Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 10390-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10390-1-AP, RRID:AB_2118914
- Product name
- HGS antibody
- Antibody type
- Polyclonal
- Description
- HGS antibody (Cat. #10390-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Upregulation of the ESCRT pathway and multivesicular bodies accelerates degradation of proteins associated with neurodegeneration.
GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis.
Enterovirus 71 non-structural protein 3A hijacks vacuolar protein sorting 25 to boost exosome biogenesis to facilitate viral replication.
Neutral sphingomyelinase 2 controls exosome secretion by counteracting V-ATPase-mediated endosome acidification.
Compartmentalization of casein kinase 1 γ CSNK1G controls the intracellular trafficking of ceramide.
VPS28 regulates brain vasculature by controlling neuronal VEGF trafficking through extracellular vesicle secretion.
Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes.
The interferon-stimulated exosomal hACE2 potently inhibits SARS-CoV-2 replication through competitively blocking the virus entry.
RAB31 marks and controls an ESCRT-independent exosome pathway.
β-defensin 1 expression in HCV infected liver/liver cancer: an important role in protecting HCV progression and liver cancer development.
The ubiquitin ligase deltex-3l regulates endosomal sorting of the G protein-coupled receptor CXCR4.
Benyair R, Giridharan SSP, Rivero-Ríos P, Hasegawa J, Bristow E, Eskelinen EL, Shmueli MD, Fishbain-Yoskovitz V, Merbl Y, Sharkey LM, Paulson HL, Hanson PI, Patnaik S, Al-Ramahi I, Botas J, Marugan J, Weisman LS
Autophagy reports 2023;2(1)
Autophagy reports 2023;2(1)
GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis.
Lee YJ, Shin KJ, Jang HJ, Ryu JS, Lee CY, Yoon JH, Seo JK, Park S, Lee S, Je AR, Huh YH, Kong SY, Kwon T, Suh PG, Chae YC
Developmental cell 2023 Feb 27;58(4):320-334.e8
Developmental cell 2023 Feb 27;58(4):320-334.e8
Enterovirus 71 non-structural protein 3A hijacks vacuolar protein sorting 25 to boost exosome biogenesis to facilitate viral replication.
Ruan Z, Liang Y, Chen Z, Yin J, Li C, Pan P, Zhang Q, Wu J, Luo Z
Frontiers in microbiology 2022;13:1024899
Frontiers in microbiology 2022;13:1024899
Neutral sphingomyelinase 2 controls exosome secretion by counteracting V-ATPase-mediated endosome acidification.
Choezom D, Gross JC
Journal of cell science 2022 Mar 1;135(5)
Journal of cell science 2022 Mar 1;135(5)
Compartmentalization of casein kinase 1 γ CSNK1G controls the intracellular trafficking of ceramide.
Goto A, Sakai S, Mizuike A, Yamaji T, Hanada K
iScience 2022 Jul 15;25(7):104624
iScience 2022 Jul 15;25(7):104624
VPS28 regulates brain vasculature by controlling neuronal VEGF trafficking through extracellular vesicle secretion.
Dong X, Jiang D, Wang L, Zhao J, Yu L, Huang Y, Wu X, Zhu Y, Zhao Y, Zhao Q, Zhang G, Li X
iScience 2022 Apr 15;25(4):104042
iScience 2022 Apr 15;25(4):104042
Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes.
Kazan JM, Desrochers G, Martin CE, Jeong H, Kharitidi D, Apaja PM, Roldan A, St Denis N, Gingras AC, Lukacs GL, Pause A
iScience 2021 Nov 19;24(11):103274
iScience 2021 Nov 19;24(11):103274
The interferon-stimulated exosomal hACE2 potently inhibits SARS-CoV-2 replication through competitively blocking the virus entry.
Zhang J, Huang F, Xia B, Yuan Y, Yu F, Wang G, Chen Q, Wang Q, Li Y, Li R, Song Z, Pan T, Chen J, Lu G, Zhang H
Signal transduction and targeted therapy 2021 May 12;6(1):189
Signal transduction and targeted therapy 2021 May 12;6(1):189
RAB31 marks and controls an ESCRT-independent exosome pathway.
Wei D, Zhan W, Gao Y, Huang L, Gong R, Wang W, Zhang R, Wu Y, Gao S, Kang T
Cell research 2021 Feb;31(2):157-177
Cell research 2021 Feb;31(2):157-177
β-defensin 1 expression in HCV infected liver/liver cancer: an important role in protecting HCV progression and liver cancer development.
Ling YM, Chen JY, Guo L, Wang CY, Tan WT, Wen Q, Zhang SD, Deng GH, Lin Y, Kwok HF
Scientific reports 2017 Oct 17;7(1):13404
Scientific reports 2017 Oct 17;7(1):13404
The ubiquitin ligase deltex-3l regulates endosomal sorting of the G protein-coupled receptor CXCR4.
Holleman J, Marchese A
Molecular biology of the cell 2014 Jun 15;25(12):1892-904
Molecular biology of the cell 2014 Jun 15;25(12):1892-904
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HGS antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HGS. This antibody recognizes human, mouse antigen. The HGS antibody has been validated for the following applications: ELISA, WB analysis.