Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB3676 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB3676, RRID:AB_1571738
- Product name
- BMP7 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of BMP7.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Alterations in endogenous osteogenic protein-1 with degeneration of human articular cartilage.
The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly.
Bone morphogenetic protein-7 reduces the severity of colon tissue damage and accelerates the healing of inflammatory bowel disease in rats.
Merrihew C, Kumar B, Heretis K, Rueger DC, Kuettner KE, Chubinskaya S
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2003 Sep;21(5):899-907
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2003 Sep;21(5):899-907
The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly.
Greenwald J, Groppe J, Gray P, Wiater E, Kwiatkowski W, Vale W, Choe S
Molecular cell 2003 Mar;11(3):605-17
Molecular cell 2003 Mar;11(3):605-17
Bone morphogenetic protein-7 reduces the severity of colon tissue damage and accelerates the healing of inflammatory bowel disease in rats.
Maric I, Poljak L, Zoricic S, Bobinac D, Bosukonda D, Sampath KT, Vukicevic S
Journal of cellular physiology 2003 Aug;196(2):258-64
Journal of cellular physiology 2003 Aug;196(2):258-64
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of BMP7 polyclonal antibody (Cat # PAB3676). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the Bmp7 gene (Lane 2) (Origene Technologies).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with BMP7 polyclonal antibody (Cat # PAB3676) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)