Antibody data
- Antibody Data
- Antigen structure
- References [1]
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- Product number
- M00757 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-PARK7/Dj 1 Rabbit Monoclonal Antibody
- Antibody type
- Monoclonal
- Description
- Monoclonal antibody for DJ 1/PARK7 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: Flow Cytometry, IP, IF, IHC, ICC, WB. Reactive species: Human, Mouse, Rat DJ 1/PARK7 information: Molecular Weight: 19891 MW; Subcellular Localization: Cell membrane ; Lipid-anchor . Cytoplasm . Nucleus . Membrane raft . Mitochondrion . Under normal conditions, located predominantly in the cytoplasm and, to a lesser extent, in the nucleus and mitochondrion. Translocates to the mitochondrion and subsequently to the nucleus in response to oxidative stress and exerts an increased cytoprotective effect against oxidative damage (PubMed:18711745). Detected in tau inclusions in brains from neurodegenerative disease patients (PubMed:14705119). Membrane raft localization in astrocytes and neuronal cells requires palmitoylation; Tissue Specificity: Highly expressed in pancreas, kidney, skeletal muscle, liver, testis and heart. Detected at slightly lower levels in placenta and brain (at protein level). Detected in astrocytes, Sertoli cells, spermatogonia, spermatids and spermatozoa.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Antibody clone number
- GAE-16
- Vial size
- 100ug/vial
- Concentration
- 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
- Storage
- At -20°C for one year. Avoid repeated freezing and thawing.
Submitted references Neural stem cell secretome exerts a protective effect on damaged neuron mitochondria in Parkinson's disease model.
Ni W, Zhou J, Ling Y, Lu X, Niu D, Zeng Y, Qiu Y, Si Y, Wang J, Zhang W, Wang Z, Hu J
Brain research 2022 Sep 1;1790:147978
Brain research 2022 Sep 1;1790:147978
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