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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
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- Product number
- MAB1076 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB1076, RRID:AB_1578424
- Product name
- PARK7 monoclonal antibody, clone 1B11
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against full length recombinant PARK7.
- Isotype
- IgG
- Antibody clone number
- 1B11
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references DJ-1 is present in a large molecular complex in human brain tissue and interacts with alpha-synuclein.
Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death.
DJ-1 up-regulates glutathione synthesis during oxidative stress and inhibits A53T alpha-synuclein toxicity.
Meulener MC, Graves CL, Sampathu DM, Armstrong-Gold CE, Bonini NM, Giasson BI
Journal of neurochemistry 2005 Jun;93(6):1524-32
Journal of neurochemistry 2005 Jun;93(6):1524-32
Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death.
Junn E, Taniguchi H, Jeong BS, Zhao X, Ichijo H, Mouradian MM
Proceedings of the National Academy of Sciences of the United States of America 2005 Jul 5;102(27):9691-6
Proceedings of the National Academy of Sciences of the United States of America 2005 Jul 5;102(27):9691-6
DJ-1 up-regulates glutathione synthesis during oxidative stress and inhibits A53T alpha-synuclein toxicity.
Zhou W, Freed CR
The Journal of biological chemistry 2005 Dec 30;280(52):43150-8
The Journal of biological chemistry 2005 Dec 30;280(52):43150-8
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- Experimental details
- Western blot analysis of Jurkat cell lysate was resolved by SDS - PAGE , transferred to PVDF membrane and probed with PARK7 monoclonal antibody , clone 1B11 (1 : 1000) (Cat # MAB1076) . Protein was visualized using a goat anti - mouse secondary antibody conjugated to HRP and an ECL detection system.
