ADGRL1

gene product
CIRL1, KIAA0821, LEC2, LPHN1
This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Antibodypedia Validation Initiative

Validation method

Application

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Validated by best practice
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
107 antibodies from 22 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeAVIWBELICCIPIHCFC
Novus Biologicals
4 antibodies
antibodies-online
24 antibodies
GeneTex
4 antibodies
Aviva Systems Biology
2 antibodies
LifeSpan BioSciences, Inc.
34 antibodies
OriGene
4 antibodies
Biorbyt
7 antibodies
Abnova Corporation
5 antibodies
Invitrogen Antibodies
4 antibodies
Acris Antibodies GmbH
1 antibody
Atlas Antibodies
1 antibody
Bioworld Technology, Inc
1 antibody
NovoPro Bioscience Inc.
2 antibodies
Creative Diagnostics
2 antibodies
Abbkine
1 antibody
St John's Laboratory
1 antibody
Abgent
2 antibodies
GenWay
2 antibodies
RayBiotech, Inc.
2 antibodies
United States Biological
2 antibodies
MyBioSource
1 antibody
Sigma-Aldrich
1 antibody