orb66765

antibody from Biorbyt

Targeting: CDH1 CD324, UVO, uvomorulin

Western blot (Data presented on provider website)

Antibody Data

Product number

orb66765

Provider

Biorbyt

Product name

CDH1 antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal to CDH1.Cadherin-1 (CDH1) is a single-pass membrane protein. Cadherins are calcium-dependent celladhesion proteins. They preferentially interact with themselves in a homophilic manner in connectingcells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved inmechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. It has a potentinvasive suppressor role. It is a ligand for integrin alpha-E/beta-7. Defects in CDH1 are the cause ofhereditary diffuse gastric cancer (HDGC) and are a cause of susceptibility to endometrial cancer(ENDMC) and ovarian cancer (OC).

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Vial size

100 ul

Storage

-20°C