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Protein structure
BCL6
BCL6 transcription repressorBCL5, BCL6A, LAZ3, ZBTB27, ZNF51
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
Top validated antibodies |
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| Invitrogen Antibodies |  PA5-27390 |
Polyclonal |
WB
ICC
IP
IHC
ChIP
OA
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| Proteintech Group | 21187-1-AP |
16 references | Polyclonal |
WB
EL
IP
IHC
FC
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| GeneTex | GTX101338 |
1 references | Polyclonal |
WB
IP
IHC
ChIP
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| antibodies-online | ABIN2841500 |
2 references | Polyclonal |
WB
IHC
FC
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| LSBio | LS-C387070 |
Polyclonal |
WB
EL
IHC
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