Tissue expression
Cell line expression
Protein structure
SHMT1
Serine hydroxymethyltransferase 1CSHMT, MGC15229, MGC24556, SHMT
This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Top validated antibodies |
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Proteintech Group | ![]() |
10 references | Polyclonal |
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Novus Biologicals | ![]() |
1 references | Polyclonal |
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antibodies-online | ![]() |
5 references | Monoclonal |
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Abnova Corporation | ![]() |
1 references | Monoclonal |
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Atlas Antibodies | ![]() |
5 references | Polyclonal |
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