Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB18134 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB18134, RRID:AB_10716789
- Product name
- RAD17 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of RAD17.
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Chromatin association of rad17 is required for an ataxia telangiectasia and rad-related kinase-mediated S-phase checkpoint in response to low-dose ultraviolet radiation.
Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin.
Phosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated and is required for G(1)/S checkpoint activation in response to DNA damage.
Garg R, Callens S, Lim DS, Canman CE, Kastan MB, Xu B
Molecular cancer research : MCR 2004 Jun;2(6):362-9
Molecular cancer research : MCR 2004 Jun;2(6):362-9
Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin.
Zou L, Cortez D, Elledge SJ
Genes & development 2002 Jan 15;16(2):198-208
Genes & development 2002 Jan 15;16(2):198-208
Phosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated and is required for G(1)/S checkpoint activation in response to DNA damage.
Post S, Weng YC, Cimprich K, Chen LB, Xu Y, Lee EY
Proceedings of the National Academy of Sciences of the United States of America 2001 Nov 6;98(23):13102-7
Proceedings of the National Academy of Sciences of the United States of America 2001 Nov 6;98(23):13102-7
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of extracts from A-549 cells, using RAD17 polyclonal antibody (Cat # PAB18134).Peptide "+" means "peptide blocking".
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunofluorescence analysis of A-549 cells, using RAD17 polyclonal antibody (Cat # PAB18134).Peptide "+" means "peptide blocking".
- Validation comment
- Immunofluorescence
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using RAD17 polyclonal antibody (Cat # PAB18134).Peptide "+" means "peptide blocking".
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)