COPS5

gene product
CSN5, JAB1, MOV-34, SGN5
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq, Jul 2008]
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446 antibodies from 37 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
25 antibodies
GeneTex
8 antibodies
antibodies-online
159 antibodies
OriGene
16 antibodies
NovoPro Bioscience Inc.
5 antibodies
Boster Biological Technology
3 antibodies
Atlas Antibodies
2 antibodies
Invitrogen Antibodies
7 antibodies
LifeSpan BioSciences, Inc.
53 antibodies
Biorbyt
17 antibodies
Cell Signaling Technology, Inc
2 antibodies
Affinity Biosciences
1 antibody
Acris Antibodies GmbH
8 antibodies
Abnova Corporation
11 antibodies
Aviva Systems Biology
3 antibodies
NSJ Bioreagents
2 antibodies
Santa Cruz Biotechnology
1 antibody
Bioworld Technology, Inc
2 antibodies
St John's Laboratory
3 antibodies
ProSci
5 antibodies
RabMAbs
3 antibodies
Bethyl Laboratories
2 antibodies
Enzo Life Sciences
2 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Creative Biolabs
5 antibodies
Creative Diagnostics
8 antibodies
Arigo
2 antibodies
R&D Systems
2 antibodies
MyBioSource
9 antibodies
GenWay
10 antibodies
RayBiotech, Inc.
4 antibodies
Spring Bioscience
4 antibodies
United States Biological
39 antibodies
Sigma-Aldrich
5 antibodies
Abgent
4 antibodies
EMD Millipore
1 antibody