Antibody data
- Antibody Data
 - Antigen structure
 - References [10]
 - Comments [0]
 - Validations
 - Immunocytochemistry [1]
 - Immunohistochemistry [1]
 
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Validation data
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- Product number
 - HPA002896 - Provider product page

 - Provider
 - Atlas Antibodies
 - Proper citation
 - Atlas Antibodies Cat#HPA002896, RRID:AB_1079459
 - Product name
 - Anti-NDRG2
 - Antibody type
 - Polyclonal
 - Description
 - Polyclonal Antibody against Human NDRG2, Gene description: NDRG family member 2, Alternative Gene Names: KIAA1248, SYLD, Validated applications: ICC, IHC, WB, Uniprot ID: Q9UN36, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
 - Reactivity
 - Human
 - Host
 - Rabbit
 - Conjugate
 - Unconjugated
 - Isotype
 - IgG
 - Vial size
 - 100 µl
 - Concentration
 - 0.3 mg/ml
 - Storage
 - Store at +4°C for short term storage. Long time storage is recommended at -20°C.
 - Handling
 - The antibody solution should be gently mixed before use.
 
Submitted references		Developmentally Arrested Basket/Stellate Cells in Postnatal Human Brain as Potential Tumor Cells of Origin for Cerebellar Hemangioblastoma in von Hippel-Lindau Patients
				
Lactate attenuates astrocytic inflammation by inhibiting ubiquitination and degradation of NDRG2 under oxygen–glucose deprivation conditions
				
Lamina-specific properties of spinal astrocytes.
				
MicroRNA suppression of stress-responsive NDRG2 during dexamethasone treatment in skeletal muscle cells
				
Abundant NDRG2 Expression Is Associated with Aggressiveness and Unfavorable Patients' Outcome in Basal-Like Breast Cancer.
				
NDRG2 promotes myoblast proliferation and caspase 3/7 activities during differentiation, and attenuates hydrogen peroxide – But not palmitate‐induced toxicity
				
Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells
				
NDRG4 Is Required for Cell Cycle Progression and Survival in Glioblastoma Cells
				
Tissue profiling of the mammalian central nervous system using human antibody-based proteomics.
				
Frequent promoter hypermethylation and transcriptional downregulation of the NDRG2 gene at 14q11.2 in primary glioblastoma
				
		
	
			Shively S, Edwards N, MacDonald T, Johnson K, Diaz-Rodriguez N, Merrill M, Vortmeyer A
Journal of Neuropathology & Experimental Neurology 2022;81(11):885-899
		Journal of Neuropathology & Experimental Neurology 2022;81(11):885-899
Lactate attenuates astrocytic inflammation by inhibiting ubiquitination and degradation of NDRG2 under oxygen–glucose deprivation conditions
			Xu J, Ji T, Li G, Zhang H, Zheng Y, Li M, Ma J, Li Y, Chi G
Journal of Neuroinflammation 2022;19(1)
		Journal of Neuroinflammation 2022;19(1)
Lamina-specific properties of spinal astrocytes.
			Kronschläger MT, Siegert ASM, Resch FJ, Rajendran PS, Khakh BS, Sandkühler J
Glia 2021 Jul;69(7):1749-1766
		Glia 2021 Jul;69(7):1749-1766
MicroRNA suppression of stress-responsive NDRG2 during dexamethasone treatment in skeletal muscle cells
			Mir B, Islam R, Kalanon M, Russell A, Foletta V
BMC Molecular and Cell Biology 2019;20(1)
		BMC Molecular and Cell Biology 2019;20(1)
Abundant NDRG2 Expression Is Associated with Aggressiveness and Unfavorable Patients' Outcome in Basal-Like Breast Cancer.
			Kloten V, Schlensog M, Eschenbruch J, Gasthaus J, Tiedemann J, Mijnes J, Heide T, Braunschweig T, Knüchel R, Dahl E
PloS one 2016;11(7):e0159073
		PloS one 2016;11(7):e0159073
NDRG2 promotes myoblast proliferation and caspase 3/7 activities during differentiation, and attenuates hydrogen peroxide – But not palmitate‐induced toxicity
			Anderson K, Russell A, Foletta V
FEBS Open Bio 2015;5(1):668-681
		FEBS Open Bio 2015;5(1):668-681
Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells
			Stadler C, Rexhepaj E, Singan V, Murphy R, Pepperkok R, Uhlén M, Simpson J, Lundberg E
Nature Methods 2013;10(4):315-323
		Nature Methods 2013;10(4):315-323
NDRG4 Is Required for Cell Cycle Progression and Survival in Glioblastoma Cells
			Schilling S, Hjelmeland A, Radiloff D, Liu I, Wakeman T, Fielhauer J, Foster E, Lathia J, Rich J, Wang X, Datto M
Journal of Biological Chemistry 2009;284(37):25160-25169
		Journal of Biological Chemistry 2009;284(37):25160-25169
Tissue profiling of the mammalian central nervous system using human antibody-based proteomics.
			Mulder J, Björling E, Jonasson K, Wernérus H, Hober S, Hökfelt T, Uhlén M
Molecular & cellular proteomics : MCP 2009 Jul;8(7):1612-22
		Molecular & cellular proteomics : MCP 2009 Jul;8(7):1612-22
Frequent promoter hypermethylation and transcriptional downregulation of the NDRG2 gene at 14q11.2 in primary glioblastoma
			Tepel M, Roerig P, Wolter M, Gutmann D, Perry A, Reifenberger G, Riemenschneider M
International Journal of Cancer 2008;123(9):2080-2086
		International Journal of Cancer 2008;123(9):2080-2086
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					Supportive validation
					
									
				
				- Submitted by
 - Atlas Antibodies (provider)
 - Main image
 
- Experimental details
 - Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm, cytosol & microtubule organizing center.
 - Sample type
 - Human
 
							
					Supportive validation
					
									
				
		
		- Submitted by
 - Atlas Antibodies (provider)
 - Enhanced method
 - Orthogonal validation
 - Main image
 
- Experimental details
 - Immunohistochemistry analysis in human salivary gland and pancreas tissues using HPA002896 antibody. Corresponding NDRG2 RNA-seq data are presented for the same tissues.
 - Sample type
 - Human
 - Protocol
 - Protocol