DAXX

gene product
DAP6
This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Antibodypedia Validation Initiative

Validation method

Application

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
778 antibodies from 42 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeAVIWBELICCIPIHCFC
Atlas Antibodies
3 antibodies
Novus Biologicals
57 antibodies
antibodies-online
259 antibodies
Abnova Corporation
15 antibodies
GeneTex
9 antibodies
Biorbyt
33 antibodies
Acris Antibodies GmbH
24 antibodies
LifeSpan BioSciences, Inc.
113 antibodies
OriGene
12 antibodies
Affinity Biosciences
4 antibodies
Boster Biological Technology
5 antibodies
NSJ Bioreagents
2 antibodies
Invitrogen Antibodies
10 antibodies
Aviva Systems Biology
12 antibodies
Bioworld Technology, Inc
2 antibodies
Proteintech Group
1 antibody
NovoPro Bioscience Inc.
3 antibodies
Abgent
7 antibodies
Antibodies.com
2 antibodies
St John's Laboratory
4 antibodies
Bethyl Laboratories
1 antibody
Arigo
3 antibodies
BioLegend
3 antibodies
Enzo Life Sciences
1 antibody
Abbkine Scientific Co.Ltd.
3 antibodies
RabMAbs
3 antibodies
ProSci
3 antibodies
Cell Signaling Technology, Inc
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
MyBioSource
12 antibodies
Creative Biolabs
5 antibodies
Creative Diagnostics
6 antibodies
RayBiotech, Inc.
2 antibodies
EMD Millipore
2 antibodies
R&D Systems
1 antibody
United States Biological
69 antibodies
Abiocode, Inc.
2 antibodies
Abbexa
2 antibodies
Abbiotec
1 antibody
GenWay
5 antibodies
Sigma-Aldrich
3 antibodies