-1 cell proliferation, apoptosis, and epithelial-to-mesenchymal transition through targeting HMGCL.
Wang Z, Yin X, Yang P, Gong B, Liu H
Acta biochimica et biophysica Sinica 2024 May 25;56(5):675-687
Acta biochimica et biophysica Sinica 2024 May 25;56(5):675-687
Astragalus polysaccharides augment BMSC homing via SDF-1/CXCR4 modulation: a novel approach to counteract peritoneal mesenchymal transformation and fibrosis.
Wang F, Dai H, Zhou Z, Shan Y, Yu M, Sun J, Sheng L, Huang L, Meng X, You Y, Sheng M
BMC complementary medicine and therapies 2024 May 24;24(1):204
BMC complementary medicine and therapies 2024 May 24;24(1):204
Exosomal circPOLQ promotes macrophage M2 polarization via activating IL-10/STAT3 axis in a colorectal cancer model.
Sun Z, Xu Y, Shao B, Dang P, Hu S, Sun H, Chen C, Wang C, Liu J, Liu Y, Hu J
Journal for immunotherapy of cancer 2024 May 23;12(5)
Journal for immunotherapy of cancer 2024 May 23;12(5)
Methylation-regulated tumor suppressor gene PDE7B promotes HCC invasion and metastasis through the PI3K/AKT signaling pathway.
Du Y, Xu Y, Guo X, Tan C, Zhu X, Liu G, Lyu X, Bei C
BMC cancer 2024 May 22;24(1):624
BMC cancer 2024 May 22;24(1):624
Targeting the HSP47-collagen axis inhibits brain metastasis by reversing M2 microglial polarization and restoring anti-tumor immunity.
Wang L, Li C, Zhan H, Li S, Zeng K, Xu C, Zou Y, Xie Y, Zhan Z, Yin S, Zeng Y, Chen X, Lv G, Han Z, Zhou D, Zhou D, Yang Y, Zhou A
Cell reports. Medicine 2024 May 21;5(5):101533
Cell reports. Medicine 2024 May 21;5(5):101533
The role of USP7-YY1 interaction in promoting colorectal cancer growth and metastasis.
Shao ZY, Yang WD, Qiu H, He ZH, Lu MR, Shen Q, Ding J, Zheng JN, Bai J
Cell death & disease 2024 May 20;15(5):347
Cell death & disease 2024 May 20;15(5):347
IL-1β promotes esophageal squamous cell carcinoma growth and metastasis through FOXO3A by activating the PI3K/AKT pathway.
Chen S, Yang Y, Zheng Z, Zhang M, Chen X, Xiao N, Liu H
Cell death discovery 2024 May 18;10(1):238
Cell death discovery 2024 May 18;10(1):238
JAM3 promotes cervical cancer metastasis by activating the HIF-1α/VEGFA pathway.
Peng J, Chen Y, Yin A
BMC women's health 2024 May 17;24(1):293
BMC women's health 2024 May 17;24(1):293
E3 ubiquitin ligase UBR5 promotes gemcitabine resistance in pancreatic cancer by inducing O-GlcNAcylation-mediated EMT via destabilization of OGA.
Du Y, Yang Z, Shi H, Chen Z, Chen R, Zhou F, Peng X, Hong T, Jiang L
Cell death & disease 2024 May 16;15(5):340
Cell death & disease 2024 May 16;15(5):340
MAP7 drives EMT and cisplatin resistance in ovarian cancer via wnt/β-catenin signaling.
Chen Q, Li S, Fu F, Huang Q, Zhang R
Heliyon 2024 May 15;10(9):e30409
Heliyon 2024 May 15;10(9):e30409
IL-6 regulates epithelial ovarian cancer EMT, invasion, and metastasis by modulating Let-7c and miR-200c through the STAT3/HIF-1α pathway.
Guo QY, Song JN, Chen YM, Yuan HN, Xue WS, Sun Y, Niu XL, Wang Y, Chen X
Medical oncology (Northwood, London, England) 2024 May 14;41(6):155
Medical oncology (Northwood, London, England) 2024 May 14;41(6):155
Loss of KLF15 impairs endometrial receptivity by inhibiting EMT in endometriosis.
Huang Y, Wang Z, Li B, Ke L, Xiong Y, Zhang Y
The Journal of endocrinology 2024 May 1;261(2)
The Journal of endocrinology 2024 May 1;261(2)
lncRNA CERS6-AS1 upregulates the expression of ANLN by sponging miR-424-5p to promote the progression and drug resistance of lung adenocarcinoma.
Ting Z, Wu Z, Yang C, Li Z, Huang H, Gan J, Li N, Li X, Lyu J, Wu Y, Qin S
Non-coding RNA research 2024 Mar;9(1):221-235
Non-coding RNA research 2024 Mar;9(1):221-235
Oral infection with Porphyromonas gingivalis augmented gingival epithelial barrier molecules alteration with aging.
Giri S, Takada A, Paudel D, Uehara O, Kurashige Y, Kuramitsu Y, Furukawa M, Matsushita K, Arakawa T, Nagasawa T, Abiko Y, Furuichi Y
Journal of oral biosciences 2024 Mar;66(1):126-133
Journal of oral biosciences 2024 Mar;66(1):126-133
Curcumin inhibits the invasion and migration of pancreatic cancer cells by upregulating TFPI-2 to regulate ERK- and JNK-mediated epithelial-mesenchymal transition.
Zhai LL, Li WB, Chen LJ, Wang W, Ju TF, Yin DL
European journal of nutrition 2024 Mar;63(2):639-651
European journal of nutrition 2024 Mar;63(2):639-651
NLRP3 inflammasome mediates abnormal epithelial regeneration and distal lung remodeling in silica‑induced lung fibrosis.
Zhou H, Zhang Q, Liu C, Fan J, Huang W, Li N, Yang M, Wang H, Xie W, Kong H
International journal of molecular medicine 2024 Mar;53(3)
International journal of molecular medicine 2024 Mar;53(3)
PSMD12 promotes non-small cell lung cancer progression through activating the Nrf2/TrxR1 pathway.
Lv J, Ma S, Wang X, Dang J, Ma F
Genes & genomics 2024 Mar;46(3):263-277
Genes & genomics 2024 Mar;46(3):263-277
Establishment and characterization of a novel hypopharyngeal squamous cell carcinoma cell line CZH1 with genetic abnormalities.
Ma J, Zhu X, Heng Y, Ding X, Tao L, Lu L
Human cell 2024 Mar;37(2):546-559
Human cell 2024 Mar;37(2):546-559
CD74-ROS1 L2026M mutant enhances autophagy through the MEK/ERK pathway to promote invasion, metastasis and crizotinib resistance in non-small cell lung cancer cells.
Xu X, Li Y, Xu R, Meng Y, Li Z, Zuo D, Wu Y
The FEBS journal 2024 Mar;291(6):1199-1219
The FEBS journal 2024 Mar;291(6):1199-1219
Osteopontin-driven partial epithelial-mesenchymal transition governs the development of middle ear cholesteatoma.
Zeng L, Xie L, Hu J, He C, Liu A, Lu X, Zhou W
Cell cycle (Georgetown, Tex.) 2024 Mar;23(5):537-554
Cell cycle (Georgetown, Tex.) 2024 Mar;23(5):537-554
RSK4 promotes the macrophage recruitment and M2 polarization in esophageal squamous cell carcinoma.
He S, Lu M, Zhang L, Wang Z
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):166996
Biochimica et biophysica acta. Molecular basis of disease 2024 Mar;1870(3):166996
MBIP promotes ESCC metastasis by activating MAPK pathway.
Ma Y, Hua Y, Yin X, Jiao Y, Xu E, Yan T, Yang J, Zhang L
Cellular signalling 2024 Mar;115:111040
Cellular signalling 2024 Mar;115:111040
CD146(+)CAFs promote progression of endometrial cancer by inducing angiogenesis and vasculogenic mimicry via IL-10/JAK1/STAT3 pathway.
Yu Z, Zhang Q, Wei S, Zhang Y, Zhou T, Zhang Q, Shi R, Zinovkin D, Pranjol ZI, Zhang J, Wang H
Cell communication and signaling : CCS 2024 Mar 8;22(1):170
Cell communication and signaling : CCS 2024 Mar 8;22(1):170
DOCK1 regulates the malignant biological behavior of endometrial cancer through c-Raf/ERK pathway.
Xie S, Jin Y, Wang J, Li J, Peng M, Zhu X
BMC cancer 2024 Mar 4;24(1):296
BMC cancer 2024 Mar 4;24(1):296
Mechanisms of vemurafenib-induced anti-tumor effects in ATC FRO cells.
Xu J, Xue D, Li Y, Zhou J, Chen H, Fan L
Heliyon 2024 Mar 30;10(6):e27629
Heliyon 2024 Mar 30;10(6):e27629
Metformin alleviates junctional epithelium senescence via the AMPK/SIRT1/autophagy pathway in periodontitis induced by hyperglycemia.
Ye X, Wang Y, Tian Y, Bi R, Li M, Yang C, Zhang L, Gao Y
Heliyon 2024 Mar 30;10(6):e27478
Heliyon 2024 Mar 30;10(6):e27478
Long non-coding RNA LINC01554 overexpression suppresses viability, migration, and invasion of liver cancer cells through regulating miR-148b-3p/EIF4E3.
Ren X, Wang X, Song H, Zhang C, Yuan J, He J, Li J, Wang Z
Heliyon 2024 Mar 30;10(6):e27319
Heliyon 2024 Mar 30;10(6):e27319
Multi-omics cluster defines the subtypes of CRC with distinct prognosis and tumor microenvironment.
Ma Y, Li J, Zhao X, Ji C, Hu W, Ma Y, Qu F, Sun Y, Zhang X
European journal of medical research 2024 Mar 28;29(1):207
European journal of medical research 2024 Mar 28;29(1):207
ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells.
Lu D, Zhi Y, Su H, Lin X, Lin J, Shi Y, Yi W, Hong C, Zhang T, Fu Z, Chen LY, Zhao Z, Li R, Xu Z, Chen W, Wang N, Xu D
Cell reports 2024 Mar 26;43(3):113818
Cell reports 2024 Mar 26;43(3):113818
PELI1: key players in the oncogenic characteristics of pancreatic Cancer.
Fei X, Zhu C, Liu P, Liu S, Ren L, Lu R, Hou J, Gao Y, Wang X, Pan Y
Journal of experimental & clinical cancer research : CR 2024 Mar 25;43(1):91
Journal of experimental & clinical cancer research : CR 2024 Mar 25;43(1):91
IGF2BP3 prevent HMGB1 mRNA decay in bladder cancer and development.
Lv L, Wei Q, Zhang J, Dong Y, Shan Z, Chang N, Zhao Y, Bian P, Yi Q
Cellular & molecular biology letters 2024 Mar 19;29(1):39
Cellular & molecular biology letters 2024 Mar 19;29(1):39
Identification of host protein ENO1 (alpha-enolase) interacting with Cryptosporidium parvum sporozoite surface protein, Cpgp40.
Wang Y, Li N, Liang G, Wang L, Zhang X, Cui Z, Li X, Zhang S, Zhang L
Parasites & vectors 2024 Mar 19;17(1):146
Parasites & vectors 2024 Mar 19;17(1):146
PDE12 disrupts mitochondrial oxidative phosphorylation and mediates mitochondrial dysfunction to induce oral mucosal epithelial barrier damage in oral submucous fibrosis.
Wei Q, Chen L, Luo W, Chen C, Shi Y, Xie J, Xie X, Luo HB
European journal of pharmacology 2024 Mar 15;967:176353
European journal of pharmacology 2024 Mar 15;967:176353
RNA modification-related genes illuminate prognostic signature and mechanism in esophageal squamous cell carcinoma.
Han H, Sun Y, Wei W, Huang Z, Cheng M, Qiu H, Wang J, Zheng S, Liu L, Zhang Q, Zhang C, Ma J, Guo S, Wang Z, Li Z, Jiang X, Lin S, Liu Q, Zhang S
iScience 2024 Mar 15;27(3):109327
iScience 2024 Mar 15;27(3):109327
Rare flavanone-diarylheptanoid hybrids from Typha angustifolia shows anti breast cancer activity via activating TGF-β1/Smad signaling pathway.
Li YP, Liu H, Zhao XC, Tang XL, Shan P, Zhang H
European journal of medicinal chemistry 2024 Mar 15;268:116220
European journal of medicinal chemistry 2024 Mar 15;268:116220
Cancer-associated fibroblast-secreted FGF7 as an ovarian cancer progression promoter.
Feng S, Ding B, Dai Z, Yin H, Ding Y, Liu S, Zhang K, Lin H, Xiao Z, Shen Y
Journal of translational medicine 2024 Mar 15;22(1):280
Journal of translational medicine 2024 Mar 15;22(1):280
Pro-tumorigenic activity of PYCR1 in gastric cancer through regulating the PI3K/AKT signaling.
Xiao H, Huang J, Wu H, Li Y, Wang Y
Heliyon 2024 Mar 15;10(5):e26883
Heliyon 2024 Mar 15;10(5):e26883
SARS-CoV-2 remodels the Golgi apparatus to facilitate viral assembly and secretion.
Zhang J, Kennedy A, de Melo Jorge DM, Xing L, Reid W, Bui S, Joppich J, Rose M, Ercan S, Tang Q, Tai AW, Wang Y
bioRxiv : the preprint server for biology 2024 Mar 15;
bioRxiv : the preprint server for biology 2024 Mar 15;
The circRNA hsa-circ-0013561 regulates head and neck squamous cell carcinoma development via the miR-7-5p/PDK3 axis.
Tian K, Zheng L, Yuan T, Chen X, Chen Q, Xue X, Huang S, He W, Jin M, Zhang Y
Cancer cell international 2024 Mar 1;24(1):91
Cancer cell international 2024 Mar 1;24(1):91
PPP2R1B abolishes colorectal cancer liver metastasis and sensitizes Oxaliplatin by inhibiting MAPK/ERK signaling pathway.
Liu W, Tang J, Gao W, Sun J, Liu G, Zhou J
Cancer cell international 2024 Mar 1;24(1):90
Cancer cell international 2024 Mar 1;24(1):90
OTUD4 promotes the progression of glioblastoma by deubiquitinating CDK1 and activating MAPK signaling pathway.
Ci M, Zhao G, Li C, Liu R, Hu X, Pan J, Shen Y, Zhang G, Li Y, Zhang L, Liang P, Cui H
Cell death & disease 2024 Mar 1;15(3):179
Cell death & disease 2024 Mar 1;15(3):179
Influenza A virus infection disrupts the function of syncytiotrophoblast cells and contributes to adverse pregnancy outcomes.
Wang J, Liu W, Zhuang Y, Yang J, Zhao Y, Hong A, Du J, Kong H, Wang J, Jiang Y, Wang Y
Journal of medical virology 2024 Jun;96(6):e29687
Journal of medical virology 2024 Jun;96(6):e29687
Downregulation of HIGD1B induces mitochondria-mediated apoptosis in gastric cancer cells by inactivating Akt and ERK pathways.
Chen X, Sun B, Li S
Drug development research 2024 Jun;85(4):e22221
Drug development research 2024 Jun;85(4):e22221
ID2 promotes tumor progression and metastasis in thyroid cancer.
Deng Z, Xu M, Ding Z, Kong J, Liu J, Zhang Z, Cao P
Endocrine 2024 Jun;84(3):1051-1063
Endocrine 2024 Jun;84(3):1051-1063
Effect of CHRDL1 on angiogenesis and metastasis of colorectal cancer cells via TGF-β/VEGF pathway.
Li J, Jiang Z, He J, Yang K, Chen J, Deng Q, Li X, Wu F, Xu S, Jiang Z
Molecular carcinogenesis 2024 Jun;63(6):1092-1105
Molecular carcinogenesis 2024 Jun;63(6):1092-1105
Increased FGL1 Expression Predicts Poor Prognosis and Promotes EMT in Head and Neck Squamous Cell Carcinoma.
Pan Z, Hu W, Huang J, Zheng Z, Lin E, Wang P, Mao L
Biochemical genetics 2024 Jun;62(3):2066-2081
Biochemical genetics 2024 Jun;62(3):2066-2081
MYEOV with High Frequencies of Mutations in Head and Neck Cancers Facilitates Cancer Cell Malignant Behaviors.
Ou D, Wu Y, Zhang J, Liu J, Liu Z, Shao M, Guo X, Cui S
Biochemical genetics 2024 Jun;62(3):1657-1674
Biochemical genetics 2024 Jun;62(3):1657-1674
Tweety homolog 3 promotes colorectal cancer progression through mutual regulation of histone deacetylase 7.
Lu P, Deng S, Liu J, Xiao Q, Zhou Z, Li S, Xin J, Shu G, Yi B, Yin G
MedComm 2024 Jun;5(6):e576
MedComm 2024 Jun;5(6):e576
SLC11A1 promotes kidney renal clear cell carcinoma (KIRC) progression by remodeling the tumor microenvironment.
Wu D, Zhou Y, Shi X, Yi X, Sheng Z, Fan L, Ge J, Cheng W, Zhou W, He H, Fu D
Toxicology and applied pharmacology 2024 Jun;487:116975
Toxicology and applied pharmacology 2024 Jun;487:116975
Cysteine and glycine-rich protein 2 is crucial for maintaining the malignant phenotypes of gliomas through its action on Notch signalling cascade.
Liu L, Li F, Zhang L, Cheng Y, Wu L, Tie R, Jiang X, Gao W, Liu B, Wei Y, Chang P, Xu J, Zhao H, Zhang L
Toxicology and applied pharmacology 2024 Jun;487:116969
Toxicology and applied pharmacology 2024 Jun;487:116969
Exploring the regulatory role of FBXL19-AS1 in triple-negative breast cancer through the miR-378a-3p/OTUB2 axis.
Guo C, Zhang M, Jin X, Zhu C, Qian J, Tao M
Cell biochemistry and function 2024 Jun;42(4):e4020
Cell biochemistry and function 2024 Jun;42(4):e4020
A novel mitochondrial unfolded protein response-related risk signature to predict prognosis, immunotherapy and sorafenib sensitivity in hepatocellular carcinoma.
Zhang S, Guo H, Wang H, Liu X, Wang M, Liu X, Fan Y, Tan K
Apoptosis : an international journal on programmed cell death 2024 Jun;29(5-6):768-784
Apoptosis : an international journal on programmed cell death 2024 Jun;29(5-6):768-784
Amentoflavone reverses epithelial-mesenchymal transition in hepatocellular carcinoma cells by targeting p53 signalling pathway axis.
Jian HY, Zhang JT, Liu Z, Zhang Z, Zeng PH
Journal of cellular and molecular medicine 2024 Jun;28(11):e18442
Journal of cellular and molecular medicine 2024 Jun;28(11):e18442
Eosinophil peroxidase promotes bronchial epithelial cells to secrete asthma-related factors and induces the early stage of airway remodeling.
Xu L, Huang X, Chen Z, Yang M, Deng J
Clinical immunology (Orlando, Fla.) 2024 Jun;263:110228
Clinical immunology (Orlando, Fla.) 2024 Jun;263:110228
Lysophosphatidic acid promotes ESCC progression by increasing the level of CCL2 secreted by esophageal epithelial cells.
Ma H, Ma X, Qi L, Zhang Q, Wang T, Guo Q, Li P, Zhang S, Liu S
The journal of gene medicine 2024 Jun;26(6):e3708
The journal of gene medicine 2024 Jun;26(6):e3708
IFNT-induced IRF1 enhances bovine endometrial receptivity by transactivating LIFR.
Ma B, Cui H, Wang X, Feng W, Zhang J, Chen N, Umar T, Zhou H, Liu W, Feng X, Deng G
Journal of reproductive immunology 2024 Jun;163:104212
Journal of reproductive immunology 2024 Jun;163:104212
Hypoxia differently regulates the proportion of ALDH(hi) cells in lung squamous carcinoma H520 and adenocarcinoma A549 cells via the Wnt/β-catenin pathway.
Liu N, Zheng Q, Zhang Y, Wang H, Zhang Z, He L, Wei C, Xia H, Liu Y, Wang X
Thoracic cancer 2024 Jun;15(18):1419-1428
Thoracic cancer 2024 Jun;15(18):1419-1428
Panax notoginseng saponins improve oral submucous fibrosis by inhibiting the Wnt/β-catenin signal pathway.
Hu L, He J, Zhang T, Pan S, Zou H, Lian K, Guo J, Tang Q
Oral surgery, oral medicine, oral pathology and oral radiology 2024 Jun;137(6):651-661
Oral surgery, oral medicine, oral pathology and oral radiology 2024 Jun;137(6):651-661
Hsa_circ_0004214 involved in the epithelial-mesenchymal transition induced by beryllium sulfate through modulating JAK-STAT signaling pathway.
Jin H, Liu Y, Lei Y, Li G, Huang L, Zhang Z
Toxicology research 2024 Jun;13(3):tfae067
Toxicology research 2024 Jun;13(3):tfae067
Glucose regulates the HMGB1 signaling pathway through SIRT1 in glioma.
Wang Y, Wang S, Wang Y, Wang C, Tang Y, Zhang C, Hou S, Yu D, Lin N
Cellular signalling 2024 Jun;118:111137
Cellular signalling 2024 Jun;118:111137
Peptide Transporter 1-Mediated Dipeptide Transport Promotes Hepatocellular Carcinoma Metastasis by Activating MAP4K4/G3BP2 Signaling Axis.
Song F, Zhang Z, Liu W, Xu T, Hu X, Wang Q, Zhang W, Ge L, Zhang C, Hu Q, Qin H, Zhang S, Ren X, Fan W, Zhang Y, Huang P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(24):e2306671
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jun;11(24):e2306671
Mortalin promotes the evolution of androgen-independent prostate cancer through Wnt/β-catenin signaling pathway.
Chang Y, Sui J, Fu Q, Lu Z, Piao Z, Jin T, Zhang M
Cancer cell international 2024 Jun 7;24(1):203
Cancer cell international 2024 Jun 7;24(1):203
POLR1D silencing suppresses lung cancer cells proliferation and migration via inhibition of PI3K-Akt pathway.
Yuan Z, Wang Y, Yang Y, Qin X
Journal of cardiothoracic surgery 2024 Jun 6;19(1):322
Journal of cardiothoracic surgery 2024 Jun 6;19(1):322
Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1-ZEB1 Axis-Mediated Epithelial-Mesenchymal Transition.
Li T, Wei L, Zhang X, Fu B, Zhou Y, Yang M, Cao M, Chen Y, Tan Y, Shi Y, Wu L, Xuan C, Du Q, Hu R
Molecular cancer research : MCR 2024 Jun 4;22(6):538-554
Molecular cancer research : MCR 2024 Jun 4;22(6):538-554
Analysis of cell death-related genes to evaluate the prognostic and immunotherapeutic value in bladder cancer.
Gao M, Guo H, Xu H, Jin X, Liu Y, Chen Z, Wang X
Heliyon 2024 Jun 30;10(12):e33200
Heliyon 2024 Jun 30;10(12):e33200
Extracellular vesicles activated cancer-associated fibroblasts promote lung cancer metastasis through mitophagy and mtDNA transfer.
Zhou Z, Qu C, Zhou P, Zhou Q, Li D, Wu X, Yang L
Journal of experimental & clinical cancer research : CR 2024 Jun 3;43(1):158
Journal of experimental & clinical cancer research : CR 2024 Jun 3;43(1):158
IFI16 promotes the progression of clear cell renal cell carcinoma through the IL6/PI3K/AKT axis.
Lu K, Zhao Y, Li Y, Fu Z, Chen Y, Kong Y, Li G
Journal of translational medicine 2024 Jun 3;22(1):533
Journal of translational medicine 2024 Jun 3;22(1):533
ISG15 promotes tumor progression via IL6/JAK2/STAT3 signaling pathway in ccRCC.
Xie W, Zhang Y, Zhang Z, Li Q, Tao L, Zhang R
Clinical and experimental medicine 2024 Jun 29;24(1):140
Clinical and experimental medicine 2024 Jun 29;24(1):140
NAT1 inhibits liver metastasis of colorectal cancer by regulating EMT and glycolysis.
Gu W, Li C, Shen T, Tong L, Yuan W, Zheng X, Wang T, Wang S, Zhu B, Zhang C, Zhang C
Aging 2024 Jun 24;16(12):10546-10562
Aging 2024 Jun 24;16(12):10546-10562
DNAJC1 facilitates glioblastoma progression by promoting extracellular matrix reorganization and macrophage infiltration.
Zhang H, Zheng W, Chen X, Sa L, Huo Y, Zhang L, Shan L, Wang T
Journal of cancer research and clinical oncology 2024 Jun 22;150(6):315
Journal of cancer research and clinical oncology 2024 Jun 22;150(6):315
Repurposing homoharringtonine for thyroid cancer treatment through TIMP1/FAK/PI3K/AKT signaling pathway.
Xi C, Zhang G, Sun N, Liu M, Ju N, Shen C, Song H, Luo Q, Qiu Z
iScience 2024 Jun 21;27(6):109829
iScience 2024 Jun 21;27(6):109829
Supramolecular artificial Nano-AUTACs enable tumor-specific metabolism protein degradation for synergistic immunotherapy.
Wang Y, Yang L, Yan C, Du Y, Li T, Yang W, Lei L, He B, Gao H, Peppas NA, Cao J
Science advances 2024 Jun 21;10(25):eadn8079
Science advances 2024 Jun 21;10(25):eadn8079
Association of mitochondrial phosphoenolpyruvate carboxykinase with prognosis and immune regulation in hepatocellular carcinoma.
Li C, Zhang ED, Ye Y, Xiao Z, Huang H, Zeng Z
Scientific reports 2024 Jun 18;14(1):14051
Scientific reports 2024 Jun 18;14(1):14051
Calpain 8 as a potential biomarker regulates the progression of pancreatic cancer via EMT and AKT/ERK pathway.
Song N, Cui K, Zeng L, Fan Y, Wang Z, Shi P, Su W, Wang H
Journal of proteomics 2024 Jun 15;301:105182
Journal of proteomics 2024 Jun 15;301:105182
Bidirectional effects of the tryptophan metabolite indole-3-acetaldehyde on colorectal cancer.
Dai Z, Deng KL, Wang XM, Yang DX, Tang CL, Zhou YP
World journal of gastrointestinal oncology 2024 Jun 15;16(6):2697-2715
World journal of gastrointestinal oncology 2024 Jun 15;16(6):2697-2715
SIAH2 is specifically expressed during cervical carcinogenesis, and closely relates to the abnormal proliferation of cervical epithelial cells.
Jing LP, Li M, Xia XY, Zheng X, Chen JY, He J, Zhuang XW
Heliyon 2024 Jun 15;10(11):e31487
Heliyon 2024 Jun 15;10(11):e31487
Baicalein promotes KDM4E to induce BICD1 and inhibit triple-negative breast cancer progression by blocking PAR1 signaling.
Dong Y, He G, Chen K, He X, Pan M, Huang X, Yu X, Xia J
Molecular carcinogenesis 2024 Jul;63(7):1288-1302
Molecular carcinogenesis 2024 Jul;63(7):1288-1302
Parkin deficiency promotes liver cancer metastasis by TMEFF1 transcription activation via TGF-β/Smad2/3 pathway.
Su Q, Wang JJ, Ren JY, Wu Q, Chen K, Tu KH, Zhang Y, Leong SW, Sarwar A, Han X, Zhang M, Dai WF, Zhang YM
Acta pharmacologica Sinica 2024 Jul;45(7):1520-1529
Acta pharmacologica Sinica 2024 Jul;45(7):1520-1529
The inhibition of MARCO by PolyG alleviates pulmonary fibrosis via regulating mitochondrial function in a silicotic rat model.
Chang M, Li N, Zhou Q, Yan Y, Xu W, Zhao Y, Yao S
Environmental toxicology 2024 Jul;39(7):3808-3819
Environmental toxicology 2024 Jul;39(7):3808-3819
MicroRNA-505-3p mediates cell motility of epithelial ovarian cancer via suppressing PEAK1 expression.
Wu Y, Xue L, Xiong W, Li H, Wu J, Xie W, Long Y, Liu Y, Luo C
Journal of biochemical and molecular toxicology 2024 Jul;38(7):e23767
Journal of biochemical and molecular toxicology 2024 Jul;38(7):e23767
Therapeutic potential of vitamin D3 in mitigating high glucose‑induced renal damage: Mechanistic insights into oxidative stress inhibition and TXNIP/NLRP3 signaling pathway blockade.
Li G, He S, Liu T, Zheng N
Experimental and therapeutic medicine 2024 Jul;28(1):277
Experimental and therapeutic medicine 2024 Jul;28(1):277
Fibroblast growth factor 21 alleviates idiopathic pulmonary fibrosis by inhibiting PI3K-AKT-mTOR signaling and stimulating autophagy.
Qi J, Wu Y, Guo Z, Zhu S, Xiong J, Hu F, Liang X, Ye X
International journal of biological macromolecules 2024 Jul;273(Pt 1):132896
International journal of biological macromolecules 2024 Jul;273(Pt 1):132896
Hypericin-mediated photodynamic therapy inhibits metastasis and EMT of colorectal cancer cells by regulating RhoA-ROCK1 signaling pathway.
Hu J, Wen X, Song J
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2024 Jul;23(7):1361-1372
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2024 Jul;23(7):1361-1372
Grifolin Induces Cell Death of Human Lung Cancer A549 Cell Line via Inhibiting KRAS-Mediated Multiple Signaling Pathways.
Zhao XC, Ma RF, Liu H, Shan P, Bao J, Zhang H
Chemistry & biodiversity 2024 Jul;21(7):e202400792
Chemistry & biodiversity 2024 Jul;21(7):e202400792
Cryptochrome 2 Suppresses Epithelial-Mesenchymal Transition by Promoting Trophoblastic Ferroptosis in Unexplained Recurrent Spontaneous Abortion.
Li F, Guo L, Zhou M, Han L, Wu S, Wu L, Yang J
The American journal of pathology 2024 Jul;194(7):1197-1217
The American journal of pathology 2024 Jul;194(7):1197-1217
Triterpenoids with α-glucosidase inhibitory and cytotoxic activities from the fruits of Schisandra chinensis.
Sun P, Zhao XC, Ma ZY, Li ZH, Xu XL, Zhang H
Fitoterapia 2024 Jul;176:106029
Fitoterapia 2024 Jul;176:106029
LncRNA AC100826.1 regulated PLCB1 to promote progression in non-small cell lung cancer.
Dai S, Wang Q, Lyu Y, Chen Z, Liu X, Zhao G, Zhang H
Thoracic cancer 2024 Jul;15(19):1477-1489
Thoracic cancer 2024 Jul;15(19):1477-1489
LINC00460 promotes neuroblastoma tumorigenesis and cisplatin resistance by targeting miR-149-5p/DLL1 axis and activating Notch pathway in vitro and in vivo.
Xu Y, Qiu Z, Chen J, Huang L, Zhang J, Lin J
Drug delivery and translational research 2024 Jul;14(7):2003-2018
Drug delivery and translational research 2024 Jul;14(7):2003-2018
Baohuoside I chemosensitises breast cancer to paclitaxel by suppressing extracellular vesicle/CXCL1 signal released from apoptotic cells.
Wang S, Li J, Xu S, Wang N, Pan B, Yang B, Zheng Y, Zhang J, Peng F, Peng C, Wang Z
Journal of extracellular vesicles 2024 Jul;13(7):e12493
Journal of extracellular vesicles 2024 Jul;13(7):e12493
The EPRS-ATF4-COLI pathway axis is a potential target for anaplastic thyroid carcinoma therapy.
Mi L, Liu J, Zhang Y, Su A, Tang M, Xing Z, He T, Wei T, Li Z, Wu W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155670
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155670
Celastrol mediates CAV1 to attenuate pro-tumorigenic effects of senescent cells.
Zhang S, Zhu N, Shi YN, Zeng Q, Zhang CJ, Li HF, Qin L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155614
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155614
Mechanism of Nicotiflorin in San-Ye-Qing rhizome for anti-inflammatory effect in ulcerative colitis.
Ruan Y, Zhu X, Shen J, Chen H, Zhou G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155564
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155564
Targeting the PI3K/AKT/mTOR pathway offer a promising therapeutic strategy for cholangiocarcinoma patients with high doublecortin-like kinase 1 expression.
Liang Z, Ge Y, Li J, Bai Y, Xiao Z, Yan R, An G, Zhang D
Journal of cancer research and clinical oncology 2024 Jul 9;150(7):342
Journal of cancer research and clinical oncology 2024 Jul 9;150(7):342
SEC61 translocon gamma subunit is correlated with glycolytic activity, epithelial mesenchymal transition and the immune suppressive phenotype of lung adenocarcinoma.
Zhou C, Cui H, Yang Y, Chen L, Feng M, Gao Y, Li D, Li L, Chen X, Li X, Cao Y
Acta biochimica et biophysica Sinica 2024 Jul 8;56(12):1748-1760
Acta biochimica et biophysica Sinica 2024 Jul 8;56(12):1748-1760
New advances of NG2-expressing cell subset in marrow mesenchymal stem cells as novel therapeutic tools for liver fibrosis/cirrhosis.
Hu D, Lai J, Chen Q, Bai L
Stem cell research & therapy 2024 Jul 6;15(1):199
Stem cell research & therapy 2024 Jul 6;15(1):199
Echistatin/BYL-719 impedes epithelial-mesenchymal transition in pulmonary fibrosis induced by silica through modulation of the Integrin β1/ILK/PI3K signaling pathway.
Li H, Wang P, Hu M, Xu S, Li X, Xu D, Feng K, Zhou Q, Chang M, Yao S
International immunopharmacology 2024 Jul 30;136:112368
International immunopharmacology 2024 Jul 30;136:112368
Immunohistochemistry identifies E-cadherin, N-cadherin and focal adhesion kinase (FAK) as predictors of stage I non-small cell lung carcinoma spread through the air spaces (STAS), and the combinations as prognostic factors.
Meng Y, Wang Y, Liu L, Wu R, Zhang Q, Chen Z, Yao Y, Li X, Gong Y, Li H, Wang Z, Liu H
Translational lung cancer research 2024 Jul 30;13(7):1450-1462
Translational lung cancer research 2024 Jul 30;13(7):1450-1462
SIPA1 promotes epithelial-mesenchymal transition in colorectal cancer through STAT3 activation.
Li Y, Wang M, Jiang L, Jia J, Pan F, Li W, Wang B, Huang K, Luo J
Heliyon 2024 Jul 30;10(14):e34527
Heliyon 2024 Jul 30;10(14):e34527
Fabrication of heterocellular spheroids with controllable core-shell structure using inertial focusing effect for scaffold-free 3D cell culture models.
Tang T, Zhang P, Zhang Q, Man X, Xu Y
Biofabrication 2024 Jul 25;16(4)
Biofabrication 2024 Jul 25;16(4)
Construction of the pulmonary bio-adhesive delivery system of nintedanib nanocrystalline for effective treatment of pulmonary fibrosis.
Yun CX, Huan ML, Zhu X, Wan YH, Zou JB, Zhang BL
International journal of pharmaceutics 2024 Jul 20;660:124302
International journal of pharmaceutics 2024 Jul 20;660:124302
Alpha 1,3 N-Acetylgalactosaminyl Transferase (GTA) Impairs Invasion Potential of Trophoblast Cells in Preeclampsia.
Li Y, Wu H, Pei X, Liu S, Yan Q
International journal of molecular sciences 2024 Jul 2;25(13)
International journal of molecular sciences 2024 Jul 2;25(13)
Relaxin combined with transarterial chemoembolization achieved synergistic effects and inhibited liver cancer metastasis in a rabbit VX2 model.
Wang F, Zhu L, Xiong F, Chai B, Wang J, Zhou G, Cao Y, Zheng C
Journal of cancer research and clinical oncology 2024 Jul 2;150(7):333
Journal of cancer research and clinical oncology 2024 Jul 2;150(7):333
m6A-Mediated IRS1 Regulates the Development of Oral Squamous Cell Carcinoma through p53/Line-1 Signaling.
Xiao Y, Zhu X, Li Q, Wang Z, Zuo Q, Liu X, Tan J
Frontiers in bioscience (Landmark edition) 2024 Jul 19;29(7):257
Frontiers in bioscience (Landmark edition) 2024 Jul 19;29(7):257
Fasudil attenuates oxidative stress-induced partial epithelial-mesenchymal transition of tubular epithelial cells in hyperuricemic nephropathy via activating Nrf2.
Cao Y, Wang Y, Li W, Feng J, Chen Y, Chen R, Hu L, Wei J
European journal of pharmacology 2024 Jul 15;975:176640
European journal of pharmacology 2024 Jul 15;975:176640
DNA demethylase TET2-mediated reduction of HADHB expression contributes to cadmium-induced malignant progression of colorectal cancer.
Li L, Jiang M, Wang W, Cao X, Ma Q, Han J, Liu Z, Huang Y, Chen Y
Ecotoxicology and environmental safety 2024 Jul 15;280:116579
Ecotoxicology and environmental safety 2024 Jul 15;280:116579
A recombinant IL-1β vaccine attenuates bleomycin-induced pulmonary fibrosis in mice.
Li H, Li Q, Hao Z, Zhang L, Zheng X, Zhu L, Huo Y, Tian H, He L, Hao Z
Vaccine 2024 Jul 11;42(18):3774-3788
Vaccine 2024 Jul 11;42(18):3774-3788
Attenuated Salmonella typhimurium L forms suppress tumor growth and promote apoptosis in murine ovarian tumors.
Zhang Y, Tang Z, Shao Y, Yue X, Chu Y, Chen D
Scientific reports 2024 Jul 11;14(1):16045
Scientific reports 2024 Jul 11;14(1):16045
LINC01133 promotes pancreatic ductal adenocarcinoma epithelial-mesenchymal transition mediated by SPP1 through binding to Arp3.
Yang Y, Gong Y, Ding Y, Sun S, Bai R, Zhuo S, Zhang Z
Cell death & disease 2024 Jul 10;15(7):492
Cell death & disease 2024 Jul 10;15(7):492
LRP1 induces anti-PD-1 resistance by modulating the DLL4-NOTCH2-CCL2 axis and redirecting M2-like macrophage polarisation in bladder cancer.
Lin H, Fu L, Zhou X, Yu A, Chen Y, Liao W, Shu G, Zhang L, Tan L, Liang H, Wang Z, Deng Q, Wang J, Jin M, Chen Z, Wei J, Cao J, Chen W, Li X, Li P, Lu J, Luo J
Cancer letters 2024 Jul 1;593:216807
Cancer letters 2024 Jul 1;593:216807
SLC7A11 promotes EMT and metastasis in invasive pituitary neuroendocrine tumors by activating the PI3K/AKT signaling pathway.
Gui S, Yu W, Xie J, Peng L, Xiong Y, Song Z, Luo H, Xiao J, Yuan S, Cheng Z
Endocrine connections 2024 Jul 1;13(7)
Endocrine connections 2024 Jul 1;13(7)
Distinguished biomimetic dECM system facilitates early detection of metastatic breast cancer cells.
Weng B, Li M, Zhu W, Peng J, Mao X, Zheng Y, Zhang C, Pan S, Mao H, Zhao J
Bioengineering & translational medicine 2024 Jan;9(1):e10597
Bioengineering & translational medicine 2024 Jan;9(1):e10597
CHMP3 promotes the progression of hepatocellular carcinoma by inhibiting caspase‑1‑dependent pyroptosis.
Zheng Y, Yang S, Dai W, Wang J, Bi S, Zhang X, Zheng Z, Sun Y, Wu S, Kong J
International journal of oncology 2024 Jan;64(1)
International journal of oncology 2024 Jan;64(1)
PKMYT1 induced by YAP/TEAD1 gives rise to the progression and worse prognosis of bladder cancer.
Wang M, Zhang C, Ying Y, Hua M, Meng F, Wang Z, Liu A, Zeng S, Zhang Z, Xu C
Molecular carcinogenesis 2024 Jan;63(1):160-172
Molecular carcinogenesis 2024 Jan;63(1):160-172
Circ-SATB2 (hsa_circ_0008928) and miR-150-5p are regulators of TRIM66 in the regulation of NSCLC cell growth and metastasis of NSCLC cells via the ceRNA pathway.
Chen L, Zhou Y, Cheng H, Lu W, Cai M, Jiang K
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23615
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23615
MicroRNA-10a-5p-mediated downregulation of GATA6 inhibits tumor progression in ovarian cancer.
Gao F, Wu Q, Lu D
Human cell 2024 Jan;37(1):271-284
Human cell 2024 Jan;37(1):271-284
Nucleoporin 93, a new substrate of the E3 ubiquitin protein ligase HECTD1, promotes esophageal squamous cell carcinoma progression.
Zhang J, Xin Y, Ling X, Liang H, Zhang L, Fang C, Ma J
Human cell 2024 Jan;37(1):245-257
Human cell 2024 Jan;37(1):245-257
Spatiotemporally sequential delivery of biomimetic liposomes potentiates glioma chemotherapy.
Zhou M, Wu Y, Sun M, Qin Y, Zhao J, Qiu Z, Li C, Zhang Y, Xiong Y, Shen Y, Zou Z, Tu J, Shen W, Sun C
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:876-888
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:876-888
Hematoporphyrin derivative photodynamic therapy induces apoptosis and suppresses the migration of human esophageal squamous cell carcinoma cells by regulating the PI3K/AKT/mTOR signaling pathway.
Wei X, Ni J, Yuan L, Li X
Oncology letters 2024 Jan;27(1):17
Oncology letters 2024 Jan;27(1):17
Chitosan-based oral nanoparticles as an efficient platform for kidney-targeted drug delivery in the treatment of renal fibrosis.
Zhang Q, Li Y, Wang S, Gu D, Zhang C, Xu S, Fang X, Li C, Wu H, Xiong W
International journal of biological macromolecules 2024 Jan;256(Pt 1):128315
International journal of biological macromolecules 2024 Jan;256(Pt 1):128315
17β-Estradiol mediates TGFBR3/Smad2/3 signaling to attenuate the fibrosis of TGF-β1-induced bovine endometrial epithelial cells via GPER.
Fang Z, Wang Q, Duan H, Sheng X, Qi X, Xing K, Liu B, Chang D, Guo Y, Wang X, Xiao L
Journal of cellular physiology 2024 Jan;239(1):166-179
Journal of cellular physiology 2024 Jan;239(1):166-179
The homologous tumor-derived-exosomes loaded with miR-1270 selectively enhanced the suppression effect for colorectal cancer cells.
Jin Y, Sun L, Chen Y, Lu Y
Cancer medicine 2024 Jan;13(1):e6936
Cancer medicine 2024 Jan;13(1):e6936
Ligustilide prevents thymic immune senescence by regulating Thymosin β15-dependent spatial distribution of thymic epithelial cells.
Xu X, Tao N, Sun C, Hoffman RD, Shi D, Ying Y, Dong S, Gao J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155216
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155216
Hsa_circ_0013561 promotes progression of nasopharyngeal carcinoma by activating JAK2/STAT3 signaling pathway.
Kaisai T, Mantang Z, Tailei Y, Liying Z, Xiaoping C, Mingming J, Yi Z
Brazilian journal of otorhinolaryngology 2024 Jan-Feb;90(1):101362
Brazilian journal of otorhinolaryngology 2024 Jan-Feb;90(1):101362
Two-dimensional vascularized liver organoid on extracellular matrix with defined stiffness for modeling fibrotic and normal tissues.
Ma L, Yin L, Zhu H, Li J, Wang D
Journal of tissue engineering 2024 Jan-Dec;15:20417314241268344
Journal of tissue engineering 2024 Jan-Dec;15:20417314241268344
Hsa_circ_0081065 exacerbates IH-induced EndMT via regulating miR-665/HIF-1α signal axis and HIF-1α nuclear translocation.
Jiang S, Xing X, Hong M, Zhang X, Xu F, Zhang GH
Scientific reports 2024 Jan 9;14(1):904
Scientific reports 2024 Jan 9;14(1):904
Serine/threonine kinase 36 induced epithelial-mesenchymal transition promotes docetaxel resistance in prostate cancer.
He T, Li NX, Pan ZJ, Zou ZH, Chen JC, Yu SZ, Lv F, Xie QC, Zou J
Scientific reports 2024 Jan 6;14(1):729
Scientific reports 2024 Jan 6;14(1):729
TMCO1 regulates cell proliferation, metastasis and EMT signaling through CALR, promoting ovarian cancer progression and cisplatin resistance.
Sun G, Gong S, Lan S, He Y, Sun Y, Zhang Z
Cellular and molecular biology (Noisy-le-Grand, France) 2024 Jan 31;70(1):99-109
Cellular and molecular biology (Noisy-le-Grand, France) 2024 Jan 31;70(1):99-109
Lactate accumulation induced by Akt2-PDK1 signaling promotes pulmonary fibrosis.
Sun Z, Ji Z, He W, Duan R, Qu J, Yu G
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23426
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23426
Downregulation of Roundabout guidance receptor 2 suppresses hepatocellular carcinoma progression by interacting with Y-box binding protein 1.
Liu T, Zhai C, Tian B, Li C, Han S, Wang S, Xuan M, Liu D, Zhao Y, Zhao H, Yu W, Wang J
Scientific reports 2024 Jan 31;14(1):2588
Scientific reports 2024 Jan 31;14(1):2588
Sinensetin suppresses breast cancer cell progression via Wnt/β-catenin pathway inhibition.
Zhu S, Meng L, Wei P, Gu G, Duan K
Translational cancer research 2024 Jan 31;13(1):348-362
Translational cancer research 2024 Jan 31;13(1):348-362
Phthalides from the rhizome of Ligusticum chuanxiong Hort. attenuate diabetic nephropathy in mice.
Qi XY, Peng GC, Han QT, Yan J, Chen LZ, Wang T, Xu LT, Liu MJ, Xu ZP, Wang XN, Shen T
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117247
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117247
Quercetin inhibits mesothelial-mesenchymal transition and alleviates postoperative peritoneal adhesions by blocking the TGF-β1/PI3K/AKT pathway.
Li G, Ren Y, Li E, Deng K, Qu C, Zhang J, Zhang L, Wang X, Lian J, Zhou H, Wang Z, Shen T, Li X, Jiang Z
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117242
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117242
HIF-1A as a prognostic biomarker related to invasion, migration and immunosuppression of cervical cancer.
Li Z, Wei R, Yao S, Meng F, Kong L
Heliyon 2024 Jan 30;10(2):e24664
Heliyon 2024 Jan 30;10(2):e24664
Transcription factor FOXP4 inversely governs tumor suppressor genes and contributes to thyroid cancer progression.
Zhou T, Ma N, Zhang YL, Chen XH, Luo X, Zhang M, Gao QJ, Zhao DW
Heliyon 2024 Jan 30;10(2):e23875
Heliyon 2024 Jan 30;10(2):e23875
Dexmedetomidine ameliorates high glucose-induced epithelial-mesenchymal transformation in HK-2 cells through the Cdk5/Drp1/ROS pathway.
Wang F, Xu W, Liu X, Zhang J
Acta biochimica et biophysica Sinica 2024 Jan 25;56(1):71-81
Acta biochimica et biophysica Sinica 2024 Jan 25;56(1):71-81
Nicotinamide mononucleotide attenuates airway epithelial barrier dysfunction via inhibiting SIRT3 SUMOylation in asthma.
Liang J, Zhou C, Zhang C, Liang S, Zhou Z, Zhou Z, Wu C, Zhao H, Meng X, Zou F, Yu C, Cai S
International immunopharmacology 2024 Jan 25;127:111328
International immunopharmacology 2024 Jan 25;127:111328
FBXO28 promotes cell proliferation, migration and invasion via upregulation of the TGF-beta1/SMAD2/3 signaling pathway in ovarian cancer.
Song G, Sun Z, Chu M, Zhang Z, Chen J, Wang Z, Zhu X
BMC cancer 2024 Jan 24;24(1):122
BMC cancer 2024 Jan 24;24(1):122
Circular RNA DNAH14 molecular mechanism in an experimental model of hepatocellular carcinoma treated with Cobalt chloride to mimic the hypoxia-like response of transcatheter arterial chemoembolization.
Liao Q, Xia W, Chen J, Wang K, Xiao E
Scientific reports 2024 Jan 23;14(1):1992
Scientific reports 2024 Jan 23;14(1):1992
ERH gene knockdown inhibits the proliferation and migration of ARPE-19 cells through MCM complex and EMT process.
Li M, Zhang Z, Guan L, Ji S, Lu P
Gene 2024 Jan 20;892:147855
Gene 2024 Jan 20;892:147855
A Platform for Testing the Biocompatibility of Implants: Silicone Induces a Proinflammatory Response in a 3D Skin Equivalent.
Nuwayhid R, Schulz T, Siemers F, Schreiter J, Kobbe P, Hofmann G, Langer S, Kurow O
Biomedicines 2024 Jan 19;12(1)
Biomedicines 2024 Jan 19;12(1)
DDX60 Promotes Migration and Invasion of Head and Neck Squamous Cell Carcinoma Cell through the NF-κB/IFI27 Signaling Pathway.
Han Y, Gao J, Liu L
Frontiers in bioscience (Landmark edition) 2024 Jan 17;29(1):14
Frontiers in bioscience (Landmark edition) 2024 Jan 17;29(1):14
Thymosin β4 Regulates the Differentiation of Thymocytes by Controlling the Cytoskeletal Rearrangement and Mitochondrial Transfer of Thymus Epithelial Cells.
Ying Y, Tao N, Zhang F, Wen X, Zhou M, Gao J
International journal of molecular sciences 2024 Jan 16;25(2)
International journal of molecular sciences 2024 Jan 16;25(2)
A transcriptome based molecular classification scheme for cholangiocarcinoma and subtype-derived prognostic biomarker.
Fan Z, Zou X, Wang G, Liu Y, Jiang Y, Wang H, Zhang P, Wei F, Du X, Wang M, Sun X, Ji B, Hu X, Chen L, Zhou P, Wang D, Bai J, Xiao X, Zuo L, Xia X, Yi X, Lv G
Nature communications 2024 Jan 11;15(1):484
Nature communications 2024 Jan 11;15(1):484
Rehmannia glutinosa Libosch and Cornus officinalis Sieb herb couple ameliorates renal interstitial fibrosis in CKD rats by inhibiting the TGF-β1/MAPK signaling pathway.
Zhu JH, Wang L, Ma ZX, Duan JA, Tao JH
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117039
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117039
Tumor-associated macrophage-derived exosomal miR-513b-5p is a target of jianpi yangzheng decoction for inhibiting gastric cancer.
Zhang R, Chen X, Miao C, Chen Y, Li Y, Shen J, Yuan M, Chen M, Cheng J, Liu S, Sun Q, Wu J
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117013
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117013
Panax notoginseng saponin alleviates pulmonary fibrosis in rats by modulating the renin-angiotensin system.
Li H, Wang YG, Chen TF, Gao YH, Song L, Yang YF, Gao Y, Huo W, Zhang GP
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):116979
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):116979
Metabolomics study reveals increased deoxycholic acid contributes to deoxynivalenol-mediated intestinal barrier injury.
He X, Zhou HX, Fu X, Ni KD, Lin AZ, Zhang LT, Yin HH, Jiang Q, Zhou X, Meng YW, Liu JY
Life sciences 2024 Jan 1;336:122302
Life sciences 2024 Jan 1;336:122302
The Microbial Tryptophan Metabolite Contributes to the Remission of Salmonella typhimurium Infection in Mice.
Li Y, Li J, Jia D, Gao S, Guo Y, Liu J, Wang J, Guan G, Luo J, Yin H, Xiao S, Li Y
Journal of immunology (Baltimore, Md. : 1950) 2024 Jan 1;212(1):57-68
Journal of immunology (Baltimore, Md. : 1950) 2024 Jan 1;212(1):57-68
Identification of MDK as a Hypoxia- and Epithelial-Mesenchymal Transition-Related Gene Biomarker of Glioblastoma Based on a Novel Risk Model and In Vitro Experiments.
Xia M, Tong S, Gao L
Biomedicines 2024 Jan 1;12(1)
Biomedicines 2024 Jan 1;12(1)
Cold atmospheric plasma sensitizes head and neck cancer to chemotherapy and immune checkpoint blockade therapy.
Wang Y, Mang X, Li D, Wang Z, Chen Y, Cai Z, Tan F
Redox biology 2024 Feb;69:102991
Redox biology 2024 Feb;69:102991
Melatonin decreases GSDME mediated mesothelial cell pyroptosis and prevents peritoneal fibrosis and ultrafiltration failure.
Ruan H, Li X, Zhou L, Zheng Z, Hua R, Wang X, Wang Y, Fan Y, Guo S, Wang L, Ur Rahman S, Wang Z, Wei Y, Yu S, Zhang R, Cheng Q, Sheng J, Li X, Liu X, Yuan R, Zhang X, Chen L, Xu G, Guan Y, Nie J, Qin H, Zheng F
Science China. Life sciences 2024 Feb;67(2):360-378
Science China. Life sciences 2024 Feb;67(2):360-378
Circular RNA Dipeptidyl Peptidase 4 (circDPP4) Stimulates the Expression of Glutamate Dehydrogenase 1 to Contribute to the Malignant Phenotypes of Prostate Cancer by Sponging miR-497-5p.
Pei L, Song X, Liang X, Li M, Zhang A, Tan X
Molecular biotechnology 2024 Feb;66(2):241-253
Molecular biotechnology 2024 Feb;66(2):241-253
NMI promotes tumor progression and gemcitabine resistance in pancreatic cancer via STAT3-IFIT3 axis.
Hu H, Li B, Chen H, Fan G, Ye Z, Ji S, Yu X, Xu X, Qin Y
Molecular carcinogenesis 2024 Feb;63(2):195-208
Molecular carcinogenesis 2024 Feb;63(2):195-208
Spindle and kinetochore-related complex subunit 3 has a protumour function in osteosarcoma by activating the Notch pathway.
Liang G, Duan C, He J, Shi L
Toxicology and applied pharmacology 2024 Feb;483:116826
Toxicology and applied pharmacology 2024 Feb;483:116826
Exosomal circ_0037104 derived from Hu-MSCs inhibits cholangiocarcinoma progression by sponging miR-620 and targeting AFAP1.
Yuan Z, Xiong B, Liu L, Lu Y, Liu Y, Wang G, Qian Y, Diao B, Tu M
Journal of biochemical and molecular toxicology 2024 Feb;38(2):e23656
Journal of biochemical and molecular toxicology 2024 Feb;38(2):e23656
Icariside II prevents kidney fibrosis development in chronic kidney disease by promoting fatty acid oxidation.
Wang M, Wang J, Wang L, Feng X, Qian Y, Ye C, Wang C
Phytotherapy research : PTR 2024 Feb;38(2):839-855
Phytotherapy research : PTR 2024 Feb;38(2):839-855
Serabelisib regulates GSDMD-mediated pyroptosis, apoptosis and migration of hepatoma cells via the PI3K/Akt/E-cadherin signaling pathway.
Li M, Huang Z, Zhou Y
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2024 Feb;33(2):171-181
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2024 Feb;33(2):171-181
Promoting effect and immunologic role of secretogranin II on bladder cancer progression via regulating MAPK and NF-κB pathways.
Zhou J, Dong C, Tan J, Wang G, Li Z, Li S, He Z
Apoptosis : an international journal on programmed cell death 2024 Feb;29(1-2):121-141
Apoptosis : an international journal on programmed cell death 2024 Feb;29(1-2):121-141
Exosome-delivered miR-410-3p reverses epithelial-mesenchymal transition, migration and invasion of trophoblasts in spontaneous abortion.
Chen ZY, Li Z, Zong Y, Xia B, Luo SP, Deng GP, Gao J
Journal of cellular and molecular medicine 2024 Feb;28(3):e18097
Journal of cellular and molecular medicine 2024 Feb;28(3):e18097
Bone morphogenetic protein 4 thermosensitive hydrogel inhibits corneal neovascularization by repairing corneal epithelial apical junctional complexes.
Nan W, Shen S, Yang Y, Wu M, He Y, Zhang R, Cui X, Zhang Y
Materials today. Bio 2024 Feb;24:100944
Materials today. Bio 2024 Feb;24:100944
GK921, a transglutaminase inhibitor, strengthens the antitumor effect of cisplatin on pancreatic cancer cells by inhibiting epithelial-to-mesenchymal transition.
Li M, Wang X, Chen X, Hong J, Du Y, Song D
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166925
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166925
Downregulation of TET2 Contributes to Nasal Polypogenesis Through Hypoxia-Inducible Factor 1α-Mediated Epithelial-to-Mesenchymal Transition.
Liu K, Xu Y
Clinical and experimental otorhinolaryngology 2024 Feb;17(1):64-77
Clinical and experimental otorhinolaryngology 2024 Feb;17(1):64-77
GIMAP7 inhibits epithelial-mesenchymal transition and glycolysis in lung adenocarcinoma cells via regulating the Smo/AMPK signaling pathway.
Cui L, Shen Y, Duan S, Ding Q, Wang Y, Yang W, Chen Y
Thoracic cancer 2024 Feb;15(4):286-298
Thoracic cancer 2024 Feb;15(4):286-298
Ginsenoside Rk3 modulates gut microbiota and regulates immune response of group 3 innate lymphoid cells to against colorectal tumorigenesis.
Bai X, Fu R, Liu Y, Deng J, Fei Q, Duan Z, Zhu C, Fan D
Journal of pharmaceutical analysis 2024 Feb;14(2):259-275
Journal of pharmaceutical analysis 2024 Feb;14(2):259-275
Tumor suppressor miR-361-3p inhibits prostate cancer progression through Gli1 and AKT/mTOR signaling pathway.
Wang S, Huang X, Zhang G, Chen Z, Guan H, Zhou W
Cellular signalling 2024 Feb;114:110998
Cellular signalling 2024 Feb;114:110998
MPDZ is associated with immune infiltration and regulates migration and invasion by switching YAP1 phosphorylation in colorectal cancer.
Chen Z, Ba Y, Zhao N, Dang Q, Xu H, Weng S, Zhang Y, Liu S, Zuo A, Han X, Liu Z
Cellular signalling 2024 Feb;114:110967
Cellular signalling 2024 Feb;114:110967
Luteolin blocks the ROS/PI3K/AKT pathway to inhibit mesothelial-mesenchymal transition and reduce abdominal adhesions.
Ren Y, Li G, Li E, Deng K, Lian J, Gao Q, Wang H, Wang X, Wang Z, Shen T, Jiang Z, Li X, Qiu G
European journal of pharmacology 2024 Feb 5;964:176272
European journal of pharmacology 2024 Feb 5;964:176272
Interaction between Wnt/β-catenin signaling pathway and EMT pathway mediates the mechanism of sunitinib resistance in renal cell carcinoma.
Cai F, Li J, Zhang Y, Huang S, Liu W, Zhuo W, Qiu C
BMC cancer 2024 Feb 5;24(1):175
BMC cancer 2024 Feb 5;24(1):175
SMG9 is a novel prognostic-related biomarker in glioma correlating with ferroptosis and immune infiltrates.
Dai Y, Zhang H, Feng S, Guo C, Tian W, Sun Y, Zhang Y
Heliyon 2024 Feb 29;10(4):e25716
Heliyon 2024 Feb 29;10(4):e25716
Bufei Yishen formula protects the airway epithelial barrier and ameliorates COPD by enhancing autophagy through the Sirt1/AMPK/Foxo3 signaling pathway.
Jia L, Liu X, Liu X, Guan Q, Tian Y, Li J, Zhao P
Chinese medicine 2024 Feb 28;19(1):32
Chinese medicine 2024 Feb 28;19(1):32
SLC25A17 inhibits autophagy to promote triple-negative breast cancer tumorigenesis by ROS-mediated JAK2/STAT3 signaling pathway.
Zhou H, Li J, He Y, Xia X, Liu J, Xiong H
Cancer cell international 2024 Feb 24;24(1):85
Cancer cell international 2024 Feb 24;24(1):85
The miR-1290/OGN axis in ovarian cancer-associated fibroblasts modulates cancer cell proliferation and invasion.
Jiang B, Xiao S, Zhang S, Xiao F
Journal of ovarian research 2024 Feb 24;17(1):52
Journal of ovarian research 2024 Feb 24;17(1):52
Novel prognostic marker TGFBI affects the migration and invasion function of ovarian cancer cells and activates the integrin αvβ3-PI3K-Akt signaling pathway.
Wang H, Xu YH, Guo Y
Journal of ovarian research 2024 Feb 23;17(1):50
Journal of ovarian research 2024 Feb 23;17(1):50
m6A-methylated KCTD21-AS1 regulates macrophage phagocytosis through CD47 and cell autophagy through TIPR.
Liang DM, Li YJ, Zhang JX, Shen HH, Wu CX, Xie N, Liang Y, Li YM, Xue JN, Sun HF, Wang Q, Yang J, Li XH, Wang PY, Xie SY
Communications biology 2024 Feb 21;7(1):215
Communications biology 2024 Feb 21;7(1):215
LINC02561 promotes metastasis in HCC via HIF1-α/NDRG1/UPF1 axis.
Li SN, Li MX, Guo WW, Zhang LR, Ding YH, Wu XJ
Gene 2024 Feb 20;896:148033
Gene 2024 Feb 20;896:148033
miR-34c-5p inhibited fibroblast proliferation, differentiation and epithelial-mesenchymal transition in benign airway stenosis via MDMX/p53 pathway.
Wei J, Chen Y, Feng T, Wei Y, Yang C, Zhang C, Li W, Liu G
Functional & integrative genomics 2024 Feb 20;24(2):37
Functional & integrative genomics 2024 Feb 20;24(2):37
Crosstalk between KDEL receptor and EGF receptor mediates cell proliferation and migration via STAT3 signaling.
Jia J, Zhu L, Yue X, Tang S, Jing S, Tan C, Du Y, Gao J, Lee I, Qian Y
Cell communication and signaling : CCS 2024 Feb 20;22(1):140
Cell communication and signaling : CCS 2024 Feb 20;22(1):140
LncRNA RPARP-AS1 promotes the progression of osteosarcoma cells through regulating lipid metabolism.
Cai F, Liu L, Bo Y, Yan W, Tao X, Peng Y, Zhang Z, Liao Q, Yi Y
BMC cancer 2024 Feb 2;24(1):166
BMC cancer 2024 Feb 2;24(1):166
The clustering status of detached gastric cancer cells inhibits anoikis-induced ferroptosis to promote metastatic colonization.
Sun J, Li J, Pantopoulos K, Liu Y, He Y, Kang W, Ye X
Cancer cell international 2024 Feb 18;24(1):77
Cancer cell international 2024 Feb 18;24(1):77
Investigating HMGB1 as a potential serum biomarker for early diabetic nephropathy monitoring by quantitative proteomics.
Peng R, Zuo S, Li X, Huang Y, Chen S, Zou X, Long H, Chen M, Yang Y, Yuan H, Zhao Q, Guo B, Liu L
iScience 2024 Feb 16;27(2):108834
iScience 2024 Feb 16;27(2):108834
YTHDF2-mediated circYAP1 drives immune escape and cancer progression through activating YAP1/TCF4-PD-L1 axis.
Chen Z, Wang W, Hu S, Sun H, Chen C, Zhang Z, Sun X, Jia B, Hu J, Wang C, Liu Y, Sun Z
iScience 2024 Feb 16;27(2):108779
iScience 2024 Feb 16;27(2):108779
Calcitriol promotes M2 polarization of tumor-associated macrophages in 4T1 mouse mammary gland cancer via the induction of proinflammatory cytokines.
Stachowicz-Suhs M, Łabędź N, Anisiewicz A, Banach J, Kłopotowska D, Milczarek M, Piotrowska A, Dzięgiel P, Maciejczyk A, Matkowski R, Wietrzyk J
Scientific reports 2024 Feb 15;14(1):3778
Scientific reports 2024 Feb 15;14(1):3778
ZNF460-mediated circRPPH1 promotes TNBC progression through ITGA5-induced FAK/PI3K/AKT activation in a ceRNA manner.
Zhang C, Yu Z, Yang S, Liu Y, Song J, Mao J, Li M, Zhao Y
Molecular cancer 2024 Feb 14;23(1):33
Molecular cancer 2024 Feb 14;23(1):33
Icariin Regulates EMT and Stem Cell-Like Character in Breast Cancer through Modulating lncRNA NEAT1/TGFβ/SMAD2 Signaling Pathway.
Song B, Wei F, Peng J, Wei X, Liu M, Nie Z, Ma Y, Peng T
Biological & pharmaceutical bulletin 2024 Feb 10;47(2):399-410
Biological & pharmaceutical bulletin 2024 Feb 10;47(2):399-410
Bromodomain containing 4 inhibition combats gastric precancerous lesions via modulating macrophage polarization.
Zhu L, Cai Q, Li G, Zou X
Tissue & cell 2024 Dec;91:102580
Tissue & cell 2024 Dec;91:102580
Up-regulation of long non-coding RNA H19 ameliorates renal tubulointerstitial fibrosis by reducing lipid deposition and inflammatory response through regulation of the microRNA-130a-3p/long-chain acyl-CoA synthetase 1 axis.
Jiang Y, Ma F, Wang J, Chen X, Xue L, Chen X, Hu J
Non-coding RNA research 2024 Dec;9(4):1120-1132
Non-coding RNA research 2024 Dec;9(4):1120-1132
Therapeutic potential of Lacticaseibacillus rhamnosus grx10 and its derived postbiotic through gut microbiota and MAPK/MLCK/MLC pathway-mediated intestinal barrier repairment in ulcerative colitis.
Ye H, Liu X, Guan K, Ma Y, Liu R, Liu Y, Lv X, Wang R, Li Q
Journal of food science 2024 Dec;89(12):10035-10052
Journal of food science 2024 Dec;89(12):10035-10052
RSL3 sensitizes glioma cells to ionizing radiation by suppressing TGM2-dependent DNA damage repair and epithelial-mesenchymal transition.
Wang X, Shi W, Li M, Xin Y, Jiang X
Redox biology 2024 Dec;78:103438
Redox biology 2024 Dec;78:103438
CircRNA ITCH Inhibits Epithelial-Mesenchymal Transformation and Promotes Apoptosis in Papillary Thyroid Carcinoma via miR-106a-5p/JAZF1 Axis.
Chen Y, Lian Z, Zhang G, Lin Y, Zhang G, Liu W, Gao J, Zheng Z
Biochemical genetics 2024 Dec;62(6):4755-4769
Biochemical genetics 2024 Dec;62(6):4755-4769
Tabersonine enhances cisplatin sensitivity by modulating Aurora kinase A and suppressing epithelial-mesenchymal transition in triple-negative breast cancer.
Chen X, Yan Y, Liu Y, Yi Q, Xu Z
Pharmaceutical biology 2024 Dec;62(1):394-403
Pharmaceutical biology 2024 Dec;62(1):394-403
Unraveling the mechanisms of RECQL4-mediated cervical cancer progression through the PI3K/AKT pathway.
Huo W, Huang Y, Tian B, Chen X, Lu J, Huang X, Wu M, Yu J, Chen D, Wang R
Translational oncology 2024 Dec;50:102146
Translational oncology 2024 Dec;50:102146
Establishment and optimization of a novel mouse model of hyperuricemic nephropathy.
Wang J, Chen R, Wu K, Mo J, Li M, Chen Z, Wang G, Zhou P, Lan T
Renal failure 2024 Dec;46(2):2427181
Renal failure 2024 Dec;46(2):2427181
TXNIP deficiency attenuates renal fibrosis by modulating mTORC1/TFEB-mediated autophagy in diabetic kidney disease.
Du Y, Wu M, Song S, Bian Y, Shi Y
Renal failure 2024 Dec;46(1):2338933
Renal failure 2024 Dec;46(1):2338933
Adaptor protein CEMIP reduces the chemosensitivity of small cell lung cancer via activation of an SRC-YAP oncogenic module.
Shen XJ, Wei HL, Mo XC, Mo XX, Li L, He JC, Wei XY, Qin XJ, Xing SP, Luo Z, Chen ZQ, Yang J
Acta pharmacologica Sinica 2024 Dec;45(12):2657-2671
Acta pharmacologica Sinica 2024 Dec;45(12):2657-2671
M6A RNA Methylation-Mediated TUG1 Stability Maintains Mitochondrial Homeostasis during Kidney Aging by Epigenetically Regulating PGC1-α Expression.
Zhu Y, Yang B, Chen S, Chen G, Zeng X, Min H, Xu L
Antioxidants & redox signaling 2024 Dec;41(16-18):993-1013
Antioxidants & redox signaling 2024 Dec;41(16-18):993-1013
Mediation of circ_0007142 on miR-128-3p/S100A14 pathway to stimulate the progression of cervical cancer.
Feng Q, Shen Z, Wang F, Shi C
Naunyn-Schmiedeberg's archives of pharmacology 2024 Dec;397(12):9919-9933
Naunyn-Schmiedeberg's archives of pharmacology 2024 Dec;397(12):9919-9933
Increased UBD Is a Potential Diagnostic and Prognostic Biomarker in Glioma.
Wu T, Du M, Zeng L, Wang H, Li X
Environmental toxicology 2024 Dec;39(12):5250-5263
Environmental toxicology 2024 Dec;39(12):5250-5263
Dihydroartemisinin enhances the anti-tumour effect of photodynamic therapy by targeting PKM2-mediated glycolysis in oesophageal cancer cell.
Jin M, Shi L, Wang L, Zhang D, Li Y
Journal of enzyme inhibition and medicinal chemistry 2024 Dec;39(1):2296695
Journal of enzyme inhibition and medicinal chemistry 2024 Dec;39(1):2296695
Baicalein inhibits cell proliferation and induces apoptosis in brain glioma cells by downregulating the LGR4-EGFR pathway.
Zhang X, Shao X, Bao Q, He L, Qi X
Cancer gene therapy 2024 Dec;31(12):1856-1867
Cancer gene therapy 2024 Dec;31(12):1856-1867
PH-sensitive adriamycin hydrochloride and oxaliplatin dual-loaded microspheres synergistically enhance local injections effect of hepatocellular carcinoma.
Weng J, Wu S, Pan Y, Lai Y, Zhu J, Jin W, Lu D, Chen Y, Yu Z, Zan X, Xia J
Materials today. Bio 2024 Dec;29:101311
Materials today. Bio 2024 Dec;29:101311
AOPPs induces EMT and fibrosis by activating oxidative stress through ERK/p38 MAPK signaling pathway in endometriosis.
Luo X, Wen S, Zeng J, Liu J, Ye W, Wu J, Huang S, Xie W, Wen H, Sun Y, Cai J, Mo D, Lin Q, Chen M, Xia S, Song Y
Reproductive biology 2024 Dec;24(4):100950
Reproductive biology 2024 Dec;24(4):100950
Activation of ferritin light chain (FTL) by transcription factor salmonella pathogenicity island 1 modulates glycolysis to drive metastasis of ovarian cancer cells.
Li C, Yang Y, Lin Y, Lian Y, Pan D, Lin L, Li L
Expert review of anticancer therapy 2024 Dec;24(12):1271-1282
Expert review of anticancer therapy 2024 Dec;24(12):1271-1282
Critical role of apoptosis in MeCP2-mediated epithelial-mesenchymal transition of ARPE-19 cells.
Zhang Y, Wu F, Guo S, Yin R, Yuan M, Li X, Zhao X, Li X
Journal of cellular physiology 2024 Dec;239(12):e31429
Journal of cellular physiology 2024 Dec;239(12):e31429
Quercetin inhibits malignant progression of high metastatic advanced colon cancer in hypoxia via suppressing ROS and PI3K/AKT pathway.
Shang P, Yang J, Shao L, Sun C, Ji J, Wang X, Zheng Z, Guo X
Pharmaceutical science advances 2024 Dec;2:100057
Pharmaceutical science advances 2024 Dec;2:100057
Sec13 promotes glycolysis by inhibiting Ubqln1 mediated Pgm1 ubiquitination in ALI.
Wu D, Zhang H, Li F, Liu S, Wang Y, Zhang Z, Wang J, Wu Q
Biochimica et biophysica acta. Molecular basis of disease 2024 Dec;1870(8):167475
Biochimica et biophysica acta. Molecular basis of disease 2024 Dec;1870(8):167475
Hypoxia-driven heterogeneous expression of α5 integrin in glioblastoma stem cells is linked to HIF-2α.
Messé M, Bernhard C, Foppolo S, Thomas L, Marchand P, Herold-Mende C, Idbaih A, Kessler H, Etienne-Selloum N, Ochoa C, Tambar UK, Elati M, Laquerriere P, Entz-Werle N, Martin S, Reita D, Dontenwill M
Biochimica et biophysica acta. Molecular basis of disease 2024 Dec;1870(8):167471
Biochimica et biophysica acta. Molecular basis of disease 2024 Dec;1870(8):167471
Sodium cromoglycate exerts anti-pulmonary fibrosis effects by targeting the Keap1 protein to activate Nrf2 signaling.
Liu X, Huang Y, Zhao X, Guan Y, Li Y, Yuan L, Wang C, Ma C, Ma E
Bioorganic chemistry 2024 Dec;153:107961
Bioorganic chemistry 2024 Dec;153:107961
Suyin Detoxification Granule alleviates trimethylamine N-oxide-induced tubular ferroptosis and renal fibrosis to prevent chronic kidney disease progression.
Ge H, Wei Y, Zhang W, Yong C, Chen Y, Zhou E
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156195
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156195
Jia Wei Qingxin Lotus Seed Drink ameliorates epithelial mesenchymal transition injury in diabetic kidney disease via inhibition of JMJD1C/SP1/ZEB1 signaling pathway.
Xie J, Lin H, Jin F, Luo Y, Yang P, Song J, Yao W, Lin W, Yuan D, Zuo A, Sun J, Wang M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156142
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156142
Corynoxine exerts the anti-tumor effect on esophageal squamous cell carcinoma principally via the EZH2-DUSP5-ERK1/2-mediated cell growth inhibition.
Huang G, Xu J, Li Y, Song L, Wen C, Ruan Q, Wen Z, Qi J, Deng J, Liu Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156103
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156103
Targeting and degradation of OTUB1 by Erianin for antimetastasis in esophageal squamous cell carcinoma.
Zhu Y, Kang N, Zhang L, Tao J, Xue W, Li H, Li Y, Zheng X, He W, Ma J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:155969
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:155969
FAM3C Regulates Glioma Cell Proliferation, Invasion, Apoptosis, and Epithelial Mesenchymal Transition via the Notch Pathway.
Xia X, Wang Z, Song L, Cheng Y, Xiong P, Li S
Cancer medicine 2024 Dec;13(23):e70412
Cancer medicine 2024 Dec;13(23):e70412
Quercetin prevents the USP22-Snail1 signaling pathway to ameliorate diabetic tubulointerstitial fibrosis.
Zhao X, Wang S, He X, Wei W, Huang K
Food & function 2024 Dec 9;15(24):11990-12006
Food & function 2024 Dec 9;15(24):11990-12006
Mechanistic study of quercetin in the treatment of hepatocellular carcinoma with diabetes via MEK/ERK pathway.
Lin F, Zhou W, Yuan X, Liu S, He Z
International immunopharmacology 2024 Dec 5;142(Pt B):113194
International immunopharmacology 2024 Dec 5;142(Pt B):113194
Activin A inhibits the migration of human lung adenocarcinoma A549 cells induced by EGF.
Zhang F, Cui X, Yang K, Guo R, Zhu L, Zhao W, Liu Z, Liu B
International immunopharmacology 2024 Dec 5;142(Pt B):113170
International immunopharmacology 2024 Dec 5;142(Pt B):113170
Bone morphogenetic protein 4 inhibits corneal neovascularization by blocking NETs-induced disruption to corneal epithelial barrier.
Shen S, Nan W, Zhang W, Wu H, Zhang Y
International immunopharmacology 2024 Dec 5;142(Pt A):113023
International immunopharmacology 2024 Dec 5;142(Pt A):113023
Serine related gene CCT6A promotes metastasis of hepatocellular carcinoma via interacting with RPS3.
Cui H, Jiang L, Zhou Y, Zhou Y, Li F, Zhang Z
Functional & integrative genomics 2024 Dec 4;24(6):225
Functional & integrative genomics 2024 Dec 4;24(6):225
Tripartite motif-containing protein 50 suppresses triple-negative breast cancer progression by regulating the epithelial-mesenchymal transition.
Chen D, Jiang J, Zhang W, Li X, Ge Q, Liu X, Li X
Cancer biology & therapy 2024 Dec 31;25(1):2427410
Cancer biology & therapy 2024 Dec 31;25(1):2427410
MiR-135b-5p promotes cetuximab resistance in colorectal cancer by regulating FOXN3.
Peng C, Li X, Yao Y, Nie Y, Fan L, Zhu C
Cancer biology & therapy 2024 Dec 31;25(1):2373497
Cancer biology & therapy 2024 Dec 31;25(1):2373497
RND1 inhibits epithelial-mesenchymal transition and temozolomide resistance of glioblastoma via AKT/GSK3-β pathway.
Sun Q, Xu J, Yuan F, Liu Y, Chen Q, Guo L, Dong H, Liu B
Cancer biology & therapy 2024 Dec 31;25(1):2321770
Cancer biology & therapy 2024 Dec 31;25(1):2321770
DNMT1-driven methylation of RORA facilitates esophageal squamous cell carcinoma progression under hypoxia through SLC2A3.
Yao W, Shang L, Wang Y, Xu L, Bai Y, Feng M, Jia X, Wu S
Journal of translational medicine 2024 Dec 31;22(1):1167
Journal of translational medicine 2024 Dec 31;22(1):1167
Macropinocytosis inhibits alkaliptosis in pancreatic cancer cells through fatty acid uptake.
Chen F, Tang H, Lin J, Xiang L, Lu Y, Kang R, Tang D, Liu J
Carcinogenesis 2024 Dec 30;45(12):953-964
Carcinogenesis 2024 Dec 30;45(12):953-964
Chromatin licensing and DNA replication factor 1 as a potential prognostic and diagnostic biomarker for gastric cancer.
Wang S, Cui M, Zhou N, Tong M, Wu S, Li H, Cao Z
Scientific reports 2024 Dec 28;14(1):31000
Scientific reports 2024 Dec 28;14(1):31000
GPR37-enhanced ubiquitination of ATP1A1 inhibits tumor progression and radiation resistance in esophageal squamous cell carcinoma.
Hu J, Meng F, Lv L, Hong F, He Q, Zhu Q, Tian T, Chang N, Zhang S, Yi Q, Qian L
Cell death & disease 2024 Dec 27;15(12):933
Cell death & disease 2024 Dec 27;15(12):933
CTSG is a prognostic marker involved in immune infiltration and inhibits tumor progression though the MAPK signaling pathway in non-small cell lung cancer.
Dai Q, Yao X, Zhang Y, Chai Q, Feng X, Zhu H, Zhao L
Journal of cancer research and clinical oncology 2024 Dec 26;151(1):21
Journal of cancer research and clinical oncology 2024 Dec 26;151(1):21
METTL14 downregulates GLUT9 through m6A methylation and attenuates hyperuricemia-induced fibrosis in mouse renal tubular epithelial cells.
Yang J, Jiang T, Lu X, Li X, Zhou X, Guo X, Ma C, Xie X, Li D, Yu S, An J, Zhao B, Li H
International immunopharmacology 2024 Dec 25;143(Pt 1):113308
International immunopharmacology 2024 Dec 25;143(Pt 1):113308
Identification of UNC5B as a novel aggressive biomarker for osteosarcoma based on basement membrane genes.
Pan R, Zhang Y, Cheng Y, Wu Z, Liu J, Chen Z, Wang J, Zhang X, Wang H, Feng S, Zheng X
Gene 2024 Dec 20;930:148871
Gene 2024 Dec 20;930:148871
ANGPTL4 mediated mesothelial-mesenchymal transition in pulmonary fibrosis: a potential therapeutic target.
Xia Y, Zhou F, Hui H, Dai L, Ouyang S
Journal of translational medicine 2024 Dec 20;22(1):1114
Journal of translational medicine 2024 Dec 20;22(1):1114
Exosomes containing circSCP2 in colorectal cancer promote metastasis via sponging miR-92a-1-5p and interacting with PTBP1 to stabilize IGF2BP1.
Meng Q, Xiang H, Wang Y, Hu K, Luo X, Wang J, Chen E, Zhang W, Chen J, Chen X, Wang H, Ju Z, Song Z
Biology direct 2024 Dec 20;19(1):130
Biology direct 2024 Dec 20;19(1):130
Roles of gut microbiome-associated metabolites in pulmonary fibrosis by integrated analysis.
Li J, Wu W, Kong X, Yang X, Li K, Jiang Z, Zhang C, Zou J, Liang Y
NPJ biofilms and microbiomes 2024 Dec 19;10(1):154
NPJ biofilms and microbiomes 2024 Dec 19;10(1):154
Machine learning-based prognostic model of lactylation-related genes for predicting prognosis and immune infiltration in patients with lung adenocarcinoma.
Gao M, Wang M, Zhou S, Hou J, He W, Shu Y, Wang X
Cancer cell international 2024 Dec 18;24(1):400
Cancer cell international 2024 Dec 18;24(1):400
miR-3191 promotes the proliferation and metastasis of hepatocellular carcinoma via regulating PAK6.
Xie A, Wang H, Huang J, Sun M, Chen L
Infectious agents and cancer 2024 Dec 18;19(1):64
Infectious agents and cancer 2024 Dec 18;19(1):64
Elaiophylin targets EIF4B to suppress the growth of esophageal squamous cell carcinoma via the PI3K/AKT signaling pathway.
Qiu H, Gao L, Shi W, Wang J, Li B, Ke S, Chen J, Gong Y, Wu Y, Zhao W, Chen Y
Cancer letters 2024 Dec 16;611:217401
Cancer letters 2024 Dec 16;611:217401
Inhibition of AhR disrupts intestinal epithelial barrier and induces intestinal injury by activating NF-κB in COPD.
Tao L, Zhang Q, Liu L, Wang K, Wang J, Liu X, Zhao P, Li J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Dec 13;38(24):e70256
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Dec 13;38(24):e70256
Has_circ_0002360 facilitates immune evasion by enhancing heterogeneous nuclear ribonucleoprotein A1 stability, thereby promoting malignant progression in non-small cell lung cancer.
Fan J, Xue L, Lu R, Liu J, Luo J
Experimental cell research 2024 Dec 1;443(2):114312
Experimental cell research 2024 Dec 1;443(2):114312
Nicotinamide protects against diabetic kidney disease through regulation of Sirt1.
Yang Y, Huang J, Xie L, Wang Y, Guo S, Wang M, Shao X, Liu W, Wang Y, Li Q, Wu X, Zhang Z, Zeng F, Gong W
Endocrine 2024 Aug;85(2):638-648
Endocrine 2024 Aug;85(2):638-648
Long non-coding RNA H19 mediates the miR-29b/transforming growth factor-β1/Drosophila mothers against decapentaplegic 3 signalling pathway to promote bladder fibrosis in diabetic rats.
Sun J, Du Q, Zhao L, Huang J, Yu H, Ding H, Mao D, Tai S
International urology and nephrology 2024 Aug;56(8):2779-2791
International urology and nephrology 2024 Aug;56(8):2779-2791
Dexmedetomidine promotes colorectal cancer progression via Piwil2 signaling.
Dong J, Che J, Wu Y, Deng Y, Jiang X, He Z, Zhang J
Cellular oncology (Dordrecht, Netherlands) 2024 Aug;47(4):1459-1474
Cellular oncology (Dordrecht, Netherlands) 2024 Aug;47(4):1459-1474
IFIT1 modulates the proliferation, migration and invasion of pancreatic cancer cells via Wnt/β-catenin signaling.
Li TH, Zhao BB, Qin C, Wang YY, Li ZR, Cao HT, Yang XY, Zhou XT, Wang WB
Cellular oncology (Dordrecht, Netherlands) 2024 Aug;47(4):1253-1265
Cellular oncology (Dordrecht, Netherlands) 2024 Aug;47(4):1253-1265
STIL facilitates the development and malignant progression of triple-negative breast cancer through activation of Fanconi anemia pathway via interacting with KLF16.
Wang M, Pan B, Hu Y, Gao J, Hou L, Yu Z, Li M, Zhao Z
Translational oncology 2024 Aug;46:102010
Translational oncology 2024 Aug;46:102010
N6-methyladenosine modified circPAK2 promotes lymph node metastasis via targeting IGF2BPs/VEGFA signaling in gastric cancer.
Ding P, Wu H, Wu J, Li T, He J, Ju Y, Liu Y, Li F, Deng H, Gu R, Zhang L, Guo H, Tian Y, Yang P, Meng N, Li X, Guo Z, Meng L, Zhao Q
Oncogene 2024 Aug;43(34):2548-2563
Oncogene 2024 Aug;43(34):2548-2563
Autocatalytic, Brain Tumor-Targeting Delivery of Bardoxolone Methyl Self-Assembled Nanoparticles for Glioblastoma Treatment.
Ye Z, Sheu WC, Qu H, Peng B, Liu J, Zhang L, Yuan F, Wei Y, Zhou J, Chen Q, Xiao X, Zhang S
Small science 2024 Aug;4(8):2400081
Small science 2024 Aug;4(8):2400081
Role of transient receptor potential vanilloid 4 channels in an ovalbumin-induced murine food allergic model.
Murayama Y, Tabuchi M, Utsumi D, Naruse K, Tokuyama K, Ikedo A, Morimasa E, Kato S, Matsumoto K
Naunyn-Schmiedeberg's archives of pharmacology 2024 Aug;397(8):6061-6074
Naunyn-Schmiedeberg's archives of pharmacology 2024 Aug;397(8):6061-6074
Biological effect of ETV4 and the underlying mechanism of its regulatory effect on epithelial‑mesenchymal transition in intrahepatic cholangiocarcinoma cells.
Liu L, Feng Y, Xiang X, Xu M, Tang G
Oncology letters 2024 Aug;28(2):346
Oncology letters 2024 Aug;28(2):346
Exosomal miR-130b-3p suppresses metastasis of non-small cell lung cancer cells by targeting DEPDC1 via TGF-β signaling pathway.
Lv M, Li X, Zheng C, Tian W, Yang H, Yin Z, Zhou B
International journal of biological macromolecules 2024 Aug;275(Pt 1):133594
International journal of biological macromolecules 2024 Aug;275(Pt 1):133594
P4HA3 promotes head and neck squamous cell carcinoma progression via the WNT/β-catenin signaling pathway.
Wang Q, Meng D, Shen S, Cao Y, Zhang P, Liu Y, Du L, Li H, Shao C, Dong Q
Pathology, research and practice 2024 Aug;260:155481
Pathology, research and practice 2024 Aug;260:155481
INPP4B suppresses HER2-induced mesenchymal transition in HER2+ breast cancer and enhances sensitivity to Lapatinib.
Qu N, Wang G, Su Y, Chen B, Zhou D, Wu Y, Yuan L, Yin M, Liu M, Peng Y, Zhou W
Biochemical pharmacology 2024 Aug;226:116347
Biochemical pharmacology 2024 Aug;226:116347
Infection of human organoids supports an intestinal niche for Chlamydia trachomatis.
Hovhannisyan P, Stelzner K, Keicher M, Paprotka K, Neyazi M, Pauzuolis M, Ali WM, Rajeeve K, Bartfeld S, Rudel T
PLoS pathogens 2024 Aug;20(8):e1012144
PLoS pathogens 2024 Aug;20(8):e1012144
Changes in PI3K/AKT and NRF2/HO-1 signaling expression and intestinal microbiota in bleomycin-induced pulmonary fibrosis.
Li C, Cao Y, Peng Y, Ma T, Wu F, Hua Y, Wang X, Bai T, Wei Y, Ji P
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Aug;190:114796
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Aug;190:114796
Anti-ulcerative colitis effect of rotating magnetic field on DSS-induced mice by modulating colonic inflammatory deterioration.
Yang H, Zhou C, Nie S, Xu S, Li M, Yu Q, Wei Y, Wang X
Molecular immunology 2024 Aug;172:23-37
Molecular immunology 2024 Aug;172:23-37
Integrated multi-omics profiling landscape of organising pneumonia.
Tang Y, Chu C, Bu S, Sun Q, Liu A, Xie J, Qiao S, Huang L, Wang H
Clinical and translational medicine 2024 Aug;14(8):e1782
Clinical and translational medicine 2024 Aug;14(8):e1782
Aloperine Suppresses Cancer Progression by Interacting with VPS4A to Inhibit Autophagosome-lysosome Fusion in NSCLC.
Guo W, Zhou H, Wang J, Lu J, Dong Y, Kang Z, Qiu X, Ouyang X, Chen Q, Li J, Cheng X, Du K, Li M, Lin Z, Jin M, Zhang L, Sarapultsev A, Shi K, Li F, Zhang G, Wu K, Rong Y, Heissmeyer V, Liu Y, Li Y, Huang K, Luo S, Hu D
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(31):e2308307
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(31):e2308307
STC2 suppresses triple-negative breast cancer migration and invasion by inhibition on EMT and promotion on cell apoptosis.
Lei R, Yao C, Huang R, Wu W, Ou L, Yang C
Discover oncology 2024 Aug 9;15(1):339
Discover oncology 2024 Aug 9;15(1):339
TCF12-regulated GRB7 facilitates the HER2+ breast cancer progression by activating Notch1 signaling pathway.
Wang G, Wu Y, Su Y, Qu N, Chen B, Zhou D, Yuan L, Yin M, Liu M, Zhou W
Journal of translational medicine 2024 Aug 7;22(1):745
Journal of translational medicine 2024 Aug 7;22(1):745
Hypoxia exacerbates the malignant transformation of gastric epithelial cells induced by long-term H. pylori infection.
He Y, Zhang X, Zhang X, Fu B, Xing J, Fu R, Lv J, Guo M, Huo X, Liu X, Lu J, Cao L, Du X, Ge Z, Chen Z, Lu X, Li C
Microbiology spectrum 2024 Aug 6;12(8):e0031124
Microbiology spectrum 2024 Aug 6;12(8):e0031124
OTU deubiquitinase, ubiquitin aldehyde binding 2 (OTUB2) modulates the stemness feature, chemoresistance, and epithelial-mesenchymal transition of colon cancer via regulating GINS complex subunit 1 (GINS1) expression.
Zhu W, Wu C, Liu Z, Zhao S, Huang J
Cell communication and signaling : CCS 2024 Aug 29;22(1):420
Cell communication and signaling : CCS 2024 Aug 29;22(1):420
Capsaicin combined with cisplatin inhibits TGF-β1-induced EMT and TSCC cells migration via the Claudin-1/PI3K/AKT/mTOR signaling pathway.
Li Z, Zhao Q, Liu X, Zhou X, Wang Y, Zhao M, Wu F, Zhao G, Guo X
Cancer cell international 2024 Aug 28;24(1):300
Cancer cell international 2024 Aug 28;24(1):300
A CLIC1 network coordinates matrix stiffness and the Warburg effect to promote tumor growth in pancreatic cancer.
Zheng JH, Zhu YH, Yang J, Ji PX, Zhao RK, Duan ZH, Yao HF, Jia QY, Yin YF, Hu LP, Li Q, Jiang SH, Huo YM, Liu W, Sun YW, Liu DJ
Cell reports 2024 Aug 27;43(8):114633
Cell reports 2024 Aug 27;43(8):114633
Acetylation of PGK1 at lysine 323 promotes glycolysis, cell proliferation, and metastasis in luminal A breast cancer cells.
Gao X, Pan T, Gao Y, Zhu W, Liu L, Duan W, Han C, Feng B, Yan W, Song Q, Liu Y, Yue L
BMC cancer 2024 Aug 27;24(1):1054
BMC cancer 2024 Aug 27;24(1):1054
TRIP13 regulates progression of gastric cancer through stabilising the expression of DDX21.
Zhang G, Yang R, Wang B, Yan Q, Zhao P, Zhang J, Su W, Yang L, Cui H
Cell death & disease 2024 Aug 26;15(8):622
Cell death & disease 2024 Aug 26;15(8):622
RARB associated with MSI, affects progression and prognosis of gastric cancer.
Cai X, Lin W, Wu F, Song G, Qian Z, Wang Y
BMC gastroenterology 2024 Aug 23;24(1):285
BMC gastroenterology 2024 Aug 23;24(1):285
Role of gut microbiota in Crohn's disease pathogenesis: Insights from fecal microbiota transplantation in mouse model.
Wu Q, Yuan LW, Yang LC, Zhang YW, Yao HC, Peng LX, Yao BJ, Jiang ZX
World journal of gastroenterology 2024 Aug 21;30(31):3689-3704
World journal of gastroenterology 2024 Aug 21;30(31):3689-3704
Repurposed AT9283 triggers anti-tumoral effects by targeting MKK3 oncogenic functions in Colorectal Cancer.
Piastra V, Ganci F, Sacconi A, Pranteda A, Allegretti M, Bernardini R, Serra M, Lupo B, Dell'Aquila E, Ferretti G, Pescarmona E, Bartolazzi A, Blandino G, Trusolino L, Bossi G
Journal of experimental & clinical cancer research : CR 2024 Aug 20;43(1):234
Journal of experimental & clinical cancer research : CR 2024 Aug 20;43(1):234
FAM122A functions as a tumor suppressor in oral squamous cell carcinoma.
Zhu H, Huang Y, Chen J
Experimental cell research 2024 Aug 15;441(2):114165
Experimental cell research 2024 Aug 15;441(2):114165
Matrine Suppresses Arsenic-Induced Malignant Transformation of SV-HUC-1 Cells via NOX2.
Wang L, Qiu N, Tong S, Yu Y, Xi S, Wang F
International journal of molecular sciences 2024 Aug 15;25(16)
International journal of molecular sciences 2024 Aug 15;25(16)
RGS10 deficiency facilitates distant metastasis by inducing epithelial-mesenchymal transition in breast cancer.
Liu Y, Jiang Y, Qiu P, Ma T, Bai Y, Bu J, Hu Y, Jin M, Zhu T, Gu X
eLife 2024 Aug 15;13
eLife 2024 Aug 15;13
Does rAj-Tspin, a novel peptide from A. japonicus, exert antihepatocellular carcinoma effects via the ITGB1/ZYX/FAK/AKT signaling pathway?
Che Y, Lu X, Wang X, Liu Z, Guan L, Li X, Du Z, Ren H, Wang J, Zhou Z, Lv L
Cancer cell international 2024 Aug 14;24(1):290
Cancer cell international 2024 Aug 14;24(1):290
Pt(iv) derivatives of cisplatin and oxaliplatin bearing an EMT-related TMEM16A/COX-2-selective dual inhibitor against colorectal cancer cells HCT116.
Ma ZY, Ding XJ, Zhu ZZ, Chen Q, Wang DB, Qiao X, Xu JY
RSC medicinal chemistry 2024 Aug 1;15(9):3239-47
RSC medicinal chemistry 2024 Aug 1;15(9):3239-47
RAE1 promotes gastric carcinogenesis and epithelial-mesenchymal transition.
Dong W, Li X, Cheng L, Yang J, Zhao Z, Qiang X, Li P, Wu J, Guo L
Archives of biochemistry and biophysics 2024 Apr;754:109896
Archives of biochemistry and biophysics 2024 Apr;754:109896
Kinesin Family Member-18A (KIF18A) Promotes Cell Proliferation and Metastasis in Hepatocellular Carcinoma.
Ren J, Yao X, Yang M, Cheng S, Wu D, Xu K, Li R, Zhang H, Zhang D
Digestive diseases and sciences 2024 Apr;69(4):1274-1286
Digestive diseases and sciences 2024 Apr;69(4):1274-1286
The FOXO1/G6PC axis promotes gastric cancer progression and mediates 5-fluorouracil resistance by targeting the PI3K/AKT/mTOR signaling pathway.
Han A, Liu T, Du P, Wang M, Liu J, Chen L
Molecular carcinogenesis 2024 Apr;63(4):688-700
Molecular carcinogenesis 2024 Apr;63(4):688-700
E3 ubiquitin ligase NEDD4L inhibits epithelial-mesenchymal transition by suppressing the β-catenin/HIF-1α positive feedback loop in chronic rhinosinusitis with nasal polyps.
Chen SY, Liu PQ, Qin DX, Lv H, Zhou HQ, Xu Y
Acta pharmacologica Sinica 2024 Apr;45(4):831-843
Acta pharmacologica Sinica 2024 Apr;45(4):831-843
Bone morphogenetic protein 6 (BMP6) antagonises experimental proliferative vitreoretinopathy established by TGF-β2 stimulation in retinal pigment epithelial cells through modulation of the p38 and JNK MAPK pathways.
Liu X, Liu M, Chen L
Cell and tissue research 2024 Apr;396(1):103-117
Cell and tissue research 2024 Apr;396(1):103-117
Propofol-induced LINC01133 inhibits the progression of colorectal cancer via miR-186-5p/NR3C2 axis.
Yao Y, Zhang F, Liu F, Xia D
Environmental toxicology 2024 Apr;39(4):2265-2284
Environmental toxicology 2024 Apr;39(4):2265-2284
Supramolecular Hydrogel with Ultra-Rapid Cell-Mediated Network Adaptation for Enhancing Cellular Metabolic Energetics and Tissue Regeneration.
Li Z, Yang B, Yang Z, Xie X, Guo Z, Zhao J, Wang R, Fu H, Zhao P, Zhao X, Chen G, Li G, Wei F, Bian L
Advanced materials (Deerfield Beach, Fla.) 2024 Apr;36(15):e2307176
Advanced materials (Deerfield Beach, Fla.) 2024 Apr;36(15):e2307176
FERMT2 upregulation in CAFs enhances EMT of OSCC and M2 macrophage polarization.
Ma X, Zhao D, Liu S, Zuo J, Wang W, Wang F, Li Y, Ding Z, Wang J, Wang X
Oral diseases 2024 Apr;30(3):991-1003
Oral diseases 2024 Apr;30(3):991-1003
CHL1 inhibits cell proliferation, migration and invasion by regulating the NF‑κB signaling pathway in colorectal cancer.
Bao M, Li S, Zhu Y, Dong X, Wang R, Jing F
Experimental and therapeutic medicine 2024 Apr;27(4):165
Experimental and therapeutic medicine 2024 Apr;27(4):165
Chloroxine inhibits pancreatic cancer progression through targeted antagonization of the PI3K/AKT/mTOR signaling pathway.
Lin M, Xiao Y, Dai Y, Mao Y, Xu L, Zhang Q, Chen Z
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2024 Apr;26(4):951-965
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2024 Apr;26(4):951-965
PlexinA1 promotes gastric cancer migration through preventing MICAL1 protein ubiquitin/proteasome-mediated degradation in a Rac1-dependent manner.
Ye F, Xia T, Zhao M, Zhao W, Min P, Wang Y, Wang Q, Zhang Y, Du J
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167124
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167124
PI3Kδ Mediates Fibrosis by Patient-Derived Vitreous.
Liu D, Yan B, Yin Y, Chen F, Guo C, Li Q, Liu J, Pu L, Wu W, Luo J
Laboratory investigation; a journal of technical methods and pathology 2024 Apr;104(4):102026
Laboratory investigation; a journal of technical methods and pathology 2024 Apr;104(4):102026
Fusobacterium periodonticum BCT protein targeting glucose metabolism to promote the epithelial-mesenchymal transition of esophageal cancer cells by lactic acid.
Guo X, Wan P, Shen W, Sun M, Peng Z, Liao Y, Huang Y, Liu R
Journal of translational medicine 2024 Apr 30;22(1):401
Journal of translational medicine 2024 Apr 30;22(1):401
The Natural Product Secoemestrin C Inhibits Colorectal Cancer Stem Cells via p38-S100A8 Feed-Forward Regulatory Loop.
Zhou H, Chen M, Zhao C, Shao R, Xu Y, Zhao W
Cells 2024 Apr 3;13(7)
Cells 2024 Apr 3;13(7)
HIST3H2A promotes the progression of prostate cancer through inhibiting cell necroptosis.
Yang L, Ruan Y, Xu H
BMC cancer 2024 Apr 29;24(1):544
BMC cancer 2024 Apr 29;24(1):544
RETRACTED: High PGC-1α Expression as a Poor Prognostic Indicator in Intracranial Glioma.
Cheng YW, Lee JH, Chang CH, Tseng TT, Chai CY, Lieu AS, Kwan AL
Biomedicines 2024 Apr 29;12(5)
Biomedicines 2024 Apr 29;12(5)
Tabersonine Enhances Olaparib Sensitivity through FHL1-Mediated Epithelial-Mesenchymal Transition in an Ovarian Tumor.
Chen X, Yan Y, Liu Y, Yi Q, Xu Z
Journal of natural products 2024 Apr 26;87(4):837-848
Journal of natural products 2024 Apr 26;87(4):837-848
AKR1B10 accelerates glycolysis through binding HK2 to promote the malignant progression of oral squamous cell carcinoma.
Cai Y, Li H, Xie D, Zhu Y
Discover oncology 2024 Apr 26;15(1):132
Discover oncology 2024 Apr 26;15(1):132
DCDC2 inhibits hepatic stellate cell activation and ameliorates CCl(4)-induced liver fibrosis by suppressing Wnt/β-catenin signaling.
Liu QQ, Chen J, Ma T, Huang W, Lu CH
Scientific reports 2024 Apr 24;14(1):9425
Scientific reports 2024 Apr 24;14(1):9425
hnRNPU is required for spermatogonial stem cell pool establishment in mice.
Wen Y, Zhou S, Gui Y, Li Z, Yin L, Xu W, Feng S, Ma X, Gan S, Xiong M, Dong J, Cheng K, Wang X, Yuan S
Cell reports 2024 Apr 23;43(4):114113
Cell reports 2024 Apr 23;43(4):114113
Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome.
Wu S, Dai X, Xia Y, Zhao Q, Zhao H, Shi Z, Yin X, Liu X, Zhang A, Yao Z, Zhang H, Li Q, Thorne RF, Zhang S, Sheng W, Hu W, Gu H
Cell reports 2024 Apr 23;43(4):114111
Cell reports 2024 Apr 23;43(4):114111
N6-methyladenosine-modified circSLCO1B3 promotes intrahepatic cholangiocarcinoma progression via regulating HOXC8 and PD-L1.
Li J, Xu X, Xu K, Zhou X, Wu K, Yao Y, Liu Z, Chen C, Wang L, Sun Z, Jiao D, Han X
Journal of experimental & clinical cancer research : CR 2024 Apr 20;43(1):119
Journal of experimental & clinical cancer research : CR 2024 Apr 20;43(1):119
The NF-κB/NUAK2 signaling axis regulates pancreatic cancer progression by targeting SMAD2/3.
Wang R, Su D, Liu Y, Huang H, Qiu J, Cao Z, Yang G, Chen H, Luo W, Tao J, Weng G, Zhang T
iScience 2024 Apr 19;27(4):109406
iScience 2024 Apr 19;27(4):109406
PRMT6-mediated transcriptional activation of ythdf2 promotes glioblastoma migration, invasion, and emt via the wnt-β-catenin pathway.
Yu P, Xu T, Ma W, Fang X, Bao Y, Xu C, Huang J, Sun Y, Li G
Journal of experimental & clinical cancer research : CR 2024 Apr 18;43(1):116
Journal of experimental & clinical cancer research : CR 2024 Apr 18;43(1):116
MFG-E8 induces epithelial-mesenchymal transition and anoikis resistance to promote the metastasis of pancreatic cancer cells.
Liu W, Ren Y, Wang T, Wang M, Xu Y, Zhang J, Bi J, Wu Z, Lv Y, Wu R
European journal of pharmacology 2024 Apr 15;969:176462
European journal of pharmacology 2024 Apr 15;969:176462
hsa_circ_0007919 promotes pancreatic cancer metastasis by modulating Sp1-mediated THBS1 transcription.
Ma X, Xu L, Gong S, Wu N, Guo J, Feng X, Zhao M, Qiu S, Sun M, Zhang C, Zhang X, Ren Z, Zhang P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23591
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23591
JMJD3 activation contributes to renal protection and regeneration following acute kidney injury in mice.
Yu C, Tang J, Yu J, Wang Y, Liu N, Dong Z, Zhuang S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23583
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23583
Butyrate attenuates the stemness of lung cancer cells through lysosome Fe(2+)- and SLC7A11-mediated ferroptosis.
Bi R, Jiang L, Hu R, Wen B, Jiang Z, Liu H, Mei J
Heliyon 2024 Apr 15;10(7):e28093
Heliyon 2024 Apr 15;10(7):e28093
Hawthorn Proanthocyanidin Extract Inhibits Colorectal Carcinoma Metastasis by Targeting the Epithelial-Mesenchymal Transition Process and Wnt/β-Catenin Signaling Pathway.
Wang Z, Sun Y, Wu M, Zhou L, Zheng Y, Ren T, Li M, Zhao W
Foods (Basel, Switzerland) 2024 Apr 12;13(8)
Foods (Basel, Switzerland) 2024 Apr 12;13(8)
Inhibition of PD-L1 expression in non-small cell lung cancer may reduce vasculogenic mimicry formation by inhibiting the epithelial mesenchymal transformation process.
Shi Y, Li W, Jia Q, Wu J, Wu S, Wu S
Experimental cell research 2024 Apr 1;437(1):113996
Experimental cell research 2024 Apr 1;437(1):113996
Adhesive hydrogel releases protocatechualdehyde-Fe(3+) complex to promote three healing stages for accelerated therapy of oral ulcers.
Wang Y, Pan Z, Cui J, Zhang X, Li D, Sun H, Yang B, Li Y
Acta biomaterialia 2024 Apr 1;178:68-82
Acta biomaterialia 2024 Apr 1;178:68-82
CircGPC3 promotes hepatocellular carcinoma progression and metastasis by sponging miR-578 and regulating RAB7A/PSME3 expression.
Ju L, Luo Y, Cui X, Zhang H, Chen L, Yao M
Scientific reports 2024 Apr 1;14(1):7632
Scientific reports 2024 Apr 1;14(1):7632
Echinacoside alleviates airway remodeling and inflammation in an ovalbumin-induced neonatal mouse model of asthma by modulating the SIRT1-NF-κB pathway.
Pan Y, Liu Y
Allergologia et immunopathologia 2023;51(4):71-77
Allergologia et immunopathologia 2023;51(4):71-77
Tetrandrine Inhibits Cancer Stem Cell Characteristics and Epithelial to Mesenchymal Transition in Triple-Negative Breast Cancer via SOD1/ROS Signaling Pathway.
Liu T, Li K, Zhang Z, Peng J, Yang J, Law BYK, Liu X, Li W
The American journal of Chinese medicine 2023;51(2):425-444
The American journal of Chinese medicine 2023;51(2):425-444
Chlorogenic Acid Inhibited Epithelial-Mesenchymal Transition to Treat Pulmonary Fibrosis through Modulating Autophagy.
Mao X, Xie X, Ma J, Wei Y, Huang Z, Wang T, Zhu J, Wang Y, Zhao H, Hua J
Biological & pharmaceutical bulletin 2023;46(7):929-938
Biological & pharmaceutical bulletin 2023;46(7):929-938
MKRN1/2 serve as tumor suppressors in renal clear cell carcinoma by regulating the expression of p53.
Yang Y, Luo Y, Huang S, Tao Y, Li C, Wang C
Cancer biomarkers : section A of Disease markers 2023;36(4):267-278
Cancer biomarkers : section A of Disease markers 2023;36(4):267-278
Oxidative stress-induced temporal activation of ERK1/2 phosphorylates coreceptor of Wnt/β-catenin for myofibroblast formation in human lens epithelial cells.
Guo Z, Ma X, Chen X, Zhang RX, Yan H
Molecular vision 2023;29:206-216
Molecular vision 2023;29:206-216
Up-regulated SPP1 increases the risk from IPF to lung cancer via activating the pro-tumor macrophages.
Chen T, Guo J, Ai L, Wang Y, Wang Y, Chen B, Liu M, Zhuang S, Liu K, Zhao Z, Liang H, Gu Y
Computational and structural biotechnology journal 2023;21:5751-5764
Computational and structural biotechnology journal 2023;21:5751-5764
The Role of Purine Metabolism-Related Genes PPAT and IMPDH1 in the Carcinogenesis of Intrahepatic Cholangiocarcinoma Based on Metabonomic and Bioinformatic Analyses.
Liu CJ, Ma ZZ, Gong WZ, Mao XH, Wen HQ, Wang XH
Journal of oncology 2023;2023:5141836
Journal of oncology 2023;2023:5141836
The Interaction of Apelin and FGFR1 Ameliorated the Kidney Fibrosis through Suppression of TGFβ-Induced Endothelial-to-Mesenchymal Transition.
Gao R, Wu Y, Yang Q, Chen L, Chen J, Wang B, Liu Z, Jin J, Li J, Wu G
Oxidative medicine and cellular longevity 2023;2023:5012474
Oxidative medicine and cellular longevity 2023;2023:5012474
LncRNA SNHG5 Suppresses Cell Migration and Invasion of Human Lung Adenocarcinoma via Regulation of Epithelial-Mesenchymal Transition.
Li Z, Wu Y, Zhang C, Dai S, Wei S, Zhao R, Gao F, Zhao L, Shan B
Journal of oncology 2023;2023:3335959
Journal of oncology 2023;2023:3335959
lncRNA CRNDE Affects Th17/IL-17A and Inhibits Epithelial-Mesenchymal Transition in Lung Epithelial Cells Reducing Asthma Signs.
Yuan Y, He Y, Wasti B, Duan W, Jia J, Chen Z, Xiang X, Zeng Q
Oxidative medicine and cellular longevity 2023;2023:2092184
Oxidative medicine and cellular longevity 2023;2023:2092184
Lnc NR2F1-AS1 Promotes Breast Cancer Metastasis by Targeting the MiR-25-3p/ZEB2 Axis.
Zhai D, Zhou Y, Kuang X, Shao F, Zhen T, Lin Y, Wang Q, Shao N
International journal of medical sciences 2023;20(9):1152-1162
International journal of medical sciences 2023;20(9):1152-1162
Low Expression of GIGYF1 Inhibits Metastasis, Proliferation, and Promotes Apoptosis and Autophagy of Gastric Cancer Cells.
Zhu L, Yao Z, Luo Q, Liu Y, Zhao W, Shao C, Shao S, Cui F
International journal of medical sciences 2023;20(8):1038-1045
International journal of medical sciences 2023;20(8):1038-1045
Renalase Prevents Renal Fibrosis by Inhibiting Endoplasmic Reticulum Stress and Down-Regulating GSK-3β/Snail Signaling.
Wu Y, Bai Y, Feng Y, Zhang Q, Diao Z, Liu W
International journal of medical sciences 2023;20(5):669-681
International journal of medical sciences 2023;20(5):669-681
PYGL-mediated glucose metabolism reprogramming promotes EMT phenotype and metastasis of pancreatic cancer.
Ji Q, Li H, Cai Z, Yuan X, Pu X, Huang Y, Fu S, Chu L, Jiang C, Xue J, Zhang X, Li R
International journal of biological sciences 2023;19(6):1894-1909
International journal of biological sciences 2023;19(6):1894-1909
Timosaponin AIII promotes non-small-cell lung cancer ferroptosis through targeting and facilitating HSP90 mediated GPX4 ubiquitination and degradation.
Zhou C, Yu T, Zhu R, Lu J, Ouyang X, Zhang Z, Chen Q, Li J, Cui J, Jiang F, Jin KY, Sarapultsev A, Li F, Zhang G, Luo S, Hu D
International journal of biological sciences 2023;19(5):1471-1489
International journal of biological sciences 2023;19(5):1471-1489
BGN/FAP/STAT3 positive feedback loop mediated mutual interaction between tumor cells and mesothelial cells contributes to peritoneal metastasis of gastric cancer.
Wu H, Xiang Z, Huang G, He Q, Song J, Dou R, Yang C, Wang S, Xiong B
International journal of biological sciences 2023;19(2):465-483
International journal of biological sciences 2023;19(2):465-483
System analysis identifies UBE2C as a novel oncogene target for adrenocortical carcinoma.
Huang R, Guo L, Chen C, Xiang Y, Li G, Zheng J, Wu Y, Yuan X, Zhou J, Gao W, Xiang S
PloS one 2023;18(8):e0289418
PloS one 2023;18(8):e0289418
Caffeic acid phenethyl ester suppresses metastasis of breast cancer cells by inactivating FGFR1 via MD2.
Fang Q, Xin W, Chen L, Fu Y, Qi Y, Ding H, Fang L
PloS one 2023;18(7):e0289031
PloS one 2023;18(7):e0289031
Exosome-delivered circRPS5 inhibits the progression of melanoma via regulating the miR-151a/NPTX1 axis.
Zhu H, Zhang P, Shi J, Kou D, Bai X
PloS one 2023;18(6):e0287347
PloS one 2023;18(6):e0287347
Differential effects of WRAP53 transcript variants on non-small cell lung cancer cell behaviors.
Zhu Y, Sun W, Jiang X, Bai R, Luo Y, Gao Y, Li S, Huang Z, Gong Y, Xie C
PloS one 2023;18(1):e0281132
PloS one 2023;18(1):e0281132
Downregulation of KIAA1199 alleviated the activation, proliferation, and migration of hepatic stellate cells by the inhibition of epithelial-mesenchymal transition.
Liu J, Xia S, Han P, Zhang M, Wu J, Liao J
Open medicine (Warsaw, Poland) 2023;18(1):20230689
Open medicine (Warsaw, Poland) 2023;18(1):20230689
Downregulation of RBM17 enhances cisplatin sensitivity and inhibits cell invasion in human hypopharyngeal cancer cells.
Wang X, Chen D, Han G, Wang X, Liu X, Xu B, Liu W, Li H, Zhang M, Ma S, Han Y
Open medicine (Warsaw, Poland) 2023;18(1):20230669
Open medicine (Warsaw, Poland) 2023;18(1):20230669
HDAC5-mediated PRAME regulates the proliferation, migration, invasion, and EMT of laryngeal squamous cell carcinoma via the PI3K/AKT/mTOR signaling pathway.
Yu L, Cao H, Yang JW, Meng WX, Yang C, Wang JT, Yu MM, Wang BS
Open medicine (Warsaw, Poland) 2023;18(1):20230665
Open medicine (Warsaw, Poland) 2023;18(1):20230665
HK2 contributes to the proliferation, migration, and invasion of diffuse large B-cell lymphoma cells by enhancing the ERK1/2 signaling pathway.
Zhao H, Xiang G, Shao T, Wang M, Dai W
Open life sciences 2023;18(1):20220726
Open life sciences 2023;18(1):20220726
Exosome-Delivered circSTAU2 Inhibits the Progression of Gastric Cancer by Targeting the miR-589/CAPZA1 Axis.
Zhang C, Wei G, Zhu X, Chen X, Ma X, Hu P, Liu W, Yang W, Ruan T, Zhang W, Wu C, Tao K
International journal of nanomedicine 2023;18:127-142
International journal of nanomedicine 2023;18:127-142
Jiawei Danxuan Koukang Alleviates Arecoline Induced Oral Mucosal Lesions: Network Pharmacology and the Combined Ultra-High Performance Liquid Chromatography (UPLC) and Mass Spectrometry (MS).
Zhou L, Tan J, Dai Y, Zhu K, Xiao Y, Wu D, Wang Z, Tan Y, Qin Y
Drug design, development and therapy 2023;17:3085-3101
Drug design, development and therapy 2023;17:3085-3101
Integrating Network Pharmacology and Experimental Validation to Explore the Pharmacological Mechanism of Astragaloside IV in Treating Bleomycin-Induced Pulmonary Fibrosis.
Yuan S, Zuo B, Zhou SC, Wang M, Tan KY, Chen ZW, Cao WF
Drug design, development and therapy 2023;17:1289-1302
Drug design, development and therapy 2023;17:1289-1302
Fucosyltransferase 5 Promotes the Proliferative and Migratory Properties of Intrahepatic Cholangiocarcinoma Cells via Regulating Protein Glycosylation Profiles.
Guo J, Cheng Q, Li Y, Tian L, Ma D, Li Z, Gao J, Zhu J
Clinical Medicine Insights. Oncology 2023;17:11795549231181189
Clinical Medicine Insights. Oncology 2023;17:11795549231181189
Escherichia coli Promotes Endothelial to Mesenchymal Transformation of Liver Sinusoidal Endothelial Cells and Exacerbates Nonalcoholic Fatty Liver Disease Via Its Flagellin.
Shen B, Gu T, Shen Z, Zhou C, Guo Y, Wang J, Li B, Xu X, Li F, Zhang Q, Cai X, Dong H, Lu L
Cellular and molecular gastroenterology and hepatology 2023;16(6):857-879
Cellular and molecular gastroenterology and hepatology 2023;16(6):857-879
ZEB1 Transcriptionally Activates PHGDH to Facilitate Carcinogenesis and Progression of HCC.
Wang H, Lin F, Xu Z, Yu S, Li G, Liao S, Zhao W, Zhang F, Wang J, Wang S, Ouyang C, Zhang C, Xia H, Wu Y, Jiang B, Li Q
Cellular and molecular gastroenterology and hepatology 2023;16(4):541-556
Cellular and molecular gastroenterology and hepatology 2023;16(4):541-556
B7 Induces Apoptosis in Colorectal Cancer Cells by Regulating the Expression of Caspase-3 and Inhibits Autophagy.
Zhang X, Li F, Li R, Zhao N, Liu D, Xu Y, Wang L, Wang D, Zhao R
OncoTargets and therapy 2023;16:867-883
OncoTargets and therapy 2023;16:867-883
Esomeprazole Alleviates Cisplatin Resistance by Inhibiting the AKT/mTOR Pathway in Ovarian Cancer Cells.
Duan J, Zhang Z, Du J, Zhang J, Li M, Li C
OncoTargets and therapy 2023;16:425-440
OncoTargets and therapy 2023;16:425-440
Irisin Ameliorates Renal Tubulointerstitial Fibrosis by Regulating the Smad4/β-Catenin Pathway in Diabetic Mice.
Yang Z, Wei J, Wang Y, Du Y, Song S, Li J, Su Z, Shi Y, Wu H
Diabetes, metabolic syndrome and obesity : targets and therapy 2023;16:1577-1593
Diabetes, metabolic syndrome and obesity : targets and therapy 2023;16:1577-1593
The cancer/testis antigen HORMAD1 promotes gastric cancer progression by activating the NF-κB signaling pathway and inducing epithelial-mesenchymal transition.
Bian G, Li W, Huang D, Zhang Q, Ding X, Zang X, Ye Y, Cao J, Li P
American journal of translational research 2023;15(9):5808-5825
American journal of translational research 2023;15(9):5808-5825
ALKBH5-PYCR2 Positive Feedback Loop Promotes Proneural-Mesenchymal Transition Via Proline Synthesis In GBM.
Li L, Yang M, Pu X, Tang Y, Fei F, Li Z, Hou H, Chen Q, Wang Q, Wu Y, Zhang Y, Ren C, Gong A
Journal of Cancer 2023;14(9):1579-1591
Journal of Cancer 2023;14(9):1579-1591
Suppression of Wnt/β-catenin Signaling in PDAC via METTL16-mediated N6-methyladenosine Modification of DVL2.
Yu L, Lu J, Xie N, Fang L, Chen S, Wu Y, Wang X, Li B
Journal of Cancer 2023;14(16):2964-2977
Journal of Cancer 2023;14(16):2964-2977
LncRNA HOTAIR Enhances Epithelial-to-mesenchymal Transition to Promote the Migration and Invasion of Liver Cancer by Regulating NUAK1 via Epigenetic Inhibition miR-145-5p Expression.
Chu DX, Jin Y, Wang BR, Jiao Y, Zhang CK, Guo ZH, Hu SZ, Li N
Journal of Cancer 2023;14(12):2329-2343
Journal of Cancer 2023;14(12):2329-2343
High SGO2 predicted poor prognosis and high therapeutic value of lung adenocarcinoma and promoted cell proliferation, migration, invasion, and epithelial-to-mesenchymal transformation.
Wu Z, Zhuo T, Li Z, Zhu Y, Wu J, Liang G, Dai L, Wang Y, Tan X, Chen M
Journal of Cancer 2023;14(12):2301-2314
Journal of Cancer 2023;14(12):2301-2314
Myricetin suppresses TGF-β-induced epithelial-to-mesenchymal transition in ovarian cancer.
Yang HW, Lan Y, Li A, Wu H, Song ZW, Wan AL, Wang Y, Li SB, Ji S, Wang ZC, Wu XY, Lan T
Frontiers in pharmacology 2023;14:1288883
Frontiers in pharmacology 2023;14:1288883
Ultrasound-assisted intravesical botulinum toxin A delivery attenuates acetic acid-induced bladder hyperactivity in rats.
Liu Q, Gao Y, Cong H, Liao L
Frontiers in pharmacology 2023;14:1214145
Frontiers in pharmacology 2023;14:1214145
APOC1 exacerbates renal fibrosis through the activation of the NF-κB signaling pathway in IgAN.
Yu K, Ding L, An X, Yang Y, Zhang X, Li L, Wang C, Bai F, Yang X
Frontiers in pharmacology 2023;14:1181435
Frontiers in pharmacology 2023;14:1181435
The role of the SGK3/TOPK signaling pathway in the transition from acute kidney injury to chronic kidney disease.
Shu H, Wang Y, Zhang H, Dong Q, Sun L, Tu Y, Liao Q, Feng L, Yao L
Frontiers in pharmacology 2023;14:1169054
Frontiers in pharmacology 2023;14:1169054
A novel prognostic signatures based on metastasis- and immune-related gene pairs for colorectal cancer.
Pan B, Yue Y, Ding W, Sun L, Xu M, Wang S
Frontiers in immunology 2023;14:1161382
Frontiers in immunology 2023;14:1161382
Exploration of epithelial-mesenchymal transition-related lncRNA signature and drug sensitivity in breast cancer.
Li C, Zheng L, Xu G, Yuan Q, Di Z, Yang Y, Dong X, Hou J, Wu G
Frontiers in endocrinology 2023;14:1154741
Frontiers in endocrinology 2023;14:1154741
Establishment of a porcine bronchial epithelial cell line and its application to study innate immunity in the respiratory epithelium.
Fukuyama K, Zhuang T, Toyoshi E, Raya Tonetti F, Saha S, Zhou B, Ikeda-Ohtsubo W, Nishiyama K, Aso H, Villena J, Kitazawa H
Frontiers in immunology 2023;14:1117102
Frontiers in immunology 2023;14:1117102
Investigating the role of FADS family members in breast cancer based on bioinformatic analysis and experimental validation.
Zhao T, Gao P, Li Y, Tian H, Ma D, Sun N, Chen C, Zhang Y, Qi X
Frontiers in immunology 2023;14:1074242
Frontiers in immunology 2023;14:1074242
Spider venom-derived peptide JZTX-14 prevents migration and invasion of breast cancer cells via inhibition of sodium channels.
Wu W, Yin Y, Feng P, Chen G, Pan L, Gu P, Zhou S, Lin F, Ji S, Zheng C, Deng M
Frontiers in pharmacology 2023;14:1067665
Frontiers in pharmacology 2023;14:1067665
A novel risk model of three SUMOylation genes based on RNA expression for potential prognosis and treatment sensitivity prediction in kidney cancer.
Li SC, Yan LJ, Wei XL, Jia ZK, Yang JJ, Ning XH
Frontiers in pharmacology 2023;14:1038457
Frontiers in pharmacology 2023;14:1038457
The prognostic value of the GPAT/AGPAT gene family in hepatocellular carcinoma and its role in the tumor immune microenvironment.
Wen P, Wang R, Xing Y, Ouyang W, Yuan Y, Zhang S, Liu Y, Peng Z
Frontiers in immunology 2023;14:1026669
Frontiers in immunology 2023;14:1026669
NPM1 promotes nasopharyngeal carcinoma metastasis and stemness by recruiting Mdm2 to induce the ubiquitination-mediated degradation of p53.
Hu L, Gong P, Zhou N, Wang S, He C, Zhou Y, Li Q, Zhao X, Peng H
American journal of cancer research 2023;13(5):1766-1785
American journal of cancer research 2023;13(5):1766-1785
ZY-444 inhibits the growth and metastasis of prostate cancer by targeting TNFAIP3 through TNF signaling pathway.
Han MT, Pei H, Sun QQ, Wang CL, Li P, Xie YY, Cao LJ, Zhang XX, Sun ZL
American journal of cancer research 2023;13(4):1533-1546
American journal of cancer research 2023;13(4):1533-1546
Circ_0000231 promotes paclitaxel resistance in ovarian cancer by regulating miR-140/RAP1B.
Liu J, Wang H, Xiao S, Zhang S, Qi Y, Wang M
American journal of cancer research 2023;13(3):872-885
American journal of cancer research 2023;13(3):872-885
The deubiquitinating enzyme MINDY2 promotes pancreatic cancer proliferation and metastasis by stabilizing ACTN4 expression and activating the PI3K/AKT/mTOR signaling pathway.
Liu P, Liu S, Zhu C, Li Y, Li Y, Fei X, Hou J, Wang X, Pan Y
Frontiers in oncology 2023;13:1169833
Frontiers in oncology 2023;13:1169833
Aquaporin 9 is involved in CRC metastasis through DVL2-dependent Wnt/β-catenin signaling activation.
Liu Y, Gao Q, Feng X, Chen G, Jiang X, Chen D, Yang Z
Gastroenterology report 2023;11:goad033
Gastroenterology report 2023;11:goad033
FTH1 indicates poor prognosis and promotes metastasis in head and neck squamous cell carcinoma.
Liao Q, Yang J, Lu Z, Jiang Q, Gong Y, Liu L, Peng H, Wang Q, Zhang X, Liu Z
PeerJ 2023;11:e16493
PeerJ 2023;11:e16493
EXOSC10 is a novel hepatocellular carcinoma prognostic biomarker: a comprehensive bioinformatics analysis and experiment verification.
Meng ZY, Fan YC, Zhang CS, Zhang LL, Wu T, Nong MY, Wang T, Chen C, Jiang LH
PeerJ 2023;11:e15860
PeerJ 2023;11:e15860
Effect of stem cell conditional medium-loading adhesive hydrogel on TGF-β1-induced endometrial stromal cell fibrosis.
Zhu Y, Wang T, Bao MJ, Qu XH, Li ZM
Frontiers in bioengineering and biotechnology 2023;11:1168136
Frontiers in bioengineering and biotechnology 2023;11:1168136
Endothelial AHR activity prevents lung barrier disruption in viral infection.
Major J, Crotta S, Finsterbusch K, Chakravarty P, Shah K, Frederico B, D'Antuono R, Green M, Meader L, Suarez-Bonnet A, Priestnall S, Stockinger B, Wack A
Nature 2023 Sep;621(7980):813-820
Nature 2023 Sep;621(7980):813-820
VIRMA facilitates intrahepatic cholangiocarcinoma progression through epigenetic augmentation of TMED2 and PARD3B mRNA stabilization.
Xu H, Lin X, Li Z, He X, Li Y, Qiu L, Lu L, Liu B, Zhan M, He K
Journal of gastroenterology 2023 Sep;58(9):925-944
Journal of gastroenterology 2023 Sep;58(9):925-944
Exosomal miR-21-5p derived from multiple myeloma cells promote renal epithelial-mesenchymal transition through targeting TGF-β/SMAD7 signalling pathway.
Liu L, Liu L, Liu R, Liu J, Cheng Q
Clinical and experimental pharmacology & physiology 2023 Sep;50(9):711-718
Clinical and experimental pharmacology & physiology 2023 Sep;50(9):711-718
CircRNA PDE3B regulates tumorigenicity via the miR-136-5p/MAP3K2 axis of esophageal squamous cell carcinoma.
Yue W, Ye Y, Chen B, Wu D, Wang H, Hui G
Histology and histopathology 2023 Sep;38(9):1029-1041
Histology and histopathology 2023 Sep;38(9):1029-1041
MIR663AHG as a competitive endogenous RNA regulating TGF-β-induced epithelial proliferation and epithelial-mesenchymal transition in benign prostate hyperplasia.
Tong S, Mo M, Hu X, Wu L, Chen M, Zhao C
Journal of biochemical and molecular toxicology 2023 Sep;37(9):e23391
Journal of biochemical and molecular toxicology 2023 Sep;37(9):e23391
Linc-ROR Promotes EMT by Targeting miR-204-5p/SMAD4 in Endometriosis.
Yi M, Wang S, Zhang X, Jiang L, Xia X, Zhang T, Fang X
Reproductive sciences (Thousand Oaks, Calif.) 2023 Sep;30(9):2665-2679
Reproductive sciences (Thousand Oaks, Calif.) 2023 Sep;30(9):2665-2679
Glutaredoxin 2 protects lens epithelial cells from epithelial-mesenchymal transition by suppressing mitochondrial oxidative stress-related upregulation of integrin-linked kinase.
Chen X, Chen Y, Li C, Li J, Zhang S, Liang C, Deng Q, Guo Z, Guo C, Yan H
Experimental eye research 2023 Sep;234:109609
Experimental eye research 2023 Sep;234:109609
Estrogens drive the endoplasmic reticulum-associated degradation and promote proto-oncogene c-Myc expression in prostate cancer cells by androgen receptor/estrogen receptor signaling.
Erzurumlu Y, Dogan HK, Catakli D, Aydogdu E, Muhammed MT
Journal of cell communication and signaling 2023 Sep;17(3):793-811
Journal of cell communication and signaling 2023 Sep;17(3):793-811
Pharmacological inhibition of SMYD2 protects against cisplatin-induced renal fibrosis and inflammation.
Chen M, Zuo S, Chen S, Li X, Zhang T, Yang D, Zou X, Yang Y, Long H, Peng R, Yuan H, Guo B, Liu L
Journal of pharmacological sciences 2023 Sep;153(1):38-45
Journal of pharmacological sciences 2023 Sep;153(1):38-45
UBE3A and MCM6 synergistically regulate the proliferation and migration of lung adenocarcinoma cells.
Luo Y, Yang Y, Yang C, Li C, Hu R, Geng W, Kang X, Lin H
FEBS open bio 2023 Sep;13(9):1756-1771
FEBS open bio 2023 Sep;13(9):1756-1771
Type 2 innate lymphoid cell-derived amphiregulin regulates type II alveolar epithelial cell transdifferentiation in a mouse model of bronchopulmonary dysplasia.
Yao HC, Zhu Y, Lu HY, Ju HM, Xu SQ, Qiao Y, Wei SJ
International immunopharmacology 2023 Sep;122:110672
International immunopharmacology 2023 Sep;122:110672
ACSL4 promotes ferroptosis and M1 macrophage polarization to regulate the tumorigenesis of nasopharyngeal carcinoma.
Chen P, Wang D, Xiao T, Gu W, Yang H, Yang M, Wang H
International immunopharmacology 2023 Sep;122:110629
International immunopharmacology 2023 Sep;122:110629
Maintenance of airway epithelial barrier integrity via the inhibition of AHR/EGFR activation ameliorates chronic obstructive pulmonary disease using effective-component combination.
Wei Y, Liu X, Jiang Y, Guan Q, Tian Y, Li J, Zhao P
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154980
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154980
FTZ polysaccharides ameliorate kidney injury in diabetic mice by regulating gut-kidney axis.
Lan T, Tang T, Li Y, Duan Y, Yuan Q, Liu W, Ren Y, Li N, Liu X, Zhang Y, Li X, Jin G, Wang S, Guo J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154935
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154935
Calycosin inhibits triple-negative breast cancer progression through down-regulation of the novel estrogen receptor-α splice variant ER-α30-mediated PI3K/AKT signaling pathway.
Li Y, Hu S, Chen Y, Zhang X, Gao H, Tian J, Chen J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154924
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154924
Disulfiram suppresses epithelial-mesenchymal transition (EMT), migration and invasion in cervical cancer through the HSP90A/NDRG1 pathway.
Zheng P, Wu Y, Wang Y, Hu F
Cellular signalling 2023 Sep;109:110771
Cellular signalling 2023 Sep;109:110771
GART Functions as a Novel Methyltransferase in the RUVBL1/β-Catenin Signaling Pathway to Promote Tumor Stemness in Colorectal Cancer.
Tang C, Ke M, Yu X, Sun S, Luo X, Liu X, Zhou Y, Wang Z, Cui X, Gu C, Yang Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(25):e2301264
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(25):e2301264
Macrophage migration inhibitory factor exacerbates asthmatic airway remodeling via dynamin-related protein 1-mediated autophagy activation.
Liu J, Chen Y, Chen H, Wang Y, Li D, Zhang Q, Chai L, Qiu Y, Zhang J, Shen N, Wang Q, Wang J, Li M
Respiratory research 2023 Sep 6;24(1):216
Respiratory research 2023 Sep 6;24(1):216
CBX3 promotes clear cell renal carcinoma through PI3K/AKT activation and aberrant immunity.
Chen J, Lin Y, Zheng S, Chen Q, Tang S, Zhong X
Journal of translational medicine 2023 Sep 6;21(1):600
Journal of translational medicine 2023 Sep 6;21(1):600
Pleckstrin-2 promotes tumour immune escape from NK cells by activating the MT1-MMP-MICA signalling axis in gastric cancer.
Mao D, Zhou Z, Chen H, Liu X, Li D, Chen X, He Y, Liu M, Zhang C
Cancer letters 2023 Sep 28;572:216351
Cancer letters 2023 Sep 28;572:216351
Long non-coding RNA MIDEAS-AS1 inhibits growth and metastasis of triple-negative breast cancer via transcriptionally activating NCALD.
Luo D, Liang Y, Wang Y, Ye F, Jin Y, Li Y, Han D, Wang Z, Chen B, Zhao W, Wang L, Chen X, Jiang L, Yang Q
Breast cancer research : BCR 2023 Sep 28;25(1):109
Breast cancer research : BCR 2023 Sep 28;25(1):109
Intercellular adhesion molecule 2 as a novel prospective tumor suppressor induced by ERG promotes ubiquitination-mediated radixin degradation to inhibit gastric cancer tumorigenicity and metastasis.
Tang X, Huang J, Jiang Y, Qiu J, Li T, Li W, Chen Z, Huang Z, Yu X, Yang T, Ji X, Tan R, Lv L, Yang Z, Chen H
Journal of translational medicine 2023 Sep 27;21(1):670
Journal of translational medicine 2023 Sep 27;21(1):670
E-Cadherin Is Expressed in Epithelial Cells of the Choroid Plexus in Human and Mouse Brains.
Takebayashi G, Chiba Y, Wakamatsu K, Murakami R, Miyai Y, Matsumoto K, Uemura N, Yanase K, Shirakami G, Ogino Y, Ueno M
Current issues in molecular biology 2023 Sep 26;45(10):7813-7826
Current issues in molecular biology 2023 Sep 26;45(10):7813-7826
Nuciferine Inhibits Oral Squamous Cell Carcinoma Partially through Suppressing the STAT3 Signaling Pathway.
Xie JR, Chen XJ, Zhou G
International journal of molecular sciences 2023 Sep 26;24(19)
International journal of molecular sciences 2023 Sep 26;24(19)
Long intergenic non-coding RNA DIO3OS promotes osteosarcoma metastasis via activation of the TGF-β signaling pathway: a potential diagnostic and immunotherapeutic target for osteosarcoma.
Yuan J, Jia J, Wu T, Du Z, Chen Q, Zhang J, Wu Z, Yuan Z, Zhao X, Liu J, Guo J, Cheng X
Cancer cell international 2023 Sep 26;23(1):215
Cancer cell international 2023 Sep 26;23(1):215
Combination of Kaempferol and Docetaxel Induces Autophagy in Prostate Cancer Cells In Vitro and In Vivo.
Zhou Q, Fang G, Pang Y, Wang X
International journal of molecular sciences 2023 Sep 25;24(19)
International journal of molecular sciences 2023 Sep 25;24(19)
SPI1-Mediated Upregulation of the CST1 Gene as an Independent Poor Prognostic Factor Accelerates Metastasis in Esophageal Squamous Cell Carcinoma (ESCC) by Interacting with MMP2.
Luo FF, Wang J, Zhang ZF, Lin ST, Huang TJ, Liu BQ, Fan ML, Peng LX, Zheng ST, Yang CF, Huang BJ
Frontiers in bioscience (Landmark edition) 2023 Sep 24;28(9):212
Frontiers in bioscience (Landmark edition) 2023 Sep 24;28(9):212
DSCC1 interacts with HSP90AB1 and promotes the progression of lung adenocarcinoma via regulating ER stress.
Lin X, Liu YH, Zhang HQ, Wu LW, Li Q, Deng J, Zhang Q, Yang Y, Zhang C, Li YL, Hu J
Cancer cell international 2023 Sep 23;23(1):208
Cancer cell international 2023 Sep 23;23(1):208
Methylation of BRD4 by PRMT1 regulates BRD4 phosphorylation and promotes ovarian cancer invasion.
Liu Y, Liu H, Ye M, Jiang M, Chen X, Song G, Ji H, Wang ZW, Zhu X
Cell death & disease 2023 Sep 22;14(9):624
Cell death & disease 2023 Sep 22;14(9):624
Characterization and optimization of variability in a human colonic epithelium culture model.
Pike CM, Zwarycz B, McQueen BE, Castillo M, Barron C, Morowitz JM, Levi JA, Phadke D, Balik-Meisner M, Mav D, Shah R, Glasspoole DLC, Laetham R, Thelin W, Bunger MK, Boazak EM
bioRxiv : the preprint server for biology 2023 Sep 22;
bioRxiv : the preprint server for biology 2023 Sep 22;
[Aumolertinib inhibits proliferation, invasion and migration and promotes apoptosis of neuroblastoma cells by downregulating MMP2 and MMP9 expression].
Liu X, Yang Y, Cai H, Zhang Y, Fan F, Li X, Li S
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Sep 20;43(9):1493-1499
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Sep 20;43(9):1493-1499
Pan-cancer analysis and experimental validation identify ndc1 as a potential immunological, prognostic and therapeutic biomarker in pancreatic cancer.
Shen Q, Li J, Zhang C, Pan X, Li Y, Zhang X, En G, Pang B
Aging 2023 Sep 20;15(18):9779-9796
Aging 2023 Sep 20;15(18):9779-9796
Progranulin promoted the proliferation, metastasis, and suppressed apoptosis via JAK2-STAT3/4 signaling pathway in papillary thyroid carcinoma.
Dong Y, Tan H, Wang L, Liu Z
Cancer cell international 2023 Sep 2;23(1):191
Cancer cell international 2023 Sep 2;23(1):191
Hypoxia-inducible factor upregulation by roxadustat attenuates drug reward by altering brain iron homoeostasis.
Yan P, Li N, Ma M, Liu Z, Yang H, Li J, Wan C, Gao S, Li S, Zheng L, Waddington JL, Xu L, Zhen X
Signal transduction and targeted therapy 2023 Sep 18;8(1):355
Signal transduction and targeted therapy 2023 Sep 18;8(1):355
Modified Gegen Qinlian decoction ameliorated ulcerative colitis by attenuating inflammation and oxidative stress and enhancing intestinal barrier function in vivo and in vitro.
Wang Y, Zhang J, Zhang B, Lu M, Ma J, Liu Z, Huang J, Ma J, Yang X, Wang F, Tang X
Journal of ethnopharmacology 2023 Sep 15;313:116538
Journal of ethnopharmacology 2023 Sep 15;313:116538
circAGTPBP1 promotes the progression of papillary thyroid cancer through the notch pathway via the miR-34a-5p/notch1 axis.
Dai L, Zhang W, Wang Y, Yu K, Le Q, Wu X
iScience 2023 Sep 15;26(9):107564
iScience 2023 Sep 15;26(9):107564
Nephroprotective Effects of Cardamonin on Renal Ischemia Reperfusion Injury/UUO-Induced Renal Fibrosis.
Zhang B, Chen ZY, Jiang Z, Huang S, Liu XH, Wang L
Journal of agricultural and food chemistry 2023 Sep 13;71(36):13284-13303
Journal of agricultural and food chemistry 2023 Sep 13;71(36):13284-13303
POFUT1 promotes gastric cancer progression through Notch/Wnt dual signaling pathways dependent on the parafibromin-NICD1-β-catenin complex.
Dong S, Wang Z, Xiong W
Journal of the Chinese Medical Association : JCMA 2023 Sep 1;86(9):806-817
Journal of the Chinese Medical Association : JCMA 2023 Sep 1;86(9):806-817
Shikonin suppresses small cell lung cancer growth via inducing ATF3-mediated ferroptosis to promote ROS accumulation.
Qian X, Zhu L, Xu M, Liu H, Yu X, Shao Q, Qin J
Chemico-biological interactions 2023 Sep 1;382:110588
Chemico-biological interactions 2023 Sep 1;382:110588
Distinct invasive patterns in situ between estrogen receptor-positive and triple-negative breast cancer through the intraductal tracking of carbon nanoparticles.
Kuang X, Luo Z, Sun Z, Hu J, Liu J, Kong D, Wang G, Guo L, Luo L, Zheng W, Sun S, Rao Y, Chen C
International journal of cancer 2023 Sep 1;153(5):1067-1079
International journal of cancer 2023 Sep 1;153(5):1067-1079
CircUSP10 promotes liver cancer progression by regulating miR-211-5p/TCF12/EMT signaling pathway.
Chen X, Xu Y, Zhou Z, Zhao P, Zhou Z, Wang F, Zhong F, Du H
Heliyon 2023 Oct;9(10):e20649
Heliyon 2023 Oct;9(10):e20649
ANKRD22 knockdown suppresses papillary thyroid cell carcinoma growth and migration and modulates the Wnt/β-catenin signaling pathway.
Wu Y, Chen W, Zhang B, Liu H
Tissue & cell 2023 Oct;84:102193
Tissue & cell 2023 Oct;84:102193
Pingxiao capsule inhibits lung metastasis of triple-negative breast cancer and sensitizes breast cancer to radiotherapy.
Wenjuan T, Yu HU, Man Z, Mingzhi D, Tieming L, Ammar S, Yingzhuan Z, Yanmin Z
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Oct;43(5):897-905
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Oct;43(5):897-905
Degradation of HIF-1α induced by curcumol blocks glutaminolysis and inhibits epithelial-mesenchymal transition and invasion in colorectal cancer cells.
Bian Y, Yin G, Wang G, Liu T, Liang L, Yang X, Zhang W, Tang D
Cell biology and toxicology 2023 Oct;39(5):1957-1978
Cell biology and toxicology 2023 Oct;39(5):1957-1978
Regulation of the stem‑like properties of estrogen receptor‑positive breast cancer cells through NR2E3/NR2C2 signaling.
Xie S, Hu Y, Jin J, Fu L, Zhang C, Yang Q, Niu Y, Sheng Z
Experimental and therapeutic medicine 2023 Oct;26(4):474
Experimental and therapeutic medicine 2023 Oct;26(4):474
Nrf3 promotes the proliferation and migration of triple‑negative breast cancer by activating PI3K/AKT/mTOR and epithelial‑mesenchymal transition.
Chen WM, Hu QY, Hou W, Chen MW, Chen YH, Tang JC
Oncology letters 2023 Oct;26(4):443
Oncology letters 2023 Oct;26(4):443
ACLY promotes gastric tumorigenesis and accelerates peritoneal metastasis of gastric cancer regulated by HIF-1A.
Yan Z, Liu K, Xu P, Chen Z, Zhang P, Pei S, Cheng Q, Huang S, Li B, Lv J, Xu Z, Xu H, Yang L, Zhang D
Cell cycle (Georgetown, Tex.) 2023 Oct;22(20):2288-2301
Cell cycle (Georgetown, Tex.) 2023 Oct;22(20):2288-2301
IGF2BP2 promotes glycolysis and hepatocellular carcinoma stemness by stabilizing CDC45 mRNA via m6A modification.
Wu T, Liao L, Wu T, Chen S, Yi Q, Xu M
Cell cycle (Georgetown, Tex.) 2023 Oct;22(20):2245-2263
Cell cycle (Georgetown, Tex.) 2023 Oct;22(20):2245-2263
Knockdown of ABHD11‑AS1 prevents the procession of TNBC by upregulating miR‑199a‑5p.
Dong Y, Zhang T, Shao S, Li X, Jiang P, Guo Y, Gu D
Biomedical reports 2023 Oct;19(4):69
Biomedical reports 2023 Oct;19(4):69
Lemur tyrosine kinase 2 has a tumor-inhibition function in human glioblastoma by regulating the RUNX3/Notch pathway.
Zhang L, Luo P, Mao X, Sun J, Wei J, Yang Y, Zhang Y, Jiang X
Biochimica et biophysica acta. Molecular cell research 2023 Oct;1870(7):119509
Biochimica et biophysica acta. Molecular cell research 2023 Oct;1870(7):119509
Ampelopsin attenuates Staphylococcus aureus Alpha-Toxin-Induced Lung Injury.
Wang Y, Tang M, Deng H, Hong Z, Liang Z, Huang Y, Zeng C, Yang K
Microbial pathogenesis 2023 Oct;183:106316
Microbial pathogenesis 2023 Oct;183:106316
Nintedanib inhibits normal human vitreous-induced epithelial-mesenchymal transition in human retinal pigment epithelial cells.
Yin Y, Liu S, Liu H, Wu W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115403
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115403
Discovery of small molecule β-catenin suppressors that enhance immunotherapy.
Feng X, Ge J, Fu H, Miao L, Zhao F, Wang J, Sun Y, Li Y, Li Y
Bioorganic chemistry 2023 Oct;139:106754
Bioorganic chemistry 2023 Oct;139:106754
UBE2V2 promotes metastasis by regulating EMT and predicts a poor prognosis in lung adenocarcinoma.
Yang Z, Wu G, Zhao J, Shi G, Zhou J, Zhou X
Cancer medicine 2023 Oct;12(19):19850-19865
Cancer medicine 2023 Oct;12(19):19850-19865
Role of Nucleobindin-2 in the Clinical Pathogenesis and Treatment Resistance of Glioblastoma.
Lin IC, Chang CH, Chong YB, Kuo SH, Cheng YW, Lieu AS, Tseng TT, Lin CJ, Tsai HP, Kwan AL
Cells 2023 Oct 9;12(19)
Cells 2023 Oct 9;12(19)
Placenta mesenchymal stem cell-derived extracellular vesicles alleviate liver fibrosis by inactivating hepatic stellate cells through a miR-378c/SKP2 axis.
Zheng W, Bian S, Qiu S, Bishop CE, Wan M, Xu N, Sun X, Sequeira RC, Atala A, Gu Z, Zhao W
Inflammation and regeneration 2023 Oct 5;43(1):47
Inflammation and regeneration 2023 Oct 5;43(1):47
Fu-Zheng-Tong-Luo formula promotes autophagy and alleviates idiopathic pulmonary fibrosis by controlling the Janus kinase 2/signal transducer and activator of transcription 3 pathway.
Zhang X, Su J, Lin J, Liu L, Wu J, Yuan W, Zhang Y, Chen Q, Su ZJ, Xu G, Sun M, Zhang Y, Chen X, Zhang W
Journal of ethnopharmacology 2023 Oct 5;314:116633
Journal of ethnopharmacology 2023 Oct 5;314:116633
Xue-Jie-San prevents the early development of colitis-associated intestinal fibrosis by blocking Notch1 and FGL1 signaling pathways.
Gao Y, Lu LJ, Zhang ZZ, Yang X, Du J, Wen K, Huang H, Wang XP, Sun XL
Journal of ethnopharmacology 2023 Oct 28;315:116678
Journal of ethnopharmacology 2023 Oct 28;315:116678
Dynamic interactions between E-cadherin and Ankyrin-G mediate epithelial cell polarity maintenance.
Kong C, Qu X, Liu M, Xu W, Chen D, Zhang Y, Zhang S, Zhu F, Liu Z, Li J, Huang C, Wang C
Nature communications 2023 Oct 27;14(1):6860
Nature communications 2023 Oct 27;14(1):6860
CRTC2 activates the epithelial-mesenchymal transition of diabetic kidney disease through the CREB-Smad2/3 pathway.
Li Y, Zhang Y, Shi H, Liu X, Li Z, Zhang J, Wang X, Wang W, Tong X
Molecular medicine (Cambridge, Mass.) 2023 Oct 26;29(1):146
Molecular medicine (Cambridge, Mass.) 2023 Oct 26;29(1):146
Gut Bacterial Community Determines the Therapeutic Effect of Ginsenoside on Canine Inflammatory Bowel Disease by Modulating the Colonic Mucosal Barrier.
Mao A, Zhao W, Zhu Y, Kong F, Chen D, Si H, Xu C
Microorganisms 2023 Oct 24;11(11)
Microorganisms 2023 Oct 24;11(11)
Minichromosome maintenance 6 protects against renal fibrogenesis by regulating DUSP6-mediated ERK/GSK-3β/Snail1 signaling.
Huang J, Xu ZF, Liu F, Song AN, Su H, Zhang C
iScience 2023 Oct 20;26(10):107940
iScience 2023 Oct 20;26(10):107940
High glucose promotes benign prostatic hyperplasia by downregulating PDK4 expression.
Wei P, Lin D, Luo C, Zhang M, Deng B, Cui K, Chen Z
Scientific reports 2023 Oct 20;13(1):17910
Scientific reports 2023 Oct 20;13(1):17910
CYP19A1 promotes gastric cancer as part of a lipid metabolism-related gene signature related to the response of immunotherapy and prognosis.
Zhou X, Meng F, Xiao L, Shen H
BMC medical genomics 2023 Oct 2;16(1):228
BMC medical genomics 2023 Oct 2;16(1):228
Eriocitrin inhibits epithelial-mesenchymal transformation (EMT) in lung adenocarcinoma cells via triggering ferroptosis.
Gao M, Lai K, Deng Y, Lu Z, Song C, Wang W, Xu C, Li N, Geng Q
Aging 2023 Oct 2;15(19):10089-10104
Aging 2023 Oct 2;15(19):10089-10104
USP53 Exerts Tumor-Promoting Effects in Triple-Negative Breast Cancer by Deubiquitinating CRKL.
Liu Y, Tang W, Yao F
Cancers 2023 Oct 18;15(20)
Cancers 2023 Oct 18;15(20)
PM(2.5) induces renal tubular injury by activating NLRP3-mediated pyroptosis.
Chen W, Luo Y, Quan J, Zhou J, Yi B, Huang Z
Ecotoxicology and environmental safety 2023 Oct 15;265:115490
Ecotoxicology and environmental safety 2023 Oct 15;265:115490
Dendrobium officinale polysaccharide Converts M2 into M1 Subtype Macrophage Polarization via the STAT6/PPAR-r and JAGGED1/NOTCH1 Signaling Pathways to Inhibit Gastric Cancer.
Zhao Y, Lu X, Huang H, Yao Y, Liu H, Sun Y
Molecules (Basel, Switzerland) 2023 Oct 12;28(20)
Molecules (Basel, Switzerland) 2023 Oct 12;28(20)
A pan-cancer analysis of the role of HOXD1, HOXD3, and HOXD4 and validation in renal cell carcinoma.
Wang L, Wang X, Sun H, Wang W, Cao L
Aging 2023 Oct 12;15(19):10746-10766
Aging 2023 Oct 12;15(19):10746-10766
Fucoidan/chitosan layered PLGA nanoparticles with melatonin loading for inducing intestinal absorption and addressing triple-negative breast cancer progression.
Yen YW, Lee YL, Yu LY, Li CE, Shueng PW, Chiu HC, Lo CL
International journal of biological macromolecules 2023 Oct 1;250:126211
International journal of biological macromolecules 2023 Oct 1;250:126211
Exploring the anticancer potential of Actinidia chinensis Planch root extracts (acRoots) on hepatocellular carcinoma: A molecular mechanism study.
Qiu K, Xia Q, Chen H, Ye Q, Mao H, Tian M, Gan Y, Huang Q, Wang H, Duan S
Heliyon 2023 Nov;9(11):e21851
Heliyon 2023 Nov;9(11):e21851
TRIM16 E121D variant affects the risk and prognosis of hepatocellular carcinoma by modulating the Wnt/β-catenin pathway.
Li S, Wang J, Chen H, Hou J, Shen T, Li J, Zhou B, Zhang B, Liu H, Jiang DK
Molecular carcinogenesis 2023 Nov;62(11):1686-1699
Molecular carcinogenesis 2023 Nov;62(11):1686-1699
Circ_0001589/miR-1248/HMGB1 axis enhances EMT-mediated metastasis and cisplatin resistance in cervical cancer.
Ma T, Guo J, Han J, Li L, Ren Y, Huang J, Diao G, Zheng X, Zheng Y
Molecular carcinogenesis 2023 Nov;62(11):1645-1658
Molecular carcinogenesis 2023 Nov;62(11):1645-1658
Macrophage microvesicle-derived circ_YTHDF2 in methamphetamine-induced chronic lung injury.
Chen L, Gu YJ, Zhang XG, Cheng L, Zhou MY, Yang Y, Wang Y
The Journal of physiology 2023 Nov;601(22):5107-5128
The Journal of physiology 2023 Nov;601(22):5107-5128
BMP4 Regulates EMT to be Involved in non-Syndromic Cleft lip With or Without Palate.
Hong JW, Yu Y, Wang LS, Li Z, Zhang R, Wang Q, Ding Z, Zhang JP, Zhang MR, Xu LC
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 2023 Nov;60(11):1462-1473
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 2023 Nov;60(11):1462-1473
RNA‑binding protein quaking 5 inhibits the progression of non‑small cell lung cancer by upregulating netrin‑4 expression.
Wu Z, Liu S, Pang G, Jiang H
Oncology reports 2023 Nov;50(5)
Oncology reports 2023 Nov;50(5)
Inhibition of TMEM16A improves cisplatin-induced acute kidney injury via preventing DRP1-mediated mitochondrial fission.
Li XL, Liu XW, Liu WL, Lin YQ, Liu J, Peng YS, Cheng LM, Du YH
Acta pharmacologica Sinica 2023 Nov;44(11):2230-2242
Acta pharmacologica Sinica 2023 Nov;44(11):2230-2242
PAR2 deficiency tunes inflammatory microenvironment to magnify STING signalling for mitigating cancer metastasis via anionic CRISPR/Cas9 nanoparticles.
Fu X, Li J, Wu Y, Mao C, Jiang Y
Journal of controlled release : official journal of the Controlled Release Society 2023 Nov;363:733-746
Journal of controlled release : official journal of the Controlled Release Society 2023 Nov;363:733-746
PCSK9 promotes tumor cell proliferation and migration by facilitating CCL25 secretion in esophageal squamous cell carcinoma.
Wang H, Guo Q, Wang M, Liu C, Tian Z
Oncology letters 2023 Nov;26(5):500
Oncology letters 2023 Nov;26(5):500
B4GALNT1 promotes carcinogenesis by regulating epithelial-mesenchymal transition in hepatocellular carcinoma based on pan-cancer analysis.
Liu W, Chen Y, Yang J, Guo M, Wang L
The journal of gene medicine 2023 Nov;25(11):e3552
The journal of gene medicine 2023 Nov;25(11):e3552
Dauricine regulates prostate cancer progression by inhibiting PI3K/AKT-dependent M2 polarization of macrophages.
Li M, Che N, Liu X, Xuan Y, Jin Y
Biochemical pharmacology 2023 Nov;217:115838
Biochemical pharmacology 2023 Nov;217:115838
Hyperbranched polyamidoamine-RGD peptide/si-circICA1 in the treatment of invasive thyroid cancer through targeting of the miR-486-3p/SERPINA1 axis.
Dong S, Xia Q, Pan J, Du XL, Wu YJ, Xie XJ
Nanomedicine (London, England) 2023 Nov;18(27):2039-2059
Nanomedicine (London, England) 2023 Nov;18(27):2039-2059
CTRP6 regulates M1 macrophage polarization via the PPAR-γ/NF-κB pathway and reprogramming glycolysis in recurrent spontaneous abortion.
Yan S, Ding J, Wang Z, Zhang F, Li J, Zhang Y, Wu S, Yang L, Pang X, Zhang Y, Yang J
International immunopharmacology 2023 Nov;124(Pt A):110840
International immunopharmacology 2023 Nov;124(Pt A):110840
Icaritin inhibits endometrial carcinoma cells by suppressing O-GlcNAcylation of FOXC1.
Wang Y, Wang G, Liu Y, Yang F, Zhang H, Kong Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155062
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Nov;120:155062
Schisandrin B Alleviates Renal Tubular Cell Epithelial-Mesenchymal Transition and Mitochondrial Dysfunction by Kielin/Chordin-like Protein Upregulation via Akt Pathway Inactivation and Adenosine 5'-Monophosphate (AMP)-Activated Protein Kinase Pathway Activation in Diabetic Kidney Disease.
Liu W, Li F, Guo D, Du C, Zhao S, Li J, Yan Z, Hao J
Molecules (Basel, Switzerland) 2023 Nov 29;28(23)
Molecules (Basel, Switzerland) 2023 Nov 29;28(23)
NF-κB downstream miR-1262 disturbs colon cancer cell malignant behaviors by targeting FGFR1.
Zhang W, Huang Z, Xiao Z, Wang H, Liao Q, Deng Z, Wu D, Wang J, Li Y
Acta biochimica et biophysica Sinica 2023 Nov 25;55(11):1819-1832
Acta biochimica et biophysica Sinica 2023 Nov 25;55(11):1819-1832
LMP2 and TAP2 impair tumor growth and metastasis by inhibiting Wnt/β-catenin signaling pathway and EMT in cervical cancer.
Cheng Z, Wang H, Yang Z, Li J, Chen X
BMC cancer 2023 Nov 20;23(1):1128
BMC cancer 2023 Nov 20;23(1):1128
FAM171B stabilizes vimentin and enhances CCL2-mediated TAM infiltration to promote bladder cancer progression.
Hu WM, Li M, Ning JZ, Tang YQ, Song TB, Li LZ, Zou F, Cheng F, Yu WM
Journal of experimental & clinical cancer research : CR 2023 Nov 2;42(1):290
Journal of experimental & clinical cancer research : CR 2023 Nov 2;42(1):290
Decreased fucosylation impacts epithelial integrity and increases risk for COPD.
Swaby C, Yeung-Luk B, Thapa S, Nishida K, Wally A, Ghosh B, Niederkofler A, Luk S, Girgis M, Keller A, Cortez C, Ramaswamy S, Wilmsen K, Bouché L, Dell A, Drummond MB, Putcha N, Haslam SM, Mathias R, Hansel NN, Sheng J, Sidhaye V
bioRxiv : the preprint server for biology 2023 Nov 2;
bioRxiv : the preprint server for biology 2023 Nov 2;
MircroRNA-92b as a negative regulator of the TGF-β signaling by targeting the type I receptor.
Yang S, Jiang K, Li L, Xiang J, Li Y, Kang L, Yang G, Liang Z
iScience 2023 Nov 17;26(11):108131
iScience 2023 Nov 17;26(11):108131
Curcumin Disrupts a Positive Feedback Loop between ADMSCs and Cancer Cells in the Breast Tumor Microenvironment via the CXCL12/CXCR4 Axis.
Jang BY, Shin MK, Han DH, Sung JS
Pharmaceutics 2023 Nov 15;15(11)
Pharmaceutics 2023 Nov 15;15(11)
LASS2 enhances p53 protein stability and nuclear import to suppress liver cancer progression through interaction with MDM2/MDMX.
Zhao Q, He W, Liu Z, Huang L, Yang X, Liu Y, Chen R, Min X, Yang Y
Cell death discovery 2023 Nov 14;9(1):414
Cell death discovery 2023 Nov 14;9(1):414
IGFBP2 drives epithelial-mesenchymal transition in hepatocellular carcinoma via activating the Wnt/β-catenin pathway.
Chen X, Zhang Y, Zhang P, Wei M, Tian T, Guan Y, Han C, Wei W, Ma Y
Infectious agents and cancer 2023 Nov 13;18(1):73
Infectious agents and cancer 2023 Nov 13;18(1):73
GAD1-mediated GABA elicits aggressive characteristics of human oral cancer cells.
Dou Z, Li M, Shen Z, Jiang H, Pang X, Li T, Liang X, Tang Y
Biochemical and biophysical research communications 2023 Nov 12;681:80-89
Biochemical and biophysical research communications 2023 Nov 12;681:80-89
Lnc AC016727.1/BACH1/HIF-1 α signal loop promotes the progression of non-small cell lung cancer.
Zhang L, Liang J, Qin H, Lv Y, Liu X, Li Z, Chao Z, Jia C, Qin X, Zhang H
Journal of experimental & clinical cancer research : CR 2023 Nov 10;42(1):296
Journal of experimental & clinical cancer research : CR 2023 Nov 10;42(1):296
The HDAC inhibitor HFY-4A improves TUSC2 transcription to induce immunogenic cell death in breast cancer.
Yin Y, Guan X, Li G, Chen C, Duan Y, Yu Z
Toxicology and applied pharmacology 2023 Nov 1;478:116698
Toxicology and applied pharmacology 2023 Nov 1;478:116698
Piezoeletric cold atmospheric plasma induces apoptosis and autophagy in human hepatocellular carcinoma cells through blocking glycolysis and AKT/mTOR/HIF-1α pathway.
Wang Y, Mang X, Li D, Chen Y, Cai Z, Tan F
Free radical biology & medicine 2023 Nov 1;208:134-152
Free radical biology & medicine 2023 Nov 1;208:134-152
Suprabasin enhances the invasion, migration, and angiogenic ability of oral squamous cell carcinoma cells under hypoxic conditions.
Houri A, Mukudai Y, Abe Y, Watanabe M, Nara M, Miyamoto S, Kurihara M, Shimane T, Shirota T
Oncology reports 2023 May;49(5)
Oncology reports 2023 May;49(5)
Alpha lipoamide inhibits diabetic kidney fibrosis via improving mitochondrial function and regulating RXRα expression and activation.
Zhang HF, Liu HM, Xiang JY, Zhou XC, Wang D, Chen RY, Tan WL, Liang LQ, Liu LL, Shi MJ, Zhang F, Xiao Y, Zhou YX, Zhang T, Tang L, Guo B, Wang YY
Acta pharmacologica Sinica 2023 May;44(5):1051-1065
Acta pharmacologica Sinica 2023 May;44(5):1051-1065
CircRNA_0017076 acts as a sponge for miR-185-5p in the control of epithelial-to-mesenchymal transition of tubular epithelial cells during renal interstitial fibrosis.
Zhang F, Zou H, Li X, Liu J, Xie Y, Chen M, Yu J, Wu X, Guo B
Human cell 2023 May;36(3):1024-1040
Human cell 2023 May;36(3):1024-1040
Retinoic acid-loaded PLGA nanocarriers targeting cell cholesterol potentialize the antitumour effect of PD-L1 antibody by preventing epithelial-mesenchymal transition mediated by M2-TAM in colorectal cancer.
Júnior RFA, Lira GA, Schomann T, Cavalcante RS, Vilar NF, de Paula RCM, Gomes RF, Chung CK, Jorquera-Cordero C, Vepris O, Chan AB, Cruz LJ
Translational oncology 2023 May;31:101647
Translational oncology 2023 May;31:101647
ADAM12 promotes gemcitabine resistance by activating EGFR signaling pathway and induces EMT in bladder cancer.
Wang R, Gao D, Chen C, Fan G, Cheng H, Tao Y, Lu J, Tian J, Wang Y, Wang Z
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 May;25(5):1425-1435
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 May;25(5):1425-1435
CircRNA OXCT1 promotes the malignant progression and glutamine metabolism of non-small cell lung cancer by absorbing miR-516b-5p and upregulating SLC1A5.
Luo H, Peng J, Yuan Y
Cell cycle (Georgetown, Tex.) 2023 May;22(10):1182-1195
Cell cycle (Georgetown, Tex.) 2023 May;22(10):1182-1195
Nicotine exposure exacerbates silica-induced pulmonary fibrosis via STAT3-BDNF-TrkB-mediated epithelial-mesenchymal transition in alveolar type II cells.
Chen H, Tao X, Cao H, Li B, Sun Q, Wang W, Zou Y, Mu M, Tao H, Zhao Y, Ge D
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 May;175:113694
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 May;175:113694
Nintedanib prevents TGF-β2-induced epithelial-mesenchymal transition in retinal pigment epithelial cells.
Yin Y, Liu S, Pu L, Luo J, Liu H, Wu W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114543
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114543
Extracellular vesicles derived from Akkermansia muciniphila promote placentation and mitigate preeclampsia in a mouse model.
Chen Y, Ou Z, Pang M, Tao Z, Zheng X, Huang Z, Wen D, Li Q, Zhou R, Chen P, Situ B, Sheng C, Huang Y, Yue X, Zheng L, Huang L
Journal of extracellular vesicles 2023 May;12(5):e12328
Journal of extracellular vesicles 2023 May;12(5):e12328
BZW1 as an oncogene is associated with patient prognosis and the immune microenvironment in glioma.
Zhao L, Song C, Li Y, Yuan F, Zhao Q, Dong H, Liu B
Genomics 2023 May;115(3):110602
Genomics 2023 May;115(3):110602
The NR_109/FUBP1/c-Myc axis regulates TAM polarization and remodels the tumor microenvironment to promote cancer development.
Zhang C, Wei S, Dai S, Li X, Wang H, Zhang H, Sun G, Shan B, Zhao L
Journal for immunotherapy of cancer 2023 May;11(5)
Journal for immunotherapy of cancer 2023 May;11(5)
MicroRNA-150-5p inhibits the proliferation and invasion of human larynx epidermiod cancer cells though regulating peptidyl-prolyl cis/trans isomerase.
Chen H, Cai X, Du B, Cai J, Luo Z
Brazilian journal of otorhinolaryngology 2023 May-Jun;89(3):383-392
Brazilian journal of otorhinolaryngology 2023 May-Jun;89(3):383-392
miR-137-LAPTM4B regulates cytoskeleton organization and cancer metastasis via the RhoA-LIMK-Cofilin pathway in osteosarcoma.
Yan R, Liu D, Wang J, Liu M, Guo H, Bai J, Yang S, Chang J, Yao Z, Yang Z, Blom T, Zhou K
Oncogenesis 2023 May 6;12(1):25
Oncogenesis 2023 May 6;12(1):25
Effects of Therapeutic Platelet-Rich Plasma on Overactive Bladder via Modulating Hyaluronan Synthesis in Ovariectomized Rat.
Lu JH, Chueh KS, Juan TJ, Mao JW, Lin RJ, Lee YC, Shen MC, Sun TW, Lin HY, Juan YS
International journal of molecular sciences 2023 May 4;24(9)
International journal of molecular sciences 2023 May 4;24(9)
Suppression of TGFβR-Smad3 pathway alleviates the syrinx induced by syringomyelia.
Liu S, Ma L, Qi B, Li Q, Chen Z, Jian F
Cell & bioscience 2023 May 29;13(1):98
Cell & bioscience 2023 May 29;13(1):98
High Level of GMFG Correlated to Poor Clinical Outcome and Promoted Cell Migration and Invasion through EMT Pathway in Triple-Negative Breast Cancer.
Zhao Y, Wei X, Li J, Diao Y, Shan C, Li W, Zhang S, Wu F
Genes 2023 May 26;14(6)
Genes 2023 May 26;14(6)
Rhein Inhibited Ferroptosis and EMT to Attenuate Diabetic Nephropathy by Regulating the Rac1/NOX1/β-Catenin Axis.
Xiong D, Hu W, Han X, Cai Y
Frontiers in bioscience (Landmark edition) 2023 May 25;28(5):100
Frontiers in bioscience (Landmark edition) 2023 May 25;28(5):100
The mediation of the AHR/IL-22/STAT3/IL-6 axis by soft-shelled turtle (Pelodiscus sinensis) peptide and Chinese pond turtle (Chinemys reevesii) peptide contributed to their amelioration effects on intestinal mucosal immunity in immunosuppressed mice.
Zhuang J, Wang Q, Shen F, Wang J, Du J, Yu P, Feng F, Zhao M
Food & function 2023 May 22;14(10):4681-4695
Food & function 2023 May 22;14(10):4681-4695
CEBPG suppresses ferroptosis through transcriptional control of SLC7A11 in ovarian cancer.
Zhang X, Zheng X, Ying X, Xie W, Yin Y, Wang X
Journal of translational medicine 2023 May 20;21(1):334
Journal of translational medicine 2023 May 20;21(1):334
Alterations in histology of the aging salivary gland and correlation with the glandular inflammatory microenvironment.
Li N, Ye Y, Wu Y, Li L, Hu J, Luo D, Li Y, Yang J, Gao Y, Hai W, Xie Y, Jiang L
iScience 2023 May 19;26(5):106571
iScience 2023 May 19;26(5):106571
USP22 aggravated diabetic renal tubulointerstitial fibrosis progression through deubiquitinating and stabilizing Snail1.
Zhao X, He X, Wei W, Huang K
European journal of pharmacology 2023 May 15;947:175671
European journal of pharmacology 2023 May 15;947:175671
Guanine nucleotide exchange factor T exerts the cancer-promoting function in cholangiocarcinoma by enhancing the Wnt-GSK-3β-β-catenin cascade via regulation of Rac1/Cdc42.
Wang X, Zhang X, Sun J, Sun Y, Zhang Y, He L, Wang P, Li F, Sun C
Toxicology and applied pharmacology 2023 May 15;467:116492
Toxicology and applied pharmacology 2023 May 15;467:116492
PRMT2 promotes RCC tumorigenesis and metastasis via enhancing WNT5A transcriptional expression.
Li Z, Chen C, Yong H, Jiang L, Wang P, Meng S, Chu S, Li Z, Guo Q, Zheng J, Bai J, Li H
Cell death & disease 2023 May 12;14(5):322
Cell death & disease 2023 May 12;14(5):322
Yishen Tongluo formula alleviates diabetic kidney disease through regulating Sirt6/TGF-β1/Smad2/3 pathway and promoting degradation of TGF-β1.
Zhang X, Zhao L, Xiang S, Sun Y, Wang P, Chen JJ, Teo BS, Xie Z, Zhang Z, Xu J
Journal of ethnopharmacology 2023 May 10;307:116243
Journal of ethnopharmacology 2023 May 10;307:116243
Growth and Migration Blocking Effect of Nanaomycin K, a Compound Produced by Streptomyces sp., on Prostate Cancer Cell Lines In Vitro and In Vivo.
Hirata Y, Shigemura K, Moriwaki M, Iwatsuki M, Kan Y, Ooya T, Maeda K, Yang Y, Nakashima T, Matsuo H, Nakanishi J, Fujisawa M
Cancers 2023 May 10;15(10)
Cancers 2023 May 10;15(10)
Metrnl Alleviates Lipid Accumulation by Modulating Mitochondrial Homeostasis in Diabetic Nephropathy.
Zhou Y, Liu L, Jin B, Wu Y, Xu L, Chang X, Hu L, Wang G, Huang Y, Song L, Zhang T, Wang Y, Xiao Y, Zhang F, Shi M, Liu L, Wang T, Yan R, Guo B
Diabetes 2023 May 1;72(5):611-626
Diabetes 2023 May 1;72(5):611-626
Decreasing expression of Prohibitin-2 lowers the oncogenicity of renal cell carcinoma cells by suppressing eIF4E-mediated oncogene translation via MNK inhibition.
Yang J, Li G, Huang Y, Liu Y
Toxicology and applied pharmacology 2023 May 1;466:116458
Toxicology and applied pharmacology 2023 May 1;466:116458
KIFC3 regulates progression of hepatocellular carcinoma via EMT and the AKT/mTOR pathway.
Lu S, Liu Y, Tian S, He Y, Dong W
Experimental cell research 2023 May 1;426(1):113564
Experimental cell research 2023 May 1;426(1):113564
Salt-like transcription factor 4 promotes laryngeal cancer progression through transcriptional activation of ubiquitin-specific protease 21 to stabilize Yin Yang 1.
Wang QD, Liu LL, Li D, Gao L, Zhang MJ
Pathology international 2023 Mar;73(3):109-119
Pathology international 2023 Mar;73(3):109-119
Thiol oxidative stress-dependent degradation of transglutaminase2 via protein S-glutathionylation sensitizes 5-fluorouracil therapy in 5-fluorouracil-resistant colorectal cancer cells.
Li X, Ma Y, Wu J, Ni M, Chen A, Zhou Y, Dai W, Chen Z, Jiang R, Ling Y, Yao Q, Chen W
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2023 Mar;67:100930
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2023 Mar;67:100930
MiR-29a-3p inhibits high-grade transformation and epithelial-mesenchymal transition of lacrimal gland adenoid cystic carcinoma by targeting Quaking.
Xu F, Jiang M, Tang Q, Lin J, Liu X, Zhang C, Zhao J, He Y, Dong L, Zhu L, Lin T
Molecular biology reports 2023 Mar;50(3):2305-2316
Molecular biology reports 2023 Mar;50(3):2305-2316
Exosomes from tubular epithelial cells undergoing epithelial-to-mesenchymal transition promote renal fibrosis by M1 macrophage activation.
Lu Y, Zhang R, Gu X, Wang X, Xi P, Chen X
FASEB bioAdvances 2023 Mar;5(3):101-113
FASEB bioAdvances 2023 Mar;5(3):101-113
miR‑151a‑5p promotes the proliferation and metastasis of colorectal carcinoma cells by targeting AGMAT.
Xie Y, Zhang Y, Liu X, Cao L, Han M, Wang C, Chen J, Zhang X
Oncology reports 2023 Mar;49(3)
Oncology reports 2023 Mar;49(3)
The role of interleukin 36γ in the epithelial-mesenchymal transition process of chronic rhinosinusitis: A pilot study.
Shen LF, Chen HH, Guo Y
Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery 2023 Mar;48(2):347-355
Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery 2023 Mar;48(2):347-355
Circ_0056618 enhances PRRG4 expression by competitively binding to miR-411-5p to promote the malignant progression of colorectal cancer.
Zhang B, Cao W, Liu Y, Zhao Y, Liu C, Sun B
Molecular and cellular biochemistry 2023 Mar;478(3):503-516
Molecular and cellular biochemistry 2023 Mar;478(3):503-516
RASSF1A inhibits epithelial-mesenchymal transition of gastric cancer cells by downregulating P-JNK.
Bin Y, Deng W, Hu H, Zeng Q, Chen J, Xu Y, Dai Y, Liao A, Xiao W
Cell biology international 2023 Mar;47(3):573-583
Cell biology international 2023 Mar;47(3):573-583
CircNFIX stimulates the proliferation, invasion, and stemness properties of ovarian cancer cells by enhancing SH3RF3 mRNA stability via binding LIN28B.
Yu XZ, Yang BW, Ao MY, Wu YK, Ye H, Wang RY, Xi MR, Hou MM
The Kaohsiung journal of medical sciences 2023 Mar;39(3):234-243
The Kaohsiung journal of medical sciences 2023 Mar;39(3):234-243
Silencing RPL8 inhibits the progression of hepatocellular carcinoma by down-regulating the mTORC1 signalling pathway.
Sun T, Zhu W, Ru Q, Zheng Y
Human cell 2023 Mar;36(2):725-737
Human cell 2023 Mar;36(2):725-737
Immunity-related long noncoding RNA WDFY3-AS2 inhibited cell proliferation and metastasis through Wnt/β-catenin signaling in oral squamous cell carcinoma.
Lin X, Ding JM, Zheng XZ, Chen JG
Archives of oral biology 2023 Mar;147:105625
Archives of oral biology 2023 Mar;147:105625
Cyclin-dependent kinase subunit2 (CKS2) promotes malignant phenotypes and epithelial-mesenchymal transition-like process in glioma by activating TGFβ/SMAD signaling.
Feng F, Zhao Z, Cai X, Heng X, Ma X
Cancer medicine 2023 Mar;12(5):5889-5907
Cancer medicine 2023 Mar;12(5):5889-5907
Aspartame consumption during pregnancy impairs placenta growth in mice through sweet taste receptor-reactive oxygen species-dependent pathway.
Huang SY, Sun R, Chen YC, Kang L, Wang CT, Chiu CF, Wu HT
The Journal of nutritional biochemistry 2023 Mar;113:109228
The Journal of nutritional biochemistry 2023 Mar;113:109228
1,25(OH)(2) D(3) induced vitamin D receptor signaling negatively regulates endoplasmic reticulum-associated degradation (ERAD) and androgen receptor signaling in human prostate cancer cells.
Erzurumlu Y, Aydogdu E, Dogan HK, Catakli D, Muhammed MT, Buyuksandic B
Cellular signalling 2023 Mar;103:110577
Cellular signalling 2023 Mar;103:110577
NETs Promote Inflammatory Injury by Activating cGAS-STING Pathway in Acute Lung Injury.
Zhao J, Zhen N, Zhou Q, Lou J, Cui W, Zhang G, Tian B
International journal of molecular sciences 2023 Mar 7;24(6)
International journal of molecular sciences 2023 Mar 7;24(6)
The Enzyme 15-Hydroxyprostaglandin Dehydrogenase Inhibits a Shift to the Mesenchymal Pattern of Trophoblasts and Decidual Stromal Cells Accompanied by Prostaglandin Transporter in Preeclampsia.
Pang H, Lei D, Chen T, Liu Y, Fan C
International journal of molecular sciences 2023 Mar 7;24(6)
International journal of molecular sciences 2023 Mar 7;24(6)
HSPA5 Promotes the Proliferation, Metastasis and Regulates Ferroptosis of Bladder Cancer.
Wang Q, Ke S, Liu Z, Shao H, He M, Guo J
International journal of molecular sciences 2023 Mar 7;24(6)
International journal of molecular sciences 2023 Mar 7;24(6)
SEMA6C: a novel adhesion-independent FAK and YAP activator, required for cancer cell viability and growth.
Fard D, Testa E, Panzeri V, Rizzolio S, Bianchetti G, Napolitano V, Masciarelli S, Fazi F, Maulucci G, Scicchitano BM, Sette C, Viscomi MT, Tamagnone L
Cellular and molecular life sciences : CMLS 2023 Mar 31;80(4):111
Cellular and molecular life sciences : CMLS 2023 Mar 31;80(4):111
CPT1A modulates PI3K/Akt/mTOR pathway to promote preeclampsia.
Chen M, Chao B, Xu J, Liu Z, Tao Y, He J, Wang J, Yang H, Luo X, Qi H
Placenta 2023 Mar 3;133:23-31
Placenta 2023 Mar 3;133:23-31
Demethylase FTO enhances the PI3K/Akt signaling to promote gastric cancer malignancy.
Zhu Y, Yang J, Li Y, Xu J, Fang Z
Medical oncology (Northwood, London, England) 2023 Mar 27;40(5):130
Medical oncology (Northwood, London, England) 2023 Mar 27;40(5):130
Fatostatin induces ferroptosis through inhibition of the AKT/mTORC1/GPX4 signaling pathway in glioblastoma.
Cai J, Ye Z, Hu Y, Ye L, Gao L, Wang Y, Sun Q, Tong S, Zhang S, Wu L, Yang J, Chen Q
Cell death & disease 2023 Mar 25;14(3):211
Cell death & disease 2023 Mar 25;14(3):211
NONHSAT021545/miR-330-3p/EREG: A Cooperative Axis in Breast Cancer Prognosis and Treatment.
Zhang Y, Guo C, Yang S, Elkharti M, Liu R, Sun MZ, Liu S
Journal of clinical medicine 2023 Mar 24;12(7)
Journal of clinical medicine 2023 Mar 24;12(7)
Discovery of Potent DYRK2 Inhibitors with High Selectivity, Great Solubility, and Excellent Safety Properties for the Treatment of Prostate Cancer.
Yuan K, Shen H, Zheng M, Xia F, Li Q, Chen W, Ji M, Yang H, Zhuang X, Cai Z, Min W, Wang X, Xiao Y, Yang P
Journal of medicinal chemistry 2023 Mar 23;66(6):4215-4230
Journal of medicinal chemistry 2023 Mar 23;66(6):4215-4230
Receptor tyrosine kinase C-kit promotes a destructive phenotype of FLS in osteoarthritis via intracellular EMT signaling.
Cao X, Wu S, Wang X, Huang J, Zhang W, Liang C
Molecular medicine (Cambridge, Mass.) 2023 Mar 23;29(1):38
Molecular medicine (Cambridge, Mass.) 2023 Mar 23;29(1):38
SEPT2 crotonylation promotes metastasis and recurrence in hepatocellular carcinoma and is associated with poor survival.
Zhang XY, Liu ZX, Zhang YF, Xu LX, Chen MK, Zhou YF, Yu J, Li XX, Zhang N
Cell & bioscience 2023 Mar 22;13(1):63
Cell & bioscience 2023 Mar 22;13(1):63
CCR7 Mediates Cell Invasion and Migration in Extrahepatic Cholangiocarcinoma by Inducing Epithelial-Mesenchymal Transition.
Oba M, Nakanishi Y, Mitsuhashi T, Sasaki K, Hatanaka KC, Sasaki M, Nange A, Okumura A, Hayashi M, Yoshida Y, Nitta T, Ueno T, Yamada T, Ono M, Kuwabara S, Okamura K, Tsuchikawa T, Nakamura T, Noji T, Asano T, Tanaka K, Takayama K, Hatanaka Y, Hirano S
Cancers 2023 Mar 21;15(6)
Cancers 2023 Mar 21;15(6)
LncRNA-MIAT activates hepatic stellate cells via regulating Hippo pathway and epithelial-to-mesenchymal transition.
Zhan Y, Tao Q, Meng Q, Zhang R, Lin L, Li X, Zheng L, Zheng J
Communications biology 2023 Mar 18;6(1):285
Communications biology 2023 Mar 18;6(1):285
EGR1 induces EMT in pancreatic cancer via a P300/SNAI2 pathway.
Wang Y, Qin C, Zhao B, Li Z, Li T, Yang X, Zhao Y, Wang W
Journal of translational medicine 2023 Mar 17;21(1):201
Journal of translational medicine 2023 Mar 17;21(1):201
PRAME Promotes Cervical Cancer Proliferation and Migration via Wnt/β-Catenin Pathway Regulation.
Chen X, Jiang M, Zhou S, Chen H, Song G, Wu Y, Zhu X
Cancers 2023 Mar 16;15(6)
Cancers 2023 Mar 16;15(6)
F-box and leucine-rich repeat 6 promotes gastric cancer progression via the promotion of epithelial-mesenchymal transition.
Meng L, Hu YT, Xu AM
World journal of gastrointestinal oncology 2023 Mar 15;15(3):490-503
World journal of gastrointestinal oncology 2023 Mar 15;15(3):490-503
Ultrasound-mediated mesoporous silica nanoparticles loaded with PDLIM5 siRNA inhibit gefitinib resistance in NSCLC cells by attenuating EMT.
Wu H, Lv WH, Zhu YY, Jia YY, Nie F
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2023 Mar 1;182:106372
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2023 Mar 1;182:106372
TMEM2 induces epithelial-mesenchymal transition and promotes resistance to temozolomide in GBM cells.
Gao L, Tong S, Liu J, Cai J, Ye Z, Zhou L, Song P, Li Z, Lei P, Wei H, Hua Q, Tian D, Cai Q
Heliyon 2023 Jun;9(6):e16559
Heliyon 2023 Jun;9(6):e16559
Potent carotenoid astaxanthin expands the anti-cancer activity of cisplatin in human prostate cancer cells.
Erzurumlu Y, Catakli D, Dogan HK
Journal of natural medicines 2023 Jun;77(3):572-583
Journal of natural medicines 2023 Jun;77(3):572-583
PDK1 regulates the progression of esophageal squamous cell carcinoma through metabolic reprogramming.
Ma Y, Zhang X, Han X, Hao Z, Ji R, Li J, Guo W, Zhang Y, Guan F, Ma S
Molecular carcinogenesis 2023 Jun;62(6):866-881
Molecular carcinogenesis 2023 Jun;62(6):866-881
Rabeprazole destroyed gastric epithelial barrier function through FOXF1/STAT3-mediated ZO-1 expression.
Yang F, Li L, Zhou Y, Pan W, Liang X, Huang L, Huang J, Cheng Y, Geng L, Xu W, Gong S
Clinical and experimental pharmacology & physiology 2023 Jun;50(6):516-526
Clinical and experimental pharmacology & physiology 2023 Jun;50(6):516-526
FAM83A promotes the progression and metastasis of human pancreatic neuroendocrine tumors by inducing the epithelial-mesenchymal transition via the PI3K/AKT and ERK pathways.
Zhou B, Zhou X, Zhan C, Jin M, Yan S
Journal of endocrinological investigation 2023 Jun;46(6):1115-1130
Journal of endocrinological investigation 2023 Jun;46(6):1115-1130
ZNF133 is a potent suppressor in breast carcinogenesis through dampening L1CAM, a driver for tumor progression.
Li L, Wang X, Hu K, Liu X, Qiu L, Bai C, Cui Y, Wang B, Wang Z, Wang H, Cheng R, Hua J, Hai L, Wang M, Liu M, Song Z, Xiao C, Li B
Oncogene 2023 Jun;42(27):2166-2182
Oncogene 2023 Jun;42(27):2166-2182
Circ_0079530 stimulates THBS2 to promote the malignant progression of non-small cell lung cancer by sponging miR-584-5p.
Fang K, Deng Y, Yang P, Zhang Y, Luo D, Wang F, Cai Z, Liu Y
Histology and histopathology 2023 Jun;38(6):681-693
Histology and histopathology 2023 Jun;38(6):681-693
Meso-Hannokinol inhibits breast cancer bone metastasis via the ROS/JNK/ZEB1 axis.
Zhu Y, Yin WF, Yu P, Zhang C, Sun MH, Kong LY, Yang L
Phytotherapy research : PTR 2023 Jun;37(6):2262-2279
Phytotherapy research : PTR 2023 Jun;37(6):2262-2279
Loss of exosomal miR-200b-3p from hypoxia cancer-associated fibroblasts promotes tumorigenesis and reduces sensitivity to 5-Flourouracil in colorectal cancer via upregulation of ZEB1 and E2F3.
Gong W, Guo Y, Yuan H, Chai R, Wan Z, Zheng B, Hu X, Chen B, Gao S, Dai Q, Yu P, Tu S
Cancer gene therapy 2023 Jun;30(6):905-916
Cancer gene therapy 2023 Jun;30(6):905-916
HnRNPAB is an independent prognostic factor in non‑small cell lung cancer and is involved in cell proliferation and metastasis.
Wang Q, Gou X, Liu L, Zhang T, Yuan H, Zhao Y, Xie Y, Zhou J, Song K
Oncology letters 2023 Jun;25(6):215
Oncology letters 2023 Jun;25(6):215
Silencing of FAM111B inhibits tumor growth and promotes apoptosis by decreasing AKT activity in ovarian cancer.
Wang W, Gu Y, Ni H, Quan Q, Guo L
Experimental biology and medicine (Maywood, N.J.) 2023 Jun;248(12):1043-1055
Experimental biology and medicine (Maywood, N.J.) 2023 Jun;248(12):1043-1055
Intracellular hydrogelation of macrophage conjugated probiotics for hitchhiking delivery and combined treatment of colitis.
Wang J, Hu D, Chen Q, Liu T, Zhou X, Xu Y, Zhou H, Gu D, Gao C
Materials today. Bio 2023 Jun;20:100679
Materials today. Bio 2023 Jun;20:100679
Rosmarinic Acid-Crosslinked Supramolecular Nanoassembly with Self-Regulated Photodynamic and Anti-Metastasis Properties for Synergistic Photoimmunotherapy.
Zhou Y, Zhang Y, Jiang C, Chen Y, Tong F, Yang X, Wang Y, Xia X, Gao H
Small (Weinheim an der Bergstrasse, Germany) 2023 Jun;19(23):e2300594
Small (Weinheim an der Bergstrasse, Germany) 2023 Jun;19(23):e2300594
LINC01116 modulates EMT process via binding with AGO1 mRNA in oesophageal squamous cell carcinoma.
Fang X, Ren LH, Shrestha SM, Ji Q, Xu Z, Wang D, Ding Q, Liang X, Shi RH
Biochimica et biophysica acta. Molecular cell research 2023 Jun;1870(5):119447
Biochimica et biophysica acta. Molecular cell research 2023 Jun;1870(5):119447
Squalene epoxidase promotes hepatocellular carcinoma development by activating STRAP transcription and TGF-β/SMAD signalling.
Zhang Z, Wu W, Jiao H, Chen Y, Ji X, Cao J, Yin F, Yin W
British journal of pharmacology 2023 Jun;180(12):1562-1581
British journal of pharmacology 2023 Jun;180(12):1562-1581
TRIM55 inhibits colorectal cancer development via enhancing protein degradation of c-Myc.
Lin M, Fang Z, Lin X, Zhou W, Wang Y, Han S, Ye M, Zhu F
Cancer medicine 2023 Jun;12(12):13511-13521
Cancer medicine 2023 Jun;12(12):13511-13521
Cancer cell-derived CD69 induced under lipid and oxygen starvation promotes ovarian cancer progression through fibronectin.
Koizume S, Kanayama T, Kimura Y, Hirano H, Takahashi T, Ota Y, Miyazaki K, Yoshihara M, Nakamura Y, Yokose T, Kato H, Takenaka K, Sato S, Tadokoro H, Miyagi E, Miyagi Y
Cancer science 2023 Jun;114(6):2485-2498
Cancer science 2023 Jun;114(6):2485-2498
MED27 plays a tumor-promoting role in breast cancer progression by targeting KLF4.
Wang R, Yu W, Zhu T, Lin F, Hua C, Ru L, Guo P, Wan X, Xue G, Guo Z, Han S, Lv K, Zhang G, Ge H, Guo W, Xu L, Deng W
Cancer science 2023 Jun;114(6):2277-2292
Cancer science 2023 Jun;114(6):2277-2292
Effect of STK3 on proliferation and apoptosis of pancreatic cancer cells via PI3K/AKT/mTOR pathway.
Chen J, Liu F, Wu J, Yang Y, He J, Wu F, Yang K, Li J, Jiang Z, Jiang Z
Cellular signalling 2023 Jun;106:110642
Cellular signalling 2023 Jun;106:110642
Clinicopathological features and immunophenotype of Silva pattern system in endocervical adenocarcinoma.
Zeng C, Wu JK, Lu X
International journal of experimental pathology 2023 Jun;104(3):140-150
International journal of experimental pathology 2023 Jun;104(3):140-150
MTAP-ANRIL gene fusion promotes melanoma epithelial-mesenchymal transition-like process by activating the JNK and p38 signaling pathways.
Lin Z, Lei Y, Wen M, He Q, Tian D, Xie H
Scientific reports 2023 Jun 5;13(1):9073
Scientific reports 2023 Jun 5;13(1):9073
Silencing of AJAP1 expression by promoter methylation activates the Wnt/β-catenin signaling pathway to promote tumor proliferation and metastasis in salivary adenoid cystic carcinoma.
Jiang L, Liu Y, Pan Y, Tan Z, Wang J, Zheng G, Qian C, Xu S, Zhu X, Ma W, Guerrini S, Infante-Cossio P, Wu J, Ge M, Cai X
Gland surgery 2023 Jun 30;12(6):834-852
Gland surgery 2023 Jun 30;12(6):834-852
Morusin shows potent antitumor activity for melanoma through apoptosis induction and proliferation inhibition.
Liu W, Ji Y, Wang F, Li C, Shi S, Liu R, Li Q, Guo L, Liu Y, Cui H
BMC cancer 2023 Jun 29;23(1):602
BMC cancer 2023 Jun 29;23(1):602
GATA zinc finger protein p66β promotes breast cancer cell migration by acting as a co-activator of Snail.
Zou X, Ma L, Zhang Y, Zhang Q, Xu C, Zhang D, Chu Y, Zhang J, Li M, Zhang H, Wang J, Peng C, Wei G, Wu Y, Hou Z, Jia H
Cell death & disease 2023 Jun 28;14(6):382
Cell death & disease 2023 Jun 28;14(6):382
High glucose promotes the progression of colorectal cancer by activating the BMP4 signaling and inhibited by glucagon-like peptide-1 receptor agonist.
Ma B, Wang X, Ren H, Li Y, Zhang H, Yang M, Li J
BMC cancer 2023 Jun 27;23(1):594
BMC cancer 2023 Jun 27;23(1):594
TRIM29 hypermethylation drives esophageal cancer progression via suppression of ZNF750.
Yi Q, Zhao Y, Xia R, Wei Q, Chao F, Zhang R, Bian P, Lv L
Cell death discovery 2023 Jun 26;9(1):191
Cell death discovery 2023 Jun 26;9(1):191
PLAGL2 promotes Snail expression and gastric cancer progression via UCA1/miR-145-5p/YTHDF1 axis.
Chen W, He Q, Liu J, Li N, Xiao K, Chen H
Carcinogenesis 2023 Jun 24;44(4):328-340
Carcinogenesis 2023 Jun 24;44(4):328-340
SIAH1/CTR9 axis promotes the epithelial-mesenchymal transition of hepatocellular carcinoma.
Liu Z, Luo P, Cao K, Hu Q, Hu B, Cui L, Wang X, Shi H, Zhang B, Wang R
Carcinogenesis 2023 Jun 24;44(4):304-316
Carcinogenesis 2023 Jun 24;44(4):304-316
FBXO28 promotes proliferation, invasion, and metastasis of pancreatic cancer cells through regulation of SMARCC2 ubiquitination.
Liu S, Liu P, Zhu C, Yang R, He Z, Li Y, Li Y, Fei X, Hou J, Wang X, Pan Y
Aging 2023 Jun 21;15(12):5381-5398
Aging 2023 Jun 21;15(12):5381-5398
UBAP2 plays a role in bone homeostasis through the regulation of osteoblastogenesis and osteoclastogenesis.
Kim J, Kim BY, Lee JS, Jeong YM, Cho HJ, Park E, Kim D, Kim SS, Kim BT, Choi YJ, Won YY, Jin HS, Chung YS, Jeong SY
Nature communications 2023 Jun 20;14(1):3668
Nature communications 2023 Jun 20;14(1):3668
Regulon analysis identifies protective FXR and CREB5 in proximal tubules in early diabetic kidney disease.
Shi W, Le W, Tang Q, Shi S, Shi J
BMC nephrology 2023 Jun 19;24(1):180
BMC nephrology 2023 Jun 19;24(1):180
An In Vivo CRISPR Screen Identifies That SNRPC Promotes Triple-Negative Breast Cancer Progression.
Lu XX, Yang WX, Pei YC, Luo H, Li XG, Wang YJ, Zhang GL, Ling H, Shao ZM, Hu X
Cancer research 2023 Jun 15;83(12):2000-2015
Cancer research 2023 Jun 15;83(12):2000-2015
ORP8 inhibits renal cell carcinoma progression by accelerating Stathmin1 degradation and microtubule polymerization.
Zhang L, Pan Q, Wu Y, Zhang P, Li S, Xu Y, Li D, Zheng M, Pei D, Wang Q
Experimental cell research 2023 Jun 1;427(1):113601
Experimental cell research 2023 Jun 1;427(1):113601
Targeting the mitochondrial calcium uniporter inhibits cancer progression and alleviates cisplatin resistance in esophageal squamous cell carcinoma.
Miao Y, Wang X, Lai Y, Huang Y, Yin H, Meng X, Liu H, Hou R, Lin W, Zhang X, Zhang X, Chai BC, Zhang F, Guo L, Yang S
International journal of oncology 2023 Jul;63(1)
International journal of oncology 2023 Jul;63(1)
ASPM promotes migration and invasion of anaplastic thyroid carcinoma by stabilizing KIF11.
Fang Q, Li Q, Qi Y, Pan Z, Feng T, Xin W
Cell biology international 2023 Jul;47(7):1209-1221
Cell biology international 2023 Jul;47(7):1209-1221
ORP5 promotes migration and invasion of cervical cancer cells by inhibiting endoplasmic reticulum stress.
Wu Y, Min L, Zhang P, Zhang L, Xu Y, Li D, Zheng M, Pei D, Wang Q
Cell stress & chaperones 2023 Jul;28(4):395-407
Cell stress & chaperones 2023 Jul;28(4):395-407
MRPL51 is a downstream target of FOXM1 in promoting the malignant behaviors of lung adenocarcinoma.
Zhang W, Yu L, Xu C, Tang T, Cao J, Chen L, Pang X, Ren W
Oncology letters 2023 Jul;26(1):298
Oncology letters 2023 Jul;26(1):298
Analysis and validation of the potential of the MYO1E gene in pancreatic adenocarcinoma based on a bioinformatics approach.
Liu S, Liu P, Fei X, Zhu C, Hou J, Wang X, Pan Y
Oncology letters 2023 Jul;26(1):285
Oncology letters 2023 Jul;26(1):285
Dach1 deficiency drives alveolar epithelium apoptosis in pulmonary fibrosis via modulating C-Jun/Bim activity.
Lu Y, Tang K, Wang S, Tian Z, Fan Y, Li B, Wang M, Zhao J, Xie J
Translational research : the journal of laboratory and clinical medicine 2023 Jul;257:54-65
Translational research : the journal of laboratory and clinical medicine 2023 Jul;257:54-65
TANGO1 interacts with NRTN to promote hepatocellular carcinoma progression by regulating the PI3K/AKT/mTOR signaling pathway.
Man J, Zhou W, Zuo S, Zhao X, Wang Q, Ma H, Li HY
Biochemical pharmacology 2023 Jul;213:115615
Biochemical pharmacology 2023 Jul;213:115615
SIRT3-mediated autophagy contributes to ferroptosis-induced anticancer by inducing the formation of BECN1-SLC7A11 complex.
Huang P, Zhao H, Pan X, Li J, Pan W, Dai H, Wang J, Xia C, Liu F
Biochemical pharmacology 2023 Jul;213:115592
Biochemical pharmacology 2023 Jul;213:115592
The role of DYNLT3 in breast cancer proliferation, migration, and invasion via epithelial-to-mesenchymal transition.
Wang H, Chen X, Jin Y, Liu T, Song Y, Zhu X, Zhu X
Cancer medicine 2023 Jul;12(14):15289-15303
Cancer medicine 2023 Jul;12(14):15289-15303
Pan-cancer analysis of oncogenic role of insulin-like growth factor-binding proteins and validation in ovarian cancer.
Tan W, Zhang J, Deng Z, Dai F, Tang L, Hu W, Liu H
Cancer medicine 2023 Jul;12(13):14833-14850
Cancer medicine 2023 Jul;12(13):14833-14850
HERPUD1, a Member of the Endoplasmic Reticulum Protein Quality Control Mechanism, may be a Good Target for Suppressing Tumorigenesis in Breast Cancer Cells.
Erzurumlu Y, Doğanlar Y, Doğan HK, Çataklı D
Turkish journal of pharmaceutical sciences 2023 Jul 7;20(3):157-164
Turkish journal of pharmaceutical sciences 2023 Jul 7;20(3):157-164
LncRNA LZTS1-AS1 induces proliferation, metastasis and inhibits autophagy of pancreatic cancer cells through the miR-532 /TWIST1 signaling pathway.
Wu H, Li A, Zheng Q, Gu J, Zhou W
Cancer cell international 2023 Jul 4;23(1):130
Cancer cell international 2023 Jul 4;23(1):130
The promoting effect and mechanism of Nrf2 on cell metastasis in cervical cancer.
Zhang M, Hong X, Ma N, Wei Z, Ci X, Zhang S
Journal of translational medicine 2023 Jul 4;21(1):433
Journal of translational medicine 2023 Jul 4;21(1):433
Modified Podophyllotoxin Phenoxyacetamide Phenylacetate Derivatives: Tubulin/AKT1 Dual-Targeting and Potential Anticancer Agents for Human NSCLC.
Lin H, Ai D, Liu Q, Wang X, Gao J, Chen Q, Ruan L, Tao Y, Gao J, Wang L
Journal of natural products 2023 Jul 28;86(7):1844-1854
Journal of natural products 2023 Jul 28;86(7):1844-1854
Lnc-LRRTM4 promotes proliferation, metastasis and EMT of colorectal cancer through activating LRRTM4 transcription.
Zhang J, Meng X, Zhou Y, Jiang Z, Chen H, Meng Z, Zhang Q, Chen W
Cancer cell international 2023 Jul 19;23(1):142
Cancer cell international 2023 Jul 19;23(1):142
NCOA7 Regulates Growth and Metastasis of Clear Cell Renal Cell Carcinoma via MAPK/ERK Signaling Pathway.
Guo J, Ke S, Chen Q, Zhou J, Guo J, Qiu T
International journal of molecular sciences 2023 Jul 18;24(14)
International journal of molecular sciences 2023 Jul 18;24(14)
PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling.
Chen H, Yang W, Li Y, Ji Z
Cell death & disease 2023 Jul 15;14(7):433
Cell death & disease 2023 Jul 15;14(7):433
Long noncoding RNA LINC01594 inhibits the CELF6-mediated splicing of oncogenic CD44 variants to promote colorectal cancer metastasis.
Liu B, Song A, Gui P, Wang J, Pan Y, Li C, Li S, Zhang Y, Jiang T, Xu Y, Pei D, Song J
Cell death & disease 2023 Jul 14;14(7):427
Cell death & disease 2023 Jul 14;14(7):427
AFP deletion leads to anti-tumorigenic but pro-metastatic roles in liver cancers with concomitant CTNNB1 mutations.
Xu Y, Zhang X, Zhang R, Sun Y, Liu J, Luo C, Yang J, Fang W, Guo Q, Wei L
Cancer letters 2023 Jul 10;566:216240
Cancer letters 2023 Jul 10;566:216240
Knockdown of ABCB7 inhibits esophageal cancer progression by inhibiting the TGF-β/Smad signaling.
Feng S, Jia J, Lv G, Wang Y
Archives of biochemistry and biophysics 2023 Jul 1;742:109620
Archives of biochemistry and biophysics 2023 Jul 1;742:109620
TATA-box-binding protein promotes hepatocellular carcinoma metastasis through epithelial-mesenchymal transition.
Cao J, Yang S, Luo T, Yang R, Zhu H, Zhao T, Jiang K, Xu B, Wang Y, Chen F
Hepatology communications 2023 Jul 1;7(7)
Hepatology communications 2023 Jul 1;7(7)
Extracellular Vesicles from Carcinoma-associated Fibroblasts Promote EMT of Salivary Adenoid Cystic Carcinoma Via IL-6.
Al-Raimi HAI, Kong J, Ran Y, Zhu L, Li J, Liu X, Yang X, Qi D, Liu T
Archives of medical research 2023 Jan;54(1):27-36
Archives of medical research 2023 Jan;54(1):27-36
Biochemical and clinical effects of RPS20 expression in renal clear cell carcinoma.
Shen C, Chen Z, Zhang Y, Xu W, Peng R, Jiang J, Zuo W, Fan Y, Zheng B
Oncology reports 2023 Jan;49(1)
Oncology reports 2023 Jan;49(1)
SPARC expression in tumor microenvironment induces partial epithelial-to-mesenchymal transition of esophageal adenocarcinoma cells via cooperating with TGF-β signaling.
Ma W, Yan Y, Bai S, Zhou Y, Wang X, Feng Z, Li G, Zhou S, Zhang J, Ren J
Cell biology international 2023 Jan;47(1):250-259
Cell biology international 2023 Jan;47(1):250-259
Exosome-transmitted circIFNGR2 Modulates Ovarian Cancer Metastasis via miR-378/ST5 Axis.
Chen X, Ren X, E J, Zhou Y, Bian R
Molecular and cellular biology 2023 Jan;43(1):22-42
Molecular and cellular biology 2023 Jan;43(1):22-42
Resveratrol reverses TGF-β1-mediated invasion and metastasis of breast cancer cells via the SIRT3/AMPK/autophagy signal axis.
Wang J, Huang P, Pan X, Xia C, Zhang H, Zhao H, Yuan Z, Liu J, Meng C, Liu F
Phytotherapy research : PTR 2023 Jan;37(1):211-230
Phytotherapy research : PTR 2023 Jan;37(1):211-230
Quercetin inhibits the amphiregulin/EGFR signaling-mediated renal tubular epithelial-mesenchymal transition and renal fibrosis in obstructive nephropathy.
Wang Q, Wang F, Li X, Ma Z, Jiang D
Phytotherapy research : PTR 2023 Jan;37(1):111-123
Phytotherapy research : PTR 2023 Jan;37(1):111-123
Effect of transmembrane protein 100 on prostate cancer progression by regulating SCNN1D through the FAK/PI3K/AKT pathway.
Ye Z, Xia Y, Li L, Li B, Chen W, Han S, Zhou X, Chen L, Yu W, Ruan Y, Cheng F
Translational oncology 2023 Jan;27:101578
Translational oncology 2023 Jan;27:101578
CD166-specific CAR-T cells potently target colorectal cancer cells.
He S, Li S, Guo J, Zeng X, Liang D, Zhu Y, Li Y, Yang D, Zhao X
Translational oncology 2023 Jan;27:101575
Translational oncology 2023 Jan;27:101575
Circ_0004491 stimulates guanine nucleotide-binding protein alpha subunit to inhibit the malignant progression of oral squamous cell carcinoma by sponging miR-2278.
Cheng T, Huang F, Zhang Y, Zhou Z
Journal of dental sciences 2023 Jan;18(1):237-247
Journal of dental sciences 2023 Jan;18(1):237-247
Exosomal miR-543 derived from umbilical cord mesenchymal stem cells ameliorates endometrial fibrosis in intrauterine adhesion via downregulating N-cadherin.
Yuan D, Guo T, Qian H, Jin C, Ge H, Zhao Y, Zhu D, Lin M, Wang H, Yu H
Placenta 2023 Jan;131:75-81
Placenta 2023 Jan;131:75-81
CDCA7 promotes TGF-β-induced epithelial-mesenchymal transition via transcriptionally regulating Smad4/Smad7 in ESCC.
Li H, Wang S, Li X, Weng Y, Guo D, Kong P, Cheng C, Wang Y, Zhang L, Cheng X, Cui Y
Cancer science 2023 Jan;114(1):91-104
Cancer science 2023 Jan;114(1):91-104
Multiomics analyses and machine learning of nuclear receptor coactivator 6 reveal its essential role in hepatocellular carcinoma.
Fang Y, Xu Y, Liao W, Ji T, Yu L, Li L, Pan M, Yang D
Cancer science 2023 Jan;114(1):75-90
Cancer science 2023 Jan;114(1):75-90
Mouse-human species differences in early testicular development and its implications.
Cunha GR, Cao M, Aksel S, Derpinghaus A, Baskin LS
Differentiation; research in biological diversity 2023 Jan-Feb;129:79-95
Differentiation; research in biological diversity 2023 Jan-Feb;129:79-95
Cancer susceptibility 18 positively regulates NUAK Family Kinase 1 expression to promote migration and invasion via sponging of miR-5586-5p in cervical cancer cells.
Wang J, Zhang B, Gong S, Liu Y, Yi L, Long Y
International journal of immunopathology and pharmacology 2023 Jan-Dec;37:3946320231223310
International journal of immunopathology and pharmacology 2023 Jan-Dec;37:3946320231223310
Hypermethylation-Mediated lncRNA MAGI2-AS3 Downregulation Facilitates Malignant Progression of Laryngeal Squamous Cell Carcinoma via Interacting With SPT6.
Wang J, Yang C, Cao H, Yang J, Meng W, Yu M, Yu L, Wang B
Cell transplantation 2023 Jan-Dec;32:9636897231154574
Cell transplantation 2023 Jan-Dec;32:9636897231154574
GOLM1 Promotes Epithelial-Mesenchymal Transition by Activating TGFβ1/Smad2 Signaling in Prostate Cancer.
Qin X, Liu L, Li Y, Luo H, Chen H, Weng X
Technology in cancer research & treatment 2023 Jan-Dec;22:15330338231153618
Technology in cancer research & treatment 2023 Jan-Dec;22:15330338231153618
Cryptotanshinone modulates proliferation, apoptosis, and fibrosis through inhibiting AR and EGFR/STAT3 axis to ameliorate benign prostatic hyperplasia progression.
Wei P, Lin D, Zhang M, Luo C, Wu X, Deng B, Cui K, Chen Z
European journal of pharmacology 2023 Jan 5;938:175434
European journal of pharmacology 2023 Jan 5;938:175434
Circular hsa_circ_0020377 regulates KLF7 by targeting miR-194-5p to facilitate tumor cell malignant behaviors and glycolysis in oral squamous cell carcinoma progression.
Hei N, Liu P, Jin L, Peng S, Bao Y
Functional & integrative genomics 2023 Jan 31;23(1):52
Functional & integrative genomics 2023 Jan 31;23(1):52
Alginate Oligosaccharides Prevent Dextran-Sulfate-Sodium-Induced Ulcerative Colitis via Enhancing Intestinal Barrier Function and Modulating Gut Microbiota.
Wu A, Gao Y, Kan R, Ren P, Xue C, Kong B, Tang Q
Foods (Basel, Switzerland) 2023 Jan 3;12(1)
Foods (Basel, Switzerland) 2023 Jan 3;12(1)
Glycolysis-Related Gene Analyses Indicate That DEPDC1 Promotes the Malignant Progression of Oral Squamous Cell Carcinoma via the WNT/β-Catenin Signaling Pathway.
Huang G, Chen S, Washio J, Paka Lubamba G, Takahashi N, Li C
International journal of molecular sciences 2023 Jan 19;24(3)
International journal of molecular sciences 2023 Jan 19;24(3)
CCL21/CCR7 Axis Contributes to Trophoblastic Cell Migration and Invasion in Preeclampsia by Affecting the Epithelial Mesenchymal Transition via the ERK1/2 Signaling Pathway.
Liu Z, He J, Jin P, Ran Y, Yin N, Qi H
Biology 2023 Jan 18;12(2)
Biology 2023 Jan 18;12(2)
Hypoxia-induced ROS aggravate tumor progression through HIF-1α-SERPINE1 signaling in glioblastoma.
Zhang L, Cao Y, Guo X, Wang X, Han X, Kanwore K, Hong X, Zhou H, Gao D
Journal of Zhejiang University. Science. B 2023 Jan 15;24(1):32-49
Journal of Zhejiang University. Science. B 2023 Jan 15;24(1):32-49
Molecular mechanism of the miR-7/BCL2L1/P53 signaling axis regulating the progression of hepatocellular carcinoma.
Zhang N, Wang F, Zhu L, Chang R, Mok SRS, Peixoto RD, Tang W, Chen Z
Annals of translational medicine 2023 Jan 15;11(1):12
Annals of translational medicine 2023 Jan 15;11(1):12
SF3B4 promotes Twist1 expression and clear cell renal cell carcinoma progression by facilitating the export of KLF 16 mRNA from the nucleus to the cytoplasm.
Yang Z, Wang YX, Wen JK, Gao HT, Han ZW, Qi JC, Gu JF, Zhao CM, Zhang H, Shi B, Wang DD, Wang XL, Qu CB
Cell death & disease 2023 Jan 13;14(1):26
Cell death & disease 2023 Jan 13;14(1):26
FRMD3 inhibits the growth and metastasis of breast cancer through the ubiquitination-mediated degradation of vimentin and subsequent impairment of focal adhesion.
Shao W, Li J, Piao Q, Yao X, Li M, Wang S, Song Z, Sun Y, Zheng L, Wang G, Liu L, Yu C, Huang Y, Bao Y, Sun L
Cell death & disease 2023 Jan 11;14(1):13
Cell death & disease 2023 Jan 11;14(1):13
CMTM6 overexpression confers trastuzumab resistance in HER2-positive breast cancer.
Xing F, Gao H, Chen G, Sun L, Sun J, Qiao X, Xue J, Liu C
Molecular cancer 2023 Jan 10;22(1):6
Molecular cancer 2023 Jan 10;22(1):6
Crosstalk between 5-methylcytosine and N(6)-methyladenosine machinery defines disease progression, therapeutic response and pharmacogenomic landscape in hepatocellular carcinoma.
Tian Y, Xiao H, Yang Y, Zhang P, Yuan J, Zhang W, Chen L, Fan Y, Zhang J, Cheng H, Deng T, Yang L, Wang W, Chen G, Wang P, Gong P, Niu X, Zhang X
Molecular cancer 2023 Jan 10;22(1):5
Molecular cancer 2023 Jan 10;22(1):5
High expression of NLRP12 predicts poor prognosis in patients with intracranial glioma.
Cheng YW, Chen YY, Lin CJ, Chen YT, Lieu AS, Tsai HP, Kwan AL
Journal of the Chinese Medical Association : JCMA 2023 Jan 1;86(1):88-97
Journal of the Chinese Medical Association : JCMA 2023 Jan 1;86(1):88-97
Etomidate elicits anti-tumor capacity by disrupting the JAK2/STAT3 signaling pathway in hepatocellular carcinoma.
Xu J, Zhang L, Li N, Dai J, Zhang R, Yao F, Zhou S, Wu Z, Zhou H, Zhou L, Li Q, Wang X, Liu C
Cancer letters 2023 Jan 1;552:215970
Cancer letters 2023 Jan 1;552:215970
GOLM1 facilitates human colorectal cancer progression and metastasis via activating the AKT/GSK3β/EMT axis.
Mao Z, Wu Y, Yao P, Xing C
Neoplasma 2023 Feb;70(1):136-144
Neoplasma 2023 Feb;70(1):136-144
The TGF-β/Smad(2/3) signaling pathway is involved in Musashi2-induced invasion and metastasis of colorectal cancer.
Yu ZL, Liu J, Ning ZK, Tian HK, Wu X, Huang YF, Wu ZC, Zong Z, Zhou TC
Molecular carcinogenesis 2023 Feb;62(2):261-276
Molecular carcinogenesis 2023 Feb;62(2):261-276
Silencing CircEIF3I/miR-526b-5p Axis Epigenetically Targets HGF/c-Met Signal to Hinder the Malignant Growth, Metastasis and Angiogenesis of Hepatocellular Carcinoma.
Liu Y, Xiao X, Wang J, Wang Y, Yu Y
Biochemical genetics 2023 Feb;61(1):48-68
Biochemical genetics 2023 Feb;61(1):48-68
The long non-coding RNA PANDAR regulates cell proliferation and epithelial-to-mesenchymal transition in glioma.
Guo J, Xiao D, Lin Z, Sui C
Histology and histopathology 2023 Feb;38(2):199-208
Histology and histopathology 2023 Feb;38(2):199-208
Novel long noncoding RNA LINC02820 augments TNF signaling pathway to remodel cytoskeleton and potentiate metastasis in esophageal squamous cell carcinoma.
Wang J, Huang TJ, Mei Y, Luo FF, Xie DH, Peng LX, Liu BQ, Fan ML, Zhang JB, Zheng ST, Qian CN, Huang BJ
Cancer gene therapy 2023 Feb;30(2):375-387
Cancer gene therapy 2023 Feb;30(2):375-387
Role of SUMOylation of STAT1 in tubular epithelial‑mesenchymal transition induced by high glucose.
Gu C, Gao F, Zhang S, Kang L, Zhang W, Feng X, Liu J, Tian Y, Wei Q, Du Y, Xing Y, Liu Q, Liu S
Molecular medicine reports 2023 Feb;27(2)
Molecular medicine reports 2023 Feb;27(2)
Palladin promotes cancer stem cell-like properties in lung cancer by activating Wnt/Β-Catenin signaling.
Shu X, Chen M, Liu SY, Yu L, Sun LX, Sun LC, Ran YL
Cancer medicine 2023 Feb;12(4):4510-4520
Cancer medicine 2023 Feb;12(4):4510-4520
Hepatic stellate cell-released CXCL1 aggravates HCC malignant behaviors through the MIR4435-2HG/miR-506-3p/TGFB1 axis.
Li S, Hu X, Yu S, Yi P, Chen R, Huang Z, Huang Y, Huang Y, Zhou R, Fan X
Cancer science 2023 Feb;114(2):504-520
Cancer science 2023 Feb;114(2):504-520
Ferroptosis is involved in corpus cavernosum smooth muscle cells impairment in diabetes mellitus-induced erectile dysfunction.
Xu W, Sun T, Wang J, Wang T, Wang S, Liu J, Liu K, Li H
Andrology 2023 Feb;11(2):332-343
Andrology 2023 Feb;11(2):332-343
LIM and Cysteine-Rich Domains 1 Promotes Transforming Growth Factor β1-Induced Epithelial-Mesenchymal Transition in Human Kidney 2 Cells.
Yu R, Wu Y, He P, Bai Y, Zhang Y, Bian X, Sun G, Zhang B
Laboratory investigation; a journal of technical methods and pathology 2023 Feb;103(2):100016
Laboratory investigation; a journal of technical methods and pathology 2023 Feb;103(2):100016
TRIM40 is a pathogenic driver of inflammatory bowel disease subverting intestinal barrier integrity.
Kang S, Kim J, Park A, Koh M, Shin W, Park G, Lee TA, Kim HJ, Han H, Kim Y, Choi MK, Park JH, Lee E, Cho HS, Park HW, Cheon JH, Lee S, Park B
Nature communications 2023 Feb 9;14(1):700
Nature communications 2023 Feb 9;14(1):700
Ginsenoside Rg3 Ameliorates DSS-Induced Colitis by Inhibiting NLRP3 Inflammasome Activation and Regulating Microbial Homeostasis.
Liu D, Tian Q, Liu K, Ren F, Liu G, Zhou J, Yuan L, Fang Z, Zou B, Wang S
Journal of agricultural and food chemistry 2023 Feb 8;
Journal of agricultural and food chemistry 2023 Feb 8;
RRP15 deficiency induces ribosome stress to inhibit colorectal cancer proliferation and metastasis via LZTS2-mediated β-catenin suppression.
Dong Z, Li J, Dai W, Yu D, Zhao Y, Liu S, Li X, Zhang Z, Zhang R, Liang X, Kong Q, Jin S, Jiang H, Jiang W, Ding C
Cell death & disease 2023 Feb 7;14(2):89
Cell death & disease 2023 Feb 7;14(2):89
Proto-Oncogene FAM50A Can Regulate the Immune Microenvironment and Development of Hepatocellular Carcinoma In Vitro and In Vivo.
Xie X, Li L, Tao S, Chen M, Fei L, Yang Q, Huang C, Chen L
International journal of molecular sciences 2023 Feb 6;24(4)
International journal of molecular sciences 2023 Feb 6;24(4)
The UDPase ENTPD5 regulates ER stress-associated renal injury by mediating protein N-glycosylation.
Xu L, Zhou Y, Wang G, Bo L, Jin B, Dai L, Lu Q, Cai X, Hu L, Liu L, Wu Y, Chang X, Huang Y, Song L, Zhang T, Wang Y, Xiao Y, Zhang F, Liu L, Shi M, Wang T, Guo B
Cell death & disease 2023 Feb 27;14(2):166
Cell death & disease 2023 Feb 27;14(2):166
Serum Response Factor-Regulated IDO1/Kyn-Ahr Pathway Promotes Tumorigenesis of Oral Squamous Cell Carcinoma.
Xu M, Zhu F, Yin Q, Yin H, Fang S, Luo G, Huang J, Huang W, Liu F, Zhong M, Deng X
Cancers 2023 Feb 19;15(4)
Cancers 2023 Feb 19;15(4)
Aerobic exercise inhibits renal EMT by promoting irisin expression in SHR.
Luo M, Luo S, Xue Y, Chang Q, Yang H, Dong W, Zhang T, Cao S
iScience 2023 Feb 17;26(2):105990
iScience 2023 Feb 17;26(2):105990
The malignancy of chordomas is enhanced via a circTLK1/miR-16-5p/Smad3 positive feedback axis.
Lou J, Zhang H, Huang Q, Chen C, Wang W, Niu J, Xu J, Ren T, Huang Y, Tang X, Guo W
Cell death discovery 2023 Feb 15;9(1):64
Cell death discovery 2023 Feb 15;9(1):64
ELAC2 Functions as a Key Gene in the Early Development of Placental Formation Based on WGCNA.
Liang J, Liang J, Tan Q, Wang Z
Cells 2023 Feb 14;12(4)
Cells 2023 Feb 14;12(4)
METTL3 depletion contributes to tumour progression and drug resistance via N6 methyladenosine-dependent mechanism in HR+HER2-breast cancer.
Ouyang D, Hong T, Fu M, Li Y, Zeng L, Chen Q, He H, Wen Y, Cheng Y, Zhou M, Zou Q, Yi W
Breast cancer research : BCR 2023 Feb 10;25(1):19
Breast cancer research : BCR 2023 Feb 10;25(1):19
UBE2E2 enhances Snail-mediated epithelial-mesenchymal transition and Nrf2-mediated antioxidant activity in ovarian cancer.
Hong X, Ma N, Li D, Zhang M, Dong W, Huang J, Ci X, Zhang S
Cell death & disease 2023 Feb 10;14(2):100
Cell death & disease 2023 Feb 10;14(2):100
CircPTK2/PABPC1/SETDB1 axis promotes EMT-mediated tumor metastasis and gemcitabine resistance in bladder cancer.
Meng X, Xiao W, Sun J, Li W, Yuan H, Yu T, Zhang X, Dong W
Cancer letters 2023 Feb 1;554:216023
Cancer letters 2023 Feb 1;554:216023
Exosomes derived from human umbilical cord mesenchymal stem cells loaded with RVG-Lamp2b and Netrin-1 promotes Schwann cell invasion and migration.
He J, Du Z, Zhang H, Wang B, Xia J
Tissue & cell 2023 Dec;85:102219
Tissue & cell 2023 Dec;85:102219
AKAP12 inhibits esophageal squamous carcinoma cell proliferation, migration, and cell cycle via the PI3K/AKT signaling pathway.
Li X, Dong H, Zheng Y, Ding S, Li Y, Li H, Huang H, Zhong C, Xie T, Xu Y
Molecular and cellular probes 2023 Dec;72:101939
Molecular and cellular probes 2023 Dec;72:101939
Loke zupa decoction attenuates bronchial EMT-mediated airway remodelling in chronic asthma through the PI3K-Akt/HIF-1α signaling pathway.
Liu J, Li L, Han X, Chen Y, Diao J
Pharmaceutical biology 2023 Dec;61(1):1332-1342
Pharmaceutical biology 2023 Dec;61(1):1332-1342
Mechanisms of dihydromyricetin against hepatocellular carcinoma elucidated by network pharmacology combined with experimental validation.
Zhang S, Shi YN, Gu J, He P, Ai QD, Zhou XD, Wang W, Qin L
Pharmaceutical biology 2023 Dec;61(1):1108-1119
Pharmaceutical biology 2023 Dec;61(1):1108-1119
Transcriptome sequencing identifies prognostic genes involved in gastric adenocarcinoma.
Li M, Bai M, Wu Y, Yang S, Zheng L, Sun L, Yu C, Huang Y
Molecular and cellular biochemistry 2023 Dec;478(12):2891-2906
Molecular and cellular biochemistry 2023 Dec;478(12):2891-2906
Selumetinib overcomes gefitinib primary and acquired resistance by regulating MIG6/STAT3 in NSCLC.
Song X, Wang L, Tang W, Yuan L, Liu Q, Li J, Fan D
Archives of pharmacal research 2023 Dec;46(11-12):924-938
Archives of pharmacal research 2023 Dec;46(11-12):924-938
Brusatol enhances MEF2A expression to inhibit RCC progression through the Wnt signalling pathway in renal cell carcinoma.
Wang T, Zhou Y, Bao H, Liu B, Wang M, Wang L, Pan T
Journal of cellular and molecular medicine 2023 Dec;27(23):3897-3910
Journal of cellular and molecular medicine 2023 Dec;27(23):3897-3910
hsa-miR-1301-3p Promotes the Proliferation and Migration of Nonsmall Cell Lung Cancer Cells and Reduces Radiosensitivity via Targeting Homeodomain-Only Protein Homeobox.
Qu M, Jin Z, Xu Y, Sun W, Luo Y, Zhang N, Huang Z, Han L, Gong Y, Xie C
Genetic testing and molecular biomarkers 2023 Dec;27(12):393-405
Genetic testing and molecular biomarkers 2023 Dec;27(12):393-405
Isoliquiritigenin suppresses the progression of malignant melanoma via targeting H2A.Z.1-E2F1 pathway.
Xiang S, Jian L, Zeng H, Wu H, Ge B, Zhang P, Lin J, Guo A, Zhou B
Biochemical pharmacology 2023 Dec;218:115859
Biochemical pharmacology 2023 Dec;218:115859
Trigonelline inhibits tubular epithelial-mesenchymal transformation in diabetic kidney disease via targeting Smad7.
Gong M, Guo Y, Dong H, Wu W, Wu F, Lu F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115747
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Dec;168:115747
Cell-in-Cell-Mediated Entosis Reveals a Progressive Mechanism in Pancreatic Cancer.
Song J, Xu R, Zhang H, Xue X, Ruze R, Chen Y, Yin X, Wang C, Zhao Y
Gastroenterology 2023 Dec;165(6):1505-1521.e20
Gastroenterology 2023 Dec;165(6):1505-1521.e20
Hydroxypropyl-β-cyclodextrin inhibits the development of triple negative breast cancer by enhancing antitumor immunity.
Zhu M, Zhao Q, Zhang W, Xu H, Zhang B, Zhang S, Duan Y, Liao C, Yang X, Chen Y
International immunopharmacology 2023 Dec;125(Pt A):111168
International immunopharmacology 2023 Dec;125(Pt A):111168
Multi-omics analysis reveals the mechanism of action of ophiopogonin D against pulmonary fibrosis.
Bao S, Chen T, Chen J, Zhang J, Zhang G, Hui Y, Li J, Yan S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155078
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155078
CircRNA0007766 accelerates cancer progression via miR-34c-5p/cyclin D1 axis in adenocarcinoma of the esophagogastric junction (AEG).
Wu F, Guo X, Ren Y, Peng Y, Lai Z, Xu J
Cellular signalling 2023 Dec;112:110912
Cellular signalling 2023 Dec;112:110912
LncRNA MIR200CHG inhibits EMT in gastric cancer by stabilizing miR-200c from target-directed miRNA degradation.
Zhu Y, Huang C, Zhang C, Zhou Y, Zhao E, Zhang Y, Pan X, Huang H, Liao W, Wang X
Nature communications 2023 Dec 8;14(1):8141
Nature communications 2023 Dec 8;14(1):8141
ACTN1 promotes HNSCC tumorigenesis and cisplatin resistance by enhancing MYH9-dependent degradation of GSK-3β and integrin β1-mediated phosphorylation of FAK.
Cui L, Lu Y, Zheng J, Guo B, Zhao X
Journal of experimental & clinical cancer research : CR 2023 Dec 7;42(1):335
Journal of experimental & clinical cancer research : CR 2023 Dec 7;42(1):335
RUNX1 knockdown induced apoptosis and impaired EMT in high-grade serous ovarian cancer cells.
Chen Y, He Z, Yang S, Chen C, Xiong W, He Y, Liu S
Journal of translational medicine 2023 Dec 6;21(1):886
Journal of translational medicine 2023 Dec 6;21(1):886
PRRSV alters m(6)A methylation and alternative splicing to regulate immune, extracellular matrix-associated function.
Lin C, Zeng M, Song J, Li H, Feng Z, Li K, Pei Y
International journal of biological macromolecules 2023 Dec 31;253(Pt 2):126741
International journal of biological macromolecules 2023 Dec 31;253(Pt 2):126741
Sinapine thiocyanate exhibited anti-colorectal cancer effects by inhibiting KRT6A/S100A2 axis.
Yang Y, Zeng Z, Li L, Lei S, Wu Y, Chen T, Zhang J
Cancer biology & therapy 2023 Dec 31;24(1):2249170
Cancer biology & therapy 2023 Dec 31;24(1):2249170
VAMP8 suppresses the metastasis via DDX5/β-catenin signal pathway in osteosarcoma.
Yang S, Zhou P, Zhang L, Xie X, Zhang Y, Bo K, Xue J, Zhang W, Liao F, Xu P, Hu Y, Yan R, Liu D, Chang J, Zhou K
Cancer biology & therapy 2023 Dec 31;24(1):2230641
Cancer biology & therapy 2023 Dec 31;24(1):2230641
Lnc-PKNOX1-1 inhibits tumor progression in cutaneous malignant melanoma by regulating NF-κB/IL-8 axis.
Hong A, Cao M, Li D, Wang Y, Zhang G, Fang F, Zhao L, Wang Q, Lin T, Wang Y
Carcinogenesis 2023 Dec 30;44(12):871-883
Carcinogenesis 2023 Dec 30;44(12):871-883
Cell-cell and cell-matrix adhesion regulated by Piezo1 is critical for stiffness-dependent DRG neuron aggregation.
Lei M, Wang W, Zhang H, Gong J, Wang Z, Cai H, Yang X, Wang S, Ma C
Cell reports 2023 Dec 26;42(12):113522
Cell reports 2023 Dec 26;42(12):113522
DPP4 Regulates the Th17/IL-17 Axis and Accelerates Epithelial Mesenchymal Transition to Promote Ovalbumin-Induced Asthma in Female C57BL/6J Mice.
Li L, Ling F, Li R, Jiang Y, Long H, Xiao B, Wu J, Long Z, Ma L
Frontiers in bioscience (Landmark edition) 2023 Dec 26;28(12):342
Frontiers in bioscience (Landmark edition) 2023 Dec 26;28(12):342
The nucleolar protein NIFK accelerates the progression of colorectal cancer via activating MYC pathway.
Xia T, Wang B, Sun L
Bioscience, biotechnology, and biochemistry 2023 Dec 19;88(1):26-36
Bioscience, biotechnology, and biochemistry 2023 Dec 19;88(1):26-36
Histone demethylase KDM4B accelerates the progression of glioblastoma via the epigenetic regulation of MYC stability.
Wang Z, Cai H, Li Z, Sun W, Zhao E, Cui H
Clinical epigenetics 2023 Dec 13;15(1):192
Clinical epigenetics 2023 Dec 13;15(1):192
Inhibition of PFKP in renal tubular epithelial cell restrains TGF-β induced glycolysis and renal fibrosis.
Yang S, Wu H, Li Y, Li L, Xiang J, Kang L, Yang G, Liang Z
Cell death & disease 2023 Dec 12;14(12):816
Cell death & disease 2023 Dec 12;14(12):816
Therapeutic protein PAK restrains the progression of triple negative breast cancer through degrading SREBP-1 mRNA.
Hu P, Zhou P, Sun T, Liu D, Yin J, Liu L
Breast cancer research : BCR 2023 Dec 11;25(1):151
Breast cancer research : BCR 2023 Dec 11;25(1):151
Dissecting T-cell heterogeneity in esophageal squamous cell carcinoma reveals the potential role of LAIR2 in antitumor immunity.
Wang P, Zhuang W, Zheng Z, Zhang L, Zhang X, Chen Q
Clinical and experimental immunology 2023 Dec 11;214(1):36-49
Clinical and experimental immunology 2023 Dec 11;214(1):36-49
Squalene epoxidase promotes breast cancer progression by regulating CCNB1 protein stability.
Tuluhong D, Gao H, Li X, Wang L, Zhu Y, Xu C, Wang J, Li H, Li Q, Wang S
Experimental cell research 2023 Dec 1;433(1):113805
Experimental cell research 2023 Dec 1;433(1):113805
Ginsenoside Rg1 Alleviates Lipopolysaccharide-Induced Fibrosis of Endometrial Epithelial Cells in Dairy Cows by Inhibiting Reactive Oxygen Species-Activated NLRP3.
Song L, Wang L, Li X, Xiao L
Animals : an open access journal from MDPI 2023 Dec 1;13(23)
Animals : an open access journal from MDPI 2023 Dec 1;13(23)
TAGLN2 Promotes the Proliferation, Migration, Invasion, and EMT of Clear Cell Renal Cell Carcinoma Through the PI3K/Akt Signaling Pathway.
He Y, Zhang B, Han D, Du Y, Zhang X, Wang H, Yue Z, Shang P
Biochemical genetics 2023 Aug;61(4):1265-1281
Biochemical genetics 2023 Aug;61(4):1265-1281
Aquaporin 1 is a prognostic marker and inhibits tumour progression through downregulation of Snail expression in intrahepatic cholangiocarcinoma.
Zhuang MQ, Jiang XL, Liu WD, Xie QH, Wang P, Dong LW, Hu HP, Zhou HB, Zhou YB
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2023 Aug;55(8):1133-1140
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2023 Aug;55(8):1133-1140
KIF15 knockdown inhibits the development of endometrial cancer by suppressing epithelial-mesenchymal transition and stemness through Wnt/β-catenin signaling.
Huang J, Sun X, Diao G, Li R, Guo J, Han J
Environmental toxicology 2023 Aug;38(8):1824-1834
Environmental toxicology 2023 Aug;38(8):1824-1834
Withdrawal: CircKIAA1429 accelerates hepatocellular carcinoma advancement by miR-199b-5p/OTX1 pathway, by Bin Lu, Min Cheng, Tao Wang.
Journal of viral hepatitis 2023 Aug;30(8):713
ISL1 regulates lung branching morphogenesis via Shh signaling pathway.
Huang R, Zhang C, Zheng Y, Zhang W, Huang H, Qiu M, Li J, Li F
The Journal of biological chemistry 2023 Aug;299(8):105034
The Journal of biological chemistry 2023 Aug;299(8):105034
Profilin1 Regulates Trophoblast Invasion and Macrophage Differentiation.
Chen X, Song QL, Wang JY, Ji R, Li ZH, Cao ML, Mu XF, Guo DY, Zhang Y, Yang J
The American journal of pathology 2023 Aug;193(8):1059-1071
The American journal of pathology 2023 Aug;193(8):1059-1071
MALAT1 binds to miR-188-3p to regulate ALOX5 activity in the lung inflammatory response of neonatal bronchopulmonary dysplasia.
Feng DD, Chen JH, Chen YF, Cao Q, Li BJ, Chen XQ, Jin R, Zhou GP
Molecular immunology 2023 Aug;160:67-79
Molecular immunology 2023 Aug;160:67-79
Long non-coding RNA ENST00000503625 is a potential prognostic biomarker and metastasis suppressor gene in prostate cancer.
Li Y, Fang Z, Ge S, Li J, Qu L, Shi X, Zhang W, Sun Y, Ren S, Wang L
Journal of cancer research and clinical oncology 2023 Aug;149(10):7305-7317
Journal of cancer research and clinical oncology 2023 Aug;149(10):7305-7317
PRSS2 regulates EMT and metastasis via MMP-9 in gastric cancer.
Wang F, Yi J, Chen Y, Bai X, Lu C, Feng S, Zhou X
Acta histochemica 2023 Aug;125(6):152071
Acta histochemica 2023 Aug;125(6):152071
Inhibition of IL-4/STAT6/IRF4 signaling reduces the epithelial-mesenchymal transition in eosinophilic chronic rhinosinusitis with nasal polyps.
Chen J, Chen S, Gong G, Yang F, Chen J, Wang Y
International immunopharmacology 2023 Aug;121:110554
International immunopharmacology 2023 Aug;121:110554
The ALOX5 inhibitor Zileuton regulates tumor-associated macrophage M2 polarization by JAK/STAT and inhibits pancreatic cancer invasion and metastasis.
Hu WM, Liu SQ, Zhu KF, Li W, Yang ZJ, Yang Q, Zhu ZC, Chang J
International immunopharmacology 2023 Aug;121:110505
International immunopharmacology 2023 Aug;121:110505
ROS Scavenging Nanozyme Modulates Immunosuppression for Sensitized Cancer Immunotherapy.
Mo W, Liu S, Zhao X, Wei F, Li Y, Sheng X, Cao W, Ding M, Zhang W, Chen X, Meng L, Yao S, Diao W, Wei H, Guo H
Advanced healthcare materials 2023 Aug;12(21):e2300191
Advanced healthcare materials 2023 Aug;12(21):e2300191
ZDHHC11B is decreased in lung adenocarcinoma and inhibits tumorigenesis via regulating epithelial-mesenchymal transition.
Dai H, Wu R, Zhang J, Dou R, Xu M, Wang J, Wang J, Su F, Zhang T
Cancer medicine 2023 Aug;12(16):17212-17222
Cancer medicine 2023 Aug;12(16):17212-17222
Glutamine and amino acid metabolism as a prognostic signature and therapeutic target in endometrial cancer.
Zhai L, Yang X, Cheng Y, Wang J
Cancer medicine 2023 Aug;12(15):16337-16358
Cancer medicine 2023 Aug;12(15):16337-16358
Hypoxic tumor-derived exosomal miR-21 induces cancer-associated fibroblast activation to promote head and neck squamous cell carcinoma metastasis.
Ye B, Duan Y, Zhou M, Wang Y, Lai Q, Yue K, Cao J, Wu Y, Wang X, Jing C
Cellular signalling 2023 Aug;108:110725
Cellular signalling 2023 Aug;108:110725
NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β/Smad signaling pathways in diabetic nephropathy.
Qiu D, Song S, Chen N, Bian Y, Yuan C, Zhang W, Duan H, Shi Y
Cellular signalling 2023 Aug;108:110712
Cellular signalling 2023 Aug;108:110712
Cancer-associated fibroblasts in the invasive tumour front promote the metastasis of oral squamous cell carcinoma through MFAP5 upregulation.
Wang Y, Wang R, Li B, Huang Z, Zhao S, Chen S, Lan T, Ren S, Wu F, Tan J, Li J
Gene 2023 Aug 5;876:147504
Gene 2023 Aug 5;876:147504
SMC1A facilitates gastric cancer cell proliferation, migration, and invasion via promoting SNAIL activated EMT.
Liu Y, Fang X, Wang Q, Xiao D, Zhou T, Kang K, Peng Z, Ren F, Zhou J
BMC gastroenterology 2023 Aug 4;23(1):268
BMC gastroenterology 2023 Aug 4;23(1):268
High Thioredoxin Domain-Containing Protein 11 Expression Is Associated with Tumour Progression in Glioma.
Chen YT, Chung CL, Cheng YW, Lin CJ, Tseng TT, Hsu SS, Tsai HP, Kwan AL
International journal of molecular sciences 2023 Aug 29;24(17)
International journal of molecular sciences 2023 Aug 29;24(17)
Mutations in CCNB3 affect its location thus causing a multiplicity of phenotypes in human oocytes maturation by aberrant CDK1 activity and APC/C activity at different stages.
Wang C, Chen MX, Zhang Y, Bai X, Cao Q, Han J, Zhang N, Zhao C, Ling X, Rui X, Guan Y, Zhang J, Huo R
Journal of ovarian research 2023 Aug 28;16(1):178
Journal of ovarian research 2023 Aug 28;16(1):178
Acetyl-cinobufagin suppresses triple-negative breast cancer progression by inhibiting the STAT3 pathway.
Qi Y, Wu H, Zhu T, Liu Z, Liu C, Yan C, Wu Z, Xu Y, Bai Y, Yang L, Cheng D, Zhang X, Zhao H, Zhao C, Dai X
Aging 2023 Aug 28;15(16):8258-8274
Aging 2023 Aug 28;15(16):8258-8274
Orosomucoid 1 promotes colorectal cancer progression and liver metastasis by affecting PI3K/AKT pathway and inducing macrophage M2 polarization.
Yue L, Xu X, Dai S, Xu F, Zhao W, Gu J, Dai X, Qian X
Scientific reports 2023 Aug 28;13(1):14092
Scientific reports 2023 Aug 28;13(1):14092
MiR-297 inhibits tumour progression of liver cancer by targeting PTBP3.
Lu N, Min J, Peng L, Huang S, Chai X, Wang S, Wang J
Cell death & disease 2023 Aug 26;14(8):564
Cell death & disease 2023 Aug 26;14(8):564
PHF23 promotes NSCLC proliferation, metastasis, and chemoresistance via stabilization of ACTN4 and activation of the ERK pathway.
Cheng M, Cao H, Yao P, Guan J, Wu P, Ji H, Jiang S, Yuan Y, Fu L, Zheng Q, Li Q
Cell death & disease 2023 Aug 25;14(8):558
Cell death & disease 2023 Aug 25;14(8):558
UCP1 alleviates renal interstitial fibrosis progression through oxidative stress pathway mediated by SIRT3 protein stability.
Xiong W, Xiong Z, Song A, Lei C, Ye C, Su H, Zhang C
Journal of translational medicine 2023 Aug 2;21(1):521
Journal of translational medicine 2023 Aug 2;21(1):521
Purple Yam Polyphenol Extracts Exert Anticolitis and Anticolitis-Associated Colorectal Cancer Effects through Inactivation of NF-κB/p65 and STAT3 Signaling Pathways.
Yang X, Wang Q, Zhang X, Li L, Cao X, Zhou L, Huang Y, Sun G, Chen Y
Journal of agricultural and food chemistry 2023 Aug 16;71(32):12177-12189
Journal of agricultural and food chemistry 2023 Aug 16;71(32):12177-12189
Transforms of Cell Surface Glycoproteins Charge Influences Tumor Cell Metastasis via Atypically Inhibiting Epithelial-Mesenchymal Transition Including Matrix Metalloproteinases and Cell Junctions.
Wang M, Kejian S, Ye L, Chen J, Ma L
Bioconjugate chemistry 2023 Aug 16;34(8):1498-1507
Bioconjugate chemistry 2023 Aug 16;34(8):1498-1507
ADAMDEC1 induces EMT and promotes colorectal cancer cells metastasis by enhancing Wnt/β-catenin signaling via negative modulation of GSK-3β.
Jia Y, Huang X, Shi H, Wang M, Chen J, Zhang H, Hou D, Jing H, Du J, Han H, Zhang J
Experimental cell research 2023 Aug 15;429(2):113629
Experimental cell research 2023 Aug 15;429(2):113629
Claudin-3 facilitates the progression and mediates the tumorigenic effects of TGF-β in glioblastoma multiforme.
Sun Z, Yan T, Jiang H, Cai J, Zhu X, Chen Q
Medical oncology (Northwood, London, England) 2023 Aug 14;40(9):268
Medical oncology (Northwood, London, England) 2023 Aug 14;40(9):268
Ubiquitin-specific protease 7 prevents recurrent spontaneous abortion by targeting enhancer of zeste homolog 2 to regulate trophoblast proliferation, apoptosis, migration, and invasion through the Wnt/β-catenin pathway†.
Zhou M, Gao Y, Wu S, Chen J, Ding J, Wang Y, Yang J
Biology of reproduction 2023 Aug 10;109(2):204-214
Biology of reproduction 2023 Aug 10;109(2):204-214
Comprehensive bioinformatics and experimental analysis of SH3PXD2B reveals its carcinogenic effect in gastric carcinoma.
Zhu Y, Hu Y, Wang P, Dai X, Fu Y, Xia Y, Sun L, Ruan S
Life sciences 2023 Aug 1;326:121792
Life sciences 2023 Aug 1;326:121792
Circular RNA Sec61 subunit alpha isoform 1 by competitive absorption of microRNA-513a-5p mediates peroxisomal biogenesis factor 5 expression and promotes the malignant phenotype of non-small cell lung cancer.
Duan ZP, Yu XJ, Wei HL
The Kaohsiung journal of medical sciences 2023 Apr;39(4):326-336
The Kaohsiung journal of medical sciences 2023 Apr;39(4):326-336
ADAMTS12 promotes migration and epithelial-mesenchymal transition and predicts poor prognosis for pancreatic cancer.
He RZ, Zheng JH, Yao HF, Xu DP, Yang MW, Liu DJ, Sun YW, Huo YM
Hepatobiliary & pancreatic diseases international : HBPD INT 2023 Apr;22(2):169-178
Hepatobiliary & pancreatic diseases international : HBPD INT 2023 Apr;22(2):169-178
XPO1 intensifies sorafenib resistance by stabilizing acetylation of NPM1 and enhancing epithelial-mesenchymal transition in hepatocellular carcinoma.
Wang Z, Pan B, Yao Y, Qiu J, Zhang X, Wu X, Tang N
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Apr;160:114402
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Apr;160:114402
Budding uninhibited by benzimidazoles 1 overexpression is associated with poor prognosis and malignant phenotype: A promising therapeutic target for lung adenocarcinoma.
Chen R, Wang Z, Lu T, Liu Y, Ji Y, Yu Y, Tou F, Guo S
Thoracic cancer 2023 Apr;14(10):893-912
Thoracic cancer 2023 Apr;14(10):893-912
ETV4 Mediated Tumor-Associated Neutrophil Infiltration Facilitates Lymphangiogenesis and Lymphatic Metastasis of Bladder Cancer.
Zhang Q, Liu S, Wang H, Xiao K, Lu J, Chen S, Huang M, Xie R, Lin T, Chen X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(11):e2205613
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(11):e2205613
Radiation induces IRAK1 expression to promote radioresistance by suppressing autophagic cell death via decreasing the ubiquitination of PRDX1 in glioma cells.
Li J, Sun Y, Zhao X, Ma Y, Xie Y, Liu S, Hui B, Shi X, Sun X, Zhang X
Cell death & disease 2023 Apr 8;14(4):259
Cell death & disease 2023 Apr 8;14(4):259
A potential link between fibroblast growth factor-23 and the progression of AKI to CKD.
Lu Y, Xu S, Tang R, Han C, Zheng C
BMC nephrology 2023 Apr 4;24(1):87
BMC nephrology 2023 Apr 4;24(1):87
Dissecting Rubella Placental Infection in an In Vitro Trophoblast Model.
Schulz J, Schilling E, Fabian C, Zenclussen AC, Stojanovska V, Claus C
International journal of molecular sciences 2023 Apr 26;24(9)
International journal of molecular sciences 2023 Apr 26;24(9)
Targeting BRD3 eradicates nuclear TYRO3-induced colorectal cancer metastasis.
Hsu PL, Chien CW, Tang YA, Lin BW, Lin SC, Lin YS, Chen SY, Sun HS, Tsai SJ
Science advances 2023 Apr 14;9(15):eade3422
Science advances 2023 Apr 14;9(15):eade3422
EPC-exosomal miR-26a-5p improves airway remodeling in COPD by inhibiting ferroptosis of bronchial epithelial cells via PTGS2/PGE2 signaling pathway.
Liu C, Lu J, Yuan T, Xie L, Zhang L
Scientific reports 2023 Apr 14;13(1):6126
Scientific reports 2023 Apr 14;13(1):6126
LINC00365 functions as a tumor suppressor by inhibiting HIF-1α-mediated glucose metabolism reprogramming in breast cancer.
Liu B, Qu X, Wang J, Xu L, Zhang L, Xu B, Su J, Bian X
Experimental cell research 2023 Apr 1;425(1):113514
Experimental cell research 2023 Apr 1;425(1):113514
Aristolochic acid I promotes the invasion and migration of hepatocellular carcinoma cells by activating the C3a/C3aR complement system.
Li Y, Zhu S, Xue M, Jing Y, Liu X, Cai D, Zhao Y, Bian Y, Zhang Z, Zhang L
Toxicology letters 2023 Apr 1;378:51-60
Toxicology letters 2023 Apr 1;378:51-60
CMTM6 as a candidate risk gene for cervical cancer: Comprehensive bioinformatics study.
Huang X, Liu W, Liu C, Hu J, Wang B, Ren A, Huang X, Yuan Y, Liu J, Li M
Frontiers in molecular biosciences 2022;9:983410
Frontiers in molecular biosciences 2022;9:983410
Lactobacillus fermentum CECT5716 Alleviates the Inflammatory Response in Asthma by Regulating TLR2/TLR4 Expression.
Wang W, Li Y, Han G, Li A, Kong X
Frontiers in nutrition 2022;9:931427
Frontiers in nutrition 2022;9:931427
TRIM47 promotes ovarian cancer cell proliferation, migration, and invasion by activating STAT3 signaling.
Wang X, Fu Y, Xing Y
Clinics (Sao Paulo, Brazil) 2022;77:100122
Clinics (Sao Paulo, Brazil) 2022;77:100122
Ginsenoside Rd inhibits migration and invasion of tongue cancer cells through H19/miR-675-5p/CDH1 axis.
Chang L, Wang D, Kan S, Hao M, Liu H, Yang Z, Xia Q, Liu W
Journal of applied oral science : revista FOB 2022;30:e20220144
Journal of applied oral science : revista FOB 2022;30:e20220144
Non-canonical Small GTPase RBJ Promotes NSCLC Progression Through the Canonical MEK/ERK Signaling Pathway.
Wang Y, Shen X, Wang Q, Guo Z, Hu L, Dong Z, Hu W
Current pharmaceutical design 2022;28(42):3446-3455
Current pharmaceutical design 2022;28(42):3446-3455
IL-33 Participates in the Development of Esophageal Adenocarcinoma.
Liu J, Liu L, Su Y, Wang Y, Zhu Y, Sun X, Guo Y, Shan J
Pathology oncology research : POR 2022;28:1610474
Pathology oncology research : POR 2022;28:1610474
Carbon Monoxide-Releasing Molecule-3 Suppresses the Malignant Biological Behavior of Tongue Squamous Cell Carcinoma via Regulating Keap1/Nrf2/HO-1 Signaling Pathway.
Dai Y, Chen H, Pan Y, Song H
BioMed research international 2022;2022:9418332
BioMed research international 2022;2022:9418332
PHGDH Inhibitor CBR-5884 Inhibits Epithelial Ovarian Cancer Progression via ROS/Wnt/β-Catenin Pathway and Plays a Synergistic Role with PARP Inhibitor Olaparib.
Zhang X, Sun M, Jiao Y, Lin B, Yang Q
Oxidative medicine and cellular longevity 2022;2022:9029544
Oxidative medicine and cellular longevity 2022;2022:9029544
IMP4 Silencing Inhibits the Malignancy of Lung Adenocarcinoma via ERK Pathway.
Li R, Han Z, Ma W, Zhang L, Zhang X, Jiang Y, Dong W
Journal of oncology 2022;2022:8545441
Journal of oncology 2022;2022:8545441
Keratin 8 Is an Inflammation-Induced and Prognosis-Related Marker for Pancreatic Adenocarcinoma.
Xiong F, Guo T, Wang X, Wu G, Liu W, Wang Q, Wang B, Chen Y
Disease markers 2022;2022:8159537
Disease markers 2022;2022:8159537
JPHYD Inhibits miR-21-5p/Smad7-Mediated Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma Cells.
Liu LH, Fang CK, Ge FC, Wang JN, Zhang XB, Luo R, Zhang Y, Feng KL, Qiu ZW, Zhong C
Journal of oncology 2022;2022:7823433
Journal of oncology 2022;2022:7823433
Xiaotan Sanjie Decoction Inhibits Gastric Cancer Cell Proliferation, Migration, and Invasion through lncRNA-ATB and miR-200A.
Zhou Z, Chen J, Li M, Cao L, Chen M, Zhang Q, Yu Z, Chai K
BioMed research international 2022;2022:7029182
BioMed research international 2022;2022:7029182
Pygo1 Regulates the Behavior of Human Non-Small-Cell Lung Cancer via the Wnt/β-Catenin Pathway.
Wen Y, Li Y, Yang B, Guo X, Lin L, Liang J, Zhang K, Li X, Jiang Z, Wang Y, Li Y, Wu X, Fan X, Li F, Yuan W
Disease markers 2022;2022:6993994
Disease markers 2022;2022:6993994
Comprehensive Pan-Cancer Analysis of IRAK Family Genes Identifies IRAK1 as a Novel Oncogene in Low-Grade Glioma.
Li J, Sun Y, Ma Y, Zhao X, Sun X, Wang Y, Zhang X
Journal of oncology 2022;2022:6497241
Journal of oncology 2022;2022:6497241
Multifunctional Drug-Loaded Phase-Change Nanoparticles Inhibit the Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma by Affecting the Activity of Activated Hepatic Stellate Cells.
Zou X, Li T, Mao Y, Zhu M, Chen X, Niu J, Dong T, Jiang J, Yang X
BioMed research international 2022;2022:6441179
BioMed research international 2022;2022:6441179
The Gut Microbiota Dysbiosis in Preeclampsia Contributed to Trophoblast Cell Proliferation, Invasion, and Migration via lncRNA BC030099/NF-κB Pathway.
Tang R, Xiao G, Jian Y, Yuan Q, Jiang C, Wang W
Mediators of inflammation 2022;2022:6367264
Mediators of inflammation 2022;2022:6367264
Blocking REDD1/TXNIP Complex Ameliorates HG-Induced Renal Tubular Epithelial Cell Apoptosis and EMT through Repressing Oxidative Stress.
Mu L, Chen N, Chen Y, Yang Z, Zhou H, Song S, Shi Y
International journal of endocrinology 2022;2022:6073911
International journal of endocrinology 2022;2022:6073911
TNFAIP6 Promotes Gastric Carcinoma Cell Invasion via Upregulating PTX3 and Activating the Wnt/β-Catenin Signaling Pathway.
Cui H, Zhang L, Chen B, Zhang F, Xu H, Ma G, Cao L, Wang M
Contrast media & molecular imaging 2022;2022:5697034
Contrast media & molecular imaging 2022;2022:5697034
ASPM Promotes the Progression of Anaplastic Thyroid Carcinomas by Regulating the Wnt/β-Catenin Signaling Pathway.
Jiang L, Zhang S, An N, Chai G, Ye C
International journal of endocrinology 2022;2022:5316102
International journal of endocrinology 2022;2022:5316102
CYP26A1 Is a Novel Cancer Biomarker of Pancreatic Carcinoma: Evidence from Integration Analysis and In Vitro Experiments.
Yu Y, Wang Y, Zou Y, Yu Y
Disease markers 2022;2022:5286820
Disease markers 2022;2022:5286820
HO-1 Contributes to Luteolin-Triggered Ferroptosis in Clear Cell Renal Cell Carcinoma via Increasing the Labile Iron Pool and Promoting Lipid Peroxidation.
Han S, Lin F, Qi Y, Liu C, Zhou L, Xia Y, Chen K, Xing J, Liu Z, Yu W, Zhang Y, Zhou X, Rao T, Cheng F
Oxidative medicine and cellular longevity 2022;2022:3846217
Oxidative medicine and cellular longevity 2022;2022:3846217
Panax Notoginseng Saponins Regulate Transforming Growth Factor-β1 through MAPK and Snail/TWIST1 Signaling Pathway to Inhibit Epithelial-Mesenchymal Transition of Pulmonary Fibrosis in A549 Cells.
Nguyen V, Pan F, Zhang G, Zhang Q, Lu Y
Evidence-based complementary and alternative medicine : eCAM 2022;2022:3744618
Evidence-based complementary and alternative medicine : eCAM 2022;2022:3744618
Prognostic Lnc-S100B-2 Affects Cell Apoptosis and Microenvironment of Colorectal Cancer through MLLT10 Signaling.
Yi J, Peng F, Zhao J, Gong X
Journal of oncology 2022;2022:3565118
Journal of oncology 2022;2022:3565118
Biochanin A Suppresses Tumor Progression and PD-L1 Expression via Inhibiting ZEB1 Expression in Colorectal Cancer.
Xu J, Yang X, Pan J, Fan H, Mei J, Hua D
Journal of oncology 2022;2022:3224373
Journal of oncology 2022;2022:3224373
Fluorofenidone Inhibits UUO/IRI-Induced Renal Fibrosis by Reducing Mitochondrial Damage.
Liao X, Lv X, Zhang Y, Han Y, Li J, Zeng J, Tang D, Meng J, Yuan X, Peng Z, Tao L, Xie Y
Oxidative medicine and cellular longevity 2022;2022:2453617
Oxidative medicine and cellular longevity 2022;2022:2453617
Upregulated LINC00922 Promotes Epithelial-Mesenchymal Transition and Indicates a Dismal Prognosis in Gastric Cancer.
Chen X, Hu L, Mao X, Chen H, She Y, Chi H, Zeng H, Guo L, Han Y
Journal of oncology 2022;2022:1608936
Journal of oncology 2022;2022:1608936
Novel lncRNA AL033381.2 Promotes Hepatocellular Carcinoma Progression by Upregulating PRKRA Expression.
Wang F, Zhu L, Xue Q, Tang C, Tang W, Zhang N, Dai C, Chen Z
Oxidative medicine and cellular longevity 2022;2022:1125932
Oxidative medicine and cellular longevity 2022;2022:1125932
ROS Promote Hypoxia-Induced Keratinocyte Epithelial-Mesenchymal Transition by Inducing SOX2 Expression and Subsequent Activation of Wnt/β-Catenin.
Shi Y, Wang S, Yang R, Wang Z, Zhang W, Liu H, Huang Y
Oxidative medicine and cellular longevity 2022;2022:1084006
Oxidative medicine and cellular longevity 2022;2022:1084006
Upregulation of SQLE Contributes to Poor Survival in Head and Neck Squamous Cell Carcinoma.
Li J, Yang T, Wang Q, Li Y, Wu H, Zhang M, Qi H, Zhang H, Li J
International journal of biological sciences 2022;18(9):3576-3591
International journal of biological sciences 2022;18(9):3576-3591
UBE2S as a novel ubiquitinated regulator of p16 and β-catenin to promote bone metastasis of prostate cancer.
Peng S, Chen X, Huang C, Yang C, Situ M, Zhou Q, Ling Y, Huang H, Huang M, Zhang Y, Cheng L, Zhang Q, Guo Z, Lai Y, Huang J
International journal of biological sciences 2022;18(8):3528-3543
International journal of biological sciences 2022;18(8):3528-3543
USP1 inhibition suppresses the progression of osteosarcoma via destabilizing TAZ.
Yuan P, Feng Z, Huang H, Wang G, Chen Z, Xu G, Xie Z, Jie Z, Zhao X, Ma Q, Wang S, Shen Y, Huang Y, Han Y, Ye H, Wang J, Shi P, Sun X
International journal of biological sciences 2022;18(8):3122-3136
International journal of biological sciences 2022;18(8):3122-3136
USF1-ATRAP-PBX3 Axis Promote Breast Cancer Glycolysis and Malignant Phenotype by Activating AKT/mTOR Signaling.
Wang D, Jin X, Lei M, Jiang Y, Liu Y, Yu F, Guo Y, Han B, Yang Y, Sun W, Liu Y, Zeng G, Liu F, Hu J, Chen X
International journal of biological sciences 2022;18(6):2452-2471
International journal of biological sciences 2022;18(6):2452-2471
Poly (ADP-ribose) polymerase 1 (PARP1) inhibition promotes pulmonary metastasis of osteosarcoma by boosting ezrin phosphorylation.
Li F, Wu X, Fu X, Liu J, Song W, Xiao GG, Lu A, Zhang G
International journal of biological sciences 2022;18(3):1238-1253
International journal of biological sciences 2022;18(3):1238-1253
TBL1X and Flot2 form a positive feedback loop to promote metastasis in nasopharyngeal carcinoma.
Xu H, Yan X, Zhu H, Kang Y, Luo W, Zhao J, Zhou K, Liu X, Ye L, Zhou Q, Li S, Zhao M, Wang L, Zhu B, Liu W, Li J, Jiang X, Ren C
International journal of biological sciences 2022;18(3):1134-1149
International journal of biological sciences 2022;18(3):1134-1149
Decrease of circARID1A retards glioblastoma invasion by modulating miR-370-3p/ TGFBR2 pathway.
Li B, Chen J, Wu Y, Luo H, Ke Y
International journal of biological sciences 2022;18(13):5123-5135
International journal of biological sciences 2022;18(13):5123-5135
Human CPTP promotes growth and metastasis via sphingolipid metabolite ceramide and PI4KA/AKT signaling in pancreatic cancer cells.
Zhang Y, Ji S, Zhang X, Lu M, Hu Y, Han Y, Shui G, Lam SM, Zou X
International journal of biological sciences 2022;18(13):4963-4983
International journal of biological sciences 2022;18(13):4963-4983
Interaction between BEND5 and RBPJ suppresses breast cancer growth and metastasis via inhibiting Notch signaling.
Shi Y, Zhang D, Chen J, Jiang Q, Song S, Mi Y, Wang T, Ye Q
International journal of biological sciences 2022;18(10):4233-4244
International journal of biological sciences 2022;18(10):4233-4244
RNA-binding motif protein 10 represses tumor progression through the Wnt/β- catenin pathway in lung adenocarcinoma.
Cao Y, Geng J, Wang X, Meng Q, Xu S, Lang Y, Zhou Y, Qi L, Wang Z, Wei Z, Yu Y, Jin S, Pan B
International journal of biological sciences 2022;18(1):124-139
International journal of biological sciences 2022;18(1):124-139
NR4A1 inhibits the epithelial-mesenchymal transition of hepatic stellate cells: Involvement of TGF-β-Smad2/3/4-ZEB signaling.
Huang Q, Xu J, Ge Y, Shi Y, Wang F, Zhu M
Open life sciences 2022;17(1):447-454
Open life sciences 2022;17(1):447-454
Smurf2 suppresses the metastasis of hepatocellular carcinoma via ubiquitin degradation of Smad2.
Song D, Li S, Ning L, Zhang S, Cai Y
Open medicine (Warsaw, Poland) 2022;17(1):384-396
Open medicine (Warsaw, Poland) 2022;17(1):384-396
Clotrimazole Inhibits HCC Migration and Invasion by Modulating the ERK-p65 Signaling Pathway.
Liu X, Gao J, Sun Y, Zhang F, Guo W, Zhang S
Drug design, development and therapy 2022;16:863-871
Drug design, development and therapy 2022;16:863-871
Metformin Ameliorates Epithelial-Mesenchymal Transition of Renal Tubular Epithelial Cells in Diabetes by Increasing Vitamin D Receptor Expression.
Wen W, Huang B, Ye S
Diabetes, metabolic syndrome and obesity : targets and therapy 2022;15:4001-4010
Diabetes, metabolic syndrome and obesity : targets and therapy 2022;15:4001-4010
Mechanism of Thunberg Fritillaria in treating endometriosis based on network pharmacology and the effect of Peiminine on the MEK/ERK pathway.
Peng X, Xia Y, Xie J, Liu H, Fan L, Yu C, Ni X
American journal of translational research 2022;14(9):6196-6209
American journal of translational research 2022;14(9):6196-6209
LncRNA PCAT7 promotes non-small cell lung cancer progression by activating miR-486-5p/CDK4 axis-mediated cell cycle.
Geng W, Qiu M, Zhang D, Li P, Sun G, Zhou X
American journal of translational research 2022;14(5):3003-3016
American journal of translational research 2022;14(5):3003-3016
TMEM158 Regulates the Canonical and Non-Canonical Pathways of TGF-β to Mediate EMT in Triple-Negative Breast Cancer.
Tong J, Li H, Hu Y, Zhao Z, Li M
Journal of Cancer 2022;13(8):2694-2704
Journal of Cancer 2022;13(8):2694-2704
Sinapine Thiocyanate Inhibits the Proliferation and Mobility of Pancreatic Cancer Cells by Up-Regulating GADD45A.
Wang J, Zeng Z, Lei S, Han J, Liao S, Zhang J, Wang L, Dong Y, Li H, Chen T
Journal of Cancer 2022;13(4):1229-1240
Journal of Cancer 2022;13(4):1229-1240
2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside ameliorates bleomycin-induced pulmonary fibrosis via regulating pro-fibrotic signaling pathways.
Huang TT, Chen CM, Chen LG, Lan YW, Huang TH, Choo KB, Chong KY
Frontiers in pharmacology 2022;13:997100
Frontiers in pharmacology 2022;13:997100
NRF2-directed PRPS1 upregulation to promote the progression and metastasis of melanoma.
Xiong G, Feng Y, Yi X, Zhang X, Li X, Yang L, Yi Z, Sai B, Yang Z, Zhang Q, Kuang Y, Zhu Y
Frontiers in immunology 2022;13:989263
Frontiers in immunology 2022;13:989263
Therapeutic effect and mechanism of combination therapy with ursolic acid and insulin on diabetic nephropathy in a type I diabetic rat model.
Liu Y, Zheng JY, Wei ZT, Liu SK, Sun JL, Mao YH, Xu YD, Yang Y
Frontiers in pharmacology 2022;13:969207
Frontiers in pharmacology 2022;13:969207
Identification and validation of an immune signature associated with EMT and metabolic reprogramming for predicting prognosis and drug response in bladder cancer.
Zhang Z, Yu Y, Li P, Wang M, Jiao W, Liang Y, Niu H
Frontiers in immunology 2022;13:954616
Frontiers in immunology 2022;13:954616
A comprehensively prognostic and immunological analysis of actin-related protein 2/3 complex subunit 5 in pan-cancer and identification in hepatocellular carcinoma.
Huang S, Sun L, Hou P, Liu K, Wu J
Frontiers in immunology 2022;13:944898
Frontiers in immunology 2022;13:944898
TIM-4 in macrophages contributes to nasal polyp formation through the TGF-β1-mediated epithelial to mesenchymal transition in nasal epithelial cells.
Qin D, Liu P, Zhou H, Jin J, Gong W, Liu K, Chen S, Huang J, Fan W, Tao Z, Xu Y
Frontiers in immunology 2022;13:941608
Frontiers in immunology 2022;13:941608
The Potential Role of CDH1 as an Oncogene Combined With Related miRNAs and Their Diagnostic Value in Breast Cancer.
Xie D, Chen Y, Wan X, Li J, Pei Q, Luo Y, Liu J, Ye T
Frontiers in endocrinology 2022;13:916469
Frontiers in endocrinology 2022;13:916469
ATP-citrate lyase inhibitor improves ectopic lipid accumulation in the kidney in a db/db mouse model.
Zhan Z, Li A, Zhang W, Wu X, He J, Li Z, Li Y, Sun J, Zhang H
Frontiers in endocrinology 2022;13:914865
Frontiers in endocrinology 2022;13:914865
Dandelion Seed Extract Affects Tumor Progression and Enhances the Sensitivity of Cisplatin in Esophageal Squamous Cell Carcinoma.
Li Y, Deng Y, Zhang X, Fu H, Han X, Guo W, Zhao W, Zhao X, Yu C, Li H, Lei K, Wang T
Frontiers in pharmacology 2022;13:897465
Frontiers in pharmacology 2022;13:897465
Acteoside attenuates RSV-induced lung injury by suppressing necroptosis and regulating metabolism.
Ling X, Zhou J, Jin T, Xu W, Sun X, Li W, Ding Y, Liang M, Zhu C, Zhao P, Hu C, Yuan B, Xie T, Tao J
Frontiers in pharmacology 2022;13:870928
Frontiers in pharmacology 2022;13:870928
Crosstalk of Histone and RNA Modifications Identified a Stromal-Activated Subtype with Poor Survival and Resistance to Immunotherapy in Gastric Cancer.
Yuan C, Zhang J, Deng C, Xia Y, Li B, Meng S, Jin X, Cheng L, Li H, Zhang C, He Y
Frontiers in pharmacology 2022;13:868830
Frontiers in pharmacology 2022;13:868830
Neutrophil Extracellular Traps (NETs) Promote Non-Small Cell Lung Cancer Metastasis by Suppressing lncRNA MIR503HG to Activate the NF-κB/NLRP3 Inflammasome Pathway.
Wang Y, Liu F, Chen L, Fang C, Li S, Yuan S, Qian X, Yin Y, Yu B, Fu B, Zhang X, Li Y
Frontiers in immunology 2022;13:867516
Frontiers in immunology 2022;13:867516
KIFC3 Promotes Proliferation, Migration, and Invasion in Colorectal Cancer via PI3K/AKT/mTOR Signaling Pathway.
Liao H, Zhang L, Lu S, Li W, Dong W
Frontiers in genetics 2022;13:848926
Frontiers in genetics 2022;13:848926
Gut Dysbiosis Is Associated With the Severity of Cryptogenic Stroke and Enhanced Systemic Inflammatory Response.
Zheng Q, Chen Y, Zhai Y, Meng L, Liu H, Tian H, Feng R, Wang J, Zhang R, Sun K, Gao L, Wang Y, Wang X, Wu E, Teng J, Ding X
Frontiers in immunology 2022;13:836820
Frontiers in immunology 2022;13:836820
S100A4/TCF Complex Transcription Regulation Drives Epithelial-Mesenchymal Transition in Chronic Sinusitis Through Wnt/GSK-3β/β-Catenin Signaling.
Gong N, Shi L, Bing X, Li H, Hu H, Zhang P, Yang H, Guo N, Du H, Xia M, Liu C
Frontiers in immunology 2022;13:835888
Frontiers in immunology 2022;13:835888
NCKAP1 is a Prognostic Biomarker for Inhibition of Cell Growth in Clear Cell Renal Cell Carcinoma.
Chen J, Ge J, Zhang W, Xie X, Zhong X, Tang S
Frontiers in genetics 2022;13:764957
Frontiers in genetics 2022;13:764957
Comprehensive analysis of a glycolysis and cholesterol synthesis-related genes signature for predicting prognosis and immune landscape in osteosarcoma.
Xu F, Yan J, Peng Z, Liu J, Li Z
Frontiers in immunology 2022;13:1096009
Frontiers in immunology 2022;13:1096009
Dysfunction of CCR1(+) decidual macrophages is a potential risk factor in the occurrence of unexplained recurrent pregnancy loss.
Sang Y, Li Y, Xu L, Chen J, Li D, Du M
Frontiers in immunology 2022;13:1045532
Frontiers in immunology 2022;13:1045532
Protective effects of mefunidone on ischemia-reperfusion injury/Folic acid-induced acute kidney injury.
Li J, Jiang Y, Dai Q, Yu Y, Lv X, Zhang Y, Liao X, Ao L, Hu G, Meng J, Peng Z, Tao L, Xie Y
Frontiers in pharmacology 2022;13:1043945
Frontiers in pharmacology 2022;13:1043945
METTL3/m(6)A/IFIT2 regulates proliferation, invasion and immunity in esophageal squamous cell carcinoma.
Ge F, Li Z, Hu J, Pu Y, Zhao F, Kong L
Frontiers in pharmacology 2022;13:1002565
Frontiers in pharmacology 2022;13:1002565
COA3 overexpression promotes non-small cell lung cancer metastasis by reprogramming glucose metabolism.
Lin H, Gao Y, Sun K, Zhang Q, Li Y, Chen M, Jin F
American journal of cancer research 2022;12(8):3662-3678
American journal of cancer research 2022;12(8):3662-3678
The homeostatic malfunction of a novel feedback pathway formed by lncRNA021545, miR-330-3p and epiregulin contributes in hepatocarcinoma progression via mediating epithelial-mesenchymal transition.
Yang S, Zhang Y, Guo C, Liu R, Elkharti M, Ge Z, Liu Q, Liu S, Sun MZ
American journal of cancer research 2022;12(6):2492-2525
American journal of cancer research 2022;12(6):2492-2525
Decreased RNA m(6)A methylation enhances the process of the epithelial mesenchymal transition and vasculogenic mimicry in glioblastoma.
Tao M, Li X, He L, Rong X, Wang H, Pan J, Lu Z, Zhang X, Peng Y
American journal of cancer research 2022;12(2):893-906
American journal of cancer research 2022;12(2):893-906
The N(6)-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2.
Li B, Zhao R, Qiu W, Pan Z, Zhao S, Qi Y, Qiu J, Zhang S, Guo Q, Fan Y, Xu H, Li M, Li G, Xue H
Theranostics 2022;12(14):6363-6379
Theranostics 2022;12(14):6363-6379
Interleukin-17 promotes the development of ovarian cancer through upregulation of MTA1 expression.
Guo N, Zhang J
American journal of cancer research 2022;12(12):5646-5656
American journal of cancer research 2022;12(12):5646-5656
RUNX2 facilitates aggressiveness and chemoresistance of triple negative breast cancer cells via activating MMP1.
Si W, Xu X, Wan L, Lv F, Wei W, Xu X, Li W, Huang D, Zhang L, Li F
Frontiers in oncology 2022;12:996080
Frontiers in oncology 2022;12:996080
bub1 as a potential oncogene and a prognostic biomarker for neuroblastoma.
Song J, Ni C, Dong X, Sheng C, Qu Y, Zhu L
Frontiers in oncology 2022;12:988415
Frontiers in oncology 2022;12:988415
A novel epithelial-mesenchymal transition (EMT)-related gene signature of predictive value for the survival outcomes in lung adenocarcinoma.
Cui Y, Wang X, Zhang L, Liu W, Ning J, Gu R, Cui Y, Cai L, Xing Y
Frontiers in oncology 2022;12:974614
Frontiers in oncology 2022;12:974614
Novel LncRNA ZFHX4-AS1 as a Potential Prognostic Biomarker That Affects the Immune Microenvironment in Ovarian Cancer.
Wang X, Wang Y, Sun F, Xu Y, Zhang Z, Yang C, Zhang L, Lou G
Frontiers in oncology 2022;12:945518
Frontiers in oncology 2022;12:945518
The Novel LncRNA WASH5P Inhibits Colorectal Cancer Carcinogenesis via Targeting AKT Signaling Pathway.
Wei H, Mao T, Zhang Q, Ren K, Qi X, Zhang Y, Cao B, Jin Y, Tian Z, Ren L
Frontiers in oncology 2022;12:923425
Frontiers in oncology 2022;12:923425
Knockdown of USP8 inhibits prostate cancer cell growth, proliferation, and metastasis and promotes docetaxel's activity by suppressing the NF-kB signaling pathway.
Islam MT, Chen FZ, Chen HC, Wahid A
Frontiers in oncology 2022;12:923270
Frontiers in oncology 2022;12:923270
OCT4 induces EMT and promotes ovarian cancer progression by regulating the PI3K/AKT/mTOR pathway.
Xie W, Yu J, Yin Y, Zhang X, Zheng X, Wang X
Frontiers in oncology 2022;12:876257
Frontiers in oncology 2022;12:876257
Chordin-Like 1 Regulates Epithelial-to-Mesenchymal Transition and Metastasis via the MAPK Signaling Pathway in Oral Squamous Cell Carcinoma.
Wu Q, Zheng Z, Zhang J, Piao Z, Xin M, Xiang X, Wu A, Zhao T, Huang S, Qiao Y, Zhou J, Xu S, Cheng H, Wu L, Ouyang K
Frontiers in oncology 2022;12:862751
Frontiers in oncology 2022;12:862751
Correlation Analysis of Gut Microbiota and Serum Metabolome With Porphyromonas gingivalis-Induced Metabolic Disorders.
Dong Z, Lv W, Zhang C, Chen S
Frontiers in cellular and infection microbiology 2022;12:858902
Frontiers in cellular and infection microbiology 2022;12:858902
Integrated Network Pharmacology and Experimental Verification to Explore the Molecular Mechanism of Hedysarum Multijugum Maxim-Curcumae Rhizoma Herb Pair for Treating Non-Small Cell Lung Cancer.
Hu S, Ge M, Zhang S, Jiang M, Hu K, Gao L
Frontiers in oncology 2022;12:854596
Frontiers in oncology 2022;12:854596
Agonists Specific for κ-Opioid Receptor Induces Apoptosis of HCC Cells Through Enhanced Endoplasmic Reticulum Stress.
Tan M, Wang H, Gao C, Jiang Z, Yin Y, Xing R, Hu L, Xu J, Zhang M, Xie Y
Frontiers in oncology 2022;12:844214
Frontiers in oncology 2022;12:844214
Up-Regulated MISP Is Associated With Poor Prognosis and Immune Infiltration in Pancreatic Ductal Adenocarcinoma.
Huang X, Zhao L, Jin Y, Wang Z, Li T, Xu H, Wang Q, Wang L
Frontiers in oncology 2022;12:827051
Frontiers in oncology 2022;12:827051
ACADL Functions as a Tumor Suppressor in Hepatocellular Carcinoma Metastasis by Inhibiting Matrix Metalloproteinase 14.
Guo D, Zhang X, Cui H, Yu D, Zhang H, Shi X, Pang C, Li J, Guo W, Zhang S
Frontiers in oncology 2022;12:821484
Frontiers in oncology 2022;12:821484
Loss of Frizzled 9 in Lung Cells Alters Epithelial Phenotype and Promotes Premalignant Lesion Development.
Sompel K, Dwyer-Nield LD, Smith AJ, Elango AP, Vanderlinden LA, Kopf K, Keith RL, Tennis MA
Frontiers in oncology 2022;12:815737
Frontiers in oncology 2022;12:815737
NUF2 Expression Promotes Lung Adenocarcinoma Progression and Is Associated With Poor Prognosis.
Jiang F, Huang X, Yang X, Zhou H, Wang Y
Frontiers in oncology 2022;12:795971
Frontiers in oncology 2022;12:795971
Syntenin Regulated by miR-216b Promotes Cancer Progression in Pancreatic Cancer.
Zu F, Chen H, Liu Q, Zang H, Li Z, Tan X
Frontiers in oncology 2022;12:790788
Frontiers in oncology 2022;12:790788
N-Glycosylation at Asn291 Stabilizes TIM-4 and Promotes the Metastasis of NSCLC.
Chen S, Wang Y, Liu W, Liang Y, Wang Y, Wu Z, Xu L, Liang X, Ma C, Gao L
Frontiers in oncology 2022;12:730530
Frontiers in oncology 2022;12:730530
Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta gene as a tumour suppressor in stomach adenocarcinoma.
Li Y, Xiong JB, Jie ZG, Xiong H
Frontiers in oncology 2022;12:1069875
Frontiers in oncology 2022;12:1069875
Prognostic biomarker MCP-4 triggers epithelial-mesenchymal transition via the p38 MAPK pathway in ovarian cancer.
Li S, Hu Y, Liu O, Li X, Lin B
Frontiers in oncology 2022;12:1034737
Frontiers in oncology 2022;12:1034737
Consistent downregulation of the cleft lip/palate-associated genes IRF6 and GRHL3 in carcinomas.
Parisi L, Mockenhaupt C, Rihs S, Mansour F, Katsaros C, Degen M
Frontiers in oncology 2022;12:1023072
Frontiers in oncology 2022;12:1023072
Loss of CMTM6 promotes DNA damage-induced cellular senescence and antitumor immunity.
Wang H, Fan Y, Chen W, Lv Z, Wu S, Xuan Y, Wang C, Lu Y, Guo T, Shen D, Zhang F, Huang Q, Gao Y, Li H, Ma X, Wang B, Huang Y, Zhang X
Oncoimmunology 2022;11(1):2011673
Oncoimmunology 2022;11(1):2011673
A long noncoding RNA GTF2IRD2P1 suppresses cell proliferation in bladder cancer by inhibiting the Wnt/β‑catenin signaling pathway.
Huang Z, Gao H, Qing L, Wang B, He C, Luo N, Lu C, Fan S, Gu P, Zhao H
PeerJ 2022;10:e13220
PeerJ 2022;10:e13220
ATP11A promotes EMT by regulating Numb PRR(L) in pancreatic cancer cells.
Chen L, Tang J, Sheng W, Sun J, Ma Y, Dong M
PeerJ 2022;10:e13172
PeerJ 2022;10:e13172
CircFGGY Inhibits Cell Growth, Invasion and Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma via Regulating the miR-545-3p/Smad7 Axis.
Feng KL, Diao N, Zhou ZW, Fang CK, Wang JN, Zhang Y, Luo R, Zhong C
Frontiers in cell and developmental biology 2022;10:850708
Frontiers in cell and developmental biology 2022;10:850708
Targeting MALT1 Suppresses the Malignant Progression of Colorectal Cancer via miR-375/miR-365a-3p/NF-κB Axis.
Qian R, Niu X, Wang Y, Guo Z, Deng X, Ding Z, Zhou M, Deng H
Frontiers in cell and developmental biology 2022;10:845048
Frontiers in cell and developmental biology 2022;10:845048
TAGLN2-Regulated Trophoblast Migration, Invasion and Fusion are Impaired in Preeclampsia.
Wang H, Zhang X, Liu C, Chen S, Liu X, Fan S
Frontiers in cell and developmental biology 2022;10:810633
Frontiers in cell and developmental biology 2022;10:810633
Heat stress and hypoxia inhibit the secretion of androgens and induce epithelial-to-mesenchymal transition associated with activated TGF-β/Smad signalling in canine cryptorchidism.
Wang Z, Wang Q, Cui N, Xiao L, Wei H, Kang J, Sheng X, Qi X, Xing K, Guo Y, Ni H, Wang X
Reproduction in domestic animals = Zuchthygiene 2022 Sep;57(9):1046-1055
Reproduction in domestic animals = Zuchthygiene 2022 Sep;57(9):1046-1055
GTSE1 promotes tumor growth and metastasis by attenuating of KLF4 expression in clear cell renal cell carcinoma.
Chen W, Wang H, Lu Y, Huang Y, Xuan Y, Li X, Guo T, Wang C, Lai D, Wu S, Zhao W, Mai H, Li H, Wang B, Ma X, Zhang X
Laboratory investigation; a journal of technical methods and pathology 2022 Sep;102(9):1011-1022
Laboratory investigation; a journal of technical methods and pathology 2022 Sep;102(9):1011-1022
Glutamine in suppression of lipopolysaccharide-induced piglet intestinal inflammation: The crosstalk between AMPK activation and mitochondrial function.
He L, Zhou X, Wu Z, Feng Y, Liu D, Li T, Yin Y
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Sep;10:137-147
Animal nutrition (Zhongguo xu mu shou yi xue hui) 2022 Sep;10:137-147
Discovery and characterization of heterogeneous and multipotent fibroblast populations isolated from excised cleft lip tissue.
Parisi L, Rihs S, La Scala GC, Schnyder I, Katsaros C, Degen M
Stem cell research & therapy 2022 Sep 8;13(1):469
Stem cell research & therapy 2022 Sep 8;13(1):469
Histone methyltransferase MLL1 drives renal tubular cell apoptosis by p53-dependent repression of E-cadherin during cisplatin-induced acute kidney injury.
Zhang C, Guan Y, Zou J, Yang X, Bayliss G, Zhuang S
Cell death & disease 2022 Sep 6;13(9):770
Cell death & disease 2022 Sep 6;13(9):770
TRAF4 Promotes the Proliferation of Glioblastoma by Stabilizing SETDB1 to Activate the AKT Pathway.
Gu H, Zhu S, Peng C, Wei Z, Shen Y, Yuan C, Yang H, Cui H, Yang L
International journal of molecular sciences 2022 Sep 5;23(17)
International journal of molecular sciences 2022 Sep 5;23(17)
MICAL2 contributes to gastric cancer cell migration via Cdc42-dependent activation of E-cadherin/β-catenin signaling pathway.
Wang Q, Qi C, Min P, Wang Y, Ye F, Xia T, Zhang Y, Du J
Cell communication and signaling : CCS 2022 Sep 5;20(1):136
Cell communication and signaling : CCS 2022 Sep 5;20(1):136
MicroRNA-20a-5p regulates the epithelial-mesenchymal transition of human hepatocellular carcinoma by targeting RUNX3.
Wang X, Wei P, Yang L, Liu F, Tong X, Yang X, Su L
Chinese medical journal 2022 Sep 5;135(17):2089-2097
Chinese medical journal 2022 Sep 5;135(17):2089-2097
TFAP2C Knockdown Sensitizes Bladder Cancer Cells to Cisplatin Treatment via Regulation of EGFR and NF-κB.
Xing J, Chen W, Chen K, Zhu S, Lin F, Qi Y, Zhang Y, Han S, Rao T, Ruan Y, Zhao S, Yu W, Cheng F
Cancers 2022 Sep 30;14(19)
Cancers 2022 Sep 30;14(19)
Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.
Jin S, He X, Ma L, Zhuang Z, Wang Y, Lin M, Cai S, Wei L, Wang Z, Zhao Z, Wu Y, Sun L, Li C, Xie W, Zhao Y, Songyang Z, Peng K, Zhao J, Cui J
Nature communications 2022 Sep 3;13(1):5204
Nature communications 2022 Sep 3;13(1):5204
Exosomal miR-22-3p from Mesenchymal Stem Cells Inhibits the Epithelial-Mesenchymal Transition (EMT) of Melanoma Cells by Regulating LGALS1.
Chen Y, Fang Y, Li L, Luo H, Cao T, Tu B
Frontiers in bioscience (Landmark edition) 2022 Sep 29;27(9):275
Frontiers in bioscience (Landmark edition) 2022 Sep 29;27(9):275
BMP2 promotes lung adenocarcinoma metastasis through BMP receptor 2-mediated SMAD1/5 activation.
Wu CK, Wei MT, Wu HC, Wu CL, Wu CJ, Liaw H, Su WP
Scientific reports 2022 Sep 29;12(1):16310
Scientific reports 2022 Sep 29;12(1):16310
HOXA5 inhibits the proliferation of extrahepatic cholangiocarcinoma cells by enhancing MXD1 expression and activating the p53 pathway.
Xiong F, Liu W, Wang X, Wu G, Wang Q, Guo T, Huang W, Wang B, Chen Y
Cell death & disease 2022 Sep 27;13(9):829
Cell death & disease 2022 Sep 27;13(9):829
NR2F1 Regulates TGF-β1-Mediated Epithelial-Mesenchymal Transition Affecting Platinum Sensitivity and Immune Response in Ovarian Cancer.
Liang Q, Xu Z, Liu Y, Peng B, Cai Y, Liu W, Yan Y
Cancers 2022 Sep 24;14(19)
Cancers 2022 Sep 24;14(19)
Taraxasterol Inhibits Tumor Growth by Inducing Apoptosis and Modulating the Tumor Microenvironment in Non-Small Cell Lung Cancer.
Lu J, Shuai B, Shou Z, Guo W, Zhou C, Ouyang X, Zhou H, Li J, Cui J, Jiang F, Jin KY, Sarapultsev A, Li F, Zhang G, Luo S, Hu D
Cancers 2022 Sep 24;14(19)
Cancers 2022 Sep 24;14(19)
AHSA1 Promotes Proliferation and EMT by Regulating ERK/CALD1 Axis in Hepatocellular Carcinoma.
Zhang J, Ren Z, Zheng D, Song Z, Lin J, Luo Y, Zou X, Pan Y, Qi N, Li A, Liu X
Cancers 2022 Sep 22;14(19)
Cancers 2022 Sep 22;14(19)
Genistein Restricts the Epithelial Mesenchymal Transformation (EMT) and Stemness of Hepatocellular Carcinoma via Upregulating miR-1275 to Inhibit the EIF5A2/PI3K/Akt Pathway.
Yang X, Jiang W, Kong X, Zhou X, Zhu D, Kong L
Biology 2022 Sep 22;11(10)
Biology 2022 Sep 22;11(10)
KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.
Yao H, Ren D, Wang Y, Wu L, Wu Y, Wang W, Li Q, Liu L
Cell death & disease 2022 Sep 2;13(9):761
Cell death & disease 2022 Sep 2;13(9):761
CAV2 promotes the invasion and metastasis of head and neck squamous cell carcinomas by regulating S100 proteins.
Wang Y, Wang Y, Liu R, Wang C, Luo Y, Chen L, He Y, Zhu K, Guo H, Zhang Z, Luo J
Cell death discovery 2022 Sep 16;8(1):386
Cell death discovery 2022 Sep 16;8(1):386
Inhibition of PTPN21 has antitumor effects in glioma by restraining the EGFR/PI3K/AKT pathway.
Li XQ, Liu BC, Jiang XB, Gao WW, Rong B, Wei Y, Wang FL, Zhao HK, Zhang L
Toxicology and applied pharmacology 2022 Sep 15;451:116180
Toxicology and applied pharmacology 2022 Sep 15;451:116180
Upregulation of miR-520c-3p via hepatitis B virus drives hepatocellular migration and invasion by the PTEN/AKT/NF-κB axis.
Liu Y, Wang J, Chen J, Wu S, Zeng X, Xiong Q, Guo Y, Sun J, Song F, Xu J, Yuan S, Li C, He Y, Wang M, Chen L, Shi YB, Guo M, Guo D, Sun G
Molecular therapy. Nucleic acids 2022 Sep 13;29:47-63
Molecular therapy. Nucleic acids 2022 Sep 13;29:47-63
Hypoxia-induced polarization of M2 macrophages and C-C motif chemokine ligand 5 secretion promotes the migration and invasion of trophoblasts†.
Chen X, Song QL, Ji R, Wang JY, Li ZH, Xiao ZN, Guo DY, Yang J
Biology of reproduction 2022 Sep 12;107(3):834-845
Biology of reproduction 2022 Sep 12;107(3):834-845
EP300 promotes renal tubular epithelial cell fibrosis by increasing HIF2α expression in diabetic nephropathy.
Gong Y, Dou Y, Wang L, Wang X, Zhao Z
Cellular signalling 2022 Oct;98:110407
Cellular signalling 2022 Oct;98:110407
Anti-inflammatory potential of stevia residue extract against uric acid-associated renal injury in mice.
Mehmood A, Althobaiti F, Zhao L, Usman M, Chen X, Alharthi F, Soliman MM, Shah AA, Murtaza MA, Nadeem M, Ranjha MMAN, Wang C
Journal of food biochemistry 2022 Oct;46(10):e14286
Journal of food biochemistry 2022 Oct;46(10):e14286
PLEK2 promotes cancer stemness and tumorigenesis of head and neck squamous cell carcinoma via the c-Myc-mediated positive feedback loop.
Zhao X, Shu D, Sun W, Si S, Ran W, Guo B, Cui L
Cancer communications (London, England) 2022 Oct;42(10):987-1007
Cancer communications (London, England) 2022 Oct;42(10):987-1007
Exosomes derived from mesenchymal stem cells attenuate diabetic kidney disease by inhibiting cell apoptosis and epithelial-to-mesenchymal transition via miR-424-5p.
Cui C, Zang N, Song J, Guo X, He Q, Hu H, Yang M, Wang Y, Yang J, Zou Y, Gao J, Wang L, Wang C, Liu F, He F, Hou X, Chen L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Oct;36(10):e22517
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Oct;36(10):e22517
Bryodulcosigenin attenuates bleomycin-induced pulmonary fibrosis via inhibiting AMPK-mediated mesenchymal epithelial transition and oxidative stress.
Ding Y, Wang L, Liu B, Ren G, Okubo R, Yu J, Zhang C
Phytotherapy research : PTR 2022 Oct;36(10):3911-3923
Phytotherapy research : PTR 2022 Oct;36(10):3911-3923
Transcription factor YY1 contributes to human melanoma cell growth through modulating the p53 signalling pathway.
Zhou S, Li P, Qin L, Huang S, Dang N
Experimental dermatology 2022 Oct;31(10):1563-1578
Experimental dermatology 2022 Oct;31(10):1563-1578
Upregulation of Wilms' Tumor 1 in epicardial cells increases cardiac fibrosis in dystrophic mice.
Guo Z, Geng M, Huang Y, Han G, Jing R, Lin C, Zhang X, Zhang M, Fan G, Wang F, Yin H
Cell death and differentiation 2022 Oct;29(10):1928-1940
Cell death and differentiation 2022 Oct;29(10):1928-1940
Identification of a five m6A-relevant mRNAs signature and risk score for the prognostication of gastric cancer.
Yin L, Feng S, Sun Y, Jiang Y, Tang C, Sun D
Journal of gastrointestinal oncology 2022 Oct;13(5):2234-2248
Journal of gastrointestinal oncology 2022 Oct;13(5):2234-2248
LHX2 facilitates the progression of nasopharyngeal carcinoma via activation of the FGF1/FGFR axis.
Xie T, Du K, Liu W, Liu C, Wang B, Tian Y, Li R, Huang X, Lin J, Jian H, Zhang J, Yuan Y
British journal of cancer 2022 Oct;127(7):1239-1253
British journal of cancer 2022 Oct;127(7):1239-1253
Tumor-associated macrophages promote migration and invasion via modulating IL-6/STAT3 signaling in renal cell carcinoma.
Chen S, Qian S, Zhang L, Pan X, Qu F, Yu Y, Gu Z, Cui X, Shen H
International immunopharmacology 2022 Oct;111:109139
International immunopharmacology 2022 Oct;111:109139
Natural shikonin and acetyl-shikonin improve intestinal microbial and protein composition to alleviate colitis-associated colorectal cancer.
Lin H, Ma X, Yang X, Chen Q, Wen Z, Yang M, Fu J, Yin T, Lu G, Qi J, Han H, Yang Y
International immunopharmacology 2022 Oct;111:109097
International immunopharmacology 2022 Oct;111:109097
Downregulation of exosomal miR-7-5p promotes breast cancer migration and invasion by targeting RYK and participating in the atypical WNT signalling pathway.
Liang Z, Liu L, Gao R, Che C, Yang G
Cellular & molecular biology letters 2022 Oct 9;27(1):88
Cellular & molecular biology letters 2022 Oct 9;27(1):88
Tension of plus-end tracking protein Clip170 confers directionality and aggressiveness during breast cancer migration.
Hu Y, Xie Q, Wu X, Liu W, Li D, Li C, Zhao W, Chen L, Zheng Z, Li G, Guo J
Cell death & disease 2022 Oct 8;13(10):856
Cell death & disease 2022 Oct 8;13(10):856
ALG3 Promotes Peritoneal Metastasis of Ovarian Cancer through Increasing Interaction of α1,3-mannosylated uPAR and ADAM8.
Cui X, Pei X, Wang H, Feng P, Qin H, Liu S, Yan Q, Liu J
Cells 2022 Oct 6;11(19)
Cells 2022 Oct 6;11(19)
LPAR5 confers radioresistance to cancer cells associated with EMT activation via the ERK/Snail pathway.
Sun XY, Li HZ, Xie DF, Gao SS, Huang X, Guan H, Bai CJ, Zhou PK
Journal of translational medicine 2022 Oct 5;20(1):456
Journal of translational medicine 2022 Oct 5;20(1):456
Local Application of Krill Oil Accelerates the Healing of Artificially Created Wounds in Diabetic Mice.
Hao W, Meng H, Li H, Zheng Y, Song C, Jiang Z, Bai X, Zhang Z, Du L, Liu P, Wu H
Nutrients 2022 Oct 5;14(19)
Nutrients 2022 Oct 5;14(19)
LMNA Reduced Acquired Resistance to Erlotinib in NSCLC by Reversing the Epithelial-Mesenchymal Transition via the FGFR/MAPK/c-fos Signaling Pathway.
Hu C, Zhou A, Hu X, Xiang Y, Huang M, Huang J, Yang D, Tang Y
International journal of molecular sciences 2022 Oct 31;23(21)
International journal of molecular sciences 2022 Oct 31;23(21)
IGF2BP2 Promotes Epithelial to Mesenchymal Transition and Metastasis through Stabilizing HMGA1 mRNA in Gastric Cancer.
Ouyang J, Li J, Li D, Jiang J, Hao T, Xia Y, Lu X, Zhang C, He Y
Cancers 2022 Oct 31;14(21)
Cancers 2022 Oct 31;14(21)
Fucoxanthin induces apoptosis and reverses epithelial-mesenchymal transition via inhibiting Wnt/β-catenin pathway in lung adenocarcinoma.
Luan H, Yan L, Zhao Y, Ding X, Cao L
Discover oncology 2022 Oct 3;13(1):98
Discover oncology 2022 Oct 3;13(1):98
MICALL2 as a substrate of ubiquitinase TRIM21 regulates tumorigenesis of colorectal cancer.
Wen P, Wang H, Li Y, Sui X, Hou Z, Guo X, Xue W, Liu D, Wang Y, Gao J
Cell communication and signaling : CCS 2022 Oct 28;20(1):170
Cell communication and signaling : CCS 2022 Oct 28;20(1):170
FTO Inhibits Epithelial Ovarian Cancer Progression by Destabilising SNAI1 mRNA through IGF2BP2.
Sun M, Zhang X, Bi F, Wang D, Zhou X, Li X, Yang Q
Cancers 2022 Oct 25;14(21)
Cancers 2022 Oct 25;14(21)
Downregulation of TUSC3 promotes EMT and hepatocellular carcinoma progression through LIPC/AKT axis.
Deng R, Lu X, Hong C, Cai R, Wang P, Xiong L, Wang X, Chen Q, Lin J
Journal of translational medicine 2022 Oct 23;20(1):485
Journal of translational medicine 2022 Oct 23;20(1):485
CAMK2N1 has a cancer-suppressive function in colorectal carcinoma via effects on the Wnt/β-catenin pathway.
Zhang X, Tian L, Li Z, Liu R, Yu J, Liu B
Biochemical and biophysical research communications 2022 Oct 20;626:220-228
Biochemical and biophysical research communications 2022 Oct 20;626:220-228
Isolation, purification and characterization of Pueraria lobata polysaccharide and its effects on intestinal function in cyclophosphamide-treated mice.
Cai G, Wu C, Mao N, Song Z, Yu L, Zhu T, Peng S, Yang Y, Liu Z, Wang D
International journal of biological macromolecules 2022 Oct 1;218:356-367
International journal of biological macromolecules 2022 Oct 1;218:356-367
Role of non-neuronal cholinergic system in the early stage response of epithelial-mesenchymal transformation related markers in A549 cells induced by coal particles.
Wu MY, Shi XC, Shan J, Wang R, Wang Y, Li J, Tian DN, Xu HM
Heliyon 2022 Nov;8(11):e11751
Heliyon 2022 Nov;8(11):e11751
Knockdown of TTC9 inhibits the proliferation, migration and invasion, but induces the apoptosis of lung adenocarcinoma cells.
Huang X, Jiang L, Wen Z, Yuan M, Zhong Y
Heliyon 2022 Nov;8(11):e11254
Heliyon 2022 Nov;8(11):e11254
Acyl-CoA thioesterase 9 promotes tumour growth and metastasis through reprogramming of fatty acid metabolism in hepatocellular carcinoma.
Wang B, Zhang H, Chen YF, Hu LQ, Tian YY, Tong HW, Wang G, Chen C, Yuan P
Liver international : official journal of the International Association for the Study of the Liver 2022 Nov;42(11):2548-2561
Liver international : official journal of the International Association for the Study of the Liver 2022 Nov;42(11):2548-2561
Targeting epiregulin in the treatment-damaged tumor microenvironment restrains therapeutic resistance.
Wang C, Long Q, Fu Q, Xu Q, Fu D, Li Y, Gao L, Guo J, Zhang X, Lam EW, Campisi J, Sun Y
Oncogene 2022 Nov;41(45):4941-4959
Oncogene 2022 Nov;41(45):4941-4959
Endophilin A2 protects against renal fibrosis by targeting TGF-β/Smad signaling.
Mai X, Shang J, Chen Q, Gu S, Hong Y, Zhou J, Zhang M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Nov;36(11):e22603
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Nov;36(11):e22603
Metabolomic Analysis Reveals that SPHK1 Promotes Oral Squamous Cell Carcinoma Progression through NF-κB Activation.
Hou CX, Mao GY, Sun QW, Meng Y, Zhu QH, Tang YT, Han W, Sun NN, Song XM, Wang CX, Ye JH
Annals of surgical oncology 2022 Nov;29(12):7386-7399
Annals of surgical oncology 2022 Nov;29(12):7386-7399
Legumain affects the PI3K/AKT tumor progression pathway in retinoblastoma.
Tang Q, Xu F, Lin J, Zhang C, Liu X, Dong L, Zhao J, Zhu L, Lin T
Experimental eye research 2022 Nov;224:109221
Experimental eye research 2022 Nov;224:109221
MYPT1 inhibits the metastasis of renal clear cell carcinoma via the MAPK8/N-cadherin pathway.
Xie Q, Liu R, Zou Z, Feng Y, Huang Y, Xu G, Sun W, Liang Y, Zhong W
FEBS open bio 2022 Nov;12(11):2083-2095
FEBS open bio 2022 Nov;12(11):2083-2095
Knockdown of SOX9 alleviates tracheal fibrosis through the Wnt/β-catenin signaling pathway.
Gu L, Li A, Lin J, Gan Y, He C, Xiao R, Liao J, Li Y, Guo S
Journal of molecular medicine (Berlin, Germany) 2022 Nov;100(11):1659-1670
Journal of molecular medicine (Berlin, Germany) 2022 Nov;100(11):1659-1670
SIRT2 promotes the viability, invasion and metastasis of osteosarcoma cells by inhibiting the degradation of Snail.
Tian Y, Liu R, Hou X, Gao Z, Liu X, Zhang W
Cell death & disease 2022 Nov 7;13(11):935
Cell death & disease 2022 Nov 7;13(11):935
MK-2206 Alleviates Renal Fibrosis by Suppressing the Akt/mTOR Signaling Pathway In Vivo and In Vitro.
Chen M, Yu Y, Mi T, Guo Q, Xiang B, Tian X, Jin L, Long C, Shen L, Liu X, Pan J, Zhang Y, Xu T, Zhang D, Wei G
Cells 2022 Nov 5;11(21)
Cells 2022 Nov 5;11(21)
Follistatin Is a Novel Chemoattractant for Migration and Invasion of Placental Trophoblasts of Mice.
Li J, Qi Y, Yang K, Zhu L, Cui X, Liu Z
Cells 2022 Nov 29;11(23)
Cells 2022 Nov 29;11(23)
Ovarian tumorB1-mediated heat shock transcription factor 1 deubiquitination is critical for glycolysis and development of endometriosis.
Ling X, Lu J, Wang X, Liu L, Liu L, Wang Y, Sun Y, Ren C, Lu C, Yu Z
iScience 2022 Nov 18;25(11):105363
iScience 2022 Nov 18;25(11):105363
METTL1 drives tumor progression of bladder cancer via degrading ATF3 mRNA in an m(7)G-modified miR-760-dependent manner.
Xie H, Wang M, Yu H, Wang H, Ding L, Wang R, Luo W, Lu Z, Zheng Q, Ren L, Zhou Z, Su W, Xia L, Li G
Cell death discovery 2022 Nov 17;8(1):458
Cell death discovery 2022 Nov 17;8(1):458
Palmitic Acid Promotes Lung Metastasis of Melanomas via the TLR4/TRIF-Peli1-pNF-κB Pathway.
Zhang X, Li X, Xiong G, Yun F, Feng Y, Ni Q, Wu N, Yang L, Yi Z, Zhang Q, Yang Z, Kuang Y, Sai B, Zhu Y
Metabolites 2022 Nov 17;12(11)
Metabolites 2022 Nov 17;12(11)
FGF2 isoforms play distinct roles in tubular epithelial-to-mesenchymal transition in diabetic nephropathy.
Luo Y, Deng D, Lin L, Zhou Y, Wang L, Zou X, Wang X
Experimental cell research 2022 Nov 15;420(2):113355
Experimental cell research 2022 Nov 15;420(2):113355
Design and biological features of platinum (II) complexes with 3-hydroxy-3-(Trifluoromethyl)cyclobutane-1,1-Dicarboxylate as a leaving ligand.
Liu F, Yang C, Li S, Wu X, Xue K, Zhou Y, Liang X, Cheng X, Shi Q, Su W
European journal of medicinal chemistry 2022 Nov 15;242:114673
European journal of medicinal chemistry 2022 Nov 15;242:114673
MiR-30e-3p inhibits gastric cancer development by negatively regulating THO complex 2 and PI3K/AKT/mTOR signaling.
Gu XJ, Li YJ, Wang F, Ye T
World journal of gastrointestinal oncology 2022 Nov 15;14(11):2170-2182
World journal of gastrointestinal oncology 2022 Nov 15;14(11):2170-2182
N-glycosylation of CD82 at Asn157 is required for suppressing migration and invasion by reversing EMT via Wnt/β-catenin pathway in colon cancer.
Zhu L, Chen Y, Du H, Cong Y, Yan W, Ma K, Huang X
Biochemical and biophysical research communications 2022 Nov 12;629:121-127
Biochemical and biophysical research communications 2022 Nov 12;629:121-127
NAP1L5 targeting combined with MYH9 Inhibit HCC progression through PI3K/AKT/mTOR signaling pathway.
Zhao R, Ge Y, Gong Y, Li B, Xiao B, Zuo S
Aging 2022 Nov 11;14(22):9000-9019
Aging 2022 Nov 11;14(22):9000-9019
Circular RNA hsa_circ_0051040 Promotes Hepatocellular Carcinoma Progression by Sponging miR-569 and Regulating ITGAV Expression.
Ju L, Yao M, Lu R, Cao Y, Wang H, Yuan L, Xiao F, Shao J, Cai W, Chen L, Bian Z
Cells 2022 Nov 11;11(22)
Cells 2022 Nov 11;11(22)
Cancer-associated fibroblasts promote the stemness and progression of renal cell carcinoma via exosomal miR-181d-5p.
Ding M, Zhao X, Chen X, Diao W, Kan Y, Cao W, Chen W, Jiang B, Qin H, Gao J, Zhuang J, Zhang Q, Guo H
Cell death discovery 2022 Nov 1;8(1):439
Cell death discovery 2022 Nov 1;8(1):439
KIF17 maintains the epithelial phenotype of breast cancer cells and curbs tumour metastasis.
Li T, Zhai D, Zhang M, Ye R, Kuang X, Shao N, Bi J, Lin Y
Cancer letters 2022 Nov 1;548:215904
Cancer letters 2022 Nov 1;548:215904
The inhibition of centromere protein K causes anticancer effects in breast carcinoma via effects on the FAK/PI3K/AKT/mTOR pathway.
Yu J, Wang K, Yang S, Li G
Toxicology and applied pharmacology 2022 Nov 1;454:116232
Toxicology and applied pharmacology 2022 Nov 1;454:116232
Sinapic acid inhibits pancreatic cancer proliferation, migration, and invasion via downregulation of the AKT/Gsk-3β signal pathway.
Huang Z, Chen H, Tan P, Huang M, Shi H, Sun B, Cheng Y, Li T, Mou Z, Li Q, Fu W
Drug development research 2022 May;83(3):721-734
Drug development research 2022 May;83(3):721-734
Development of Clinical-Grade Antibodies against Tumor-Specific Mutations to Target Neuroblastoma.
Pero SC, Nagulapally AB, Mei L, Zhang F, Sholler GS, Krag DN, Shukla GS
Annals of clinical and laboratory science 2022 May;52(3):349-358
Annals of clinical and laboratory science 2022 May;52(3):349-358
RhoGDI2 induced malignant phenotypes of pancreatic cancer cells via regulating Snail expression.
Yi B, Hu Y, Zhu D, Yao J, Zhou J, Zhang Y, He Z, Zhang L, Zhang Z, Yang J, Tang Y, Huang Y, Li D, Liu Q
Genes & genomics 2022 May;44(5):561-569
Genes & genomics 2022 May;44(5):561-569
miR-217-5p suppresses epithelial-mesenchymal transition and the NF-κB signaling pathway in breast cancer via targeting of metadherin.
Yang L, Liu S, Yang L, Xu B, Wang M, Kong X, Song Z
Oncology letters 2022 May;23(5):162
Oncology letters 2022 May;23(5):162
Exosomal MMP-1 transfers metastasis potential in triple-negative breast cancer through PAR1-mediated EMT.
Zhu Y, Tao Z, Chen Y, Lin S, Zhu M, Ji W, Liu X, Li T, Hu X
Breast cancer research and treatment 2022 May;193(1):65-81
Breast cancer research and treatment 2022 May;193(1):65-81
Kinesin family member 23, regulated by FOXM1, promotes triple negative breast cancer progression via activating Wnt/β-catenin pathway.
Li Z, Yang HY, Zhang XL, Zhang X, Huang YZ, Dai XY, Shi L, Zhou GR, Wei JF, Ding Q
Journal of experimental & clinical cancer research : CR 2022 May 7;41(1):168
Journal of experimental & clinical cancer research : CR 2022 May 7;41(1):168
Forkhead Box q1 promotes invasion and metastasis in colorectal cancer by activating the epidermal growth factor receptor pathway.
Zhang JJ, Cao CX, Wan LL, Zhang W, Liu ZJ, Wang JL, Guo Q, Tang H
World journal of gastroenterology 2022 May 7;28(17):1781-1797
World journal of gastroenterology 2022 May 7;28(17):1781-1797
FAM126A interacted with ENO1 mediates proliferation and metastasis in pancreatic cancer via PI3K/AKT signaling pathway.
Li Y, Li Y, Luo J, Fu X, Liu P, Liu S, Pan Y
Cell death discovery 2022 May 5;8(1):248
Cell death discovery 2022 May 5;8(1):248
Spatiotemporal Gene Expression Regions along the Anterior-Posterior Axis in Mouse Embryos before and after Palatal Elevation.
Nagasaka A, Sakiyama K, Bando Y, Yamamoto M, Abe S, Amano O
International journal of molecular sciences 2022 May 5;23(9)
International journal of molecular sciences 2022 May 5;23(9)
Multinucleated Retinal Pigment Epithelial Cells Adapt to Vision and Exhibit Increased DNA Damage Response.
Ke Q, Gong L, Zhu X, Qi R, Zou M, Chen B, Liu W, Huang S, Liu Y, Li DW
Cells 2022 May 5;11(9)
Cells 2022 May 5;11(9)
FAT10 promotes chemotherapeutic resistance in pancreatic cancer by inducing epithelial-mesenchymal transition via stabilization of FOXM1 expression.
Zhu J, Zhao J, Luo C, Zhu Z, Peng X, Zhu X, Lin K, Bu F, Zhang W, Li Q, Wang K, Hu Z, Yu X, Chen L, Yuan R
Cell death & disease 2022 May 25;13(5):497
Cell death & disease 2022 May 25;13(5):497
Targeting dual-specificity tyrosine phosphorylation-regulated kinase 2 with a highly selective inhibitor for the treatment of prostate cancer.
Yuan K, Li Z, Kuang W, Wang X, Ji M, Chen W, Ding J, Li J, Min W, Sun C, Ye X, Lu M, Wang L, Ge H, Jiang Y, Hao H, Xiao Y, Yang P
Nature communications 2022 May 25;13(1):2903
Nature communications 2022 May 25;13(1):2903
MiR-135a-5p suppresses trophoblast proliferative, migratory, invasive, and angiogenic activity in the context of unexplained spontaneous abortion.
Lu Y, Zhang X, Li X, Deng L, Wei C, Yang D, Tan X, Pan W, Pang L
Reproductive biology and endocrinology : RB&E 2022 May 24;20(1):82
Reproductive biology and endocrinology : RB&E 2022 May 24;20(1):82
Therapeutic Effect of Platelet-Rich Plasma Improves Bladder Overactivity in the Pathogenesis of Ketamine-Induced Ulcerative Cystitis in a Rat Model.
Chueh KS, Huang KH, Lu JH, Juan TJ, Chuang SM, Lin RJ, Lee YC, Long CY, Shen MC, Sun TW, Juan YS
International journal of molecular sciences 2022 May 21;23(10)
International journal of molecular sciences 2022 May 21;23(10)
[P4HA2 promotes occurrence and progression of liver cancer by regulating the PI3K/Akt/mTOR signaling pathway].
Shang L, Jiang W, Zhang J, Wu W
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2022 May 20;42(5):665-672
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2022 May 20;42(5):665-672
A comprehensive analysis of potential gastric cancer prognostic biomarker ITGBL1 associated with immune infiltration and epithelial-mesenchymal transition.
Wang Z, Fu L, Zhang J, Ge Y, Guo C, Wang R, Deng M, Wang Q, Wang Z
Biomedical engineering online 2022 May 20;21(1):30
Biomedical engineering online 2022 May 20;21(1):30
Cancer associated fibroblast-derived CCL5 promotes hepatocellular carcinoma metastasis through activating HIF1α/ZEB1 axis.
Xu H, Zhao J, Li J, Zhu Z, Cui Z, Liu R, Lu R, Yao Z, Xu Q
Cell death & disease 2022 May 20;13(5):478
Cell death & disease 2022 May 20;13(5):478
Construction of gastric cancer patient-derived organoids and their utilization in a comparative study of clinically used paclitaxel nanoformulations.
Zou J, Wang S, Chai N, Yue H, Ye P, Guo P, Li F, Wei B, Ma G, Wei W, Linghu E
Journal of nanobiotechnology 2022 May 18;20(1):233
Journal of nanobiotechnology 2022 May 18;20(1):233
TMCO1 expression promotes cell proliferation and induces epithelial-mesenchymal transformation in human gliomas.
Gao L, Ye Z, Liu JH, Yang JA, Li Y, Cai JY, Wang YX, Tong SA, Deng G, Zhang S, Chen QX
Medical oncology (Northwood, London, England) 2022 May 15;39(5):90
Medical oncology (Northwood, London, England) 2022 May 15;39(5):90
CXCL13 as a Novel Immune Checkpoint for Regulatory B Cells and Its Role in Tumor Metastasis.
Ren J, Lan T, Liu T, Liu Y, Shao B, Men K, Ma Y, Liang X, Wei YQ, Luo M, Wei XW
Journal of immunology (Baltimore, Md. : 1950) 2022 May 15;208(10):2425-2435
Journal of immunology (Baltimore, Md. : 1950) 2022 May 15;208(10):2425-2435
The enhancer RNA ADCY10P1 is associated with the progression of ovarian cancer.
Mo J, Zhang L, Li H, Duan H, Wang D, Zhao X, Xie Y
Journal of ovarian research 2022 May 14;15(1):61
Journal of ovarian research 2022 May 14;15(1):61
VCP interaction with HMGB1 promotes hepatocellular carcinoma progression by activating the PI3K/AKT/mTOR pathway.
Pu Z, Duda DG, Zhu Y, Pei S, Wang X, Huang Y, Yi P, Huang Z, Peng F, Hu X, Fan X
Journal of translational medicine 2022 May 13;20(1):212
Journal of translational medicine 2022 May 13;20(1):212
Stanniocalcin2 inhibits the epithelial-mesenchymal transition and invasion of trophoblasts via activation of autophagy under high-glucose conditions.
Lai R, Ji L, Zhang X, Xu Y, Zhong Y, Chen L, Hu H, Wang L
Molecular and cellular endocrinology 2022 May 1;547:111598
Molecular and cellular endocrinology 2022 May 1;547:111598
Downregulated RRS1 inhibits invasion and metastasis of BT549 through RPL11‑c‑Myc‑SNAIL axis.
Wang R, Peng C, Song J, Hua Y, Wu Q, Deng L, Cao Y, Zhang J, Zhang L, Wu L, Hou L
International journal of oncology 2022 Mar;60(3)
International journal of oncology 2022 Mar;60(3)
LACTB suppresses carcinogenesis in lung cancer and regulates the EMT pathway.
Xu Y, Shi H, Wang M, Huang P, Xu M, Han S, Li H, Wang Y
Experimental and therapeutic medicine 2022 Mar;23(3):247
Experimental and therapeutic medicine 2022 Mar;23(3):247
Selenium Deficiency Leads to Changes in Renal Fibrosis Marker Proteins and Wnt/β-Catenin Signaling Pathway Components.
Lin T, Tao J, Chen Y, Zhang Y, Li F, Zhang Y, Han X, Zhao Z, Liu G, Li H
Biological trace element research 2022 Mar;200(3):1127-1139
Biological trace element research 2022 Mar;200(3):1127-1139
In situ injectable hydrogel-loaded drugs induce anti-tumor immune responses in melanoma immunochemotherapy.
Li J, Luo G, Zhang C, Long S, Guo L, Yang G, Wang F, Zhang L, Shi L, Fu Y, Zhang Y
Materials today. Bio 2022 Mar;14:100238
Materials today. Bio 2022 Mar;14:100238
LINC00244 suppresses cell growth and metastasis in hepatocellular carcinoma by downregulating programmed cell death ligand 1.
Sun Z, Xue C, Li J, Zhao H, Du Y, Du N
Bioengineered 2022 Mar;13(3):7635-7647
Bioengineered 2022 Mar;13(3):7635-7647
Inhibition of translocator protein 18 kDa suppressed the progression of glioma via the ELAV-like RNA-binding protein 1/MAPK-activated protein kinase 3 axis.
Wang J, Ren P, Zeng Z, Ma L, Li Y, Zhang H, Guo W
Bioengineered 2022 Mar;13(3):7457-7470
Bioengineered 2022 Mar;13(3):7457-7470
YB1 associates with oncogenetic roles and poor prognosis in nasopharyngeal carcinoma.
Zhan Y, Chen X, Zheng H, Luo J, Yang Y, Ning Y, Wang H, Zhang Y, Zhou M, Wang W, Fan S
Scientific reports 2022 Mar 8;12(1):3699
Scientific reports 2022 Mar 8;12(1):3699
The miR-345-3p/PPP2CA signaling axis promotes proliferation and invasion of breast cancer cells.
Zeng Q, Jin F, Qian H, Chen H, Wang Y, Zhang D, Wei Y, Chen T, Guo B, Chai C
Carcinogenesis 2022 Mar 24;43(2):150-159
Carcinogenesis 2022 Mar 24;43(2):150-159
CircESRP1 enhances metastasis and epithelial-mesenchymal transition in endometrial cancer via the miR-874-3p/CPEB4 axis.
Shi R, Zhang W, Zhang J, Yu Z, An L, Zhao R, Zhou X, Wang Z, Wei S, Wang H
Journal of translational medicine 2022 Mar 22;20(1):139
Journal of translational medicine 2022 Mar 22;20(1):139
Heat Stress Impairs Maternal Endometrial Integrity and Results in Embryo Implantation Failure by Regulating Transport-Related Gene Expression in Tongcheng Pigs.
Lian W, Gao D, Huang C, Zhong Q, Hua R, Lei M
Biomolecules 2022 Mar 2;12(3)
Biomolecules 2022 Mar 2;12(3)
lncRNA SNHG26 promoted the growth, metastasis, and cisplatin resistance of tongue squamous cell carcinoma through PGK1/Akt/mTOR signal pathway.
Jiang Q, Wang Z, Qi Q, Li J, Xin Y, Qiu J
Molecular therapy oncolytics 2022 Mar 17;24:355-370
Molecular therapy oncolytics 2022 Mar 17;24:355-370
Restraint of chaperonin containing T-complex protein-1 subunit 3 has antitumor roles in non-small cell lung cancer via affection of YAP1.
Shi H, Zhang Y, Wang Y, Fang P, Liu Y, Li W
Toxicology and applied pharmacology 2022 Mar 15;439:115926
Toxicology and applied pharmacology 2022 Mar 15;439:115926
Pan-cancer analysis, cell and animal experiments revealing TEAD4 as a tumor promoter in ccRCC.
Li F, Feng Y, Jiang Q, Zhang J, Wu F, Li Q, Jing X, Wang X, Huang C
Life sciences 2022 Mar 15;293:120327
Life sciences 2022 Mar 15;293:120327
Autophagy-associated circRNA circATG7 facilitates autophagy and promotes pancreatic cancer progression.
He Z, Cai K, Zeng Z, Lei S, Cao W, Li X
Cell death & disease 2022 Mar 14;13(3):233
Cell death & disease 2022 Mar 14;13(3):233
Knockdown of long noncoding RNA MIAT attenuates cigarette smoke-induced airway remodeling by downregulating miR-29c-3p-HIF3A axis.
Gu W, Wang L, Deng G, Gu X, Tang Z, Li S, Jin W, Yang J, Guo X, Li Q
Toxicology letters 2022 Mar 1;357:11-19
Toxicology letters 2022 Mar 1;357:11-19
Bile acids promote the caveolae-associated entry of swine acute diarrhea syndrome coronavirus in porcine intestinal enteroids.
Yang QY, Yang YL, Tang YX, Qin P, Wang G, Xie JY, Chen SX, Ding C, Huang YW, Zhu SJ
PLoS pathogens 2022 Jun;18(6):e1010620
PLoS pathogens 2022 Jun;18(6):e1010620
Blockade of TMEM16A protects against renal fibrosis by reducing intracellular Cl(-) concentration.
Li XL, Liu J, Chen XS, Cheng LM, Liu WL, Chen XF, Li YJ, Guan YY, Zeng X, Du YH
British journal of pharmacology 2022 Jun;179(12):3043-3060
British journal of pharmacology 2022 Jun;179(12):3043-3060
Circular RNA circ_0001459 accelerates hepatocellular carcinoma progression via the miR-6165/IGF1R axis.
Shen D, Zhao H, Zeng P, Ge M, Shrestha S, Zhao W
Annals of the New York Academy of Sciences 2022 Jun;1512(1):46-60
Annals of the New York Academy of Sciences 2022 Jun;1512(1):46-60
A neutrophil-mediated carrier regulates tumor stemness by inhibiting autophagy to prevent postoperative triple-negative breast cancer recurrence and metastasis.
Ren K, He J, Qiu Y, Xu Z, Wang X, Li J, Zang S, Yang Y, Li J, Long Y, Zhang Z, Li M, He Q
Acta biomaterialia 2022 Jun;145:185-199
Acta biomaterialia 2022 Jun;145:185-199
Circ_0005231 promotes the progression of esophageal squamous cell carcinoma via sponging miR-383-5p and regulating KIAA0101.
Sun Z, Zhang S, Zhang N, Wang J, Wang J, Liu J
Thoracic cancer 2022 Jun;13(12):1751-1762
Thoracic cancer 2022 Jun;13(12):1751-1762
Increased susceptibility of irradiated mice to Aspergillus fumigatus infection via NLRP3/GSDMD pathway in pulmonary bronchial epithelia.
Wu DM, He M, Zhao YY, Deng SH, Liu T, Zhang T, Zhang F, Wang YY, Xu Y
Cell communication and signaling : CCS 2022 Jun 27;20(1):98
Cell communication and signaling : CCS 2022 Jun 27;20(1):98
Hydroxychloroquine alleviates renal interstitial fibrosis by inhibiting the PI3K/Akt signaling pathway.
Li D, Yu K, Feng F, Zhang Y, Bai F, Zhang Y, Sun N, Fan J, Liu L, Yang H, Yang X
Biochemical and biophysical research communications 2022 Jun 25;610:154-161
Biochemical and biophysical research communications 2022 Jun 25;610:154-161
Pharmacological Inhibition of Endogenous Hydrogen Sulfide Attenuates Breast Cancer Progression.
Khan NH, Wang D, Wang W, Shahid M, Khattak S, Ngowi EE, Sarfraz M, Ji XY, Zhang CY, Wu DD
Molecules (Basel, Switzerland) 2022 Jun 23;27(13)
Molecules (Basel, Switzerland) 2022 Jun 23;27(13)
Iloprost requires the Frizzled-9 receptor to prevent lung cancer.
Sompel K, Dwyer-Nield LD, Smith AJ, Elango A, Backos DS, Zhang B, Gross J, Ternyak K, Matsuda JL, Kopf K, Keith RL, Tennis MA
iScience 2022 Jun 17;25(6):104442
iScience 2022 Jun 17;25(6):104442
The MIR100HG/miR-29a-3p/Tab1 axis modulates TGF-β1-induced fibrotic changes in type II alveolar epithelial cells BLM-caused lung fibrogenesis in mice.
Guan S, Liu H, Zhou J, Zhang Q, Bi H
Toxicology letters 2022 Jun 15;363:45-54
Toxicology letters 2022 Jun 15;363:45-54
Phenazine derivatives attenuate the stemness of breast cancer cells through triggering ferroptosis.
Yang Y, Lu Y, Zhang C, Guo Q, Zhang W, Wang T, Xia Z, Liu J, Cheng X, Xi T, Jiang F, Zheng L
Cellular and molecular life sciences : CMLS 2022 Jun 11;79(7):360
Cellular and molecular life sciences : CMLS 2022 Jun 11;79(7):360
A signature of circadian rhythm genes in driving anaplastic thyroid carcinoma malignant progression.
Xu T, Jin T, Lu X, Pan Z, Tan Z, Zheng C, Liu Y, Hu X, Ba L, Ren H, Chen J, Zhu C, Ge M, Huang P
Cellular signalling 2022 Jul;95:110332
Cellular signalling 2022 Jul;95:110332
The ETS1-LINC00278 negative feedback loop plays a role in COL4A1/COL4A2 regulation in laryngeal squamous cell carcinoma.
Yang C, Cao H, Yang JW, Wang JT, Yu MM, Wang BS
Neoplasma 2022 Jul;69(4):841-858
Neoplasma 2022 Jul;69(4):841-858
Methylation-mediated expression of SPARC is correlated with tumor progression and poor prognosis of breast cancer.
Li XL, Li JL, Qiu DJ, Ma L
Neoplasma 2022 Jul;69(4):794-806
Neoplasma 2022 Jul;69(4):794-806
LncRNA BACE1-AS promotes the progression of osteosarcoma through miR-762/SOX7 axis.
Wang C, Zhang T, Yang L, Na X, Qu Y
Molecular biology reports 2022 Jul;49(7):5853-5862
Molecular biology reports 2022 Jul;49(7):5853-5862
Overexpression of ERCC6L correlates with poor prognosis and confers malignant phenotypes of lung adenocarcinoma.
Huang X, Jiang L, Lu S, Yuan M, Lin H, Li B, Wen Z, Zhong Y
Oncology reports 2022 Jul;48(1)
Oncology reports 2022 Jul;48(1)
Microfluidic platform for studying the anti-cancer effect of ursolic acid on tumor spheroid.
Chang S, Wen J, Su Y, Ma H
Electrophoresis 2022 Jul;43(13-14):1466-1475
Electrophoresis 2022 Jul;43(13-14):1466-1475
SESN1, negatively regulated by miR-377-3p, suppresses invasive growth of head and neck squamous cell carcinoma by interaction with SMAD3.
Zhang C, Ren L, Zhang H, Yang S, Deng M, He L, Cao R, Zhao C, Xia J
Human cell 2022 Jul;35(4):1100-1113
Human cell 2022 Jul;35(4):1100-1113
Hypoxia-inducible factor-2α promotes EMT in esophageal squamous cell carcinoma through the Notch pathway.
Ji Z, Bao S, Li L, Wang D, Shi M, Liu X
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2022 Jul;31(7):795-805
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2022 Jul;31(7):795-805
Autophagy deficiency promotes lung metastasis of prostate cancer via stabilization of TWIST1.
Shi YX, Sun ZW, Jia DL, Wang HB
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2022 Jul;24(7):1403-1412
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2022 Jul;24(7):1403-1412
LncRNA HOTTIP PROMOTES OVARIAN CANCER CELL INVASION AND METASTASIS BY STABILIZING HIF-1α IN THE ANOXIC CELLULAR MICROENVIRONMENT.
Zhang S, Ma Q, Wu X, Chen P
Acta endocrinologica (Bucharest, Romania : 2005) 2022 Jul-Sep;18(3):263-270
Acta endocrinologica (Bucharest, Romania : 2005) 2022 Jul-Sep;18(3):263-270
Gankyrin modulated non-small cell lung cancer progression via glycolysis metabolism in a YAP1-dependent manner.
Yu T, Liu Y, Xue J, Sun X, Zhu D, Ma L, Guo Y, Jin T, Cao H, Chen Y, Zhu T, Li X, Liang H, Du Z, Shan H
Cell death discovery 2022 Jul 9;8(1):312
Cell death discovery 2022 Jul 9;8(1):312
Sestrin2 remedies podocyte injury via orchestrating TSP-1/TGF-β1/Smad3 axis in diabetic kidney disease.
Song S, Shi C, Bian Y, Yang Z, Mu L, Wu H, Duan H, Shi Y
Cell death & disease 2022 Jul 30;13(7):663
Cell death & disease 2022 Jul 30;13(7):663
Discovery of Novel Phosphoinositide-3-Kinase α Inhibitors with High Selectivity, Excellent Bioavailability, and Long-Acting Efficacy for Gastric Cancer.
Hou Y, Zhang F, Min W, Yuan K, Kuang W, Wang X, Zhu Y, Sun C, Xia F, Wang Y, Zhang H, Wang L, Yang P
Journal of medicinal chemistry 2022 Jul 28;65(14):9873-9892
Journal of medicinal chemistry 2022 Jul 28;65(14):9873-9892
Ginsenoside Rh4 Suppresses Metastasis of Esophageal Cancer and Expression of c-Myc via Targeting the Wnt/β-Catenin Signaling Pathway.
Chen J, Duan Z, Liu Y, Fu R, Zhu C
Nutrients 2022 Jul 25;14(15)
Nutrients 2022 Jul 25;14(15)
Cancer cells corrupt normal epithelial cells through miR-let-7c-rich small extracellular vesicle-mediated downregulation of p53/PTEN.
Liang W, Chen Y, Liu H, Zhao H, Luo T, Tang H, Zhou X, Jiang E, Shao Z, Liu K, Shang Z
International journal of oral science 2022 Jul 19;14(1):36
International journal of oral science 2022 Jul 19;14(1):36
Hyaluronic Acid Modified Nanostructured Lipid Carrier for Targeting Delivery of Kaempferol to NSCLC: Preparation, Optimization, Characterization, and Performance Evaluation In Vitro.
Ma Y, Liu J, Cui X, Hou J, Yu F, Wang J, Wang X, Chen C, Tong L
Molecules (Basel, Switzerland) 2022 Jul 17;27(14)
Molecules (Basel, Switzerland) 2022 Jul 17;27(14)
KIFC3 promotes proliferation, migration and invasion of esophageal squamous cell carcinoma cells by activating EMT and β-catenin signaling.
Hao WW, Xu F
World journal of gastrointestinal oncology 2022 Jul 15;14(7):1239-1251
World journal of gastrointestinal oncology 2022 Jul 15;14(7):1239-1251
Expansion of mouse castration-resistant intermediate prostate stem cells in vitro.
Xu Y, Mu J, Zhou Z, Leng Y, Yu Y, Song X, Liu A, Zhu H, Li J, Wang D
Stem cell research & therapy 2022 Jul 15;13(1):299
Stem cell research & therapy 2022 Jul 15;13(1):299
RBM47 inhibits hepatocellular carcinoma progression by targeting UPF1 as a DNA/RNA regulator.
Guo T, You K, Chen X, Sun Y, Wu Y, Wu P, Jiang Y
Cell death discovery 2022 Jul 14;8(1):320
Cell death discovery 2022 Jul 14;8(1):320
Rosmarinic Acid Decreases the Malignancy of Pancreatic Cancer Through Inhibiting Gli1 Signaling.
Zhou X, Wang W, Li Z, Chen L, Wen C, Ruan Q, Xu Z, Liu R, Xu J, Bai Y, Deng J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153861
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153861
Histone deacetylase 6-mediated downregulation of TMEM100 expedites the development and progression of non-small cell lung cancer.
Wang Y, Ha M, Li M, Zhang L, Chen Y
Human cell 2022 Jan;35(1):271-285
Human cell 2022 Jan;35(1):271-285
IGF2BP3 promotes cell metastasis and is associated with poor patient survival in nasopharyngeal carcinoma.
Xu Y, Guo Z, Peng H, Guo L, Wang P
Journal of cellular and molecular medicine 2022 Jan;26(2):410-421
Journal of cellular and molecular medicine 2022 Jan;26(2):410-421
Jolkinolide B alleviates renal fibrosis via anti-inflammation and inhibition of epithelial-mesenchymal transition in unilateral ureteral obstruction mice.
Li M, Yan Y, He J, Wang YM, Guo YX, Wang ZX, Zhang WK, Zhang HJ, Xu JK
Journal of Asian natural products research 2022 Jan;24(1):76-87
Journal of Asian natural products research 2022 Jan;24(1):76-87
Deubiquitinase USP13 promotes the epithelial-mesenchymal transition and metastasis in gastric cancer by maintaining Snail protein.
Zhang T, Zheng J, Qiao L, Zhao W
Pathology, research and practice 2022 Jan;229:153705
Pathology, research and practice 2022 Jan;229:153705
MICAL1 inhibits colorectal cancer cell migration and proliferation by regulating the EGR1/β-catenin signaling pathway.
Gu H, Li Y, Cui X, Cao H, Hou Z, Ti Y, Liu D, Gao J, Wang Y, Wen P
Biochemical pharmacology 2022 Jan;195:114870
Biochemical pharmacology 2022 Jan;195:114870
Etoposide-induced protein 2.4 ameliorates high glucose-induced epithelial-mesenchymal transition by activating adenosine monophosphate-activated protein kinase pathway in renal tubular cells.
Li F, Guo D, Zhi S, Jia K, Wang Y, Zhang A, Pei Y, Hao J
The international journal of biochemistry & cell biology 2022 Jan;142:106117
The international journal of biochemistry & cell biology 2022 Jan;142:106117
circUSP34 accelerates osteosarcoma malignant progression by sponging miR-16-5p.
Lou J, Zhang H, Xu J, Ren T, Huang Y, Tang X, Guo W
Cancer science 2022 Jan;113(1):120-131
Cancer science 2022 Jan;113(1):120-131
Inhibition of the proliferation, invasion, migration, and epithelial-mesenchymal transition of prostate cancer cells through the action of ATP1A2 on the TGF-β/Smad pathway.
Zhang B, Zhu Z, Zhang X, Li F, Ding A
Translational andrology and urology 2022 Jan;11(1):53-66
Translational andrology and urology 2022 Jan;11(1):53-66
YTHDF3 facilitates triple-negative breast cancer progression and metastasis by stabilizing ZEB1 mRNA in an m(6)A-dependent manner.
Lin Y, Jin X, Nie Q, Chen M, Guo W, Chen L, Li Y, Chen X, Zhang W, Chen H, Jiang M, Xiao H, Zhang J, Fu F, Wang C
Annals of translational medicine 2022 Jan;10(2):83
Annals of translational medicine 2022 Jan;10(2):83
HSP90AB1 Promotes the Proliferation, Migration, and Glycolysis of Head and Neck Squamous Cell Carcinoma.
Zhang H, Yin X, Zhang X, Zhou M, Xu W, Wei Z, Song C, Han S, Han W
Technology in cancer research & treatment 2022 Jan-Dec;21:15330338221118202
Technology in cancer research & treatment 2022 Jan-Dec;21:15330338221118202
G-protein Coupled Receptor 34 Promotes Gliomagenesis by Inducing Proliferation and Malignant Phenotype via TGF-Beta/Smad Signaling Pathway.
Cheng Y, Heng X, Feng F
Technology in cancer research & treatment 2022 Jan-Dec;21:15330338221105733
Technology in cancer research & treatment 2022 Jan-Dec;21:15330338221105733
miR-498 Targets UBE2T to Inhibit the Proliferation of Malignant Melanoma Cells.
Cao W, Ni L, Li P, Wang QX, Li MM, Huang SH, Dang NN
Technology in cancer research & treatment 2022 Jan-Dec;21:15330338221082431
Technology in cancer research & treatment 2022 Jan-Dec;21:15330338221082431
STK25 enhances hepatocellular carcinoma progression through the STRN/AMPK/ACC1 pathway.
Zhang Y, Xu J, Qiu Z, Guan Y, Zhang X, Zhang X, Chai D, Chen C, Hu Q, Wang W
Cancer cell international 2022 Jan 5;22(1):4
Cancer cell international 2022 Jan 5;22(1):4
Circ_0078607 inhibits the progression of ovarian cancer via regulating the miR-32-5p/SIK1 network.
Jin Y, Wang H
Journal of ovarian research 2022 Jan 4;15(1):3
Journal of ovarian research 2022 Jan 4;15(1):3
Circular RNA circCSPP1 promotes the occurrence and development of colon cancer by sponging miR-431 and regulating ROCK1 and ZEB1.
Wang J, Zhou L, Chen B, Yu Z, Zhang J, Zhang Z, Hu C, Bai Y, Ruan X, Wang S, Ouyang J, Wu A, Zhao X
Journal of translational medicine 2022 Jan 31;20(1):58
Journal of translational medicine 2022 Jan 31;20(1):58
HERC3 regulates epithelial-mesenchymal transition by directly ubiquitination degradation EIF5A2 and inhibits metastasis of colorectal cancer.
Zhang Z, He G, Lv Y, Liu Y, Niu Z, Feng Q, Hu R, Xu J
Cell death & disease 2022 Jan 21;13(1):74
Cell death & disease 2022 Jan 21;13(1):74
lncRNA PCAT1 might coordinate ZNF217 to promote CRC adhesion and invasion through regulating MTA2/MTA3/Snai1/E-cadherin signaling.
Zhang S, Zhu K, Han Q, Wang Q, Yang B
Cellular and molecular biology (Noisy-le-Grand, France) 2022 Jan 2;67(4):1-9
Cellular and molecular biology (Noisy-le-Grand, France) 2022 Jan 2;67(4):1-9
Extracellular vesicles released by non-small cell lung cancer cells drive invasion and permeability in non-tumorigenic lung epithelial cells.
Hasan H, Sohal IS, Soto-Vargas Z, Byappanahalli AM, Humphrey SE, Kubo H, Kitdumrongthum S, Copeland S, Tian F, Chairoungdua A, Kasinski AL
Scientific reports 2022 Jan 19;12(1):972
Scientific reports 2022 Jan 19;12(1):972
Identification of Pyruvate Carboxylase as the Cellular Target of Natural Bibenzyls with Potent Anticancer Activity against Hepatocellular Carcinoma via Metabolic Reprogramming.
Sheng Y, Chen Y, Zeng Z, Wu W, Wang J, Ma Y, Lin Y, Zhang J, Huang Y, Li W, Zhu Q, Wei X, Li S, Wisanwattana W, Li F, Liu W, Suksamrarn A, Zhang G, Jiao W, Wang F
Journal of medicinal chemistry 2022 Jan 13;65(1):460-484
Journal of medicinal chemistry 2022 Jan 13;65(1):460-484
ZC3H15 promotes glioblastoma progression through regulating EGFR stability.
Hou J, Xu M, Gu H, Pei D, Liu Y, Huang P, Chang H, Cui H
Cell death & disease 2022 Jan 13;13(1):55
Cell death & disease 2022 Jan 13;13(1):55
CACNA1B facilitates breast cancer cell growth and migration by regulating cyclin D1 and EMT: the implication of CACNA1B in breast cancer.
Jin YM, Ye Y, Bao WQ, Tong Y, Ni SB, Liu JP, Zhao B
Journal of receptor and signal transduction research 2022 Feb;42(1):1-8
Journal of receptor and signal transduction research 2022 Feb;42(1):1-8
FGD3 binds with HSF4 to suppress p65 expression and inhibit pancreatic cancer progression.
Guo F, Cheng X, Jing B, Wu H, Jin X
Oncogene 2022 Feb;41(6):838-851
Oncogene 2022 Feb;41(6):838-851
The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer.
Li M, Rao X, Cui Y, Zhang L, Li X, Wang B, Zheng Y, Teng L, Zhou T, Zhuo W
Oncogene 2022 Feb;41(6):770-781
Oncogene 2022 Feb;41(6):770-781
Ginkgo biloba Extract Inhibited Cell Proliferation and Invasion by Stimulating TET2 Expression Through miR-29a in Colorectal Carcinoma Cells.
Li C, Peng C, Jiang Z, Hu H, Lin C, Gao Y, Liu D, Sun B, Wang D
DNA and cell biology 2022 Feb;41(2):169-178
DNA and cell biology 2022 Feb;41(2):169-178
MiR-4521 plays a tumor repressive role in growth and metastasis of hepatocarcinoma cells by suppressing phosphorylation of FAK/AKT pathway via targeting FAM129A.
Ayesha M, Majid A, Zhao D, Greenaway FT, Yan N, Liu Q, Liu S, Sun MZ
Journal of advanced research 2022 Feb;36:147-161
Journal of advanced research 2022 Feb;36:147-161
The cancer-testis lncRNA lnc-CTHCC promotes hepatocellular carcinogenesis by binding hnRNP K and activating YAP1 transcription.
Xia A, Yuan W, Wang Q, Xu J, Gu Y, Zhang L, Chen C, Wang Z, Wu D, He Q, Yu W, Wang F, Xue C, Zhang Y, Bao G, Tao X, Liu S, Wang S, Hu Z, Sun B
Nature cancer 2022 Feb;3(2):203-218
Nature cancer 2022 Feb;3(2):203-218
Dihydrotestosterone through blockade of TGF-β/Smad signaling mediates the anti-fibrosis effect under hypoxia in canine Sertoli cells.
Xiao L, Wang Z, Lu N, Wei H, Kang J, Yuan M, Sheng X, Qi X, Xing K, Guo Y, Wang X, Zhao J, Gao Y, Ni H
The Journal of steroid biochemistry and molecular biology 2022 Feb;216:106041
The Journal of steroid biochemistry and molecular biology 2022 Feb;216:106041
Nc886 promotes renal cancer cell drug-resistance by enhancing EMT through Rock2 phosphorylation-mediated β-catenin nuclear translocation.
Gao W, Zhang S, Guorong L, Liu Q, Zhu A, Gui F, Zou Y, Wu Y, Luo Y, Hong Z
Cell cycle (Georgetown, Tex.) 2022 Feb;21(4):340-351
Cell cycle (Georgetown, Tex.) 2022 Feb;21(4):340-351
Cancer-associated fibroblasts promote tumor progression by lncRNA-mediated RUNX2/GDF10 signaling in oral squamous cell carcinoma.
Zhang D, Song Y, Li D, Liu X, Pan Y, Ding L, Shi G, Wang Y, Ni Y, Hou Y
Molecular oncology 2022 Feb;16(3):780-794
Molecular oncology 2022 Feb;16(3):780-794
Ubiquitin-specific peptidase 2 inhibits epithelial-mesenchymal transition in clear cell renal cell carcinoma metastasis by downregulating the NF-κB pathway.
Duan J, Jin M, Yang D, Shi J, Gao J, Guo D, Tang H, Zhang S, Qiao B
Bioengineered 2022 Feb;13(2):4455-4467
Bioengineered 2022 Feb;13(2):4455-4467
Foxhead box D1 promotes the partial epithelial-to-mesenchymal transition of laryngeal squamous cell carcinoma cells via transcriptionally activating the expression of zinc finger protein 532.
Fan L, Wang J, Deng P, Wang Y, Zhang A, Yang M, Zeng G
Bioengineered 2022 Feb;13(2):3057-3069
Bioengineered 2022 Feb;13(2):3057-3069
Hyperglycemia induces miR-26-5p down-regulation to overexpress PFKFB3 and accelerate epithelial-mesenchymal transition in gastric cancer.
He X, Cheng X, Ding J, Xiong M, Chen B, Cao G
Bioengineered 2022 Feb;13(2):2902-2917
Bioengineered 2022 Feb;13(2):2902-2917
tRF-19-W4PU732S promotes breast cancer cell malignant activity by targeting inhibition of RPL27A (ribosomal protein-L27A).
Zhang Z, Liu Z, Zhao W, Zhao X, Tao Y
Bioengineered 2022 Feb;13(2):2087-2098
Bioengineered 2022 Feb;13(2):2087-2098
MiR-187 regulates the proliferation, migration and invasion of human trophoblast cells by repressing BCL6-mediated activation of PI3K/AKT signaling.
Chen X, Song QL, Ji R, Wang JY, Li ZH, Guo D, Yin TL, Wang SJ, Yang J
Placenta 2022 Feb;118:20-31
Placenta 2022 Feb;118:20-31
TCOF1 coordinates oncogenic activation and rRNA production and promotes tumorigenesis in HCC.
Wu C, Xia D, Wang D, Wang S, Sun Z, Xu B, Zhang D
Cancer science 2022 Feb;113(2):553-564
Cancer science 2022 Feb;113(2):553-564
HDAC9 Contributes to Serous Ovarian Cancer Progression through Regulating Epithelial-Mesenchymal Transition.
Xu L, Wang J, Liu B, Fu J, Zhao Y, Yu S, Shen L, Yan X, Su J
Biomedicines 2022 Feb 3;10(2)
Biomedicines 2022 Feb 3;10(2)
Effects of Exopolysaccharides from Lactiplantibacillus plantarum JLAU103 on Intestinal Immune Response, Oxidative Stress, and Microbial Communities in Cyclophosphamide-Induced Immunosuppressed Mice.
Wang J, Li M, Gao Y, Li H, Fang L, Liu C, Liu X, Min W
Journal of agricultural and food chemistry 2022 Feb 23;70(7):2197-2210
Journal of agricultural and food chemistry 2022 Feb 23;70(7):2197-2210
YTHDF1 promotes breast cancer progression by facilitating FOXM1 translation in an m6A-dependent manner.
Chen H, Yu Y, Yang M, Huang H, Ma S, Hu J, Xi Z, Guo H, Yao G, Yang L, Huang X, Zhang F, Tan G, Wu H, Zheng W, Li L
Cell & bioscience 2022 Feb 23;12(1):19
Cell & bioscience 2022 Feb 23;12(1):19
Ginkgo biloba leaf extract mitigates cisplatin-induced chronic renal interstitial fibrosis by inhibiting the epithelial-mesenchymal transition of renal tubular epithelial cells mediated by the Smad3/TGF-β1 and Smad3/p38 MAPK pathways.
Wei C, Zhang Y, Zhong X, Lu S, Zou X, Yang Y, Huang S, Huang Z
Chinese medicine 2022 Feb 21;17(1):25
Chinese medicine 2022 Feb 21;17(1):25
Programmed death-ligand 1 signaling and expression are reversible by lycopene via PI3K/AKT and Raf/MEK/ERK pathways in tongue squamous cell carcinoma.
Peng M, Fan S, Li J, Zhou X, Liao Q, Tang F, Liu W
Genes & nutrition 2022 Feb 14;17(1):3
Genes & nutrition 2022 Feb 14;17(1):3
ZHX2 inhibits thyroid cancer metastasis through transcriptional inhibition of S100A14.
Zhang Y, Sun M, Gao L, Liang X, Ma C, Lu J, Yue X
Cancer cell international 2022 Feb 12;22(1):76
Cancer cell international 2022 Feb 12;22(1):76
Ginsenoside Rh4 Suppressed Metastasis of Lung Adenocarcinoma via Inhibiting JAK2/STAT3 Signaling.
Zhang Y, Ma P, Duan Z, Liu Y, Mi Y, Fan D
International journal of molecular sciences 2022 Feb 11;23(4)
International journal of molecular sciences 2022 Feb 11;23(4)
A novel immune-related lncRNA pair signature for prognostic prediction and immune response evaluation in gastric cancer: a bioinformatics and biological validation study.
Wang J, Wang B, Zhou B, Chen J, Qi J, Shi L, Yu S, Chen G, Kang M, Jin X, Wang L, Xu J, Zhu L, Chen J
Cancer cell international 2022 Feb 10;22(1):69
Cancer cell international 2022 Feb 10;22(1):69
ID2 inhibits lung adenocarcinoma cell malignant behaviors by inhibiting the activation of the PI3K/AKT/mTOR signaling pathway.
Peng W, Chen J, He R, Tang Y, Jiang J, Li Y
Tissue & cell 2022 Dec;79:101950
Tissue & cell 2022 Dec;79:101950
CircCERS6 Suppresses the Development of Epithelial Ovarian Cancer Through Mediating miR-630/RASSF8.
Li X, Jiang X, Lu J, Lin Y, Jiang L, Li Y, Wan F, Wang C
Biochemical genetics 2022 Dec;60(6):2611-2629
Biochemical genetics 2022 Dec;60(6):2611-2629
Study on the biological mechanism of urolithin a on nasopharyngeal carcinoma in vitro.
Yang Y, Ren ZZ, Wei WJ, He ZL, Deng YL, Wang Z, Fan YC, Zhou J, Jiang LH
Pharmaceutical biology 2022 Dec;60(1):1566-1577
Pharmaceutical biology 2022 Dec;60(1):1566-1577
Anti-EMT and anti-fibrosis effects of protocatechuic aldehyde in renal proximal tubular cells and the unilateral ureteral obstruction animal model.
Chang YT, Chung MC, Chang CH, Chiu KH, Shieh JJ, Wu MJ
Pharmaceutical biology 2022 Dec;60(1):1198-1206
Pharmaceutical biology 2022 Dec;60(1):1198-1206
PD-L1/PD-L1 signalling promotes colorectal cancer cell migration ability through RAS/MEK/ERK.
Cao Y, Liang W, Fang L, Liu MK, Zuo J, Peng YL, Shan JJ, Sun RX, Zhao J, Wang J
Clinical and experimental pharmacology & physiology 2022 Dec;49(12):1281-1293
Clinical and experimental pharmacology & physiology 2022 Dec;49(12):1281-1293
Inhibition of Circ-Snrk ameliorates apoptosis and inflammation in acute kidney injury by regulating the MAPK pathway.
Meng F, Chen Q, Gu S, Cui R, Ma Q, Cao R, Zhao M
Renal failure 2022 Dec;44(1):672-681
Renal failure 2022 Dec;44(1):672-681
Relaxin inhibits renal fibrosis and the epithelial-to-mesenchymal transition via the Wnt/β-catenin signaling pathway.
Feiteng C, Lei C, Deng L, Chaoliang X, Zijie X, Yi S, Minglei S
Renal failure 2022 Dec;44(1):513-524
Renal failure 2022 Dec;44(1):513-524
Cystathionine γ-lyase mediates cell proliferation, migration, and invasion of nasopharyngeal carcinoma.
Zhang Q, Gao Y, Zhang Y, Jing M, Wang D, Wang Y, Khattak S, Qi H, Cai C, Zhang J, Ngowi EE, Khan NH, Li T, Ji A, Jiang Q, Ji X, Li Y, Wu D
Oncogene 2022 Dec;41(49):5238-5252
Oncogene 2022 Dec;41(49):5238-5252
CUL4B increases platinum-based drug resistance in colorectal cancer through EMT: A study in its mechanism.
Luo JW, Wang CM, Su JW, Yi TZ, Tang SH
Journal of cellular and molecular medicine 2022 Dec;26(23):5767-5778
Journal of cellular and molecular medicine 2022 Dec;26(23):5767-5778
IRF2-ferroptosis related gene is associated with prognosis and EMT in gliomas.
Tong S, Ye L, Xu Y, Sun Q, Gao L, Cai J, Ye Z, Tian D, Chen Q
Translational oncology 2022 Dec;26:101544
Translational oncology 2022 Dec;26:101544
ALG2 inhibits the epithelial-to-mesenchymal transition and stemness of ovarian granulosa cells through the Wnt/β-catenin signaling pathway in polycystic ovary syndrome.
Zheng Q, Liu M, Fu J
Reproductive biology 2022 Dec;22(4):100706
Reproductive biology 2022 Dec;22(4):100706
CircRNA PVT1 modulated cell migration and invasion through Epithelial-Mesenchymal Transition (EMT) mediation in gastric cancer through miR-423-5p/Smad3 pathway.
Li H, Xue S, Zhang X, Li F, Bei S, Feng L
Regenerative therapy 2022 Dec;21:25-33
Regenerative therapy 2022 Dec;21:25-33
Genomic and expressional dynamics of ovarian cancer cell lines in PARPi treatment revealed mechanisms of acquired resistance.
Cheng A, Rao Q, Liu Y, Huang C, Li J, Huo C, Lin Z, Lu H
Gynecologic oncology 2022 Dec;167(3):502-512
Gynecologic oncology 2022 Dec;167(3):502-512
Carbon dots enhance extracellular matrix secretion for dentin-pulp complex regeneration through PI3K/Akt/mTOR pathway-mediated activation of autophagy.
Liu L, Li X, Bu W, Jin N, Meng Y, Wang Y, Wang D, Xu X, Zhou D, Sun H
Materials today. Bio 2022 Dec;16:100344
Materials today. Bio 2022 Dec;16:100344
Artemisitene suppresses rheumatoid arthritis progression via modulating METTL3-mediated N6-methyladenosine modification of ICAM2 mRNA in fibroblast-like synoviocytes.
Chen J, Lin X, He J, Liu D, He L, Zhang M, Luan H, Hu Y, Tao C, Wang Q
Clinical and translational medicine 2022 Dec;12(12):e1148
Clinical and translational medicine 2022 Dec;12(12):e1148
Silencing of lncRNA SNHG17 inhibits the tumorigenesis of epithelial ovarian cancer through regulation of miR-485-5p/AKT1 axis.
Wang W, Yu S, Li W, Hu H, Zou G
Biochemical and biophysical research communications 2022 Dec 31;637:117-126
Biochemical and biophysical research communications 2022 Dec 31;637:117-126
Exosome-transmitted S100A4 induces immunosuppression and non-small cell lung cancer development by activating STAT3.
Wu X, Zhang H, Jiang G, Peng M, Li C, Lu J, Jiang S, Yang X, Jiang Y
Clinical and experimental immunology 2022 Dec 31;210(3):309-320
Clinical and experimental immunology 2022 Dec 31;210(3):309-320
Construction and validation of a prognostic model for osteosarcoma patients based on autophagy-related genes.
Ning B, Liu Y, Xu T, Li Y, Wei D, Huang T, Wei Y
Discover oncology 2022 Dec 31;13(1):146
Discover oncology 2022 Dec 31;13(1):146
lncRNA ZNRD1-AS1 promotes malignant lung cell proliferation, migration, and angiogenesis via the miR-942/TNS1 axis and is positively regulated by the m(6)A reader YTHDC2.
Wang J, Tan L, Yu X, Cao X, Jia B, Chen R, Li J
Molecular cancer 2022 Dec 30;21(1):229
Molecular cancer 2022 Dec 30;21(1):229
FAT4 activation inhibits epithelial-mesenchymal transition (EMT) by promoting autophagy in H2228/Cer cells.
Yang Y, Li Y, Yang Q, Liu Z, Chang X, Yang H, Liu J, Li Z, Zuo D
Medical oncology (Northwood, London, England) 2022 Dec 28;40(1):64
Medical oncology (Northwood, London, England) 2022 Dec 28;40(1):64
Krüppel-like Factor 13 Promotes HCC Progression by Transcriptional Regulation of HMGCS1-mediated Cholesterol Synthesis.
Chen CC, Xie XM, Zhao XK, Zuo S, Li HY
Journal of clinical and translational hepatology 2022 Dec 28;10(6):1125-1137
Journal of clinical and translational hepatology 2022 Dec 28;10(6):1125-1137
Dihydromyricetin Attenuates High-Intensity Exercise-Induced Intestinal Barrier Dysfunction Associated with the Modulation of the Phenotype of Intestinal Intraepithelial Lymphocytes.
Hou P, Wang D, Lang H, Yao Y, Zhou J, Zhou M, Zhu J, Yi L, Mi M
International journal of molecular sciences 2022 Dec 23;24(1)
International journal of molecular sciences 2022 Dec 23;24(1)
Increased expression of miR-194-5p through the circPVRL3/miR-194-5p/SOCS2 axis promotes proliferation and metastasis in pancreatic ductal adenocarcinoma by activating the PI3K/AKT signaling pathway.
Chi B, Zheng Y, Xie F, Fu W, Wang X, Gu J, Yang J, Yin J, Cai L, Tang P, Li J, Guo S, Wang H
Cancer cell international 2022 Dec 20;22(1):415
Cancer cell international 2022 Dec 20;22(1):415
A multifunctional black phosphorus-based adhesive patch intrinsically induces partial EMT for effective burn wound healing.
Wang X, Tang X, Li N, Sun Y, Yu R, Zhang J, Li D, Yang B, Sun H
Biomaterials science 2022 Dec 20;11(1):235-247
Biomaterials science 2022 Dec 20;11(1):235-247
Novel shikonin derivatives suppress cell proliferation, migration and induce apoptosis in human triple-negative breast cancer cells via regulating PDK1/PDHC axis.
Chen Q, Han H, Lin F, Yang L, Feng L, Lai X, Wen Z, Yang M, Wang C, Ma Y, Yin T, Lu G, Lin H, Qi J, Yang Y
Life sciences 2022 Dec 1;310:121077
Life sciences 2022 Dec 1;310:121077
Identification of endocrine-disrupting chemicals targeting the genes and pathways of genital anomalies in males.
Zhou X, Zhang X, Zhou X, Abulimiti G, Wang Y, Zhang Q, Cong R, Ji C, Luan J, Yao L, Yang J, Song N
Ecotoxicology and environmental safety 2022 Dec 1;247:114241
Ecotoxicology and environmental safety 2022 Dec 1;247:114241
FTO mediated ERBB2 demethylation promotes tumor progression in esophageal squamous cell carcinoma cells.
Zhao F, Ge F, Xie M, Li Z, Zang C, Kong L, Pu Y, Zheng X, Tan Y
Clinical & experimental metastasis 2022 Aug;39(4):623-639
Clinical & experimental metastasis 2022 Aug;39(4):623-639
Suppression of rhomboid domain-containing 1 produces anticancer effects in pancreatic adenocarcinoma through affection of the AKT/GSK-3β/β-catenin pathway.
Jiang J, Cheng Y, Dai S, Zou B, Guo X
Environmental toxicology 2022 Aug;37(8):1944-1956
Environmental toxicology 2022 Aug;37(8):1944-1956
XIST sponges miR-320d to promote chordoma progression by regulating ARF6.
Wang Y, Tang Z, Guo W
Journal of bone oncology 2022 Aug;35:100447
Journal of bone oncology 2022 Aug;35:100447
Ferrostatin‑1 alleviates oxalate‑induced renal tubular epithelial cell injury, fibrosis and calcium oxalate stone formation by inhibiting ferroptosis.
Xie J, Ye Z, Li L, Xia Y, Yuan R, Ruan Y, Zhou X
Molecular medicine reports 2022 Aug;26(2)
Molecular medicine reports 2022 Aug;26(2)
Downstream Neighbor of Son Overexpression is Associated With Breast Cancer Progression and a Poor Prognosis.
Qi Y, Wu H, Liu C, Zheng D, Yan C, Hu W, Zhang X, Dai X
Journal of breast cancer 2022 Aug;25(4):327-343
Journal of breast cancer 2022 Aug;25(4):327-343
Agmatinase facilitates the tumorigenesis of pancreatic adenocarcinoma through the TGFβ/Smad pathway.
Zhang Y, Cao L, Xie Y, Wang C, Liu X, Zhang X, Chen J
Experimental and therapeutic medicine 2022 Aug;24(2):490
Experimental and therapeutic medicine 2022 Aug;24(2):490
Nav1.6 promotes the progression of human follicular thyroid carcinoma cells via JAK-STAT signaling pathway.
Li H, Liu J, Fan N, Wang H, Thomas AM, Yan Q, Li S, Qin H
Pathology, research and practice 2022 Aug;236:153984
Pathology, research and practice 2022 Aug;236:153984
Forkhead box A2 transcriptionally activates hsa-let-7 g to inhibit hypoxia-induced epithelial-mesenchymal transition by targeting c14orf28 in colorectal cancer.
Ouyang C, Fu Q, Xie Y, Xie J
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology 2022 Aug;23(3):188-194
Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology 2022 Aug;23(3):188-194
Design, Synthesis and Anti-Tumor Activity Evaluation of Novel 3,4-(Methylenedioxy)cinnamic Acid Amide-Dithiocarbamate Derivatives.
Guo J, Cheng M, Liu P, Cao D, Luo J, Wan Y, Wang R, Fang Y, Jin Y, Zhang Z, Xie SS, Liu J
Chemistry & biodiversity 2022 Aug;19(8):e202200439
Chemistry & biodiversity 2022 Aug;19(8):e202200439
HIF-1α induced NID1 expression promotes pulmonary metastases via the PI3K-AKT pathway in salivary gland adenoid cystic carcinoma.
Han N, Li X, Wang Y, Li H, Zhang C, Zhao X, Zhang Z, Ruan M, Zhang C
Oral oncology 2022 Aug;131:105940
Oral oncology 2022 Aug;131:105940
LncRNA SNHG11 promotes the malignant transformation of human bronchial epithelial cells induced by beryllium sulfate.
Deng W, Sun Z, Chen S, Li G, Liu X, Huang L, Zhang Z
Toxicology research 2022 Aug;11(4):605-615
Toxicology research 2022 Aug;11(4):605-615
PEBP4 Directs the Malignant Behavior of Hepatocellular Carcinoma Cells via Regulating mTORC1 and mTORC2.
Chen Q, Jin J, Guo W, Tang Z, Luo Y, Ying Y, Lin H, Luo Z
International journal of molecular sciences 2022 Aug 8;23(15)
International journal of molecular sciences 2022 Aug 8;23(15)
Long noncoding RNA CERS6-AS1 modulates glucose metabolism and tumor progression in hepatocellular carcinoma by promoting the MDM2/p53 signaling pathway.
Xu B, Wei Y, Liu F, Li L, Zhou S, Peng Y, Li B
Cell death discovery 2022 Aug 4;8(1):348
Cell death discovery 2022 Aug 4;8(1):348
The LINC00623/NAT10 signaling axis promotes pancreatic cancer progression by remodeling ac4C modification of mRNA.
Feng Z, Li K, Qin K, Liang J, Shi M, Ma Y, Zhao S, Liang H, Han D, Shen B, Peng C, Chen H, Jiang L
Journal of hematology & oncology 2022 Aug 17;15(1):112
Journal of hematology & oncology 2022 Aug 17;15(1):112
Construction of a novel model based on cell-in-cell-related genes and validation of KRT7 as a biomarker for predicting survival and immune microenvironment in pancreatic cancer.
Song J, Ruze R, Chen Y, Xu R, Yin X, Wang C, Xu Q, Zhao Y
BMC cancer 2022 Aug 16;22(1):894
BMC cancer 2022 Aug 16;22(1):894
FAM107A Inactivation Associated with Promoter Methylation Affects Prostate Cancer Progression through the FAK/PI3K/AKT Pathway.
Ke S, Liu Z, Wang Q, Zhai G, Shao H, Yu X, Guo J
Cancers 2022 Aug 13;14(16)
Cancers 2022 Aug 13;14(16)
miR-596-3p suppresses brain metastasis of non-small cell lung cancer by modulating YAP1 and IL-8.
Li C, Zheng H, Xiong J, Huang Y, Li H, Jin H, Ai S, Wang Y, Su T, Sun G, Xiao X, Fu T, Wang Y, Gao X, Liang P
Cell death & disease 2022 Aug 12;13(8):699
Cell death & disease 2022 Aug 12;13(8):699
PDCD10 promotes the aggressive behaviors of pituitary adenomas by up-regulating CXCR2 and activating downstream AKT/ERK signaling.
Liu J, Wang J, Tian W, Xu Y, Li R, Zhao K, You C, Zhu Y, Bartsch JW, Niu H, Zhang H, Shu K, Lei T
Aging 2022 Aug 11;14(15):6066-6080
Aging 2022 Aug 11;14(15):6066-6080
Jianpi Huayu decoction inhibits the epithelial-mesenchymal transition of hepatocellular carcinoma cells by suppressing exosomal miR-23a-3p/Smad signaling.
Xie CF, Feng KL, Wang JN, Luo R, Fang CK, Zhang Y, Shen CP, Zhong C
Journal of ethnopharmacology 2022 Aug 10;294:115360
Journal of ethnopharmacology 2022 Aug 10;294:115360
SEC14L3 plays a tumor-suppressive role in breast cancer through a Wnt/β-catenin-related way.
Zhu Q, Wan NB, Deng HW, Lu LL, Zhang Y, He X, Liu H, He Y
Experimental cell research 2022 Aug 1;417(1):113161
Experimental cell research 2022 Aug 1;417(1):113161
Downregulation of CPT2 promotes proliferation and inhibits apoptosis through p53 pathway in colorectal cancer.
Liu F, Li X, Yan H, Wu J, Yang Y, He J, Chen J, Jiang Z, Wu F, Jiang Z
Cellular signalling 2022 Apr;92:110267
Cellular signalling 2022 Apr;92:110267
EML4-ALK G1202R mutation induces EMT and confers resistance to ceritinib in NSCLC cells via activation of STAT3/Slug signaling.
Shen J, Meng Y, Wang K, Gao M, Du J, Wang J, Li Z, Zuo D, Wu Y
Cellular signalling 2022 Apr;92:110264
Cellular signalling 2022 Apr;92:110264
Hsa_circRNA_0017620 regulated cell progression of non-small-cell lung cancer via miR-520a-5p/KRT5 axis.
Chen S, Hong K, Zhou L, Ran R, Huang J, Zheng Y, Xing M, Cai Y
Journal of clinical laboratory analysis 2022 Apr;36(4):e24347
Journal of clinical laboratory analysis 2022 Apr;36(4):e24347
Myricetin reverses epithelial-endothelial transition and inhibits vasculogenic mimicry and angiogenesis of hepatocellular carcinoma by directly targeting PAR1.
Wang M, Ren S, Bi Z, Zhang L, Cui M, Sun R, Bao J, Gao D, Yang B, Li X, Li M, Xiao T, Zhou HG, Yang C
Phytotherapy research : PTR 2022 Apr;36(4):1807-1821
Phytotherapy research : PTR 2022 Apr;36(4):1807-1821
Tumor-specific nitric oxide generator to amplify peroxynitrite based on highly penetrable nanoparticles for metastasis inhibition and enhanced cancer therapy.
Shi M, Zhang J, Wang Y, Peng C, Hu H, Qiao M, Zhao X, Chen D
Biomaterials 2022 Apr;283:121448
Biomaterials 2022 Apr;283:121448
Apatinib inhibits tumour progression and promotes antitumour efficacy of cytotoxic drugs in oesophageal squamous cell carcinoma.
Chi Y, Wang F, Zhang Y, Shan Z, Tao W, Lian Y, Xin D, Fan Q, Sun Y
Journal of cellular and molecular medicine 2022 Apr;26(7):1905-1917
Journal of cellular and molecular medicine 2022 Apr;26(7):1905-1917
Gelsolin impairs barrier function in pancreatic ductal epithelial cells by actin filament depolymerization in hypertriglyceridemia-induced pancreatitis in vitro.
Yang HY, Liang ZH, Xie JL, Wu Q, Qin YY, Zhang SY, Tang GD
Experimental and therapeutic medicine 2022 Apr;23(4):290
Experimental and therapeutic medicine 2022 Apr;23(4):290
Epiplakin1 promotes the progression of esophageal squamous cell carcinoma by activating the PI3K-AKT signaling pathway.
Qiao Z, Dai C, Wang Z, Wang Z, Wang Z, Zhang T, Niu W, Ma X
Thoracic cancer 2022 Apr;13(8):1117-1125
Thoracic cancer 2022 Apr;13(8):1117-1125
circHIPK3 regulates cell proliferation and migration by sponging microRNA-124 and regulating serine/threonine kinase 3 expression in esophageal squamous cell carcinoma.
Yao D, Lin S, Chen S, Wang Z
Bioengineered 2022 Apr;13(4):9767-9780
Bioengineered 2022 Apr;13(4):9767-9780
Terpinen-4-ol inhibits the proliferation and mobility of pancreatic cancer cells by downregulating Rho-associated coiled-coil containing protein kinase 2.
Cao W, Tian R, Pan R, Sun B, Xiao C, Chen Y, Zeng Z, Lei S
Bioengineered 2022 Apr;13(4):8643-8656
Bioengineered 2022 Apr;13(4):8643-8656
The long non-coding RNA T cell leukemia homeobox 1 neighbor enhances signal transducer and activator of transcription 5A phosphorylation to promote colon cancer cell invasion, migration, and metastasis.
Chen G, Lian D, Zhao L, Wang Z, Wuyun Q, Zhang N
Bioengineered 2022 Apr;13(4):11083-11095
Bioengineered 2022 Apr;13(4):11083-11095
Ginsenoside Rh4 Suppresses Metastasis of Gastric Cancer via SIX1-Dependent TGF-β/Smad2/3 Signaling Pathway.
Jiang H, Ma P, Duan Z, Liu Y, Shen S, Mi Y, Fan D
Nutrients 2022 Apr 9;14(8)
Nutrients 2022 Apr 9;14(8)
Mechanosensitive Piezo1 channels mediate renal fibrosis.
Zhao X, Kong Y, Liang B, Xu J, Lin Y, Zhou N, Li J, Jiang B, Cheng J, Li C, Wang W
JCI insight 2022 Apr 8;7(7)
JCI insight 2022 Apr 8;7(7)
TIM-1 promotes proliferation and metastasis, and inhibits apoptosis, in cervical cancer through the PI3K/AKT/p53 pathway.
Chen L, Qing J, Xiao Y, Huang X, Chi Y, Chen Z
BMC cancer 2022 Apr 7;22(1):370
BMC cancer 2022 Apr 7;22(1):370
Rhein Improves Renal Fibrosis by Restoring Cpt1a-Mediated Fatty Acid Oxidation through SirT1/STAT3/twist1 Pathway.
Song X, Du Z, Yao Z, Tang X, Zhang M
Molecules (Basel, Switzerland) 2022 Apr 6;27(7)
Molecules (Basel, Switzerland) 2022 Apr 6;27(7)
Biomimetic Nanomedicine-Triggered in Situ Vaccination for Innate and Adaptive Immunity Activations for Bacterial Osteomyelitis Treatment.
Lin H, Yang C, Luo Y, Ge M, Shen H, Zhang X, Shi J
ACS nano 2022 Apr 26;16(4):5943-5960
ACS nano 2022 Apr 26;16(4):5943-5960
Brusatol inhibits the growth of renal cell carcinoma by regulating the PTEN/PI3K/AKT pathway.
Wang T, Chen Z, Chen H, Yu X, Wang L, Liu X
Journal of ethnopharmacology 2022 Apr 24;288:115020
Journal of ethnopharmacology 2022 Apr 24;288:115020
ORP5 promotes tumor metastasis via stabilizing c-Met in renal cell carcinoma.
Song L, Zhang L, Zhou Y, Shao X, Xu Y, Pei D, Wang Q
Cell death discovery 2022 Apr 21;8(1):219
Cell death discovery 2022 Apr 21;8(1):219
Overexpression of GATA5 Inhibits Prostate Cancer Progression by Regulating PLAGL2 via the FAK/PI3K/AKT Pathway.
Wang Q, Liu Z, Zhai G, Yu X, Ke S, Shao H, Guo J
Cancers 2022 Apr 21;14(9)
Cancers 2022 Apr 21;14(9)
Epigenetic Deregulation of Protein Tyrosine Kinase 6 Promotes Carcinogenesis of Oral Squamous Cell Carcinoma.
Hsieh YP, Chen KC, Chen MY, Huang LY, Su AY, Chiang WF, Huang WT, Huang TT
International journal of molecular sciences 2022 Apr 19;23(9)
International journal of molecular sciences 2022 Apr 19;23(9)
METTL3-mediated m6A modification of STEAP2 mRNA inhibits papillary thyroid cancer progress by blocking the Hedgehog signaling pathway and epithelial-to-mesenchymal transition.
Zhu Y, Peng X, Zhou Q, Tan L, Zhang C, Lin S, Long M
Cell death & disease 2022 Apr 18;13(4):358
Cell death & disease 2022 Apr 18;13(4):358
Hexachlorophene, a selective SHP2 inhibitor, suppresses proliferation and metastasis of KRAS-mutant NSCLC cells by inhibiting RAS/MEK/ERK and PI3K/AKT signaling pathways.
Fu NJ, Xi RY, Shi XK, Li RZ, Zhang ZH, Li LY, Zhang GL, Wang F
Toxicology and applied pharmacology 2022 Apr 15;441:115988
Toxicology and applied pharmacology 2022 Apr 15;441:115988
Silencing of Nudix type 5 represses proliferation and invasion and enhances chemosensitivity of gastric carcinoma cells by affecting the AKT/GSK-3β/β-catenin pathway.
Tan D, Zhang Y
Toxicology and applied pharmacology 2022 Apr 15;441:115968
Toxicology and applied pharmacology 2022 Apr 15;441:115968
Quantum dots bind nanosheet to promote nanomaterial stability and resist endotoxin-induced fibrosis and PM(2.5)-induced pneumonia.
Zhou Q, Li D, Zhang S, Wang S, Hu X
Ecotoxicology and environmental safety 2022 Apr 1;234:113420
Ecotoxicology and environmental safety 2022 Apr 1;234:113420
m6A Modification-Mediated DUXAP8 Regulation of Malignant Phenotype and Chemotherapy Resistance of Hepatocellular Carcinoma Through miR-584-5p/MAPK1/ERK Pathway Axis.
Liu Z, Lu J, Fang H, Sheng J, Cui M, Yang Y, Tang B, Zhang X
Frontiers in cell and developmental biology 2021;9:783385
Frontiers in cell and developmental biology 2021;9:783385
Nxhl Controls Angiogenesis by Targeting VE-PTP Through Interaction With Nucleolin.
Luo H, Zhang Y, Deng Y, Li L, Sheng Z, Yu Y, Lin Y, Chen X, Feng P
Frontiers in cell and developmental biology 2021;9:728821
Frontiers in cell and developmental biology 2021;9:728821
PRDM16 Inhibits Cell Proliferation and Migration via Epithelial-to-Mesenchymal Transition by Directly Targeting Pyruvate Carboxylase in Papillary Thyroid Cancer.
Liu WL, Guan Q, Wen D, Ma B, Xu WB, Hu JQ, Wei WJ, Li DS, Wang Y, Xiang J, Liao T, Ji QH
Frontiers in cell and developmental biology 2021;9:723777
Frontiers in cell and developmental biology 2021;9:723777
Lack of IRF6 Disrupts Human Epithelial Homeostasis by Altering Colony Morphology, Migration Pattern, and Differentiation Potential of Keratinocytes.
Girousi E, Muerner L, Parisi L, Rihs S, von Gunten S, Katsaros C, Degen M
Frontiers in cell and developmental biology 2021;9:718066
Frontiers in cell and developmental biology 2021;9:718066
Cathelicidin-WA Protects Against LPS-Induced Gut Damage Through Enhancing Survival and Function of Intestinal Stem Cells.
Wang S, Kai L, Zhu L, Xu B, Chen N, Valencak TG, Wang Y, Shan T
Frontiers in cell and developmental biology 2021;9:685363
Frontiers in cell and developmental biology 2021;9:685363
Melatonin Attenuates Chromium (VI)-Induced Spermatogonial Stem Cell/Progenitor Mitophagy by Restoration of METTL3-Mediated RNA N(6)-Methyladenosine Modification.
Lv Y, Li T, Yang M, Su L, Zhu Z, Zhao S, Zeng W, Zheng Y
Frontiers in cell and developmental biology 2021;9:684398
Frontiers in cell and developmental biology 2021;9:684398
Artemisia argyi Essential Oil Inhibits Hepatocellular Carcinoma Metastasis via Suppression of DEPDC1 Dependent Wnt/β-Catenin Signaling Pathway.
Li Y, Tian Y, Zhong W, Wang N, Wang Y, Zhang Y, Zhang Z, Li J, Ma F, Zhao Z, Peng Y
Frontiers in cell and developmental biology 2021;9:664791
Frontiers in cell and developmental biology 2021;9:664791
LINC00511/miRNA-143-3p Modulates Apoptosis and Malignant Phenotype of Bladder Carcinoma Cells via PCMT1.
Dong LM, Zhang XL, Mao MH, Li YP, Zhang XY, Xue DW, Liu YL
Frontiers in cell and developmental biology 2021;9:650999
Frontiers in cell and developmental biology 2021;9:650999
Circular RNA circSIPA1L1 Contributes to Osteosarcoma Progression Through the miR-411-5p/RAB9A Signaling Pathway.
Xu Y, Yao T, Ni H, Zheng R, Huang K, Huang Y, Gao J, Qiao D, Shen S, Ma J
Frontiers in cell and developmental biology 2021;9:642605
Frontiers in cell and developmental biology 2021;9:642605
USP36-Mediated Deubiquitination of DOCK4 Contributes to the Diabetic Renal Tubular Epithelial Cell Injury via Wnt/β-Catenin Signaling Pathway.
Zhu S, Hou S, Lu Y, Sheng W, Cui Z, Dong T, Feng H, Wan Q
Frontiers in cell and developmental biology 2021;9:638477
Frontiers in cell and developmental biology 2021;9:638477
MicroRNA-15a Carried by Mesenchymal Stem Cell-Derived Extracellular Vesicles Inhibits the Immune Evasion of Colorectal Cancer Cells by Regulating the KDM4B/HOXC4/PD-L1 Axis.
Liu L, Yu T, Jin Y, Mai W, Zhou J, Zhao C
Frontiers in cell and developmental biology 2021;9:629893
Frontiers in cell and developmental biology 2021;9:629893
ENC1 Facilitates Colorectal Carcinoma Tumorigenesis and Metastasis via JAK2/STAT5/AKT Axis-Mediated Epithelial Mesenchymal Transition and Stemness.
Cui Y, Yang J, Bai Y, Li Q, Yao Y, Liu C, Wu F, Zhang J, Zhang Y
Frontiers in cell and developmental biology 2021;9:616887
Frontiers in cell and developmental biology 2021;9:616887
JMJD1A/NR4A1 Signaling Regulates the Procession of Renal Tubular Epithelial Interstitial Fibrosis Induced by AGEs in HK-2.
Wang S, Zuo A, Jiang W, Xie J, Lin H, Sun W, Zhao M, Xia J, Shao J, Zhao X, Liang D, Yang A, Sun J, Wang M
Frontiers in medicine 2021;8:807694
Frontiers in medicine 2021;8:807694
Comprehensive Analysis of the Potential Immune-Related Biomarker Transporter Associated With Antigen Processing 1 That Inhibits Metastasis and Invasion of Ovarian Cancer Cells.
Li X, Zeng S, Ding Y, Nie Y, Yang M
Frontiers in molecular biosciences 2021;8:763958
Frontiers in molecular biosciences 2021;8:763958
The Gut Microbiota Activates AhR Through the Tryptophan Metabolite Kyn to Mediate Renal Cell Carcinoma Metastasis.
Dai G, Chen X, He Y
Frontiers in nutrition 2021;8:712327
Frontiers in nutrition 2021;8:712327
Transcriptome Differences in Pig Tracheal Epithelial Cells in Response to Pasteurella Multocida Infection.
Wang X, Wang F, Lin L, Liang W, Liu S, Hua L, Wang X, Chen H, Peng Z, Wu B
Frontiers in veterinary science 2021;8:682514
Frontiers in veterinary science 2021;8:682514
MicroRNA-653-5p Promotes Gastric Cancer Proliferation and Metastasis by Targeting the SOCS6-STAT3 Pathway.
Li Z, Fan H, Chen W, Xiao J, Ma X, Ni P, Xu Z, Yang L
Frontiers in molecular biosciences 2021;8:655580
Frontiers in molecular biosciences 2021;8:655580
Acyl-CoA Thioesterase 7 is Transcriptionally Activated by Krüppel-Like Factor 13 and Promotes the Progression of Hepatocellular Carcinoma.
Xie X, Chen C, Feng S, Zuo S, Zhao X, Li H
Journal of hepatocellular carcinoma 2021;8:1623-1641
Journal of hepatocellular carcinoma 2021;8:1623-1641
Inositol Hexakisphosphate and Inositol Enhance the Inhibition of Colorectal Cancer Growth and Liver Metastasis by Capecitabine in a Mouse Model.
Li C, Ci Y, Liu X, Chen C, Liu C, Li X, Li Q, Song Y
Nutrition and cancer 2021;73(11-12):2306-2314
Nutrition and cancer 2021;73(11-12):2306-2314
KCNN4 promotes the progression of lung adenocarcinoma by activating the AKT and ERK signaling pathways.
Xu P, Mo X, Xia R, Jiang L, Zhang C, Xu H, Sun Q, Zhou G, Zhang Y, Wang Y, Xia H
Cancer biomarkers : section A of Disease markers 2021;31(2):187-201
Cancer biomarkers : section A of Disease markers 2021;31(2):187-201
Qingjie Fuzheng Granule Inhibits EMT and Induces Autophagy in Colorectal Cancer via mTOR Signaling Pathways.
Zhu X, Chen Y, Lin M, Huang B, Lin J
Evidence-based complementary and alternative medicine : eCAM 2021;2021:9950499
Evidence-based complementary and alternative medicine : eCAM 2021;2021:9950499
Human Tissue Kallikrein 1 Is Downregulated in Elderly Human Prostates and Possesses Potential In Vitro Antioxidative and Antifibrotic Effects in Rodent Prostates.
Zhang M, Luo C, Lin D, Cui K, Chen Z, Liu J
Oxidative medicine and cellular longevity 2021;2021:8877540
Oxidative medicine and cellular longevity 2021;2021:8877540
Network Pharmacology-Based Mechanistic Investigation of Jinshui Huanxian Formula Acting on Idiopathic Pulmonary Fibrosis.
Liu T, Xu P, Qi S, Ke S, Hu Q, Zhao P, Li J
Evidence-based complementary and alternative medicine : eCAM 2021;2021:8634705
Evidence-based complementary and alternative medicine : eCAM 2021;2021:8634705
PP2 Ameliorates Renal Fibrosis by Regulating the NF-κB/COX-2 and PPARγ/UCP2 Pathway in Diabetic Mice.
Wei J, Deng X, Li Y, Li R, Yang Z, Li X, Song S, Shi Y, Duan H, Wu H
Oxidative medicine and cellular longevity 2021;2021:7394344
Oxidative medicine and cellular longevity 2021;2021:7394344
General Control of Amino Acid Synthesis 5-Like 1-Mediated Acetylation of Manganese Superoxide Dismutase Regulates Oxidative Stress in Diabetic Kidney Disease.
Lv T, Lu Y, Liu Y, Feng H, Li C, Sheng W, Cui Z, Zhu S, Gu X, Yang Z, Wan Q
Oxidative medicine and cellular longevity 2021;2021:6691226
Oxidative medicine and cellular longevity 2021;2021:6691226
ARHGEF10L Promotes Cervical Tumorigenesis via RhoA-Mediated Signaling.
Tang J, Fang K, Li C, Chang X
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6683264
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6683264
Ginkgo Biloba Extract EGB761 Ameliorates the Extracellular Matrix Accumulation and Mesenchymal Transformation of Renal Tubules in Diabetic Kidney Disease by Inhibiting Endoplasmic Reticulum Stress.
Han J, Pang X, Shi X, Zhang Y, Peng Z, Xing Y
BioMed research international 2021;2021:6657206
BioMed research international 2021;2021:6657206
POU2F1 Promotes Cell Viability and Tumor Growth in Gastric Cancer through Transcriptional Activation of lncRNA TTC3-AS1.
Wang J, Xiao K, Hou F, Tang L, Luo D, Liu G, Wang Z
Journal of oncology 2021;2021:5570088
Journal of oncology 2021;2021:5570088
Therapeutic Potential of RTA 404 in Human Brain Malignant Glioma Cell Lines via Cell Cycle Arrest via p21/AKT Signaling.
Tsai TH, Lieu AS, Wang YW, Yang SF, Hsu YC, Lin CL
BioMed research international 2021;2021:5552226
BioMed research international 2021;2021:5552226
Release of HMGB1 in Podocytes Exacerbates Lipopolysaccharide-Induced Acute Kidney Injury.
Gao Z, Lu L, Chen X
Mediators of inflammation 2021;2021:5220226
Mediators of inflammation 2021;2021:5220226
Cysteine-Rich Intestinal Protein 1 Served as an Epithelial Ovarian Cancer Marker via Promoting Wnt/β-Catenin-Mediated EMT and Tumour Metastasis.
Liu Y, Li W, Luo J, Wu Y, Xu Y, Chen T, Zhang W, Fu F
Disease markers 2021;2021:3566749
Disease markers 2021;2021:3566749
Trefoil Factor 3 Inhibits Thyroid Cancer Cell Progression Related to IL-6/JAK/STAT3 Signaling Pathway.
Xin Y, Shang X, Sun X, Liu Y, Xu G, Xue G
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2130229
Evidence-based complementary and alternative medicine : eCAM 2021;2021:2130229
miR-149 Suppresses the Proliferation and Metastasis of Human Gastric Cancer Cells by Targeting FOXC1.
Li D, Zhang Y, Li Y, Wang X, Wang F, Du J, Zhang H, Shi H, Wang Y, Gao Y, Feng Y, Yan J, Xue Y, Yang Y, Zhang J
BioMed research international 2021;2021:1503403
BioMed research international 2021;2021:1503403
NSE, positively regulated by LINC00657-miR-93-5p axis, promotes small cell lung cancer (SCLC) invasion and epithelial-mesenchymal transition (EMT) process.
Lu L, Zha Z, Zhang P, Li D, Liu G
International journal of medical sciences 2021;18(16):3768-3779
International journal of medical sciences 2021;18(16):3768-3779
NEK2 plays an active role in Tumorigenesis and Tumor Microenvironment in Non-Small Cell Lung Cancer.
Bai R, Yuan C, Sun W, Zhang J, Luo Y, Gao Y, Li Y, Gong Y, Xie C
International journal of biological sciences 2021;17(8):1995-2008
International journal of biological sciences 2021;17(8):1995-2008
ITGB1 enhances the Radioresistance of human Non-small Cell Lung Cancer Cells by modulating the DNA damage response and YAP1-induced Epithelial-mesenchymal Transition.
Li Y, Sun C, Tan Y, Zhang H, Li Y, Zou H
International journal of biological sciences 2021;17(2):635-650
International journal of biological sciences 2021;17(2):635-650
Cyclovirobuxine inhibits the progression of clear cell renal cell carcinoma by suppressing the IGFBP3-AKT/STAT3/MAPK-Snail signalling pathway.
Liu Y, Lv H, Li X, Liu J, Chen S, Chen Y, Jin Y, An R, Yu S, Wang Z
International journal of biological sciences 2021;17(13):3522-3537
International journal of biological sciences 2021;17(13):3522-3537
Downregulation of m(6)A Reader YTHDC2 Promotes the Proliferation and Migration of Malignant Lung Cells via CYLD/NF-κB Pathway.
Wang J, Tan L, Jia B, Yu X, Yao R, OUYang N, Yu X, Cao X, Tong J, Chen T, Chen R, Li J
International journal of biological sciences 2021;17(10):2633-2651
International journal of biological sciences 2021;17(10):2633-2651
Hypoxia stimulates the migration and invasion of osteosarcoma via up-regulating the NUSAP1 expression.
Zhang L, Song J, Xin X, Sun D, Huang H, Chen Y, Zhang T, Zhang Y
Open medicine (Warsaw, Poland) 2021;16(1):1083-1089
Open medicine (Warsaw, Poland) 2021;16(1):1083-1089
Delivery of Rapamycin by Liposomes Synergistically Enhances the Chemotherapy Effect of 5-Fluorouracil on Colorectal Cancer.
Chen YQ, Zhu WT, Lin CY, Yuan ZW, Li ZH, Yan PK
International journal of nanomedicine 2021;16:269-281
International journal of nanomedicine 2021;16:269-281
Wogonin Alleviates Kidney Tubular Epithelial Injury in Diabetic Nephropathy by Inhibiting PI3K/Akt/NF-κB Signaling Pathways.
Lei L, Zhao J, Liu XQ, Chen J, Qi XM, Xia LL, Wu YG
Drug design, development and therapy 2021;15:3131-3150
Drug design, development and therapy 2021;15:3131-3150
SIRT6 inhibits metastasis by suppressing SNAIL expression in nasopharyngeal carcinoma cells.
Chen F, Ma X, Liu Y, Ma D, Gao X, Qian X
International journal of clinical and experimental pathology 2021;14(1):63-74
International journal of clinical and experimental pathology 2021;14(1):63-74
TEAD4 as a Prognostic Marker Promotes Cell Migration and Invasion of Urinary Bladder Cancer via EMT.
Huang Z, Yan Y, Tang P, Cai J, Cao X, Wang Z, Zhang F, Shen B
OncoTargets and therapy 2021;14:937-949
OncoTargets and therapy 2021;14:937-949
LncRNA UCID Promotes Hepatocellular Carcinoma Metastasis via Stabilization of Snail.
Yuan S, Si W, Zhuang K, Li Y, Zhang Y, Liu J, Yang L, Zhang X
OncoTargets and therapy 2021;14:725-736
OncoTargets and therapy 2021;14:725-736
XBP1s Acts as a Tumor Suppressor to Inhibit the EMT Process and Metastasis of Papillary Thyroid Cancer.
Yang W, Xu X, Xu M, Zhou J, Xi Z, Guo H, Ming J, Huang T
OncoTargets and therapy 2021;14:2339-2348
OncoTargets and therapy 2021;14:2339-2348
LncRNA IGFL2-AS1 Promotes the Proliferation, Migration, and Invasion of Colon Cancer Cells and is Associated with Patient Prognosis.
Cen X, Huang Y, Lu Z, Shao W, Zhuo C, Bao C, Feng S, Wei C, Tang X, Cen L, Guo W, Tian X, Tang Q, Huang X
Cancer management and research 2021;13:5957-5968
Cancer management and research 2021;13:5957-5968
Columbamine-Mediated PTEN/AKT Signal Pathway Regulates the Progression of Glioma.
Niu HT, Liu Y, Wang YZ, Tian Y, Yang M, Jiang HS
Cancer management and research 2021;13:489-497
Cancer management and research 2021;13:489-497
Normal Basal Epithelial Cells Stimulate the Migration and Invasion of Prostate Cancer Cell RM-1 by TGF-β1/STAT3 Axis in vitro.
Li CY, Chen CY, An JH, Wu JB, Shen H
Cancer management and research 2021;13:3685-3697
Cancer management and research 2021;13:3685-3697
GTW inhibits the Epithelial to Mesenchymal Transition of Epithelial Ovarian Cancer via ILK/AKT/GSK3β/Slug Signalling Pathway.
Feng Y, Le F, Tian P, Zhong Y, Zhan F, Huang G, Hu H, Chen T, Tan B
Journal of Cancer 2021;12(5):1386-1397
Journal of Cancer 2021;12(5):1386-1397
JMJD8 Promotes Malignant Progression of Lung Cancer by Maintaining EGFR Stability and EGFR/PI3K/AKT Pathway Activation.
Zhang B, Zhang Y, Jiang X, Su H, Wang Q, Wudu M, Jiang J, Ren H, Xu Y, Liu Z, Qiu X
Journal of Cancer 2021;12(4):976-987
Journal of Cancer 2021;12(4):976-987
Nogo-B receptor is required for stabilizing TGF-β type I receptor and promotes the TGF-β1-induced epithelial-to-mesenchymal transition of non-small cell lung cancer.
Wu D, Zhao B, Song Y, Chi X, Fu H, Guan T, Zhang L, Yang X, Hu K, Huang R, Jin X, Miao QR, Shao S
Journal of Cancer 2021;12(3):717-725
Journal of Cancer 2021;12(3):717-725
Linc01513 inhibits the malignant potential of Nasopharyngeal carcinoma by binding to PTBP1.
Wang J, Cai X, Zhang L, Lei D
Journal of Cancer 2021;12(24):7380-7389
Journal of Cancer 2021;12(24):7380-7389
Keratin 80 regulated by miR-206/ETS1 promotes tumor progression via the MEK/ERK pathway in ovarian cancer.
Liu O, Wang C, Wang S, Hu Y, Gou R, Dong H, Li S, Li X, Lin B
Journal of Cancer 2021;12(22):6835-6850
Journal of Cancer 2021;12(22):6835-6850
Shikonin suppresses the epithelial-to-mesenchymal transition by downregulating NHE1 in bladder cancer cells.
Mo L, Xu L, Jia M, Su B, Hu Y, Hu Z, Li H, Zhao C, Zhao Z, Li J
Journal of Cancer 2021;12(22):6814-6824
Journal of Cancer 2021;12(22):6814-6824
Dihydromyricetin Inhibits Tumor Growth and Epithelial-Mesenchymal Transition through regulating miR-455-3p in Cholangiocarcinoma.
Li X, Yang ZS, Cai WW, Deng Y, Chen L, Tan SL
Journal of Cancer 2021;12(20):6058-6070
Journal of Cancer 2021;12(20):6058-6070
SNX-2112 Induces Apoptosis and Inhibits Proliferation, Invasion, and Migration of Non-Small Cell Lung Cancer by Downregulating Epithelial-Mesenchymal Transition via the Wnt/β-Catenin Signaling Pathway.
Cheng X, Qin L, Deng L, Zhu X, Li Y, Wu X, Zheng Y
Journal of Cancer 2021;12(19):5825-5837
Journal of Cancer 2021;12(19):5825-5837
Demethylzelasteral inhibits proliferation and EMT via repressing Wnt/β-catenin signaling in esophageal squamous cell carcinoma.
Yu J, Wang W, Liu B, Gu J, Chen S, Cui Y, Sun G
Journal of Cancer 2021;12(13):3967-3975
Journal of Cancer 2021;12(13):3967-3975
Dextran Sulfate Effects EMT of Human Gastric Cancer Cells by Reducing HIF-1α/ TGF-β.
Huang YN, Xu YY, Ma Q, Li MQ, Guo JX, Wang X, Jin X, Shang J, Jiao LX
Journal of Cancer 2021;12(11):3367-3377
Journal of Cancer 2021;12(11):3367-3377
NKCC1 promotes proliferation, invasion and migration in human gastric cancer cells via activation of the MAPK-JNK/EMT signaling pathway.
Wang JF, Zhao K, Chen YY, Qiu Y, Zhu JH, Li BP, Wang Z, Chen JQ
Journal of Cancer 2021;12(1):253-263
Journal of Cancer 2021;12(1):253-263
Hypoxia-Induced miR-378a-3p Inhibits Osteosarcoma Invasion and Epithelial-to-Mesenchymal Transition via BYSL Regulation.
Zhang J, Tang H, Jiang X, Huang N, Wei Q
Frontiers in genetics 2021;12:804952
Frontiers in genetics 2021;12:804952
The Protective Effects of Zornia diphylla (L.) Pers. Against Acute Liver Injury Induced by Carbon Tetrachloride in Mice.
Xie SZ, Zhai XY, Xi SY, Qiu YK, Zhang YM, Kong XJ, Li YH, Zhu L, Wang Z, Zhang SG, Huang SQ, Lu DW, Wang Z
Frontiers in pharmacology 2021;12:764282
Frontiers in pharmacology 2021;12:764282
The ALDH Family Contributes to Immunocyte Infiltration, Proliferation and Epithelial-Mesenchymal Transformation in Glioma.
Wang Z, Mo Y, Tan Y, Wen Z, Dai Z, Zhang H, Zhang X, Feng S, Liang X, Song T, Cheng Q
Frontiers in immunology 2021;12:756606
Frontiers in immunology 2021;12:756606
Transcriptome-Based Network Analysis Reveals Hirudin Potentiates Anti-Renal Fibrosis Efficacy in UUO Rats.
Yu HX, Lin W, Yang K, Wei LJ, Chen JL, Liu XY, Zhong K, Chen X, Pei M, Yang HT
Frontiers in pharmacology 2021;12:741801
Frontiers in pharmacology 2021;12:741801
Taxus wallichiana var. chinensis (Pilg.) Florin Aqueous Extract Suppresses the Proliferation and Metastasis in Lung Carcinoma via JAK/STAT3 Signaling Pathway.
Sun L, Ding S, Luo Q, Wang P, Yang X, Wu L, Chen Y, Zheng X, Zhang H, Yuan L, Ruan S, Xie C
Frontiers in pharmacology 2021;12:736442
Frontiers in pharmacology 2021;12:736442
CXCL5 Downregulation in Villous Tissue Is Correlated With Recurrent Spontaneous Abortion.
Zhang S, Ding J, Wang J, Yin T, Zhang Y, Yang J
Frontiers in immunology 2021;12:717483
Frontiers in immunology 2021;12:717483
Decreased USP2a Expression Inhibits Trophoblast Invasion and Associates With Recurrent Miscarriage.
Wang J, Ding J, Zhang S, Chen X, Yan S, Zhang Y, Yin T
Frontiers in immunology 2021;12:717370
Frontiers in immunology 2021;12:717370
Mefunidone Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice.
Han Y, Jiang M, He R, Lv X, Liao X, He Y, Zhang F, Long L, Jiang G, Peng Z, Tao L, Hu G, Meng J
Frontiers in pharmacology 2021;12:713572
Frontiers in pharmacology 2021;12:713572
Oxymatrine Synergistically Enhances Doxorubicin Anticancer Effects in Colorectal Cancer.
Pan D, Zhang W, Zhang N, Xu Y, Chen Y, Peng J, Chen Y, Zhang Y, Shen X
Frontiers in pharmacology 2021;12:673432
Frontiers in pharmacology 2021;12:673432
AGR3 Regulates Airway Epithelial Junctions in Patients with Frequent Exacerbations of COPD.
Ye R, Wang C, Sun P, Bai S, Zhao L
Frontiers in pharmacology 2021;12:669403
Frontiers in pharmacology 2021;12:669403
Autophagic Inhibition of Caveolin-1 by Compound Phyllanthus urinaria L. Activates Ubiquitination and Proteasome Degradation of β-catenin to Suppress Metastasis of Hepatitis B-Associated Hepatocellular Carcinoma.
Huang D, Yang B, Yao Y, Liao M, Zhang Y, Zeng Y, Zhang F, Wang N, Tong G
Frontiers in pharmacology 2021;12:659325
Frontiers in pharmacology 2021;12:659325
PLAU Promotes Cell Proliferation and Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma.
Chen G, Sun J, Xie M, Yu S, Tang Q, Chen L
Frontiers in genetics 2021;12:651882
Frontiers in genetics 2021;12:651882
Pharmacologic Targeting of BET Proteins Attenuates Hyperuricemic Nephropathy in Rats.
Xiong C, Deng J, Wang X, Shao X, Zhou Q, Zou H, Zhuang S
Frontiers in pharmacology 2021;12:636154
Frontiers in pharmacology 2021;12:636154
COE Inhibits Vasculogenic Mimicry by Targeting EphA2 in Hepatocellular Carcinoma, a Research Based on Proteomics Analysis.
Chu Z, Shi X, Chen G, He X, Qian Y, Wang H, Tao L, Liu Y, Jiang W, Chen J
Frontiers in pharmacology 2021;12:619732
Frontiers in pharmacology 2021;12:619732
XMD-17-51 Inhibits DCLK1 Kinase and Prevents Lung Cancer Progression.
Yang WQ, Zhao WJ, Zhu LL, Xu SJ, Zhang XL, Liang Y, Ding XF, Kiselyov A, Chen G
Frontiers in pharmacology 2021;12:603453
Frontiers in pharmacology 2021;12:603453
N6-methyladenosine-induced circ1662 promotes metastasis of colorectal cancer by accelerating YAP1 nuclear localization.
Chen C, Yuan W, Zhou Q, Shao B, Guo Y, Wang W, Yang S, Guo Y, Zhao L, Dang Q, Yang X, Wang G, Kang Q, Ji Z, Liu J, Sun Z
Theranostics 2021;11(9):4298-4315
Theranostics 2021;11(9):4298-4315
3'untranslated regions (3'UTR) of Gelsolin mRNA displays anticancer effects in non-small cell lung cancer (NSCLC) cells.
Liu X, Huang X, Ma J, Li L, Hu H, Feng J, Gao X, Zhang Y, Liu L
American journal of cancer research 2021;11(8):3857-3876
American journal of cancer research 2021;11(8):3857-3876
BCAT1 knockdown-mediated suppression of melanoma cell proliferation and migration is associated with reduced oxidative phosphorylation.
Zhang B, Xu F, Wang K, Liu M, Li J, Zhao Q, Jiang L, Zhang Z, Li Y, Chen H, Zhang J, Tang X, Zhang J
American journal of cancer research 2021;11(6):2670-2683
American journal of cancer research 2021;11(6):2670-2683
Necroptosis pathway blockage attenuates PFKFB3 inhibitor-induced cell viability loss and genome instability in colorectal cancer cells.
Yan S, Li Q, Zhang D, Wang X, Xu Y, Zhang C, Guo D, Bao Y
American journal of cancer research 2021;11(5):2062-2080
American journal of cancer research 2021;11(5):2062-2080
P4HA1 as an unfavorable prognostic marker promotes cell migration and invasion of glioblastoma via inducing EMT process under hypoxia microenvironment.
Zhu X, Liu S, Yang X, Wang W, Shao W, Ji T
American journal of cancer research 2021;11(2):590-617
American journal of cancer research 2021;11(2):590-617
Extracellular vesicles derived from M1 macrophages deliver miR-146a-5p and miR-146b-5p to suppress trophoblast migration and invasion by targeting TRAF6 in recurrent spontaneous abortion.
Ding J, Zhang Y, Cai X, Zhang Y, Yan S, Wang J, Zhang S, Yin T, Yang C, Yang J
Theranostics 2021;11(12):5813-5830
Theranostics 2021;11(12):5813-5830
Epigenetically silenced linc00261 contributes to the metastasis of hepatocellular carcinoma via inducing the deficiency of FOXA2 transcription.
Chen Z, Xiang L, Hu Z, Ou H, Liu X, Yu L, Chen W, Jiang L, Yu Q, Fang Y, Xu Y, Liu Q, Huang Y, Li X, Yang D
American journal of cancer research 2021;11(1):277-296
American journal of cancer research 2021;11(1):277-296
Long Non-Coding RNA CCAT2 Activates RAB14 and Acts as an Oncogene in Colorectal Cancer.
Wang D, Li Z, Yin H
Frontiers in oncology 2021;11:751903
Frontiers in oncology 2021;11:751903
Honokiol Suppresses Perineural Invasion of Pancreatic Cancer by Inhibiting SMAD2/3 Signaling.
Qin T, Li J, Xiao Y, Wang X, Gong M, Wang Q, Zhu Z, Zhang S, Zhang W, Cao F, Han L, Wang Z, Ma Q, Sha H
Frontiers in oncology 2021;11:728583
Frontiers in oncology 2021;11:728583
YBX1 Enhances Metastasis and Stemness by Transcriptionally Regulating MUC1 in Lung Adenocarcinoma.
Xie Q, Zhao S, Liu W, Cui Y, Li F, Li Z, Guo T, Yu W, Guo W, Deng W, Gu C
Frontiers in oncology 2021;11:702491
Frontiers in oncology 2021;11:702491
Photobiomodulation With Blue Laser Inhibits Bladder Cancer Progression.
Xia Y, Yu W, Cheng F, Rao T, Ruan Y, Yuan R, Ning J, Zhou X, Lin F, Zheng D
Frontiers in oncology 2021;11:701122
Frontiers in oncology 2021;11:701122
TRIM50 Suppresses Pancreatic Cancer Progression and Reverses the Epithelial-Mesenchymal Transition via Facilitating the Ubiquitous Degradation of Snail1.
Li R, Zhu L, Peng Y, Zhang X, Dai C, Liu D
Frontiers in oncology 2021;11:695740
Frontiers in oncology 2021;11:695740
PGK1 Is a Key Target for Anti-Glycolytic Therapy of Ovarian Cancer: Based on the Comprehensive Analysis of Glycolysis-Related Genes.
Gou R, Hu Y, Liu O, Dong H, Gao L, Wang S, Zheng M, Li X, Lin B
Frontiers in oncology 2021;11:682461
Frontiers in oncology 2021;11:682461
The lncRNA ADAMTS9-AS2 Regulates RPL22 to Modulate TNBC Progression via Controlling the TGF-β Signaling Pathway.
Ni K, Huang Z, Zhu Y, Xue D, Jin Q, Zhang C, Gu C
Frontiers in oncology 2021;11:654472
Frontiers in oncology 2021;11:654472
Cucurbitacin B Inhibits Cell Proliferation by Regulating X-Inactive Specific Transcript Expression in Tongue Cancer.
Tao B, Wang D, Yang S, Liu Y, Wu H, Li Z, Chang L, Yang Z, Liu W
Frontiers in oncology 2021;11:651648
Frontiers in oncology 2021;11:651648
Chrysin Induced Cell Apoptosis Through H19/let-7a/COPB2 Axis in Gastric Cancer Cells and Inhibited Tumor Growth.
Chen L, Li Q, Jiang Z, Li C, Hu H, Wang T, Gao Y, Wang D
Frontiers in oncology 2021;11:651644
Frontiers in oncology 2021;11:651644
Long Non-Coding RNA LINC00467 Correlates to Poor Prognosis and Aggressiveness of Breast Cancer.
Zhang Y, Sun Y, Ding L, Shi W, Ding K, Zhu Y
Frontiers in oncology 2021;11:643394
Frontiers in oncology 2021;11:643394
A Novel c-MET-Targeting Antibody-Drug Conjugate for Pancreatic Cancer.
Jin Y, Zhang Z, Zou S, Li F, Chen H, Peng C, Deng X, Wen C, Shen B, Zhan Q
Frontiers in oncology 2021;11:634881
Frontiers in oncology 2021;11:634881
Derivation and Validation of a Prognostic Model for Cancer Dependency Genes Based on CRISPR-Cas9 in Gastric Adenocarcinoma.
Zhou W, Li J, Lu X, Liu F, An T, Xiao X, Kuo ZC, Wu W, He Y
Frontiers in oncology 2021;11:617289
Frontiers in oncology 2021;11:617289
miR-139-5p Loss-Mediated WTAP Activation Contributes to Hepatocellular Carcinoma Progression by Promoting the Epithelial to Mesenchymal Transition.
Liu W, Gao X, Chen X, Zhao N, Sun Y, Zou Y, Guan Y, Yang L, Pei X, Wang G, Wang B, Li M, Song W
Frontiers in oncology 2021;11:611544
Frontiers in oncology 2021;11:611544
Epigallocatechin-3-gallate inhibits proliferation and triggers apoptosis in colon cancer via the hedgehog/phosphoinositide 3-kinase pathways.
Ding F, Yang S
Canadian journal of physiology and pharmacology 2021 Sep;99(9):910-920
Canadian journal of physiology and pharmacology 2021 Sep;99(9):910-920
Aiduqing formula suppresses breast cancer metastasis via inhibiting CXCL1-mediated autophagy.
Yang B, Peng F, Zhang Y, Wang X, Wang S, Zheng Y, Zhang J, Zeng Y, Wang N, Peng C, Wang Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep;90:153628
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Sep;90:153628
Homoharringtonine inhibits the progression of hepatocellular carcinoma by suppressing the PI3K/AKT/GSK3β/Slug signaling pathway.
Liu HY, Dong TX, Li ZZ, Li TT, Jiang J, Zhu MW, An TT, Chen YD, Yang XH
Neoplasma 2021 Sep;68(5):924-937
Neoplasma 2021 Sep;68(5):924-937
Long non-coding RNA DUXAP9 promotes hepatocellular carcinoma cell stemness via directly interacting with sox9.
Zeng R, Wang C, Wang W, Wang S
Environmental toxicology 2021 Sep;36(9):1793-1801
Environmental toxicology 2021 Sep;36(9):1793-1801
Demethylzeylasteral inhibits proliferation, migration, and invasion through FBXW7/c-Myc axis in gastric cancer.
Li Y, Su Y, Zhao Y, Hu X, Zhao G, He J, Wan S, Lü M, Cui H
MedComm 2021 Sep;2(3):467-480
MedComm 2021 Sep;2(3):467-480
CDC20 promotes bone formation via APC/C dependent ubiquitination and degradation of p65.
Du Y, Zhang M, Liu X, Li Z, Hu M, Tian Y, Lv L, Zhang X, Liu Y, Zhang P, Zhou Y
EMBO reports 2021 Sep 6;22(9):e52576
EMBO reports 2021 Sep 6;22(9):e52576
Identification of abnormally high expression of POGZ as a new biomarker associated with a poor prognosis in osteosarcoma.
Zheng S, Liu Y, Sun H, Jia J, Wu T, Ding R, Cheng X
European journal of histochemistry : EJH 2021 Sep 3;65(3)
European journal of histochemistry : EJH 2021 Sep 3;65(3)
The antioxidant N-acetylcysteine promotes immune response and inhibits epithelial-mesenchymal transition to alleviate pulmonary fibrosis in chronic obstructive pulmonary disease by suppressing the VWF/p38 MAPK axis.
Zhu L, Xu F, Kang X, Zhou J, Yao Q, Lin Y, Zhang W
Molecular medicine (Cambridge, Mass.) 2021 Sep 3;27(1):97
Molecular medicine (Cambridge, Mass.) 2021 Sep 3;27(1):97
PHLDA3 exerts an antitumor function in prostate cancer by down-regulating Wnt/β-catenin pathway via inhibition of Akt.
Ma S, Quan P, Yu C, Fan X, Yang S, Jia W, Zhang L, Wang F, Liu F, Yang L, Qin W, Yang X
Biochemical and biophysical research communications 2021 Sep 24;571:66-73
Biochemical and biophysical research communications 2021 Sep 24;571:66-73
Reversible reprogramming of cardiomyocytes to a fetal state drives heart regeneration in mice.
Chen Y, Lüttmann FF, Schoger E, Schöler HR, Zelarayán LC, Kim KP, Haigh JJ, Kim J, Braun T
Science (New York, N.Y.) 2021 Sep 24;373(6562):1537-1540
Science (New York, N.Y.) 2021 Sep 24;373(6562):1537-1540
KLK8 promotes the proliferation and metastasis of colorectal cancer via the activation of EMT associated with PAR1.
Hua Q, Sun Z, Liu Y, Shen X, Zhao W, Zhu X, Xu P
Cell death & disease 2021 Sep 22;12(10):860
Cell death & disease 2021 Sep 22;12(10):860
MiR-613 inhibits the proliferation, migration, and invasion of papillary thyroid carcinoma cells by directly targeting TAGLN2.
Huang Y, Zhang H, Wang L, Liu C, Guo M, Tan H, Liu Z
Cancer cell international 2021 Sep 16;21(1):494
Cancer cell international 2021 Sep 16;21(1):494
Circular RNA ZNF609 enhances proliferation and glycolysis during glioma progression by miR-378b/SLC2A1 axis.
Zhao Z, Li G, Han Y, Li Y, Ji Z, Guo R, Yu X
Aging 2021 Sep 14;13(17):21122-21133
Aging 2021 Sep 14;13(17):21122-21133
TNFSF9 promotes metastasis of pancreatic cancer through Wnt/Snail signaling and M2 polarization of macrophages.
Wu J, Wang Y, Yang Y, Liu F, Chen J, Jiang Z, Jiang Z
Aging 2021 Sep 13;13(17):21571-21586
Aging 2021 Sep 13;13(17):21571-21586
Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer.
Shah VV, Duncan AD, Jiang S, Stratton SA, Allton KL, Yam C, Jain A, Krause PM, Lu Y, Cai S, Tu Y, Zhou X, Zhang X, Jiang Y, Carroll CL, Kang Z, Liu B, Shen J, Gagea M, Manu SM, Huo L, Gilcrease M, Powell RT, Guo L, Stephan C, Davies PJ, Parker-Thornburg J, Lozano G, Behringer RR, Piwnica-Worms H, Chang JT, Moulder SL, Barton MC
Nature communications 2021 Sep 10;12(1):5389
Nature communications 2021 Sep 10;12(1):5389
Oleanolic acid inhibits the migration and invasion of hepatocellular carcinoma cells by promoting microRNA-122 expression.
He Y, Liu X, Huang M, Wei Z, Zhang M, He M, Zheng Z, Dong H, Liu D
Die Pharmazie 2021 Sep 1;76(9):422-427
Die Pharmazie 2021 Sep 1;76(9):422-427
MIER3 induces epithelial-mesenchymal transition and promotes breast cancer cell aggressiveness via forming a co-repressor complex with HDAC1/HDAC2/Snail.
Huang W, Chen J, Liu X, Liu X, Duan S, Chen L, Liu X, Lan J, Zou Y, Guo D, Zhou J
Experimental cell research 2021 Sep 1;406(1):112722
Experimental cell research 2021 Sep 1;406(1):112722
Iguratimod decreases bleomycin-induced pulmonary fibrosis in association with inhibition of TNF-α in mice.
Shao S, Qu Z, Liang Y, Xu Y, Zhou D, Li D, Zhang Y, Yin S
International immunopharmacology 2021 Oct;99:107936
International immunopharmacology 2021 Oct;99:107936
Effects of andrographolide on renal tubulointersticial injury and fibrosis. Evidence of its mechanism of action.
Liu W, Liang L, Zhang Q, Li Y, Yan S, Tang T, Ren Y, Mo J, Liu F, Chen X, Lan T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct;91:153650
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Oct;91:153650
Generation of Urine-Derived Induced Pluripotent Stem Cell Line from Patients with Acute Kidney Injury.
Jin Y, Zhang M, Li M, Zhang H, Zhang F, Zhang H, Yin Z, Zhou M, Wan X, Li R, Cao C
Cellular reprogramming 2021 Oct;23(5):290-303
Cellular reprogramming 2021 Oct;23(5):290-303
Upregulation of microfibrillar-associated protein 2 is closely associated with tumor angiogenesis and poor prognosis in hepatocellular carcinoma.
Zhang N, Shao F, Jia W
Oncology letters 2021 Oct;22(4):739
Oncology letters 2021 Oct;22(4):739
Dihydroartemisinin suppresses proliferation, migration, the Wnt/β-catenin pathway and EMT via TNKS in gastric cancer.
Ma Y, Zhang P, Zhang Q, Wang X, Miao Q, Lyu X, Cui B, Ma H
Oncology letters 2021 Oct;22(4):688
Oncology letters 2021 Oct;22(4):688
Advanced Maternal Age-associated SIRT1 Deficiency Compromises Trophoblast Epithelial-Mesenchymal Transition through an Increase in Vimentin Acetylation.
Xiong L, Ye X, Chen Z, Fu H, Li S, Xu P, Yu J, Wen L, Gao R, Fu Y, Qi H, Kilby MD, Saffery R, Baker PN, Tong C
Aging cell 2021 Oct;20(10):e13491
Aging cell 2021 Oct;20(10):e13491
Transcription factor POU4F2 promotes colorectal cancer cell migration and invasion through hedgehog-mediated epithelial-mesenchymal transition.
Guo K, Wang P, Zhang L, Zhou Y, Dai X, Yan Y, Chen Y, Wasan HS, Yu J, Ruan S, Sun L
Cancer science 2021 Oct;112(10):4176-4186
Cancer science 2021 Oct;112(10):4176-4186
CDC42EP3 is a key promoter involved in the development and progression of gastric cancer.
Chen W, Zhu Y, Zhang W, Zhang H, Zhou Y, Sun P, Wu G
Carcinogenesis 2021 Oct 5;42(9):1179-1188
Carcinogenesis 2021 Oct 5;42(9):1179-1188
PFP@PLGA/Cu(12)Sb(4)S(13)-mediated PTT ablates hepatocellular carcinoma by inhibiting the RAS/MAPK/MT-CO1 signaling pathway.
Dong T, Jiang J, Zhang H, Liu H, Zou X, Niu J, Mao Y, Zhu M, Chen X, Li Z, Chen Y, Shi C, Yang X
Nano convergence 2021 Oct 4;8(1):29
Nano convergence 2021 Oct 4;8(1):29
AnnexinA7 promotes epithelial-mesenchymal transition by interacting with Sorcin and contributes to aggressiveness in hepatocellular carcinoma.
Ling F, Zhang H, Sun Y, Meng J, Sanches JGP, Huang H, Zhang Q, Yu X, Wang B, Hou L, Zhang J
Cell death & disease 2021 Oct 29;12(11):1018
Cell death & disease 2021 Oct 29;12(11):1018
UM-6 induces autophagy and apoptosis via the Hippo-YAP signaling pathway in cervical cancer.
Wang D, He J, Dong J, Wu S, Liu S, Zhu H, Xu T
Cancer letters 2021 Oct 28;519:2-19
Cancer letters 2021 Oct 28;519:2-19
ZEB1 represses biogenesis of circ-DOCK5 to facilitate metastasis in esophageal squamous cell carcinoma via a positive feedback loop with TGF-β.
Meng L, Zheng Y, Liu S, Ju Y, Ren S, Sang Y, Zhu Y, Gu L, Liu F, Zhao Y, Zhang X, Sang M
Cancer letters 2021 Oct 28;519:117-129
Cancer letters 2021 Oct 28;519:117-129
Improved epithelial cell-cell adhesion using molecular mobility of supramolecular surfaces.
Mikami R, Arisaka Y, Hakariya M, Iwata T, Yui N
Biomaterials science 2021 Oct 26;9(21):7151-7158
Biomaterials science 2021 Oct 26;9(21):7151-7158
Identification of novel key genes associated with the metastasis of prostate cancer based on bioinformatics prediction and validation.
Song F, Zhang Y, Pan Z, Hu X, Yi Y, Zheng X, Wei H, Huang P
Cancer cell international 2021 Oct 25;21(1):559
Cancer cell international 2021 Oct 25;21(1):559
NOV/CCN3 Promotes Cell Migration and Invasion in Intrahepatic Cholangiocarcinoma via miR-92a-3p.
Liang T, Shen L, Ji Y, Jia L, Dou Y, Guo L
Genes 2021 Oct 21;12(11)
Genes 2021 Oct 21;12(11)
Upregulation of CPNE7 in mesenchymal stromal cells promotes oral squamous cell carcinoma metastasis through the NF-κB pathway.
Ji X, Sun T, Xie S, Qian H, Song L, Wang L, Liu H, Feng Q
Cell death discovery 2021 Oct 14;7(1):294
Cell death discovery 2021 Oct 14;7(1):294
MYH9 is crucial for stem cell-like properties in non-small cell lung cancer by activating mTOR signaling.
Chen M, Sun LX, Yu L, Liu J, Sun LC, Yang ZH, Shu X, Ran YL
Cell death discovery 2021 Oct 11;7(1):282
Cell death discovery 2021 Oct 11;7(1):282
Overexpression of DTL enhances cell motility and promotes tumor metastasis in cervical adenocarcinoma by inducing RAC1-JNK-FOXO1 axis.
Liu S, Gu L, Wu N, Song J, Yan J, Yang S, Feng Y, Wang Z, Wang L, Zhang Y, Jin Y
Cell death & disease 2021 Oct 11;12(10):929
Cell death & disease 2021 Oct 11;12(10):929
NOTCH2NLA silencing inhibits ovarian carcinoma progression and oncogenic activity in vivo and in vitro.
Guo W, Sun Z, Zhao N, Zhou Y, Ren J, Huang L, Ping Y
Annals of translational medicine 2021 Nov;9(22):1669
Annals of translational medicine 2021 Nov;9(22):1669
Hsa_circ_0001326 regulates proliferation, migration, invasion, and EMT of HTR-8/SVneo cells via increasing IL16 expression.
Liu Y, Ma X, Liu Y
American journal of reproductive immunology (New York, N.Y. : 1989) 2021 Nov;86(5):e13484
American journal of reproductive immunology (New York, N.Y. : 1989) 2021 Nov;86(5):e13484
P-element Induced WImpy protein-like RNA-mediated gene silencing 2 regulates tumor cell progression, apoptosis, and metastasis in oral squamous cell carcinoma.
Zhou S, Yang S, Li F, Hou J, Chang H
The Journal of international medical research 2021 Nov;49(11):3000605211053158
The Journal of international medical research 2021 Nov;49(11):3000605211053158
Abnormally elevated ubiquilin‑1 expression in breast cancer regulates metastasis and stemness via AKT signaling.
Feng X, Cao A, Qin T, Zhang Q, Fan S, Wang B, Song B, Yu X, Li L
Oncology reports 2021 Nov;46(5)
Oncology reports 2021 Nov;46(5)
Silencing ACTG1 Expression Induces Prostate Cancer Epithelial Mesenchymal Transition Through MAPK/ERK Signaling Pathway.
Xiao L, Peng H, Yan M, Chen S
DNA and cell biology 2021 Nov;40(11):1445-1455
DNA and cell biology 2021 Nov;40(11):1445-1455
SC66 inhibits the proliferation and induces apoptosis of human bladder cancer cells by targeting the AKT/β-catenin pathway.
Chen W, Zhao S, Yu W, Rao T, Ruan Y, Zhu S, Xia Y, Song H, Cheng F
Journal of cellular and molecular medicine 2021 Nov;25(22):10684-10697
Journal of cellular and molecular medicine 2021 Nov;25(22):10684-10697
O-GlcNAcylation promotes the migratory ability of hepatocellular carcinoma cells via regulating FOXA2 stability and transcriptional activity.
Huang H, Wu Q, Guo X, Huang T, Xie X, Wang L, Liu Y, Shi L, Li W, Zhang J, Liu Y
Journal of cellular physiology 2021 Nov;236(11):7491-7503
Journal of cellular physiology 2021 Nov;236(11):7491-7503
Blood glucose control contributes to protein stability of Ski-related novel protein N in a rat model of diabetes.
Liang L, Li S, Liu H, Mao Y, Liu L, Zhang X, Peng W, Xiao Y, Zhang F, Shi M, Wang Y, Guo B
Experimental and therapeutic medicine 2021 Nov;22(5):1341
Experimental and therapeutic medicine 2021 Nov;22(5):1341
Tspan5 promotes epithelial-mesenchymal transition and tumour metastasis of hepatocellular carcinoma by activating Notch signalling.
Xie Q, Guo H, He P, Deng H, Gao Y, Dong N, Niu W, Liu T, Li M, Wang S, Wu Y, Li JL
Molecular oncology 2021 Nov;15(11):3184-3202
Molecular oncology 2021 Nov;15(11):3184-3202
HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma.
Tian T, Hong F, Wang Z, Hu J, Chen N, Lv L, Yi Q
Cell death discovery 2021 Nov 8;7(1):341
Cell death discovery 2021 Nov 8;7(1):341
Si-Wu-Tang ameliorates fibrotic liver injury via modulating intestinal microbiota and bile acid homeostasis.
Xue X, Wu J, Ding M, Gao F, Zhou F, Xu B, Lu M, Li J, Li X
Chinese medicine 2021 Nov 4;16(1):112
Chinese medicine 2021 Nov 4;16(1):112
Fisetin inhibits the proliferation, migration and invasion of pancreatic cancer by targeting PI3K/AKT/mTOR signaling.
Xiao Y, Liu Y, Gao Z, Li X, Weng M, Shi C, Wang C, Sun L
Aging 2021 Nov 25;13(22):24753-24767
Aging 2021 Nov 25;13(22):24753-24767
miR-30b-5p inhibits proliferation, invasion, and migration of papillary thyroid cancer by targeting GALNT7 via the EGFR/PI3K/AKT pathway.
Wang Y, Wang C, Fu Z, Zhang S, Chen J
Cancer cell international 2021 Nov 24;21(1):618
Cancer cell international 2021 Nov 24;21(1):618
HMMR is a downstream target of FOXM1 in enhancing proliferation and partial epithelial-to-mesenchymal transition of bladder cancer cells.
Yang D, Ma Y, Zhao P, Ma J, He C
Experimental cell research 2021 Nov 15;408(2):112860
Experimental cell research 2021 Nov 15;408(2):112860
Drug-containing serum of rhubarb-astragalus capsule inhibits the epithelial-mesenchymal transformation of HK-2 by downregulating TGF-β1/p38MAPK/Smad2/3 pathway.
Qin MY, Huang SQ, Zou XQ, Zhong XB, Yang YF, Zhang YT, Mi ZC, Zhang YS, Huang ZG
Journal of ethnopharmacology 2021 Nov 15;280:114414
Journal of ethnopharmacology 2021 Nov 15;280:114414
Single-Cell Analyses Reveal Mechanisms of Cancer Stem Cell Maintenance and Epithelial-Mesenchymal Transition in Recurrent Bladder Cancer.
Wang H, Mei Y, Luo C, Huang Q, Wang Z, Lu GM, Qin L, Sun Z, Huang CW, Yang ZW, Chen J, Yin W, Qian CN, Zeng J, Chen L, Leng Q, Guo Y, Jia G
Clinical cancer research : an official journal of the American Association for Cancer Research 2021 Nov 15;27(22):6265-6278
Clinical cancer research : an official journal of the American Association for Cancer Research 2021 Nov 15;27(22):6265-6278
Deletion of miR-15a inhibited glioma development via targeting Smad7 and inhibiting EMT pathway.
Guo Y, Gao X, An S, Li X, Pan L, Liu H, Liu J, Gao J, Zhao Z, Li G, Han Y, Li Y, Ji Z
Aging 2021 Nov 11;13(21):24339-24348
Aging 2021 Nov 11;13(21):24339-24348
AICAR enhances the cytotoxicity of PFKFB3 inhibitor in an AMPK signaling-independent manner in colorectal cancer cells.
Yan S, Yuan D, Li Q, Li S, Zhang F
Medical oncology (Northwood, London, England) 2021 Nov 10;39(1):10
Medical oncology (Northwood, London, England) 2021 Nov 10;39(1):10
SAA1 is transcriptionally activated by STAT3 and accelerates renal interstitial fibrosis by inducing endoplasmic reticulum stress.
Zhang F, Zhou X, Zou H, Liu L, Li X, Ruan Y, Xie Y, Shi M, Xiao Y, Wang Y, Zhou Y, Wu Y, Guo B
Experimental cell research 2021 Nov 1;408(1):112856
Experimental cell research 2021 Nov 1;408(1):112856
Long non‑coding RNA MIR4713HG aggravates malignant behaviors in oral tongue squamous cell carcinoma via binding with microRNA let‑7c‑5p.
Jia B, Zheng X, Qiu X, Jiang X, Liu J, Huang Z, Xiang S, Chen G, Zhao J
International journal of molecular medicine 2021 May;47(5)
International journal of molecular medicine 2021 May;47(5)
miR-509-3p Suppresses Migration, Invasion, and Epithelial- Mesenchymal Transition in Melanoma Cells by Targeting Collagen Triple Helix Repeat Containing 1.
Yuan K, Sun Y, Ji Y
Balkan medical journal 2021 May;38(3):177-182
Balkan medical journal 2021 May;38(3):177-182
Stress-induced phosphoprotein 1 facilitates breast cancer cell progression and indicates poor prognosis for breast cancer patients.
Lin L, Wen J, Lin B, Xia E, Zheng C, Ye L, Wang Y, Wang O, Chen Y
Human cell 2021 May;34(3):901-917
Human cell 2021 May;34(3):901-917
Exosomal microRNA-301a-3p promotes the proliferation and invasion of nasopharyngeal carcinoma cells by targeting BTG1 mRNA.
Cheng Q, Li Q, Xu L, Jiang H
Molecular medicine reports 2021 May;23(5)
Molecular medicine reports 2021 May;23(5)
The clinical significance, prognostic value and biological role of lncRNA LINC01793 in oral squamous cell carcinoma.
Yuan SJ, Li SY, Wang YH, Zhang HF, Hua Y, Wang T
Archives of oral biology 2021 May;125:105105
Archives of oral biology 2021 May;125:105105
Tubule-specific protein nanocages potentiate targeted renal fibrosis therapy.
Zhang X, Chen Q, Zhang L, Zheng H, Lin C, Yang Q, Liu T, Zhang H, Chen X, Ren L, Shan W
Journal of nanobiotechnology 2021 May 26;19(1):156
Journal of nanobiotechnology 2021 May 26;19(1):156
Ginsenoside CK Inhibits Hypoxia-Induced Epithelial-Mesenchymal Transformation through the HIF-1α/NF-κB Feedback Pathway in Hepatocellular Carcinoma.
Zhang J, Ma X, Fan D
Foods (Basel, Switzerland) 2021 May 26;10(6)
Foods (Basel, Switzerland) 2021 May 26;10(6)
STIP1 knockdown suppresses colorectal cancer cell proliferation, migration and invasion by inhibiting STAT3 pathway.
Xia Y, Chen J, Liu G, Huang W, Wei X, Wei Z, He Y
Chemico-biological interactions 2021 May 25;341:109446
Chemico-biological interactions 2021 May 25;341:109446
The miR-378c-Samd1 circuit promotes phenotypic modulation of vascular smooth muscle cells and foam cells formation in atherosclerosis lesions.
Tian S, Cao Y, Wang J, Bi Y, Zhong J, Meng X, Sun W, Yang R, Gan L, Wang X, Li H, Wang R
Scientific reports 2021 May 18;11(1):10548
Scientific reports 2021 May 18;11(1):10548
Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice.
Harn HI, Wang SP, Lai YC, Van Handel B, Liang YC, Tsai S, Schiessl IM, Sarkar A, Xi H, Hughes M, Kaemmer S, Tang MJ, Peti-Peterdi J, Pyle AD, Woolley TE, Evseenko D, Jiang TX, Chuong CM
Nature communications 2021 May 10;12(1):2595
Nature communications 2021 May 10;12(1):2595
A HIF1A/miR-485-5p/SRPK1 axis modulates the aggressiveness of glioma cells upon hypoxia.
Cheng L, Peng R, Guo P, Zhang H, Liu D, Liao X, Liu Y, Mo X, Liao Y
Experimental cell research 2021 May 1;402(1):112547
Experimental cell research 2021 May 1;402(1):112547
Trim47 overexpression correlates with poor prognosis in gastric cancer.
Xia Y, Wei Z, Huang W, Wei X, He Y
Neoplasma 2021 Mar;68(2):307-316
Neoplasma 2021 Mar;68(2):307-316
Moderate oxidative stress promotes epithelial-mesenchymal transition in the lens epithelial cells via the TGF-β/Smad and Wnt/β-catenin pathways.
Chen X, Yan H, Chen Y, Li G, Bin Y, Zhou X
Molecular and cellular biochemistry 2021 Mar;476(3):1631-1642
Molecular and cellular biochemistry 2021 Mar;476(3):1631-1642
Abnormal cGMP-dependent protein kinase I-mediated decidualization in preeclampsia.
Chen J, Ren W, Lin L, Zeng S, Huang L, Tang J, Bi S, Pan J, Chen D, Du L
Hypertension research : official journal of the Japanese Society of Hypertension 2021 Mar;44(3):318-324
Hypertension research : official journal of the Japanese Society of Hypertension 2021 Mar;44(3):318-324
MiR-520a-3p inhibits malignant progression of epithelial ovarian cancer by targeting SUV39H1 expression.
Li J, Shao W, Zhao J
Human cell 2021 Mar;34(2):570-578
Human cell 2021 Mar;34(2):570-578
Aptamer-SH2 superbinder-based targeted therapy for pancreatic ductal adenocarcinoma.
Liu AD, Zhou J, Bi XY, Hou GQ, Li SS, Chen Q, Xu H, Cao X
Clinical and translational medicine 2021 Mar;11(3):e337
Clinical and translational medicine 2021 Mar;11(3):e337
HN1 promotes tumor growth and metastasis of anaplastic thyroid carcinoma by interacting with STMN1.
Pan Z, Fang Q, Li L, Zhang Y, Xu T, Liu Y, Zheng X, Tan Z, Huang P, Ge M
Cancer letters 2021 Mar 31;501:31-42
Cancer letters 2021 Mar 31;501:31-42
A 2-Benzylmalonate Derivative as STAT3 Inhibitor Suppresses Tumor Growth in Hepatocellular Carcinoma by Upregulating β-TrCP E3 Ubiquitin Ligase.
Peng T, Wonganan O, Zhang Z, Yu J, Xi R, Cao Y, Suksamrarn A, Zhang G, Wang F
International journal of molecular sciences 2021 Mar 25;22(7)
International journal of molecular sciences 2021 Mar 25;22(7)
Sesquiterpene Lactone Deoxyelephantopin Isolated from Elephantopus scaber and Its Derivative DETD-35 Suppress BRAF(V600E) Mutant Melanoma Lung Metastasis in Mice.
Cvetanova B, Li MY, Yang CC, Hsiao PW, Yang YC, Feng JH, Shen YC, Nakagawa-Goto K, Lee KH, Shyur LF
International journal of molecular sciences 2021 Mar 22;22(6)
International journal of molecular sciences 2021 Mar 22;22(6)
Anti-Fibrosis Effects of Magnesium Lithospermate B in Experimental Pulmonary Fibrosis: By Inhibiting TGF-βRI/Smad Signaling.
Luo X, Deng Q, Xue Y, Zhang T, Wu Z, Peng H, Xuan L, Pan G
Molecules (Basel, Switzerland) 2021 Mar 19;26(6)
Molecules (Basel, Switzerland) 2021 Mar 19;26(6)
The MIR155 host gene/microRNA-627/HMGB1/NF-κB loop modulates fibroblast proliferation and extracellular matrix deposition.
Li J, Zhang X, Wang T, Li J, Su Q, Zhong C, Chen Z, Liang Y
Life sciences 2021 Mar 15;269:119085
Life sciences 2021 Mar 15;269:119085
Upregulation of bromodomain PHD finger transcription factor in ovarian cancer and its critical role for cancer cell proliferation and survival.
Miao J, Zhang M, Huang X, Xu L, Tang R, Wang H, Han S
Biochemistry and cell biology = Biochimie et biologie cellulaire 2021 Jun;99(3):304-312
Biochemistry and cell biology = Biochimie et biologie cellulaire 2021 Jun;99(3):304-312
Suberoylanilide Hydroxamic Acid (SAHA) Reduces Fibrosis Markers and Deactivates Human Stellate Cells via the Epithelial-Mesenchymal Transition (EMT).
Özel M, Baskol M, Akalın H, Baskol G
Cell biochemistry and biophysics 2021 Jun;79(2):349-357
Cell biochemistry and biophysics 2021 Jun;79(2):349-357
Runx2 deficiency in junctional epithelium of mouse molars decreases the expressions of E-cadherin and junctional adhesion molecule 1.
Tian Y, Mu H, Wang A, Gao Y, Dong Z, Zhao Y, Li C, Zhang L, Gao Y
Journal of molecular histology 2021 Jun;52(3):545-553
Journal of molecular histology 2021 Jun;52(3):545-553
Long non‑coding RNA MIR4435‑2HG promotes the progression of head and neck squamous cell carcinoma by regulating the miR‑383‑5p/RBM3 axis.
Wang S, Chen X, Qiao T
Oncology reports 2021 Jun;45(6)
Oncology reports 2021 Jun;45(6)
Effects of CDKN2B-AS1 on cellular proliferation, invasion and AKT3 expression are attenuated by miR-424-5p in a model of ovarian endometriosis.
Wang S, Yi M, Zhang X, Zhang T, Jiang L, Cao L, Zhou Y, Fang X
Reproductive biomedicine online 2021 Jun;42(6):1057-1066
Reproductive biomedicine online 2021 Jun;42(6):1057-1066
Fructose-1,6-bisphosphatase aggravates oxidative stress-induced apoptosis in asthma by suppressing the Nrf2 pathway.
Hu J, Wang J, Li C, Shang Y
Journal of cellular and molecular medicine 2021 Jun;25(11):5001-5014
Journal of cellular and molecular medicine 2021 Jun;25(11):5001-5014
SEC61G is upregulated and required for tumor progression in human kidney cancer.
Meng H, Jiang X, Wang J, Sang Z, Guo L, Yin G, Wang Y
Molecular medicine reports 2021 Jun;23(6)
Molecular medicine reports 2021 Jun;23(6)
MicroRNA-133a-3p suppresses malignant behavior of non-small cell lung cancer cells by negatively regulating ERBB2.
Xu Y, Zhang L, Xia L, Zhu X
Oncology letters 2021 Jun;21(6):457
Oncology letters 2021 Jun;21(6):457
LEM domain containing 1 promotes thyroid cancer cell proliferation and migration by activating the Wnt/β-catenin signaling pathway and epithelial-mesenchymal transition.
Xu M, Lin B, Zheng D, Wen J, Hu W, Li C, Zhang X, Zhang X, Qu J
Oncology letters 2021 Jun;21(6):442
Oncology letters 2021 Jun;21(6):442
Downregulation of ARMC8 promotes tumorigenesis through activating Wnt/β-catenin pathway and EMT in cutaneous squamous cell carcinomas.
Li X, Zhang C, Yuan Y, Wang Y, Lu S, Zhou Z, Zhen P, Zhou M
Journal of dermatological science 2021 Jun;102(3):184-192
Journal of dermatological science 2021 Jun;102(3):184-192
YWHAE as an HE4 interacting protein can influence the malignant behaviour of ovarian cancer by regulating the PI3K/AKT and MAPK pathways.
Li X, Wang C, Wang S, Hu Y, Jin S, Liu O, Gou R, Nie X, Liu J, Lin B
Cancer cell international 2021 Jun 9;21(1):302
Cancer cell international 2021 Jun 9;21(1):302
LncRNA Bmp1 promotes the healing of intestinal mucosal lesions via the miR-128-3p/PHF6/PI3K/AKT pathway.
Zhuang M, Deng Y, Zhang W, Zhu B, Yan H, Lou J, Zhang P, Cui Q, Tang H, Sun H, Sun Y
Cell death & disease 2021 Jun 9;12(6):595
Cell death & disease 2021 Jun 9;12(6):595
NLRP3 induces the autocrine secretion of IL-1β to promote epithelial-mesenchymal transition and metastasis in breast cancer.
Wang Y, Zhang H, Xu Y, Peng T, Meng X, Zou F
Biochemical and biophysical research communications 2021 Jun 30;560:72-79
Biochemical and biophysical research communications 2021 Jun 30;560:72-79
LncRNA MONC suppresses the malignant phenotype of Endometrial Cancer Stem Cells and Endometrial Carcinoma Cells by regulating the MiR-636/GLCE axis.
Li Y, Huo J, He J, Ma X
Cancer cell international 2021 Jun 30;21(1):331
Cancer cell international 2021 Jun 30;21(1):331
STAT3/HIF-1α signaling activation mediates peritoneal fibrosis induced by high glucose.
Yang X, Bao M, Fang Y, Yu X, Ji J, Ding X
Journal of translational medicine 2021 Jun 30;19(1):283
Journal of translational medicine 2021 Jun 30;19(1):283
MicroRNA-139 inhibits pancreatic-cancer carcinogenesis by suppressing RalB via the Ral/RAC/PI3K pathway.
Wang Y, Zheng Y, Chen Q, Dai Y, Li T
Archives of biochemistry and biophysics 2021 Jun 15;704:108719
Archives of biochemistry and biophysics 2021 Jun 15;704:108719
Small extracellular ring domain is necessary for CD82/KAI1'anti-metastasis function.
Ma X, He X, Wang C, Huang X, Li Y, Ma K
Biochemical and biophysical research communications 2021 Jun 11;557:110-116
Biochemical and biophysical research communications 2021 Jun 11;557:110-116
Identification of a Novel TAR RNA-Binding Protein 2 Modulator with Potential Therapeutic Activity against Hepatocellular Carcinoma.
Zhou Z, Li Y, Ma X, Cao B, Peng T, Sheng Y, Peng H, Li R, Cao Y, Xi R, Li F, Wang M, Sun H, Zhang G, Zhang H, Hu K, Xiao W, Wang F
Journal of medicinal chemistry 2021 Jun 10;64(11):7404-7421
Journal of medicinal chemistry 2021 Jun 10;64(11):7404-7421
VEGF/Src signaling mediated pleural barrier damage and increased permeability contributes to subpleural pulmonary fibrosis.
Lu YZ, Liang LM, Cheng PP, Xiong L, Wang M, Song LJ, Yu F, He XL, Xiong L, Wang XR, Xin JB, Ye H, Ma WL
American journal of physiology. Lung cellular and molecular physiology 2021 Jun 1;320(6):L990-L1004
American journal of physiology. Lung cellular and molecular physiology 2021 Jun 1;320(6):L990-L1004
Neutrophil extracellular traps promote gastric cancer metastasis by inducing epithelial‑mesenchymal transition.
Zhu T, Zou X, Yang C, Li L, Wang B, Li R, Li H, Xu Z, Huang D, Wu Q
International journal of molecular medicine 2021 Jul;48(1)
International journal of molecular medicine 2021 Jul;48(1)
MDM2 induces EMT via the B‑Raf signaling pathway through 14‑3‑3.
Ou M, Xu X, Chen Y, Li L, Zhang L, Liao Y, Sun W, Quach C, Feng J, Tang L
Oncology reports 2021 Jul;46(1)
Oncology reports 2021 Jul;46(1)
CXCL6 fuels the growth and metastases of esophageal squamous cell carcinoma cells both in vitro and in vivo through upregulation of PD-L1 via activation of STAT3 pathway.
Zheng S, Shen T, Liu Q, Liu T, Tuerxun A, Zhang Q, Yang L, Han X, Lu X
Journal of cellular physiology 2021 Jul;236(7):5373-5386
Journal of cellular physiology 2021 Jul;236(7):5373-5386
Regulatory effect of microRNA-223-3p on breast cancer cell processes via the Hippo/Yap signaling pathway.
Du T, Wang D, Wan X, Xu J, Xiao Q, Liu B
Oncology letters 2021 Jul;22(1):516
Oncology letters 2021 Jul;22(1):516
miR-665 inhibits epithelial-to-mesenchymal transition in bladder cancer via the SMAD3/SNAIL axis.
Wang W, Ying Y, Xie H, Li J, Ma X, He L, Xu M, Chen S, Shen H, Zheng X, Liu B, Wang X, Xie L
Cell cycle (Georgetown, Tex.) 2021 Jul;20(13):1242-1252
Cell cycle (Georgetown, Tex.) 2021 Jul;20(13):1242-1252
LncRNA SGMS1-AS1 regulates lung adenocarcinoma cell proliferation, migration, invasion, and EMT progression via miR-106a-5p/MYLI9 axis.
Liu T, Yang C, Wang W, Liu C
Thoracic cancer 2021 Jul;12(14):2104-2112
Thoracic cancer 2021 Jul;12(14):2104-2112
The oncogenic role of the cerebral endothelial cell adhesion molecule (CERCAM) in bladder cancer cells in vitro and in vivo.
Zuo Y, Xu X, Chen M, Qi L
Cancer medicine 2021 Jul;10(13):4437-4450
Cancer medicine 2021 Jul;10(13):4437-4450
CHN1 promotes epithelial-mesenchymal transition via the Akt/GSK-3β/Snail pathway in cervical carcinoma.
Zhao H, Wang L, Wang S, Chen X, Liang M, Zhang X, Wang J, Xu X
Journal of translational medicine 2021 Jul 8;19(1):295
Journal of translational medicine 2021 Jul 8;19(1):295
A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein.
Li P, Cao S, Huang Y, Zhang Y, Liu J, Cai X, Zhou L, Li J, Jiang Z, Ding L, Zheng Z, Li S, Ye Q
Cell death discovery 2021 Jul 29;7(1):198
Cell death discovery 2021 Jul 29;7(1):198
LRRC19 Promotes Permeability of the Gut Epithelial Barrier Through Degrading PKC-ζ and PKCι/λ to Reduce Expression of ZO1, ZO3, and Occludin.
Su X, Wei J, Qi H, Jin M, Zhang Q, Zhang Y, Zhang C, Yang R
Inflammatory bowel diseases 2021 Jul 27;27(8):1302-1315
Inflammatory bowel diseases 2021 Jul 27;27(8):1302-1315
A mesenchymal-like subpopulation in non-neuroendocrine SCLC contributes to metastasis.
Jin Y, Xiao T, Feng Y, Yang J, Guo C, Hu L, Ji H
Journal of genetics and genomics = Yi chuan xue bao 2021 Jul 20;48(7):571-581
Journal of genetics and genomics = Yi chuan xue bao 2021 Jul 20;48(7):571-581
Circular RNA circ_001422 promotes the progression and metastasis of osteosarcoma via the miR-195-5p/FGF2/PI3K/Akt axis.
Yang B, Li L, Tong G, Zeng Z, Tan J, Su Z, Liu Z, Lin J, Gao W, Chen J, Zeng S, Wu G, Li L, Zhu S, Liu Q, Lin L
Journal of experimental & clinical cancer research : CR 2021 Jul 16;40(1):235
Journal of experimental & clinical cancer research : CR 2021 Jul 16;40(1):235
LncRNA PCGEM1 induces proliferation and migration in non-small cell lung cancer cells through modulating the miR-590-3p/SOX11 axis.
Wen H, Feng H, Ma Q, Liang C
BMC pulmonary medicine 2021 Jul 14;21(1):234
BMC pulmonary medicine 2021 Jul 14;21(1):234
Mitochondrial creatine kinase 1 in non-small cell lung cancer progression and hypoxia adaptation.
Li M, Liu H, Li J, Guo S, Lv Y
Respiratory research 2021 Jul 1;22(1):190
Respiratory research 2021 Jul 1;22(1):190
Fangchinoline exerts antitumour activity by suppressing the EGFR‑PI3K/AKT signalling pathway in colon adenocarcinoma.
Jiang F, Ren S, Chen Y, Zhang A, Zhu Y, Zhang Z, Li Z, Piao D
Oncology reports 2021 Jan;45(1):139-150
Oncology reports 2021 Jan;45(1):139-150
MSH6 Aggravates the Hypoxic Microenvironment via Regulating HIF1A to Promote the Metastasis of Glioblastoma Multiforme.
Shi Y, Jiang J, Cui Y, Chen Y, Dong T, An H, Liu P
DNA and cell biology 2021 Jan;40(1):93-100
DNA and cell biology 2021 Jan;40(1):93-100
Long noncoding RNA EPB41L4A-AS1 functions as an oncogene by regulating the Rho/ROCK pathway in colorectal cancer.
Bin J, Nie S, Tang Z, Kang A, Fu Z, Hu Y, Liao Q, Xiong W, Zhou Y, Tang Y, Jiang J
Journal of cellular physiology 2021 Jan;236(1):523-535
Journal of cellular physiology 2021 Jan;236(1):523-535
Laminin‑332 mediates proliferation, apoptosis, invasion, migration and epithelial‑to‑mesenchymal transition in pancreatic ductal adenocarcinoma.
Huang C, Chen J
Molecular medicine reports 2021 Jan;23(1)
Molecular medicine reports 2021 Jan;23(1)
CD147 deficiency in T cells prevents thymic involution by inhibiting the EMT process in TECs in the presence of TGFβ.
Chen R, Wang K, Feng Z, Zhang MY, Wu J, Geng JJ, Chen ZN
Cellular & molecular immunology 2021 Jan;18(1):171-181
Cellular & molecular immunology 2021 Jan;18(1):171-181
Triptolidenol, isolated from Tripterygium wilfordii, disrupted NF-κB/COX-2 pathway by targeting ATP-binding sites of IKKβ in clear cell renal cell carcinoma.
Jin J, Zhou M, Wang X, Liu M, Huang H, Yan F, Yu Z, Shu X, Huo X, Feng L, Zhang B, Huang S, Deng S, Wang C, Ma X
Fitoterapia 2021 Jan;148:104779
Fitoterapia 2021 Jan;148:104779
Lidocaine inhibits the metastatic potential of ovarian cancer by blocking Na(V) 1.5-mediated EMT and FAK/Paxillin signaling pathway.
Liu C, Yu M, Li Y, Wang H, Xu C, Zhang X, Li M, Guo H, Ma D, Guo X
Cancer medicine 2021 Jan;10(1):337-349
Cancer medicine 2021 Jan;10(1):337-349
Triple co-culture and perfusion bioreactor for studying the interaction between Neisseria gonorrhoeae and neutrophils: A novel 3D tissue model for bacterial infection and immunity.
Heydarian M, Schweinlin M, Schwarz T, Rawal R, Walles H, Metzger M, Rudel T, Kozjak-Pavlovic V
Journal of tissue engineering 2021 Jan-Dec;12:2041731420988802
Journal of tissue engineering 2021 Jan-Dec;12:2041731420988802
Obacunone Attenuates Liver Fibrosis with Enhancing Anti-Oxidant Effects of GPx-4 and Inhibition of EMT.
Bai Y, Wang W, Wang L, Ma L, Zhai D, Wang F, Shi R, Liu C, Xu Q, Chen G, Lu Z
Molecules (Basel, Switzerland) 2021 Jan 9;26(2)
Molecules (Basel, Switzerland) 2021 Jan 9;26(2)
The long intergenic noncoding RNA GAS5 reduces cisplatin-resistance in non-small cell lung cancer through the miR-217/LHPP axis.
Yang X, Meng L, Zhong Y, Hu F, Wang L, Wang M
Aging 2021 Jan 8;13(2):2864-2884
Aging 2021 Jan 8;13(2):2864-2884
miR-335-5p suppresses gastric cancer progression by targeting MAPK10.
Gao Y, Wang Y, Wang X, Zhao C, Wang F, Du J, Zhang H, Shi H, Feng Y, Li D, Yan J, Yao Y, Hu W, Ding R, Zhang M, Wang L, Huang C, Zhang J
Cancer cell international 2021 Jan 22;21(1):71
Cancer cell international 2021 Jan 22;21(1):71
Overexpression of NCAPG inhibits cardia adenocarcinoma apoptosis and promotes epithelial-mesenchymal transition through the Wnt/β-catenin signaling pathway.
Zhang X, Zhu M, Wang H, Song Z, Zhan D, Cao W, Han Y, Jia J
Gene 2021 Jan 15;766:145163
Gene 2021 Jan 15;766:145163
Circ_0001438 participates in the pathogenesis of preeclampsia via the circ_0001438/miR-942/NLRP3 regulatory network.
Li X, Yang R, Xu Y, Zhang Y
Placenta 2021 Jan 15;104:40-50
Placenta 2021 Jan 15;104:40-50
A "dual-guide" bioinspired drug delivery strategy of a macrophage-based carrier against postoperative triple-negative breast cancer recurrence.
Qiu Y, Ren K, Zhao W, Yu Q, Guo R, He J, Mei L, Liu Y, Tang J, Xu S, Li J, Wei J, Li M, Zhang Z, He Q
Journal of controlled release : official journal of the Controlled Release Society 2021 Jan 10;329:191-204
Journal of controlled release : official journal of the Controlled Release Society 2021 Jan 10;329:191-204
Berberine inhibits intestinal epithelial barrier dysfunction in colon caused by peritoneal dialysis fluid by improving cell migration.
Zhang D, Jiang L, Wang M, Jin M, Zhang X, Liu D, Wang Z, Yang L, Xu X
Journal of ethnopharmacology 2021 Jan 10;264:113206
Journal of ethnopharmacology 2021 Jan 10;264:113206
Tumor-associated macrophages promote pancreatic ductal adenocarcinoma progression by inducing epithelial-to-mesenchymal transition.
Xiong C, Zhu Y, Xue M, Jiang Y, Zhong Y, Jiang L, Shi M, Chen H
Aging 2021 Jan 10;13(3):3386-3404
Aging 2021 Jan 10;13(3):3386-3404
PGRN(-/-) TAMs-derived exosomes inhibit breast cancer cell invasion and migration and its mechanism exploration.
Yue S, Ye X, Zhou T, Gan D, Qian H, Fang W, Yao M, Zhang D, Shi H, Chen T
Life sciences 2021 Jan 1;264:118687
Life sciences 2021 Jan 1;264:118687
SLC6A8 is involved in the progression of non-small cell lung cancer through the Notch signaling pathway.
Feng Y, Guo X, Tang H
Annals of translational medicine 2021 Feb;9(3):264
Annals of translational medicine 2021 Feb;9(3):264
The interaction between lipocalin 2 and dipyridine ketone hydrazone dithiocarbamte may influence respective function in proliferation and metastasis-related gene expressions in HepG2 cell.
Li C, Li Y, Lou L, Han X, Wang H, Huang T, Li C
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2021 Feb;26(1):123-133
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2021 Feb;26(1):123-133
Piezo type mechanosensitive ion channel component 1 facilitates gastric cancer omentum metastasis.
Wang X, Cheng G, Miao Y, Qiu F, Bai L, Gao Z, Huang Y, Dong L, Niu X, Wang X, Li Y, Tang H, Xu Y, Song X
Journal of cellular and molecular medicine 2021 Feb;25(4):2238-2253
Journal of cellular and molecular medicine 2021 Feb;25(4):2238-2253
M2 macrophage-derived G-CSF promotes trophoblasts EMT, invasion and migration via activating PI3K/Akt/Erk1/2 pathway to mediate normal pregnancy.
Ding J, Yang C, Zhang Y, Wang J, Zhang S, Guo D, Yin T, Yang J
Journal of cellular and molecular medicine 2021 Feb;25(4):2136-2147
Journal of cellular and molecular medicine 2021 Feb;25(4):2136-2147
Involvement of miR-27a-3p in diabetic nephropathy via affecting renal fibrosis, mitochondrial dysfunction, and endoplasmic reticulum stress.
Wu L, Wang Q, Guo F, Ma X, Wang J, Zhao Y, Yan Y, Qin G
Journal of cellular physiology 2021 Feb;236(2):1454-1468
Journal of cellular physiology 2021 Feb;236(2):1454-1468
USP1-WDR48 deubiquitinase complex enhances TGF-β induced epithelial-mesenchymal transition of TNBC cells via stabilizing TAK1.
Han D, Wang L, Chen B, Zhao W, Liang Y, Li Y, Zhang H, Liu Y, Wang X, Chen T, Li C, Song X, Luo D, Li Z, Yang Q
Cell cycle (Georgetown, Tex.) 2021 Feb;20(3):320-331
Cell cycle (Georgetown, Tex.) 2021 Feb;20(3):320-331
Triptolide inhibits epithelial-mesenchymal transition phenotype through the p70S6k/GSK3/β-catenin signaling pathway in taxol-resistant human lung adenocarcinoma.
Tian Y, Li P, Xiao Z, Zhou J, Xue X, Jiang N, Peng C, Wu L, Tian H, Popper H, Poh ME, Marcucci F, Zhang C, Zhao X
Translational lung cancer research 2021 Feb;10(2):1007-1019
Translational lung cancer research 2021 Feb;10(2):1007-1019
Transcription of MRPL12 regulated by Nrf2 contributes to the mitochondrial dysfunction in diabetic kidney disease.
Gu X, Liu Y, Wang N, Zhen J, Zhang B, Hou S, Cui Z, Wan Q, Feng H
Free radical biology & medicine 2021 Feb 20;164:329-340
Free radical biology & medicine 2021 Feb 20;164:329-340
Role of SIK1 in the transition of acute kidney injury into chronic kidney disease.
Hu J, Qiao J, Yu Q, Liu B, Zhen J, Liu Y, Ma Q, Li Y, Wang Q, Wang C, Lv Z
Journal of translational medicine 2021 Feb 15;19(1):69
Journal of translational medicine 2021 Feb 15;19(1):69
RECQL4 regulates DNA damage response and redox homeostasis in esophageal cancer.
Lyu G, Su P, Hao X, Chen S, Ren S, Zhao Z, Gong Y, Liu Q, Shao C
Cancer biology & medicine 2021 Feb 15;18(1):120-138
Cancer biology & medicine 2021 Feb 15;18(1):120-138
DUOX2 promotes the progression of colorectal cancer cells by regulating the AKT pathway and interacting with RPL3.
Zhang X, Han J, Feng L, Zhi L, Jiang D, Yu B, Zhang Z, Gao B, Zhang C, Li M, Zhao L, Wang G
Carcinogenesis 2021 Feb 11;42(1):105-117
Carcinogenesis 2021 Feb 11;42(1):105-117
GABARAP suppresses EMT and breast cancer progression via the AKT/mTOR signaling pathway.
Liu Y, Wang D, Lei M, Gao J, Cui Y, Jin X, Yu Q, Jiang Y, Guo Y, Liu Y, Cai L, Chen X
Aging 2021 Feb 11;13(4):5858-5874
Aging 2021 Feb 11;13(4):5858-5874
High expression of vinculin predicts poor prognosis and distant metastasis and associates with influencing tumor-associated NK cell infiltration and epithelial-mesenchymal transition in gastric cancer.
Li H, Wang C, Lan L, Behrens A, Tomaschko M, Ruiz J, Su Q, Zhao G, Yuan C, Xiao X, Li B, Yan L, Wu W, Li W, Chen J, He Y, Zhang C
Aging 2021 Feb 1;13(4):5197-5225
Aging 2021 Feb 1;13(4):5197-5225
Compound Kushen Injection intervenes metabolic reprogramming and epithelial-mesenchymal transition of HCC via regulating β-catenin/c-Myc signaling.
Wang KX, Du GH, Qin XM, Gao L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Dec;93:153781
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Dec;93:153781
Long non-coding RNA AC122108.1 promotes lung adenocarcinoma brain metastasis and progression through the Wnt/β-catenin pathway by directly binding to aldolase A.
Feng S, Liu H, Du P, Dong X, Pang Q, Guo H
Annals of translational medicine 2021 Dec;9(23):1729
Annals of translational medicine 2021 Dec;9(23):1729
PDGF-BB promotes vascular smooth muscle cell migration by enhancing Pim-1 expression via inhibiting miR-214.
Zhou J, Shao L, Yu J, Huang J, Feng Q
Annals of translational medicine 2021 Dec;9(23):1728
Annals of translational medicine 2021 Dec;9(23):1728
IFIT1 modulates the proliferation, migration and invasion of pancreatic cancer cells via Wnt/β-catenin signaling.
Li TH, Zhao BB, Qin C, Wang YY, Li ZR, Cao HT, Yang XY, Zhou XT, Wang WB
Cellular oncology (Dordrecht, Netherlands) 2021 Dec;44(6):1425-1437
Cellular oncology (Dordrecht, Netherlands) 2021 Dec;44(6):1425-1437
Evaluation of autofluorescence visualization system in the delineation of oral squamous cell carcinoma surgical margins.
Sun LF, Wang CX, Cao ZY, Han W, Guo SS, Wang YZ, Meng Y, Hou CX, Zhu QH, Tang YT, Li HQ, Zhang T, Ye JH
Photodiagnosis and photodynamic therapy 2021 Dec;36:102487
Photodiagnosis and photodynamic therapy 2021 Dec;36:102487
BAIAP2L2 promotes the proliferation, migration and invasion of osteosarcoma associated with the Wnt/β-catenin pathway.
Guo H, Peng J, Hu J, Chang S, Liu H, Luo H, Chen X, Tang H, Chen Y
Journal of bone oncology 2021 Dec;31:100393
Journal of bone oncology 2021 Dec;31:100393
Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial-mesenchymal plasticity of human peritoneal mesothelial cells.
Gao L, Nie X, Gou R, Hu Y, Dong H, Li X, Lin B
Journal of cellular and molecular medicine 2021 Dec;25(23):10916-10929
Journal of cellular and molecular medicine 2021 Dec;25(23):10916-10929
TRIP4 transcriptionally activates DDIT4 and subsequent mTOR signaling to promote glioma progression.
Li W, Hu S, Tian C, Wan X, Yu W, Guo P, Zhao F, Hua C, Lu X, Xue G, Han S, Guo W, Wang D, Deng W
Free radical biology & medicine 2021 Dec;177:31-47
Free radical biology & medicine 2021 Dec;177:31-47
Hsa_circ_0030586 promotes epithelial-mesenchymal transition in prostate cancer via PI3K-AKT signaling.
Luo GC, Chen L, Fang J, Yan ZJ
Bioengineered 2021 Dec;12(2):11089-11107
Bioengineered 2021 Dec;12(2):11089-11107
Circular RNA CNOT2 knockdown regulates twist family BHLH transcription factor via targeting microRNA 409-3p to prevent breast cancer invasion, migration and epithelial-mesenchymal transition.
Su Q, Shen H, Gu B, Zhu N
Bioengineered 2021 Dec;12(1):9058-9069
Bioengineered 2021 Dec;12(1):9058-9069
Long non-coding RNA VCAN-AS1 promotes the malignant behaviors of breast cancer by regulating the miR-106a-5p-mediated STAT3/HIF-1α pathway.
Du P, Luo K, Li G, Zhu J, Xiao Q, Li Y, Zhang X
Bioengineered 2021 Dec;12(1):5028-5044
Bioengineered 2021 Dec;12(1):5028-5044
Knockdown of carbohydrate sulfotransferase 12 decreases the proliferation and mobility of glioblastoma cells via the WNT/β-catenin pathway.
Wang J, Xia X, Tao X, Zhao P, Deng C
Bioengineered 2021 Dec;12(1):3934-3946
Bioengineered 2021 Dec;12(1):3934-3946
SETD8 induces stemness and epithelial-mesenchymal transition of pancreatic cancer cells by regulating ROR1 expression.
Liu M, Shi Y, Hu Q, Qin Y, Ji S, Liu W, Zhuo Q, Fan G, Ye Z, Song C, Yu X, Xu X, Xu W
Acta biochimica et biophysica Sinica 2021 Dec 8;53(12):1614-1624
Acta biochimica et biophysica Sinica 2021 Dec 8;53(12):1614-1624
Long non-coding RNA CRNDE exacerbates NPC advancement mediated by the miR-545-5p/CCND2 axis.
Ge S, Jiang C, Li M, Cheng Z, Feng X
Cancer cell international 2021 Dec 4;21(1):650
Cancer cell international 2021 Dec 4;21(1):650
USP3 promotes gastric cancer progression and metastasis by deubiquitination-dependent COL9A3/COL6A5 stabilisation.
Wu X, Wang H, Zhu D, Chai Y, Wang J, Dai W, Xiao Y, Tang W, Li J, Hong L, Pei M, Zhang J, Lin Z, Wang J, Li A, Liu S
Cell death & disease 2021 Dec 20;13(1):10
Cell death & disease 2021 Dec 20;13(1):10
Identification of key genes as predictive biomarkers for osteosarcoma metastasis using translational bioinformatics.
Ding FP, Tian JY, Wu J, Han DF, Zhao D
Cancer cell international 2021 Dec 2;21(1):640
Cancer cell international 2021 Dec 2;21(1):640
TMED3 exerts a protumor function in non-small cell lung cancer by enhancing the Wnt/β-catenin pathway via regulation of AKT.
Zhang D, Sun L, Zhang J
Toxicology and applied pharmacology 2021 Dec 15;433:115793
Toxicology and applied pharmacology 2021 Dec 15;433:115793
MiR-26b-5p inhibits cell proliferation and EMT by targeting MYCBP in triple-negative breast cancer.
Ma S, Wei H, Wang C, Han J, Chen X, Li Y
Cellular & molecular biology letters 2021 Dec 11;26(1):52
Cellular & molecular biology letters 2021 Dec 11;26(1):52
The miR-223-3p/MAP1B axis aggravates TGF-β-induced proliferation and migration of BPH-1 cells.
Wang Z, Zhang Y, Zhao C, Li Y, Hu X, Wu L, Chen M, Tong S
Cellular signalling 2021 Aug;84:110004
Cellular signalling 2021 Aug;84:110004
ATF3 inhibits arsenic-induced malignant transformation of human bronchial epithelial cells by attenuating inflammation.
Shi Q, Hu B, Yang C, Deng S, Cheng X, Wu J, Qi N
Toxicology 2021 Aug;460:152890
Toxicology 2021 Aug;460:152890
TMEM229A suppresses non‑small cell lung cancer progression via inactivating the ERK pathway.
Zhang X, He Y, Jiang Y, Bao Y, Chen Q, Xie D, Yu H, Wang X
Oncology reports 2021 Aug;46(2)
Oncology reports 2021 Aug;46(2)
Chromium (VI) promotes EMT by regulating FLNA in BLCA.
Sheng F, Chen KX, Liu J, Li JX, Liang GH, Xu Y, Du E, Zhang ZH
Environmental toxicology 2021 Aug;36(8):1694-1701
Environmental toxicology 2021 Aug;36(8):1694-1701
W436, a novel SMART derivative, exhibits anti-hepatocarcinoma activity by inducing apoptosis and G2/M cell cycle arrest in vitro and in vivo and induces protective autophagy.
Man S, Wu Z, Sun R, Guan Q, Li Z, Zuo D, Zhang W, Wu Y
Journal of biochemical and molecular toxicology 2021 Aug;35(8):e22831
Journal of biochemical and molecular toxicology 2021 Aug;35(8):e22831
miR‑200b upregulation promotes migration of BEAS‑2B cells following long‑term exposure to cigarette smoke by targeting ETS1.
Wang J, Yao R, Luo Q, Tan L, Jia B, Ouyang N, Li Y, Tong J, Li J
Molecular medicine reports 2021 Aug;24(2)
Molecular medicine reports 2021 Aug;24(2)
Tripterygium glycoside suppresses epithelial‑to‑mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway.
Tao M, Zheng D, Liang X, Wu D, Hu K, Jin J, He Q
Molecular medicine reports 2021 Aug;24(2)
Molecular medicine reports 2021 Aug;24(2)
Melatonin inhibits gallbladder cancer cell migration and invasion via ERK-mediated induction of epithelial-to-mesenchymal transition.
Tang H, Shi X, Zhu P, Guo W, Li J, Yan B, Zhang S
Oncology letters 2021 Aug;22(2):609
Oncology letters 2021 Aug;22(2):609
Depletion of CIP2A inhibits the proliferation, migration, invasion and epithelial-mesenchymal transition of glioma cells.
Xu Z, Chen X, Hegazy AM, Zhang S, Liu X, Tian J, Wu J, Shi F, Li L, Niu X, Pu J
Brain research bulletin 2021 Aug;173:14-21
Brain research bulletin 2021 Aug;173:14-21
Caveolin-1 facilitates cell migration by upregulating nuclear receptor 4A2/retinoid X receptor α-mediated β-galactoside α2,6-sialyltransferase I expression in human hepatocarcinoma cells.
Chen X, Wang L, Yu X, Wang S, Zhang J
The international journal of biochemistry & cell biology 2021 Aug;137:106027
The international journal of biochemistry & cell biology 2021 Aug;137:106027
MD2 blockage prevents the migration and invasion of hepatocellular carcinoma cells via inhibition of the EGFR signaling pathway.
Qi Y, Fang Q, Li Q, Ding H, Shu Q, Hu Y, Xin W, Fang L
Journal of gastrointestinal oncology 2021 Aug;12(4):1873-1883
Journal of gastrointestinal oncology 2021 Aug;12(4):1873-1883
Association of CASC18/miR-20a-3p/TGFB2 ceRNA axis with occult lymph node metastasis in tongue squamous cell carcinoma.
Zhou B, Zhou Y, Liu Y, Zhang H, Mao H, Peng M, Xu A, Li Z, Wang H, Tan H, Ren H, Zhou X, Long Y
Molecular medicine (Cambridge, Mass.) 2021 Aug 6;27(1):85
Molecular medicine (Cambridge, Mass.) 2021 Aug 6;27(1):85
Cyanidin-3-glucoside suppresses the progression of lung adenocarcinoma by downregulating TP53I3 and inhibiting PI3K/AKT/mTOR pathway.
Chen X, Zhang W, Xu X
World journal of surgical oncology 2021 Aug 6;19(1):232
World journal of surgical oncology 2021 Aug 6;19(1):232
IL-1β augments TGF-β inducing epithelial-mesenchymal transition of epithelial cells and associates with poor pulmonary function improvement in neutrophilic asthmatics.
Zhang S, Fan Y, Qin L, Fang X, Zhang C, Yue J, Bai W, Wang G, Chen Z, Renz H, Skevaki C, Liu X, Xie M
Respiratory research 2021 Aug 3;22(1):216
Respiratory research 2021 Aug 3;22(1):216
Low-Intensity Extracorporeal Shock Wave Therapy Promotes Bladder Regeneration and Improves Overactive Bladder Induced by Ovarian Hormone Deficiency from Rat Animal Model to Human Clinical Trial.
Lin KL, Lu JH, Chueh KS, Juan TJ, Wu BN, Chuang SM, Lee YC, Shen MC, Long CY, Juan YS
International journal of molecular sciences 2021 Aug 27;22(17)
International journal of molecular sciences 2021 Aug 27;22(17)
Apatinib triggers autophagic and apoptotic cell death via VEGFR2/STAT3/PD-L1 and ROS/Nrf2/p62 signaling in lung cancer.
Xie C, Zhou X, Liang C, Li X, Ge M, Chen Y, Yin J, Zhu J, Zhong C
Journal of experimental & clinical cancer research : CR 2021 Aug 24;40(1):266
Journal of experimental & clinical cancer research : CR 2021 Aug 24;40(1):266
2-Hydroxypropyl-β-cyclodextrin Regulates the Epithelial to Mesenchymal Transition in Breast Cancer Cells by Modulating Cholesterol Homeostasis and Endoplasmic Reticulum Stress.
Zhao Y, He L, Wang T, Zhu L, Yan N
Metabolites 2021 Aug 23;11(8)
Metabolites 2021 Aug 23;11(8)
Macrophage polarization-associated lnc-Ma301 interacts with caprin-1 to inhibit hepatocellular carcinoma metastasis through the Akt/Erk1 pathway.
Luo HL, Luo T, Liu JJ, Wu FX, Bai T, Ou C, Chen J, Li LQ, Zhong JH
Cancer cell international 2021 Aug 10;21(1):422
Cancer cell international 2021 Aug 10;21(1):422
Rab1A promotes cell proliferation and migration by upregulating Gli1 in colorectal cancer.
Peng C, Li X, Ye Z, Wu W
Scientific reports 2021 Aug 10;11(1):16243
Scientific reports 2021 Aug 10;11(1):16243
Colorectal Cancer Stem Cell States Uncovered by Simultaneous Single-Cell Analysis of Transcriptome and Telomeres.
Wang H, Gong P, Chen T, Gao S, Wu Z, Wang X, Li J, Marjani SL, Costa J, Weissman SM, Qi F, Pan X, Liu L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Apr;8(8):2004320
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 Apr;8(8):2004320
CRSP8 promotes thyroid cancer progression by antagonizing IKKα-induced cell differentiation.
Liao Y, Hua Y, Li Y, Zhang C, Yu W, Guo P, Zou K, Li W, Sun Y, Wang R, Zuo Y, Sui S, Tian C, Hao J, Chen M, Hu S, Chen M, Long Q, Wang X, Zou L, Xie F, Guo W, Deng W
Cell death and differentiation 2021 Apr;28(4):1347-1363
Cell death and differentiation 2021 Apr;28(4):1347-1363
Fusobacterium nucleatum Promotes Cisplatin-Resistance and Migration of Oral Squamous Carcinoma Cells by Up-Regulating Wnt5a-Mediated NFATc3 Expression.
Da J, Wang X, Li L, Xu Y
The Tohoku journal of experimental medicine 2021 Apr;253(4):249-259
The Tohoku journal of experimental medicine 2021 Apr;253(4):249-259
The miR-136-5p/ROCK1 axis suppresses invasion and migration, and enhances cisplatin sensitivity in head and neck cancer cells.
Yang B, Zang J, Yuan W, Jiang X, Zhang F
Experimental and therapeutic medicine 2021 Apr;21(4):317
Experimental and therapeutic medicine 2021 Apr;21(4):317
SPT6 recruits SND1 to co-activate human telomerase reverse transcriptase to promote colon cancer progression.
Diao C, Guo P, Yang W, Sun Y, Liao Y, Yan Y, Zhao A, Cai X, Hao J, Hu S, Yu W, Chen M, Wang R, Li W, Zuo Y, Pan J, Hua C, Lu X, Fan W, Zheng Z, Deng W, Luo G, Guo W
Molecular oncology 2021 Apr;15(4):1180-1202
Molecular oncology 2021 Apr;15(4):1180-1202
H. sinensis mycelium inhibits epithelial-mesenchymal transition by inactivating the midkine pathway in pulmonary fibrosis.
Lu L, Zhu H, Wang H, Liang H, Hou Y, Dou H
Frontiers of medicine 2021 Apr;15(2):313-329
Frontiers of medicine 2021 Apr;15(2):313-329
Abnormal spindle-like microcephaly-associated protein enhances cell invasion through Wnt/β-catenin-dependent regulation of epithelial-mesenchymal transition in non-small cell lung cancer cells.
Xia C, Xu X, Ding Y, Yu C, Qiao J, Liu P
Journal of thoracic disease 2021 Apr;13(4):2460-2474
Journal of thoracic disease 2021 Apr;13(4):2460-2474
Effects of miR-132-3p on progress and epithelial mesenchymal transition of non-small cell lung cancer via regulating KLF7.
Wang N, Xu Y, Guo Q, Zhu C, Zhao W, Qian W, Zheng M
Journal of thoracic disease 2021 Apr;13(4):2426-2436
Journal of thoracic disease 2021 Apr;13(4):2426-2436
FZD2 promotes TGF-β-induced epithelial-to-mesenchymal transition in breast cancer via activating notch signaling pathway.
Tuluhong D, Chen T, Wang J, Zeng H, Li H, Dunzhu W, Li Q, Wang S
Cancer cell international 2021 Apr 8;21(1):199
Cancer cell international 2021 Apr 8;21(1):199
Screening and identification of haptoglobin showing its important role in pathophysiological process of gallbladder carcinoma.
Guo L, Liu M, Dou Y, Duan R, Shen L, Jia L, Wang J, Li C, Li X, Liang T
Gene 2021 Apr 15;776:145429
Gene 2021 Apr 15;776:145429
Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer.
Gudi RR, Janakiraman H, Howe PH, Palanisamy V, Vasu C
Oncotarget 2021 Apr 13;12(8):807-822
Oncotarget 2021 Apr 13;12(8):807-822
ADAMTS19 Suppresses Cell Migration and Invasion by Targeting S100A16 via the NF-κB Pathway in Human Gastric Cancer.
Jiang Y, Yu X, Zhao Y, Huang J, Li T, Chen H, Zhou J, Huang Z, Yang Z
Biomolecules 2021 Apr 12;11(4)
Biomolecules 2021 Apr 12;11(4)
Inhibition of growth and metastasis of breast cancer by targeted delivery of 17-hydroxy-jolkinolide B via hyaluronic acid-coated liposomes.
Liu D, Zhang Q, Wang J, Guan S, Cai D, Liu J
Carbohydrate polymers 2021 Apr 1;257:117572
Carbohydrate polymers 2021 Apr 1;257:117572
TET1 may contribute to hypoxia-induced epithelial to mesenchymal transition of endometrial epithelial cells in endometriosis.
Wu J, Li X, Huang H, Xia X, Zhang M, Fang X
PeerJ 2020;8:e9950
PeerJ 2020;8:e9950
Histone Deacetylases Inhibit the Snail2-Mediated EMT During Metastasis of Hepatocellular Carcinoma Cells.
Hu Y, Nie Q, Dai M, Chen F, Wu H
Frontiers in cell and developmental biology 2020;8:752
Frontiers in cell and developmental biology 2020;8:752
Hypoxia-Inducible Ubiquitin Specific Peptidase 13 Contributes to Tumor Growth and Metastasis via Enhancing the Toll-Like Receptor 4/Myeloid Differentiation Primary Response Gene 88/Nuclear Factor-κB Pathway in Hepatocellular Carcinoma.
Gao S, Chen T, Li L, Liu X, Liu Y, Zhao J, Lu Q, Zeng Z, Xu Q, Huang D, Tu K
Frontiers in cell and developmental biology 2020;8:587389
Frontiers in cell and developmental biology 2020;8:587389
A Novel Van der Woude Syndrome-Causing IRF6 Variant Is Subject to Incomplete Non-sense-Mediated mRNA Decay Affecting the Phenotype of Keratinocytes.
Degen M, Girousi E, Feldmann J, Parisi L, La Scala GC, Schnyder I, Schaller A, Katsaros C
Frontiers in cell and developmental biology 2020;8:583115
Frontiers in cell and developmental biology 2020;8:583115
miR-193a-3p Mediates Placenta Accreta Spectrum Development by Targeting EFNB2 via Epithelial-Mesenchymal Transition Pathway Under Decidua Defect Conditions.
Li N, Hou R, Yang T, Liu C, Wei J
Frontiers in molecular biosciences 2020;7:613802
Frontiers in molecular biosciences 2020;7:613802
Keratin 17 Suppresses Cell Proliferation and Epithelial-Mesenchymal Transition in Pancreatic Cancer.
Zeng Y, Zou M, Liu Y, Que K, Wang Y, Liu C, Gong J, You Y
Frontiers in medicine 2020;7:572494
Frontiers in medicine 2020;7:572494
miR-124-3p Suppresses the Invasiveness and Metastasis of Hepatocarcinoma Cells via Targeting CRKL.
Majid A, Wang J, Nawaz M, Abdul S, Ayesha M, Guo C, Liu Q, Liu S, Sun MZ
Frontiers in molecular biosciences 2020;7:223
Frontiers in molecular biosciences 2020;7:223
PKM2 Promotes Breast Cancer Progression by Regulating Epithelial Mesenchymal Transition.
Xiao H, Zhang L, Chen Y, Zhou C, Wang X, Wang D, Liu Z
Analytical cellular pathology (Amsterdam) 2020;2020:8396023
Analytical cellular pathology (Amsterdam) 2020;2020:8396023
Anticancer Activity of Modified Tongyou Decoction on Eca109 Esophageal Cancer Cell Invasion and Metastasis through Regulation of the Epithelial-Mesenchymal Transition Mediated by the HIF-1α-Snail Axis.
Jia Y, Yan X, Cao Y, Song W, Zhang G, Hu X
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3053506
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3053506
GDF15 Repression Contributes to 5-Fluorouracil Resistance in Human Colon Cancer by Regulating Epithelial-Mesenchymal Transition and Apoptosis.
Wang B, Ma N, Zheng X, Li X, Ma X, Hu J, Cao B
BioMed research international 2020;2020:2826010
BioMed research international 2020;2020:2826010
miR-876 Inhibits EMT and Liver Fibrosis via POSTN to Suppress Metastasis in Hepatocellular Carcinoma.
Chen K, Li Z, Zhang M, Wang B, Peng T, Shen Y, Zhang J, Ye J, Liu Y, Tang D, Peng M, Ma D, Xiao Z, Zhang Y, Jin W, Li X
BioMed research international 2020;2020:1964219
BioMed research international 2020;2020:1964219
The Significance of Circular RNA DDX17 in Prostate Cancer.
Lin Q, Cai J, Wang QQ
BioMed research international 2020;2020:1878431
BioMed research international 2020;2020:1878431
BTG1 inhibits malignancy as a novel prognosis signature in endometrial carcinoma.
Li Y, Huo J, He J, Zhang Y, Ma X
Cancer cell international 2020;20:490
Cancer cell international 2020;20:490
Down-regulation of TRIB3 inhibits the progression of ovarian cancer via MEK/ERK signaling pathway.
Wang S, Wang C, Li X, Hu Y, Gou R, Guo Q, Nie X, Liu J, Zhu L, Lin B
Cancer cell international 2020;20:418
Cancer cell international 2020;20:418
miR-454 suppresses the proliferation and invasion of ovarian cancer by targeting E2F6.
An Y, Zhang J, Cheng X, Li B, Tian Y, Zhang X, Zhao F
Cancer cell international 2020;20:237
Cancer cell international 2020;20:237
HBx mediated Increase of SIRT1 Contributes to HBV-related Hepatocellular Carcinoma Tumorigenesis.
Wang Q, Cheng ST, Chen J
International journal of medical sciences 2020;17(12):1783-1794
International journal of medical sciences 2020;17(12):1783-1794
Cdh1 functions as an oncogene by inducing self-renewal of lung cancer stem-like cells via oncogenic pathways.
Ye T, Li J, Sun Z, Liu D, Zeng B, Zhao Q, Wang J, Xing HR
International journal of biological sciences 2020;16(3):447-459
International journal of biological sciences 2020;16(3):447-459
Lin28A Regulates Stem-like Properties of Ovarian Cancer Cells by Enriching RAN and HSBP1 mRNA and Up-regulating its Protein Expression.
Zhong Y, Cao L, Ma H, Wang Q, Wei P, Yang J, Mo Y, Cao L, Shuai C, Peng S
International journal of biological sciences 2020;16(11):1941-1953
International journal of biological sciences 2020;16(11):1941-1953
S100A6 promotes proliferation and migration of HepG2 cells via increased ubiquitin-dependent degradation of p53.
Song D, Xu B, Shi D, Li S, Cai Y
Open medicine (Warsaw, Poland) 2020;15(1):317-326
Open medicine (Warsaw, Poland) 2020;15(1):317-326
Paeoniflorin Alleviates Abnormalities in Rats with Functional Dyspepsia by Stimulating the Release of Acetylcholine.
Zou X, Wang Y, Wang Y, Yang J, Guo H, Cai Z
Drug design, development and therapy 2020;14:5623-5632
Drug design, development and therapy 2020;14:5623-5632
Treatment with a PPAR-γ Agonist Protects Against Hyperuricemic Nephropathy in a Rat Model.
Wang X, Deng J, Xiong C, Chen H, Zhou Q, Xia Y, Shao X, Zou H
Drug design, development and therapy 2020;14:2221-2233
Drug design, development and therapy 2020;14:2221-2233
miR-370-3p Alleviates Ulcerative Colitis-Related Colorectal Cancer in Mice Through Inhibiting the Inflammatory Response and Epithelial-Mesenchymal Transition.
Lin L, Wang D, Qu S, Zhao H, Lin Y
Drug design, development and therapy 2020;14:1127-1141
Drug design, development and therapy 2020;14:1127-1141
Cigarette smoke supports stemness and epithelial-mesenchymal transition in bladder cancer stem cells through SHH signaling.
Sun X, Song J, Li E, Geng H, Li Y, Yu D, Zhong C
International journal of clinical and experimental pathology 2020;13(6):1333-1348
International journal of clinical and experimental pathology 2020;13(6):1333-1348
The role of Stim1 in the progression of lupus nephritis in mice.
Zhang F, Zhou X, Cui D, Zhang W, Lai J, Li X, Ruan Y, Xie Y, Shi M, Xiao Y, Wang Y, Zhou Y, Guo B
International journal of clinical and experimental pathology 2020;13(12):3021-3032
International journal of clinical and experimental pathology 2020;13(12):3021-3032
MicroRNA 885-5p Inhibits Hepatocellular Carcinoma Metastasis by Repressing AEG1.
Li C, Wang X, Song Q
OncoTargets and therapy 2020;13:981-988
OncoTargets and therapy 2020;13:981-988
MicroRNA-623 Inhibits Epithelial-Mesenchymal Transition to Attenuate Glioma Proliferation by Targeting TRIM44.
Cui D, Wang K, Liu Y, Gao J, Cui J
OncoTargets and therapy 2020;13:9291-9303
OncoTargets and therapy 2020;13:9291-9303
Characterization of Triple-Negative Breast Cancer MDA-MB-231 Cell Spheroid Model.
Huang Z, Yu P, Tang J
OncoTargets and therapy 2020;13:5395-5405
OncoTargets and therapy 2020;13:5395-5405
Low-Dose Radiation Promotes Invasion and Migration of A549 Cells by Activating the CXCL1/NF-κB Signaling Pathway.
Li J, Wu DM, Han R, Yu Y, Deng SH, Liu T, Zhang T, Xu Y
OncoTargets and therapy 2020;13:3619-3629
OncoTargets and therapy 2020;13:3619-3629
Dihydroartemisinin Prevents Progression and Metastasis of Head and Neck Squamous Cell Carcinoma by Inhibiting Polarization of Macrophages in Tumor Microenvironment.
Chen R, Lu X, Li Z, Sun Y, He Z, Li X
OncoTargets and therapy 2020;13:3375-3387
OncoTargets and therapy 2020;13:3375-3387
Rap2c as a Novel Biomarker for Predicting Poor Prognosis in Glioma.
Wang X, Wang C, Xi L, Yu Z
OncoTargets and therapy 2020;13:3073-3083
OncoTargets and therapy 2020;13:3073-3083
Long Non-Coding RNA SPRY4-IT1 Reverses Cisplatin Resistance by Downregulating MPZL-1 via Suppressing EMT in NSCLC.
Ye Y, Gu J, Liu P, Wang H, Jiang L, Lei T, Yu S, Han G, Wang Z
OncoTargets and therapy 2020;13:2783-2793
OncoTargets and therapy 2020;13:2783-2793
Fibroblast Activation Protein (FAP) Overexpression Induces Epithelial-Mesenchymal Transition (EMT) in Oral Squamous Cell Carcinoma by Down-Regulating Dipeptidyl Peptidase 9 (DPP9).
Wu QQ, Zhao M, Huang GZ, Zheng ZN, Chen Y, Zeng WS, Lv XZ
OncoTargets and therapy 2020;13:2599-2611
OncoTargets and therapy 2020;13:2599-2611
Tumor Suppressor microRNA-138 Suppresses Low-Grade Glioma Development and Metastasis via Regulating IGF2BP2.
Yang Y, Liu X, Cheng L, Li L, Wei Z, Wang Z, Han G, Wan X, Wang Z, Zhang J, Chen C
OncoTargets and therapy 2020;13:2247-2260
OncoTargets and therapy 2020;13:2247-2260
TIM-3 Participates in the Invasion and Metastasis of Nasopharyngeal Carcinoma via SMAD7/SMAD2/SNAIL1 Axis-Mediated Epithelial-Mesenchymal Transition.
Xiao Y, Qing J, Li B, Chen L, Nong S, Yang W, Tang X, Chen Z
OncoTargets and therapy 2020;13:1993-2006
OncoTargets and therapy 2020;13:1993-2006
Empagliflozin Protects Against Proximal Renal Tubular Cell Injury Induced by High Glucose via Regulation of Hypoxia-Inducible Factor 1-Alpha.
Ndibalema AR, Kabuye D, Wen S, Li L, Li X, Fan Q
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:1953-1967
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:1953-1967
Profiling and Integrated Analysis of Differentially Expressed Circular RNAs in Plasma Exosomes as Novel Biomarkers for Advanced-Stage Lung Adenocarcinoma.
Lin S, Xiong W, Liu H, Pei L, Yi H, Guan Y
OncoTargets and therapy 2020;13:12965-12977
OncoTargets and therapy 2020;13:12965-12977
MST4 Regulates Epithelial-Mesenchymal Transition of Choriocarcinoma by Mediating TGF-β1 Expression.
Yu H, Zhang W, Han P, Yang B, Feng X, Zhou P, Zhu X, Zhou B, Chen W, Qian J, Yu J
OncoTargets and therapy 2020;13:11935-11946
OncoTargets and therapy 2020;13:11935-11946
Simultaneous Inhibition of Ornithine Decarboxylase 1 and Pyruvate Kinase M2 Exerts Synergistic Effects Against Hepatocellular Carcinoma Cells.
Zeng Z, Lan J, Lei S, Yang Y, He Z, Xue Y, Chen T
OncoTargets and therapy 2020;13:11697-11709
OncoTargets and therapy 2020;13:11697-11709
Prognostic Significance and Related Mechanisms of Hexokinase 1 in Ovarian Cancer.
Li Y, Tian H, Luo H, Fu J, Jiao Y, Li Y
OncoTargets and therapy 2020;13:11583-11594
OncoTargets and therapy 2020;13:11583-11594
CircHIPK3 Promotes Gemcitabine (GEM) Resistance in Pancreatic Cancer Cells by Sponging miR-330-5p and Targets RASSF1.
Liu Y, Xia L, Dong L, Wang J, Xiao Q, Yu X, Zhu H
Cancer management and research 2020;12:921-929
Cancer management and research 2020;12:921-929
Downregulation of Immortalization-Upregulated Protein Suppresses the Progression of Breast Cancer Cell Lines by Regulating Epithelial-Mesenchymal Transition.
Wen J, Lin L, Lin B, Xia E, Qu J, Wang O
Cancer management and research 2020;12:8631-8642
Cancer management and research 2020;12:8631-8642
Blocking circ_0000520 Suppressed Breast Cancer Cell Growth, Migration and Invasion Partially via miR-1296/SP1 Axis Both in vitro and in vivo.
Zang H, Li Y, Zhang X, Huang G
Cancer management and research 2020;12:7783-7795
Cancer management and research 2020;12:7783-7795
Blocking circ_0013912 Suppressed Cell Growth, Migration and Invasion of Pancreatic Ductal Adenocarcinoma Cells in vitro and in vivo Partially Through Sponging miR-7-5p.
Guo W, Zhao L, Wei G, Liu P, Zhang Y, Fu L
Cancer management and research 2020;12:7291-7303
Cancer management and research 2020;12:7291-7303
LINC00963 Promotes Ovarian Cancer Proliferation, Migration and EMT via the miR-378g /CHI3L1 Axis.
Liu W, Yang YJ, An Q
Cancer management and research 2020;12:463-473
Cancer management and research 2020;12:463-473
KLHL22 Regulates the EMT and Proliferation in Colorectal Cancer Cells in Part via the Wnt/β-Catenin Signaling Pathway.
Song Y, Yuan H, Wang J, Wu Y, Xiao Y, Mao S
Cancer management and research 2020;12:3981-3993
Cancer management and research 2020;12:3981-3993
CUB Domain-Containing Protein-1 Promotes Proliferation, Migration and Invasion in Cervical Cancer Cells.
Huang L, Chen Y, Lai S, Guan H, Hu X, Liu J, Zhang H, Zhang Z, Zhou J
Cancer management and research 2020;12:3759-3769
Cancer management and research 2020;12:3759-3769
NUDT21 Suppresses Breast Cancer Tumorigenesis Through Regulating CPSF6 Expression.
Wang BJ, Liu DC, Guo QY, Han XW, Bi XM, Wang H, Wu ZS, Wu WY
Cancer management and research 2020;12:3069-3078
Cancer management and research 2020;12:3069-3078
METTL14 Inhibits Hepatocellular Carcinoma Metastasis Through Regulating EGFR/PI3K/AKT Signaling Pathway in an m6A-Dependent Manner.
Shi Y, Zhuang Y, Zhang J, Chen M, Wu S
Cancer management and research 2020;12:13173-13184
Cancer management and research 2020;12:13173-13184
Circadian Clock Protein PERIOD2 Suppresses the PI3K/Akt Pathway and Promotes Cisplatin Sensitivity in Ovarian Cancer.
Wang Z, Li F, Wei M, Zhang S, Wang T
Cancer management and research 2020;12:11897-11908
Cancer management and research 2020;12:11897-11908
Cytokine TNF-α promotes invasion and metastasis of gastric cancer by down-regulating Pentraxin3.
Cui X, Zhang H, Cao A, Cao L, Hu X
Journal of Cancer 2020;11(7):1800-1807
Journal of Cancer 2020;11(7):1800-1807
TRIM67 Promotes the Proliferation, Migration, and Invasion of Non-Small-Cell Lung Cancer by Positively Regulating the Notch Pathway.
Jiang J, Ren H, Xu Y, Wudu M, Wang Q, Liu Z, Su H, Jiang X, Zhang Y, Zhang B, Qiu X
Journal of Cancer 2020;11(5):1240-1249
Journal of Cancer 2020;11(5):1240-1249
Biological implications of PTEN upregulation and altered sodium/iodide symporter intracellular distribution in resveratrol-suppressed anaplastic thyroid cancer cells.
Xiong L, Nie JH, Lin XM, Wu JB, Chen Z, Xu B, Liu J
Journal of Cancer 2020;11(23):6883-6891
Journal of Cancer 2020;11(23):6883-6891
Total saponins from Lilium lancifolium: a promising alternative to inhibit the growth of gastric carcinoma cells.
Zhang YY, Luo LM, Wang YX, Zhu N, Zhao TJ, Qin L
Journal of Cancer 2020;11(14):4261-4273
Journal of Cancer 2020;11(14):4261-4273
TNFAIP8 promotes the migration of clear cell renal cell carcinoma by regulating the EMT.
Zhong M, Zhu M, Liu Y, Lin Y, Wang L, Ye Y, Chen H, Yang Y, Zhuang G, Huang J
Journal of Cancer 2020;11(10):3061-3071
Journal of Cancer 2020;11(10):3061-3071
P4HA2 contributes to cervical cancer progression via inducing epithelial-mesenchymal transition.
Cao Y, Han Q, Li J, Jia Y, Zhang R, Shi H
Journal of Cancer 2020;11(10):2788-2799
Journal of Cancer 2020;11(10):2788-2799
Vitamin C Inhibits Metastasis of Peritoneal Tumors By Preventing Spheroid Formation in ID8 Murine Epithelial Peritoneal Cancer Model.
Xu Y, Guo X, Wang G, Zhou C
Frontiers in pharmacology 2020;11:645
Frontiers in pharmacology 2020;11:645
Sanguisorba officinalis L. Suppresses Triple-Negative Breast Cancer Metastasis by Inhibiting Late-Phase Autophagy via Hif-1α/Caveolin-1 Signaling.
Wang N, Muhetaer G, Zhang X, Yang B, Wang C, Zhang Y, Wang X, Zhang J, Wang S, Zheng Y, Zhang F, Wang Z
Frontiers in pharmacology 2020;11:591400
Frontiers in pharmacology 2020;11:591400
Hyperoside Attenuates Bleomycin-Induced Pulmonary Fibrosis Development in Mice.
Huang J, Tong X, Zhang L, Zhang Y, Wang L, Wang D, Zhang S, Fan H
Frontiers in pharmacology 2020;11:550955
Frontiers in pharmacology 2020;11:550955
Trimetazidine Inhibits Renal Tubular Epithelial Cells to Mesenchymal Transition in Diabetic Rats via Upregulation of Sirt1.
Yang Y, Wang Y, He Z, Liu Y, Chen C, Wang Y, Wang DW, Wang H
Frontiers in pharmacology 2020;11:1136
Frontiers in pharmacology 2020;11:1136
GADD45B Promotes Glucose-Induced Renal Tubular Epithelial-Mesenchymal Transition and Apoptosis via the p38 MAPK and JNK Signaling Pathways.
Xue M, Sun H, Xu R, Wang Y, Guo J, Li X, Cheng Y, Xu C, Tang C, Sun B, Chen L
Frontiers in physiology 2020;11:1074
Frontiers in physiology 2020;11:1074
SMYD2 suppresses APC2 expression to activate the Wnt/β-catenin pathway and promotes epithelial-mesenchymal transition in colorectal cancer.
Meng F, Liu X, Lin C, Xu L, Liu J, Zhang P, Zhang X, Song J, Yan Y, Ren Z, Zhang Y
American journal of cancer research 2020;10(3):997-1011
American journal of cancer research 2020;10(3):997-1011
Non-canonical signaling pathway of SNAI2 induces EMT in ovarian cancer cells by suppressing miR-222-3p transcription and upregulating PDCD10.
Fan L, Lei H, Zhang S, Peng Y, Fu C, Shu G, Yin G
Theranostics 2020;10(13):5895-5913
Theranostics 2020;10(13):5895-5913
BYSL Promotes Glioblastoma Cell Migration, Invasion, and Mesenchymal Transition Through the GSK-3β/β-Catenin Signaling Pathway.
Sha Z, Zhou J, Wu Y, Zhang T, Li C, Meng Q, Musunuru PP, You F, Wu Y, Yu R, Gao S
Frontiers in oncology 2020;10:565225
Frontiers in oncology 2020;10:565225
Folliculin Controls the Intracellular Survival and Trans-Epithelial Passage of Neisseria gonorrhoeae.
Yang T, Heydarian M, Kozjak-Pavlovic V, Urban M, Harbottle RP, Rudel T
Frontiers in cellular and infection microbiology 2020;10:422
Frontiers in cellular and infection microbiology 2020;10:422
Regulation of Integrin Subunit Alpha 2 by miR-135b-5p Modulates Chemoresistance in Gastric Cancer.
Wang Q, Cao T, Guo K, Zhou Y, Liu H, Pan Y, Hou Q, Nie Y, Fan D, Lu Y, Zhao X
Frontiers in oncology 2020;10:308
Frontiers in oncology 2020;10:308
Tumor mutation burden and JARID2 gene alteration are associated with short disease-free survival in locally advanced triple-negative breast cancer.
Zhang X, Li J, Yang Q, Wang Y, Li X, Liu Y, Shan B
Annals of translational medicine 2020 Sep;8(17):1052
Annals of translational medicine 2020 Sep;8(17):1052
Xanthan gum and locust bean gum substrate improves bovine embryo development.
Hara S, Aoki S, Nagata M, Shirasuna K, Noguchi T, Iwata H
Reproduction in domestic animals = Zuchthygiene 2020 Sep;55(9):1124-1131
Reproduction in domestic animals = Zuchthygiene 2020 Sep;55(9):1124-1131
Shikonin blocks human lung adenocarcinoma cell migration and invasion in the inflammatory microenvironment via the IL‑6/STAT3 signaling pathway.
Pan T, Zhang F, Li F, Gao X, Li Z, Li X, Ren X
Oncology reports 2020 Sep;44(3):1049-1063
Oncology reports 2020 Sep;44(3):1049-1063
RUNX3-dependent oxidative epithelial-to-mesenchymal transition in methamphetamine-induced chronic lung injury.
Shi L, Liu BY, Wang X, Zhu MJ, Chen L, Zhou MY, Gu YJ, Cheng L, Wang Y
Cell stress & chaperones 2020 Sep;25(5):793-802
Cell stress & chaperones 2020 Sep;25(5):793-802
Long non-coding RNA MALAT1 targeting STING transcription promotes bronchopulmonary dysplasia through regulation of CREB.
Chen JH, Feng DD, Chen YF, Yang CX, Juan CX, Cao Q, Chen X, Liu S, Zhou GP
Journal of cellular and molecular medicine 2020 Sep;24(18):10478-10492
Journal of cellular and molecular medicine 2020 Sep;24(18):10478-10492
AKR1C2 acts as a targetable oncogene in esophageal squamous cell carcinoma via activating PI3K/AKT signaling pathway.
Zhang ZF, Huang TJ, Zhang XK, Xie YJ, Lin ST, Luo FF, Meng DF, Hu H, Wang J, Peng LX, Qian CN, Cheng C, Huang BJ
Journal of cellular and molecular medicine 2020 Sep;24(17):9999-10012
Journal of cellular and molecular medicine 2020 Sep;24(17):9999-10012
Circular RNA hsa_circ_0005556 Accelerates Gastric Cancer Progression by Sponging miR-4270 to Increase MMP19 Expression.
Shen D, Zhao H, Zeng P, Song J, Yang Y, Gu X, Ji Q, Zhao W
Journal of gastric cancer 2020 Sep;20(3):300-312
Journal of gastric cancer 2020 Sep;20(3):300-312
Polyphyllin II inhibits human bladder cancer migration and invasion by regulating EMT-associated factors and MMPs.
Niu W, Xu L, Li J, Zhai Y, Sun Z, Shi W, Jiang Y, Ma C, Lin H, Guo Y, Liu Z
Oncology letters 2020 Sep;20(3):2928-2936
Oncology letters 2020 Sep;20(3):2928-2936
PAK6 promotes cervical cancer progression through activation of the Wnt/β-catenin signaling pathway.
Yang Q, Zhao Y, Chen Y, Chang Y, Huang A, Xu T, Li G, Wu G
Oncology letters 2020 Sep;20(3):2387-2395
Oncology letters 2020 Sep;20(3):2387-2395
BAIAP2L2 promotes the progression of gastric cancer via AKT/mTOR and Wnt3a/β-catenin signaling pathways.
Liu J, Shangguan Y, Sun J, Cong W, Xie Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110414
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110414
Novel long non-coding RNA LINC02323 promotes epithelial-mesenchymal transition and metastasis via sponging miR-1343-3p in lung adenocarcinoma.
Zhang X, Du L, Han J, Li X, Wang H, Zheng G, Wang Y, Yang Y, Hu Y, Wang C
Thoracic cancer 2020 Sep;11(9):2506-2516
Thoracic cancer 2020 Sep;11(9):2506-2516
The F-box protein FBXO11 restrains hepatocellular carcinoma stemness via promotion of ubiquitin-mediated degradation of Snail.
Shao L, Zhang X, Yao Q
FEBS open bio 2020 Sep;10(9):1810-1820
FEBS open bio 2020 Sep;10(9):1810-1820
Circular RNA circREPS2 Acts as a Sponge of miR-558 to Suppress Gastric Cancer Progression by Regulating RUNX3/β-catenin Signaling.
Guo X, Dai X, Liu J, Cheng A, Qin C, Wang Z
Molecular therapy. Nucleic acids 2020 Sep 4;21:577-591
Molecular therapy. Nucleic acids 2020 Sep 4;21:577-591
Porphyromonas gingivalis disrupts vascular endothelial homeostasis in a TLR-NF-κB axis dependent manner.
Xie M, Tang Q, Yu S, Sun J, Mei F, Zhao J, Chen L
International journal of oral science 2020 Sep 30;12(1):28
International journal of oral science 2020 Sep 30;12(1):28
2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol (SQ) inhibits cancer cell metastasis behavior of TNBC via suppressing EMT and VEGF.
Zheng D, Wu Z, Han J, Guan Q, Li Z, Zuo D, Zhang W, Wu Y
Chemico-biological interactions 2020 Sep 25;329:109202
Chemico-biological interactions 2020 Sep 25;329:109202
miR-7 Reduces Breast Cancer Stem Cell Metastasis via Inhibiting RELA to Decrease ESAM Expression.
Li M, Pan M, Wang J, You C, Zhao F, Zheng D, Guo M, Xu H, Wu D, Wang L, Dou J
Molecular therapy oncolytics 2020 Sep 25;18:70-82
Molecular therapy oncolytics 2020 Sep 25;18:70-82
LncRNA Mical2/miR-203a-3p sponge participates in epithelial-mesenchymal transition by targeting p66Shc in liver fibrosis.
Zhao Y, Wang Z, Zhou J, Feng D, Li Y, Hu Y, Zhang F, Chen Z, Wang G, Ma X, Tian X, Yao J
Toxicology and applied pharmacology 2020 Sep 15;403:115125
Toxicology and applied pharmacology 2020 Sep 15;403:115125
Chronic stress promotes EMT-mediated metastasis through activation of STAT3 signaling pathway by miR-337-3p in breast cancer.
Du P, Zeng H, Xiao Y, Zhao Y, Zheng B, Deng Y, Liu J, Huang B, Zhang X, Yang K, Jiang Y, Ma X
Cell death & disease 2020 Sep 15;11(9):761
Cell death & disease 2020 Sep 15;11(9):761
MEST promotes bladder cancer cell proliferation, migration and invasion via STAT3/Twist-1-mediated EMT.
Zhao C, Hu X, Tong S, Mo M, He W, Wang L, Li Y
Translational cancer research 2020 Oct;9(10):6178-6188
Translational cancer research 2020 Oct;9(10):6178-6188
Paris polyphylla ethanol extract induces G2/M arrest and suppresses migration and invasion in bladder cancer.
Liu Z, Sun Z, Zhang D, Ma C, Jiang Y, Cao G, Sun C, Li K, Xu D, Liu J, Zhao S
Translational cancer research 2020 Oct;9(10):5994-6004
Translational cancer research 2020 Oct;9(10):5994-6004
MYCT1 inhibits the EMT and migration of laryngeal cancer cells via the SP1/miR-629-3p/ESRP2 pathway.
Yue PJ, Sun YY, Li YH, Xu ZM, Fu WN
Cellular signalling 2020 Oct;74:109709
Cellular signalling 2020 Oct;74:109709
Blocking NFATc3 ameliorates azoxymethane/dextran sulfate sodium induced colitis-associated colorectal cancer in mice via the inhibition of inflammatory responses and epithelial-mesenchymal transition.
Lin Y, Koumba MH, Qu S, Wang D, Lin L
Cellular signalling 2020 Oct;74:109707
Cellular signalling 2020 Oct;74:109707
Elevated Expression of RIOK1 Is Correlated with Breast Cancer Hormone Receptor Status and Promotes Cancer Progression.
Huang Z, Li X, Xie T, Gu C, Ni K, Yin Q, Cao X, Zhang C
Cancer research and treatment 2020 Oct;52(4):1067-1083
Cancer research and treatment 2020 Oct;52(4):1067-1083
IL-6 induces tumor suppressor protein tyrosine phosphatase receptor type D by inhibiting miR-34a to prevent IL-6 signaling overactivation.
Zhang F, Wang B, Qin T, Wang L, Zhang Q, Lu Y, Song B, Yu X, Li L
Molecular and cellular biochemistry 2020 Oct;473(1-2):1-13
Molecular and cellular biochemistry 2020 Oct;473(1-2):1-13
SUMOylation of HSP27 regulates PKM2 to promote esophageal squamous cell carcinoma progression.
Zhang X, Liu T, Zheng S, Liu Q, Shen T, Han X, Zhang Q, Yang L, Lu X
Oncology reports 2020 Oct;44(4):1355-1364
Oncology reports 2020 Oct;44(4):1355-1364
Deubiquitinase USP29 promotes gastric cancer cell migration by cooperating with phosphatase SCP1 to stabilize Snail protein.
Qian W, Li Q, Wu X, Li W, Li Q, Zhang J, Li M, Zhang D, Zhao H, Zou X, Jia H, Zhang L, Yang XD, Hou Z
Oncogene 2020 Oct;39(44):6802-6815
Oncogene 2020 Oct;39(44):6802-6815
Melatonin synergizes BRAF-targeting agent dabrafenib for the treatment of anaplastic thyroid cancer by inhibiting AKT/hTERT signalling.
Liao Y, Gao Y, Chang A, Li Z, Wang H, Cao J, Gu W, Tang R
Journal of cellular and molecular medicine 2020 Oct;24(20):12119-12130
Journal of cellular and molecular medicine 2020 Oct;24(20):12119-12130
Emodin inhibiting neutrophil elastase-induced epithelial-mesenchymal transition through Notch1 signalling in alveolar epithelial cells.
Zhou L, Gao R, Hong H, Li X, Yang J, Shen W, Wang Z, Yang J
Journal of cellular and molecular medicine 2020 Oct;24(20):11998-12007
Journal of cellular and molecular medicine 2020 Oct;24(20):11998-12007
The PI3Kα inhibitor DFX24 suppresses tumor growth and metastasis in non-small cell lung cancer via ERK inhibition and EPHB6 reactivation.
Fan YH, Ding HW, Kim D, Liu JY, Hong JY, Xu YN, Wang D, Yang XS, Lee SK
Pharmacological research 2020 Oct;160:105147
Pharmacological research 2020 Oct;160:105147
APE1 promotes proliferation and migration of cutaneous squamous cell carcinoma.
Deng X, Zhen P, Niu X, Dai Y, Wang Y, Zhou M
Journal of dermatological science 2020 Oct;100(1):67-74
Journal of dermatological science 2020 Oct;100(1):67-74
Calreticulin promotes EMT in pancreatic cancer via mediating Ca(2+) dependent acute and chronic endoplasmic reticulum stress.
Sheng W, Wang G, Tang J, Shi X, Cao R, Sun J, Lin YH, Jia C, Chen C, Zhou J, Dong M
Journal of experimental & clinical cancer research : CR 2020 Oct 7;39(1):209
Journal of experimental & clinical cancer research : CR 2020 Oct 7;39(1):209
YTHDF2 mediates the mRNA degradation of the tumor suppressors to induce AKT phosphorylation in N6-methyladenosine-dependent way in prostate cancer.
Li J, Xie H, Ying Y, Chen H, Yan H, He L, Xu M, Xu X, Liang Z, Liu B, Wang X, Zheng X, Xie L
Molecular cancer 2020 Oct 29;19(1):152
Molecular cancer 2020 Oct 29;19(1):152
MicroRNA-200b/c-3p regulate epithelial plasticity and inhibit cutaneous wound healing by modulating TGF-β-mediated RAC1 signaling.
Tang H, Wang X, Zhang M, Yan Y, Huang S, Ji J, Xu J, Zhang Y, Cai Y, Yang B, Lan W, Huang M, Zhang L
Cell death & disease 2020 Oct 29;11(10):931
Cell death & disease 2020 Oct 29;11(10):931
Circular RNA circ_PVT1 induces epithelial-mesenchymal transition to promote metastasis of cervical cancer.
Wang H, Wei M, Kang Y, Xing J, Zhao Y
Aging 2020 Oct 27;12(20):20139-20151
Aging 2020 Oct 27;12(20):20139-20151
CUEDC1 inhibits epithelial-mesenchymal transition via the TβRI/Smad signaling pathway and suppresses tumor progression in non-small cell lung cancer.
Cui Y, Song Y, Yan S, Cao M, Huang J, Jia D, Liu Y, Zhang S, Fan W, Cai L, Li C, Xing Y
Aging 2020 Oct 25;12(20):20047-20068
Aging 2020 Oct 25;12(20):20047-20068
GATA6 promotes epithelial-mesenchymal transition and metastasis through MUC1/β-catenin pathway in cholangiocarcinoma.
Deng X, Jiang P, Chen J, Li J, Li D, He Y, Jiang Y, Zhang Y, Xu S, Li X, Wang S, Tian F
Cell death & disease 2020 Oct 15;11(10):860
Cell death & disease 2020 Oct 15;11(10):860
miR-15a-5p suppresses peritoneal fibrosis induced by peritoneal dialysis via targeting VEGF in rats.
He Q, Wen L, Wang L, Zhang Y, Yu W, Zhang F, Zhang W, Xiao J, Wen X, Zhao Z
Renal failure 2020 Nov;42(1):932-943
Renal failure 2020 Nov;42(1):932-943
Polydatin inhibits ZEB1-invoked epithelial-mesenchymal transition in fructose-induced liver fibrosis.
Zhao X, Yang Y, Yu H, Wu W, Sun Y, Pan Y, Kong L
Journal of cellular and molecular medicine 2020 Nov;24(22):13208-13222
Journal of cellular and molecular medicine 2020 Nov;24(22):13208-13222
MSCs reduce airway remodeling in the lungs of asthmatic rats through the Wnt/β-catenin signaling pathway.
Song J, Zhu XM, Wei QY
European review for medical and pharmacological sciences 2020 Nov;24(21):11199-11211
European review for medical and pharmacological sciences 2020 Nov;24(21):11199-11211
Long noncoding RNA SNHG12 modulated by human papillomavirus 16 E6/E7 promotes cervical cancer progression via ERK/Slug pathway.
Lai SY, Guan HM, Liu J, Huang LJ, Hu XL, Chen YH, Wu YH, Wang Y, Yang Q, Zhou JY
Journal of cellular physiology 2020 Nov;235(11):7911-7922
Journal of cellular physiology 2020 Nov;235(11):7911-7922
SUMO4 small interfering RNA attenuates invasion and migration via the JAK2/STAT3 pathway in non-small cell lung cancer cells.
Liang JX, Gao W, Zeng XW, Cheng GP, Cai L, Tao KY, Yang X
Oncology letters 2020 Nov;20(5):225
Oncology letters 2020 Nov;20(5):225
DEPDC1B promotes migration and invasion in pancreatic ductal adenocarcinoma by activating the Akt/GSK3β/Snail pathway.
Liu X, Li T, Huang X, Wu W, Li J, Wei L, Qian Y, Xu H, Wang Q, Wang L
Oncology letters 2020 Nov;20(5):146
Oncology letters 2020 Nov;20(5):146
SNHG1 promotes proliferation, migration and invasion of bladder cancer cells via the PI3K/AKT signaling pathway.
Du Q, Chen J
Experimental and therapeutic medicine 2020 Nov;20(5):110
Experimental and therapeutic medicine 2020 Nov;20(5):110
Wnt/β-Catenin Signaling Axis Is Required for TFEB-Mediated Gastric Cancer Metastasis and Epithelial-Mesenchymal Transition.
Li S, Liu F, Xu L, Li C, Yang X, Guo B, Gu J, Wang L
Molecular cancer research : MCR 2020 Nov;18(11):1650-1659
Molecular cancer research : MCR 2020 Nov;18(11):1650-1659
Anthocyanins from Aronia melanocarpa Induce Apoptosis in Caco-2 Cells through Wnt/β-Catenin Signaling Pathway.
Wei J, Yu W, Hao R, Fan J, Gao J
Chemistry & biodiversity 2020 Nov;17(11):e2000654
Chemistry & biodiversity 2020 Nov;17(11):e2000654
AGEs-RAGE axis causes endothelial-to-mesenchymal transition in early calcific aortic valve disease via TGF-β1 and BMPR2 signaling.
Deng G, Zhang L, Wang C, Wang S, Xu J, Dong J, Kang Q, Zhai X, Zhao Y, Shan Z
Experimental gerontology 2020 Nov;141:111088
Experimental gerontology 2020 Nov;141:111088
OXPHOS-dependent metabolic reprogramming prompts metastatic potential of breast cancer cells under osteogenic differentiation.
Hu Y, Xu W, Zeng H, He Z, Lu X, Zuo D, Qin G, Chen W
British journal of cancer 2020 Nov;123(11):1644-1655
British journal of cancer 2020 Nov;123(11):1644-1655
Deficiency of pseudogene UPAT leads to hepatocellular carcinoma progression and forms a positive feedback loop with ZEB1.
Xiang L, Huang X, Wang S, Ou H, Chen Z, Hu Z, Huang Y, Li X, Yuan Y, Yang D
Cancer science 2020 Nov;111(11):4102-4117
Cancer science 2020 Nov;111(11):4102-4117
Exosome-derived ENO1 regulates integrin α6β4 expression and promotes hepatocellular carcinoma growth and metastasis.
Jiang K, Dong C, Yin Z, Li R, Mao J, Wang C, Zhang J, Gao Z, Liang R, Wang Q, Wang L
Cell death & disease 2020 Nov 12;11(11):972
Cell death & disease 2020 Nov 12;11(11):972
Serum KIAA1199 is an advanced-stage prognostic biomarker and metastatic oncogene in cholangiocarcinoma.
Zhai X, Wang W, Ma Y, Zeng Y, Dou D, Fan H, Song J, Yu X, Xin D, Du G, Jiang Z, Zhang H, Zhang X, Jin B
Aging 2020 Nov 10;12(23):23761-23777
Aging 2020 Nov 10;12(23):23761-23777
Sirtuin 6 attenuates epithelial-mesenchymal transition by suppressing the TGF-β1/Smad3 pathway and c-Jun in asthma models.
Liu F, Shang YX
International immunopharmacology 2020 May;82:106333
International immunopharmacology 2020 May;82:106333
FGD1 exhibits oncogenic properties in hepatocellular carcinoma through regulating cell morphology, autophagy and mitochondrial function.
Zeng Y, Guo Z, Hu Z, Liu M, Chen Y, Chen S, Peng B, Zhang P, Wu Z, Luo H, Zhong F, Jiang K, Lu Y, Yuan G, He S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:110029
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:110029
BMP8A promotes survival and drug resistance via Nrf2/TRIM24 signaling pathway in clear cell renal cell carcinoma.
Yu YP, Cai LC, Wang XY, Cheng SY, Zhang DM, Jian WG, Wang TD, Yang JK, Yang KB, Zhang C
Cancer science 2020 May;111(5):1555-1566
Cancer science 2020 May;111(5):1555-1566
The roles of dipeptidyl peptidase-4 and its inhibitors in the regulation of airway epithelial-mesenchymal transition.
Sun J, Chu S, Lu M, Pan Q, Li D, Zheng S, Ma L
Experimental lung research 2020 May-Aug;46(6):163-173
Experimental lung research 2020 May-Aug;46(6):163-173
PHLDA2 regulates EMT and autophagy in colorectal cancer via the PI3K/AKT signaling pathway.
Ma Z, Lou S, Jiang Z
Aging 2020 May 8;12(9):7985-8000
Aging 2020 May 8;12(9):7985-8000
IMPDH1/YB-1 Positive Feedback Loop Assembles Cytoophidia and Represents a Therapeutic Target in Metastatic Tumors.
Ruan H, Song Z, Cao Q, Ni D, Xu T, Wang K, Bao L, Tong J, Xiao H, Xiao W, Cheng G, Xiong Z, Liang H, Liu D, Wang L, Olivier T, Jane BH, Yang H, Zhang X, Chen K
Molecular therapy : the journal of the American Society of Gene Therapy 2020 May 6;28(5):1299-1313
Molecular therapy : the journal of the American Society of Gene Therapy 2020 May 6;28(5):1299-1313
Downregulation of GLYR1 contributes to microsatellite instability colorectal cancer by targeting p21 via the p38MAPK and PI3K/AKT pathways.
Hu Z, Long T, Ma Y, Zhu J, Gao L, Zhong Y, Wang X, Wang X, Li Z
Journal of experimental & clinical cancer research : CR 2020 May 5;39(1):76
Journal of experimental & clinical cancer research : CR 2020 May 5;39(1):76
MAY, a novel tubulin inhibitor, induces cell apoptosis in A549 and A549/Taxol cells and inhibits epithelial-mesenchymal transition in A549/Taxol cells.
Du J, Li J, Gao M, Guan Q, Liu T, Wu Y, Li Z, Zuo D, Zhang W, Wu Y
Chemico-biological interactions 2020 May 25;323:109074
Chemico-biological interactions 2020 May 25;323:109074
Bioinformatic analysis reveals the importance of epithelial-mesenchymal transition in the development of endometriosis.
Chen M, Zhou Y, Xu H, Hill C, Ewing RM, He D, Zhang X, Wang Y
Scientific reports 2020 May 21;10(1):8442
Scientific reports 2020 May 21;10(1):8442
MS-275 combined with cisplatin exerts synergistic antitumor effects in human esophageal squamous cell carcinoma cells.
Liu T, Guan F, Wang Y, Zhang Z, Li Y, Cui Y, Li Z, Liu H, Zhang Y, Wang Y, Ma S
Toxicology and applied pharmacology 2020 May 15;395:114971
Toxicology and applied pharmacology 2020 May 15;395:114971
A dual receptors-targeting and size-switchable "cluster bomb" co-loading chemotherapeutic and transient receptor potential ankyrin 1 (TRPA-1) inhibitor for treatment of triple negative breast cancer.
Wang Y, Yin S, Mei L, Yang Y, Xu S, He X, Wang M, Li M, Zhang Z, He Q
Journal of controlled release : official journal of the Controlled Release Society 2020 May 10;321:71-83
Journal of controlled release : official journal of the Controlled Release Society 2020 May 10;321:71-83
MiR-328-3p inhibits cell proliferation and metastasis in colorectal cancer by targeting Girdin and inhibiting the PI3K/Akt signaling pathway.
Pan S, Ren F, Li L, Liu D, Li Y, Wang A, Li W, Dong Y, Guo W
Experimental cell research 2020 May 1;390(1):111939
Experimental cell research 2020 May 1;390(1):111939
An Amino Acid-Based Oral Rehydration Solution Regulates Radiation-Induced Intestinal Barrier Disruption in Mice.
Gupta R, Yin L, Grosche A, Lin S, Xu X, Guo J, Vaught LA, Okunieff PG, Vidyasagar S
The Journal of nutrition 2020 May 1;150(5):1100-1108
The Journal of nutrition 2020 May 1;150(5):1100-1108
PLEK2 mediates metastasis and vascular invasion via the ubiquitin-dependent degradation of SHIP2 in non-small cell lung cancer.
Wu DM, Deng SH, Zhou J, Han R, Liu T, Zhang T, Li J, Chen JP, Xu Y
International journal of cancer 2020 May 1;146(9):2563-2575
International journal of cancer 2020 May 1;146(9):2563-2575
Downregulated placental expression of linc00468 contributes to trophoblast dysfunction by inducing epithelial-mesenchymal transition.
Wang S, Wu D, Xu Y, Cao Y, Wang J, Zhang Y, Yang N, Sun L
Annals of translational medicine 2020 Mar;8(6):333
Annals of translational medicine 2020 Mar;8(6):333
The Mutational Features of Aristolochic Acid-Induced Mouse and Human Liver Cancers.
Lu ZN, Luo Q, Zhao LN, Shi Y, Wang N, Wang L, Han ZG
Hepatology (Baltimore, Md.) 2020 Mar;71(3):929-942
Hepatology (Baltimore, Md.) 2020 Mar;71(3):929-942
Rosmarinic acid exerts an anticancer effect on osteosarcoma cells by inhibiting DJ-1 via regulation of the PTEN-PI3K-Akt signaling pathway.
Ma Z, Yang J, Yang Y, Wang X, Chen G, Shi A, Lu Y, Jia S, Kang X, Lu L
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Mar;68:153186
Phytomedicine : international journal of phytotherapy and phytopharmacology 2020 Mar;68:153186
Resveratrol protects the integrity of alveolar epithelial barrier via SIRT1/PTEN/p-Akt pathway in methamphetamine-induced chronic lung injury.
Wang X, Liu M, Zhu MJ, Shi L, Liu L, Zhao YL, Cheng L, Gu YJ, Zhou MY, Chen L, Kumar A, Wang Y
Cell proliferation 2020 Mar;53(3):e12773
Cell proliferation 2020 Mar;53(3):e12773
LncRNA PTCSC3 inhibits the proliferation, invasion and migration of cervical cancer cells via sponging miR-574-5p.
Tong R, Zhang J, Wang C, Li X, Yu T, Wang L
Clinical and experimental pharmacology & physiology 2020 Mar;47(3):439-448
Clinical and experimental pharmacology & physiology 2020 Mar;47(3):439-448
Linc00261 inhibits metastasis and the WNT signaling pathway of pancreatic cancer by regulating a miR‑552‑5p/FOXO3 axis.
Chen T, Lei S, Zeng Z, Zhang J, Xue Y, Sun Y, Lan J, Xu S, Mao D, Guo B
Oncology reports 2020 Mar;43(3):930-942
Oncology reports 2020 Mar;43(3):930-942
Interleukin 1β/1RA axis in colorectal cancer regulates tumor invasion, proliferation and apoptosis via autophagy.
Chen Y, Yang Z, Deng B, Wu D, Quan Y, Min Z
Oncology reports 2020 Mar;43(3):908-918
Oncology reports 2020 Mar;43(3):908-918
Cyclovirobuxine D Exerts Anticancer Effects by Suppressing the EGFR-FAK-AKT/ERK1/2-Slug Signaling Pathway in Human Hepatocellular Carcinoma.
Zhang J, Chen Y, Lin J, Jia R, An T, Dong T, Zhang Y, Yang X
DNA and cell biology 2020 Mar;39(3):355-367
DNA and cell biology 2020 Mar;39(3):355-367
microRNA-141 inhibits TGF-β1-induced epithelial-to-mesenchymal transition through inhibition of the TGF-β1/SMAD2 signalling pathway in endometriosis.
Wang S, Zhang M, Zhang T, Deng J, Xia X, Fang X
Archives of gynecology and obstetrics 2020 Mar;301(3):707-714
Archives of gynecology and obstetrics 2020 Mar;301(3):707-714
LncRNA MALAT1 knockdown inhibits cell migration and invasion by suppressing autophagy through miR-384/GOLM1 axis in glioma.
Ma R, Zhang BW, Zhang ZB, Deng QJ
European review for medical and pharmacological sciences 2020 Mar;24(5):2601-2615
European review for medical and pharmacological sciences 2020 Mar;24(5):2601-2615
Decreasing New York esophageal squamous cell carcinoma 1 expression inhibits multiple myeloma growth and osteolytic lesions.
Li F, Zhao F, Li M, Pan M, Shi F, Xu H, Zheng D, Wang L, Dou J
Journal of cellular physiology 2020 Mar;235(3):2183-2194
Journal of cellular physiology 2020 Mar;235(3):2183-2194
ROS/p53/miR‑335‑5p/Sp1 axis modulates the migration and epithelial to mesenchymal transition of JEG‑3 cells.
Lu W, Ma YY, Shao QQ, Liang J, Qi TT, Huang Y, Wang QJ
Molecular medicine reports 2020 Mar;21(3):1208-1216
Molecular medicine reports 2020 Mar;21(3):1208-1216
The mechanism of PDA/PEI/5-Fu coated esophageal stent material on inhibiting cancer associated pathological cells.
Zhang K, Bai Y, Xu R, Li J, Guan F
Journal of biomedical materials research. Part A 2020 Mar;108(3):814-821
Journal of biomedical materials research. Part A 2020 Mar;108(3):814-821
Hepatocarcinoma-intestine-pancreas/pancreatitis-associated protein (HIP/PAP) confers protection against hepatic fibrosis through downregulation of transforming growth factor β receptor II.
Li Q, Li H, Lv Y, Zhang Q, Zhang X, Li S, Zheng X, Wang Y, Hao Z
Laboratory investigation; a journal of technical methods and pathology 2020 Mar;100(3):466-482
Laboratory investigation; a journal of technical methods and pathology 2020 Mar;100(3):466-482
Novel HSP90-PI3K Dual Inhibitor Suppresses Melanoma Cell Proliferation by Interfering with HSP90-EGFR Interaction and Downstream Signaling Pathways.
Zhao Q, Zhu HP, Xie X, Mao Q, Liu YQ, He XH, Peng C, Jiang QL, Huang W
International journal of molecular sciences 2020 Mar 7;21(5)
International journal of molecular sciences 2020 Mar 7;21(5)
Retinol-Binding Protein 4 Accelerates Metastatic Spread and Increases Impairment of Blood Flow in Mouse Mammary Gland Tumors.
Papiernik D, Urbaniak A, Kłopotowska D, Nasulewicz-Goldeman A, Ekiert M, Nowak M, Jarosz J, Cuprych M, Strzykalska A, Ugorski M, Matkowski R, Wietrzyk J
Cancers 2020 Mar 7;12(3)
Cancers 2020 Mar 7;12(3)
Transcription co-activator P300 activates Elk1-aPKC-ι signaling mediated epithelial-to-mesenchymal transition and malignancy in hepatocellular carcinoma.
Ma C, Huang S, Xu L, Tian L, Yang Y, Wang J
Oncogenesis 2020 Mar 6;9(3):32
Oncogenesis 2020 Mar 6;9(3):32
Long non-coding RNA HAL suppresses the migration and invasion of serous ovarian cancer by inhibiting EMT signaling pathway.
Wu K, Li L, Li L, Wang D
Bioscience reports 2020 Mar 27;40(3)
Bioscience reports 2020 Mar 27;40(3)
Tartrate-Resistant Acid Phosphatase 5/ACP5 Interacts with p53 to Control the Expression of SMAD3 in Lung Adenocarcinoma.
Hu Y, Yu J, Wang Q, Zhang L, Chen X, Cao Y, Zhao J, Xu Y, Jiang D, Wang Y, Xiong W
Molecular therapy oncolytics 2020 Mar 27;16:272-288
Molecular therapy oncolytics 2020 Mar 27;16:272-288
XIAOPI formula inhibits the pre-metastatic niche formation in breast cancer via suppressing TAMs/CXCL1 signaling.
Zheng Y, Wang N, Wang S, Yang B, Situ H, Zhong L, Lin Y, Wang Z
Cell communication and signaling : CCS 2020 Mar 26;18(1):48
Cell communication and signaling : CCS 2020 Mar 26;18(1):48
CD73 promotes tumor metastasis by modulating RICS/RhoA signaling and EMT in gastric cancer.
Xu Z, Gu C, Yao X, Guo W, Wang H, Lin T, Li F, Chen D, Wu J, Ye G, Zhao L, Hu Y, Yu J, Shi J, Li G, Liu H
Cell death & disease 2020 Mar 23;11(3):202
Cell death & disease 2020 Mar 23;11(3):202
Mutations in the coat complex II component SEC23B promote colorectal cancer metastasis.
Yang C, Chen N, Li X, Lu D, Hou Z, Li Y, Jin Y, Gu J, Yin Y
Cell death & disease 2020 Mar 2;11(3):157
Cell death & disease 2020 Mar 2;11(3):157
HBXIP: a potential prognosis biomarker of colorectal cancer which promotes invasion and migration via epithelial-mesenchymal transition.
Wang X, Feng Q, Yu H, Zhou X, Shan C, Zhang Q, Liu S
Life sciences 2020 Mar 15;245:117354
Life sciences 2020 Mar 15;245:117354
A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3-PBX1 and β-catenin-ABCG2 signaling.
Fang CH, Lin YT, Liang CM, Liang SM
Journal of biomedical science 2020 Mar 13;27(1):42
Journal of biomedical science 2020 Mar 13;27(1):42
HOXD9 promote epithelial-mesenchymal transition and metastasis in colorectal carcinoma.
Liu M, Xiao Y, Tang W, Li J, Hong L, Dai W, Zhang W, Peng Y, Wu X, Wang J, Chen Y, Bai Y, Lin J, Yang Q, Wang Y, Lin Z, Liu S, Xiong J, Wang J, Xiang L
Cancer medicine 2020 Jun;9(11):3932-3943
Cancer medicine 2020 Jun;9(11):3932-3943
MicroRNA‑500a‑5p inhibits colorectal cancer cell invasion and epithelial‑mesenchymal transition.
Tang W, Hong L, Dai W, Li J, Zhu H, Lin J, Yang Q, Wang Y, Lin Z, Liu M, Xiao Y, Zhang Y, Wu X, Wang J, Chen Y, Hu H, Liu S, Wang J, Xiang L
International journal of oncology 2020 Jun;56(6):1499-1508
International journal of oncology 2020 Jun;56(6):1499-1508
Upregulated NTF4 in colorectal cancer promotes tumor development via regulating autophagy.
Yang Z, Chen Y, Wei X, Wu D, Min Z, Quan Y
International journal of oncology 2020 Jun;56(6):1442-1454
International journal of oncology 2020 Jun;56(6):1442-1454
Inhibition of miR-574-5p suppresses cell growth and metastasis and enhances chemosensitivity by targeting RNA binding protein QKI in cervical cancer cells.
Tong R, Zhang J, Wang C, Li Q, Wang L, Ju M
Naunyn-Schmiedeberg's archives of pharmacology 2020 Jun;393(6):951-966
Naunyn-Schmiedeberg's archives of pharmacology 2020 Jun;393(6):951-966
Anti-human serum albumin autoantibody may be involved in the pathogenesis of autoimmune bullous skin diseases.
Qian H, Cao Y, Sun J, Zu J, Ma L, Zhou H, Tang X, Li Y, Yu H, Zhang M, Bai Y, Xu C, Ishii N, Hashimoto T, Li X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):8574-8595
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jun;34(6):8574-8595
Effect of STAT3 mediated epigenetic regulation in pre-eclampsia: an analysis of trial data.
Zhang XL, Pan J, Wang G, Li H, Wang JL, Jiang XM, Zhao XY
European review for medical and pharmacological sciences 2020 Jun;24(11):5843-5855
European review for medical and pharmacological sciences 2020 Jun;24(11):5843-5855
Extracellular vesicles produced by bone marrow mesenchymal stem cells attenuate renal fibrosis, in part by inhibiting the RhoA/ROCK pathway, in a UUO rat model.
Shi Z, Wang Q, Zhang Y, Jiang D
Stem cell research & therapy 2020 Jun 26;11(1):253
Stem cell research & therapy 2020 Jun 26;11(1):253
Klotho is regulated by transcription factor Sp1 in renal tubular epithelial cells.
Li Y, Liu Y, Wang K, Huang Y, Han W, Xiong J, Yang K, Liu M, Xiao T, Liu C, He T, Bi X, Zhang J, Zhang B, Zhao J
BMC molecular and cell biology 2020 Jun 22;21(1):45
BMC molecular and cell biology 2020 Jun 22;21(1):45
M6A-related bioinformatics analysis reveals that HNRNPC facilitates progression of OSCC via EMT.
Huang GZ, Wu QQ, Zheng ZN, Shao TR, Chen YC, Zeng WS, Lv XZ
Aging 2020 Jun 11;12(12):11667-11684
Aging 2020 Jun 11;12(12):11667-11684
ARHGEF10L expression regulates cell proliferation and migration in gastric tumorigenesis.
Wang DW, Tang JY, Zhang GQ, Chang XT
Bioscience, biotechnology, and biochemistry 2020 Jul;84(7):1362-1372
Bioscience, biotechnology, and biochemistry 2020 Jul;84(7):1362-1372
Cyclovirobuxine D inhibits colorectal cancer tumorigenesis via the CTHRC1‑AKT/ERK‑Snail signaling pathway.
Jiang F, Chen Y, Ren S, Li Z, Sun K, Xing Y, Zhu Y, Piao D
International journal of oncology 2020 Jul;57(1):183-196
International journal of oncology 2020 Jul;57(1):183-196
PCNP promotes ovarian cancer progression by accelerating β-catenin nuclear accumulation and triggering EMT transition.
Dong P, Fu H, Chen L, Zhang S, Zhang X, Li H, Wu D, Ji X
Journal of cellular and molecular medicine 2020 Jul;24(14):8221-8235
Journal of cellular and molecular medicine 2020 Jul;24(14):8221-8235
The effect of lncRNA-ARAP1-AS2/ARAP1 on high glucose-induced cytoskeleton rearrangement and epithelial-mesenchymal transition in human renal tubular epithelial cells.
Li L, Xu L, Wen S, Yang Y, Li X, Fan Q
Journal of cellular physiology 2020 Jul;235(7-8):5787-5795
Journal of cellular physiology 2020 Jul;235(7-8):5787-5795
LncRNA MALAT1 affects the migration and invasion of trophoblast cells by regulating FOS expression in early-onset preeclampsia.
Li Q, Wang T, Huang S, Zuo Q, Jiang Z, Yang N, Sun L
Pregnancy hypertension 2020 Jul;21:50-57
Pregnancy hypertension 2020 Jul;21:50-57
miR-96-5p regulated TGF-β/SMAD signaling pathway and suppressed endometrial cell viability and migration via targeting TGFBR1.
Chen S, Luo Y, Cui L, Yang Q
Cell cycle (Georgetown, Tex.) 2020 Jul;19(14):1740-1753
Cell cycle (Georgetown, Tex.) 2020 Jul;19(14):1740-1753
Alteration of N(6)-methyladenosine epitranscriptome profile in unilateral ureteral obstructive nephropathy.
Li X, Fan X, Yin X, Liu H, Yang Y
Epigenomics 2020 Jul;12(14):1157-1173
Epigenomics 2020 Jul;12(14):1157-1173
PD-L1 promotes tumor growth and progression by activating WIP and β-catenin signaling pathways and predicts poor prognosis in lung cancer.
Yu W, Hua Y, Qiu H, Hao J, Zou K, Li Z, Hu S, Guo P, Chen M, Sui S, Xiong Y, Li F, Lu J, Guo W, Luo G, Deng W
Cell death & disease 2020 Jul 6;11(7):506
Cell death & disease 2020 Jul 6;11(7):506
CD147 promotes collective invasion through cathepsin B in hepatocellular carcinoma.
Wang SJ, Chao D, Wei W, Nan G, Li JY, Liu FL, Li L, Jiang JL, Cui HY, Chen ZN
Journal of experimental & clinical cancer research : CR 2020 Jul 29;39(1):145
Journal of experimental & clinical cancer research : CR 2020 Jul 29;39(1):145
The cross-talk between DDR1 and STAT3 promotes the development of hepatocellular carcinoma.
Lin Y, Jin H, Wu X, Jian Z, Zou X, Huang J, Guan R, Wei X
Aging 2020 Jul 27;12(14):14391-14405
Aging 2020 Jul 27;12(14):14391-14405
Long noncoding RNA MAPKAPK5-AS1 promotes colorectal cancer progression by cis-regulating the nearby gene MK5 and acting as a let-7f-1-3p sponge.
Yang T, Chen WC, Shi PC, Liu MR, Jiang T, Song H, Wang JQ, Fan RZ, Pei DS, Song J
Journal of experimental & clinical cancer research : CR 2020 Jul 20;39(1):139
Journal of experimental & clinical cancer research : CR 2020 Jul 20;39(1):139
Targeted delivery of honokiol by zein/hyaluronic acid core-shell nanoparticles to suppress breast cancer growth and metastasis.
Zhang Q, Wang J, Liu D, Zhu W, Guan S, Fan L, Cai D
Carbohydrate polymers 2020 Jul 15;240:116325
Carbohydrate polymers 2020 Jul 15;240:116325
Echinatin suppresses esophageal cancer tumor growth and invasion through inducing AKT/mTOR-dependent autophagy and apoptosis.
Hong P, Liu QW, Xie Y, Zhang QH, Liao L, He QY, Li B, Xu WW
Cell death & disease 2020 Jul 13;11(7):524
Cell death & disease 2020 Jul 13;11(7):524
CPEB3 inhibits epithelial-mesenchymal transition by disrupting the crosstalk between colorectal cancer cells and tumor-associated macrophages via IL-6R/STAT3 signaling.
Zhong Q, Fang Y, Lai Q, Wang S, He C, Li A, Liu S, Yan Q
Journal of experimental & clinical cancer research : CR 2020 Jul 11;39(1):132
Journal of experimental & clinical cancer research : CR 2020 Jul 11;39(1):132
Sini San ameliorates duodenal mucosal barrier injury and low‑grade inflammation via the CRF pathway in a rat model of functional dyspepsia.
Zhu C, Zhao L, Zhao J, Zhang S
International journal of molecular medicine 2020 Jan;45(1):53-60
International journal of molecular medicine 2020 Jan;45(1):53-60
Long non‑coding RNA HCP5 promotes prostate cancer cell proliferation by acting as the sponge of miR‑4656 to modulate CEMIP expression.
Hu R, Lu Z
Oncology reports 2020 Jan;43(1):328-336
Oncology reports 2020 Jan;43(1):328-336
Subcellular trafficking of tubular MDM2 implicates in acute kidney injury to chronic kidney disease transition during multiple low-dose cisplatin exposure.
Su H, Ye C, Lei CT, Tang H, Zeng JY, Yi F, Zhang C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1620-1636
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1620-1636
MiR-490-5p functions as tumor suppressor in childhood neuroblastoma by targeting MYEOV.
Wang J, Zhang X, Yao H, Le Y, Zhou W, Li J, Lu L, Chen M, Li X
Human cell 2020 Jan;33(1):261-271
Human cell 2020 Jan;33(1):261-271
Spondin 2 promotes the proliferation, migration and invasion of gastric cancer cells.
Lu H, Feng Y, Hu Y, Guo Y, Liu Y, Mao Q, Xue W
Journal of cellular and molecular medicine 2020 Jan;24(1):98-113
Journal of cellular and molecular medicine 2020 Jan;24(1):98-113
Hydroxypropyl‑β‑cyclodextrin attenuates the epithelial‑to‑mesenchymal transition via endoplasmic reticulum stress in MDA‑MB‑231 breast cancer cells.
Wu Y, Zhao Y, He X, He Z, Wang T, Wan L, Chen L, Yan N
Molecular medicine reports 2020 Jan;21(1):249-257
Molecular medicine reports 2020 Jan;21(1):249-257
Norepinephrine transporter promotes the invasion of human colon cancer cells.
Zhang H, Miao J, Li F, Xue W, Tang K, Zhao X, Jing X, Zhang J, Huang C, Hou N, Han J
Oncology letters 2020 Jan;19(1):824-832
Oncology letters 2020 Jan;19(1):824-832
The anti-migration and anti-invasion effects of Bruceine D in human triple-negative breast cancer MDA-MB-231 cells.
Luo C, Wang Y, Wei C, Chen Y, Ji Z
Experimental and therapeutic medicine 2020 Jan;19(1):273-279
Experimental and therapeutic medicine 2020 Jan;19(1):273-279
Long noncoding RNA CASC21 exerts an oncogenic role in colorectal cancer through regulating miR-7-5p/YAP1 axis.
Zheng Y, Nie P, Xu S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109628
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109628
Resveratrol induces depletion of TRAF6 and suppresses prostate cancer cell proliferation and migration.
Khusbu FY, Zhou X, Roy M, Chen FZ, Cao Q, Chen HC
The international journal of biochemistry & cell biology 2020 Jan;118:105644
The international journal of biochemistry & cell biology 2020 Jan;118:105644
Upregulation of E-cadherin in bronchoalveolar lavage fluid-derived exosomes in patients with lung cancer.
Zhang Y, Liu Z, Li S, Wang M, Dai D, Jing H, Liu L
Thoracic cancer 2020 Jan;11(1):41-47
Thoracic cancer 2020 Jan;11(1):41-47
Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer.
Ma J, Qi J, Li S, Zhang C, Wang H, Shao L, Yuan X, Sha Q
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820926591
Technology in cancer research & treatment 2020 Jan-Dec;19:1533033820926591
Graphene Oxide Causes Disordered Zonation Due to Differential Intralobular Localization in the Liver.
Wu Y, Feng W, Liu R, Xia T, Liu S
ACS nano 2020 Jan 28;14(1):877-890
ACS nano 2020 Jan 28;14(1):877-890
Graphene Oxide Promotes Cancer Metastasis through Associating with Plasma Membrane To Promote TGF-β Signaling-Dependent Epithelial-Mesenchymal Transition.
Zhu J, Li B, Xu M, Liu R, Xia T, Zhang Z, Xu Y, Liu S
ACS nano 2020 Jan 28;14(1):818-827
ACS nano 2020 Jan 28;14(1):818-827
Telmisartan inhibits oxalate and calcium oxalate crystal-induced epithelial-mesenchymal transformation via PPAR-γ-AKT/STAT3/p38 MAPK-Snail pathway.
Liu Y, Chen S, Liu J, Jin Y, Yu S, An R
Life sciences 2020 Jan 15;241:117108
Life sciences 2020 Jan 15;241:117108
FHL3 promotes pancreatic cancer invasion and metastasis through preventing the ubiquitination degradation of EMT associated transcription factors.
Li P, Cao G, Zhang Y, Shi J, Cai K, Zhen L, He X, Zhou Y, Li Y, Zhu Y, Xiong M, Wu Y
Aging 2020 Jan 13;12(1):53-69
Aging 2020 Jan 13;12(1):53-69
A super-enhancer controls TGF- β signaling in pancreatic cancer through downregulation of TGFBR2.
Zhu X, Zhang T, Zhang Y, Chen H, Shen J, Jin X, Wei J, Zhang E, Xiao M, Fan Y, Mao R, Zhou G
Cellular signalling 2020 Feb;66:109470
Cellular signalling 2020 Feb;66:109470
CCND1, NOP14 and DNMT3B are involved in miR-502-5p-mediated inhibition of cell migration and proliferation in bladder cancer.
Ying Y, Li J, Xie H, Yan H, Jin K, He L, Ma X, Wu J, Xu X, Fang J, Wang X, Zheng X, Liu B, Xie L
Cell proliferation 2020 Feb;53(2):e12751
Cell proliferation 2020 Feb;53(2):e12751
Epiregulin promotes trophoblast epithelial-mesenchymal transition through poFUT1 and O-fucosylation by poFUT1 on uPA.
Cui X, Wang H, Li Y, Chen T, Liu S, Yan Q
Cell proliferation 2020 Feb;53(2):e12745
Cell proliferation 2020 Feb;53(2):e12745
eIF4E‑related miR‑320a and miR‑340‑5p inhibit endometrial carcinoma cell metastatic capability by preventing TGF‑β1‑induced epithelial‑mesenchymal transition.
Zhang HH, Li R, Li YJ, Yu XX, Sun QN, Li AY, Kong Y
Oncology reports 2020 Feb;43(2):447-460
Oncology reports 2020 Feb;43(2):447-460
miR-1294 alleviates epithelial-mesenchymal transition by repressing FOXK1 in gastric cancer.
Wang Y, Liu G, Sun S, Qin J
Genes & genomics 2020 Feb;42(2):217-224
Genes & genomics 2020 Feb;42(2):217-224
The reciprocal interaction between tumor cells and activated fibroblasts mediated by TNF-α/IL-33/ST2L signaling promotes gastric cancer metastasis.
Zhou Q, Wu X, Wang X, Yu Z, Pan T, Li Z, Chang X, Jin Z, Li J, Zhu Z, Liu B, Su L
Oncogene 2020 Feb;39(7):1414-1428
Oncogene 2020 Feb;39(7):1414-1428
Berberine inhibits proliferation and migration of colorectal cancer cells by downregulation of GRP78.
Gong C, Hu X, Xu Y, Yang J, Zong L, Wang C, Zhu J, Li Z, Lu D
Anti-cancer drugs 2020 Feb;31(2):141-149
Anti-cancer drugs 2020 Feb;31(2):141-149
Protocatechuic Aldehyde Represses Proliferation and Migration of Breast Cancer Cells through Targeting C-terminal Binding Protein 1.
Deng Y, Guo W, Li G, Li S, Li H, Li X, Niu B, Song M, Zhang Y, Xu Z, Li F
Journal of breast cancer 2020 Feb;23(1):20-35
Journal of breast cancer 2020 Feb;23(1):20-35
Expression and clinical significance of WWOX, Elf5, Snail1 and EMT related factors in epithelial ovarian cancer.
Hu Y, Yan Y, Xu Y, Yang H, Fang L, Liu Y, Li X, Li Q, Yan H
Oncology letters 2020 Feb;19(2):1281-1290
Oncology letters 2020 Feb;19(2):1281-1290
PLAGL2 promotes epithelial-mesenchymal transition and mediates colorectal cancer metastasis via β-catenin-dependent regulation of ZEB1.
Wu L, Zhou Z, Han S, Chen J, Liu Z, Zhang X, Yuan W, Ji J, Shu X
British journal of cancer 2020 Feb;122(4):578-589
British journal of cancer 2020 Feb;122(4):578-589
The lncRNA FEZF1-AS1 Promotes the Progression of Colorectal Cancer Through Regulating OTX1 and Targeting miR-30a-5p.
Li J, Zhao LM, Zhang C, Li M, Gao B, Hu XH, Cao J, Wang GY
Oncology research 2020 Feb 7;28(1):51-63
Oncology research 2020 Feb 7;28(1):51-63
Knockdown of P3H4 inhibits proliferation and invasion of bladder cancer.
Hao L, Pang K, Pang H, Zhang J, Zhang Z, He H, Zhou R, Shi Z, Han C
Aging 2020 Feb 4;12(3):2156-2168
Aging 2020 Feb 4;12(3):2156-2168
Antisense lncRNA LDLRAD4-AS1 promotes metastasis by decreasing the expression of LDLRAD4 and predicts a poor prognosis in colorectal cancer.
Mo S, Zhang L, Dai W, Han L, Wang R, Xiang W, Wang Z, Li Q, Yu J, Yuan J, Cai S, Cai G
Cell death & disease 2020 Feb 28;11(2):155
Cell death & disease 2020 Feb 28;11(2):155
SERPINH1 regulates EMT and gastric cancer metastasis via the Wnt/β-catenin signaling pathway.
Tian S, Peng P, Li J, Deng H, Zhan N, Zeng Z, Dong W
Aging 2020 Feb 24;12(4):3574-3593
Aging 2020 Feb 24;12(4):3574-3593
Interaction of calcium binding protein S100A16 with myosin-9 promotes cytoskeleton reorganization in renal tubulointerstitial fibrosis.
Sun H, Zhao A, Li M, Dong H, Sun Y, Zhang X, Zhu Q, Bukhari AA, Cao C, Su D, Liu Y, Liang X
Cell death & disease 2020 Feb 24;11(2):146
Cell death & disease 2020 Feb 24;11(2):146
GRWD1 promotes cell proliferation and migration in non-small cell lung cancer by activating the Notch pathway.
Wang Q, Ren H, Xu Y, Jiang J, Wudu M, Liu Z, Su H, Jiang X, Zhang Y, Zhang B, Qiu X
Experimental cell research 2020 Feb 15;387(2):111806
Experimental cell research 2020 Feb 15;387(2):111806
TMEFF2 is a novel prognosis signature and target for endometrial carcinoma.
Gao L, Nie X, Zheng M, Li X, Guo Q, Liu J, Liu Q, Hao Y, Lin B
Life sciences 2020 Feb 15;243:116910
Life sciences 2020 Feb 15;243:116910
IL-6 trans-signaling drives a STAT3-dependent pathway that leads to structural alterations of the peritoneal membrane.
Yang X, Yan H, Jiang N, Yu Z, Yuan J, Ni Z, Fang W
American journal of physiology. Renal physiology 2020 Feb 1;318(2):F338-F353
American journal of physiology. Renal physiology 2020 Feb 1;318(2):F338-F353
YAP activity protects against endotoxemic acute lung injury by activating multiple mechanisms.
Liu LY, Shan XQ, Zhang FK, Fan XF, Fan JM, Wang YY, Liu SF, Mao SZ, Gong YS
International journal of molecular medicine 2020 Dec;46(6):2235-2250
International journal of molecular medicine 2020 Dec;46(6):2235-2250
The POU2F1/miR-4490/USP22 axis regulates cell proliferation and metastasis in gastric cancer.
Xiao Y, Liu S, Li J, Dai W, Tang W, Xiang L, Zhang W, Lin J, Wang J, Wu X, Liu G, Liu Y, Chen Y, Zhu H, Wang Y, Lin Z, Yang Q, Chen T, Sun Y, Li A, Xiong J, Wang J
Cellular oncology (Dordrecht, Netherlands) 2020 Dec;43(6):1017-1033
Cellular oncology (Dordrecht, Netherlands) 2020 Dec;43(6):1017-1033
Promotion of esophageal adenocarcinoma metastasis via Wnt/ß-catenin signal pathway by sorting nexins 3.
Pan B, Liu L, Hu X, Sun X, Zhu Y, Zhang T, Wei D, Guo Y, Shan J
Journal of gastroenterology and hepatology 2020 Dec;35(12):2131-2139
Journal of gastroenterology and hepatology 2020 Dec;35(12):2131-2139
Circ_0075829 facilitates the progression of pancreatic carcinoma by sponging miR-1287-5p and activating LAMTOR3 signalling.
Zhang X, Xue C, Cui X, Zhou Z, Fu Y, Yin X, Wu S, Gong Y, Liu Y, Zhu C, Qin X
Journal of cellular and molecular medicine 2020 Dec;24(24):14596-14607
Journal of cellular and molecular medicine 2020 Dec;24(24):14596-14607
Chinese herbal formula QHF inhibits hepatocellular carcinoma metastasis via HGF/c-Met signaling pathway.
Yuan S, Gong Y, Chen R, Du J, Zhang H, Chen T
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Dec;132:110867
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Dec;132:110867
Down-regulation of lncRNA DNAJC3-AS1 inhibits colon cancer via regulating miR-214-3p/LIVIN axis.
Han B, Ge Y, Cui J, Liu B
Bioengineered 2020 Dec;11(1):524-535
Bioengineered 2020 Dec;11(1):524-535
Long non-coding RNA PHACTR2-AS1 promotes tongue squamous cell carcinoma metastasis by regulating Snail.
Yuan F, Miao Z, Chen W, Wu F, Wei C, Yong J, Xiao C
Journal of biochemistry 2020 Dec 26;168(6):651-657
Journal of biochemistry 2020 Dec 26;168(6):651-657
HOXB9 enhances the ability of lung cancer cells to penetrate the blood-brain barrier.
Zheng H, Li C, Li Z, Zhu K, Bao H, Xiong J, Liang P
Aging 2020 Dec 19;13(4):4999-5019
Aging 2020 Dec 19;13(4):4999-5019
High expression of RRM2 as an independent predictive factor of poor prognosis in patients with lung adenocarcinoma.
Jin CY, Du L, Nuerlan AH, Wang XL, Yang YW, Guo R
Aging 2020 Dec 19;13(3):3518-3535
Aging 2020 Dec 19;13(3):3518-3535
Regulation of FN1 degradation by the p62/SQSTM1-dependent autophagy-lysosome pathway in HNSCC.
Liu X, Meng L, Li X, Li D, Liu Q, Chen Y, Li X, Bu W, Sun H
International journal of oral science 2020 Dec 14;12(1):34
International journal of oral science 2020 Dec 14;12(1):34
The peptide mimicking small extracellular ring domain of CD82 inhibits epithelial-mesenchymal transition by downregulating Wnt pathway and upregulating hippo pathway.
He X, Huang X, Wang C, Luan M, Li Y, Ma X, Ma K
Biochemical and biophysical research communications 2020 Dec 10;533(3):338-345
Biochemical and biophysical research communications 2020 Dec 10;533(3):338-345
Podocyte-derived extracellular vesicles mediate renal proximal tubule cells dedifferentiation via microRNA-221 in diabetic nephropathy.
Su H, Qiao J, Hu J, Li Y, Lin J, Yu Q, Zhen J, Ma Q, Wang Q, Lv Z, Wang R
Molecular and cellular endocrinology 2020 Dec 1;518:111034
Molecular and cellular endocrinology 2020 Dec 1;518:111034
Silencing of the lncRNA TUG1 attenuates the epithelial-mesenchymal transition of renal tubular epithelial cells by sponging miR-141-3p via regulating β-catenin.
Zhang B, Zhao C, Hou L, Wu Y
American journal of physiology. Renal physiology 2020 Dec 1;319(6):F1125-F1134
American journal of physiology. Renal physiology 2020 Dec 1;319(6):F1125-F1134
BML-111 inhibits EMT, migration and metastasis of TAMs-stimulated triple-negative breast cancer cells via ILK pathway.
Lin L, Luo X, Wang L, Xu F, He Y, Wang Q, Yuan C, Xu J, Yan L, Hao H
International immunopharmacology 2020 Aug;85:106625
International immunopharmacology 2020 Aug;85:106625
The role of miR-34c-5p/Notch in epithelial-mesenchymal transition (EMT) in endometriosis.
Luo Y, Wang D, Chen S, Yang Q
Cellular signalling 2020 Aug;72:109666
Cellular signalling 2020 Aug;72:109666
Girdin interaction with vimentin induces EMT and promotes the growth and metastasis of pancreatic ductal adenocarcinoma.
Wang W, Chen H, Gao W, Wang S, Wu K, Lu C, Luo X, Li L, Yu C
Oncology reports 2020 Aug;44(2):637-649
Oncology reports 2020 Aug;44(2):637-649
Possible involvement of TGF‑β‑SMAD‑mediated epithelial‑mesenchymal transition in pro‑metastatic property of PAX6.
Jin M, Gao D, Wang R, Sik A, Liu K
Oncology reports 2020 Aug;44(2):555-564
Oncology reports 2020 Aug;44(2):555-564
Maladjustment of β-CGRP/α-CGRP Regulation of AQP5 Promotes Transition of Alveolar Epithelial Cell Apoptosis to Pulmonary Fibrosis.
Lv X, Gao F, Zhang S, Zhang S, Zhou X, Ding F, Wang J, Chen Q, Chen M, Liu Q
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2020 Aug;40(8):377-388
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2020 Aug;40(8):377-388
miR-143 inhibits renal cell carcinoma cells metastatic potential by suppressing ABL2.
Xu B, Wang C, Wang YL, Chen SQ, Wu JP, Zhu WD, Wang CY, Guan H, Guan C, You ZH, Chen M
The Kaohsiung journal of medical sciences 2020 Aug;36(8):592-598
The Kaohsiung journal of medical sciences 2020 Aug;36(8):592-598
Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer.
Liu D, Zhang H, Cui M, Chen C, Feng Y
Cell cycle (Georgetown, Tex.) 2020 Aug;19(15):1917-1927
Cell cycle (Georgetown, Tex.) 2020 Aug;19(15):1917-1927
FoxM1 inhibition ameliorates renal interstitial fibrosis by decreasing extracellular matrix and epithelial-mesenchymal transition.
Wang Y, Zhou Q, Tang R, Huang Y, He T
Journal of pharmacological sciences 2020 Aug;143(4):281-289
Journal of pharmacological sciences 2020 Aug;143(4):281-289
circ_0007385 served as competing endogenous RNA for miR-519d-3p to suppress malignant behaviors and cisplatin resistance of non-small cell lung cancer cells.
Ye Y, Zhao L, Li Q, Xi C, Li Y, Li Z
Thoracic cancer 2020 Aug;11(8):2196-2208
Thoracic cancer 2020 Aug;11(8):2196-2208
Reelin Promotes Cisplatin Resistance by Induction of Epithelial-Mesenchymal Transition via p38/GSK3β/Snail Signaling in Non-Small Cell Lung Cancer.
Li JM, Yang F, Li J, Yuan WQ, Wang H, Luo YQ
Medical science monitor : international medical journal of experimental and clinical research 2020 Aug 7;26:e925298
Medical science monitor : international medical journal of experimental and clinical research 2020 Aug 7;26:e925298
Hippuric Acid Promotes Renal Fibrosis by Disrupting Redox Homeostasis via Facilitation of NRF2-KEAP1-CUL3 Interactions in Chronic Kidney Disease.
Sun B, Wang X, Liu X, Wang L, Ren F, Wang X, Leng X
Antioxidants (Basel, Switzerland) 2020 Aug 25;9(9)
Antioxidants (Basel, Switzerland) 2020 Aug 25;9(9)
Role of exosomal microRNA-125b-5p in conferring the metastatic phenotype among pancreatic cancer cells with different potential of metastasis.
Wu M, Tan X, Liu P, Yang Y, Huang Y, Liu X, Meng X, Yu B, Wu Y, Jin H
Life sciences 2020 Aug 15;255:117857
Life sciences 2020 Aug 15;255:117857
MicroRNA-378-3p/5p suppresses the migration and invasiveness of oral squamous carcinoma cells by inhibiting KLK4 expression.
Cui Z, Sun S, Liu Q, Zhou X, Gao S, Peng P, Li Q
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Apr;98(2):154-163
Biochemistry and cell biology = Biochimie et biologie cellulaire 2020 Apr;98(2):154-163
Fangjihuangqi Decoction inhibits MDA-MB-231 cell invasion in vitro and decreases tumor growth and metastasis in triple-negative breast cancer xenografts tumor zebrafish model.
Guo Y, Fan Y, Pei X
Cancer medicine 2020 Apr;9(7):2564-2578
Cancer medicine 2020 Apr;9(7):2564-2578
LncRNA LINP1 confers tamoxifen resistance and negatively regulated by ER signaling in breast cancer.
Ma T, Liang Y, Li Y, Song X, Zhang N, Li X, Chen B, Zhao W, Wang L, Yang Q
Cellular signalling 2020 Apr;68:109536
Cellular signalling 2020 Apr;68:109536
GADD45G Interacts with E-cadherin to Suppress the Migration and Invasion of Esophageal Squamous Cell Carcinoma.
Li T, Xu L, Teng J, Ma Y, Liu W, Wang Y, Chi X, Shao S, Dong Y, Zhan Q, Liu X
Digestive diseases and sciences 2020 Apr;65(4):1032-1041
Digestive diseases and sciences 2020 Apr;65(4):1032-1041
RUNX3 inhibits the invasion and migration of esophageal squamous cell carcinoma by reversing the epithelial‑mesenchymal transition through TGF‑β/Smad signaling.
Xiao Z, Tian Y, Jia Y, Shen Q, Jiang W, Chen G, Shang B, Shi M, Wang Z, Zhao X
Oncology reports 2020 Apr;43(4):1289-1299
Oncology reports 2020 Apr;43(4):1289-1299
Downregulation of MiD49 contributes to tumor growth and metastasis of human pancreatic cancer.
Bai L, Liang J, Li L, Li E
Oncology reports 2020 Apr;43(4):1208-1220
Oncology reports 2020 Apr;43(4):1208-1220
METTL3/YTHDF2 m(6) A axis promotes tumorigenesis by degrading SETD7 and KLF4 mRNAs in bladder cancer.
Xie H, Li J, Ying Y, Yan H, Jin K, Ma X, He L, Xu X, Liu B, Wang X, Zheng X, Xie L
Journal of cellular and molecular medicine 2020 Apr;24(7):4092-4104
Journal of cellular and molecular medicine 2020 Apr;24(7):4092-4104
BHLHE41 suppresses MCF-7 cell invasion via MAPK/JNK pathway.
Zhang D, Zheng Q, Wang C, Zhao N, Liu Y, Wang E
Journal of cellular and molecular medicine 2020 Apr;24(7):4001-4010
Journal of cellular and molecular medicine 2020 Apr;24(7):4001-4010
Sirt6 attenuates hypoxia-induced tubular epithelial cell injury via targeting G2/M phase arrest.
Gao Z, Chen X, Fan Y, Zhu K, Shi M, Ding G
Journal of cellular physiology 2020 Apr;235(4):3463-3473
Journal of cellular physiology 2020 Apr;235(4):3463-3473
Stromal fibroblast-derived MFAP5 promotes the invasion and migration of breast cancer cells via Notch1/slug signaling.
Chen Z, Yan X, Li K, Ling Y, Kang H
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2020 Apr;22(4):522-531
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2020 Apr;22(4):522-531
Novel nortriterpenoids with new skeletons and limonoids from the fruits of Evodia rutaecarpa and their bioactivities.
Shi YS, Xia HM, Wu CH, Li CB, Duan CC, Che C, Zhang XJ, Li HT, Zhang Y, Zhang XF
Fitoterapia 2020 Apr;142:104503
Fitoterapia 2020 Apr;142:104503
Cullin-7 (CUL7) is overexpressed in glioma cells and promotes tumorigenesis via NF-κB activation.
Xu J, Zhang Z, Qian M, Wang S, Qiu W, Chen Z, Sun Z, Xiong Y, Wang C, Sun X, Zhao R, Xue H, Li G
Journal of experimental & clinical cancer research : CR 2020 Apr 6;39(1):59
Journal of experimental & clinical cancer research : CR 2020 Apr 6;39(1):59
Micro-vesicles from mesenchymal stem cells over-expressing miR-34a inhibit transforming growth factor-β1-induced epithelial-mesenchymal transition in renal tubular epithelial cells in vitro.
He J, Jiang YL, Wang Y, Tian XJ, Sun SR
Chinese medical journal 2020 Apr 5;133(7):800-807
Chinese medical journal 2020 Apr 5;133(7):800-807
The YY1/miR-548t-5p/CXCL11 signaling axis regulates cell proliferation and metastasis in human pancreatic cancer.
Ge WL, Chen Q, Meng LD, Huang XM, Shi GD, Zong QQ, Shen P, Lu YC, Zhang YH, Miao Y, Zhang JJ, Jiang KR
Cell death & disease 2020 Apr 27;11(4):294
Cell death & disease 2020 Apr 27;11(4):294
CCL5 derived from tumor-associated macrophages promotes prostate cancer stem cells and metastasis via activating β-catenin/STAT3 signaling.
Huang R, Wang S, Wang N, Zheng Y, Zhou J, Yang B, Wang X, Zhang J, Guo L, Wang S, Chen Z, Wang Z, Xiang S
Cell death & disease 2020 Apr 16;11(4):234
Cell death & disease 2020 Apr 16;11(4):234
Fermented blueberry pomace ameliorates intestinal barrier function through the NF-κB-MLCK signaling pathway in high-fat diet mice.
Cheng Y, Wu T, Tang S, Liang F, Fang Y, Cao W, Pan S, Xu X
Food & function 2020 Apr 1;11(4):3167-3179
Food & function 2020 Apr 1;11(4):3167-3179
MicroRNA-23a-3p Inhibits Mucosal Melanoma Growth and Progression through Targeting Adenylate Cyclase 1 and Attenuating cAMP and MAPK Pathways.
Ma M, Dai J, Tang H, Xu T, Yu S, Si L, Cui C, Sheng X, Chi Z, Mao L, Wu X, Yang L, Yu H, Li S, Lian B, Tang B, Wang X, Yan X, Bai X, Zhou L, Kong Y, Guo J
Theranostics 2019;9(4):945-960
Theranostics 2019;9(4):945-960
Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis.
Xie C, Zhu J, Jiang Y, Chen J, Wang X, Geng S, Wu J, Zhong C, Li X, Meng Z
Theranostics 2019;9(16):4827-4840
Theranostics 2019;9(16):4827-4840
Temporal inhibition of mouse mammary gland cancer metastasis by CORM-A1 and DETA/NO combination therapy.
Porshneva K, Papiernik D, Psurski M, Łupicka-Słowik A, Matkowski R, Ekiert M, Nowak M, Jarosz J, Banach J, Milczarek M, Goszczyński TM, Sieńczyk M, Wietrzyk J
Theranostics 2019;9(13):3918-3939
Theranostics 2019;9(13):3918-3939
SORBS2, mediated by MEF2D, suppresses the metastasis of human hepatocellular carcinoma by inhibitiing the c-Abl-ERK signaling pathway.
Yan B, Peng Z, Xing C
American journal of cancer research 2019;9(12):2706-2718
American journal of cancer research 2019;9(12):2706-2718
SERPIND1 Affects the Malignant Biological Behavior of Epithelial Ovarian Cancer via the PI3K/AKT Pathway: A Mechanistic Study.
Guo Q, Zhu L, Wang C, Wang S, Nie X, Liu J, Liu Q, Hao Y, Li X, Lin B
Frontiers in oncology 2019;9:954
Frontiers in oncology 2019;9:954
CAPE-pNO(2) Inhibited the Growth and Metastasis of Triple-Negative Breast Cancer via the EGFR/STAT3/Akt/E-Cadherin Signaling Pathway.
Huang Q, Li S, Zhang L, Qiao X, Zhang Y, Zhao X, Xiao G, Li Z
Frontiers in oncology 2019;9:461
Frontiers in oncology 2019;9:461
Identification of RE1-Silencing Transcription Factor as a Promoter of Metastasis in Pancreatic Cancer.
Jin H, Liu P, Kong L, Fei X, Gao Y, Wu T, Sun D, Tan X
Frontiers in oncology 2019;9:291
Frontiers in oncology 2019;9:291
Scorpion Venom Analgesic Peptide, BmK AGAP Inhibits Stemness, and Epithelial-Mesenchymal Transition by Down-Regulating PTX3 in Breast Cancer.
Kampo S, Ahmmed B, Zhou T, Owusu L, Anabah TW, Doudou NR, Kuugbee ED, Cui Y, Lu Z, Yan Q, Wen QP
Frontiers in oncology 2019;9:21
Frontiers in oncology 2019;9:21
LncRNA SNHG16 promotes epithelial- mesenchymal transition via down-regulation of DKK3 in gastric cancer.
Zhou C, Zhao J, Liu J, Wei S, Xia Y, Xia W, Bi Y, Yan Z, Huang H
Cancer biomarkers : section A of Disease markers 2019;26(4):393-401
Cancer biomarkers : section A of Disease markers 2019;26(4):393-401
LncRNA ZFAS1 promotes proliferation and migration and inhibits apoptosis in nasopharyngeal carcinoma via the PI3K/AKT pathway in vitro.
Wang X, Jin Q, Wang X, Chen W, Cai Z
Cancer biomarkers : section A of Disease markers 2019;26(2):171-182
Cancer biomarkers : section A of Disease markers 2019;26(2):171-182
The long noncoding RNA LINC00483 promotes lung adenocarcinoma progression by sponging miR-204-3p.
Yang S, Liu T, Sun Y, Liang X
Cellular & molecular biology letters 2019;24:70
Cellular & molecular biology letters 2019;24:70
Downregulation of CDKL1 suppresses neuroblastoma cell proliferation, migration and invasion.
Li W, Cao J, Liu J, Chu W, Zhang C, Chen S, Kang Z
Cellular & molecular biology letters 2019;24:19
Cellular & molecular biology letters 2019;24:19
Betulinic Acid Suppresses Breast Cancer Metastasis by Targeting GRP78-Mediated Glycolysis and ER Stress Apoptotic Pathway.
Zheng Y, Liu P, Wang N, Wang S, Yang B, Li M, Chen J, Situ H, Xie M, Lin Y, Wang Z
Oxidative medicine and cellular longevity 2019;2019:8781690
Oxidative medicine and cellular longevity 2019;2019:8781690
Dual-target MDM2/MDMX inhibitor increases the sensitization of doxorubicin and inhibits migration and invasion abilities of triple-negative breast cancer cells through activation of TAB1/TAK1/p38 MAPK pathway.
Fan Y, Li M, Ma K, Hu Y, Jing J, Shi Y, Li E, Dong D
Cancer biology & therapy 2019;20(5):617-632
Cancer biology & therapy 2019;20(5):617-632
2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol reverses EGF-induced cell migration and invasion through down-regulation of MDM2 in breast cancer cell lines.
Zheng D, Chang X, Liu Y, Xu J, Gou W, Li Z, Zuo D, Zhang W, Wu Y
Cancer biology & therapy 2019;20(4):513-523
Cancer biology & therapy 2019;20(4):513-523
SKA1 promotes malignant phenotype and progression of glioma via multiple signaling pathways.
Wang X, Zeng Y, Zhou M, Zhang X, Xu A, Lin J, Wu Z, Xie C, Luo J, Ding S, Zhan Z, Long H, Song Y
Cancer cell international 2019;19:324
Cancer cell international 2019;19:324
Strand-specific miR-28-3p and miR-28-5p have differential effects on nasopharyngeal cancer cells proliferation, apoptosis, migration and invasion.
Lv Y, Yang H, Ma X, Wu G
Cancer cell international 2019;19:187
Cancer cell international 2019;19:187
TGF-β1 Induces Epithelial-Mesenchymal Transition of Chronic Sinusitis with Nasal Polyps through MicroRNA-21.
Li X, Li C, Zhu G, Yuan W, Xiao ZA
International archives of allergy and immunology 2019;179(4):304-319
International archives of allergy and immunology 2019;179(4):304-319
A panel of biomarkers for skin squamous cell carcinoma: various functional entities and differential responses to resveratrol.
Sun Y, Li A, Liu X, Wang Q, Bai Y, Liu Z, Huang L, Wu M, Li H, Miao J, Liu J
International journal of clinical and experimental pathology 2019;12(4):1363-1377
International journal of clinical and experimental pathology 2019;12(4):1363-1377
CLK3 Is A Direct Target Of miR-144 And Contributes To Aggressive Progression In Hepatocellular Carcinoma.
Li H, Cui X, Hu Q, Chen X, Zhou P
OncoTargets and therapy 2019;12:9201-9213
OncoTargets and therapy 2019;12:9201-9213
Silencing of CARMA3 inhibits bladder cancer cell migration and invasion via deactivating β-catenin signaling pathway.
Man X, Liu T, Jiang Y, Zhang Z, Zhu Y, Li Z, Kong C, He J
OncoTargets and therapy 2019;12:6309-6322
OncoTargets and therapy 2019;12:6309-6322
ODC1 promotes proliferation and mobility via the AKT/GSK3β/β-catenin pathway and modulation of acidotic microenvironment in human hepatocellular carcinoma.
Ye Z, Zeng Z, Shen Y, Yang Q, Chen D, Chen Z, Shen S
OncoTargets and therapy 2019;12:4081-4092
OncoTargets and therapy 2019;12:4081-4092
Exosomal Tenascin-c induces proliferation and invasion of pancreatic cancer cells by WNT signaling.
Qian S, Tan X, Liu X, Liu P, Wu Y
OncoTargets and therapy 2019;12:3197-3205
OncoTargets and therapy 2019;12:3197-3205
High expression of long non-coding RNA NNT-AS1 facilitates progression of cholangiocarcinoma through promoting epithelial-mesenchymal transition.
Gu Y, Li C, Xiao L, Li J, Pei H, Xu D, Jiang Y, Zhang X, Zhang L, Li K, Zhu Z, Chen X
American journal of translational research 2019;11(9):5438-5456
American journal of translational research 2019;11(9):5438-5456
Long noncoding RNA CASC15 predicts unfavorable prognosis and exerts oncogenic functions in non-small cell lung cancer.
Li M, Chen Y, Zhu J, Gao Z, Wang T, Zhou P
American journal of translational research 2019;11(7):4303-4314
American journal of translational research 2019;11(7):4303-4314
EYA1 promotes cell migration and tumor metastasis in hepatocellular carcinoma.
Kong D, Ma W, Zhang D, Cui Q, Wang K, Tang J, Liu Z, Wu G
American journal of translational research 2019;11(4):2328-2338
American journal of translational research 2019;11(4):2328-2338
Blocking transforming growth factor-beta reduces the migration and invasion of the residual tumour after TAE.
Song S, He X, Zeng Z, Zhang H, Yao Q, Yang F, Zheng C, Guo X
American journal of translational research 2019;11(4):2155-2167
American journal of translational research 2019;11(4):2155-2167
Long noncoding RNA HCP5 contributes to epithelial-mesenchymal transition in colorectal cancer through ZEB1 activation and interacting with miR-139-5p.
Yang C, Sun J, Liu W, Yang Y, Chu Z, Yang T, Gui Y, Wang D
American journal of translational research 2019;11(2):953-963
American journal of translational research 2019;11(2):953-963
Lipase member H is a downstream molecular target of hypoxia inducible factor-1α and promotes papillary thyroid carcinoma cell migration in BCPAP and KTC-1 cell lines.
Li Y, Zhou X, Zhang Q, Chen E, Sun Y, Ye D, Wang O, Zhang X, Lyu J
Cancer management and research 2019;11:931-941
Cancer management and research 2019;11:931-941
TMEFF1 overexpression and its mechanism for tumor promotion in ovarian cancer.
Nie X, Liu C, Guo Q, Zheng MJ, Gao LL, Li X, Liu DW, Zhu LC, Liu JJ, Lin B
Cancer management and research 2019;11:839-855
Cancer management and research 2019;11:839-855
Overexpressed PKMYT1 promotes tumor progression and associates with poor survival in esophageal squamous cell carcinoma.
Zhang Q, Zhao X, Zhang C, Wang W, Li F, Liu D, Wu K, Zhu D, Liu S, Shen C, Yuan X, Zhang K, Yang Y, Zhang Y, Zhao S
Cancer management and research 2019;11:7813-7824
Cancer management and research 2019;11:7813-7824
Disulfiram inhibits epithelial-mesenchymal transition through TGFβ-ERK-Snail pathway independently of Smad4 to decrease oral squamous cell carcinoma metastasis.
Bu W, Wang Z, Meng L, Li X, Liu X, Chen Y, Xin Y, Li B, Sun H
Cancer management and research 2019;11:3887-3898
Cancer management and research 2019;11:3887-3898
The oncogenic role of GNL3 in the progression and metastasis of osteosarcoma.
Li T, Li L, Wu X, Tian K, Wang Y
Cancer management and research 2019;11:2179-2188
Cancer management and research 2019;11:2179-2188
Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway.
Zhang Q, Meng X, Qin G, Xue X, Dang N
Journal of Cancer 2019;10(5):1197-1208
Journal of Cancer 2019;10(5):1197-1208
RUFY3 Predicts Poor Prognosis and Promotes Metastasis through Epithelial-mesenchymal Transition in Lung Adenocarcinoma.
Men W, Li W, Li Y, Zhao J, Qu X, Li P, Gong S
Journal of Cancer 2019;10(25):6278-6285
Journal of Cancer 2019;10(25):6278-6285
Verteporfin suppresses the proliferation, epithelial-mesenchymal transition and stemness of head and neck squamous carcinoma cells via inhibiting YAP1.
Liu K, Du S, Gao P, Zheng J
Journal of Cancer 2019;10(18):4196-4207
Journal of Cancer 2019;10(18):4196-4207
Dysregulation of MiR-519d Affects Oral Squamous Cell Carcinoma Invasion and Metastasis by Targeting MMP3.
Jin Y, Li Y, Wang X, Yang Y
Journal of Cancer 2019;10(12):2720-2734
Journal of Cancer 2019;10(12):2720-2734
Small Nucleolar RNA 71A Promotes Lung Cancer Cell Proliferation, Migration and Invasion via MAPK/ERK Pathway.
Tang G, Zeng Z, Sun W, Li S, You C, Tang F, Peng S, Ma S, Luo Y, Xu J, Tian X, Zhang N, Gong Y, Xie C
Journal of Cancer 2019;10(10):2261-2275
Journal of Cancer 2019;10(10):2261-2275
MicroRNA-532-3p Suppresses Malignant Behaviors of Tongue Squamous Cell Carcinoma via Regulating CCR7.
Feng C, So HI, Yin S, Su X, Xu Q, Wang S, Duan W, Zhang E, Sun C, Xu Z
Frontiers in pharmacology 2019;10:940
Frontiers in pharmacology 2019;10:940
Activation of CXCL6/CXCR1/2 Axis Promotes the Growth and Metastasis of Osteosarcoma Cells in vitro and in vivo.
Liu G, An L, Zhang H, Du P, Sheng Y
Frontiers in pharmacology 2019;10:307
Frontiers in pharmacology 2019;10:307
Biomimetic Human Tissue Model for Long-Term Study of Neisseria gonorrhoeae Infection.
Heydarian M, Yang T, Schweinlin M, Steinke M, Walles H, Rudel T, Kozjak-Pavlovic V
Frontiers in microbiology 2019;10:1740
Frontiers in microbiology 2019;10:1740
Knockdown of SP1/Syncytin1 axis inhibits the proliferation and metastasis through the AKT and ERK1/2 signaling pathways in non-small cell lung cancer.
Li X, Fu Y, Xia X, Zhang X, Xiao K, Zhuang X, Zhang Y
Cancer medicine 2019 Sep;8(12):5750-5759
Cancer medicine 2019 Sep;8(12):5750-5759
Nonconserved miR-608 suppresses prostate cancer progression through RAC2/PAK4/LIMK1 and BCL2L1/caspase-3 pathways by targeting the 3'-UTRs of RAC2/BCL2L1 and the coding region of PAK4.
Zhang X, Fang J, Chen S, Wang W, Meng S, Liu B
Cancer medicine 2019 Sep;8(12):5716-5734
Cancer medicine 2019 Sep;8(12):5716-5734
Overexpression of matrix metalloproteinase-9 in breast cancer cell lines remarkably increases the cell malignancy largely via activation of transforming growth factor beta/SMAD signalling.
Dong H, Diao H, Zhao Y, Xu H, Pei S, Gao J, Wang J, Hussain T, Zhao D, Zhou X, Lin D
Cell proliferation 2019 Sep;52(5):e12633
Cell proliferation 2019 Sep;52(5):e12633
Transforming growth factor β1 promotes fibroblast-like synoviocytes migration and invasion via TGF-β1/Smad signaling in rheumatoid arthritis.
Zhu D, Zhao J, Lou A, Huang Q, OuYang Q, Zhu J, Fan M, He Y, Ren H, Yang M
Molecular and cellular biochemistry 2019 Sep;459(1-2):141-150
Molecular and cellular biochemistry 2019 Sep;459(1-2):141-150
Fluorene-9-bisphenol inhibits epithelial-mesenchymal transition of human endometrial cancer Ishikawa cells by repressing TGF-β signaling pathway.
Wang L, Zhuang T, Li F, Wei W
Environmental science and pollution research international 2019 Sep;26(26):27407-27413
Environmental science and pollution research international 2019 Sep;26(26):27407-27413
Thioredoxin-interacting protein deficiency alleviates phenotypic alterations of podocytes via inhibition of mTOR activation in diabetic nephropathy.
Song S, Qiu D, Shi Y, Wang S, Zhou X, Chen N, Wei J, Wu M, Wu H, Duan H
Journal of cellular physiology 2019 Sep;234(9):16485-16502
Journal of cellular physiology 2019 Sep;234(9):16485-16502
Astaxanthin protects against renal fibrosis through inhibiting myofibroblast activation and promoting CD8(+) T cell recruitment.
Diao W, Chen W, Cao W, Yuan H, Ji H, Wang T, Chen W, Zhu X, Zhou H, Guo H, Zhao X
Biochimica et biophysica acta. General subjects 2019 Sep;1863(9):1360-1370
Biochimica et biophysica acta. General subjects 2019 Sep;1863(9):1360-1370
Downregulated lncRNA UCA1 acts as ceRNA to adsorb microRNA-498 to repress proliferation, invasion and epithelial mesenchymal transition of esophageal cancer cells by decreasing ZEB2 expression.
Wang P, Liu X, Han G, Dai S, Ni Q, Xiao S, Huang J
Cell cycle (Georgetown, Tex.) 2019 Sep;18(18):2359-2376
Cell cycle (Georgetown, Tex.) 2019 Sep;18(18):2359-2376
MicroRNA-330-3p promotes brain metastasis and epithelial-mesenchymal transition via GRIA3 in non-small cell lung cancer.
Wei C, Zhang R, Cai Q, Gao X, Tong F, Dong J, Hu Y, Wu G, Dong X
Aging 2019 Sep 8;11(17):6734-6761
Aging 2019 Sep 8;11(17):6734-6761
Long non-coding RNA linc00645 promotes TGF-β-induced epithelial-mesenchymal transition by regulating miR-205-3p-ZEB1 axis in glioma.
Li C, Zheng H, Hou W, Bao H, Xiong J, Che W, Gu Y, Sun H, Liang P
Cell death & disease 2019 Sep 26;10(10):717
Cell death & disease 2019 Sep 26;10(10):717
KIF18A promotes head and neck squamous cell carcinoma invasion and migration via activation of Akt signaling pathway.
Liu G, Cai G, He X, Huang D, Zhu G, Chen C, Zhang X
Translational cancer research 2019 Oct;8(6):2252-2263
Translational cancer research 2019 Oct;8(6):2252-2263
Sulforaphane inhibits epithelial-mesenchymal transition by activating extracellular signal-regulated kinase 5 in lung cancer cells.
Chen Y, Chen JQ, Ge MM, Zhang Q, Wang XQ, Zhu JY, Xie CF, Li XT, Zhong CY, Han HY
The Journal of nutritional biochemistry 2019 Oct;72:108219
The Journal of nutritional biochemistry 2019 Oct;72:108219
Macrophage migration inhibitory factor promotes the invasion and metastasis of oral squamous cell carcinoma through matrix metalloprotein-2/9.
Wang SS, Zheng M, Pang X, Zhang M, Yu XH, Wu JB, Gao XL, Wu JS, Yang X, Tang YJ, Tang YL, Liang XH
Molecular carcinogenesis 2019 Oct;58(10):1809-1821
Molecular carcinogenesis 2019 Oct;58(10):1809-1821
AEBP1, a prognostic indicator, promotes colon adenocarcinoma cell growth and metastasis through the NF-κB pathway.
Xing Y, Zhang Z, Chi F, Zhou Y, Ren S, Zhao Z, Zhu Y, Piao D
Molecular carcinogenesis 2019 Oct;58(10):1795-1808
Molecular carcinogenesis 2019 Oct;58(10):1795-1808
Downregulation of nicotinamide N-methyltransferase inhibits migration and epithelial-mesenchymal transition of esophageal squamous cell carcinoma via Wnt/β-catenin pathway.
Cui Y, Zhang L, Wang W, Ma S, Liu H, Zang X, Zhang Y, Guan F
Molecular and cellular biochemistry 2019 Oct;460(1-2):93-103
Molecular and cellular biochemistry 2019 Oct;460(1-2):93-103
A novel tetravalent bispecific antibody targeting programmed death 1 and tyrosine-protein kinase Met for treatment of gastric cancer.
Hou W, Yuan Q, Yuan X, Wang Y, Mo W, Wang H, Yu M
Investigational new drugs 2019 Oct;37(5):876-889
Investigational new drugs 2019 Oct;37(5):876-889
Wnt7a, frequently silenced by CpG methylation, inhibits tumor growth and metastasis via suppressing epithelial-mesenchymal transition in gastric cancer.
Liu Y, Qiao Y, Zhang H, Li W, Zheng J
Journal of cellular biochemistry 2019 Oct;120(10):18142-18151
Journal of cellular biochemistry 2019 Oct;120(10):18142-18151
Chronic CagA-positive Helicobacter pylori infection with MNNG stimulation synergistically induces mesenchymal and cancer stem cell-like properties in gastric mucosal epithelial cells.
Lin L, Wei H, Yi J, Xie B, Chen J, Zhou C, Wang L, Yang Y
Journal of cellular biochemistry 2019 Oct;120(10):17635-17649
Journal of cellular biochemistry 2019 Oct;120(10):17635-17649
Inhibition of high mobility group box 1 (HMGB1) attenuates podocyte apoptosis and epithelial-mesenchymal transition by regulating autophagy flux.
Jin J, Gong J, Zhao L, Zhang H, He Q, Jiang X
Journal of diabetes 2019 Oct;11(10):826-836
Journal of diabetes 2019 Oct;11(10):826-836
CircWHSC1 promotes ovarian cancer progression by regulating MUC1 and hTERT through sponging miR-145 and miR-1182.
Zong ZH, Du YP, Guan X, Chen S, Zhao Y
Journal of experimental & clinical cancer research : CR 2019 Oct 30;38(1):437
Journal of experimental & clinical cancer research : CR 2019 Oct 30;38(1):437
CD36 promotes the epithelial-mesenchymal transition and metastasis in cervical cancer by interacting with TGF-β.
Deng M, Cai X, Long L, Xie L, Ma H, Zhou Y, Liu S, Zeng C
Journal of translational medicine 2019 Oct 26;17(1):352
Journal of translational medicine 2019 Oct 26;17(1):352
Discovery of Novel Aryl Carboxamide Derivatives as Hypoxia-Inducible Factor 1α Signaling Inhibitors with Potent Activities of Anticancer Metastasis.
Liu M, Liang Y, Zhu Z, Wang J, Cheng X, Cheng J, Xu B, Li R, Liu X, Wang Y
Journal of medicinal chemistry 2019 Oct 24;62(20):9299-9314
Journal of medicinal chemistry 2019 Oct 24;62(20):9299-9314
Functional genetic variants of RUVBL1 predict overall survival of Chinese patients with epithelial ovarian cancer.
Li H, Tong X, Xu Y, Wang M, Dai H, Shi T, Sun M, Chen K, Cheng X, Wei Q
Carcinogenesis 2019 Oct 16;40(10):1209-1219
Carcinogenesis 2019 Oct 16;40(10):1209-1219
Influence of Wilms' tumor suppressor gene WT1 on bovine Sertoli cells polarity and tight junctions via non-canonical WNT signaling pathway.
Wang X, Adegoke EO, Ma M, Huang F, Zhang H, Adeniran SO, Zheng P, Zhang G
Theriogenology 2019 Oct 15;138:84-93
Theriogenology 2019 Oct 15;138:84-93
Tumor-suppressive activity of Hnf1β in Wilms' tumor.
Liu Y, Kanyomse Q, Xie Y
Bioscience, biotechnology, and biochemistry 2019 Nov;83(11):2008-2015
Bioscience, biotechnology, and biochemistry 2019 Nov;83(11):2008-2015
Curcumin mitigates the epithelial-to-mesenchymal transition in biliary epithelial cells through upregulating CD109 expression.
Fan J, Wang Q, Zhang Z, Sun L
Drug development research 2019 Nov;80(7):992-999
Drug development research 2019 Nov;80(7):992-999
O‑GlcNAc modification influences endometrial receptivity by promoting endometrial cell proliferation, migration and invasion.
Han X, Li X, Liu H, Zhang H, Li A, Dong M, Xu Y, Yan B, Sui L, Kong Y
Oncology reports 2019 Nov;42(5):2065-2074
Oncology reports 2019 Nov;42(5):2065-2074
Dehydrogenase/reductase SDR family member 2 silencing sensitizes an oxaliplatin‑resistant cell line to oxaliplatin by inhibiting excision repair cross‑complementing group 1 protein expression.
Li JM, Jiang GM, Zhao L, Yang F, Yuan WQ, Wang H, Luo YQ
Oncology reports 2019 Nov;42(5):1725-1734
Oncology reports 2019 Nov;42(5):1725-1734
Niban protein regulates apoptosis in HK-2 cells via caspase-dependent pathway.
Tang S, Wang J, Liu J, Huang Y, Zhou Y, Yang S, Zhang W, Yang M, Zhang H
Renal failure 2019 Nov;41(1):455-466
Renal failure 2019 Nov;41(1):455-466
The protective effect of lithocholic acid on the intestinal epithelial barrier is mediated by the vitamin D receptor via a SIRT1/Nrf2 and NF-κB dependent mechanism in Caco-2 cells.
Yao B, He J, Yin X, Shi Y, Wan J, Tian Z
Toxicology letters 2019 Nov;316:109-118
Toxicology letters 2019 Nov;316:109-118
Long-term exposure of 4-hydroxyestradiol induces the cancer cell characteristics via upregulating CYP1B1 in MCF-10A cells.
Lanxiang W, Bin W, Ge X, Yutang H, Chunjie W, Honghao Z
Toxicology mechanisms and methods 2019 Nov;29(9):686-692
Toxicology mechanisms and methods 2019 Nov;29(9):686-692
miR-611 promotes the proliferation, migration and invasion of tongue squamous cell carcinoma cells by targeting FOXN3.
Chen S, Zhang J, Sun L, Li X, Bai J, Zhang H, Li T
Oral diseases 2019 Nov;25(8):1906-1918
Oral diseases 2019 Nov;25(8):1906-1918
The miR-27a-3p/USP25 axis participates in the pathogenesis of recurrent miscarriage by inhibiting trophoblast migration and invasion.
Ding J, Cheng Y, Zhang Y, Liao S, Yin T, Yang J
Journal of cellular physiology 2019 Nov;234(11):19951-19963
Journal of cellular physiology 2019 Nov;234(11):19951-19963
Sirtuin6 (SIRT6) Promotes the EMT of Hepatocellular Carcinoma by Stimulating Autophagic Degradation of E-Cadherin.
Han LL, Jia L, Wu F, Huang C
Molecular cancer research : MCR 2019 Nov;17(11):2267-2280
Molecular cancer research : MCR 2019 Nov;17(11):2267-2280
Downregulation of Rab23 inhibits proliferation, invasion, and metastasis of human ovarian cancer.
Gao L, Zheng M, Guo Q, Nie X, Li X, Hao Y, Liu J, Zhu L, Lin B
The international journal of biochemistry & cell biology 2019 Nov;116:105617
The international journal of biochemistry & cell biology 2019 Nov;116:105617
G9a and histone deacetylases are crucial for Snail2-mediated E-cadherin repression and metastasis in hepatocellular carcinoma.
Hu Y, Zheng Y, Dai M, Wang X, Wu J, Yu B, Zhang H, Cui Y, Kong W, Wu H, Yu X
Cancer science 2019 Nov;110(11):3442-3452
Cancer science 2019 Nov;110(11):3442-3452
PITPNA-AS1 abrogates the inhibition of miR-876-5p on WNT5A to facilitate hepatocellular carcinoma progression.
Sun J, Zhang Y, Li B, Dong Y, Sun C, Zhang F, Jin L, Chen D, Wang W
Cell death & disease 2019 Nov 7;10(11):844
Cell death & disease 2019 Nov 7;10(11):844
Inhibiting Hypoxia and Chemotherapy-Induced Cancer Cell Metastasis under a Valid Therapeutic Effect by an Assistance of Biomimetic Oxygen Delivery.
Jiang MS, Yin XY, Qin B, Xuan SY, Yuan XL, Yin H, Zhu C, Li X, Yang J, Du YZ, Luo LH, You J
Molecular pharmaceutics 2019 Nov 4;16(11):4530-4541
Molecular pharmaceutics 2019 Nov 4;16(11):4530-4541
Targetting an LncRNA P5848-ENO1 axis inhibits tumor growth in hepatocellular carcinoma.
Zhu X, Yu H, Li B, Quan J, Zeng Z, Li G, Liu J
Bioscience reports 2019 Nov 29;39(11)
Bioscience reports 2019 Nov 29;39(11)
Rhomboid-Like-2 Intramembrane Protease Mediates Metalloprotease-Independent Regulation of Cadherins.
Battistini C, Rehman M, Avolio M, Arduin A, Valdembri D, Serini G, Tamagnone L
International journal of molecular sciences 2019 Nov 27;20(23)
International journal of molecular sciences 2019 Nov 27;20(23)
Sinulariolide Inhibits Gastric Cancer Cell Migration and Invasion through Downregulation of the EMT Process and Suppression of FAK/PI3K/AKT/mTOR and MAPKs Signaling Pathways.
Wu YJ, Lin SH, Din ZH, Su JH, Liu CI
Marine drugs 2019 Nov 27;17(12)
Marine drugs 2019 Nov 27;17(12)
β2AR-HIF-1α-CXCL12 signaling of osteoblasts activated by isoproterenol promotes migration and invasion of prostate cancer cells.
Huang Z, Li G, Zhang Z, Gu R, Wang W, Lai X, Cui ZK, Zeng F, Xu S, Deng F
BMC cancer 2019 Nov 26;19(1):1142
BMC cancer 2019 Nov 26;19(1):1142
DEK Is a Potential Biomarker Associated with Malignant Phenotype in Gastric Cancer Tissues and Plasma.
Lee KF, Tsai MM, Tsai CY, Huang CG, Ou YH, Hsieh CC, Hsieh HL, Wang CS, Lin KH
International journal of molecular sciences 2019 Nov 13;20(22)
International journal of molecular sciences 2019 Nov 13;20(22)
Amphiregulin promotes trophoblast invasion and increases MMP9/TIMP1 ratio through ERK1/2 and Akt signal pathways.
Yu Y, Fang L, Wang S, Li Y, Guo Y, Sun YP
Life sciences 2019 Nov 1;236:116899
Life sciences 2019 Nov 1;236:116899
Zinc promotes prostate cancer cell chemosensitivity to paclitaxel by inhibiting epithelial-mesenchymal transition and inducing apoptosis.
Xue YN, Yu BB, Liu YN, Guo R, Li JL, Zhang LC, Su J, Sun LK, Li Y
The Prostate 2019 May;79(6):647-656
The Prostate 2019 May;79(6):647-656
Hypoxia promotes vasculogenic mimicry formation by vascular endothelial growth factor A mediating epithelial-mesenchymal transition in salivary adenoid cystic carcinoma.
Wang HF, Wang SS, Zheng M, Dai LL, Wang K, Gao XL, Cao MX, Yu XH, Pang X, Zhang M, Wu JB, Wu JS, Yang X, Tang YJ, Chen Y, Tang YL, Liang XH
Cell proliferation 2019 May;52(3):e12600
Cell proliferation 2019 May;52(3):e12600
RPS7 promotes cell migration through targeting epithelial-mesenchymal transition in prostate cancer.
Wen Y, An Z, Qiao B, Zhang C, Zhang Z
Urologic oncology 2019 May;37(5):297.e1-297.e7
Urologic oncology 2019 May;37(5):297.e1-297.e7
SREBP1, targeted by miR-18a-5p, modulates epithelial-mesenchymal transition in breast cancer via forming a co-repressor complex with Snail and HDAC1/2.
Zhang N, Zhang H, Liu Y, Su P, Zhang J, Wang X, Sun M, Chen B, Zhao W, Wang L, Wang H, Moran MS, Haffty BG, Yang Q
Cell death and differentiation 2019 May;26(5):843-859
Cell death and differentiation 2019 May;26(5):843-859
Upregulation of lncRNA DGCR5 correlates with better prognosis and inhibits bladder cancer progression via transcriptionally facilitating P21 expression.
Fang C, He W, Xu T, Dai J, Xu L, Sun F
Journal of cellular physiology 2019 May;234(5):6254-6262
Journal of cellular physiology 2019 May;234(5):6254-6262
SSRP1 promotes colorectal cancer progression and is negatively regulated by miR-28-5p.
Wu W, He K, Guo Q, Chen J, Zhang M, Huang K, Yang D, Wu L, Deng Y, Luo X, Yu H, Ding Q, Xiang G
Journal of cellular and molecular medicine 2019 May;23(5):3118-3129
Journal of cellular and molecular medicine 2019 May;23(5):3118-3129
Expansion and maintenance of primary corneal epithelial stem/progenitor cells by inhibition of TGFβ receptor I-mediated signaling.
Hu L, Pu Q, Zhang Y, Ma Q, Li G, Li X
Experimental eye research 2019 May;182:44-56
Experimental eye research 2019 May;182:44-56
Upregulated forkhead-box A3 elevates the expression of forkhead-box A1 and forkhead-box A2 to promote metastasis in esophageal cancer.
Chen B, Yu J, Lu L, Dong F, Zhou F, Tao X, Sun E
Oncology letters 2019 May;17(5):4351-4360
Oncology letters 2019 May;17(5):4351-4360
MicroRNA-34a Promotes Renal Fibrosis by Downregulation of Klotho in Tubular Epithelial Cells.
Liu Y, Bi X, Xiong J, Han W, Xiao T, Xu X, Yang K, Liu C, Jiang W, He T, Yu Y, Li Y, Zhang J, Zhang B, Zhao J
Molecular therapy : the journal of the American Society of Gene Therapy 2019 May 8;27(5):1051-1065
Molecular therapy : the journal of the American Society of Gene Therapy 2019 May 8;27(5):1051-1065
miR-340-FHL2 axis inhibits cell growth and metastasis in ovarian cancer.
Huang Z, Li Q, Luo K, Zhang Q, Geng J, Zhou X, Xu Y, Qian M, Zhang JA, Ji L, Wu J
Cell death & disease 2019 May 8;10(5):372
Cell death & disease 2019 May 8;10(5):372
Transcriptional control of subtype switching ensures adaptation and growth of pancreatic cancer.
Adams CR, Htwe HH, Marsh T, Wang AL, Montoya ML, Subbaraj L, Tward AD, Bardeesy N, Perera RM
eLife 2019 May 28;8
eLife 2019 May 28;8
The HBx-CTTN interaction promotes cell proliferation and migration of hepatocellular carcinoma via CREB1.
Li Y, Fu Y, Hu X, Sun L, Tang D, Li N, Peng F, Fan XG
Cell death & disease 2019 May 28;10(6):405
Cell death & disease 2019 May 28;10(6):405
M2 macrophages promote NSCLC metastasis by upregulating CRYAB.
Guo Z, Song J, Hao J, Zhao H, Du X, Li E, Kuang Y, Yang F, Wang W, Deng J, Wang Q
Cell death & disease 2019 May 16;10(6):377
Cell death & disease 2019 May 16;10(6):377
Triptolide prevents proliferation and migration of Esophageal Squamous Cell Cancer via MAPK/ERK signaling pathway.
Yanchun M, Yi W, Lu W, Yu Q, Jian Y, Pengzhou K, Ting Y, Hongyi L, Fang W, Xiaolong C, Yongping C
European journal of pharmacology 2019 May 15;851:43-51
European journal of pharmacology 2019 May 15;851:43-51
CXCL12/CXCR4 pathway orchestrates CSC-like properties by CAF recruited tumor associated macrophage in OSCC.
Li X, Bu W, Meng L, Liu X, Wang S, Jiang L, Ren M, Fan Y, Sun H
Experimental cell research 2019 May 15;378(2):131-138
Experimental cell research 2019 May 15;378(2):131-138
miR-130a-3p regulated TGF-β1-induced epithelial-mesenchymal transition depends on SMAD4 in EC-1 cells.
Tian X, Fei Q, Du M, Zhu H, Ye J, Qian L, Lu Z, Zhang W, Wang Y, Peng F, Chen J, Liu B, Li Q, He X, Yin L
Cancer medicine 2019 Mar;8(3):1197-1208
Cancer medicine 2019 Mar;8(3):1197-1208
lncRNA H19 promotes viability and epithelial-mesenchymal transition of lung adenocarcinoma cells by targeting miR-29b-3p and modifying STAT3.
Liu L, Liu L, Lu S
International journal of oncology 2019 Mar;54(3):929-941
International journal of oncology 2019 Mar;54(3):929-941
Stanniocalcin‑1 promotes cell proliferation, chemoresistance and metastasis in hypoxic gastric cancer cells via Bcl‑2.
Wang Y, Qi Z, Zhou M, Yang W, Hu R, Li G, Ma X, Zhang Z
Oncology reports 2019 Mar;41(3):1998-2008
Oncology reports 2019 Mar;41(3):1998-2008
PTEN downregulates WD repeat‑containing protein 66 in salivary adenoid cystic carcinoma.
Cao Y, Liu H, Xia SL, Zhang X, Bai H, Yang Q, Li J, Gao L, Jin F, Wei MJ, Lu SL, Xiao J
Oncology reports 2019 Mar;41(3):1827-1836
Oncology reports 2019 Mar;41(3):1827-1836
Wnt7a predicts poor prognosis, and contributes to growth and metastasis in tongue squamous cell carcinoma.
Jia B, Qiu X, Chu H, Sun X, Xu S, Zhao X, Zhao J
Oncology reports 2019 Mar;41(3):1749-1758
Oncology reports 2019 Mar;41(3):1749-1758
Tn antigen promotes human colorectal cancer metastasis via H-Ras mediated epithelial-mesenchymal transition activation.
Liu Z, Liu J, Dong X, Hu X, Jiang Y, Li L, Du T, Yang L, Wen T, An G, Feng G
Journal of cellular and molecular medicine 2019 Mar;23(3):2083-2092
Journal of cellular and molecular medicine 2019 Mar;23(3):2083-2092
Epithelial‑mesenchymal transition induced by bone morphogenetic protein 9 hinders cisplatin efficacy in ovarian cancer cells.
Wang Y, Yang B, Zhao J, Yu X, Liu X, Zhang L, Zhang Y, Li X, Zhai Z
Molecular medicine reports 2019 Mar;19(3):1501-1508
Molecular medicine reports 2019 Mar;19(3):1501-1508
LncRNA MIR22HG inhibits growth, migration and invasion through regulating the miR-10a-5p/NCOR2 axis in hepatocellular carcinoma cells.
Wu Y, Zhou Y, Huan L, Xu L, Shen M, Huang S, Liang L
Cancer science 2019 Mar;110(3):973-984
Cancer science 2019 Mar;110(3):973-984
Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway.
Li Z, Chen Y, An T, Liu P, Zhu J, Yang H, Zhang W, Dong T, Jiang J, Zhang Y, Jiang M, Yang X
Journal of experimental & clinical cancer research : CR 2019 Mar 29;38(1):139
Journal of experimental & clinical cancer research : CR 2019 Mar 29;38(1):139
Cysteine Dioxygenase Regulates the Epithelial Morphogenesis of Mammary Gland via Cysteine Sulfinic Acid.
Zhao J, Han Y, Ma X, Zhou Y, Yuan S, Shen Q, Ye G, Liu H, Fu P, Zhang G, Qiao B, Liu A
iScience 2019 Mar 29;13:173-189
iScience 2019 Mar 29;13:173-189
CUL4B promotes prostate cancer progression by forming positive feedback loop with SOX4.
Qi M, Hu J, Cui Y, Jiao M, Feng T, Li X, Pang Y, Chen X, Qin R, Su P, Zhang H, Wang Y, Gong Y, Han B
Oncogenesis 2019 Mar 14;8(3):23
Oncogenesis 2019 Mar 14;8(3):23
AKR1B10 (Aldo-keto reductase family 1 B10) promotes brain metastasis of lung cancer cells in a multi-organ microfluidic chip model.
Liu W, Song J, Du X, Zhou Y, Li Y, Li R, Lyu L, He Y, Hao J, Ben J, Wang W, Shi H, Wang Q
Acta biomaterialia 2019 Jun;91:195-208
Acta biomaterialia 2019 Jun;91:195-208
Protective effect of rosiglitazone on chronic renal allograft dysfunction in rats.
Deng J, Xia Y, Zhou Q, Wang X, Xiong C, Shao X, Shao M, Zou H
Transplant immunology 2019 Jun;54:20-28
Transplant immunology 2019 Jun;54:20-28
Bronchial epithelial cell extracellular vesicles ameliorate epithelial-mesenchymal transition in COPD pathogenesis by alleviating M2 macrophage polarization.
He S, Chen D, Hu M, Zhang L, Liu C, Traini D, Grau GE, Zeng Z, Lu J, Zhou G, Xie L, Sun S
Nanomedicine : nanotechnology, biology, and medicine 2019 Jun;18:259-271
Nanomedicine : nanotechnology, biology, and medicine 2019 Jun;18:259-271
Expression of miR-181a and TGF-β2 in lens epithelial cells of patients with cataractous retinal detachment and its clinical significance.
Jiang Y, Gong Y, Lin N, Qiu W
Experimental and therapeutic medicine 2019 Jun;17(6):4435-4440
Experimental and therapeutic medicine 2019 Jun;17(6):4435-4440
Platelets promote invasion and induce epithelial to mesenchymal transition in ovarian cancer cells by TGF-β signaling pathway.
Guo Y, Cui W, Pei Y, Xu D
Gynecologic oncology 2019 Jun;153(3):639-650
Gynecologic oncology 2019 Jun;153(3):639-650
circ-CSPP1 promotes proliferation, invasion and migration of ovarian cancer cells by acting as a miR-1236-3p sponge.
Li QH, Liu Y, Chen S, Zong ZH, Du YP, Sheng XJ, Zhao Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jun;114:108832
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jun;114:108832
CBLL1 is highly expressed in non-small cell lung cancer and promotes cell proliferation and invasion.
Hui L, Zhang S, Wudu M, Ren H, Xu Y, Zhang Q, Qiu X
Thoracic cancer 2019 Jun;10(6):1479-1488
Thoracic cancer 2019 Jun;10(6):1479-1488
Calcium-Activated Chloride Channel A4 (CLCA4) Plays Inhibitory Roles in Invasion and Migration Through Suppressing Epithelial-Mesenchymal Transition via PI3K/AKT Signaling in Colorectal Cancer.
Chen H, Liu Y, Jiang CJ, Chen YM, Li H, Liu QA
Medical science monitor : international medical journal of experimental and clinical research 2019 Jun 5;25:4176-4185
Medical science monitor : international medical journal of experimental and clinical research 2019 Jun 5;25:4176-4185
TRIP4 promotes tumor growth and metastasis and regulates radiosensitivity of cervical cancer by activating MAPK, PI3K/AKT, and hTERT signaling.
Che Y, Li Y, Zheng F, Zou K, Li Z, Chen M, Hu S, Tian C, Yu W, Guo W, Luo M, Deng W, Zou L
Cancer letters 2019 Jun 28;452:1-13
Cancer letters 2019 Jun 28;452:1-13
Acetylation of PHF5A Modulates Stress Responses and Colorectal Carcinogenesis through Alternative Splicing-Mediated Upregulation of KDM3A.
Wang Z, Yang X, Liu C, Li X, Zhang B, Wang B, Zhang Y, Song C, Zhang T, Liu M, Liu B, Ren M, Jiang H, Zou J, Liu X, Zhang H, Zhu WG, Yin Y, Zhang Z, Gu W, Luo J
Molecular cell 2019 Jun 20;74(6):1250-1263.e6
Molecular cell 2019 Jun 20;74(6):1250-1263.e6
NAV2 facilitates invasion of cutaneous melanoma cells by targeting SNAI2 through the GSK-3β/β-catenin pathway.
Hu W, Li X, Cheng R, Ke J, Liu Y, Ma M, Cao Y, Liu D
Archives of dermatological research 2019 Jul;311(5):399-410
Archives of dermatological research 2019 Jul;311(5):399-410
Exogenous regucalcin negatively regulates the progression of cervical adenocarcinoma.
Li X, Huang Y, Guo S, Xie M, Bin X, Shi M, Chen A, Chen S, Wu F, Hu Q, Zhou S
Oncology letters 2019 Jul;18(1):609-616
Oncology letters 2019 Jul;18(1):609-616
PKM2-regulated STAT3 promotes esophageal squamous cell carcinoma progression via TGF-β1-induced EMT.
Ma R, Liu Q, Zheng S, Liu T, Tan D, Lu X
Journal of cellular biochemistry 2019 Jul;120(7):11539-11550
Journal of cellular biochemistry 2019 Jul;120(7):11539-11550
Melatonin prevents lung injury by regulating apelin 13 to improve mitochondrial dysfunction.
Zhang L, Li F, Su X, Li Y, Wang Y, Fang R, Guo Y, Jin T, Shan H, Zhao X, Yang R, Shan H, Liang H
Experimental & molecular medicine 2019 Jul 4;51(7):1-12
Experimental & molecular medicine 2019 Jul 4;51(7):1-12
MicroRNA-23a promotes colorectal cancer cell migration and proliferation by targeting at MARK1.
Tang X, Yang M, Wang Z, Wu X, Wang D
Acta biochimica et biophysica Sinica 2019 Jul 10;51(7):661-668
Acta biochimica et biophysica Sinica 2019 Jul 10;51(7):661-668
METTL7B promotes migration and invasion in thyroid cancer through epithelial-mesenchymal transition.
Ye D, Jiang Y, Sun Y, Li Y, Cai Y, Wang Q, Wang O, Chen E, Zhang X
Journal of molecular endocrinology 2019 Jul 1;63(1):51-61
Journal of molecular endocrinology 2019 Jul 1;63(1):51-61
Dual regulatory role of CCNA2 in modulating CDK6 and MET-mediated cell-cycle pathway and EMT progression is blocked by miR-381-3p in bladder cancer.
Li J, Ying Y, Xie H, Jin K, Yan H, Wang S, Xu M, Xu X, Wang X, Yang K, Zheng X, Xie L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jan;33(1):1374-1388
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Jan;33(1):1374-1388
Chromium(VI) promotes cell migration through targeting epithelial-mesenchymal transition in prostate cancer.
Zhang C, Cai K, Feng Q, Xu Y, Zhang Z
Toxicology letters 2019 Jan;300:10-17
Toxicology letters 2019 Jan;300:10-17
FOXC1 silencing inhibits the epithelial‑to‑mesenchymal transition of glioma cells: Involvement of β‑catenin signaling.
Cao Q, Wang X, Shi Y, Zhang M, Yang J, Dong M, Mi Y, Zhang Z, Liu K, Jiang L, Wang N, Wang P
Molecular medicine reports 2019 Jan;19(1):251-261
Molecular medicine reports 2019 Jan;19(1):251-261
Everolimus Reverses Palbociclib Resistance in ER+ Human Breast Cancer Cells by Inhibiting Phosphatidylinositol 3-Kinase(PI3K)/Akt/Mammalian Target of Rapamycin (mTOR) Pathway.
Chen L, Yang G, Dong H
Medical science monitor : international medical journal of experimental and clinical research 2019 Jan 3;25:77-86
Medical science monitor : international medical journal of experimental and clinical research 2019 Jan 3;25:77-86
Tobacco smoke induced hepatic cancer stem cell-like properties through IL-33/p38 pathway.
Xie C, Zhu J, Wang X, Chen J, Geng S, Wu J, Zhong C, Li X
Journal of experimental & clinical cancer research : CR 2019 Jan 28;38(1):39
Journal of experimental & clinical cancer research : CR 2019 Jan 28;38(1):39
DHA-phospholipids (DHA-PL) and EPA-phospholipids (EPA-PL) prevent intestinal dysfunction induced by chronic stress.
Cao W, Wang C, Chin Y, Chen X, Gao Y, Yuan S, Xue C, Wang Y, Tang Q
Food & function 2019 Jan 22;10(1):277-288
Food & function 2019 Jan 22;10(1):277-288
Inhibition of ATP citrate lyase (ACLY) protects airway epithelia from PM(2.5)-induced epithelial-mesenchymal transition.
Fu Y, Lu R, Cui J, Sun H, Yang H, Meng Q, Wu S, Aschner M, Li X, Chen R
Ecotoxicology and environmental safety 2019 Jan 15;167:309-316
Ecotoxicology and environmental safety 2019 Jan 15;167:309-316
ARHGEF10L contributes to liver tumorigenesis through RhoA-ROCK1 signaling and the epithelial-mesenchymal transition.
Tang J, Liu C, Xu B, Wang D, Ma Z, Chang X
Experimental cell research 2019 Jan 1;374(1):46-68
Experimental cell research 2019 Jan 1;374(1):46-68
Native nanodiscs from blood inhibit pulmonary fibrosis.
Sun A, Lai Z, Zhao M, Mu L, Hu X
Biomaterials 2019 Feb;192:51-61
Biomaterials 2019 Feb;192:51-61
Sphingomyelin synthase 1 regulates the epithelial‑to‑mesenchymal transition mediated by the TGF‑β/Smad pathway in MDA‑MB‑231 cells.
Liu S, Hou H, Zhang P, Wu Y, He X, Li H, Yan N
Molecular medicine reports 2019 Feb;19(2):1159-1167
Molecular medicine reports 2019 Feb;19(2):1159-1167
Melatonin synergizes BRAF-targeting agent vemurafenib in melanoma treatment by inhibiting iNOS/hTERT signaling and cancer-stem cell traits.
Hao J, Fan W, Li Y, Tang R, Tian C, Yang Q, Zhu T, Diao C, Hu S, Chen M, Guo P, Long Q, Zhang C, Qin G, Yu W, Chen M, Li L, Qin L, Wang J, Zhang X, Ren Y, Zhou P, Zou L, Jiang K, Guo W, Deng W
Journal of experimental & clinical cancer research : CR 2019 Feb 4;38(1):48
Journal of experimental & clinical cancer research : CR 2019 Feb 4;38(1):48
LincK contributes to breast tumorigenesis by promoting proliferation and epithelial-to-mesenchymal transition.
Li J, Hao Y, Mao W, Xue X, Xu P, Liu L, Yuan J, Zhang D, Li N, Chen H, Zhao L, Sun Z, Luo J, Chen R, Zhao RC
Journal of hematology & oncology 2019 Feb 22;12(1):19
Journal of hematology & oncology 2019 Feb 22;12(1):19
Zoledronic acid inhibits the growth of cancer stem cell derived from cervical cancer cell by attenuating their stemness phenotype and inducing apoptosis and cell cycle arrest through the Erk1/2 and Akt pathways.
Wang L, Liu Y, Zhou Y, Wang J, Tu L, Sun Z, Wang X, Luo F
Journal of experimental & clinical cancer research : CR 2019 Feb 21;38(1):93
Journal of experimental & clinical cancer research : CR 2019 Feb 21;38(1):93
P53-induced miR-1249 inhibits tumor growth, metastasis, and angiogenesis by targeting VEGFA and HMGA2.
Chen X, Zeng K, Xu M, Liu X, Hu X, Xu T, He B, Pan Y, Sun H, Wang S
Cell death & disease 2019 Feb 12;10(2):131
Cell death & disease 2019 Feb 12;10(2):131
Upregulation of microRNA-133a and downregulation of connective tissue growth factor suppress cell proliferation, migration, and invasion in human glioma through the JAK/STAT signaling pathway.
Zhang P, Chen FZ, Jia QB, Hu DF
IUBMB life 2019 Dec;71(12):1857-1875
IUBMB life 2019 Dec;71(12):1857-1875
Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3Kα) against cutaneous melanoma.
Qin F, Wang Y, Jiang X, Wang Y, Zhang N, Wen X, Wang L, Jiang Q, He G
Journal of enzyme inhibition and medicinal chemistry 2019 Dec;34(1):909-926
Journal of enzyme inhibition and medicinal chemistry 2019 Dec;34(1):909-926
Knockdown of periostin attenuates 5/6 nephrectomy-induced intrarenal renin-angiotensin system activation, fibrosis, and inflammation in rats.
Bian X, Bai Y, Su X, Zhao G, Sun G, Li D
Journal of cellular physiology 2019 Dec;234(12):22857-22873
Journal of cellular physiology 2019 Dec;234(12):22857-22873
Histone deacetylases inhibitor MS-275 suppresses human esophageal squamous cell carcinoma cell growth and progression via the PI3K/Akt/mTOR pathway.
Ma S, Liu T, Xu L, Wang Y, Zhou J, Huang T, Li P, Liu H, Zhang Y, Zhou X, Cui Y, Zang X, Wang Y, Guan F
Journal of cellular physiology 2019 Dec;234(12):22400-22410
Journal of cellular physiology 2019 Dec;234(12):22400-22410
Downregulation of HDAC3 by ginsenoside Rg3 inhibits epithelial-mesenchymal transition of cutaneous squamous cell carcinoma through c-Jun acetylation.
Zhang L, Shan X, Chen Q, Xu D, Fan X, Yu M, Yan Q, Liu J
Journal of cellular physiology 2019 Dec;234(12):22207-22219
Journal of cellular physiology 2019 Dec;234(12):22207-22219
miR-451a inhibits cancer growth, epithelial-mesenchymal transition and induces apoptosis in papillary thyroid cancer by targeting PSMB8.
Fan X, Zhao Y
Journal of cellular and molecular medicine 2019 Dec;23(12):8067-8075
Journal of cellular and molecular medicine 2019 Dec;23(12):8067-8075
Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression.
Xu Q, Long Q, Zhu D, Fu D, Zhang B, Han L, Qian M, Guo J, Xu J, Cao L, Chin YE, Coppé JP, Lam EW, Campisi J, Sun Y
Aging cell 2019 Dec;18(6):e13027
Aging cell 2019 Dec;18(6):e13027
Six2 is negatively correlated with prognosis and facilitates epithelial-mesenchymal transition via TGF-β/Smad signal pathway in hepatocellular carcinoma.
Wan ZH, Ma YH, Jiang TY, Lin YK, Shi YY, Tan YX, Dong LW, Wang HY
Hepatobiliary & pancreatic diseases international : HBPD INT 2019 Dec;18(6):525-531
Hepatobiliary & pancreatic diseases international : HBPD INT 2019 Dec;18(6):525-531
Snail2 induced E-cadherin suppression and metastasis in lung carcinoma facilitated by G9a and HDACs.
Hu Y, Zheng Y, Dai M, Wu J, Yu B, Zhang H, Kong W, Wu H, Yu X
Cell adhesion & migration 2019 Dec;13(1):285-292
Cell adhesion & migration 2019 Dec;13(1):285-292
BECN1 promotes the migration of NSCLC cells through regulating the ubiquitination of Vimentin.
Cheng Z, Xin H, Han T
Cell adhesion & migration 2019 Dec;13(1):249-259
Cell adhesion & migration 2019 Dec;13(1):249-259
Ticagrelor and clopidogrel suppress NF-κB signaling pathway to alleviate LPS-induced dysfunction in vein endothelial cells.
Jia Z, Huang Y, Ji X, Sun J, Fu G
BMC cardiovascular disorders 2019 Dec 30;19(1):318
BMC cardiovascular disorders 2019 Dec 30;19(1):318
Hsa_circ_0006948 enhances cancer progression and epithelial-mesenchymal transition through the miR-490-3p/HMGA2 axis in esophageal squamous cell carcinoma.
Pan Z, Lin J, Wu D, He X, Wang W, Hu X, Zhang L, Wang M
Aging 2019 Dec 26;11(24):11937-11954
Aging 2019 Dec 26;11(24):11937-11954
Disruption of Cancer Metabolic SREBP1/miR-142-5p Suppresses Epithelial-Mesenchymal Transition and Stemness in Esophageal Carcinoma.
Huang CM, Huang CS, Hsu TN, Huang MS, Fong IH, Lee WH, Liu SC
Cells 2019 Dec 18;9(1)
Cells 2019 Dec 18;9(1)
PAMAM-cRGD mediating efficient siRNA delivery to spermatogonial stem cells.
Li T, Chen Q, Zheng Y, Zhang P, Chen X, Lu J, Lv Y, Sun S, Zeng W
Stem cell research & therapy 2019 Dec 18;10(1):399
Stem cell research & therapy 2019 Dec 18;10(1):399
A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice.
Quach C, Song Y, Guo H, Li S, Maazi H, Fung M, Sands N, O'Connell D, Restrepo-Vassalli S, Chai B, Nemecio D, Punj V, Akbari O, Idos GE, Mumenthaler SM, Wu N, Martin SE, Hagiya A, Hicks J, Cui H, Liang C
Nature communications 2019 Dec 12;10(1):5681
Nature communications 2019 Dec 12;10(1):5681
CLDN6 promotes tumor progression through the YAP1-snail1 axis in gastric cancer.
Yu S, Zhang Y, Li Q, Zhang Z, Zhao G, Xu J
Cell death & disease 2019 Dec 11;10(12):949
Cell death & disease 2019 Dec 11;10(12):949
Silencing TTK expression inhibits the proliferation and progression of prostate cancer.
Chen S, Wang J, Wang L, Peng H, Xiao L, Li C, Lin D, Yang K
Experimental cell research 2019 Dec 1;385(1):111669
Experimental cell research 2019 Dec 1;385(1):111669
MicroRNA-3666 inhibits lung cancer cell proliferation, migration, and invasiveness by targeting BPTF.
Pan L, Tang Z, Pan L, Tang R
Biochemistry and cell biology = Biochimie et biologie cellulaire 2019 Aug;97(4):415-422
Biochemistry and cell biology = Biochimie et biologie cellulaire 2019 Aug;97(4):415-422
Long non-coding RNA miR143HG predicts good prognosis and inhibits tumor multiplication and metastasis by suppressing mitogen-activated protein kinase and Wnt signaling pathways in hepatocellular carcinoma.
Lin X, Xiaoqin H, Jiayu C, Li F, Yue L, Ximing X
Hepatology research : the official journal of the Japan Society of Hepatology 2019 Aug;49(8):902-918
Hepatology research : the official journal of the Japan Society of Hepatology 2019 Aug;49(8):902-918
Intergrated analysis of ELMO1, serves as a link between tumour mutation burden and epithelial-mesenchymal transition in hepatocellular carcinoma.
Peng H, Zhang Y, Zhou Z, Guo Y, Huang X, Westover KD, Zhang Z, Chen B, Hua Y, Li S, Xu R, Lin N, Peng B, Shen S
EBioMedicine 2019 Aug;46:105-118
EBioMedicine 2019 Aug;46:105-118
miR-205-5p regulates epithelial-mesenchymal transition by targeting PTEN via PI3K/AKT signaling pathway in cisplatin-resistant nasopharyngeal carcinoma cells.
Zhang P, Lu X, Shi Z, Li X, Zhang Y, Zhao S, Liu H
Gene 2019 Aug 20;710:103-113
Gene 2019 Aug 20;710:103-113
miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt-β-catenin pathway.
Liu Q, Guan Y, Li Z, Wang Y, Liu Y, Cui R, Wang Y
Journal of experimental & clinical cancer research : CR 2019 Aug 16;38(1):358
Journal of experimental & clinical cancer research : CR 2019 Aug 16;38(1):358
EMT-related protein expression in polyploid giant cancer cells and their daughter cells with different passages after triptolide treatment.
Wang X, Zheng M, Fei F, Li C, Du J, Liu K, Li Y, Zhang S
Medical oncology (Northwood, London, England) 2019 Aug 12;36(9):82
Medical oncology (Northwood, London, England) 2019 Aug 12;36(9):82
TGF-β-mediated upregulation of brachyury contributes to constitutively up-regulated type I collagen expression in skin fibroblasts: possible role in systemic sclerosis.
Teng L, Yao G, Gao R, Wang Y, Lin W, Jin Y, Wang Y, Chen H, Wang Z, Chen J
European journal of dermatology : EJD 2019 Aug 1;29(4):359-365
European journal of dermatology : EJD 2019 Aug 1;29(4):359-365
Down-regulation of lncRNA-ATB inhibits epithelial-mesenchymal transition of breast cancer cells by increasing miR-141-3p expression.
Zhang Y, Li J, Jia S, Wang Y, Kang Y, Zhang W
Biochemistry and cell biology = Biochimie et biologie cellulaire 2019 Apr;97(2):193-200
Biochemistry and cell biology = Biochimie et biologie cellulaire 2019 Apr;97(2):193-200
LncRNA THOR increases osteosarcoma cell stemness and migration by enhancing SOX9 mRNA stability.
Wu H, He Y, Chen H, Liu Y, Wei B, Chen G, Lin H, Lin H
FEBS open bio 2019 Apr;9(4):781-790
FEBS open bio 2019 Apr;9(4):781-790
LncRNA H19 interacted with miR-130a-3p and miR-17-5p to modify radio-resistance and chemo-sensitivity of cardiac carcinoma cells.
Jia J, Zhang X, Zhan D, Li J, Li Z, Li H, Qian J
Cancer medicine 2019 Apr;8(4):1604-1618
Cancer medicine 2019 Apr;8(4):1604-1618
A mechanism of regucalcin knock-down in the promotion of proliferation and movement of human cervical cancer HeLa cells.
Li X, Huang Y, Wang P, Song W, Yao Q, Hu Q, Zhou S
Translational cancer research 2019 Apr;8(2):402-409
Translational cancer research 2019 Apr;8(2):402-409
Netrin‑1 interference potentiates epithelial‑to‑mesenchymal transition through the PI3K/AKT pathway under the hypoxic microenvironment conditions of non‑small cell lung cancer.
Jin X, Luan H, Chai H, Yan L, Zhang J, Wang Q, Cao L
International journal of oncology 2019 Apr;54(4):1457-1465
International journal of oncology 2019 Apr;54(4):1457-1465
Cathepsin B defines leader cells during the collective invasion of salivary adenoid cystic carcinoma.
Wu JS, Li ZF, Wang HF, Yu XH, Pang X, Wu JB, Wang SS, Zhang M, Yang X, Cao MX, Tang YJ, Liang XH, Zheng M, Tang YL
International journal of oncology 2019 Apr;54(4):1233-1244
International journal of oncology 2019 Apr;54(4):1233-1244
Effects of SIRT1 silencing on viability, invasion and metastasis of human glioma cell lines.
Li Y, Chen X, Cui Y, Wei Q, Chen S, Wang X
Oncology letters 2019 Apr;17(4):3701-3708
Oncology letters 2019 Apr;17(4):3701-3708
Bone marrow mesenchymal stem cells suppress growth and promote the apoptosis of glioma U251 cells through downregulation of the PI3K/AKT signaling pathway.
Lu L, Chen G, Yang J, Ma Z, Yang Y, Hu Y, Lu Y, Cao Z, Wang Y, Wang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108625
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108625
Network-pharmacology-based identification of caveolin-1 as a key target of Oldenlandia diffusa to suppress breast cancer metastasis.
Yang B, Wang N, Wang S, Li X, Zheng Y, Li M, Song J, Zhang F, Mei W, Lin Y, Wang Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108607
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108607
Knockdown on aPKC-ι inhibits epithelial-mesenchymal transition, migration and invasion of colorectal cancer cells through Rac1-JNK pathway.
Du GS, Qiu Y, Wang WS, Peng K, Zhang ZC, Li XS, Xiao WD, Yang H
Experimental and molecular pathology 2019 Apr;107:57-67
Experimental and molecular pathology 2019 Apr;107:57-67
GTSE1 is involved in breast cancer progression in p53 mutation-dependent manner.
Lin F, Xie YJ, Zhang XK, Huang TJ, Xu HF, Mei Y, Liang H, Hu H, Lin ST, Luo FF, Lang YH, Peng LX, Qian CN, Huang BJ
Journal of experimental & clinical cancer research : CR 2019 Apr 8;38(1):152
Journal of experimental & clinical cancer research : CR 2019 Apr 8;38(1):152
The PAX6-ZEB2 axis promotes metastasis and cisplatin resistance in non-small cell lung cancer through PI3K/AKT signaling.
Wu DM, Zhang T, Liu YB, Deng SH, Han R, Liu T, Li J, Xu Y
Cell death & disease 2019 Apr 25;10(5):349
Cell death & disease 2019 Apr 25;10(5):349
Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance.
Li S, Song Y, Quach C, Guo H, Jang GB, Maazi H, Zhao S, Sands NA, Liu Q, In GK, Peng D, Yuan W, Machida K, Yu M, Akbari O, Hagiya A, Yang Y, Punj V, Tang L, Liang C
Nature communications 2019 Apr 12;10(1):1693
Nature communications 2019 Apr 12;10(1):1693
S100A4-MYH9 Axis Promote Migration and Invasion of Gastric Cancer Cells by Inducing TGF-β-Mediated Epithelial-Mesenchymal Transition.
Li F, Shi J, Xu Z, Yao X, Mou T, Yu J, Liu H, Li G
Journal of Cancer 2018;9(21):3839-3849
Journal of Cancer 2018;9(21):3839-3849
AMPH-1 is critical for breast cancer progression.
Chen Y, Liu J, Li L, Xia H, Lin Z, Zhong T
Journal of Cancer 2018;9(12):2175-2182
Journal of Cancer 2018;9(12):2175-2182
Cisatracurium Retards Cell Migration and Invasion Upon Upregulation of p53 and Inhibits the Aggressiveness of Colorectal Cancer.
Yabasin IB, Sanches JGP, Ibrahim MM, Huidan J, Williams W, Lu ZL, Wen Q
Frontiers in physiology 2018;9:941
Frontiers in physiology 2018;9:941
Keratinocytes Isolated From Individual Cleft Lip/Palate Patients Display Variations in Their Differentiation Potential in vitro.
Degen M, Wiederkehr A, La Scala GC, Carmann C, Schnyder I, Katsaros C
Frontiers in physiology 2018;9:1703
Frontiers in physiology 2018;9:1703
MicroRNA-506 suppresses invasiveness and metastasis of human hepatocellular carcinoma cells by targeting IL8.
Wang Z, Si M, Yang N, Zhang H, Fu Y, Yan K, Zong Y, Zhu N, Wei Y
American journal of cancer research 2018;8(8):1586-1594
American journal of cancer research 2018;8(8):1586-1594
Add-On therapy with Chinese herb medicine Bo-Er-Ning capsule (BENC) improves outcomes of gastric cancer patients: a randomized clinical trial followed with bioinformatics-assisted mechanism study.
Pan B, Zang J, He J, Wang Z, Liu L
American journal of cancer research 2018;8(6):1090-1105
American journal of cancer research 2018;8(6):1090-1105
miR-200c/141 Regulates Breast Cancer Stem Cell Heterogeneity via Targeting HIPK1/β-Catenin Axis.
Liu B, Du R, Zhou L, Xu J, Chen S, Chen J, Yang X, Liu DX, Shao ZM, Zhang L, Yu Z, Xie N, Guan JL, Liu S
Theranostics 2018;8(21):5801-5813
Theranostics 2018;8(21):5801-5813
Tip60 Suppresses Cholangiocarcinoma Proliferation and Metastasis via PI3k-AKT.
Zhang Y, Ji G, Han S, Shao Z, Lu Z, Huo L, Zhang J, Yang R, Feng Q, Shen H, Wang H, Li X
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(2):612-628
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(2):612-628
Formation of Human Colonic Crypt Array by Application of Chemical Gradients Across a Shaped Epithelial Monolayer.
Wang Y, Kim R, Gunasekara DB, Reed MI, DiSalvo M, Nguyen DL, Bultman SJ, Sims CE, Magness ST, Allbritton NL
Cellular and molecular gastroenterology and hepatology 2018;5(2):113-130
Cellular and molecular gastroenterology and hepatology 2018;5(2):113-130
The Natural Compound Myricetin Effectively Represses the Malignant Progression of Prostate Cancer by Inhibiting PIM1 and Disrupting the PIM1/CXCR4 Interaction.
Ye C, Zhang C, Huang H, Yang B, Xiao G, Kong D, Tian Q, Song Q, Song Y, Tan H, Wang Y, Zhou T, Zi X, Sun Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(3):1230-1244
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(3):1230-1244
MiR-598 Suppresses Invasion and Migration by Negative Regulation of Derlin-1 and Epithelial-Mesenchymal Transition in Non-Small Cell Lung Cancer.
Yang F, Wei K, Qin Z, Liu W, Shao C, Wang C, Ma L, Xie M, Shu Y, Shen H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(1):245-256
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(1):245-256
C/D-Box Snord105b Promotes Tumorigenesis in Gastric Cancer via ALDOA/C-Myc Pathway.
Zhang C, Zhao LM, Wu H, Tian G, Dai SL, Zhao RY, Shan BE
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;45(6):2471-2482
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;45(6):2471-2482
Simulated Cholinergic Reinnervation of β (INS-1) Cells: Antidiabetic Utility of Heterotypic Pseudoislets Containing β Cell and Cholinergic Cell.
Jiao A, Li F, Zhang C, Lv W, Chen B, Zhang J
International journal of endocrinology 2018;2018:1505307
International journal of endocrinology 2018;2018:1505307
Silencing Formin-like 2 inhibits growth and metastasis of gastric cancer cells through suppressing internalization of integrins.
Zhong B, Wang K, Xu H, Kong F
Cancer cell international 2018;18:79
Cancer cell international 2018;18:79
Tumor-associated macrophages derived CCL18 promotes metastasis in squamous cell carcinoma of the head and neck.
She L, Qin Y, Wang J, Liu C, Zhu G, Li G, Wei M, Chen C, Liu G, Zhang D, Chen X, Wang Y, Qiu Y, Tian Y, Zhang X, Liu Y, Huang D
Cancer cell international 2018;18:120
Cancer cell international 2018;18:120
NANOGP8 is the key regulator of stemness, EMT, Wnt pathway, chemoresistance, and other malignant phenotypes in gastric cancer cells.
Ma X, Wang B, Wang X, Luo Y, Fan W
PloS one 2018;13(4):e0192436
PloS one 2018;13(4):e0192436
Overexpression of FAM3C protein as a novel biomarker for epithelial-mesenchymal transition and poor outcome in gastric cancer.
Yin S, Chen F, Ye P, Yang G
International journal of clinical and experimental pathology 2018;11(8):4247-4256
International journal of clinical and experimental pathology 2018;11(8):4247-4256
Overexpression of TEAD4 correlates with poor prognosis of glioma and promotes cell invasion.
Xu A, Wang X, Zeng Y, Zhou M, Yi R, Wu Z, Lin J, Song Y
International journal of clinical and experimental pathology 2018;11(10):4827-4835
International journal of clinical and experimental pathology 2018;11(10):4827-4835
EDIL3 depletion suppress epithelial-mesenchymal transition of lens epithelial cells via transforming growth factor β pathway.
Zhang R, Wei YH, Zhao CY, Song HY, Shen N, Cui X, Gao X, Qi ZT, Zhong M, Shen W
International journal of ophthalmology 2018;11(1):18-24
International journal of ophthalmology 2018;11(1):18-24
KIAA1199 overexpression is associated with abnormal expression of EMT markers and is a novel independent prognostic biomarker for hepatocellular carcinoma.
Jiang Z, Zhai X, Shi B, Luo D, Jin B
OncoTargets and therapy 2018;11:8341-8348
OncoTargets and therapy 2018;11:8341-8348
Contribution of dysregulated circRNA_100876 to proliferation and metastasis of esophageal squamous cell carcinoma.
Cao S, Chen G, Yan L, Li L, Huang X
OncoTargets and therapy 2018;11:7385-7394
OncoTargets and therapy 2018;11:7385-7394
Phenformin and metformin inhibit growth and migration of LN229 glioma cells in vitro and in vivo.
Wang Y, Meng Y, Zhang S, Wu H, Yang D, Nie C, Hu Q
OncoTargets and therapy 2018;11:6039-6048
OncoTargets and therapy 2018;11:6039-6048
SIRT1 overexpression protects non-small cell lung cancer cells against osteopontin-induced epithelial-mesenchymal transition by suppressing NF-κB signaling.
Li X, Jiang Z, Li X, Zhang X
OncoTargets and therapy 2018;11:1157-1171
OncoTargets and therapy 2018;11:1157-1171
Interaction with SP1, but not binding to the E-box motifs, is responsible for BHLHE40/DEC1-induced transcriptional suppression of CLDN1 and cell invasion in MCF-7 cells.
Zheng Q, Wang C, Wang L, Zhang D, Liu N, Ming X, Zhou H, Guli Q, Liu Y
Molecular carcinogenesis 2018 Sep;57(9):1116-1129
Molecular carcinogenesis 2018 Sep;57(9):1116-1129
Polyphyllin I inhibits invasion and epithelial-mesenchymal transition via CIP2A/PP2A/ERK signaling in prostate cancer.
Liu X, Sun Z, Deng J, Liu J, Ma K, Si Y, Zhang T, Feng T, Liu Y, Tan Y
International journal of oncology 2018 Sep;53(3):1279-1288
International journal of oncology 2018 Sep;53(3):1279-1288
Stromal expression of JNK1 and VDR is associated with the prognosis of esophageal squamous cell carcinoma.
Bao Y, Zhang S, Guo Y, Wei X, Zhang Y, Yang Y, Zhang H, Ma M, Yang W
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2018 Sep;20(9):1185-1195
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2018 Sep;20(9):1185-1195
Tanshinone IIA inhibits cervix carcinoma stem cells migration and invasion via inhibiting YAP transcriptional activity.
Qin J, Shi H, Xu Y, Zhao F, Wang Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Sep;105:758-765
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Sep;105:758-765
Effect of simvastatin and microRNA-21 inhibitor on metastasis and progression of human salivary adenoid cystic carcinoma.
Wang C, Li T, Yan F, Cai W, Zheng J, Jiang X, Sun J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Sep;105:1054-1061
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Sep;105:1054-1061
SNORA42 enhances prostate cancer cell viability, migration and EMT and is correlated with prostate cancer poor prognosis.
Yi C, Wan X, Zhang Y, Fu F, Zhao C, Qin R, Wu H, Li Y, Huang Y
The international journal of biochemistry & cell biology 2018 Sep;102:138-150
The international journal of biochemistry & cell biology 2018 Sep;102:138-150
MiR-455-3p suppresses renal fibrosis through repression of ROCK2 expression in diabetic nephropathy.
Wu J, Liu J, Ding Y, Zhu M, Lu K, Zhou J, Xie X, Xu Y, Shen X, Chen Y, Shao X, Zhu C
Biochemical and biophysical research communications 2018 Sep 5;503(2):977-983
Biochemical and biophysical research communications 2018 Sep 5;503(2):977-983
S3I-201 ameliorates tubulointerstitial lesion of the kidneys in MRL/lpr mice.
Du Y, Zhang W, Liu S, Feng X, Gao F, Liu Q
Biochemical and biophysical research communications 2018 Sep 3;503(1):177-180
Biochemical and biophysical research communications 2018 Sep 3;503(1):177-180
DDX5 promotes hepatocellular carcinoma tumorigenesis via Akt signaling pathway.
Xue Y, Jia X, Li L, Dong X, Ling J, Yuan J, Li Q
Biochemical and biophysical research communications 2018 Sep 18;503(4):2885-2891
Biochemical and biophysical research communications 2018 Sep 18;503(4):2885-2891
TGF-β-mediated exosomal lnc-MMP2-2 regulates migration and invasion of lung cancer cells to the vasculature by promoting MMP2 expression.
Wu DM, Deng SH, Liu T, Han R, Zhang T, Xu Y
Cancer medicine 2018 Oct;7(10):5118-5129
Cancer medicine 2018 Oct;7(10):5118-5129
MiR-616-3p modulates cell proliferation and migration through targeting tissue factor pathway inhibitor 2 in preeclampsia.
Xu Y, Wu D, Jiang Z, Zhang Y, Wang S, Ma Z, Hui B, Wang J, Qian W, Ge Z, Sun L
Cell proliferation 2018 Oct;51(5):e12490
Cell proliferation 2018 Oct;51(5):e12490
Selenium (Na(2)SeO(3)) Upregulates Expression of Immune Genes and Blood-Testis Barrier Constituent Proteins of Bovine Sertoli Cell In Vitro.
Adegoke EO, Wang X, Wang H, Wang C, Zhang H, Zhang G
Biological trace element research 2018 Oct;185(2):332-343
Biological trace element research 2018 Oct;185(2):332-343
Low-Dose Radiation Enhanced Inhibition of Breast Tumor Xenograft and Reduced Myocardial Injury Induced by Doxorubicin.
Jiang X, Du Y, Meng X, Zhang H, Zhao D, Zhao L, Chen J, Xiao S, Jiang H
Dose-response : a publication of International Hormesis Society 2018 Oct-Dec;16(4):1559325818813061
Dose-response : a publication of International Hormesis Society 2018 Oct-Dec;16(4):1559325818813061
High expression of WNT7A predicts poor prognosis and promote tumor metastasis in pancreatic ductal adenocarcinoma.
Wu DJ, Jiang YS, He RZ, Tao LY, Yang MW, Fu XL, Yang JY, Zhu K
Scientific reports 2018 Oct 25;8(1):15792
Scientific reports 2018 Oct 25;8(1):15792
Periostin secreted by cancer-associated fibroblasts promotes cancer stemness in head and neck cancer by activating protein tyrosine kinase 7.
Yu B, Wu K, Wang X, Zhang J, Wang L, Jiang Y, Zhu X, Chen W, Yan M
Cell death & disease 2018 Oct 22;9(11):1082
Cell death & disease 2018 Oct 22;9(11):1082
Reduced graphene oxide triggered epithelial-mesenchymal transition in A549 cells.
Liao Y, Wang W, Huang X, Sun Y, Tian S, Cai P
Scientific reports 2018 Oct 12;8(1):15188
Scientific reports 2018 Oct 12;8(1):15188
DNA-methylation-mediated silencing of miR-486-5p promotes colorectal cancer proliferation and migration through activation of PLAGL2/IGF2/β-catenin signal pathways.
Liu X, Chen X, Zeng K, Xu M, He B, Pan Y, Sun H, Pan B, Xu X, Xu T, Hu X, Wang S
Cell death & disease 2018 Oct 10;9(10):1037
Cell death & disease 2018 Oct 10;9(10):1037
Knockdown of NLRP3 alleviates high glucose or TGFB1-induced EMT in human renal tubular cells.
Song S, Qiu D, Luo F, Wei J, Wu M, Wu H, Du C, Du Y, Ren Y, Chen N, Duan H, Shi Y
Journal of molecular endocrinology 2018 Oct 1;61(3):101-113
Journal of molecular endocrinology 2018 Oct 1;61(3):101-113
Identification and characterization of a highly metastatic epithelial cancer cell line from rat tongue cancer.
Qin X, Yan M, Li R, Ye D, Zhang J, Xu Q, Feng Y, Sun Q, Jiang C, Chen W
Archives of oral biology 2018 Nov;95:58-67
Archives of oral biology 2018 Nov;95:58-67
LncRNA UCA1 is necessary for TGF-β-induced epithelial-mesenchymal transition and stemness via acting as a ceRNA for Slug in glioma cells.
Li Z, Liu H, Zhong Q, Wu J, Tang Z
FEBS open bio 2018 Nov;8(11):1855-1865
FEBS open bio 2018 Nov;8(11):1855-1865
RNA interference of long noncoding RNA HOTAIR suppresses autophagy and promotes apoptosis and sensitivity to cisplatin in oral squamous cell carcinoma.
Wang X, Liu W, Wang P, Li S
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2018 Nov;47(10):930-937
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2018 Nov;47(10):930-937
MiR-122 inhibits epithelial mesenchymal transition by regulating P4HA1 in ovarian cancer cells.
Duan Y, Dong Y, Dang R, Hu Z, Yang Y, Hu Y, Cheng J
Cell biology international 2018 Nov;42(11):1564-1574
Cell biology international 2018 Nov;42(11):1564-1574
Abrogation of glutathione peroxidase-1 drives EMT and chemoresistance in pancreatic cancer by activating ROS-mediated Akt/GSK3β/Snail signaling.
Meng Q, Shi S, Liang C, Liang D, Hua J, Zhang B, Xu J, Yu X
Oncogene 2018 Nov;37(44):5843-5857
Oncogene 2018 Nov;37(44):5843-5857
Silencing of rhomboid domain containing 1 to inhibit the metastasis of human breast cancer cells in vitro.
Huang C, Ji X, Peng Y, Wu M, Wu W, Luo Y, Cheng G, Zhu Y
Iranian journal of basic medical sciences 2018 Nov;21(11):1161-1166
Iranian journal of basic medical sciences 2018 Nov;21(11):1161-1166
A gene mutation in RNA-binding protein 10 is associated with lung adenocarcinoma progression and poor prognosis.
Yin LL, Wen XM, Li M, Xu YM, Zhao XF, Li J, Wang XW
Oncology letters 2018 Nov;16(5):6283-6292
Oncology letters 2018 Nov;16(5):6283-6292
Isoliquiritigenin inhibits cell proliferation and migration through the PI3K/AKT signaling pathway in A549 lung cancer cells.
Tian T, Sun J, Wang J, Liu Y, Liu H
Oncology letters 2018 Nov;16(5):6133-6139
Oncology letters 2018 Nov;16(5):6133-6139
Effects of PLK1 on proliferation, invasion and metastasis of gastric cancer cells through epithelial-mesenchymal transition.
Song R, Hou G, Yang J, Yuan J, Wang C, Chai T, Liu Z
Oncology letters 2018 Nov;16(5):5739-5744
Oncology letters 2018 Nov;16(5):5739-5744
Toll-like receptor 4 shRNA attenuates lipopolysaccharide-induced epithelial-mesenchymal transition of intrahepatic biliary epithelial cells in rats.
Tang S, Jiang X, Wu L, Chen S, Chen L, Jiang J, Yan P, Wang F, Tu K, Wang D, Gu J, Zhao L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1210-1217
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Nov;107:1210-1217
Combination Therapy with DETA/NO and Clopidogrel Inhibits Metastasis in Murine Mammary Gland Cancer Models via Improved Vasoprotection.
Porshneva K, Papiernik D, Psurski M, Nowak M, Matkowski R, Ekiert M, Milczarek M, Banach J, Jarosz J, Wietrzyk J
Molecular pharmaceutics 2018 Nov 5;15(11):5277-5290
Molecular pharmaceutics 2018 Nov 5;15(11):5277-5290
Abnormally elevated USP37 expression in breast cancer stem cells regulates stemness, epithelial-mesenchymal transition and cisplatin sensitivity.
Qin T, Li B, Feng X, Fan S, Liu L, Liu D, Mao J, Lu Y, Yang J, Yu X, Zhang Q, Zhang J, Song B, Li M, Li L
Journal of experimental & clinical cancer research : CR 2018 Nov 27;37(1):287
Journal of experimental & clinical cancer research : CR 2018 Nov 27;37(1):287
The HER4-YAP1 axis promotes trastuzumab resistance in HER2-positive gastric cancer by inducing epithelial and mesenchymal transition.
Shi J, Li F, Yao X, Mou T, Xu Z, Han Z, Chen S, Li W, Yu J, Qi X, Liu H, Li G
Oncogene 2018 May;37(22):3022-3038
Oncogene 2018 May;37(22):3022-3038
CD74-ROS1 G2032R mutation transcriptionally up-regulates Twist1 in non-small cell lung cancer cells leading to increased migration, invasion, and resistance to crizotinib.
Gou W, Zhou X, Liu Z, Wang L, Shen J, Xu X, Li Z, Zhai X, Zuo D, Wu Y
Cancer letters 2018 May 28;422:19-28
Cancer letters 2018 May 28;422:19-28
Krüppel-like Factor 4 Suppresses Serine/Threonine Kinase 33 Activation and Metastasis of Gastric Cancer through Reversing Epithelial-Mesenchymal Transition.
Kong F, Sun T, Kong X, Xie D, Li Z, Xie K
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 May 15;24(10):2440-2451
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 May 15;24(10):2440-2451
Silencing of lncRNA ZFAS1 inhibits malignancies by blocking Wnt/β-catenin signaling in gastric cancer cells.
Xu W, He L, Li Y, Tan Y, Zhang F, Xu H
Bioscience, biotechnology, and biochemistry 2018 Mar;82(3):456-465
Bioscience, biotechnology, and biochemistry 2018 Mar;82(3):456-465
Dysregulated Expression of RPS4Y1 (Ribosomal Protein S4, Y-Linked 1) Impairs STAT3 (Signal Transducer and Activator of Transcription 3) Signaling to Suppress Trophoblast Cell Migration and Invasion in Preeclampsia.
Chen X, Tong C, Li H, Peng W, Li R, Luo X, Ge H, Ran Y, Li Q, Liu Y, Xiong X, Bai Y, Zhang H, Baker PN, Liu X, Qi H
Hypertension (Dallas, Tex. : 1979) 2018 Mar;71(3):481-490
Hypertension (Dallas, Tex. : 1979) 2018 Mar;71(3):481-490
NEK2 promotes hepatocellular carcinoma migration and invasion through modulation of the epithelial-mesenchymal transition.
Zhang Y, Wang W, Wang Y, Huang X, Zhang Z, Chen B, Xie W, Li S, Shen S, Peng B
Oncology reports 2018 Mar;39(3):1023-1033
Oncology reports 2018 Mar;39(3):1023-1033
Short interfering RNA-mediated silencing of actin-related protein 2/3 complex subunit 4 inhibits the migration of SW620 human colorectal cancer cells.
Su X, Wang S, Huo Y, Yang C
Oncology letters 2018 Mar;15(3):2847-2854
Oncology letters 2018 Mar;15(3):2847-2854
Targeting of NT5E by miR-30b and miR-340 attenuates proliferation, invasion and migration of gallbladder carcinoma.
Wang N, Xiang X, Chen K, Liu P, Zhu A
Biochimie 2018 Mar;146:56-67
Biochimie 2018 Mar;146:56-67
MicroRNA-140 Inhibits the Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer.
Li J, Zou K, Yu L, Zhao W, Lu Y, Mao J, Wang B, Wang L, Fan S, Song B, Li L
Molecular therapy. Nucleic acids 2018 Mar 2;10:426-437
Molecular therapy. Nucleic acids 2018 Mar 2;10:426-437
SEC-induced activation of ANXA7 GTPase suppresses prostate cancer metastasis.
Liu S, Li X, Lin Z, Su L, Yan S, Zhao B, Miao J
Cancer letters 2018 Mar 1;416:11-23
Cancer letters 2018 Mar 1;416:11-23
Systematic analyses reveal long non-coding RNA (PTAF)-mediated promotion of EMT and invasion-metastasis in serous ovarian cancer.
Liang H, Zhao X, Wang C, Sun J, Chen Y, Wang G, Fang L, Yang R, Yu M, Gu Y, Shan H
Molecular cancer 2018 Jun 21;17(1):96
Molecular cancer 2018 Jun 21;17(1):96
LncRNA SNHG7 sponges miR-216b to promote proliferation and liver metastasis of colorectal cancer through upregulating GALNT1.
Shan Y, Ma J, Pan Y, Hu J, Liu B, Jia L
Cell death & disease 2018 Jun 18;9(7):722
Cell death & disease 2018 Jun 18;9(7):722
Matrine inhibits the invasive and migratory properties of human hepatocellular carcinoma by regulating epithelial‑mesenchymal transition.
Wang Y, Zhang S, Liu J, Fang B, Yao J, Cheng B
Molecular medicine reports 2018 Jul;18(1):911-919
Molecular medicine reports 2018 Jul;18(1):911-919
Deacetylmycoepoxydiene is an agonist of Rac1, and simultaneously induces autophagy and apoptosis.
Xie W, Zhang W, Sun M, Lu C, Shen Y
Applied microbiology and biotechnology 2018 Jul;102(14):5965-5975
Applied microbiology and biotechnology 2018 Jul;102(14):5965-5975
Formation of arrays of planar, murine, intestinal crypts possessing a stem/proliferative cell compartment and differentiated cell zone.
Kim R, Wang Y, Hwang SJ, Attayek PJ, Smiddy NM, Reed MI, Sims CE, Allbritton NL
Lab on a chip 2018 Jul 24;18(15):2202-2213
Lab on a chip 2018 Jul 24;18(15):2202-2213
RHBDF1 regulates APC-mediated stimulation of the epithelial-to-mesenchymal transition and proliferation of colorectal cancer cells in part via the Wnt/β-catenin signalling pathway.
Yuan H, Wei R, Xiao Y, Song Y, Wang J, Yu H, Fang T, Xu W, Mao S
Experimental cell research 2018 Jul 1;368(1):24-36
Experimental cell research 2018 Jul 1;368(1):24-36
ADAM12 induces EMT and promotes cell migration, invasion and proliferation in pituitary adenomas via EGFR/ERK signaling pathway.
Wang J, Zhang Z, Li R, Mao F, Sun W, Chen J, Zhang H, Bartsch JW, Shu K, Lei T
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:1066-1077
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:1066-1077
β-Arrestin-1 deficiency ameliorates renal interstitial fibrosis by blocking Wnt1/β-catenin signaling in mice.
Xu H, Li Q, Liu J, Zhu J, Li L, Wang Z, Zhang Y, Sun Y, Sun J, Wang R, Yi F
Journal of molecular medicine (Berlin, Germany) 2018 Jan;96(1):97-109
Journal of molecular medicine (Berlin, Germany) 2018 Jan;96(1):97-109
Unfavorable effect of calcitriol and its low-calcemic analogs on metastasis of 4T1 mouse mammary gland cancer.
Anisiewicz A, Pawlik A, Filip-Psurska B, Turlej E, Dzimira S, Milczarek M, Gdesz K, Papiernik D, Jarosz J, Kłopotowska D, Kutner A, Mazur A, Wietrzyk J
International journal of oncology 2018 Jan;52(1):103-126
International journal of oncology 2018 Jan;52(1):103-126
PLCD3, a flotillin2-interacting protein, is involved in proliferation, migration and invasion of nasopharyngeal carcinoma cells.
Liu W, Liu X, Wang L, Zhu B, Zhang C, Jia W, Zhu H, Liu X, Zhong M, Xie D, Liu Y, Li S, Shi J, Lin J, Xia X, Jiang X, Ren C
Oncology reports 2018 Jan;39(1):45-52
Oncology reports 2018 Jan;39(1):45-52
Silencing of CEMIP suppresses Wnt/β-catenin/Snail signaling transduction and inhibits EMT program of colorectal cancer cells.
Liang G, Fang X, Yang Y, Song Y
Acta histochemica 2018 Jan;120(1):56-63
Acta histochemica 2018 Jan;120(1):56-63
Downregulation of N(6)-methyladenosine binding YTHDF2 protein mediated by miR-493-3p suppresses prostate cancer by elevating N(6)-methyladenosine levels.
Li J, Meng S, Xu M, Wang S, He L, Xu X, Wang X, Xie L
Oncotarget 2018 Jan 9;9(3):3752-3764
Oncotarget 2018 Jan 9;9(3):3752-3764
Dewetting of Thin Liquid Films Surrounding Air Bubbles in Microchannels.
Khodaparast S, Atasi O, Deblais A, Scheid B, Stone HA
Langmuir : the ACS journal of surfaces and colloids 2018 Jan 30;34(4):1363-1370
Langmuir : the ACS journal of surfaces and colloids 2018 Jan 30;34(4):1363-1370
Downregulation of annexin A3 inhibits tumor metastasis and decreases drug resistance in breast cancer.
Du R, Liu B, Zhou L, Wang D, He X, Xu X, Zhang L, Niu C, Liu S
Cell death & disease 2018 Jan 26;9(2):126
Cell death & disease 2018 Jan 26;9(2):126
PLZF inhibits proliferation and metastasis of gallbladder cancer by regulating IFIT2.
Shen H, Zhan M, Zhang Y, Huang S, Xu S, Huang X, He M, Yao Y, Man M, Wang J
Cell death & disease 2018 Jan 22;9(2):71
Cell death & disease 2018 Jan 22;9(2):71
Increased Expression of Cullin 3 in Nasopharyngeal Carcinoma and Knockdown Inhibits Proliferation and Invasion.
Zeng R, Tan G, Li W, Ma Y
Oncology research 2018 Jan 19;26(1):111-122
Oncology research 2018 Jan 19;26(1):111-122
HOXC8 promotes proliferation and migration through transcriptional up-regulation of TGFβ1 in non-small cell lung cancer.
Liu H, Zhang M, Xu S, Zhang J, Zou J, Yang C, Zhang Y, Gong C, Kai Y, Li Y
Oncogenesis 2018 Jan 17;7(2):1
Oncogenesis 2018 Jan 17;7(2):1
Up-regulated lnc-SNHG1 contributes to osteosarcoma progression through sequestration of miR-577 and activation of WNT2B/Wnt/β-catenin pathway.
Jiang Z, Jiang C, Fang J
Biochemical and biophysical research communications 2018 Jan 1;495(1):238-245
Biochemical and biophysical research communications 2018 Jan 1;495(1):238-245
UNC0638, a G9a inhibitor, suppresses epithelial‑mesenchymal transition‑mediated cellular migration and invasion in triple negative breast cancer.
Liu XR, Zhou LH, Hu JX, Liu LM, Wan HP, Zhang XQ
Molecular medicine reports 2018 Feb;17(2):2239-2244
Molecular medicine reports 2018 Feb;17(2):2239-2244
Carnosol-mediated Sirtuin 1 activation inhibits Enhancer of Zeste Homolog 2 to attenuate liver fibrosis.
Zhao H, Wang Z, Tang F, Zhao Y, Feng D, Li Y, Hu Y, Wang C, Zhou J, Tian X, Yao J
Pharmacological research 2018 Feb;128:327-337
Pharmacological research 2018 Feb;128:327-337
Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial-mesenchymal transition and stemness.
Wang J, Tian L, Khan MN, Zhang L, Chen Q, Zhao Y, Yan Q, Fu L, Liu J
Cancer letters 2018 Feb 28;415:73-85
Cancer letters 2018 Feb 28;415:73-85
Collagen-based three-dimensional culture microenvironment promotes epithelial to mesenchymal transition and drug resistance of human ovarian cancer in vitro.
Liu M, Zhang X, Long C, Xu H, Cheng X, Chang J, Zhang C, Zhang C, Wang X
RSC advances 2018 Feb 23;8(16):8910-8919
RSC advances 2018 Feb 23;8(16):8910-8919
PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis.
Zhao B, Liu L, Mao J, Zhang Z, Wang Q, Li Q
Cell death & disease 2018 Feb 22;9(3):307
Cell death & disease 2018 Feb 22;9(3):307
PMLIV overexpression promotes TGF-β-associated epithelial-mesenchymal transition and migration in MCF-7 cancer cells.
Liu Y, Wang JX, Huang D, Wang B, Li LL, Li XX, Ni P, Dong XL, Xia W, Yu CX, Xu WL, Chu WF, Zhao D
Journal of cellular physiology 2018 Dec;233(12):9575-9583
Journal of cellular physiology 2018 Dec;233(12):9575-9583
Glutathione reductase-mediated thiol oxidative stress suppresses metastasis of murine melanoma cells.
Li X, Wu J, Zhang X, Chen W
Free radical biology & medicine 2018 Dec;129:256-267
Free radical biology & medicine 2018 Dec;129:256-267
A CREB1/miR-433 reciprocal feedback loop modulates proliferation and metastasis in colorectal cancer.
Yan L, You WQ, Sheng NQ, Gong JF, Hu LD, Tan GW, Chen HQ, Wang ZG
Aging 2018 Dec 6;10(12):3774-3793
Aging 2018 Dec 6;10(12):3774-3793
Salinomycin suppresses cancer cell stemness and attenuates TGF-β-induced epithelial-mesenchymal transition of renal cell carcinoma cells.
Liu L, Wang Q, Mao J, Qin T, Sun Y, Yang J, Han Y, Li L, Li Q
Chemico-biological interactions 2018 Dec 25;296:145-153
Chemico-biological interactions 2018 Dec 25;296:145-153
Synthesis and Discovery Novel Anti-Cancer Stem Cells Compounds Derived from the Natural Triterpenoic Acids.
Liu X, Li B, Zhang Z, Wei Y, Xu Z, Qin S, Liu N, Zhao R, Peng J, Yang G, Qi M, Liu T, Xie M, Liu S, Gao X, Lu C, Zhu L, Long X, Kang H, Sun T, Zhou H, Wei M, Yang G, Yang C
Journal of medicinal chemistry 2018 Dec 13;61(23):10814-10833
Journal of medicinal chemistry 2018 Dec 13;61(23):10814-10833
Epigenetic suppression of E-cadherin expression by Snail2 during the metastasis of colorectal cancer.
Hu Y, Dai M, Zheng Y, Wu J, Yu B, Zhang H, Kong W, Wu H, Yu X
Clinical epigenetics 2018 Dec 12;10(1):154
Clinical epigenetics 2018 Dec 12;10(1):154
Mitochondrial cytochrome P450 (CYP) 1B1 is responsible for melatonin-induced apoptosis in neural cancer cells.
Yu Z, Tian X, Peng Y, Sun Z, Wang C, Tang N, Li B, Jian Y, Wang W, Huo X, Ma X
Journal of pineal research 2018 Aug;65(1):e12478
Journal of pineal research 2018 Aug;65(1):e12478
Circadian regulator NR1D2 regulates glioblastoma cell proliferation and motility.
Yu M, Li W, Wang Q, Wang Y, Lu F
Oncogene 2018 Aug;37(35):4838-4853
Oncogene 2018 Aug;37(35):4838-4853
LncRNA BDNF-AS inhibits proliferation, migration, invasion and EMT in oesophageal cancer cells by targeting miR-214.
Zhao H, Diao C, Wang X, Xie Y, Liu Y, Gao X, Han J, Li S
Journal of cellular and molecular medicine 2018 Aug;22(8):3729-3739
Journal of cellular and molecular medicine 2018 Aug;22(8):3729-3739
Suppressed epithelial-mesenchymal transition and cancer stem cell properties mediate the anti-cancer effects of ethyl pyruvate via regulation of the AKT/nuclear factor-κB pathway in prostate cancer cells.
Huang B, Lv DJ, Wang C, Shu FP, Gong ZC, Xie T, Yu YZ, Song XL, Xie JJ, Li S, Liu YM, Qi H, Zhao SC
Oncology letters 2018 Aug;16(2):2271-2278
Oncology letters 2018 Aug;16(2):2271-2278
The gastric mucosal protective effects of astragaloside IV in mnng-induced GPL rats.
Cai T, Zhang C, Zhao Z, Li S, Cai H, Chen X, Cai D, Liu W, Yan Y, Xie K, Pan H, Zeng X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Aug;104:291-299
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Aug;104:291-299
Phosphoglycerate Mutase 1 (PGAM1) Promotes Pancreatic Ductal Adenocarcinoma (PDAC) Metastasis by Acting as a Novel Downstream Target of the PI3K/Akt/mTOR Pathway.
Liu X, Tan X, Liu P, Wu Y, Qian S, Zhang X
Oncology research 2018 Aug 23;26(7):1123-1131
Oncology research 2018 Aug 23;26(7):1123-1131
Hypoxic Tumor-Derived Exosomal miR-301a Mediates M2 Macrophage Polarization via PTEN/PI3Kγ to Promote Pancreatic Cancer Metastasis.
Wang X, Luo G, Zhang K, Cao J, Huang C, Jiang T, Liu B, Su L, Qiu Z
Cancer research 2018 Aug 15;78(16):4586-4598
Cancer research 2018 Aug 15;78(16):4586-4598
LncRNA PTAR promotes EMT and invasion-metastasis in serous ovarian cancer by competitively binding miR-101-3p to regulate ZEB1 expression.
Liang H, Yu T, Han Y, Jiang H, Wang C, You T, Zhao X, Shan H, Yang R, Yang L, Shan H, Gu Y
Molecular cancer 2018 Aug 11;17(1):119
Molecular cancer 2018 Aug 11;17(1):119
Ezrin/NF-κB Pathway Regulates EGF-induced Epithelial-Mesenchymal Transition (EMT), Metastasis, and Progression of Osteosarcoma.
Liu P, Yang P, Zhang Z, Liu M, Hu S
Medical science monitor : international medical journal of experimental and clinical research 2018 Apr 9;24:2098-2108
Medical science monitor : international medical journal of experimental and clinical research 2018 Apr 9;24:2098-2108
GRHL2 suppresses tumor metastasis via regulation of transcriptional activity of RhoG in non-small cell lung cancer.
Pan X, Zhang R, Xie C, Gan M, Yao S, Yao Y, Jin J, Han T, Huang Y, Gong Y, Wang J, Yu B
American journal of translational research 2017;9(9):4217-4226
American journal of translational research 2017;9(9):4217-4226
Elevated expression of Derlin-1 associates with unfavorable survival time of squamous cell carcinoma of the head and neck and promotes its malignance.
Pi L, Zhu G, She L, Wei M, Liu G, Chen C, Hu D, Peng F, Tan H, Liu Y, Huang D, Tian Y, Zhang X
Journal of Cancer 2017;8(12):2336-2345
Journal of Cancer 2017;8(12):2336-2345
Fentanyl Promotes Breast Cancer Cell Stemness and Epithelial-Mesenchymal Transition by Upregulating α1, 6-Fucosylation via Wnt/β-Catenin Signaling Pathway.
Yang HF, Yu M, Jin HD, Yao JQ, Lu ZL, Yabasin IB, Yan Q, Wen QP
Frontiers in physiology 2017;8:510
Frontiers in physiology 2017;8:510
MiR-200c Inhibits the Tumor Progression of Glioma via Targeting Moesin.
Qin Y, Chen W, Liu B, Zhou L, Deng L, Niu W, Bao D, Cheng C, Li D, Liu S, Niu C
Theranostics 2017;7(6):1663-1673
Theranostics 2017;7(6):1663-1673
Material-induced Senescence (MIS): Fluidity Induces Senescent Type Cell Death of Lung Cancer Cells via Insulin-Like Growth Factor Binding Protein 5.
Mano SS, Uto K, Ebara M
Theranostics 2017;7(19):4658-4670
Theranostics 2017;7(19):4658-4670
MiR-98 inhibits malignant progression via targeting MTDH in squamous cell carcinoma of the head and neck.
Tan H, Zhu G, She L, Wei M, Wang Y, Pi L, Chen C, Zhang D, Tan P, Chen J, Huang D, Tian Y, Liu Y, Zhang X
American journal of cancer research 2017;7(12):2554-2565
American journal of cancer research 2017;7(12):2554-2565
β-Catenin Cooperates with CREB Binding Protein to Promote the Growth of Tumor Cells.
Yu W, Li L, Zheng F, Yang W, Zhao S, Tian C, Yin W, Chen Y, Guo W, Zou L, Deng W
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(2):467-478
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;44(2):467-478
Anti-OSM Antibody Inhibits Tubulointerstitial Lesion in a Murine Model of Lupus Nephritis.
Liu Q, Du Y, Li K, Zhang W, Feng X, Hao J, Li H, Liu S
Mediators of inflammation 2017;2017:3038514
Mediators of inflammation 2017;2017:3038514
Clopidogrel in a combined therapy with anticancer drugs-effect on tumor growth, metastasis, and treatment toxicity: Studies in animal models.
Denslow A, Świtalska M, Jarosz J, Papiernik D, Porshneva K, Nowak M, Wietrzyk J
PloS one 2017;12(12):e0188740
PloS one 2017;12(12):e0188740
MiR-211 inhibits cell epithelial-mesenchymal transition by targeting MMP9 in gastric cancer.
Wang XD, Wen FX, Liu BC, Song Y
International journal of clinical and experimental pathology 2017;10(7):7551-7558
International journal of clinical and experimental pathology 2017;10(7):7551-7558
Novel role of granulocyte-macrophage colony-stimulating factor: antitumor effects through inhibition of epithelial-to-mesenchymal transition in esophageal cancer.
Zhang J, Liu Q, Qiao L, Hu P, Deng G, Liang N, Xie J, Luo H, Zhang J
OncoTargets and therapy 2017;10:2227-2237
OncoTargets and therapy 2017;10:2227-2237
TBL1XR1 predicts isolated tumor cells and micrometastasis in patients with TNM stage I/II colorectal cancer.
Liu H, Liu Z, Li K, Li S, Song L, Gong Z, Shi W, Yang H, Xu Y, Ning S, Ismail S, Chen Y
Journal of gastroenterology and hepatology 2017 Sep;32(9):1570-1580
Journal of gastroenterology and hepatology 2017 Sep;32(9):1570-1580
Elucidating Mechanisms of Bladder Repair after Hyaluronan Instillation in Ketamine-Induced Ulcerative Cystitis in Animal Model.
Lee YL, Lin KL, Chuang SM, Lee YC, Lu MC, Wu BN, Wu WJ, Yuan SF, Ho WT, Juan YS
The American journal of pathology 2017 Sep;187(9):1945-1959
The American journal of pathology 2017 Sep;187(9):1945-1959
Long non-coding RNA NEAT1 regulates epithelial membrane protein 2 expression to repress nasopharyngeal carcinoma migration and irradiation-resistance through miR-101-3p as a competing endogenous RNA mechanism.
Wang Y, Wang C, Chen C, Wu F, Shen P, Zhang P, He G, Li X
Oncotarget 2017 Sep 19;8(41):70156-70171
Oncotarget 2017 Sep 19;8(41):70156-70171
Overexpression of RCC2 Enhances Cell Motility and Promotes Tumor Metastasis in Lung Adenocarcinoma by Inducing Epithelial-Mesenchymal Transition.
Pang B, Wu N, Guan R, Pang L, Li X, Li S, Tang L, Guo Y, Chen J, Sun D, Sun H, Dai J, Bai J, Ji G, Liu P, Liu A, Wang Q, Xiao S, Fu S, Jin Y
Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Sep 15;23(18):5598-5610
Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Sep 15;23(18):5598-5610
In vitro anticancer activities of osthole against renal cell carcinoma cells.
Liu L, Mao J, Wang Q, Zhang Z, Wu G, Tang Q, Zhao B, Li L, Li Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:1020-1027
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:1020-1027
Alterted SLIT2/ROBO1 signalling is linked to impaired placentation of missed and threatened miscarriage in early pregnancy.
Li P, Shi Y, Shuai H, Cai Y, Lu W, Wang G, Gao L, Wang L, Fan X, Yang X
Histopathology 2017 Oct;71(4):543-552
Histopathology 2017 Oct;71(4):543-552
E‑cadherin involvement in human lens epithelial cell transdifferentiation may be associated with N‑cadherin.
Huang L, Jiang J, Guo Q, Yang H
Molecular medicine reports 2017 Oct;16(4):5031-5035
Molecular medicine reports 2017 Oct;16(4):5031-5035
Macrophage migration inhibitory factor promotes vasculogenic mimicry formation induced by hypoxia via CXCR4/AKT/EMT pathway in human glioblastoma cells.
Guo X, Xu S, Gao X, Wang J, Xue H, Chen Z, Zhang J, Guo X, Qian M, Qiu W, Li G
Oncotarget 2017 Oct 6;8(46):80358-80372
Oncotarget 2017 Oct 6;8(46):80358-80372
LncRNAAC132217.4, a KLF8-regulated long non-coding RNA, facilitates oral squamous cell carcinoma metastasis by upregulating IGF2 expression.
Li X, Ma C, Zhang L, Li N, Zhang X, He J, He R, Shao M, Wang J, Kang L, Han C
Cancer letters 2017 Oct 28;407:45-56
Cancer letters 2017 Oct 28;407:45-56
β-defensin 1 expression in HCV infected liver/liver cancer: an important role in protecting HCV progression and liver cancer development.
Ling YM, Chen JY, Guo L, Wang CY, Tan WT, Wen Q, Zhang SD, Deng GH, Lin Y, Kwok HF
Scientific reports 2017 Oct 17;7(1):13404
Scientific reports 2017 Oct 17;7(1):13404
MicroRNA-23a promotes pancreatic cancer metastasis by targeting epithelial splicing regulator protein 1.
Wu G, Li Z, Jiang P, Zhang X, Xu Y, Chen K, Li X
Oncotarget 2017 Oct 10;8(47):82854-82871
Oncotarget 2017 Oct 10;8(47):82854-82871
Single factors alone can induce mesenchymal-like morphology, but not promote full EMT in breast cancer cell lines with different hormone statuses.
Tveitarås MK, Reigstad I, Leiss L, Reed RK, Stuhr L
Experimental cell research 2017 Oct 1;359(1):257-265
Experimental cell research 2017 Oct 1;359(1):257-265
Administration of alpha-ketoglutarate improves epithelial restitution under stress injury in early-weaning piglets.
He L, Zhou X, Huang N, Li H, Cui Z, Tian J, Jiang Q, Liu S, Wu J, Li T, Yao K, Yin Y
Oncotarget 2017 Nov 3;8(54):91965-91978
Oncotarget 2017 Nov 3;8(54):91965-91978
Extracts of Zuo Jin Wan, a traditional Chinese medicine, phenocopies 5-HTR1D antagonist in attenuating Wnt/β-catenin signaling in colorectal cancer cells.
Pan J, Xu Y, Song H, Zhou X, Yao Z, Ji G
BMC complementary and alternative medicine 2017 Nov 28;17(1):506
BMC complementary and alternative medicine 2017 Nov 28;17(1):506
Protein tyrosine phosphatase receptor-type δ acts as a negative regulator suppressing breast cancer.
Yu X, Zhang F, Mao J, Lu Y, Li J, Ma W, Fan S, Zhang C, Li Q, Wang B, Song B, Li L
Oncotarget 2017 Nov 17;8(58):98798-98811
Oncotarget 2017 Nov 17;8(58):98798-98811
The mechanism of epithelial-mesenchymal transition induced by TGF-β1 in neuroblastoma cells.
Shao JB, Gao ZM, Huang WY, Lu ZB
International journal of oncology 2017 May;50(5):1623-1633
International journal of oncology 2017 May;50(5):1623-1633
Downregulation of miR-218 contributes to epithelial-mesenchymal transition and tumor metastasis in lung cancer by targeting Slug/ZEB2 signaling.
Shi ZM, Wang L, Shen H, Jiang CF, Ge X, Li DM, Wen YY, Sun HR, Pan MH, Li W, Shu YQ, Liu LZ, Peiper SC, He J, Jiang BH
Oncogene 2017 May 4;36(18):2577-2588
Oncogene 2017 May 4;36(18):2577-2588
Calmodulin promotes matrix metalloproteinase 9 production and cell migration by inhibiting the ubiquitination and degradation of TBC1D3 oncoprotein in human breast cancer cells.
Zhao H, Zhang L, Zhang Y, Zhao L, Wan Q, Wang B, Bu X, Wan M, Shen C
Oncotarget 2017 May 30;8(22):36383-36398
Oncotarget 2017 May 30;8(22):36383-36398
NID1, a new regulator of EMT required for metastasis and chemoresistance of ovarian cancer cells.
Zhou Y, Zhu Y, Fan X, Zhang C, Wang Y, Zhang L, Zhang H, Wen T, Zhang K, Huo X, Jiang X, Bu Y, Zhang Y
Oncotarget 2017 May 16;8(20):33110-33121
Oncotarget 2017 May 16;8(20):33110-33121
APC(Cdh1) controls cell cycle entry during liver regeneration.
Cheng R, Liang X, Zhao Q, Lian Z, Tang L, Qiu C, Chen H, Zhang P
Experimental cell research 2017 May 15;354(2):78-84
Experimental cell research 2017 May 15;354(2):78-84
Down-regulation of KIAA1199/CEMIP by miR-216a suppresses tumor invasion and metastasis in colorectal cancer.
Zhang D, Zhao L, Shen Q, Lv Q, Jin M, Ma H, Nie X, Zheng X, Huang S, Zhou P, Wu G, Zhang T
International journal of cancer 2017 May 15;140(10):2298-2309
International journal of cancer 2017 May 15;140(10):2298-2309
Osthole inhibits the tumorigenesis of hepatocellular carcinoma cells.
Lin ZK, Liu J, Jiang GQ, Tan G, Gong P, Luo HF, Li HM, Du J, Ning Z, Xin Y, Wang ZY
Oncology reports 2017 Mar;37(3):1611-1618
Oncology reports 2017 Mar;37(3):1611-1618
The effects of 1,4-dimethylpyridine in metastatic prostate cancer in mice.
Denslow A, Switalska M, Nowak M, Maciejewska M, Chlopicki S, Marcinek A, Gebicki J, Wietrzyk J
BMC cancer 2017 Mar 7;17(1):177
BMC cancer 2017 Mar 7;17(1):177
Transducin (β)-like 1 X-linked receptor 1 promotes gastric cancer progression via the ERK1/2 pathway.
Zhou Q, Wang X, Yu Z, Wu X, Chen X, Li J, Zhu Z, Liu B, Su L
Oncogene 2017 Mar 30;36(13):1873-1886
Oncogene 2017 Mar 30;36(13):1873-1886
IL-6 secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathway.
Wu X, Tao P, Zhou Q, Li J, Yu Z, Wang X, Li J, Li C, Yan M, Zhu Z, Liu B, Su L
Oncotarget 2017 Mar 28;8(13):20741-20750
Oncotarget 2017 Mar 28;8(13):20741-20750
Correlations between TBL1XR1 and recurrence of colorectal cancer.
Liu H, Xu Y, Zhang Q, Li K, Wang D, Li S, Ning S, Yang H, Shi W, Liu Z, Chen Y
Scientific reports 2017 Mar 15;7:44275
Scientific reports 2017 Mar 15;7:44275
NUBPL, a novel metastasis-related gene, promotes colorectal carcinoma cell motility by inducing epithelial-mesenchymal transition.
Wang Y, Wu N, Sun D, Sun H, Tong D, Liu D, Pang B, Li S, Wei J, Dai J, Liu Y, Bai J, Geng J, Fu S, Jin Y
Cancer science 2017 Jun;108(6):1169-1176
Cancer science 2017 Jun;108(6):1169-1176
Hypoxia-induced PLOD2 promotes proliferation, migration and invasion via PI3K/Akt signaling in glioma.
Song Y, Zheng S, Wang J, Long H, Fang L, Wang G, Li Z, Que T, Liu Y, Li Y, Zhang X, Fang W, Qi S
Oncotarget 2017 Jun 27;8(26):41947-41962
Oncotarget 2017 Jun 27;8(26):41947-41962
Curcumin increases efficiency of γ-irradiation in gliomas by inhibiting Hedgehog signaling pathway.
Meng X, Cai J, Liu J, Han B, Gao F, Gao W, Zhang Y, Zhang J, Zhao Z, Jiang C
Cell cycle (Georgetown, Tex.) 2017 Jun 18;16(12):1181-1192
Cell cycle (Georgetown, Tex.) 2017 Jun 18;16(12):1181-1192
STIM1 and STIM2 differently regulate endogenous Ca(2+) entry and promote TGF-β-induced EMT in breast cancer cells.
Zhang S, Miao Y, Zheng X, Gong Y, Zhang J, Zou F, Cai C
Biochemical and biophysical research communications 2017 Jun 17;488(1):74-80
Biochemical and biophysical research communications 2017 Jun 17;488(1):74-80
MTA1 promotes epithelial to mesenchymal transition and metastasis in non-small-cell lung cancer.
Ma K, Fan Y, Dong X, Dong D, Guo Y, Wei X, Ning J, Geng Q, Wang C, Hu Y, Li M, Niu W, Li E, Wu Y
Oncotarget 2017 Jun 13;8(24):38825-38840
Oncotarget 2017 Jun 13;8(24):38825-38840
Qi-Zhu-Xie-Zhuo-Fang reduces serum uric acid levels and ameliorates renal fibrosis in hyperuricemic nephropathy rats.
Huijuan W, Xiaoxu C, Rui S, Xinghui L, Beibei T, Jianchun M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jul;91:358-365
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jul;91:358-365
Self-renewing Monolayer of Primary Colonic or Rectal Epithelial Cells.
Wang Y, DiSalvo M, Gunasekara DB, Dutton J, Proctor A, Lebhar MS, Williamson IA, Speer J, Howard RL, Smiddy NM, Bultman SJ, Sims CE, Magness ST, Allbritton NL
Cellular and molecular gastroenterology and hepatology 2017 Jul;4(1):165-182.e7
Cellular and molecular gastroenterology and hepatology 2017 Jul;4(1):165-182.e7
Transforming growth factor-β1 contributes to oxaliplatin resistance in colorectal cancer via epithelial to mesenchymal transition.
Mao L, Li Y, Zhao J, Li Q, Yang B, Wang Y, Zhu Z, Sun H, Zhai Z
Oncology letters 2017 Jul;14(1):647-654
Oncology letters 2017 Jul;14(1):647-654
Long non-coding RNA UCA1 promotes gallbladder cancer progression by epigenetically repressing p21 and E-cadherin expression.
Cai Q, Jin L, Wang S, Zhou D, Wang J, Tang Z, Quan Z
Oncotarget 2017 Jul 18;8(29):47957-47968
Oncotarget 2017 Jul 18;8(29):47957-47968
Linc-DYNC2H1-4 promotes EMT and CSC phenotypes by acting as a sponge of miR-145 in pancreatic cancer cells.
Gao Y, Zhang Z, Li K, Gong L, Yang Q, Huang X, Hong C, Ding M, Yang H
Cell death & disease 2017 Jul 13;8(7):e2924
Cell death & disease 2017 Jul 13;8(7):e2924
Autophagy plays a role in FSTL1-induced epithelial mesenchymal transition and airway remodeling in asthma.
Liu T, Liu Y, Miller M, Cao L, Zhao J, Wu J, Wang J, Liu L, Li S, Zou M, Xu J, Broide DH, Dong L
American journal of physiology. Lung cellular and molecular physiology 2017 Jul 1;313(1):L27-L40
American journal of physiology. Lung cellular and molecular physiology 2017 Jul 1;313(1):L27-L40
Downregulation of Bmi-1 suppresses epithelial‑mesenchymal transition in melanoma.
Liu Y, Chu Z, Li Q, Peng B, Xu S, Lian CG, Geng S
Oncology reports 2017 Jan;37(1):139-146
Oncology reports 2017 Jan;37(1):139-146
CAPZA1 modulates EMT by regulating actin cytoskeleton remodelling in hepatocellular carcinoma.
Huang D, Cao L, Zheng S
Journal of experimental & clinical cancer research : CR 2017 Jan 16;36(1):13
Journal of experimental & clinical cancer research : CR 2017 Jan 16;36(1):13
High-mobility group box 1 is overexpressed in cervical carcinoma and promotes cell invasion and migration in vitro.
Pang X, Zhang Y, Zhang S
Oncology reports 2017 Feb;37(2):831-840
Oncology reports 2017 Feb;37(2):831-840
Epithelial-to-Mesenchymal Transition in Paclitaxel-Resistant Ovarian Cancer Cells Is Downregulated by Luteolin.
Dia VP, Pangloli P
Journal of cellular physiology 2017 Feb;232(2):391-401
Journal of cellular physiology 2017 Feb;232(2):391-401
Long non-coding RNA AK058003, as a precursor of miR-15a, interacts with HuR to inhibit the expression of γ-synuclein in hepatocellular carcinoma cells.
He X, Zheng Y, Zhang Y, Gan Y, Zhou Y, Liang H, Wu D, Ge W, Deng J, Xu X
Oncotarget 2017 Feb 7;8(6):9451-9465
Oncotarget 2017 Feb 7;8(6):9451-9465
Sinomenine hydrochloride attenuates the proliferation, migration, invasiveness, angiogenesis and epithelial-mesenchymal transition of clear-cell renal cell carcinoma cells via targeting Smad in vitro.
Zhao B, Liu L, Mao J, Liu K, Fan W, Liu J, Zhang Z, Li Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Dec;96:1036-1044
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Dec;96:1036-1044
miR-200b-containing microvesicles attenuate experimental colitis associated intestinal fibrosis by inhibiting epithelial-mesenchymal transition.
Yang J, Zhou CZ, Zhu R, Fan H, Liu XX, Duan XY, Tang Q, Shou ZX, Zuo DM
Journal of gastroenterology and hepatology 2017 Dec;32(12):1966-1974
Journal of gastroenterology and hepatology 2017 Dec;32(12):1966-1974
Inversed Expression Patterns of S100A4 and E-Cadherin in Cervical Cancers: Implication in Epithelial-Mesenchymal Transition.
Liu M, Liu J, Yang B, Gao X, Gao LL, Kong QY, Zhang P, Li H
Anatomical record (Hoboken, N.J. : 2007) 2017 Dec;300(12):2184-2191
Anatomical record (Hoboken, N.J. : 2007) 2017 Dec;300(12):2184-2191
Interaction network of coexpressed mRNA, miRNA, and lncRNA activated by TGF‑β1 regulates EMT in human pulmonary epithelial cell.
Liu H, Zhao X, Xiang J, Zhang J, Meng C, Zhang J, Li M, Song X, Lv C
Molecular medicine reports 2017 Dec;16(6):8045-8054
Molecular medicine reports 2017 Dec;16(6):8045-8054
Mastl overexpression is associated with epithelial to mesenchymal transition and predicts a poor clinical outcome in gastric cancer.
Sun XJ, Li YL, Wang LG, Liu LQ, Ma H, Hou WH, Yu JM
Oncology letters 2017 Dec;14(6):7283-7287
Oncology letters 2017 Dec;14(6):7283-7287
Disruption of the c-Myc/miR-200b-3p/PRDX2 regulatory loop enhances tumor metastasis and chemotherapeutic resistance in colorectal cancer.
Lv Z, Wei J, You W, Wang R, Shang J, Xiong Y, Yang H, Yang X, Fu Z
Journal of translational medicine 2017 Dec 19;15(1):257
Journal of translational medicine 2017 Dec 19;15(1):257
Ethanol extract of gardenia fruit alleviates renal interstitial fibrosis induced by unilateral ureteral obstruction in rats.
Li X, Ma M, Zhang X, Deng L, Wang Y, Bian Z, Cai S, Peng B, Yang J, Chen Y
Experimental and therapeutic medicine 2017 Aug;14(2):1381-1388
Experimental and therapeutic medicine 2017 Aug;14(2):1381-1388
SLC39A4 expression is associated with enhanced cell migration, cisplatin resistance, and poor survival in non-small cell lung cancer.
Wu DM, Liu T, Deng SH, Han R, Xu Y
Scientific reports 2017 Aug 3;7(1):7211
Scientific reports 2017 Aug 3;7(1):7211
Metformin reverses prostate cancer resistance to enzalutamide by targeting TGF-β1/STAT3 axis-regulated EMT.
Liu Q, Tong D, Liu G, Xu J, Do K, Geary K, Zhang D, Zhang J, Zhang Y, Li Y, Bi G, Lan W, Jiang J
Cell death & disease 2017 Aug 24;8(8):e3007
Cell death & disease 2017 Aug 24;8(8):e3007
β-elemene inhibits tumor-promoting effect of M2 macrophages in lung cancer.
Yu X, Xu M, Li N, Li Z, Li H, Shao S, Zou K, Zou L
Biochemical and biophysical research communications 2017 Aug 19;490(2):514-520
Biochemical and biophysical research communications 2017 Aug 19;490(2):514-520
IL-6 promotes epithelial-to-mesenchymal transition of human peritoneal mesothelial cells possibly through the JAK2/STAT3 signaling pathway.
Xiao J, Gong Y, Chen Y, Yu D, Wang X, Zhang X, Dou Y, Liu D, Cheng G, Lu S, Yuan W, Li Y, Zhao Z
American journal of physiology. Renal physiology 2017 Aug 1;313(2):F310-F318
American journal of physiology. Renal physiology 2017 Aug 1;313(2):F310-F318
Atrial natriuretic peptide: A novel mediator for TGF-β1-induced epithelial-mesenchymal transition in 16HBE-14o and A549 cells.
Chu S, Zhang X, Sun Y, Yu Y, Liang Y, Jiang M, Huang J, Ma L
Peptides 2017 Apr;90:1-9
Peptides 2017 Apr;90:1-9
Long non-coding RNA TUG1 promotes cell proliferation and metastasis by negatively regulating miR-300 in gallbladder carcinoma.
Ma F, Wang SH, Cai Q, Jin LY, Zhou D, Ding J, Quan ZW
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Apr;88:863-869
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Apr;88:863-869
The role of metastasis-associated in colon cancer 1 (MACC1) in endometrial carcinoma tumorigenesis and progression.
Chen S, Zong ZH, Wu DD, Sun KX, Liu BL, Zhao Y
Molecular carcinogenesis 2017 Apr;56(4):1361-1371
Molecular carcinogenesis 2017 Apr;56(4):1361-1371
Adipose-derived mesenchymal stem cells promote osteosarcoma proliferation and metastasis by activating the STAT3 pathway.
Wang Y, Chu Y, Yue B, Ma X, Zhang G, Xiang H, Liu Y, Wang T, Wu X, Chen B
Oncotarget 2017 Apr 4;8(14):23803-23816
Oncotarget 2017 Apr 4;8(14):23803-23816
Mammalian Eps15 homology domain 1 promotes metastasis in non-small cell lung cancer by inducing epithelial-mesenchymal transition.
Meng Q, Xing Y, Ren T, Lu H, Xi Y, Jiang Z, Hu J, Li C, Sun L, Sun D, Cai L
Oncotarget 2017 Apr 4;8(14):22433-22442
Oncotarget 2017 Apr 4;8(14):22433-22442
microRNA-802 inhibits epithelial-mesenchymal transition through targeting flotillin-2 in human prostate cancer.
Wang D, Lu G, Shao Y, Xu D
Bioscience reports 2017 Apr 30;37(2)
Bioscience reports 2017 Apr 30;37(2)
Gas6/Axl Axis Contributes to Chemoresistance and Metastasis in Breast Cancer through Akt/GSK-3β/β-catenin Signaling.
Wang C, Jin H, Wang N, Fan S, Wang Y, Zhang Y, Wei L, Tao X, Gu D, Zhao F, Fang J, Yao M, Qin W
Theranostics 2016;6(8):1205-19
Theranostics 2016;6(8):1205-19
Radiation promotes epithelial-to-mesenchymal transition and invasion of pancreatic cancer cell by activating carcinoma-associated fibroblasts.
Li D, Qu C, Ning Z, Wang H, Zang K, Zhuang L, Chen L, Wang P, Meng Z
American journal of cancer research 2016;6(10):2192-2206
American journal of cancer research 2016;6(10):2192-2206
Elevated eukaryotic elongation factor 2 expression is involved in proliferation and invasion of lung squamous cell carcinoma.
Song Y, Sun B, Hao L, Hu J, Du S, Zhou X, Zhang L, Liu L, Gong L, Chi X, Liu Q, Shao S
Oncotarget 2016 Sep 6;7(36):58470-58482
Oncotarget 2016 Sep 6;7(36):58470-58482
Oral kanglaite injection (KLTI) attenuates the lung cancer-promoting effect of high-fat diet (HFD)-induced obesity.
Cao N, Ma X, Guo Z, Zheng Y, Geng S, Meng M, Du Z, Lin H, Duan Y, Du G
Oncotarget 2016 Sep 20;7(38):61093-61106
Oncotarget 2016 Sep 20;7(38):61093-61106
MMP-14 and CD44 in Epithelial-to-Mesenchymal Transition (EMT) in ovarian cancer.
Vos MC, Hollemans E, Ezendam N, Feijen H, Boll D, Pijlman B, van der Putten H, Klinkhamer P, van Kuppevelt TH, van der Wurff AA, Massuger LF
Journal of ovarian research 2016 Sep 2;9(1):53
Journal of ovarian research 2016 Sep 2;9(1):53
Effects of RECQ1 helicase silencing on non-small cell lung cancer cells.
Li L, Gao M, Song B, Zhang H, Wang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Oct;83:1227-1232
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Oct;83:1227-1232
Depletion of Dicer promotes epithelial ovarian cancer progression by elevating PDIA3 expression.
Zhu Y, Cai L, Guo J, Chen N, Yi X, Zhao Y, Cai J, Wang Z
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Oct;37(10):14009-14023
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Oct;37(10):14009-14023
MicroRNA-106a regulates phosphatase and tensin homologue expression and promotes the proliferation and invasion of ovarian cancer cells.
Chen L, Zhang F, Sheng XG, Zhang SQ, Chen YT, Liu BW
Oncology reports 2016 Oct;36(4):2135-41
Oncology reports 2016 Oct;36(4):2135-41
Design and Construction of a Multi-Organ Microfluidic Chip Mimicking the in vivo Microenvironment of Lung Cancer Metastasis.
Xu Z, Li E, Guo Z, Yu R, Hao H, Xu Y, Sun Z, Li X, Lyu J, Wang Q
ACS applied materials & interfaces 2016 Oct 5;8(39):25840-25847
ACS applied materials & interfaces 2016 Oct 5;8(39):25840-25847
Hsp60 exerts a tumor suppressor function by inducing cell differentiation and inhibiting invasion in hepatocellular carcinoma.
Zhang J, Zhou X, Chang H, Huang X, Guo X, Du X, Tian S, Wang L, Lyv Y, Yuan P, Xing J
Oncotarget 2016 Oct 18;7(42):68976-68989
Oncotarget 2016 Oct 18;7(42):68976-68989
Effect of PPM1H on malignant phenotype of human pancreatic cancer cells.
Zhu H, Qin H, Li DM, Liu J, Zhao Q
Oncology reports 2016 Nov;36(5):2926-2934
Oncology reports 2016 Nov;36(5):2926-2934
Tanshinone IIA attenuates epithelial-mesenchymal transition to inhibit the tracheal narrowing.
Duan H, Ma L, Liu H, Zhang Y, Zhang Z, Yan X, Li X
The Journal of surgical research 2016 Nov;206(1):252-262
The Journal of surgical research 2016 Nov;206(1):252-262
miR-200c regulates crizotinib-resistant ALK-positive lung cancer cells by reversing epithelial-mesenchymal transition via targeting ZEB1.
Gao HX, Yan L, Li C, Zhao LM, Liu W
Molecular medicine reports 2016 Nov;14(5):4135-4143
Molecular medicine reports 2016 Nov;14(5):4135-4143
E-cadherin is important for cell differentiation during osteoclastogenesis.
Fiorino C, Harrison RE
Bone 2016 May;86:106-18
Bone 2016 May;86:106-18
PTEN Regulates Renal Extracellular Matrix Deposit via Increased CTGF in Diabetes Mellitus.
Zhu L, Zhao S, Liu S, Liu Q, Li F, Hao J
Journal of cellular biochemistry 2016 May;117(5):1187-98
Journal of cellular biochemistry 2016 May;117(5):1187-98
miR-542-3p suppresses invasion and metastasis by targeting the proto-oncogene serine/threonine protein kinase, PIM1, in melanoma.
Rang Z, Yang G, Wang YW, Cui F
Biochemical and biophysical research communications 2016 May 27;474(2):315-320
Biochemical and biophysical research communications 2016 May 27;474(2):315-320
Neddylation controls basal MKK7 kinase activity in breast cancer cells.
Zhu T, Wang J, Pei Y, Wang Q, Wu Y, Qiu G, Zhang D, Lv M, Li W, Zhang J
Oncogene 2016 May 19;35(20):2624-33
Oncogene 2016 May 19;35(20):2624-33
The SDF-1/CXCR4 chemokine axis in uveal melanoma cell proliferation and migration.
Bi J, Li P, Li C, He J, Wang Y, Zhang H, Fan X, Jia R, Ge S
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Mar;37(3):4175-82
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Mar;37(3):4175-82
β-Carotene Induces Apoptosis in Human Esophageal Squamous Cell Carcinoma Cell Lines via the Cav-1/AKT/NF-κB Signaling Pathway.
Zhu X, Zhang Y, Li Q, Yang L, Zhang N, Ma S, Zhang K, Song J, Guan F
Journal of biochemical and molecular toxicology 2016 Mar;30(3):148-57
Journal of biochemical and molecular toxicology 2016 Mar;30(3):148-57
The anti-metastatic effect of 8-MOP on hepatocellular carcinoma is potentiated by the down-regulation of bHLH transcription factor DEC1.
Xiong J, Yang H, Luo W, Shan E, Liu J, Zhang F, Xi T, Yang J
Pharmacological research 2016 Mar;105:121-33
Pharmacological research 2016 Mar;105:121-33
IL-27 inhibits the TGF-β1-induced epithelial-mesenchymal transition in alveolar epithelial cells.
Dong Z, Tai W, Lei W, Wang Y, Li Z, Zhang T
BMC cell biology 2016 Mar 1;17:7
BMC cell biology 2016 Mar 1;17:7
Silencing stem cell factor attenuates stemness and inhibits migration of cancer stem cells derived from Lewis lung carcinoma cells.
Wang L, Wang J, Li Z, Liu Y, Jiang M, Li Y, Cao D, Zhao M, Wang F, Luo F
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jun;37(6):7213-27
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jun;37(6):7213-27
The E545K mutation of PIK3CA promotes gallbladder carcinoma progression through enhanced binding to EGFR.
Zhao S, Cao Y, Liu SB, Wang XA, Bao RF, Shu YJ, Hu YP, Zhang YJ, Jiang L, Zhang F, Liang HB, Li HF, Ma Q, Xu Y, Wang Z, Zhang YC, Chen L, Zhou J, Liu YB
Journal of experimental & clinical cancer research : CR 2016 Jun 18;35(1):97
Journal of experimental & clinical cancer research : CR 2016 Jun 18;35(1):97
microRNA-374a suppresses colon cancer progression by directly reducing CCND1 to inactivate the PI3K/AKT pathway.
Chen Y, Jiang J, Zhao M, Luo X, Liang Z, Zhen Y, Fu Q, Deng X, Lin X, Li L, Luo R, Liu Z, Fang W
Oncotarget 2016 Jul 5;7(27):41306-41319
Oncotarget 2016 Jul 5;7(27):41306-41319
Conditional ablation of TGF-β signaling inhibits tumor progression and invasion in an induced mouse bladder cancer model.
Liang Y, Zhu F, Zhang H, Chen D, Zhang X, Gao Q, Li Y
Scientific reports 2016 Jul 5;6:29479
Scientific reports 2016 Jul 5;6:29479
Effect of astragalus injection on renal tubular epithelial transdifferentiation in type 2 diabetic mice.
Yi YE, Li SY, Nie YN, Jia DX, Zhang ZH, Wang YF, Wang Q
BMC complementary and alternative medicine 2016 Jul 16;16:222
BMC complementary and alternative medicine 2016 Jul 16;16:222
1-methylnicotinamide and its structural analog 1,4-dimethylpyridine for the prevention of cancer metastasis.
Blazejczyk A, Switalska M, Chlopicki S, Marcinek A, Gebicki J, Nowak M, Nasulewicz-Goldeman A, Wietrzyk J
Journal of experimental & clinical cancer research : CR 2016 Jul 13;35(1):110
Journal of experimental & clinical cancer research : CR 2016 Jul 13;35(1):110
Ginsenoside Rg3 inhibits epithelial-mesenchymal transition (EMT) and invasion of lung cancer by down-regulating FUT4.
Tian L, Shen D, Li X, Shan X, Wang X, Yan Q, Liu J
Oncotarget 2016 Jan 12;7(2):1619-32
Oncotarget 2016 Jan 12;7(2):1619-32
Establishment of a highly metastatic buccal squamous cell carcinoma cell line from a Sprague-Dawley Rat.
Qin X, Yan M, Zhang J, Xu Q, Lv Z, Chen W
Archives of oral biology 2016 Feb;62:1-9
Archives of oral biology 2016 Feb;62:1-9
APC/C(CDC20) and APC/C play pivotal roles in the process of embryonic development in Artemia sinica.
Zhang M, Yao F, Luan H, Zhao W, Jing T, Zhang S, Hou L, Zou X
Scientific reports 2016 Dec 19;6:39047
Scientific reports 2016 Dec 19;6:39047
Disrupting MALAT1/miR-200c sponge decreases invasion and migration in endometrioid endometrial carcinoma.
Li Q, Zhang C, Chen R, Xiong H, Qiu F, Liu S, Zhang M, Wang F, Wang Y, Zhou X, Xiao G, Wang X, Jiang Q
Cancer letters 2016 Dec 1;383(1):28-40
Cancer letters 2016 Dec 1;383(1):28-40
Regulation of CD40 signaling in colon cancer cells and its implications in clinical tissues.
Zhou Y, Zhou SX, Gao L, Li XA
Cancer immunology, immunotherapy : CII 2016 Aug;65(8):919-29
Cancer immunology, immunotherapy : CII 2016 Aug;65(8):919-29
Activation of the FAK/PI3K pathway is crucial for AURKA-induced epithelial-mesenchymal transition in laryngeal cancer.
Yang L, Zhou Q, Chen X, Su L, Liu B, Zhang H
Oncology reports 2016 Aug;36(2):819-26
Oncology reports 2016 Aug;36(2):819-26
High extracellular pressure promotes gastric cancer cell adhesion, invasion, migration and suppresses gastric cancer cell differentiation.
Su C, Zhang B, Liu W, Zheng H, Sun L, Tong J, Wang T, Jiang X, Liang H, Xue L, Zhang Q
Oncology reports 2016 Aug;36(2):1048-54
Oncology reports 2016 Aug;36(2):1048-54
Interplay between intergrin-linked kinase and ribonuclease inhibitor affects growth and metastasis of bladder cancer through signaling ILK pathways.
Zhuang X, Lv M, Zhong Z, Zhang L, Jiang R, Chen J
Journal of experimental & clinical cancer research : CR 2016 Aug 30;35(1):130
Journal of experimental & clinical cancer research : CR 2016 Aug 30;35(1):130
Gingerol Reverses the Cancer-Promoting Effect of Capsaicin by Increased TRPV1 Level in a Urethane-Induced Lung Carcinogenic Model.
Geng S, Zheng Y, Meng M, Guo Z, Cao N, Ma X, Du Z, Li J, Duan Y, Du G
Journal of agricultural and food chemistry 2016 Aug 10;64(31):6203-11
Journal of agricultural and food chemistry 2016 Aug 10;64(31):6203-11
DIXDC1 activates the Wnt signaling pathway and promotes gastric cancer cell invasion and metastasis.
Tan C, Qiao F, Wei P, Chi Y, Wang W, Ni S, Wang Q, Chen T, Sheng W, Du X, Wang L
Molecular carcinogenesis 2016 Apr;55(4):397-408
Molecular carcinogenesis 2016 Apr;55(4):397-408
Notch signaling induces epithelial-mesenchymal transition to promote invasion and metastasis in adenoid cystic carcinoma.
Zhao ZL, Ma SR, Wang WM, Huang CF, Yu GT, Wu TF, Bu LL, Wang YF, Zhao YF, Zhang WF, Sun ZJ
American journal of translational research 2015;7(1):162-74
American journal of translational research 2015;7(1):162-74
Overexpression of Long Non-Coding RNA ZXF2 Promotes Lung Adenocarcinoma Progression Through c-Myc Pathway.
Yang ZT, Li Z, Wang XG, Tan T, Yi F, Zhu H, Zhao JP, Zhou XF
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;35(6):2360-70
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;35(6):2360-70
FOXQ1 mediates the crosstalk between TGF-β and Wnt signaling pathways in the progression of colorectal cancer.
Peng X, Luo Z, Kang Q, Deng D, Wang Q, Peng H, Wang S, Wei Z
Cancer biology & therapy 2015;16(7):1099-109
Cancer biology & therapy 2015;16(7):1099-109
Cytoplasmic expression of pontin in renal cell carcinoma correlates with tumor invasion, metastasis and patients' survival.
Zhang X, Ren J, Yan L, Tang Y, Zhang W, Li D, Zang Y, Kong F, Xu Z
PloS one 2015;10(3):e0118659
PloS one 2015;10(3):e0118659
miR-195 Inhibits EMT by Targeting FGF2 in Prostate Cancer Cells.
Liu C, Guan H, Wang Y, Chen M, Xu B, Zhang L, Lu K, Tao T, Zhang X, Huang Y
PloS one 2015;10(12):e0144073
PloS one 2015;10(12):e0144073
Elevated GAPDH expression is associated with the proliferation and invasion of lung and esophageal squamous cell carcinomas.
Hao L, Zhou X, Liu S, Sun M, Song Y, Du S, Sun B, Guo C, Gong L, Hu J, Guan H, Shao S
Proteomics 2015 Sep;15(17):3087-100
Proteomics 2015 Sep;15(17):3087-100
Nuclear transcription factor CDX2 inhibits gastric cancer‑cell growth and reverses epithelial‑to‑mesenchymal transition in vitro and in vivo.
Zhang JF, Qu LS, Qian XF, Xia BL, Mao ZB, Chen WC
Molecular medicine reports 2015 Oct;12(4):5231-8
Molecular medicine reports 2015 Oct;12(4):5231-8
Pygopus-2 promotes invasion and metastasis of hepatic carcinoma cell by decreasing E-cadherin expression.
Zhang S, Li J, Liu P, Xu J, Zhao W, Xie C, Yin Z, Wang X
Oncotarget 2015 May 10;6(13):11074-86
Oncotarget 2015 May 10;6(13):11074-86
MG53-mediated cell membrane repair protects against acute kidney injury.
Duann P, Li H, Lin P, Tan T, Wang Z, Chen K, Zhou X, Gumpper K, Zhu H, Ludwig T, Mohler PJ, Rovin B, Abraham WT, Zeng C, Ma J
Science translational medicine 2015 Mar 18;7(279):279ra36
Science translational medicine 2015 Mar 18;7(279):279ra36
miR-494 suppresses the progression of breast cancer in vitro by targeting CXCR4 through the Wnt/β-catenin signaling pathway.
Song L, Liu D, Wang B, He J, Zhang S, Dai Z, Ma X, Wang X
Oncology reports 2015 Jul;34(1):525-31
Oncology reports 2015 Jul;34(1):525-31
Flotillin-2 promotes metastasis of nasopharyngeal carcinoma by activating NF-κB and PI3K/Akt3 signaling pathways.
Liu J, Huang W, Ren C, Wen Q, Liu W, Yang X, Wang L, Zhu B, Zeng L, Feng X, Zhang C, Chen H, Jia W, Zhang L, Xia X, Chen Y
Scientific reports 2015 Jul 24;5:11614
Scientific reports 2015 Jul 24;5:11614
Knockdown of glucose-regulated protein 78/binding immunoglobulin heavy chain protein expression by asymmetric small interfering RNA induces apoptosis in prostate cancer cells and attenuates migratory capability.
Lu T, Yang W, Wang Z, Hu Z, Zeng X, Yang C, Wang Y, Zhang Y, Li F, Liu Z, Wang D, Ye Z
Molecular medicine reports 2015 Jan;11(1):249-56
Molecular medicine reports 2015 Jan;11(1):249-56
The natural compound celastrol inhibits necroptosis and alleviates ulcerative colitis in mice.
Jia Z, Xu C, Shen J, Xia T, Yang J, He Y
International immunopharmacology 2015 Dec;29(2):552-559
International immunopharmacology 2015 Dec;29(2):552-559
Anti-pulmonary fibrotic activity of salvianolic acid B was screened by a novel method based on the cyto-biophysical properties.
Liu M, Zheng M, Xu H, Liu L, Li Y, Xiao W, Li J, Ma E
Biochemical and biophysical research communications 2015 Dec 4-11;468(1-2):214-20
Biochemical and biophysical research communications 2015 Dec 4-11;468(1-2):214-20
Truncating mutation in the autophagy gene UVRAG confers oncogenic properties and chemosensitivity in colorectal cancers.
He S, Zhao Z, Yang Y, O'Connell D, Zhang X, Oh S, Ma B, Lee JH, Zhang T, Varghese B, Yip J, Dolatshahi Pirooz S, Li M, Zhang Y, Li GM, Ellen Martin S, Machida K, Liang C
Nature communications 2015 Aug 3;6:7839
Nature communications 2015 Aug 3;6:7839
Ketamine-induced ulcerative cystitis and bladder apoptosis involve oxidative stress mediated by mitochondria and the endoplasmic reticulum.
Liu KM, Chuang SM, Long CY, Lee YL, Wang CC, Lu MC, Lin RJ, Lu JH, Jang MY, Wu WJ, Ho WT, Juan YS
American journal of physiology. Renal physiology 2015 Aug 15;309(4):F318-31
American journal of physiology. Renal physiology 2015 Aug 15;309(4):F318-31
DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway.
Huang W, Liu J, Feng X, Chen H, Zeng L, Huang G, Liu W, Wang L, Jia W, Chen J, Ren C
Medical oncology (Northwood, London, England) 2015 Apr;32(4):115
Medical oncology (Northwood, London, England) 2015 Apr;32(4):115
Aberrant expression of the autocrine motility factor receptor correlates with poor prognosis and promotes metastasis in gastric carcinoma.
Huang Z, Zhang N, Zha L, Mao HC, Chen X, Xiang JF, Zhang H, Wang ZW
Asian Pacific journal of cancer prevention : APJCP 2014;15(2):989-97
Asian Pacific journal of cancer prevention : APJCP 2014;15(2):989-97
BioPen: direct writing of functional materials at the point of care.
Han YL, Hu J, Genin GM, Lu TJ, Xu F
Scientific reports 2014 May 6;4:4872
Scientific reports 2014 May 6;4:4872
TGF-β2 induces transdifferentiation and fibrosis in human lens epithelial cells via regulating gremlin and CTGF.
Ma B, Kang Q, Qin L, Cui L, Pei C
Biochemical and biophysical research communications 2014 May 16;447(4):689-95
Biochemical and biophysical research communications 2014 May 16;447(4):689-95
Effects and mechanism of dehydroepiandrosterone on epithelial-mesenchymal transition in bronchial epithelial cells.
Xu L, Xiang X, Ji X, Wang W, Luo M, Luo S, Li K, Gong S, Liu S, Ma L, Chen P, Li J
Experimental lung research 2014 Jun;40(5):211-21
Experimental lung research 2014 Jun;40(5):211-21
Impact of Mucin1 knockdown on the phenotypic characteristics of the human hepatocellular carcinoma cell line SMMC-7721.
Li Q, Wang F, Liu G, Yuan H, Chen T, Wang J, Xie F, Zhai R, Wang F, Guo Y, Ni W, Tai G
Oncology reports 2014 Jun;31(6):2811-9
Oncology reports 2014 Jun;31(6):2811-9
Osteogenic differentiation of human amniotic epithelial cells and its application in alveolar defect restoration.
Jiawen S, Jianjun Z, Jiewen D, Dedong Y, Hongbo Y, Jun S, Xudong W, Shen SG, Lihe G
Stem cells translational medicine 2014 Dec;3(12):1504-13
Stem cells translational medicine 2014 Dec;3(12):1504-13
Increased expression levels of E-cadherin, cytokeratin 18 and 19 observed in preeclampsia were not correlated with disease severity.
Li XL, Dong X, Xue Y, Li CF, Gou WL, Chen Q
Placenta 2014 Aug;35(8):625-31
Placenta 2014 Aug;35(8):625-31
Vascular endothelial growth factor receptor-1 activation promotes migration and invasion of breast cancer cells through epithelial-mesenchymal transition.
Ning Q, Liu C, Hou L, Meng M, Zhang X, Luo M, Shao S, Zuo X, Zhao X
PloS one 2013;8(6):e65217
PloS one 2013;8(6):e65217
HMGA2 elicits EMT by activating the Wnt/β-catenin pathway in gastric cancer.
Zha L, Zhang J, Tang W, Zhang N, He M, Guo Y, Wang Z
Digestive diseases and sciences 2013 Mar;58(3):724-33
Digestive diseases and sciences 2013 Mar;58(3):724-33
Inhibition of cell migration by ouabain in the A549 human lung cancer cell line.
Liu N, Li Y, Su S, Wang N, Wang H, Li J
Oncology letters 2013 Aug;6(2):475-479
Oncology letters 2013 Aug;6(2):475-479
Tumor associated macrophage × cancer cell hybrids may acquire cancer stem cell properties in breast cancer.
Ding J, Jin W, Chen C, Shao Z, Wu J
PloS one 2012;7(7):e41942
PloS one 2012;7(7):e41942
Caveolin-1 knockdown is associated with the metastasis and proliferation of human lung cancer cell line NCI-H460.
Song Y, Xue L, Du S, Sun M, Hu J, Hao L, Gong L, Yeh D, Xiong H, Shao S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2012 Sep;66(6):439-47
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2012 Sep;66(6):439-47
Identification of human host proteins contributing to H5N1 influenza virus propagation by membrane proteomics.
Liu C, Zhang A, Guo J, Yang J, Zhou H, Chen H, Jin M
Journal of proteome research 2012 Nov 2;11(11):5396-405
Journal of proteome research 2012 Nov 2;11(11):5396-405
Response gene to complement-32 enhances metastatic phenotype by mediating transforming growth factor beta-induced epithelial-mesenchymal transition in human pancreatic cancer cell line BxPC-3.
Zhu L, Qin H, Li PY, Xu SN, Pang HF, Zhao HZ, Li DM, Zhao Q
Journal of experimental & clinical cancer research : CR 2012 Mar 29;31(1):29
Journal of experimental & clinical cancer research : CR 2012 Mar 29;31(1):29
Brain-selective kinase 2 (BRSK2) phosphorylation on PCTAIRE1 negatively regulates glucose-stimulated insulin secretion in pancreatic β-cells.
Chen XY, Gu XT, Saiyin H, Wan B, Zhang YJ, Li J, Wang YL, Gao R, Wang YF, Dong WP, Najjar SM, Zhang CY, Ding HF, Liu JO, Yu L
The Journal of biological chemistry 2012 Aug 31;287(36):30368-75
The Journal of biological chemistry 2012 Aug 31;287(36):30368-75
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse testis tissue were subjected to SDS PAGE followed by western blot with 20874-1-AP(E-cadherin antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-E-cadherin (IP:20874-1-AP, 3ug; Detection:20874-1-AP 1:1000) with A431 cells lysate 3000ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human skin using 20874-1-AP(E-cadherin antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human skin using 20874-1-AP(E-cadherin antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The E-cadherin antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human E-cadherin. This antibody recognizes human,mouse,rat antigen. The E-cadherin antibody has been validated for the following applications: ELISA, IHC, WB, IP, FC analysis.
