Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- ABIN121180 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Parkinson Protein 7 (PARK7) antibody
- Antibody type
- Monoclonal
- Antigen
- Recombinant human GST-DJ1 (1-189 aa) purified from E. coli
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 1B11
- Vial size
- 0.1 mL
- Concentration
- 1.0 mg/ml
- Storage
- Can be stored at 2-8°C for up to one month, but store at -20°C for long term storage. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Submitted references DJ-1 is present in a large molecular complex in human brain tissue and interacts with alpha-synuclein.
Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death.
DJ-1 up-regulates glutathione synthesis during oxidative stress and inhibits A53T alpha-synuclein toxicity.
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism.
Meulener MC, Graves CL, Sampathu DM, Armstrong-Gold CE, Bonini NM, Giasson BI
Journal of neurochemistry 2005 Jun;93(6):1524-32
Journal of neurochemistry 2005 Jun;93(6):1524-32
Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death.
Junn E, Taniguchi H, Jeong BS, Zhao X, Ichijo H, Mouradian MM
Proceedings of the National Academy of Sciences of the United States of America 2005 Jul 5;102(27):9691-6
Proceedings of the National Academy of Sciences of the United States of America 2005 Jul 5;102(27):9691-6
DJ-1 up-regulates glutathione synthesis during oxidative stress and inhibits A53T alpha-synuclein toxicity.
Zhou W, Freed CR
The Journal of biological chemistry 2005 Dec 30;280(52):43150-8
The Journal of biological chemistry 2005 Dec 30;280(52):43150-8
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism.
Bonifati V, Rizzu P, van Baren MJ, Schaap O, Breedveld GJ, Krieger E, Dekker MC, Squitieri F, Ibanez P, Joosse M, van Dongen JW, Vanacore N, van Swieten JC, Brice A, Meco G, van Duijn CM, Oostra BA, Heutink P
Science (New York, N.Y.) 2003 Jan 10;299(5604):256-9
Science (New York, N.Y.) 2003 Jan 10;299(5604):256-9
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