MAB4591

antibody from R&D Systems

Targeting: TNFRSF11B OCIF, OPG, TR1

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

MAB4591

Provider

R&D Systems

Product name

Mouse Osteoprotegerin/TNFRSF11B Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. Detects mouse Osteoprotegerin/TNFRSF11B in ELISAs and Western blots. In Western blots, this antibody shows 100% cross-reactivity with recombinant human (rh) Osteoprotegerin and no cross-reactivity with rh4-1BB, recombinant mouse (rm) CD27, rmCD40, rhDR3, rhDR6, rmFas, rmGITR, rhHVEM, rhLT beta R, rmRANK, rmTNF RI, or rmTNF RII.

Reactivity

Mouse

Host

Rat

Conjugate

Unconjugated

Antigen sequence

Q6PI12


Isotype

IgG

Antibody clone number

110511

Vial size

500 ug

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

Cytokine-induced osteoprotegerin expression protects pancreatic beta cells through p38 mitogen-activated protein kinase signalling against cell death.

Schrader J, Rennekamp W, Niebergall U, Schoppet M, Jahr H, Brendel MD, Hörsch D, Hofbauer LC
Diabetologia 2007 Jun;50(6):1243-7

---

Serotonin and fluoxetine modulate bone cell function in vitro.

Gustafsson BI, Thommesen L, Stunes AK, Tommeras K, Westbroek I, Waldum HL, Slørdahl K, Tamburstuen MV, Reseland JE, Syversen U
Journal of cellular biochemistry 2006 May 1;98(1):139-51

---

17beta-estradiol (E2) modulates cytokine and chemokine expression in human monocyte-derived dendritic cells.

Bengtsson AK, Ryan EJ, Giordano D, Magaletti DM, Clark EA
Blood 2004 Sep 1;104(5):1404-10