RAD17

gene product
CCYC, RAD17Sp, Rad24
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Multiple alternatively spliced transcript variants of this gene, which encode four distinct protein isoforms, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified. [provided by RefSeq, Jul 2013]
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493 antibodies from 36 providers.

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AntibodyRefsTypeAVIWBELICCIPIHCFC
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antibodies-online
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Aviva Systems Biology
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Proteintech Group
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Affinity Biosciences
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St John's Laboratory
5 antibodies
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Invitrogen Antibodies
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Bioworld Technology, Inc
3 antibodies
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5 antibodies
Abbkine Scientific Co.Ltd.
4 antibodies
Cell Signaling Technology, Inc
3 antibodies
MyBioSource
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ProSci
2 antibodies
RabMAbs
4 antibodies
Creative Diagnostics
8 antibodies
Boster Biological Technology
1 antibody
United States Biological
67 antibodies
Sigma-Aldrich
5 antibodies
GenWay
7 antibodies
Abbiotec
1 antibody
Active Motif
1 antibody
Abbexa
3 antibodies
Creative Biolabs
2 antibodies
RayBiotech, Inc.
1 antibody