Antibody data
- Antibody Data
- Antigen structure
- References [17]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 15597-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15597-1-AP, RRID:AB_2141973
- Product name
- MCM3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MCM3 antibody (Cat. #15597-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references YTHDF1 promotes gallbladder cancer progression via post-transcriptional regulation of the m6A/UHRF1 axis.
RNF125‑mediated ubiquitination of MCM6 regulates the proliferation of human liver hepatocellular carcinoma cells.
Systematic analysis of expression and prognostic significance for MCM family in head and neck squamous cell carcinoma.
Pyrroloquinoline quinone alleviates natural aging-related osteoporosis via a novel MCM3-Keap1-Nrf2 axis-mediated stress response and Fbn1 upregulation.
Rac GTPase activating protein 1 promotes the glioma growth by regulating the expression of MCM3.
ACTL6A deficiency induces apoptosis through impairing DNA replication and inhibiting the ATR-Chk1 signaling in glioblastoma cells.
MCMBP promotes the assembly of the MCM2-7 hetero-hexamer to ensure robust DNA replication in human cells.
The influence of phenolic environmental estrogen on the transcriptome of uterine leiomyoma cells: A whole transcriptome profiling-based analysis.
Targeted Protein Depletion Using the Auxin-Inducible Degron 2 (AID2) System.
ICAM1 initiates CTC cluster formation and trans-endothelial migration in lung metastasis of breast cancer.
S-Adenosylmethionine Affects Cell Cycle Pathways and Suppresses Proliferation in Liver Cells.
Expression and prognostic significance of MCM-3 and MCM-7 in salivary adenoid cystic carcinoma.
Biocompatible PEGylated Gold nanorods function As cytokinesis inhibitors to suppress angiogenesis.
MCM7 expression is correlated with histological subtypes of lung adenocarcinoma and predictive of poor prognosis.
Lamin B2 binding to minichromosome maintenance complex component 7 promotes non-small cell lung carcinogenesis.
Minichromosome maintenance complex component 7 has an important role in the invasion of papillary urothelial neoplasia.
Elevated transcriptional co-activator p102 mediates angiotensin II type 1 receptor up-regulation and extracellular matrix overproduction in the high glucose-treated rat glomerular mesangial cells and isolated glomeruli.
Chen J, Bai X, Zhang W, Yan Z, Liu Y, Zhou S, Wu X, He X, Yang A
Journal of cellular and molecular medicine 2024 May;28(9):e18328
Journal of cellular and molecular medicine 2024 May;28(9):e18328
RNF125‑mediated ubiquitination of MCM6 regulates the proliferation of human liver hepatocellular carcinoma cells.
Feng X, Song D, Liu X, Liang Y, Jiang P, Wu S, Liu F
Oncology letters 2024 Mar;27(3):105
Oncology letters 2024 Mar;27(3):105
Systematic analysis of expression and prognostic significance for MCM family in head and neck squamous cell carcinoma.
Sun E, Peng L, Liu Z, Yan Z, Chen M, Zheng J
Histology and histopathology 2024 Apr;39(4):471-482
Histology and histopathology 2024 Apr;39(4):471-482
Pyrroloquinoline quinone alleviates natural aging-related osteoporosis via a novel MCM3-Keap1-Nrf2 axis-mediated stress response and Fbn1 upregulation.
Li J, Zhang J, Xue Q, Liu B, Qin R, Li Y, Qiu Y, Wang R, Goltzman D, Miao D, Yang R
Aging cell 2023 Sep;22(9):e13912
Aging cell 2023 Sep;22(9):e13912
Rac GTPase activating protein 1 promotes the glioma growth by regulating the expression of MCM3.
Jia B, Jiang Y, Huan Y, Han Y, Liu W, Liu X, Wang Y, He L, Cao Z, He X, Zhang K, Gu J, Guo Q, Fei Z
Translational oncology 2023 Nov;37:101756
Translational oncology 2023 Nov;37:101756
ACTL6A deficiency induces apoptosis through impairing DNA replication and inhibiting the ATR-Chk1 signaling in glioblastoma cells.
Hu X, Pei D, Ci M, Zhang G, Li B, Wang J, Shen Y, Zhai X, Liang P, Cui H
Biochemical and biophysical research communications 2022 Apr 9;599:148-155
Biochemical and biophysical research communications 2022 Apr 9;599:148-155
MCMBP promotes the assembly of the MCM2-7 hetero-hexamer to ensure robust DNA replication in human cells.
Saito Y, Santosa V, Ishiguro KI, Kanemaki MT
eLife 2022 Apr 19;11
eLife 2022 Apr 19;11
The influence of phenolic environmental estrogen on the transcriptome of uterine leiomyoma cells: A whole transcriptome profiling-based analysis.
Li Z, Yin H, Shen Y, Ren M, Xu X
Ecotoxicology and environmental safety 2021 Mar 15;211:111945
Ecotoxicology and environmental safety 2021 Mar 15;211:111945
Targeted Protein Depletion Using the Auxin-Inducible Degron 2 (AID2) System.
Saito Y, Kanemaki MT
Current protocols 2021 Aug;1(8):e219
Current protocols 2021 Aug;1(8):e219
ICAM1 initiates CTC cluster formation and trans-endothelial migration in lung metastasis of breast cancer.
Taftaf R, Liu X, Singh S, Jia Y, Dashzeveg NK, Hoffmann AD, El-Shennawy L, Ramos EK, Adorno-Cruz V, Schuster EJ, Scholten D, Patel D, Zhang Y, Davis AA, Reduzzi C, Cao Y, D'Amico P, Shen Y, Cristofanilli M, Muller WA, Varadan V, Liu H
Nature communications 2021 Aug 11;12(1):4867
Nature communications 2021 Aug 11;12(1):4867
S-Adenosylmethionine Affects Cell Cycle Pathways and Suppresses Proliferation in Liver Cells.
Yan L, Liang X, Huang H, Zhang G, Liu T, Zhang J, Chen Z, Zhang Z, Chen Y
Journal of Cancer 2019;10(18):4368-4379
Journal of Cancer 2019;10(18):4368-4379
Expression and prognostic significance of MCM-3 and MCM-7 in salivary adenoid cystic carcinoma.
Wen QL, Zhu SM, Jiang LH, Xiang FY, Yin WJ, Qian YY, Huang YQ, Yin KX, Zhu X, Ge MH
International journal of clinical and experimental pathology 2018;11(11):5359-5369
International journal of clinical and experimental pathology 2018;11(11):5359-5369
Biocompatible PEGylated Gold nanorods function As cytokinesis inhibitors to suppress angiogenesis.
Song H, Guo T, Zhao Z, Wei Y, Luo H, Weng W, Zhang R, Zhong M, Chen C, Su J, Shen W
Biomaterials 2018 Sep;178:23-35
Biomaterials 2018 Sep;178:23-35
MCM7 expression is correlated with histological subtypes of lung adenocarcinoma and predictive of poor prognosis.
Wang H, Zhou C, Su B, Teng G, Zheng Y, Zhou X, Guo L, Xu F, Wang X
International journal of clinical and experimental pathology 2017;10(12):11747-11753
International journal of clinical and experimental pathology 2017;10(12):11747-11753
Lamin B2 binding to minichromosome maintenance complex component 7 promotes non-small cell lung carcinogenesis.
Ma Y, Fei L, Zhang M, Zhang W, Liu X, Wang C, Luo Y, Zhang H, Han Y
Oncotarget 2017 Dec 1;8(62):104813-104830
Oncotarget 2017 Dec 1;8(62):104813-104830
Minichromosome maintenance complex component 7 has an important role in the invasion of papillary urothelial neoplasia.
Guan B, Wang X, Yang J, Zhou C, Meng Y
Oncology letters 2015 Aug;10(2):946-950
Oncology letters 2015 Aug;10(2):946-950
Elevated transcriptional co-activator p102 mediates angiotensin II type 1 receptor up-regulation and extracellular matrix overproduction in the high glucose-treated rat glomerular mesangial cells and isolated glomeruli.
Wang Z, Ni J, Shao D, Liu J, Shen Y, Zhou L, Huang Y, Yu C, Wang J, Xue H, Lu L
European journal of pharmacology 2013 Feb 28;702(1-3):208-17
European journal of pharmacology 2013 Feb 28;702(1-3):208-17
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MCM3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MCM3. This antibody recognizes human,mouse,rat antigen. The MCM3 antibody has been validated for the following applications: ELISA, WB analysis.