27511-1-AP

antibody from Proteintech Group

Targeting: COPS5 CSN5, JAB1, MOV-34, SGN5

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

27511-1-AP

Provider

Proteintech Group

Product name

JAB1 antibody

Antibody type

Polyclonal

Description

JAB1 antibody (Cat. #27511-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human, mouse, rat and has been validated for the following applications: WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Berberine Derivative B68 Promotes Tumor Immune Clearance by Dual-Targeting BMI1 for Senescence Induction and CSN5 for PD-L1 Degradation.

Hu H, Wang Q, Yu D, Tao X, Guo M, Tian S, Zhang Q, Xu M, Geng X, Zhang H, Xu H, Li L, Xie S, Chen K, Zhu W, Li XW, Xu H, Li B, Zhang W, Liu S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(7):e2413122

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JAB1/CRL4B complex represses PPARG/ACSL5 expression to promote breast tumorigenesis.

Hu T, Ma T, Huo M, Liu J, Zhang D, Li Y, Chang J, Zhang M, Wang Y, Gao T, Yuan B, Wang S, Li Q, Ma X, Zhang J, Huang W, Wang Y
Cell death and differentiation 2025 Dec 12;

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The COP9 signalosome stabilized MALT1 promotes Non-Small Cell Lung Cancer progression through activation of NF-κB pathway.

Wang Y, Deng X, Xie J, Lu T, Qian R, Guo Z, Zeng X, Liao J, Ding Z, Zhou M, Niu X
Cell biology and toxicology 2024 Jun 12;40(1):45

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PLEK2 mediates metastasis and invasion via α5-nAChR activation in nicotine-induced lung adenocarcinoma.

Li Q, Li J, Wang J, Wang J, Lu T, Jia Y, Sun H, Ma X
Molecular carcinogenesis 2024 Feb;63(2):253-265

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Crosslinking-mediated Interactome Analysis Identified PHD2-HIF1α Interaction Hotspots and the Role of PHD2 in Regulating Protein Neddylation.

Ouyang H, How CY, Wang X, Yu C, Luo A, Huang L, Chen Y
bioRxiv : the preprint server for biology 2024 Dec 17;

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Alpha5 nicotinic acetylcholine receptor mediated immune escape of lung adenocarcinoma via STAT3/Jab1-PD-L1 signalling.

Zhu P, Jin Z, Kang G, Jia Y, Liu D, Zhang Q, Guo F, Jia Y, Jiao Y, Li J, Sun H, Ma X
Cell communication and signaling : CCS 2022 Aug 15;20(1):121

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COP9 Signalosome Subunit 3 Restricts Neuroinflammatory Responses During Cerebral Ischemia/Reperfusion Injury Through Stabilizing Suppressor of Cytokine Signaling 3 Protein.

Liang E, Li X, Fu W, Zhao C, Yang B, Yang Z
Neuropsychiatric disease and treatment 2021;17:1217-1227

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Identification of Key Transcription Factors and Immune Infiltration Patterns Associated With Breast Cancer Prognosis Using WGCNA and Cox Regression Analysis.

Yin X, Liu J, Wang X, Yang T, Li G, Shang Y, Teng X, Yu H, Wang S, Huang W
Frontiers in oncology 2021;11:742792

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The potential oncogenic and MLN4924-resistant effects of CSN5 on cervical cancer cells.

Zhang H, He P, Zhou Q, Lu Y, Lu B
Cancer cell international 2021 Jul 12;21(1):369