CDH1

gene product
CD324, UVO, uvomorulin
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]
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AntibodyRefsTypeAVIWBELICCIPIHCFC
GeneTex
30 antibodies
Novus Biologicals
300 antibodies
R&D Systems
36 antibodies
Invitrogen Antibodies
40 antibodies
Cell Signaling Technology, Inc
15 antibodies
Abnova Corporation
35 antibodies
NSJ Bioreagents
22 antibodies
Proteintech Group
3 antibodies
NovoPro Bioscience Inc.
13 antibodies
antibodies-online
398 antibodies