Tissue expression
Cell line expression
NDRG2
gene productKIAA1248, SYLD
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]
- Description
- NDRG family member 2
- Tissue specificity
- Tissue enhanced (brain, salivary gland, skeletal muscle)
- Subcell location
- Nucleoplasm, Centriolar satellite, Cytosol
- Predicted location
- Intracellular, Membrane
- Protein family
- Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
- Chromosome
- 14:q11.2 (21016763 - 21070872)
- Ensembl ID
- ENSG00000165795 (ver. 103.38)
- Orthologs
- Mouse Ndrg2: ENSMUSG00000004558
- UniProt
- Q9UN36
- neXtProt
- NX_Q9UN36
Human splice variants
Mouse splice variants
Ensembl | UniProt | RefSeq | Entrez |
---|---|---|---|
ENSMUST00000004673 ENSMUSP00000004673 |
Q9QYG0.154 Q9QYG0 | NP_001347198.1 NP_001347198 NP_001347194.1 NP_001347194 NP_001347197.1 NP_001347197 NP_001347196.1 NP_001347196 NP_038892.1 NP_038892 NP_001347195.1 NP_001347195 NP_001347193.1 NP_001347193 | Ndrg2 29811 |
ENSMUST00000111632 ENSMUSP00000107259 |
Q9QYG0.154 Q9QYG0 | NP_001347201.1 NP_001347201 NP_001347200.1 NP_001347200 NP_001347203.1 NP_001347203 NP_001347202.1 NP_001347202 NP_001139431.1 NP_001139431 NP_001347205.1 NP_001347205 NP_001347199.1 NP_001347199 | Ndrg2 29811 |
ENSMUST00000226184 ENSMUSP00000154135 |
Ndrg2 29811 | ||
ENSMUST00000226528 ENSMUSP00000154716 |
Ndrg2 29811 | ||
ENSMUST00000227237 ENSMUSP00000153938 |
Ndrg2 29811 | ||
ENSMUST00000227402 ENSMUSP00000154279 |
Ndrg2 29811 | ||
ENSMUST00000228164 ENSMUSP00000153830 |
Ndrg2 29811 |
* nTPM: Normalized TPM levels represent consensus gene expression calculated using two data sets. Read more
RNA data sourced from Human Protein Atlas.