60335-1-Ig

antibody from Proteintech Group

Targeting: CDH1 CD324, UVO, uvomorulin

Provider product page for 60335-1-Ig

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Product number: 60335-1-Ig - Provider product page
Provider: Proteintech Group
Product name: E-cadherin antibody
Antibody type: Monoclonal
Description: KD/KO validated E-cadherin antibody (Cat. #60335-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, pig, rat and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
Reactivity: Human, Rat, Porcine
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Antibody clone number: 6B11F11
Vial size: 20ul, 150ul

CDH1 protein structure - 60335-1-Ig shown in red.

Submitted references NLGN3 Upregulates Expression of ADAM10 to Promote the Cleavage of NLGN3 via Activating the LYN Pathway in Human Gliomas.

Dang NN, Li XB, Zhang M, Han C, Fan XY, Huang SH
Frontiers in cell and developmental biology 2021;9:662763

TAp63α Is Involved in Tobacco Smoke-Induced Lung Cancer EMT and the Anti-cancer Activity of Curcumin via miR-19 Transcriptional Suppression.

Xie C, Zhu J, Yang X, Huang C, Zhou L, Meng Z, Li X, Zhong C
Frontiers in cell and developmental biology 2021;9:645402

Extracellular Vesicles Carry lncRNA SNHG16 to Promote Metastasis of Breast Cancer Cells via the miR-892b/PPAPDC1A Axis.

Xia W, Liu Y, Cheng T, Xu T, Dong M, Hu X
Frontiers in cell and developmental biology 2021;9:628573

miR-942-5p Inhibits Proliferation, Metastasis, and Epithelial-Mesenchymal Transition in Colorectal Cancer by Targeting CCBE1.

Zhou L, Chen Q, Wu J, Yang J, Yin H, Tian J, Gong L, Kong D, Tao M
BioMed research international 2021;2021:9951405

BOP1 Used as a Novel Prognostic Marker and Correlated with Tumor Microenvironment in Pan-Cancer.

Li W, Song P, Zhao M, Gao L, Xie J, You C
Journal of oncology 2021;2021:3603030

Plakophilin-2 Promotes Lung Adenocarcinoma Development via Enhancing Focal Adhesion and Epithelial-Mesenchymal Transition.

Wu Y, Liu L, Shen X, Liu W, Ma R
Cancer management and research 2021;13:559-570

SCARA5 inhibits gastric cancer progression via epithelial-mesenchymal transition suppression.

Zhang H, Liu C, Wang X, Wang Y, Zheng J
Journal of Cancer 2021;12(8):2412-2421

Deltex3 inhibits Epithelial Mesenchymal Transition in Papillary Thyroid Carcinoma via promoting ubiquitination of XRCC5 to regulate the AKT signal pathway.

Wang L, Huang Y, Liu C, Guo M, Ma Z, He J, Wang A, Sun X, Liu Z
Journal of Cancer 2021;12(3):860-873

Elevated HNF1A expression promotes radiation-resistance via driving PI3K/AKT signaling pathway in esophageal squamous cell carcinoma cells.

Zou N, Zhang X, Li S, Li Y, Zhao Y, Yang X, Zhu S
Journal of Cancer 2021;12(16):5013-5024

An Essential NRP1-Mediated Role for Tagln2 in Gastric Cancer Angiogenesis.

Jin H, Zheng W, Hou J, Peng H, Zhuo H
Frontiers in oncology 2021;11:653246

miRNA-10a-5p inhibits cell metastasis in hepatocellular carcinoma via targeting SKA1.

Shen D, Zhao HY, Gu AD, Wu YW, Weng YH, Li SJ, Song JY, Gu XF, Qiu J, Zhao W
The Kaohsiung journal of medical sciences 2021 Sep;37(9):784-794

EFNA4 promotes cell proliferation and tumor metastasis in hepatocellular carcinoma through a PIK3R2/GSK3β/β-catenin positive feedback loop.

Lin J, Zeng C, Zhang J, Song Z, Qi N, Liu X, Zhang Z, Li A, Chen F
Molecular therapy. Nucleic acids 2021 Sep 3;25:328-341

Long noncoding RNA SGO1-AS1 inactivates TGFβ signaling by facilitating TGFB1/2 mRNA decay and inhibits gastric carcinoma metastasis.

Huang D, Zhang K, Zheng W, Zhang R, Chen J, Du N, Xia Y, Long Y, Gu Y, Xu J, Deng M
Journal of experimental & clinical cancer research : CR 2021 Oct 28;40(1):342

Erianin, the main active ingredient of Dendrobium chrysotoxum Lindl, inhibits precancerous lesions of gastric cancer (PLGC) through suppression of the HRAS-PI3K-AKT signaling pathway as revealed by network pharmacology and in vitro experimental verification.

Wang Y, Chu F, Lin J, Li Y, Johnson N, Zhang J, Gai C, Su Z, Cheng H, Wang L, Ding X
Journal of ethnopharmacology 2021 Oct 28;279:114399

Circular RNA circZFPM2 promotes epithelial-mesenchymal transition in endometriosis by regulating miR-205-5p/ZEB1 signalling pathway.

Wang D, Cui L, Yang Q, Wang J
Cellular signalling 2021 Nov;87:110145

Inhibition of Ras protein activator like 2 produces antitumor effects in gastric cancer via the suppression of YAP1 activation.

Hu Y, Zhang P, Shi Y, Dong X, Wu Y, Dong D, Li E, Fan Y
Environmental toxicology 2021 Nov 26;

miR-199b-5p-DDR1-ERK signalling axis suppresses prostate cancer metastasis via inhibiting epithelial-mesenchymal transition.

Zhao Z, Zhao S, Luo L, Xiang Q, Zhu Z, Wang J, Liu Y, Luo J
British journal of cancer 2021 Mar;124(5):982-994

Expression of Talin-1 in endometriosis and its possible role in pathogenesis.

Tang X, Li Q, Li L, Jiang J
Reproductive biology and endocrinology : RB&E 2021 Mar 9;19(1):42

YAP/TEAD4-induced KIF4A contributes to the progression and worse prognosis of esophageal squamous cell carcinoma.

Li Y, Zhu X, Yang M, Wang Y, Li J, Fang J, Guo W, Ma S, Guan F
Molecular carcinogenesis 2021 Jul;60(7):440-454

Parthenolide inhibits the tumor characteristics of renal cell carcinoma.

Liu D, Han Y, Liu L, Ren X, Zhang H, Fan S, Qin T, Li L
International journal of oncology 2021 Jan;58(1):100-110

Gastrin-17 induces gastric cancer cell epithelial-mesenchymal transition via the Wnt/β-catenin signaling pathway.

Li Y, Zhao Y, Li Y, Zhang X, Li C, Long N, Chen X, Bao L, Zhou J, Xie Y
Journal of physiology and biochemistry 2021 Feb;77(1):93-104

F-Box protein 4 inhibits progression of papillary thyroid cancer.

Xu M, Wang Y, Chen M, Hu H, Xia T, Deng D
Steroids 2021 Feb;166:108773

Pyrvinium pamoate inhibits cell proliferation through ROS-mediated AKT-dependent signaling pathway in colorectal cancer.

Zheng W, Hu J, Lv Y, Bai B, Shan L, Chen K, Dai S, Zhu H
Medical oncology (Northwood, London, England) 2021 Feb 8;38(2):21

MyD88 in myofibroblasts enhances colitis-associated tumorigenesis via promoting macrophage M2 polarization.

Yuan Q, Gu J, Zhang J, Liu S, Wang Q, Tian T, Chen Z, Zhang J
Cell reports 2021 Feb 2;34(5):108724

EPB41L5 promotes EMT through the ERK/p38 MAPK signaling pathway in esophageal squamous cell carcinoma.

Bao S, Ji Z, Shi M, Liu X
Pathology, research and practice 2021 Dec;228:153682

Reduced expression of miR-30c-5p promotes hepatocellular carcinoma progression by targeting RAB32.

He Z, Tian M, Fu X
Molecular therapy. Nucleic acids 2021 Dec 3;26:603-612

Urinary exosomes-based Engineered Nanovectors for Homologously Targeted Chemo-Chemodynamic Prostate Cancer Therapy via abrogating EGFR/AKT/NF-kB/IkB signaling.

Pan S, Zhang Y, Huang M, Deng Z, Zhang A, Pei L, Wang L, Zhao W, Ma L, Zhang Q, Cui D
Biomaterials 2021 Aug;275:120946

Osthole inhibits the migration and invasion of highly metastatic breast cancer cells by suppressing ITGα3/ITGβ5 signaling.

Chen YQ, Song HY, Zhou ZY, Ma J, Luo ZY, Zhou Y, Wang JY, Liu S, Han XH
Acta pharmacologica Sinica 2021 Aug 23;

EMT changes actin cortex rheology in a cell-cycle-dependent manner.

Hosseini K, Frenzel A, Fischer-Friedrich E
Biophysical journal 2021 Aug 17;120(16):3516-3526

LncRNA ABCC6P1 promotes proliferation and migration of papillary thyroid cancer cells via Wnt/β-catenin signaling pathway.

Guan Y, Li Y, Yang QB, Yu J, Qiao H
Annals of translational medicine 2021 Apr;9(8):664

AOC1 Contributes to Tumor Progression by Promoting the AKT and EMT Pathways in Gastric Cancer.

Xu F, Xu Y, Xiong JH, Zhang JH, Wu J, Luo J, Xiong JP
Cancer management and research 2020;12:1789-1798

3D printed in vitro tumor tissue model of colorectal cancer.

Chen H, Cheng Y, Wang X, Wang J, Shi X, Li X, Tan W, Tan Z
Theranostics 2020;10(26):12127-12143

EIF3H interacts with PDCD4 enhancing lung adenocarcinoma cell metastasis.

Hu Y, Wei X, Lv Y, Xie X, Yang L, He J, Tao X, Ma Y, Su Y, Wu L, Fang W, Liu Z
American journal of cancer research 2020;10(1):179-195

Pyruvate Kinase M2 Promotes Prostate Cancer Metastasis Through Regulating ERK1/2-COX-2 Signaling.

Guo W, Zhang Z, Li G, Lai X, Gu R, Xu W, Chen H, Xing Z, Chen L, Qian J, Xu S, Zeng F, Deng F
Frontiers in oncology 2020;10:544288

GBP1 promotes erlotinib resistance via PGK1‑activated EMT signaling in non‑small cell lung cancer.

Cheng L, Gou L, Wei T, Zhang J
International journal of oncology 2020 Sep;57(3):858-870

The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1.

Wei W, Ma XD, Jiang GM, Shi B, Zhong W, Sun CL, Zhao L, Hou YJ, Wang H
Oncology research 2020 Sep 1;28(4):423-438

Biomimetic Human Disease Model of SARS-CoV-2 Induced Lung Injury and Immune Responses on Organ Chip System.

Zhang M, Wang P, Luo R, Wang Y, Li Z, Guo Y, Yao Y, Li M, Tao T, Chen W, Han J, Liu H, Cui K, Zhang X, Zheng Y, Qin J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2020 Oct 24;:2002928

Circular RNA circNRIP1 promotes migration and invasion in cervical cancer by sponging miR-629-3p and regulating the PTP4A1/ERK1/2 pathway.

Li X, Ma N, Zhang Y, Wei H, Zhang H, Pang X, Li X, Wu D, Wang D, Yang Z, Zhang S
Cell death & disease 2020 May 26;11(5):399

Oxymatrine reverses 5-fluorouracil resistance by inhibition of colon cancer cell epithelial-mesenchymal transition and NF-κB signaling in vitro.

Liang L, Wu J, Luo J, Wang L, Chen ZX, Han CL, Gan TQ, Huang JA, Cai ZW
Oncology letters 2020 Jan;19(1):519-526

LacdiNAcylation of N-glycans in MDA-MB-231 human breast cancer cells results in changes in morphological appearance and adhesive properties of the cells.

Hirano K, Takada Y, Furukawa K
Histochemistry and cell biology 2020 Jan;153(1):17-26

Berberine inhibits proliferation and migration of colorectal cancer cells by downregulation of GRP78.

Gong C, Hu X, Xu Y, Yang J, Zong L, Wang C, Zhu J, Li Z, Lu D
Anti-cancer drugs 2020 Feb;31(2):141-149

A cross-talk between epithelium and endothelium mediates human alveolar-capillary injury during SARS-CoV-2 infection.

Wang P, Luo R, Zhang M, Wang Y, Song T, Tao T, Li Z, Jin L, Zheng H, Chen W, Zhao M, Zheng Y, Qin J
Cell death & disease 2020 Dec 8;11(12):1042

miR-145-5p suppresses proliferation, metastasis and EMT of colorectal cancer by targeting CDCA3.

Chen Q, Zhou L, Ye X, Tao M, Wu J
Pathology, research and practice 2020 Apr;216(4):152872

Stem Cells from Human Exfoliated Deciduous Teeth Ameliorate Diabetic Nephropathy In Vivo and In Vitro by Inhibiting Advanced Glycation End Product-Activated Epithelial-Mesenchymal Transition.

Rao N, Wang X, Xie J, Li J, Zhai Y, Li X, Fang T, Wang Y, Zhao Y, Ge L
Stem cells international 2019;2019:2751475

SIRT6/HIF-1α axis promotes papillary thyroid cancer progression by inducing epithelial-mesenchymal transition.

Yang Z, Yu W, Huang R, Ye M, Min Z
Cancer cell international 2019;19:17

VASN promotes YAP/TAZ and EMT pathway in thyroid carcinogenesis in vitro.

Bhandari A, Guan Y, Xia E, Huang Q, Chen Y
American journal of translational research 2019;11(6):3589-3599

Cinobufotalin powerfully reversed EBV-miR-BART22-induced cisplatin resistance via stimulating MAP2K4 to antagonize non-muscle myosin heavy chain IIA/glycogen synthase 3β/β-catenin signaling pathway.

Liu Y, Jiang Q, Liu X, Lin X, Tang Z, Liu C, Zhou J, Zhao M, Li X, Cheng Z, Li L, Xie Y, Liu Z, Fang W
EBioMedicine 2019 Oct;48:386-404

Knockdown of FAM64A suppresses proliferation and migration of breast cancer cells.

Yao Z, Zheng X, Lu S, He Z, Miao Y, Huang H, Chu X, Cai C, Zou F
Breast cancer (Tokyo, Japan) 2019 Nov;26(6):835-845

The contrary functions of lncRNA HOTAIR/miR-17-5p/PTEN axis and Shenqifuzheng injection on chemosensitivity of gastric cancer cells.

Jia J, Zhan D, Li J, Li Z, Li H, Qian J
Journal of cellular and molecular medicine 2019 Jan;23(1):656-669

miR-196a-5p promotes metastasis of colorectal cancer via targeting IκBα.

Xin H, Wang C, Liu Z
BMC cancer 2019 Jan 8;19(1):30

Silencing ubiquitin-conjugating enzyme 2C inhibits proliferation and epithelial-mesenchymal transition in pancreatic ductal adenocarcinoma.

Wang X, Yin L, Yang L, Zheng Y, Liu S, Yang J, Cui H, Wang H
The FEBS journal 2019 Dec;286(24):4889-4909

RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer.

Li Q, Lai Q, He C, Fang Y, Yan Q, Zhang Y, Wang X, Gu C, Wang Y, Ye L, Han L, Lin X, Chen J, Cai J, Li A, Liu S
Journal of experimental & clinical cancer research : CR 2019 Aug 1;38(1):334

Estrogen receptor β upregulates CCL2 via NF-κB signaling in endometriotic stromal cells and recruits macrophages to promote the pathogenesis of endometriosis.

Gou Y, Li X, Li P, Zhang H, Xu T, Wang H, Wang B, Ma X, Jiang X, Zhang Z
Human reproduction (Oxford, England) 2019 Apr 1;34(4):646-658

Association of doublecortin-like kinase 1 with tumor aggressiveness and poor biochemical recurrence-free survival in prostate cancer.

Jiang D, Xiao C, Xian T, Wang L, Mao Y, Zhang J, Pang J
OncoTargets and therapy 2018;11:1077-1086

The regulatory effects of metformin on the [SNAIL/miR-34]:[ZEB/miR-200] system in the epithelial-mesenchymal transition(EMT) for colorectal cancer(CRC).

Wang Y, Wu Z, Hu L
European journal of pharmacology 2018 Sep 5;834:45-53

The homeostasis-maintaining metabolites from bacterial stress response to bacteriophage infection suppress tumor metastasis.

He T, Jin M, Xu C, Ma Z, Wu F, Zhang X
Oncogene 2018 Oct;37(43):5766-5779

Evaluation of a Potential Clinical Significant Drug-Drug Interaction between Digoxin and Bupropion in Cynomolgus Monkeys.

Shen Y, Yu Y, Lai W, Li S, Xu Z, Jin J, Yan X, Xing H, Chen X, Xiong A, Xia C, He J, Hong K
Pharmaceutical research 2018 Nov 6;36(1):1

The molecular landscape of synchronous colorectal cancer reveals genetic heterogeneity.

Wang X, Fang H, Cheng Y, Li L, Sun X, Fu T, Huang P, Zhang A, Feng Z, Li C, Huang X, Li G, Du P, Yang H, Fang X, Li F, Gao Q, Liu B
Carcinogenesis 2018 May 3;39(5):708-718

Nogo-B receptor promotes epithelial-mesenchymal transition in non-small cell lung cancer cells through the Ras/ERK/Snail1 pathway.

Wu D, Zhao B, Qi X, Peng F, Fu H, Chi X, Miao QR, Shao S
Cancer letters 2018 Apr 1;418:135-146

Crocetin inhibits the proliferation, migration and TGF-β₂-induced epithelial-mesenchymal transition of retinal pigment epithelial cells.

Wang HF, Ma JX, Shang QL, An JB, Chen HT
European journal of pharmacology 2017 Nov 15;815:391-398

E-cadherin and ZEB2 modulate trophoblast cell differentiation during placental development in pigs.

Hong L, Han K, Wu K, Liu R, Huang J, Lunney JK, Zhao S, Yu M
Reproduction (Cambridge, England) 2017 Dec;154(6):765-775

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