ABIN358460

antibody from antibodies-online

Targeting: DAXX DAP6

ELISA (Recommended by provider)

Antibody Data

Product number

ABIN358460

Provider

antibodies-online

Product name

anti-Death-Domain Associated Protein (DAXX) (pSer671) antibody

Antibody type

Polyclonal

Antigen

This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S671 of human DAXX.

Description

Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.

Reactivity

Human

Host

Rabbit

Epitope

pSer671

Vial size

0.4 mL

Concentration

0.25 mg/mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Daxx mediates the small ubiquitin-like modifier-dependent transcriptional repression of Smad4.

Chang CC, Lin DY, Fang HI, Chen RH, Shih HM
The Journal of biological chemistry 2005 Mar 18;280(11):10164-73

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Interaction between the human cytomegalovirus UL82 gene product (pp71) and hDaxx regulates immediate-early gene expression and viral replication.

Cantrell SR, Bresnahan WA
Journal of virology 2005 Jun;79(12):7792-802

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The cellular protein daxx interacts with avian sarcoma virus integrase and viral DNA to repress viral transcription.

Greger JG, Katz RA, Ishov AM, Maul GG, Skalka AM
Journal of virology 2005 Apr;79(8):4610-8

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The transcriptional repressor hDaxx potentiates p53-dependent apoptosis.

Gostissa M, Morelli M, Mantovani F, Guida E, Piazza S, Collavin L, Brancolini C, Schneider C, Del Sal G
The Journal of biological chemistry 2004 Nov 12;279(46):48013-23

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Large-scale characterization of HeLa cell nuclear phosphoproteins.

Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP
Proceedings of the National Academy of Sciences of the United States of America 2004 Aug 17;101(33):12130-5