Tissue expression
Cell line expression
Protein structure
SHMT1
Serine hydroxymethyltransferase 1CSHMT, MGC15229, MGC24556, SHMT
This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Top validated antibodies |
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Proteintech Group | 14149-1-AP | 10 references | Polyclonal |
WB
EL
ICC
IHC |
|
Novus Biologicals | NBP2-32173 | 1 references | Polyclonal |
WB
EL
IP
IHC |
|
antibodies-online | ABIN393802 | 5 references | Monoclonal |
WB
EL
IHC
|
|
Abnova Corporation | H00006470-M01 | 1 references | Monoclonal |
WB
EL
IHC
|
|
Atlas Antibodies | HPA023314 | 1 references | Polyclonal |
WB
ICC
IHC
|
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Supportive data in Antibodypedia
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Recommended by provider