Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
Comment
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- Product number
- PAB4227 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB4227, RRID:AB_1575947
- Product name
- HGS polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of HGS.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references GRIF1 binds Hrs and is a new regulator of endosomal trafficking.
Involvement of Hgs/Hrs in signaling for cytokine-mediated c-fos induction through interaction with TAK1 and Pak1.
Hgs (Hrs), a FYVE domain protein, is involved in Smad signaling through cooperation with SARA.
Kirk E, Chin LS, Li L
Journal of cell science 2006 Nov 15;119(Pt 22):4689-701
Journal of cell science 2006 Nov 15;119(Pt 22):4689-701
Involvement of Hgs/Hrs in signaling for cytokine-mediated c-fos induction through interaction with TAK1 and Pak1.
Sasaki Y, Sugamura K
The Journal of biological chemistry 2001 Aug 10;276(32):29943-52
The Journal of biological chemistry 2001 Aug 10;276(32):29943-52
Hgs (Hrs), a FYVE domain protein, is involved in Smad signaling through cooperation with SARA.
Miura S, Takeshita T, Asao H, Kimura Y, Murata K, Sasaki Y, Hanai JI, Beppu H, Tsukazaki T, Wrana JL, Miyazono K, Sugamura K
Molecular and cellular biology 2000 Dec;20(24):9346-55
Molecular and cellular biology 2000 Dec;20(24):9346-55
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- The HGS polyclonal antibody (Cat # PAB4227) is used in Western blot to detect HGS in HL-60 cell lysate .
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with HGS polyclonal antibody (Cat # PAB4227) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated . BC = breast carcinoma .
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)