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LearnPA1-16598
antibody from Invitrogen Antibodies
Targeting: DERL1
DER-1, DER1, derlin-1, FLJ13784, MGC3067, PRO2577
Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Immunohistochemistry [1]
- Other assay [1]
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- Product number
- PA1-16598 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- DERL1 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- This antibody is predicted to react with xenopus, bovine, chicken, rat, zebrafish, and mouse based on 100% sequence homology. Suggested positive control: antigen standard for DERL1 (transient overexpression lysate), KRM (canine microsome) lysates.
- Reactivity
- Human, Mouse, Canine, Hamster
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 1 mg/mL
- Storage
- 4°C, do not freeze
Submitted references Whole genome expression profiling associates activation of unfolded protein response with impaired production and release of epinephrine after recurrent hypoglycemia.
Kim JL, La Gamma EF, Estabrook T, Kudrick N, Nankova BB
PloS one 2017;12(2):e0172789
PloS one 2017;12(2):e0172789
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of DERL1 in human liver. Samples were incubated in DERL1 polyclonal antibody (Product # PA1-16598).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Fig 9 Western blot analysis confirms activation of UPR following RH. Total protein lysates from the right adrenal medulla of saline (2RS) and RH groups (2RH) were subjected to Western blot analyses as described in methods. Proteins were separated by SDS-PAGE, electroblotted and the membranes were sequentially probed with antibodies specific to Grp78, Derlin1, TH and GAPDH. Similar results were obtained in two separate replicate experiments.
