17572-1-AP

antibody from Proteintech Group

Targeting: MAPK10 JNK3, p493F12, p54bSAPK, PRKM10

Provider product page for 17572-1-AP

Western blot

ELISA

Immunocytochemistry

Antibody data

Antibody Data
Antigen structure
References [22]
Comments [0]
Validations
Western blot [1]
Immunocytochemistry [1]

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Product number: 17572-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#17572-1-AP, RRID:AB_2266214
Product name: MAPK10 antibody
Antibody type: Polyclonal
Description: KD/KO validated MAPK10 antibody (Cat. #17572-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

MAPK10 protein structure - 17572-1-AP shown in red.

Submitted references Cadmium-induced annulus fibrosus cell senescence contributes to intervertebral disc degeneration via the JNK/p53 signaling pathway.

Liu X, Zhao W, Hu M, Zhang Y, Wang J, Zhang L
Iranian journal of basic medical sciences 2024;27(5):588-595

Nucleolin lactylation contributes to intrahepatic cholangiocarcinoma pathogenesis via RNA splicing regulation of MADD.

Yang L, Niu K, Wang J, Shen W, Jiang R, Liu L, Song W, Wang X, Zhang X, Zhang R, Wei D, Fan M, Jia L, Tao K
Journal of hepatology 2024 Oct;81(4):651-666

Pongamol Prevents Neurotoxicity via the Activation of MAPKs/Nrf2 Signaling Pathway in H(2)O(2)-Induced Neuronal PC12 Cells and Prolongs the Lifespan of Caenorhabditis elegans.

Wu S, Miao J, Zhu S, Wu X, Shi J, Zhou J, Xing Y, Hu K, Ren J, Yang H
Molecular neurobiology 2024 Oct;61(10):8219-8233

D-mannose alleviates intervertebral disc degeneration through glutamine metabolism.

Dong ZL, Jiao X, Wang ZG, Yuan K, Yang YQ, Wang Y, Li YT, Wang TC, Kan TY, Wang J, Tao HR
Military Medical Research 2024 May 6;11(1):28

D-arabinose induces cell cycle arrest by promoting autophagy via p38 MAPK signaling pathway in breast cancer.

Tang Z, Song H, Qin S, Tian Z, Zhang C, Zhou Y, Cai R, Zhu Y
Scientific reports 2024 May 16;14(1):11219

Fisetin Alleviates Inflammation and Oxidative Stress in Deep Vein Thrombosis via MAPK and NRF2 Signaling Pathway.

Liu H, Lu Q
International journal of molecular sciences 2024 Mar 27;25(7)

Discovery of novel osthole derivatives exerting anti-inflammatory effect on DSS-induced ulcerative colitis and LPS-induced acute lung injury in mice.

Zhou Y, Du Z, Wu Q, Guo M, Chen Z, Sun C, Li X, Zou Y, Zheng Z, Chen P, Cho WJ, Cho YC, Chattipakorn N, Wang Y, Liang G, Tang Q
European journal of medicinal chemistry 2024 Mar 15;268:116252

Study on the effect and mechanism of Zhenzhu Tongluo pills in treating diabetic peripheral neuropathy injury.

Dong P, Zhou L, Wang X, Xue L, Du Y, Cui R
European journal of medical research 2024 Mar 1;29(1):149

Orientin alleviates the inflammatory response in psoriasis like dermatitis in BALB/c mice by inhibiting the MAPK signaling pathway.

Long Q, Ma T, Wang Y, Chen S, Tang S, Wang T, Zhou Y, Xu K, Wan P, Cao Y
International immunopharmacology 2024 Jun 15;134:112261

Gestational exposure to 1-NP induces ferroptosis in placental trophoblasts via CYP1B1/ERK signaling pathway leading to fetal growth restriction.

Yu S, Mu Y, Wang K, Wang L, Wang C, Yang Z, Liu Y, Li S, Zhang M
Chemico-biological interactions 2024 Jan 5;387:110812

Protective effects of Pt-N-C single-atom nanozymes against myocardial ischemia-reperfusion injury.

Ye T, Chen C, Wang D, Huang C, Yan Z, Chen Y, Jin X, Wang X, Ding X, Shen C
Nature communications 2024 Feb 23;15(1):1682

SPOCK2 modulates neuropathic pain by interacting with MT1-MMP to regulate astrocytic MMP-2 activation in rats with chronic constriction injury.

Wang C, Xu Y, Xu M, Sun C, Zhang X, Tao X, Song T
Journal of neuroinflammation 2024 Feb 22;21(1):57

Sasanquasaponin from Camellia oleifera Abel Exerts an Anti-Inflammatory Effect in RAW 264.7 Cells via Inhibition of the NF-κB/MAPK Signaling Pathways.

Zhao Y, Zhao N, Kollie L, Yang D, Zhang X, Zhang H, Liang Z
International journal of molecular sciences 2024 Feb 10;25(4)

Protective Effects of ζ-Carotene-like Compounds against Acute UVB-Induced Skin Damage.

Zhang L, Liang S, Zhang Z, Wang K, Cao J, Yao M, Qin L, Qu C, Miao J
International journal of molecular sciences 2023 Sep 12;24(18)

FDCA Attenuates Neuroinflammation and Brain Injury after Cerebral Ischemic Stroke.

Guan X, Wei D, Liang Z, Xie L, Wang Y, Huang Z, Wu J, Pang T
ACS chemical neuroscience 2023 Oct 18;14(20):3839-3854

Grape seed proanthocyanidins regulate mitophagy of endothelial cells and promote wound healing in mice through p-JNK/FOXO3a/ROS signal pathway.

Chen L, Hao L, Yanshuo C, FangFang W, Daqin C, Weidong X, Jian X, Shaodong C, Hongyu Z, Ke X
Archives of biochemistry and biophysics 2023 Nov;749:109790

Extracts of Oldenlandia diffusa protects chondrocytes via inhibiting apoptosis and associated inflammatory response in osteoarthritis.

Lou C, Lin C, Wang W, Jiang H, Cai T, Lin S, Xue X, Lin J, Pan X
Journal of ethnopharmacology 2023 Nov 15;316:116744

Obesity and dyslipidemia are associated with partially reversible modifications to DNA hydroxymethylation of apoptosis- and senescence-related genes in swine adipose-derived mesenchymal stem/stromal cells.

Glasstetter LM, Oderinde TS, Mirchandani M, Rajagopalan KS, Barsom SH, Thaler R, Siddiqi S, Zhu XY, Tang H, Jordan KL, Saadiq IM, van Wijnen AJ, Eirin A, Lerman LO
Stem cell research & therapy 2023 May 25;14(1):143

miR-137-3p Modulates the Progression of Prostate Cancer by Regulating the JNK3/EZH2 Axis.

Zang Y, Zhu J, Li Q, Tu J, Li X, Hu R, Yang D
OncoTargets and therapy 2020;13:7921-7932

Icariside II suppresses cervical cancer cell migration through JNK modulated matrix metalloproteinase-2/9 inhibition in vitro and in vivo.

Sun YS, Thakur K, Hu F, Cespedes-Acuña CL, Zhang JG, Wei ZJ
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 May;125:110013

The potential role of HO-1 in regulating the MLK3-MKK7-JNK3 module scaffolded by JIP1 during cerebral ischemia/reperfusion in rats.

Song YJ, Dai CX, Li M, Cui MM, Ding X, Zhao XF, Wang CL, Li ZL, Guo MY, Fu YY, Wen XR, Qi DS, Wang YL
Behavioural brain research 2019 Feb 1;359:528-535

Inhibition of JNK3 promotes apoptosis induced by BH3 mimetic S1 in chemoresistant human ovarian cancer cells.

Yang X, Xiang X, Xia M, Su J, Wu Y, Shen L, Xu Y, Sun L
Anatomical record (Hoboken, N.J. : 2007) 2015 Feb;298(2):386-95

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: mouse brain tissue were subjected to SDS PAGE followed by western blot with 17572-1-AP(MAPK10 antibody) at dilution of 1:1000
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunofluorescent analysis of HepG2 cells, using MAPK10 antibody 17572-1-AP at 1:25 diluiton and Rhodamine-labeled goat anti-rabbit IgG (red).
Sample type: cell line