Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS7852 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- GRN polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human GRN.
- Description
- ?Acrogranin (also designated PC cell-derived growth factor (PCDGF), epithelin/granulin precursor or paragranulin) is a glycosylated protein originally purified from the highly tumorigenic, Insulin-independent mouse teratoma PC cell line. Acrogranin is a cysteine-rich molecule whose expression is essential for tumorigenicity in teratoma cells. Acrogranin is expressed in estrogen receptor-positive (ER(+)) human mammary MDA-MB-468 epithelial cells, human breast cancer MCF7 cells and human estrogen-responsive T-47D cells. Secreted acrogranin acts as an autocrine growth factor for breast carcinoma cells and overexpression may play an important role in human breast cancer. Acrogranin stimulates the growth of PC cells as well as 3T3 fibroblasts.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- WesternBlot (WB) analysis of GRN polyclonal antibody