NBP2-75748-20ug

antibody from Novus Biologicals
Targeting: BCL6 BCL5, BCL6A, LAZ3, ZBTB27, ZNF51
Provider product page for NBP2-75748-20ug

Antibody data

Product number
NBP2-75748-20ug - Provider product page
Provider
Novus Biologicals
Product name
Mouse Monoclonal Bcl-6 Antibody
Antibody type
Monoclonal
Description
Protein A or G purified. Recognizes a protein of 95 kDa, which is identified as Bcl-6. Antibody to bcl-6 is helpful in a number of diagnostic settings: (1) In the differential diagnosis of small B-cell lymphoma. Follicular lymphoma will show bcl-6 (and CD10) positivity whereas other small B-cell lymphomas are usually negative. (2) Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. (3) Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ( L&H ) cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.
Reactivity
Human
Host
Mouse
Isotype
IgG
Vial size
20 ug
Concentration
0.2 mg/ml
Storage
Store at 4C.
BCL6 protein structure - NBP2-75748-20ug shown in red.