Tissue expression
Cell line expression
Protein structure
PARK7
Parkinsonism associated deglycaseDJ-1, DJ1, GATD2
The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | ![]() |
18 references | Polyclonal |
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Novus Biologicals | ![]() |
16 references | Polyclonal |
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LSBio | ![]() |
Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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GeneTex | ![]() |
2 references | Monoclonal |
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