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Cell line expression
Protein structure
MCM3
Minichromosome maintenance complex component 3The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2018]
Top validated antibodies |
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| GeneTex |  GTX110241 |
2 references | Polyclonal |
WB
ICC
IP
IHC
ChIP
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| Invitrogen Antibodies | PA5-29106 |
Polyclonal |
WB
ICC
IP
IHC
ChIP
OA
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| Proteintech Group | 15597-1-AP |
17 references | Polyclonal |
WB
EL
IP
IHC
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| antibodies-online | ABIN393375 |
5 references | Monoclonal |
WB
EL
ICC
IHC
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| LSBio | LS-C287112 |
Polyclonal |
WB
IP
IHC
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