Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- HPA002896 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA002896, RRID:AB_1079459
- Product name
- Anti-NDRG2
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human NDRG2, Gene description: NDRG family member 2, Alternative Gene Names: KIAA1248, SYLD, Validated applications: ICC, IHC, WB, Uniprot ID: Q9UN36, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.3 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Developmentally Arrested Basket/Stellate Cells in Postnatal Human Brain as Potential Tumor Cells of Origin for Cerebellar Hemangioblastoma in von Hippel-Lindau Patients
Lactate attenuates astrocytic inflammation by inhibiting ubiquitination and degradation of NDRG2 under oxygen–glucose deprivation conditions
Lamina-specific properties of spinal astrocytes.
MicroRNA suppression of stress-responsive NDRG2 during dexamethasone treatment in skeletal muscle cells
Abundant NDRG2 Expression Is Associated with Aggressiveness and Unfavorable Patients' Outcome in Basal-Like Breast Cancer.
NDRG2 promotes myoblast proliferation and caspase 3/7 activities during differentiation, and attenuates hydrogen peroxide – But not palmitate‐induced toxicity
Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells
NDRG4 Is Required for Cell Cycle Progression and Survival in Glioblastoma Cells
Tissue profiling of the mammalian central nervous system using human antibody-based proteomics.
Frequent promoter hypermethylation and transcriptional downregulation of the NDRG2 gene at 14q11.2 in primary glioblastoma
Shively S, Edwards N, MacDonald T, Johnson K, Diaz-Rodriguez N, Merrill M, Vortmeyer A
Journal of Neuropathology & Experimental Neurology 2022;81(11):885-899
Journal of Neuropathology & Experimental Neurology 2022;81(11):885-899
Lactate attenuates astrocytic inflammation by inhibiting ubiquitination and degradation of NDRG2 under oxygen–glucose deprivation conditions
Xu J, Ji T, Li G, Zhang H, Zheng Y, Li M, Ma J, Li Y, Chi G
Journal of Neuroinflammation 2022;19(1)
Journal of Neuroinflammation 2022;19(1)
Lamina-specific properties of spinal astrocytes.
Kronschläger MT, Siegert ASM, Resch FJ, Rajendran PS, Khakh BS, Sandkühler J
Glia 2021 Jul;69(7):1749-1766
Glia 2021 Jul;69(7):1749-1766
MicroRNA suppression of stress-responsive NDRG2 during dexamethasone treatment in skeletal muscle cells
Mir B, Islam R, Kalanon M, Russell A, Foletta V
BMC Molecular and Cell Biology 2019;20(1)
BMC Molecular and Cell Biology 2019;20(1)
Abundant NDRG2 Expression Is Associated with Aggressiveness and Unfavorable Patients' Outcome in Basal-Like Breast Cancer.
Kloten V, Schlensog M, Eschenbruch J, Gasthaus J, Tiedemann J, Mijnes J, Heide T, Braunschweig T, Knüchel R, Dahl E
PloS one 2016;11(7):e0159073
PloS one 2016;11(7):e0159073
NDRG2 promotes myoblast proliferation and caspase 3/7 activities during differentiation, and attenuates hydrogen peroxide – But not palmitate‐induced toxicity
Anderson K, Russell A, Foletta V
FEBS Open Bio 2015;5(1):668-681
FEBS Open Bio 2015;5(1):668-681
Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells
Stadler C, Rexhepaj E, Singan V, Murphy R, Pepperkok R, Uhlén M, Simpson J, Lundberg E
Nature Methods 2013;10(4):315-323
Nature Methods 2013;10(4):315-323
NDRG4 Is Required for Cell Cycle Progression and Survival in Glioblastoma Cells
Schilling S, Hjelmeland A, Radiloff D, Liu I, Wakeman T, Fielhauer J, Foster E, Lathia J, Rich J, Wang X, Datto M
Journal of Biological Chemistry 2009;284(37):25160-25169
Journal of Biological Chemistry 2009;284(37):25160-25169
Tissue profiling of the mammalian central nervous system using human antibody-based proteomics.
Mulder J, Björling E, Jonasson K, Wernérus H, Hober S, Hökfelt T, Uhlén M
Molecular & cellular proteomics : MCP 2009 Jul;8(7):1612-22
Molecular & cellular proteomics : MCP 2009 Jul;8(7):1612-22
Frequent promoter hypermethylation and transcriptional downregulation of the NDRG2 gene at 14q11.2 in primary glioblastoma
Tepel M, Roerig P, Wolter M, Gutmann D, Perry A, Reifenberger G, Riemenschneider M
International Journal of Cancer 2008;123(9):2080-2086
International Journal of Cancer 2008;123(9):2080-2086
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human salivary gland and pancreas tissues using HPA002896 antibody. Corresponding NDRG2 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol