DERL1

gene product
DER-1, DER1, derlin-1, FLJ13784, MGC3067, PRO2577
The protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance regulator protein (CFTR) for degradation as well as unfolded proteins in Alzheimer's disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
232 antibodies from 26 providers.

Antibody properties

General

Applications

or Cancel
Antibody
antibodies-online
81 antibodies
Novus Biologicals
25 antibodies
Invitrogen Antibodies
4 antibodies
Biorbyt
8 antibodies
Aviva Systems Biology
2 antibodies
GeneTex
3 antibodies
OriGene
3 antibodies
Acris Antibodies GmbH
3 antibodies
Atlas Antibodies
1 antibody
NovoPro Bioscience Inc.
1 antibody
LifeSpan BioSciences, Inc.
50 antibodies
Abnova Corporation
4 antibodies
Bethyl Laboratories
1 antibody
ProSci
1 antibody
Abbkine Scientific Co.Ltd.
1 antibody
Cell Signaling Technology, Inc
1 antibody
RabMAbs
1 antibody
Creative Diagnostics
3 antibodies
MyBioSource
2 antibodies
Creative Biolabs
4 antibodies
St John's Laboratory
2 antibodies
Boster Biological Technology
1 antibody
Leading Biology
1 antibody
Sigma-Aldrich
2 antibodies
United States Biological
12 antibodies