ABIN659194

antibody from antibodies-online

Targeting: BCL6 BCL5, BCL6A, LAZ3, ZBTB27, ZNF51

Western blot (Supportive data in Antibodypedia)

Immunocytochemistry (Data presented on provider website)

Antibody Data

Product number

ABIN659194

Provider

antibodies-online

Product name

anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 676-704), (C-Term) antibody

Antibody type

Monoclonal

Description

Ascites

Reactivity

Human

Host

Mouse

Epitope

AA 676-704, C-Term

Isotype

IgG

Antibody clone number

305CT16-3-3

Vial size

0.1 mL

Storage

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Handling

Avoid freeze-thaw cycles.

References

Submitted references

A novel mechanism involving coordinated regulation of nuclear levels and acetylation of NF-YA and Bcl6 activates RGS4 transcription.

Yang J, Huang J, Chatterjee TK, Twait E, Fisher RA
The Journal of biological chemistry 2010 Sep 24;285(39):29760-9

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BCL6 is required for differentiation of Ig-like transcript 3-Fc-induced CD8+ T suppressor cells.

Chang CC, Vlad G, D'Agati VD, Liu Z, Zhang QY, Witkowski P, Torkamani AA, Stokes MB, Ho EK, Cortesini R, Suciu-Foca N
Journal of immunology (Baltimore, Md. : 1950) 2010 Nov 15;185(10):5714-22

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BCL6 promoter interacts with far upstream sequences with greatly enhanced activating histone modifications in germinal center B cells.

Ramachandrareddy H, Bouska A, Shen Y, Ji M, Rizzino A, Chan WC, McKeithan TW
Proceedings of the National Academy of Sciences of the United States of America 2010 Jun 29;107(26):11930-5

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DNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas.

Lai AY, Fatemi M, Dhasarathy A, Malone C, Sobol SE, Geigerman C, Jaye DL, Mav D, Shah R, Li L, Wade PA
The Journal of experimental medicine 2010 Aug 30;207(9):1939-50

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB