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- Antibody Data
- Antigen structure
- References [12]
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- Western blot [1]
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- Product number
- 14149-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14149-1-AP, RRID:AB_2239222
- Product name
- SHMT1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SHMT1 antibody (Cat. #14149-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references De Novo Serine Synthesis Is a Metabolic Vulnerability That Can Be Exploited to Overcome Sunitinib Resistance in Advanced Renal Cell Carcinoma.
Candidate biomarkers in brown adipose tissue for post-mortem diagnosis of fatal hypothermia.
A study on the significance of serine hydroxymethyl transferase expression and its role in bladder cancer.
Differential Inhibition of Anaplerotic Pyruvate Carboxylation and Glutaminolysis-Fueled Anabolism Underlies Distinct Toxicity of Selenium Agents in Human Lung Cancer.
A siRNA screening of UBE2 family demonstrated that UBE2R1 had a high repressive effect on HIV Tat protein.
Proteomic and metabolomic analyses uncover sex-specific regulatory pathways in mouse fetal germline differentiation†.
Defective NADPH production in mitochondrial disease complex I causes inflammation and cell death.
SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy.
Vascular endothelial growth factor signaling requires glycine to promote angiogenesis.
Serine Is an Essential Metabolite for Effector T Cell Expansion.
mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle.
'Rod and ring' formation from IMP dehydrogenase is regulated through the one-carbon metabolic pathway.
Teisseire M, Sahu U, Parola J, Tsai MC, Vial V, Durivault J, Grépin R, Cormerais Y, Molina C, Gouraud A, Pagès G, Ben-Sahra I, Giuliano S
Cancer research 2025 May 15;85(10):1857-1873
Cancer research 2025 May 15;85(10):1857-1873
Candidate biomarkers in brown adipose tissue for post-mortem diagnosis of fatal hypothermia.
Zhang M, Wang N, Guo XS, Wang LL, Wang PF, Cao ZP, Zhang FY, Wang ZW, Guan DW, Zhao R
International journal of legal medicine 2024 Jan;138(1):61-72
International journal of legal medicine 2024 Jan;138(1):61-72
A study on the significance of serine hydroxymethyl transferase expression and its role in bladder cancer.
Su SW, Chen X, Wang G, Li P, Yang TX, Fang KW, Wu J, Li JM
Scientific reports 2024 Apr 9;14(1):8324
Scientific reports 2024 Apr 9;14(1):8324
Differential Inhibition of Anaplerotic Pyruvate Carboxylation and Glutaminolysis-Fueled Anabolism Underlies Distinct Toxicity of Selenium Agents in Human Lung Cancer.
Fan TW, Winnike J, Al-Attar A, Belshoff AC, Lorkiewicz PK, Tan JL, Wu M, Higashi RM, Lane AN
Metabolites 2023 Jun 21;13(7)
Metabolites 2023 Jun 21;13(7)
A siRNA screening of UBE2 family demonstrated that UBE2R1 had a high repressive effect on HIV Tat protein.
Xu M, Zhang J
Biochemistry and biophysics reports 2022 Dec;32:101366
Biochemistry and biophysics reports 2022 Dec;32:101366
Proteomic and metabolomic analyses uncover sex-specific regulatory pathways in mouse fetal germline differentiation†.
Hayashi Y, Mori M, Igarashi K, Tanaka K, Takehara A, Ito-Matsuoka Y, Kanai A, Yaegashi N, Soga T, Matsui Y
Biology of reproduction 2020 Oct 5;103(4):717-735
Biology of reproduction 2020 Oct 5;103(4):717-735
Defective NADPH production in mitochondrial disease complex I causes inflammation and cell death.
Balsa E, Perry EA, Bennett CF, Jedrychowski M, Gygi SP, Doench JG, Puigserver P
Nature communications 2020 Jun 1;11(1):2714
Nature communications 2020 Jun 1;11(1):2714
SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy.
Xu M, Moresco JJ, Chang M, Mukim A, Smith D, Diedrich JK, Yates JR 3rd, Jones KA
PLoS pathogens 2018 May;14(5):e1007071
PLoS pathogens 2018 May;14(5):e1007071
Vascular endothelial growth factor signaling requires glycine to promote angiogenesis.
Guo D, Murdoch CE, Xu H, Shi H, Duan DD, Ahmed A, Gu Y
Scientific reports 2017 Nov 7;7(1):14749
Scientific reports 2017 Nov 7;7(1):14749
Serine Is an Essential Metabolite for Effector T Cell Expansion.
Ma EH, Bantug G, Griss T, Condotta S, Johnson RM, Samborska B, Mainolfi N, Suri V, Guak H, Balmer ML, Verway MJ, Raissi TC, Tsui H, Boukhaled G, Henriques da Costa S, Frezza C, Krawczyk CM, Friedman A, Manfredi M, Richer MJ, Hess C, Jones RG
Cell metabolism 2017 Feb 7;25(2):345-357
Cell metabolism 2017 Feb 7;25(2):345-357
mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle.
Ben-Sahra I, Hoxhaj G, Ricoult SJH, Asara JM, Manning BD
Science (New York, N.Y.) 2016 Feb 12;351(6274):728-733
Science (New York, N.Y.) 2016 Feb 12;351(6274):728-733
'Rod and ring' formation from IMP dehydrogenase is regulated through the one-carbon metabolic pathway.
Calise SJ, Purich DL, Nguyen T, Saleem DA, Krueger C, Yin JD, Chan EK
Journal of cell science 2016 Aug 1;129(15):3042-52
Journal of cell science 2016 Aug 1;129(15):3042-52
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SHMT1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SHMT1. This antibody recognizes human, mouse, rat antigen. The SHMT1 antibody has been validated for the following applications: ELISA, WB analysis.
