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Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- ABIN1842246 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Parkinson Protein 7 (PARK7) antibody
- Antibody type
- Monoclonal
- Antigen
- Other
- Reactivity
- Human, Rat, Bovine, Porcine
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 4H4
- Vial size
- 100 μL
Submitted references The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis.
Linking DJ-1 to neurodegeneration offers novel insights for understanding the pathogenesis of Parkinson's disease.
DJ-1 has a role in antioxidative stress to prevent cell death.
Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition.
Xu J, Zhong N, Wang H, Elias JE, Kim CY, Woldman I, Pifl C, Gygi SP, Geula C, Yankner BA
Human molecular genetics 2005 May 1;14(9):1231-41
Human molecular genetics 2005 May 1;14(9):1231-41
Linking DJ-1 to neurodegeneration offers novel insights for understanding the pathogenesis of Parkinson's disease.
Bonifati V, Oostra BA, Heutink P
Journal of molecular medicine (Berlin, Germany) 2004 Mar;82(3):163-74
Journal of molecular medicine (Berlin, Germany) 2004 Mar;82(3):163-74
DJ-1 has a role in antioxidative stress to prevent cell death.
Taira T, Saito Y, Niki T, Iguchi-Ariga SM, Takahashi K, Ariga H
EMBO reports 2004 Feb;5(2):213-8
EMBO reports 2004 Feb;5(2):213-8
Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition.
Yokota T, Sugawara K, Ito K, Takahashi R, Ariga H, Mizusawa H
Biochemical and biophysical research communications 2003 Dec 26;312(4):1342-8
Biochemical and biophysical research communications 2003 Dec 26;312(4):1342-8
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot of whole HeLa cell lysates probe with ABIN1842246 antibody to DJ-1. Numbers at right indicate molecular weight in kiloDaltons of protein standards. The strong single band running at about 21 kDa corresponds to DJ-1.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- HeLa cells stained with ABIN1842246 (green), and CPCA-Vim chicken antibody to vimentin (red) and DNA (blue). ABIN1842246 antibody reveals strong cytoplasmic staining for DJ-1.
