BMP7

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity. [provided by RefSeq, Jul 2008]

Description

bone morphogenetic protein 7

Protein family

Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Predicted secreted proteins, Protein evidence (Ezkurdia et al 2014)

Chromosome

20:q13.31 (57168748 - 57266629)

Ensembl ID

ENSG00000101144  (ver. 84.38)

Orthologs

Mouse Bmp7: ENSMUSG00000008999

UniProt

P18075

neXtProt

NX_P18075

Human splice variants
Mouse splice variants