BS6091

antibody from Bioworld Technology, Inc
Targeting: PARK7 DJ-1, DJ1, GATD2
Provider product page for BS6091
Western blot
Immunocytochemistry
Immunoprecipitation
Immunohistochemistry

Antibody data

Product number
BS6091 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PARK7 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human PARK7.
Description
The DJ-1 gene encodes a highly-conserved protein which is implicated in a number of cell processes. DJ-1 was first identified as a novel oncogene that transformed mouse NIH/3T3 cells in cooperation with activated Ras. Additionally, DJ-1 was cloned in rat as SP22 or CAP-1, and found to be an infertilityrelated sperm protein whose expression is reduced in sperm treated with toxicants. DJ-1 also positively regulates the androgen receptor (AR) by forming a complex with PIASxÏ«, a negative regulator of AR. The gene encoding human DJ-1 maps to chromosome 1p36.33-p36.12, a region identified as a hot spot of chromosome abnormalities in several tumor cells. Subsequently, mutations in the DJ-1 gene have been implicated in Parkinson£ªs disease, and loss of DJ-1 function leads to neurodegeneration.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PARK7 protein structure - BS6091 shown in red.