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Protein structure
TNFRSF11B
TNF receptor superfamily member 11bOCIF, OPG, TR1
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Novus Biologicals |  NB100-56505 |
36 references | Monoclonal |
WB
EL
ICC
IP
IHC
FC
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| antibodies-online | ABIN252469 |
26 references | Monoclonal |
WB
ICC
IP
IHC
FC
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| R&D Systems | BAF805 |
4 references | Polyclonal |
WB
EL
ICC
IHC
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| Invitrogen Antibodies | PA5-86053 |
1 references | Polyclonal |
WB
ICC
IHC
OA
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| OriGene | AM06539SU-N |
Monoclonal |
WB
EL
ICC
FC
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