Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-B10633 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Mouse anti-Human MCM3 monoclonal antibody, clone 5G8
- Antibody type
- Monoclonal
- Description
- The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 5G8
- Vial size
- 50 _g
- Storage
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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