Tissue expression
Cell line expression
Protein structure

GRN

Granulin precursor
CLN11, PCDGF, PGRN 
Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. [provided by RefSeq, Jul 2008]
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715 antibodies from 38 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
7 antibodies
Proteintech Group
7 antibodies
Novus Biologicals
107 antibodies
R&D Systems
13 antibodies
Atlas Antibodies
4 antibodies
GeneTex
6 antibodies
Biorbyt
62 antibodies
antibodies-online
137 antibodies
NovoPro Bioscience Inc.
11 antibodies
Abnova Corporation
8 antibodies
Affinity Biosciences
1 antibody
Everest Biotech
2 antibodies
FineTest Biotech
3 antibodies
St John's Laboratory
6 antibodies
Cusabio Biotech Co., Ltd
2 antibodies
Abgent
4 antibodies
OriGene
23 antibodies
Aviva Systems Biology
4 antibodies
Bioworld Technology, Inc
1 antibody
MilliporeSigma / Merck KGaA
6 antibodies
Antibodies.com
2 antibodies
RabMAbs
4 antibodies
Boster Biological Technology
1 antibody
NSJ Bioreagents
2 antibodies
Acris Antibodies GmbH
2 antibodies
MyBioSource
10 antibodies
Sino Biological Inc.
8 antibodies
Arigo
1 antibody
Abbexa
9 antibodies
ProSci
5 antibodies
Creative Biolabs
40 antibodies
Abbiotec
1 antibody
United States Biological
61 antibodies
Leading Biology
5 antibodies
Creative Diagnostics
6 antibodies
Enzo Life Sciences
1 antibody