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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Product number
- ABIN501203 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Death-Domain Associated Protein (DAXX) (AA 558-740), (C-Term) antibody
- Antibody type
- Monoclonal
- Description
- Protein-A Sepharose Chromatography of hybridoma supernatant.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- C-Term, AA 558-740
- Isotype
- IgG
- Antibody clone number
- DAXX-01
- Vial size
- 0.1 mg
- Storage
- Store lyophilized (preferably in a desiccator) at -20°C and in aliquots at -80°C. Reconstituted antibody can be stored at 4°C for a limited period of time, it does not show decline in activity after two weeks at 4°C.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Modification of nuclear PML protein by SUMO-1 regulates Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts.
PML nuclear bodies are highly organised DNA-protein structures with a function in heterochromatin remodelling at the G2 phase.
The insulin-sensitive glucose transporter, GLUT4, interacts physically with Daxx. Two proteins with capacity to bind Ubc9 and conjugated to SUMO1.
Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channel.
Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs).
Meinecke I, Cinski A, Baier A, Peters MA, Dankbar B, Wille A, Drynda A, Mendoza H, Gay RE, Hay RT, Ink B, Gay S, Pap T
Proceedings of the National Academy of Sciences of the United States of America 2007 Mar 20;104(12):5073-8
Proceedings of the National Academy of Sciences of the United States of America 2007 Mar 20;104(12):5073-8
PML nuclear bodies are highly organised DNA-protein structures with a function in heterochromatin remodelling at the G2 phase.
Luciani JJ, Depetris D, Usson Y, Metzler-Guillemain C, Mignon-Ravix C, Mitchell MJ, Megarbane A, Sarda P, Sirma H, Moncla A, Feunteun J, Mattei MG
Journal of cell science 2006 Jun 15;119(Pt 12):2518-31
Journal of cell science 2006 Jun 15;119(Pt 12):2518-31
The insulin-sensitive glucose transporter, GLUT4, interacts physically with Daxx. Two proteins with capacity to bind Ubc9 and conjugated to SUMO1.
Lalioti VS, Vergarajauregui S, Pulido D, Sandoval IV
The Journal of biological chemistry 2002 May 31;277(22):19783-91
The Journal of biological chemistry 2002 May 31;277(22):19783-91
Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channel.
Snyder PM, Olson DR, Thomas BC
The Journal of biological chemistry 2002 Jan 4;277(1):5-8
The Journal of biological chemistry 2002 Jan 4;277(1):5-8
Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs).
Torii S, Egan DA, Evans RA, Reed JC
The EMBO journal 1999 Nov 1;18(21):6037-49
The EMBO journal 1999 Nov 1;18(21):6037-49
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